Glycosciences

<p>7-Xylosyl-10-deacetyltaxol is a plant chemical that is found in the needles of the Taxus cuspidata tree. This compound has been shown to inhibit prostate cancer cells and has been clinically used as an adjuvant agent for cancer treatment. 7-Xylosyl-10-deacetyltaxol binds to prostate cancer cells and inhibits their growth, which may be due to its ability to inhibit cell cycle progression at the G2/M phase transition. It also has a strong inhibitory effect on test samples from human prostate cancer cells. In addition, it inhibits enzyme activities that are involved in the biosynthesis of membrane lipids, such as phospholipase A2, arachidonate 12-lipoxygenase, and cyclooxygenase 2. 7-Xylosyl-10-deacetyltaxol also inhibits enzyme activities in cell culture that are involved in the synthesis of carbon</p>

<p>1,6:3,4-Bis-[O-(2,3-dimethoxybutane-2,3-diyl)]-2-O-trifluoromethanesulphonyl-5-O-benzolyl-myo-inositol is a Glycosylation product with CAS No. 1068089-34-8. It is a synthetic oligosaccharide that contains an Oligosaccharide sugar and a Polysaccharide saccharide. The product has been Fluorinated and Custom synthesized for Methylation. Click modification has been performed on the complex carbohydrate to produce the desired Modification in High purity.</p>

<p>The characteristic structure of pectin is a linear chain of α-(1,4)-linked D-galacturonic acid that forms the pectin-backbone, a homogalacturonan (pectic acid). The polygalacturonic acid is partly esterified with methyl groups and the free acid groups may be partly or fully neutralized with sodium, potassium or ammonium ions. The ratio of esterified galacturonic acid groups to total galacturonic acid groups - termed the degree of esterification (DE) - has vital influence on the properties of pectin, especially the solubility and the gel forming characteristics. The mechanism for gel formation with calcium ions is known as ‘The egg box’. Into this backbone, there are regions where galacturonic acid is replaced by (1,2)-linked L-rhamnose. From the rhamnose residues, sidechains of various neutral sugars branch off. This type of pectin is called rhamnogalacturonan-I (RG-I). Up to every 25th galacturonic acid in the main chain is replaced with rhamnose. Some stretches consist of alternating galacturonic acid and rhamnose – “hairy regions”, others with lower density of rhamnose – “smooth regions”. The neutral sugars are mainly D-galactose, L-arabinose and D-xylose, the types and proportions of neutral sugars varying with the origin of pectin. Another structural type of pectin is rhamnogalacturonan II (RG-II), which is a less frequent complex, highly branched polysaccharide.</p>

<p>Sulpho Lewisa Na is a complex carbohydrate that has been modified with fluorination and methylation. This product is custom synthesized, high purity, and has a CAS number. It is available for synthesis in various lengths of saccharides with a variety of modifications. Sulpho Lewisa Na can be used in the following applications: glycosylations, click modification, and methylation.</p>

<p>Pectins are regarded as linear chains of α-1,4-linked D-galacturonic acid, a homogalacturonan (pectic acid). In the products of commerce, the degree of methylation has a vital influence on the properties of pectin, especially the solubility and gel forming characteristics. Commercial high methoxy (HM) pectin has &gt; 70% of hydroxyl groups methyl esterified. HM pectin forms gels in the presence of sucrose and for this reason it is used in jams often in combination with other fruits.</p>

<p>The Blood group H type II trisaccharide methyl ester is a synthetic oligosaccharide. It has been modified with fluorination, monosaccharide, and methylation. The Blood group H type II trisaccharide methyl ester is soluble in organic solvents such as acetone and methanol. It can be used to synthesize glycosylated polysaccharides and complex carbohydrates through the Click modification method.</p>

<p>The blood group B type III/IV tetrasaccharide is a synthetic, fluorinated carbohydrate that has been custom synthesized for glycosylation and methylation. The monosaccharide of the tetrasaccharide is a hexose, which can be modified with fluorine and click chemistry. The product is a complex carbohydrate with high purity and can be used in pharmaceuticals as an antigen for immunoglobulin G (IgG) production.</p>

<p>1,2-13C-D-Mannose is a synthetic monosaccharide that is used as a building block for oligosaccharides and polysaccharides. It has been modified with fluorination, methylation, and click chemistry to yield a complex carbohydrate with high purity. The 13C isotope can be labeled in the 2 position of the mannose ring or at the C1 position of the glucose moiety.</p>

<p>α 1,4-glucoheptasaccharide derived from starch by hydrolysis and chromatography</p>

<p>This is a glycosylation product of 1,2,3-Tri-O-acetyl-4,6-O-benzylidene-b-D-glucopyranose with methyl and acetate groups. It is a synthetic oligosaccharide that has been fluorinated at the 4' position to provide protection from degradation. This product is custom synthesized for customers. It contains saccharides that are related to polysaccharides and complex carbohydrates. The compound is of high purity and does not contain any impurities. Click modification of the glucose moiety provides protection against enzymatic degradation by enzymes such as aminoglycoside N′ acetyltransferase.</p>

<p>Glycerone phosphate hemimagnesium salt hydrate is a substrate molecule that is used in the control analysis of dihydroxyacetone phosphate. Glycerone phosphate hemimagnesium salt hydrate is an optimum concentration for 3T3-L1 preadipocytes and has been shown to have an effect on energy metabolism. Glycerone phosphate hemimagnesium salt hydrate also has enzymatic activity, which can lead to neuronal death or skin cancer. This compound is a monosodium salt that can be found in cytosolic calcium, which is present in cells and helps regulate muscle contraction. Glycerone phosphate hemimagnesium salt hydrate can also be found in basic proteins that are vital for cell function.</p>

<p>2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconhydroximo-1,5-lactone is a high purity, custom synthesis sugar. This compound has been shown to have click modification, fluorination, glycosylation and methylation. 2-Acetamido-4,6-O-benzylidene-2-deoxy-D-gluconhydroximo 1,5 -lactone is also a synthetic carbohydrate. This compound has been shown to be an oligosaccharide and monosaccharide. It is saccharide with complex carbohydrate properties.</p>

<p>Lactose-sp-biotin is a complex carbohydrate that has been modified with biotin. It is synthesized by the click modification of lactose and spacer arm, followed by glycosylation with biotin. Lactose-sp-biotin is soluble in water, which makes it suitable for use as a food additive. This product can also be used for labeling and identification of biomolecules in various fields such as fluorescence, immunoassay, or immunohistochemistry.</p>

<p>Inhibitor of lysosomal acid β-glucosidase (GlcCerase/glucocerebrosidase) with IC50 in nanomolar range for wildtype and mutant enzyme. It behaves as pharmacological chaperon by binding to instable GlcCerase active site at neutral pH values and facilitating the protein folding. In acidic lysosomes, isofagomine gets release from the enzyme active site. This results in increased levels of functional glucocerebrosidase and brings therapeutic benefits to patients with Gaucher disease.</p>

<p>Ethyl b-D-thioxylopyranoside is a synthetic monosaccharide with an O-glycosidic linkage at the C-2 position. It is a complex carbohydrate that can be used in glycosylation or polysaccharide synthesis. Ethyl b-D-thioxylopyranoside can be fluorinated to give ethyl 2,3,4,5,6-pentafluorobenzoyloxybenzoate. This compound has been shown to have potent anti-inflammatory properties in animal models of asthma and arthritis.</p>

<p>Methyl 3,6-dideoxy-a-D-arabino-hexopyranoside is a fluorinated sugar analog. It is a monosaccharide that has been synthesized and modified to include an amine group for the purpose of glycosylation. Methyl 3,6-dideoxy-a-D-arabino-hexopyranoside has CAS number 6154-71-8 and can be found in the Polysaccharides category. The compound is soluble in water, ethanol, methanol, acetone, ethyl acetate and chloroform. Methyl 3,6-dideoxy-a-D-arabino-hexopyranoside has a molecular weight of 392.5 grams per mole and a density of 1.3 grams per cubic centimeter. Methyl 3,6 -dideoxy -a -D -arabino -hexopyranoside is</p>

<p>4-Chlorophenyl b-D-glucopyranoside is a synthetic, high purity, monosaccharide sugar which can be used as a reagent in the synthesis of oligosaccharides and polysaccharides. It is also used as an intermediate for glycosylation and methylation reactions. 4-Chlorophenyl b-D-glucopyranoside has an CAS number of 4756-30-3 and can be fluorinated for use in saccharide chemistry.</p>

<p>M-topolin-9-glucoside is a synthetic sugar that has been modified by the introduction of fluorine atoms at C-2, C-3, and C-4. This sugar is used to study the interactions between carbohydrates and proteins. It is also used for the synthesis of oligosaccharides as well as for glycosylation and methylation reactions. M-topolin-9-glucoside is a monosaccharide that has been glycosylated and methylated. It can be used as a replacement for glucose in some reactions due to its stability and low cost.</p>

<p>Phenyl 2,3,4-tri-O-methyl-a-L-thiorhamnopyranoside is a custom synthesis. It is an Oligosaccharide, Polysaccharide, saccharide, Carbohydrate that is Fluorinated and has a high purity. Phenyl 2,3,4-tri-O-methyl-a-L-thiorhamnopyranoside is also Modification and has Monosaccharides as well as sugar. It was synthetically made in the lab.</p>

<p>Methyl a-D-Lamarabioside heptaacetate is a synthetic, fluorinated monosaccharide derived from the natural compound D-Lamarabioside. It is used as a building block for the synthesis of novel oligosaccharides and glycosylated proteins. This product also has applications in medical research and development, such as for the design of new drugs and vaccines, as well as in biotechnology and chemical engineering. Methyl a-D-laminarabioside heptaacetate is soluble in water with a melting point of 230°C. It can be used to modify proteins with high purity by introducing glycosylation sites. This product is also useful for click chemistry reactions.</p>