Composés apparentés aux enzymes, aux peptides et aux protéines

<p>Inhibitor of protein synthesis; aminocyclitol class</p>

<p>Please enquire for more information about Estrone 3-valerate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Lithium tetrakis(pentafluorophenyl)borate - ethyl ether complex is a ligand that has the ability to bind to magnesium. The complex is highly soluble in organic solvents such as ethylene and ether, but not in water. It can be used to produce high yields of ethylene with magnesium as a co-catalyst. The complex binds to magnesium by forming a six-membered ring with the borate group and two oxygen atoms from the ether molecule. The crystal structure of this complex was determined using x-ray crystallography. This complex has been found naturally in plants such as spinach and beets, although it is not yet known what role it plays in these plants.</p>

<p>Please enquire for more information about Delta2-Cefepime etherate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glycodeoxycholic acid is a bile acid that has been shown to inhibit bacterial translocation. It is used as an adjuvant therapy in the treatment of primary sclerosing cholangitis and other inflammatory conditions of the liver, such as pancreatitis, and it has also been studied for its effects on iron homeostasis. Glycodeoxycholic acid is produced by the human body and can be found in the serum. The biosynthesis of glycodeoxycholic acid is dependent on microbial metabolism, which may be inhibited by nonsteroidal anti-inflammatory drugs. This compound has been shown to inhibit cell signaling pathways and increase sodium ion uptake into cells through inhibition of sodium-potassium ATPase activity.</p>

<p>Please enquire for more information about 11-Hydroxy dihydro loratadine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Estradiol hemihydrate is a synthetic estrogen. It binds to estrogen receptors, causing the activation of DNA transcription and synthesis of messenger RNA. Estradiol hemihydrate has been used for the treatment of various symptoms, such as menopause, osteoporosis, breast cancer, and metabolic disorders. The drug is most often administered by injection or in a polymeric matrix that dissolves slowly in the mouth. The recommended dose is between 0.5mg and 1mg per day. Estradiol hemihydrate can be detected in plasma using an analytical method called liquid chromatography-tandem mass spectrometry (LC-MS/MS).</p>

<p>Please enquire for more information about rec Human Growth Hormone (expressed in E.coli) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acridine orange hydrochloride hydrate is a fine chemical that can be used as a reagent or building block in research and other chemical reactions. It is used as a speciality chemical with CAS number 1704465-79-1. Acridine orange hydrochloride hydrate has versatile applications and is used as a reaction component or intermediate. Acridine orange hydrochloride hydrate is also useful as a scaffold to make complex compounds.</p>

<p>Acetate salt</p>

<p>Please enquire for more information about 5-Iodo-2,3-dihydro-1H-inden-2-amine hydrochloride hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cilapzapril monohydrate is the hydrated form of cilapzapril, that improves its solubility. It is a prodrug form that belongs to the group of angiotension converting enzyme inhibitors, also known as ACE inhibitors. Cilapzapril monohydrate acts as antihypertensive and inhibits the production angiotensin, a hormone that casused an increase in blood pressure due to blood vessels constriction. Cilapzapril is similar to other compounds as propranolol, atenolol, hydrochlorothiazide, captopril, enalapril, but recent studies has shown that it can also moderate the proliferative response in vessels after vascular injury.</p>

<p>Ochratoxin B is a mycotoxin that belongs to the group of toxic substances produced by fungi. It is found in animal feed and can contaminate food and water. Ochratoxin B has been shown to be genotoxic, inducing DNA damage in human serum, ochratoxin, tubule cells, and liver cells. It also inhibits the activity of complex enzymes such as DNA gyrase and topoisomerase II. The LC-MS/MS method for detecting ochratoxin B was developed based on its ability to react with an optical sensor that changes color when it binds to the substrate molecule. The hybridoma cell line was used to detect monoclonal antibodies against Ochratoxin B using a sample preparation technique with a detection sensitivity of 0.01 ng/mL.</p>

<p>Please enquire for more information about 2-Chloro-N,N-dimethylethanamine hydrochloride hydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Prednisolone is a synthetic corticosteroid that is used in the treatment of a number of lung diseases, including asthma. Prednisolone is used to decrease the inflammation and swelling around the airways and lungs. Prednisolone is used to treat certain skin conditions, such as eczema and dermatitis. This drug also decreases the activity of the immune system by inhibiting production of substances that cause inflammation. The onset of action for prednisolone is typically one day with a duration of up to two weeks. It has been shown to be more effective when taken orally than when applied topically. It may be taken with or without food and can be given as an oral or an intravenous dose. Prednisolone tablets must be dissolved in water before they are placed under the tongue (sublingual). The tablets will dissolve quickly under the tongue, releasing prednisolone into your bloodstream. Enteric-coated tablets should not be crushed or chewed</p>

<p>Tin(II) chloride dihydrate is a white or pale yellow crystalline solid. It is soluble in water and has a relatively low melting point. Tin(II) chloride dihydrate is used as an acid catalyst for the preparation of esters from ethyl trifluoroacetate, and as an intermediate for synthesizing quinoline derivatives. Tin(II) chloride dihydrate can also be used to deactivate fatty acids by reacting with them in the presence of water. The reaction vessel is heated to about 300°C to evaporate the solvent and leave a residue of tin chloride, which can then be recovered by distillation. Tin(II) chloride dihydrate has been shown to have transport properties that are similar to those of other metal chlorides at comparable concentrations.</p>

<p>Please enquire for more information about Fmoc-L-Ala-OH monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Thymosin beta10 (human, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ACTH (1-16), human including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Quinine hydrochloride dihydrate is a natural compound that has been used for centuries as a treatment for malaria. It is an effective anti-malarial agent and is also used to treat nocturnal leg cramps, although it has a low potency. Quinine hydrochloride dihydrate is active against the parasite Plasmodium falciparum in vitro. It binds to hemozoin, which is the pigment that the malaria parasites produce during digestion of hemoglobin from red blood cells. This binding inhibits the growth of the parasite and causes cell death by inhibiting protein synthesis. Quinine hydrochloride dihydrate has been shown to be genotoxic in vivo, but not in vitro. The genotoxic effects may be due to its ability to create reactive oxygen species (ROS) through photochemical reactions with light exposure and other chemical reactions, such as thermal expansion or matrix effects.</p>

<p>2-Chloro-3-ethylbenzoxazolium tetrafluoroborate is a synthetic compound that inhibits the enzyme maltase. This compound is used in the treatment of diabetic patients with intestinal maltase deficiency and has been shown to be effective in clinical studies. 2-Chloro-3-ethylbenzoxazolium tetrafluoroborate has also been shown to inhibit other enzymes, such as thiocarbamate synthetase and aminooxazoline synthetase, which are involved in the biosynthesis of chlorinated pesticides and herbicides. The chloride ion is necessary for this inhibition activity. The compound can be prepared by a preparative method that involves hexaacetate and chloride ion or by using an aglycone, trehalamine, or stereospecific method.</p>

<p>Please enquire for more information about Atrial natriuretic factor (1-28) (human) acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,1'-Dimethyl-4,4'-bipyridinium dichloride hydrate is a bipyridine with a divalent chloride. It has been shown to have synergic effects in the presence of dextran sulfate and paraquat. This compound has good photochemical properties, which are used for wastewater treatment and surface methodology. 1,1'-Dimethyl-4,4'-bipyridinium dichloride hydrate also has toxicological studies that show it does not cause any cellular toxicity or mitochondrial membrane potential changes. It also reduces potassium dichromate toxicity in glomerular filtration rate studies. This compound can be used as an analytical method for other bipyridines.</p>

<p>Tripropyl citrate is a fatty acid that is used as an antimicrobial agent. It is a solid catalyst, which can be used to synthesize citric acid and fatty alcohols. Tripropyl citrate has low energy and acts as a conditioning agent in skin care products. It also functions as a cationic surfactant, which can be found in many skin care products. This compound contains nitrogen atoms and unsaturated alkyl chains, which may help to keep the skin cells healthy.</p>

<p>Silver tetrafluoroborate (AgBF) is a chemical reagent that is used in analytical chemistry and structural analysis. It has shown to be a stable complex with organic molecules, such as fatty acids, and has been used to study the properties of these compounds. AgBF is an inorganic salt that can be synthesized by reacting silver nitrate and barium fluoride in the presence of trifluoroacetic acid. This compound has also been found to form stable complexes with organic molecules containing a hydroxyl group or nitrogen atom. The structure of AgBF has been determined through X-ray crystal structures and electron diffraction patterns. The molecule consists of two symmetric chains joined by a central disulfide bond.</p>

<p>Ammonium titanyl oxalate monohydrate is a compound that can be used as an antioxidant in a composition, including an electrophotographic composition. It has been shown to prevent photoreduction and nucleophilic attack on the surface of the photoconductor, as well as to reduce the magnitude of carboxylation reactions with transfer mechanism. Ammonium titanyl oxalate monohydrate may also be used for rechargeable batteries, which are devices that use electric current to generate chemical reactions. The addition of ammonium titanyl oxalate monohydrate to these batteries increases their capacity by reducing the number of cycles required before recharging. This compound also exhibits photocatalytic activity on metal surfaces in the presence of UV irradiation.</p>

<p>Cell-penetrating peptide derived from the third helix of the Antennapedia protein homeodomain.  Penetratin also shows antimicrobial and antifungal activity.</p>

<p>Dibutyltin dilaurate is a chemical substance that is used as a stabilizer in polyvinyl chloride (PVC) and polyurethane. It has been shown to react with potassium dichromate, methyl ethyl ketone, and plasma mass spectrometry. Dibutyltin dilaurate is not acutely toxic, but can be hazardous when exposed to high levels of it over a long period of time. The main route of exposure is through inhalation of the vapor or skin contact with the liquid form. In animal studies, dibutyltin dilaurate has been shown to cause liver damage and kidney toxicity.</p>

<p>Please enquire for more information about Cefalexin monohydrate impurity F including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The p-sulfonatocalix[4]arene hydrate is a luminescent and hydrogen-bonding molecule. It can be used to study the hydrogen bond interactions between subunits in calixarenes. The l-threonine, l-phenylalanine, and metal ion are all acceptors of hydrogen bonds. The carboxylate group and glycyl-l-leucine are both donors of hydrogen bonds. Counterions stabilize the charge on the hydrophobic groups by electrostatic interactions with water molecules. Hydrogen bonding interactions stabilize the charged groups from each other by forming a network of hydrogen bonds.</p>

<p>Magnesium bromide diethyl etherate is a magnesium salt of diethyl etherate, which is used in the preparation of caproic acid. It has been shown to be an efficient method for the synthesis of acyl halides through the reaction of aromatic hydrocarbons and chloride. The product has high melting point and is a cyclohexane ring. Magnesium bromide diethyl etherate can also be used for muscle cell proliferation and acrylate encapsulation. This product's reaction products are primary alcohols, which are useful in the production of polyurethane, polyesters, and polyamides.</p>

<p>N,N-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride is a depressant drug that inhibits the growth of bacteria by inhibiting fatty acid synthesis. It has been shown to inhibit group P2 enzymes that are involved in the production of fatty acids. In this way, it inhibits the formation and release of ATP, which is essential for bacterial growth. N,N-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride also has inhibitory properties against bacteria that cause infectious diseases. This drug is effective against Hl-60 cells and can be used as a diagnostic tool for detection sensitivity and detection time.</p>

<p>Esomeprazole magnesium dihydrate is a proton pump inhibitor that inhibits the production of stomach acid. It is a polymorphic matrix effect solid dispersion of esomeprazole and magnesium. Esomeprazole magnesium dihydrate has an optimum concentration of 3 mg/mL and exhibits two different morphologies: particle and microcrystals. The drug is used to treat gastroesophageal reflux disease, peptic ulcer disease, erosive esophagitis, pathological hypersecretory conditions and Zollinger-Ellison syndrome. Esomeprazole magnesium dihydrate also contains excipients such as magnesium stearate, erythrosine red dye, polyethylene glycol 3350, talc, titanium dioxide (E171), macrogol 6000 and sodium hydroxide.</p>

<p>Proinsulin C-Peptide is a subunit of insulin. It is produced by proteolytic cleavage of proinsulin and has been used as a diagnostic agent for pancreatic beta cell function. Proinsulin C-Peptide encompasses the amino acids from 55 to 89 in the sequence of insulin. It can be used as a diagnostic agent for type 1 diabetes mellitus, which is characterized by an autoimmune destruction of beta cells, and other diseases such as multiple myeloma and non-Hodgkin's lymphoma that are associated with decreased levels of proinsulin C-Peptide.</p>

<p>Please enquire for more information about rac-3-hexadecanamido-2-methoxypropan-1-ol phosphocholine monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about S-(-)-Aminoglutethimide D-tartrate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cholesterol Valerate is a fatty acid that has been used in the diagnosis of fatty acids. It can be obtained by synthesizing it from cholesterol and valeric anhydride. The carboxylic acid group in the molecule is responsible for its lipophilic properties, which allow it to dissolve in fats and oils. Cholesterol Valerate has a phase transition temperature of about -5 degrees Celsius, making it liquid at room temperature. This compound has been used as an excipient in pharmaceutical compositions, such as lipid emulsions and topical formulations to increase solubility. The termini of the molecule consist of hydroxyl groups that are susceptible to oxidation, making this compound unstable when exposed to air or sunlight.</p>

<p>Magnesium stearate is an excipient that is used in the pharmaceutical industry. It is a white, non-hygroscopic, free-flowing powder that is insoluble in water. Magnesium stearate has been shown to inhibit the activity of dapagliflozin, an oral anti-diabetic drug, by complexing with the active form of the drug and inhibiting it from binding to its receptor. Magnesium stearate has also been shown to have no adverse effects on renal function or autoimmune diseases when administered in doses up to 500 mg/day for 6 months.</p>

<p>Please enquire for more information about ACTH (2-24) (human, bovine, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dimethyl (2R,3R)-2,3-O-(1-Phenylethylidene)-L-tartrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Chlorogenic acid hemihydrate is a natural phenolic compound that belongs to the family of flavonol glycosides. The molecule has two caffeoylquinic acids and one chlorogenic acid functional groups, which are responsible for its antioxidant properties. Chlorogenic acid hemihydrate is soluble in water and can be used as a solid dispersion. This compound has been shown to have significant interactions with other drugs, including polymeric matrix, protocatechuic acid, and α-amyrin acetate. It also has been shown to have cell culture and in vivo model evidence of efficacy against cancer cells.</p>

<p>Nickel chloride hexahydrate is a compound that belongs to the group of inorganic compounds. It has a linear range and is used as an electrode material for electrochemical measurements. Nickel chloride hexahydrate forms a helical structure with a supramolecular assembly of the metal ions in its crystal lattice, which is stabilized by hydrogen bonding. This compound can be used in FTIR spectroscopy and deionized water as well as other electrolytes to measure the concentration of chloride, magnesium, and other ions.</p>

<p>Kisspeptin-54 is a mammalian peptide hormone that regulates the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Kisspeptin-54 has been shown to be potently immunogenic in humans and can be used as an antigen for the production of monoclonal antibodies. It is also a candidate drug for the treatment of obesity and may have neuroprotective effects. Kisspeptin-54 has been shown to reduce body mass index, which may be due to its ability to stimulate the immune system and promote antibody production against tumors. This peptide also has potent on-line binding properties that are useful in polymerase chain reactions.</p>

<p>A common chemical used in flavour and fragrances.  Synthesized from butyric acid.</p>

<p>Ochratoxin A is a mycotoxin that is produced by the Aspergillus ochraceus fungus. It has been shown to inhibit mitochondrial membrane potential and reduce long-term toxicity in rats. Ochratoxin A has also been found to be genotoxic, with a mutagenic effect on the rat liver microsomes. Ochratoxin A can be analysed using LC-MS/MS techniques and has been detected in human urine samples at concentrations of up to 1 µg/L. The carcinogenic potential of ochratoxin A has not yet been determined.</p>

<p>Native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas.<br>The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity.<br>It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide.<br>Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).</p>

<p>Betamethasone valerate related compound A is a corticosteroid compound that is used in the treatment of inflammation. It has anti-inflammatory and immunosuppressive properties, which are thought to be due to its inhibition of farnesyltransferase. Betamethasone valerate related compound A can be given as an intranasal solution or by injection. The drug substance is a mixture of betamethasone 17-valerate and betamethasone 17,21-dipropionate, which have different kinetic properties. The chemical stability of the drug substance is maintained by using a reaction mechanism involving chromatography.</p>

<p>Bis (1,5-Cyclooctadiene) rhodium(I)tetrafluoroborate (BODIPY) is a catalyst that enhances the rate of hydrosilylation reactions. This catalyst has been shown to be effective in the synthesis of aryl chlorides from amines and aldehydes with high enantioselectivity. BODIPY is also immobilized on silica gel to create an active catalyst for asymmetric synthesis. The immobilization process on silica gel is done by reacting BODIPY with ammonium formate and amines. The resulting catalyst can be used for the synthesis of functionalized organic compounds, such as pyrrolidines, tetrahydrofurans, and thiophenes.</p>

<p>Sodium hexamethylene-1,6-bisthiosulfatedihydrate is a salt of an oxide of benzene with hexamethylene 1,6-disulfate dihydrate. It has a white to off-white crystalline appearance and is used as an additive in mixtures to improve the wetting and dispersing properties of the mixture. The chemical formula for this compound is C8H4NaOS·2H2O.</p>

<p>Please enquire for more information about AQEE-30 (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>