Flavonoïdes

<p>Amentoflavone-7,7'',4',4''-tetramethyl ether is a specialized bioflavonoid derivative, which is synthesized from the natural biflavonoid amentoflavone found in various plant sources, such as Ginkgo biloba and St. John's Wort. The structural modification involving methylation enhances its pharmacokinetic properties, such as bioavailability and metabolic stability, making it a subject of interest in the scientific community.</p>

<p>4-O-Methylhelichrysetin is a flavonoid compound, which is a naturally occurring polyphenolic molecule. It is sourced from plants, particularly those in the Helichrysum genus, a group known for their medicinal properties. The mode of action encompasses its ability to modulate various biological pathways, including the inhibition of key enzymes and interference with cell signaling cascades. 4-O-Methylhelichrysetin has shown potential in downregulating pro-inflammatory cytokines and inducing apoptosis in certain cancer cell lines.</p>

<p>2-O-beta-L-Galactopyranosylorientin is a flavonoid glycoside, which is a subclass of naturally occurring polyphenolic compounds. This product is typically isolated from plant sources, notably those belonging to the family Poaceae. Its structure consists of an orientin molecule glycosylated with a galactose sugar moiety, enhancing its solubility and biological activity.</p>

<p>Rare natural product belonging to the flavone sub-group of flavonoids</p>

<p>2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one hydrate is a flavonoid compound, which is a polyphenolic molecule derived primarily from plant sources, particularly fruits, vegetables, and certain herbs. This compound functions as a potent antioxidant, neutralizing free radicals and reducing oxidative stress at the cellular level by donating hydrogen atoms, which plays a critical role in protecting biological macromolecules from damage and contributing to cellular homeostasis.</p>

<p>7,4'-Dihydroxyflavanone is a naturally occurring flavonoid, which is primarily sourced from various plant species. This compound is a type of polyphenolic molecule that often manifests in fruits, vegetables, and certain herbs. Its biosynthesis in plants is part of their secondary metabolism, where it plays roles in plant defense against pathogens and UV radiation.</p>

<p>Gossypetin-8-glucuronide is a flavonoid glucuronide, which is a type of plant secondary metabolite. It is derived from flowering plants, particularly those within the Hibiscus genus, where it serves as a glycosylated form of the flavonoid gossypetin. The glucuronidation process enhances the solubility and potential bioavailability of the compound. The mode of action of Gossypetin-8-glucuronide involves its role as a potent antioxidant, neutralizing free radicals and reducing oxidative stress at the cellular level. This activity is crucial in preventing damage to cellular structures such as lipids, proteins, and nucleic acids.</p>

<p>Rhamnetin-3-rutinoside is a specialized bioflavonoid, a type of plant-derived polyphenolic compound. It is typically sourced from various plant species, where it naturally occurs as part of the plant’s secondary metabolites. This compound functions primarily as an antioxidant, where its mode of action involves scavenging free radicals and stabilizing reactive oxygen species, thereby protecting cells from oxidative stress.</p>

<p>6'-Prenylpiscidone is an isoflavone derivative, which is a class of polyphenolic compounds primarily found in plants, particularly legumes. It is sourced from natural botanical origins, often derived from specific species known for their rich isoflavone content. The mode of action of 6'-Prenylpiscidone involves interactions with cellular targets that may influence a variety of biological pathways. These pathways are often associated with antioxidant activity, modulation of enzyme function, and potential estrogenic or anti-estrogenic effects due to its structural similarity to estrogen hormones.</p>

<p>5,6,7,8-Tetrahydroxyflavone is a naturally derived flavonoid, which is isolated from various plants known for their rich polyphenolic content. This compound belongs to the broader class of flavonoids, compounds renowned for their antioxidative properties. Its mode of action involves modulation of various cellular pathways, including the inhibition of oxidative stress and modulation of enzyme activities, which are critical for cellular homeostasis and protection.</p>

<p>Pomiferin is a polyphenolic compound, which is a bioactive flavonoid derived from the fruit of the Osage orange tree, scientifically known as Maclura pomifera. This compound is primarily extracted from the osage orange's pulp and seeds. The mode of action of pomiferin involves its potent antioxidant capabilities, which allow it to effectively scavenge reactive oxygen and nitrogen species, thereby mitigating oxidative stress. Additionally, pomiferin has demonstrated anti-inflammatory properties, likely mediated through the modulation of signaling pathways and the downregulation of pro-inflammatory cytokines.</p>

<p>3-(4-Methyl benzoyloxy)flavone is a synthetic flavonoid ester, which is derived from chemical modification of natural flavonoids. Flavonoids are a class of polyphenolic compounds commonly found in various fruits, vegetables, and beverages. The introduction of the 4-methylbenzoyloxy group offers structural diversity, which may enhance or modify the biological activities traditionally associated with flavonoids.</p>

<p>5,6,2'-Trimethoxyflavone is a naturally occurring flavone compound, which is a type of polyphenolic compound found in various botanical species. It is derived primarily from plants belonging to the genus Kaempferia, as well as other related species that are known for their diverse secondary metabolites.</p>

<p>Grosvenorine is a biochemical compound, which is a natural glycoside extracted from the fruit of Siraitia grosvenorii, commonly known as monk fruit. This compound is primarily sourced from the cucurbitaceae family of plants, renowned for their sweet-tasting fruits. The mode of action of grosvenorine involves its interaction with various metabolic pathways, exhibiting antioxidant and anti-inflammatory properties.</p>

<p>7-Hydroxy-5,8-dimethoxyflavanone is a naturally occurring flavanone, which is a subcategory of flavonoids commonly found in various plants. This compound is derived from plant sources, often isolated during phytochemical studies examining the secondary metabolites produced by flora. The mode of action of 7-Hydroxy-5,8-dimethoxyflavanone involves modulating various biochemical pathways, potentially influencing enzymatic activity and signal transduction mechanisms. This flavanone has garnered scientific interest due to its reported bioactive properties, such as antioxidant and anti-inflammatory effects. <br><br>Uses and applications of 7-Hydroxy-5,8-dimethoxyflavanone are primarily in research settings, where it is utilized to explore its potential therapeutic benefits. Scientists investigate its efficacy in cell culture and animal models to better understand its effects on human health. Research is ongoing to assess its potential applications in developing nutraceuticals or pharmaceuticals, particularly in areas concerning oxidative stress and inflammation-related disorders. The exploration of its pharmacokinetic properties, safety profile, and bioavailability remains an active area of scientific inquiry.</p>

<p>Kaempferol-3,7-dirhamnoside is a flavonoid glycoside, which is commonly found in various plant species, particularly those in the Fabaceae family. This compound is structurally composed of the flavonoid kaempferol, linked to two rhamnopyranoside sugar moieties. It is primarily sourced from plants such as Tephrosia purpurea, where it plays a role in the plant's defense mechanisms.</p>

<p>Sinocrassoside C1 is a cycloartane triterpenoid, which is a class of chemical compounds. It is derived from the plant genus Sinocrassula, known for its traditional medicinal applications. The mode of action of Sinocrassoside C1 involves interactions with specific cellular targets, potentially influencing signal transduction pathways and modulating enzyme activities. These interactions may account for its reported bioactivities, including anti-inflammatory, anti-tumor, and neuroprotective effects.</p>

<p>3'-Methoxypuerarin is a specialized isoflavone derivative, which is a type of phytochemical compound. This compound is primarily sourced from the roots of *Pueraria* species, which are well-known for their rich content of isoflavones. As an organic chemical, 3'-Methoxypuerarin exhibits potential pharmacological activity by interacting with various cellular pathways, often involving signal transduction mechanisms.</p>

<p>6,4'-Dihydroxy-5,7-dimethoxyflavanone is a naturally occurring flavanone, which is a type of polyphenolic compound commonly found in various plant species. These compounds are synthesized through plant secondary metabolic pathways and are typically located in fruits, flowers, and leaves, playing essential roles in plant defense and pigmentation.</p>

<p>2',5,6',7-Tetraacetoxyflavanone is a flavanone derivative, which is a type of flavonoid compound primarily sourced from plants, particularly citrus fruits. Its structure consists of a flavanone backbone with acetoxy groups at specific positions, which may influence its biochemical activity. Flavanones like 2',5,6',7-Tetraacetoxyflavanone are of interest in the scientific community due to their potential biological activities, including antioxidant properties.</p>

<p>7,4'-Dihydroxyhomoisoflavanone is a naturally occurring compound, classified as a homoisoflavanone, which is a type of polyphenolic compound. It is primarily sourced from plants, specifically found in certain species of the Fabaceae family. The compound is characterized by its unique structural configuration, which contributes to its bioactivity.</p>

<p>rac-Tetrahydrodaidzein is a racemic compound, which is a mixture of two enantiomers. It is derived from the reduction of the isoflavone daidzein, primarily found in soybeans and other legumes. This compound exhibits interesting pharmacological properties due to its ability to interact with estrogen receptors, functioning as a modulator of estrogenic activity. Its mode of action involves binding to these receptors, potentially influencing various estrogen-mediated physiological processes.</p>

<p>Cuneatin-7-methyl ether is a naturally occurring compound, classified as a flavonoid derivative. It is primarily sourced from certain plant species known for producing bioactive flavonoids. These plants are typically found in specific geographical regions, and the compound can be extracted through meticulous phytochemical methods.</p>

<p>Sideritoflavone is a flavonoid compound, which is a type of secondary metabolite derived from the *Sideritis* plant species. These plants, commonly found in the Mediterranean region, are traditionally used in herbal remedies. The compound is known for its potential biological and pharmacological activities, which stem from its interaction with various biochemical pathways.</p>

<p>6,7,2',3',4'-Pentamethoxyisoflavone is a naturally occurring flavonoid compound, which is derived from certain plant sources known for their rich polyphenolic content. As part of the isoflavone family, this compound is structurally similar to estrogen, allowing it to potentially interact with estrogen receptors in the body. Its mode of action includes modulating various biochemical pathways, including antioxidant and anti-inflammatory pathways, due to its ability to influence enzyme activities and cell signaling processes.</p>

<p>5,7-Dihydroxy-3',4',5'-trimethoxyflavanone is a flavanone compound, which is a type of polyphenolic compound found predominantly in the plant kingdom. This compound can be sourced from various plants, where it often occurs as part of the natural defense mechanisms to protect the organism from environmental stressors.</p>

<p>5,3'-Dihydroxyflavone is a flavonoid compound, which is a class of polyphenolic molecules. It is derived from various plants, where it occurs naturally as part of the complex biochemical repertoire involved in defense mechanisms and signaling processes. This compound acts as an antioxidant, neutralizing free radicals and reducing oxidative stress. It also exhibits potential neuroprotective effects by modulating specific signaling pathways and interacting with enzymes linked to inflammation and cellular health.</p>

<p>3'-Methoxydaidzein is an isoflavone compound, which is typically isolated from soybean sources. This compound belongs to a class of phytoestrogens, naturally occurring plant-derived compounds with estrogenic activity. 3'-Methoxydaidzein exhibits various biological activities due to its structural similarity to human estrogens, allowing it to bind to estrogen receptors. Its mode of action primarily involves modulating estrogen receptor activity, potentially influencing gene expression in estrogen-responsive tissues.</p>

<p>Podospicatin is a type of natural compound, which is derived from fungal sources. This unique compound is isolated from specific fungal species known for their ability to produce bioactive secondary metabolites. Podospicatin is characterized by its distinctive molecular structure, which contributes to its potential bioactivity.</p>

<p>Biochanin A-7-O-glucoside is a naturally occurring isoflavone glucoside, which is derived from various plants, particularly red clover and soy. It is a secondary metabolite, commonly found in legumes and other related species. The mode of action of Biochanin A-7-O-glucoside involves its structural ability to act as an antioxidant, scavenging free radicals and mitigating oxidative stress. This biochemical property allows it to influence various molecular pathways related to cell signaling and gene expression.</p>

<p>Datiscin is a flavonoid glycoside, which is a type of naturally occurring compound found in plants. It is derived from various botanical sources, notably within the Datisca genus. These compounds are characterized by a flavonoid core structure bonded to sugar moieties. The mode of action of Datiscin primarily involves its interaction with free radicals and reactive oxygen species, suggesting potential antioxidative properties. This mechanism can help mitigate oxidative stress within biological systems.</p>

Kaempferol-3-rutinoside-7-rhamnoside is a flavonoid glycoside, which is an organic compound derived from specific plant species like tea, onions, and broccoli. It primarily exists as a complex molecule formed by the bonding of kaempferol with sugar moieties—rutinoside and rhamnoside. This compound functions by modulating various cellular signaling pathways, including those involved in oxidation-reduction processes, apoptosis, and inflammation. It combats oxidative stress by scavenging free radicals, thereby providing a protective effect against cellular damage.

<p>Leucoside is a biochemical compound, which is derived from activated human leucocytes. This product is obtained through a meticulous extraction process that isolates specific bioactive molecules. Its mode of action involves the modulation of immune responses, potentially by influencing cytokine signaling pathways. Leucoside interacts with immune cells, potentially enhancing or dampening specific activities to achieve desired immunomodulatory effects.</p>

<p>4'-Hydroxywogonin is a bioactive flavonoid, which is derived primarily from the roots of the plant *Scutellaria baicalensis*. This compound is a naturally occurring flavone, a subclass of flavonoids, known for its potential therapeutic properties. The mode of action of 4'-Hydroxywogonin involves its ability to modulate various cellular signaling pathways. It is particularly noted for its anti-inflammatory and antioxidant effects, which are mediated through the inhibition of pro-inflammatory cytokines and the scavenging of free radicals, respectively.</p>

<p>7-Hydroxy-5-methoxyflavanone is a naturally occurring flavanone compound, which is derived from various plant sources. These sources often include fruits, vegetables, and certain medicinal herbs, known for their rich flavonoid content. The mode of action of 7-Hydroxy-5-methoxyflavanone primarily involves its role as an antioxidant. It helps in scavenging free radicals and reducing oxidative stress, which is a common pathway in cellular protection against damage.</p>

<p>Retusin TLC is a flavonoid compound, which is derived from natural plant sources. Flavonoids are known for their diverse biological activities, primarily due to their antioxidant properties. The mode of action of Retusin TLC involves its ability to scavenge free radicals, thereby reducing oxidative stress at the cellular level. This activity plays a crucial role in modulating various biochemical pathways, potentially leading to anti-inflammatory and anti-cancer effects.</p>

Vitexin-2''-xyloside is a bioactive flavonoid glycoside, which is derived from various plant sources such as Hawthorn and Passiflora species. This compound is part of a class of natural products known for their significant pharmacological activities. The mode of action primarily involves antioxidative mechanisms, where it mitigates oxidative stress by scavenging free radicals and modulating antioxidant enzyme activity. Additionally, it exhibits anti-inflammatory effects through the inhibition of pro-inflammatory cytokines and pathways.

Flavanone-d5 is an isotopically labeled flavonoid, which is a type of phenolic compound found in various plants. This compound is sourced from natural flavonoids that have been enriched with deuterium, an isotope of hydrogen, typically at five specific positions within the molecular structure. The mode of action involves the examination of metabolic pathways and interactions due to its stable isotopic labeling, allowing for precise tracing in biochemical assays.

<p>Kaempferol-3,7-di-O-glucoside is a naturally occurring flavonoid, which is commonly derived from various plant sources, including fruits, vegetables, and medicinal herbs. As a flavonoid, it appears predominantly in the form of glycosides, where kaempferol is conjugated with sugar moieties, enhancing its solubility and bioavailability.</p>

<p>(2R)-5,7-Dimethoxyflavanone is a natural flavonoid, which is a type of polyphenolic compound. It is derived from various plant sources, commonly found in fruits, vegetables, and certain medicinal herbs. Its structure includes a flavanone backbone with methoxy groups at specific positions, which modulate its biological activity.</p>

2',7-Dihydroxy-5,8-dimethoxyflavanone is a natural flavanone, which is a type of polyphenolic compound. It is derived from various plant sources where flavonoids are commonly found, such as fruits, vegetables, and certain herbs. This particular flavanone exhibits a unique chemical structure characterized by dihydroxy and dimethoxy functional groups, which contribute to its biological activity.

Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum

<p>Biochanin A is a naturally occurring isoflavone, which is derived from plants such as red clover and soy. This compound functions as a phytoestrogen, exerting its effects by modulating estrogen receptors, and showcases antioxidant capabilities through the scavenging of free radicals. As a result, Biochanin A holds significant interest for research in the modulation of hormonal pathways and in providing protection against oxidative stress.</p>

<p>Morusin is a naturally occurring flavonoid compound, which is derived primarily from the root bark of Morus alba, commonly known as the mulberry tree. This bioactive substance is known for its various chemical properties and its ability to modulate several biological pathways. The compound acts primarily through the inhibition of key signaling pathways, such as the NF-κB and MAPK pathways, which are involved in inflammation and cancer progression.</p>

<p>A cytotoxic biflavonoid from Toxicodendron succedaneum, Juniperus sp., and Chamaecyparis obtusa (hinoki).</p>

<p>(+)-Pinocembrin is a flavonoid compound, which is a naturally occurring phytochemical. It is predominantly sourced from propolis, a resinous substance produced by bees, and also found in various plants such as honey and ginger root. The mode of action of (+)-Pinocembrin involves its potent antioxidant and antimicrobial properties. It acts by scavenging free radicals, thereby protecting cells from oxidative stress, and it also interferes with microbial cell membranes, leading to antimicrobial effects.</p>

<p>Quercetagetin-7-O-glucoside is a flavonoid glycoside, which is a type of phytochemical compound. It is derived from various plant sources, notably plants in the Asteraceae family. The compound consists of the flavonoid quercetagetin and a glucose molecule, forming a glycoside linkage. Its mode of action primarily involves antioxidant activity, where it scavenges free radicals and chelates metal ions, thus potentially reducing oxidative stress in biological systems.</p>

<p>Quercetin-7-O-β-D-glucopyranoside is a flavonoid glycoside, which is a specialized type of bioactive compound found predominantly in various plants. Structurally, it constitutes quercetin—a well-known flavonoid—conjugated with a glucose molecule, specifically at the 7th position of the quercetin structure. This compound is primarily sourced from fruits, vegetables, and various herbs.</p>

<p>Demethylretusin is a naturally occurring flavonoid, which is derived primarily from various plant sources, including soybeans and other legumes. It functions as a bioactive compound with the capability to modulate multiple biochemical pathways. The mode of action of Demethylretusin involves interacting with cellular receptors and enzymes, ultimately influencing cell signaling pathways and exhibiting antioxidative, anti-inflammatory, and potential anticancer properties.</p>

3'-Prenylnaringenin is a potent phytoestrogen, a type of compound that is found in hops (Humulus lupulus), specifically in the female flowers or cones. This prenylflavonoid is particularly notable for its strong estrogenic activity attributed to its binding affinity to estrogen receptors. As such, it functions as an agonist, modulating estrogen receptor-mediated pathways and influencing gene expression related to estrogenic activity.

Dimoxystrobin is a fungicidal compound, which is a synthetic chemical derived from the strobilurin class of fungicides. It is sourced from natural antifungal compounds originally discovered in certain mushroom species. Dimoxystrobin's mode of action involves inhibiting mitochondrial respiration in fungi by binding to the Qo site of the cytochrome bc1 complex. This interference disrupts energy production in fungal cells, leading to their effective control and eventual death.

<p>5-Hydroxy-7,8-dimethoxyflavanone is a naturally occurring flavanone, which is typically sourced from various plant species known for their bioactive compounds. This compound falls under the category of flavonoids and exhibits distinct structural features that contribute to its biochemical activities. The source plants for this flavanone are often part of traditional medicinal systems, owing to their rich profile of secondary metabolites.</p>

<p>Velutin is a natural flavonoid, which is derived from the leaves of certain plant species, specifically from the Asteraceae family. This compound demonstrates a unique mode of action by modulating various signaling pathways involved in inflammation and oxidative stress. Velutin effectively inhibits the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and reduces the expression of pro-inflammatory cytokines, contributing to its anti-inflammatory properties.</p>

Isoflavone - 40% is a phytochemical compound, specifically classified as a type of polyphenolic plant-derived compound. It is sourced primarily from soybeans and other legumes, where it naturally occurs as part of the plant's secondary metabolites. The mode of action of isoflavones involves their ability to mimic estrogen. Due to their structural similarity to estrogen, isoflavones can bind to estrogen receptors and exert weak estrogenic effects, which are particularly relevant in humans and animals.

<p>6-Methoxyflavone is a flavonoid compound, which is a naturally occurring product found in certain plants. It is characterized by the presence of a methoxy group attached to the flavone backbone. This compound is typically extracted from plant sources such as citrus fruits and certain herbs that have a high content of polyphenolic compounds. Its mode of action involves modulating various biochemical pathways, including the inhibition of specific enzymes and interaction with cellular receptors, potentially affecting oxidative stress and inflammation pathways.</p>

<p>Myricetin-3-galactoside is a flavonoid glycoside, which is a type of secondary metabolite originating from various plant sources, including fruits, vegetables, and certain herbs. This compound forms when the flavonol, myricetin, is glycosylated with a galactose molecule. Its structure enhances the stability and solubility of myricetin, thereby modulating its bioavailability and biological activity.</p>

Morelloflavone is a natural biflavonoid compound, which is primarily isolated from the Garcinia species, belonging to the Clusiaceae family. This compound is derived from plant sources that have been traditionally used in various medicinal systems. Morelloflavone exhibits its mode of action through multiple biochemical pathways, prominently including its antioxidant activity. It effectively scavenges free radicals, thereby protecting cells from oxidative stress, which is implicated in numerous pathological conditions.

<p>Isoscutellarein is a flavonoid compound, which is naturally derived from various plant sources, including herbs and certain vegetables. It functions primarily as an antioxidant, scavenging free radicals and reducing oxidative stress within biological systems. This activity is attributed to its ability to donate hydrogen atoms or electrons, thus stabilizing reactive oxygen species (ROS).</p>

<p>3,5-Dihydroxyflavone is a flavonoid compound, which is a type of natural product commonly found in plants. This compound is derived from various plant sources, where it serves as a secondary metabolite involved in plant defense mechanisms. 3,5-Dihydroxyflavone exerts its effects through several mechanisms, including modulating oxidative stress and interacting with cellular signaling pathways. Its antioxidant properties allow it to scavenge free radicals, thereby protecting cells from oxidative damage. Additionally, it can influence various enzymes and receptors involved in cellular processes, leading to a range of biological effects.</p>

<p>Inhibitor of HSP70 and HSP27 expression</p>

<p>Flavanone hydrazone (FH) is a natural compound that has been found to have antiviral activity against a number of viruses, including the papilloma virus and picornavirus. The antiviral activity of FH is due to its ability to inhibit the shikimate pathway, which is required for the synthesis of aromatic amino acids from chorismate. This inhibition prevents the production of viral proteins, leading to cell death. FH also has an inhibitory effect on hepatitis C virus and leukoplakia by inhibiting fatty acid synthesis. It may also be used in the treatment of inflammatory diseases such as rheumatoid arthritis and ulcerative colitis.</p>

<p>3,7-Dimethoxy-3',4',5-Trihydroxyflavone is a flavonoid compound, which is derived from various plant sources known for their bioactive compounds. These plants are rich in polyphenolic substances, contributing to the compound's complex structure and functionality. The mode of action of 3,7-Dimethoxy-3',4',5-Trihydroxyflavone involves its ability to act as a potent antioxidant. It scavenges free radicals and reduces oxidative stress by neutralizing reactive oxygen species at the molecular level. Additionally, its molecular configuration allows for interactions with cellular signaling pathways, potentially influencing various biochemical processes.</p>

Diosmetin-7-neohesperidoside is a flavonoid glycoside, which is a secondary metabolite predominantly found in citrus fruits. This compound acts through various biochemical pathways, importantly exhibiting potent antioxidant and anti-inflammatory activities. Its mode of action involves the scavenging of free radicals and modulation of enzyme activities that contribute to inflammatory responses.

<p>Kaempferol-3-O-glucorhamnoside is a bioactive flavonoid glycoside, which is a naturally occurring compound found in a variety of plants. It serves as a significant molecule in the study of plant biochemistry and pharmacology. This compound is sourced from various plant species such as tea, broccoli, and other common vegetables and fruits, where it contributes to the plant's defense mechanisms against environmental stresses.</p>

<p>Alpinumisoflavone is a naturally occurring isoflavone, which is derived from plants, particularly those in the Leguminosae family. Structurally, isoflavones are a class of phytoestrogens, plant-derived compounds with estrogenic activity. Alpinumisoflavone exerts its effects primarily through its antioxidant and anti-inflammatory activities. It modulates key signaling pathways by interacting with cellular components to reduce oxidative stress and inhibit inflammatory responses, making it a valuable compound in studying cellular protection mechanisms.</p>

<p>4'-Hydroxy-7-methoxyisoflavone is a naturally occurring isoflavone, which is a type of phytoestrogen found in various plants. It is synthesized typically from plant sources and is part of a broader class of compounds known for their presence in legumes, especially soy and red clover. The mode of action of 4'-Hydroxy-7-methoxyisoflavone is primarily through its interaction with estrogen receptors, where it can exhibit weak estrogenic activity. This attribute allows it to modulate estrogenic signaling pathways, influencing cellular processes related to growth and metabolism.</p>

Jamaicin (AnCoA4), an isoflavone derived from the chickweed plant, is an inhibitor of the STIM1-Orai1 channel that blocks calcium ion influx.

<p>3'-Methoxy-3,7,4'-trihydroxyflavone is a naturally occurring flavonoid compound, which is derived from various plant sources, such as fruits, vegetables, and medicinal herbs. This compound is known for its potent antioxidant activity, which is primarily achieved through the scavenging of reactive oxygen species and the inhibition of oxidative stress pathways.</p>

<p>Iridin is an isoflavone glycoside derived primarily from the rhizomes of certain species of the Iris plant. As a phytochemical compound, its source is botanical, particularly extracted from Iris versicolor, known commonly as the Blue Flag plant. The mode of action for Iridin involves its role as a glycoside compound, which influences various biochemical pathways in the body. Glycosides like Iridin are known for their potential to modulate enzyme activities, interact with cellular signals, and participate in the process of detoxification within the liver.</p>

<p>Kaempferol-7,4'-dimethyl ether is a flavonoid derivative, which is a naturally occurring compound predominantly found in certain plant species. As a derivative of kaempferol, it is an O-methylated flavonoid, often isolated from various members of the Leguminosae family. Its mode of action involves interacting with multiple biological pathways, typically exhibiting antioxidant and anti-inflammatory properties. This potent flavonoid modulates signaling pathways and can influence cellular energy metabolism, often impacting reactive oxygen species (ROS) levels.</p>

<p>Naringenin-7-rutinoside is a flavonoid glycoside, which is naturally sourced from citrus fruits, such as grapefruits and oranges. This compound is characterized by its unique molecular structure where the flavonoid naringenin is bound to the disaccharide rutinose. The mode of action of naringenin-7-rutinoside primarily involves its antioxidant properties, which allow it to scavenge free radicals and reduce oxidative stress in biological systems.</p>

<p>Baicalin 7-b-D-glucuronide is a flavonoid metabolite, which is primarily derived from the root of the plant *Scutellaria baicalensis*, commonly known as Chinese skullcap. This compound occurs as part of the extensive array of flavonoids in traditional medicinal plants used in various ethnic medicine systems.</p>

<p>Isovitexin is a naturally occurring flavonoid compound, specifically a C-glycosyl flavone, which is found in a variety of plants, including green tea, passionflower, and barley leaves. Derived from these botanical sources, isovitexin is characterized by its structural complexity, contributing to its biological activity. The mode of action of isovitexin involves its ability to scavenge free radicals and inhibit oxidative stress. It exhibits strong antioxidant properties that allow it to stabilize reactive oxygen species (ROS), thereby preventing cellular damage. Additionally, isovitexin has been studied for its potential anti-inflammatory and neuroprotective effects, attributed to its influence on signaling pathways and enzyme activities related to inflammation and cell survival. Isovitexin is primarily utilized in the context of scientific research to explore its pharmacological potentials. Researchers study its application in fields such as neuroprotection, cardioprotection, and its role in mitigating the effects of metabolic disorders. Its broad spectrum of activity makes it a compound of interest in both the development of therapeutic agents and the enhancement of nutritional supplements.</p>

<p>Quercetin 3,4'-diglucoside is a flavonoid glycoside, which is a compound naturally derived from various plant sources, including certain fruits and vegetables. This compound is known for its significant role as an antioxidant. It operates by scavenging free radicals, thereby mitigating oxidative stress at the cellular level. This mode of action makes it a compound of interest in studies related to inflammation, aging, and chronic diseases.</p>

<p>Luteolin 7-diglucuronide is the major flavonoid isolated from Verbena officinalis and Aloysia triphylla.</p>

<p>6-Prenylpinocembrin is a prenylated flavonoid compound, which is derived from various natural sources, particularly plants such as those found in the Leguminosae family. This compound is characterized by the addition of a prenyl group to the flavonoid pinocembrin, enhancing its lipophilicity and potential biological activity.</p>

<p>Fluoxastrobin is a fungicide, which is a synthetic agricultural chemical developed primarily to combat fungal infections in crops. It belongs to the strobilurin class, derived from natural compounds produced by certain fungi. The mode of action of fluoxastrobin involves the inhibition of mitochondrial respiration in fungal cells. By targeting the cytochrome bc1 complex in the mitochondria, it effectively disrupts energy production within the pathogen, leading to its death.</p>

<p>(S)-Naringenin is a naturally occurring flavonoid compound, which is found predominantly in citrus fruits, such as grapefruits and oranges. Its source lies within the plant secondary metabolites known for their diverse biological activities. As a flavanone, (S)-naringenin acts primarily as an antioxidant, effectively scavenging reactive oxygen species and thereby protecting cells from oxidative stress. Additionally, it exhibits anti-inflammatory actions by modulating various signaling pathways and inhibiting the production of pro-inflammatory cytokines.</p>

<p>Sumatrol is a selective herbicide, which is a compound derived from synthetic sources designed to inhibit the growth of unwanted vegetation. It functions primarily by disrupting specific physiological processes in plants, specifically targeting the enzymatic pathways critical for the growth of broadleaf weeds and grasses. Its action mechanism involves the inhibition of key enzymes that lead to the cessation of cellular division and growth within the targeted plant species.</p>

<p>7-Hydroxy-2',4'-dimethoxyisoflavone is a synthetic isoflavone, which is derived from the structural modification of natural isoflavones found in various plants, such as soybeans and other legumes. It exerts its biological activity primarily through its interaction with cellular signaling pathways related to oxidative stress and inflammation. This compound functions by modulating enzyme activity, influencing the expression of genes involved in antioxidant defenses, and suppressing pro-inflammatory cytokines.</p>

<p>Cajanol is a naturally occurring compound, which is a flavonoid isolated from the plant *Cajanus cajan* (commonly known as pigeon pea). This compound is primarily extracted from the leaves and seeds of the plant through various chromatographic techniques, ensuring high purity and bioactive consistency. Cajanol functions by interacting with cellular pathways, exhibiting antioxidant and anti-inflammatory properties. It achieves this through the scavenging of free radicals and modulation of signaling pathways involved in cellular stress responses.</p>

Vitexin-4'-rhamnoside is a flavonoid glycoside, which is a compound derived from plants such as hawthorn and certain types of buckwheat. This compound belongs to the class of natural products known as flavonoid glycosides, which are well-regarded for their diverse biological activities. Vitexin-4'-rhamnoside is characterized by its ability to scavenge free radicals, thanks to its antioxidant properties. This action is primarily achieved by donating hydrogen atoms or electrons to neutralize reactive oxygen species, thereby mitigating oxidative stress.

<p>Kaempferol 6-C-glucoside is a flavonoid glycoside, which is a natural compound found in various plant sources, particularly in leaves and fruits. It is a type of C-glycosyl flavonoid, where the glucose moiety is bound directly to the carbon atom of the flavonoid skeleton, differentiating it from the more common O-glycosides.</p>

<p>5,7,3'-Trihydroxyflavone is a flavonoid compound, which is a type of polyphenolic molecule found in plants. This compound is derived from various plant sources such as fruits, vegetables, and certain herbs, where it naturally occurs as part of the plant's secondary metabolites. It exhibits several biochemical actions, predominantly due to its antioxidant properties. This involves scavenging free radicals and chelating metal ions, which contribute to oxidative stress reduction. Additionally, it may influence various signaling pathways related to cell survival and inflammation.</p>

<p>Azicemicin B exhibits mild antibacterial activity, and when administered to mice via intraperitoneal injection at a dosage of 150 mg/kg, it does not result in any acute toxicity.</p>

Bromoflavone (CJ-19784) is a flavonoid isolated from Aspergillus candidus. It demonstrates antitubercular activity against Mycobacterium tuberculosis (MTB) with an MIC90 of 1.2 μM. Additionally, Bromoflavone acts as an antifungal agent, inhibiting the growth of pathogenic fungi such as Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus with IC50 values of 0.11 μg/mL, 20 μg/mL, and 0.54 μg/mL, respectively.

<p>Calopogoniumisoflavone B is a naturally occurring isoflavone, which is a type of phytochemical compound derived primarily from Calopogonium species. This product is isolated from the plant's roots and stems, where it functions as a secondary metabolite. Isoflavones are well known for their phytoestrogenic properties, meaning they can mimic or modulate the action of estrogen in the body by binding to estrogen receptors. This mode of action allows isoflavones to potentially influence various biological pathways related to hormone regulation and cellular growth.</p>

<p>4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication. This Thermo Scientif</p>

<p>A MAP kinase inhibitor</p>

<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>

<p>Prunetin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.</p>

Flavone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

<p>Hispidulin-7-O-glucoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.</p>