Flavonoïdes

<p>7,3-Dihydroxyflavone is a potent small-molecule flavonoid, which is a naturally occurring compound sourced primarily from plants. This compound functions as a selective agonist for the TrkB receptor, which is the high-affinity receptor for brain-derived neurotrophic factor (BDNF). By mimicking BDNF, 7,3-Dihydroxyflavone activates intracellular signaling pathways that are crucial for neuronal survival, differentiation, and synaptic plasticity.</p>

<p>Gossypetin-7-glucoside is a flavonoid glycoside, which is a naturally occurring compound found primarily in plants. This substance is derived from the flavonoid gossypetin, which is a member of the flavonoid class of polyphenolic secondary metabolites in plants, predominantly sourced from cotton plants. The mode of action of gossypetin-7-glucoside is largely attributed to its antioxidant properties. It acts by scavenging free radicals, thereby reducing oxidative stress and potentially mitigating cellular damage.</p>

<p>Kaempferol is a naturally occurring flavonoid, which is a type of plant secondary metabolite, prevalent in a variety of fruits, vegetables, and plants such as kale, beans, tea, broccoli, apples, and grapes. It belongs to the class of flavonols, which are compounds that contribute to the pigments of plants. Kaempferol is typically sourced through plant extraction processes and is often found in significant amounts in dietary sources.</p>

<p>6,7-Dimethoxy-3',4',5-trihydroxyflavone is a specialized flavonoid compound, which is commonly isolated from plant sources known for their rich polyphenolic content. These compounds are typically synthesized by plants as secondary metabolites, playing critical roles in plant defense and pigmentation. The mode of action of 6,7-Dimethoxy-3',4',5-trihydroxyflavone primarily involves its potent antioxidant activity, where it effectively scavenges free radicals and inhibits oxidative stress at the cellular level. This antioxidant property is attributed to its ability to donate hydrogen atoms or electrons, thereby neutralizing potentially damaging reactive oxygen species (ROS).</p>

<p>Equol-7,4'-dimethyl ether is a bioactive compound, which is an isoflavone derivative. It is primarily sourced from certain plant-based materials through natural biosynthesis or fermentation processes. Its mode of action involves mimicking estrogenic activity, where it exhibits selective affinity for estrogen receptors, particularly ER-beta. This interaction can modulate various biological responses linked to estrogen, which are crucial for understanding its potential therapeutic effects.</p>

<p>Ficifolinol is a bioactive compound, which is a naturally occurring phenolic compound derived from the plant genus *Eucalyptus*, particularly from the species known for their rich bioactive profiles. Ficifolinol acts primarily through its antioxidant mechanisms, scavenging free radicals and inhibiting oxidative stress, thereby contributing to cellular protection and stability.</p>

<p>Daidzein is an isoflavone compound, which is a type of phytoestrogen primarily sourced from soybeans and other legumes. It exhibits estrogenic activity through its ability to bind to estrogen receptors, albeit with less potency than endogenous estrogens. This selective estrogen receptor modulator (SERM) can mimic or modulate natural estrogen effects in the body, depending on the physiological context.</p>

<p>Eriodictyol-7-neohesperidoside is a flavonoid glycoside, a type of compound that naturally occurs in certain plant species, notably within the genus Eriodictyon. This compound is a derivative of eriodictyol, which is found widely in citrus fruits. Its mode of action is primarily linked to its ability to interact with taste receptors, making it notable for its potential to modulate taste perceptions, specifically in the context of bitterness. This makes it of significant interest in the field of food science and technology.</p>

<p>3-Hydroxy-6,3',4',5'-tetramethoxyflavone is a naturally occurring flavonoid, which is derived from various plant sources, including certain species of the genus Chromolaena. It belongs to a class of polyphenolic compounds known for their potential biological activities. This flavonoid acts primarily through antioxidant mechanisms, where it scavenges free radicals and inhibits oxidative stress pathways. Additionally, it can modulate various signaling pathways, implicating roles in anti-inflammatory processes and cellular protection.</p>

<p>Swertiajaponin is a natural bioactive compound, classified as a flavonoid glycoside, which is derived from the plant Swertia japonica. Swertia japonica, a member of the Gentianaceae family, is predominantly found in East Asia, where it has been traditionally used in herbal medicine. As with many bioactive compounds, swertiajaponin exhibits its pharmacological effects through various biochemical interactions, including antioxidant, anti-inflammatory, and hepatoprotective activities. It is known to modulate cellular pathways and free radical scavenging, contributing to its therapeutic potential.</p>

<p>3-Hydroxy-6,2',4'-trimethoxyflavone is a naturally occurring flavonoid derivative, which is a type of secondary metabolite primarily found in various plant species. This compound is derived from the flavonoid family, known for their diverse biological activities and health-related benefits. The mode of action of 3-Hydroxy-6,2',4'-trimethoxyflavone involves its interaction with molecular pathways associated with antioxidant, anti-inflammatory, and potentially anti-cancer activities. It is thought to modulate signaling pathways that play crucial roles in cellular homeostasis, making it a compound of interest in pharmacological research.</p>

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<p>Quercetin 3-O-xyloside is a flavonoid glycoside, which is typically isolated from various plant sources, such as fruits, vegetables, and herbs. This compound is characterized by the presence of a quercetin molecule attached to a xylose sugar moiety, influencing its solubility and biological activity.</p>

<p>Isoliquiritin is a bioactive compound, specifically a flavonoid, which is derived from the roots of Glycyrrhiza glabra, commonly known as licorice. It possesses diverse pharmacological properties with multiple modes of action, notably influencing pathways involved in oxidative stress and inflammation. Isoliquiritin acts as an antioxidant, scavenging free radicals and reducing oxidative damage at the cellular level. Additionally, it exhibits anti-inflammatory effects by modulating the expression of inflammatory cytokines and inhibiting specific signaling pathways like NF-κB.</p>

<p>3,5,7,8,3',4'-Hexahydroxyflavone is a specialized flavonoid, which is a type of polyphenolic compound found naturally in plants. This compound is derived from various botanical sources, particularly in leaves and peels where flavonoids are abundant. The presence of multiple hydroxyl groups contributes to its potent antioxidant activity, allowing it to scavenge free radicals effectively.</p>

<p>R,S-Equol is a racemic mixture, classified as an isoflavandiol compound, which is synthesized from the metabolism of soy isoflavones, specifically daidzein, by gut microbiota. It acts as a selective estrogen receptor modulator (SERM) with a preference for estrogen receptor beta (ERβ). This compound demonstrates the ability to bind these receptors, mimicking the action of estrogen, but with selective modulation and lower activity than natural estrogen.</p>

<p>Apigenin-7-diglucuronide is a naturally occurring flavonoid derivative compound, which is primarily derived from various plant sources such as parsley, chamomile, and celery. It represents a glucuronidation product of apigenin, a process involving enzymatic attachment of glucuronic acid to the molecule, enhancing its water solubility and bioavailability.</p>

<p>Acerosin is a naturally derived antibiotic compound, sourced from Streptomyces bacteria, with a unique dual mode of action. It exhibits both antimicrobial activity and anti-inflammatory effects. The antimicrobial action is primarily achieved through disruption of bacterial cell wall synthesis, leading to bacterial cell lysis. Additionally, Acerosin modulates immune responses by inhibiting the production of pro-inflammatory cytokines, which reduces inflammation at the site of infection.</p>

<p>Liquiritin apioside is a flavonoid glycoside, which is predominantly derived from the root of Glycyrrhiza uralensis, commonly known as licorice. This compound acts primarily through its anti-inflammatory and antioxidant properties, which involve the modulation of various cellular pathways. Specifically, it influences the activity of inflammatory cytokines and oxidative stress markers, potentially inhibiting pathways such as nuclear factor-kappa B (NF-κB).</p>

4',5,7,8-Tetrahydroxyflavanone is a naturally occurring flavonoid, which is a type of polyphenolic compound found in various plants. These compounds are well-regarded for their potential health benefits and are often derived from natural sources such as fruits, vegetables, and certain herbs. The mode of action of 4',5,7,8-Tetrahydroxyflavanone involves its interaction with free radicals, effectively neutralizing them due to its antioxidant properties. By mitigating oxidative stress, it may exert a protective effect at the cellular level.

<p>Ononin is an isoflavonoid glycoside, which is derived from various plant sources, including species of the genus Ononis. It is primarily sourced from the roots and aerial parts of these plants, where it occurs as a natural constituent. The mode of action of Ononin involves its hydrolysis to form its aglycone, formononetin, which is known to exhibit estrogenic activity due to its structural similarity to estrogenic compounds.</p>

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<p>Wogonoside is a naturally occurring flavonoid glycoside, which is derived primarily from Scutellaria baicalensis, a traditional Chinese medicinal herb. It functions through its ability to modulate various biochemical pathways, demonstrating significant anti-inflammatory and anticancer properties. Wogonoside exerts its effects by inhibiting key enzymes and signaling pathways involved in inflammation, such as nuclear factor-kappa B (NF-κB), and inducing apoptosis in cancer cells through the activation of caspases and modulation of apoptosis-related proteins.</p>

<p>Daidzin is an isoflavone compound, which is a naturally occurring chemical extracted from the root of the plant Pueraria lobata, commonly known as kudzu. Its primary mode of action involves the inhibition of the enzyme aldehyde dehydrogenase (ALDH). This enzyme plays a significant role in the metabolism of alcohol, as it converts acetaldehyde, a toxic intermediate, into acetic acid, which is less harmful to the body.</p>

<p>Neoliquiritin is a flavonoid compound, which is derived from the root of the licorice plant, Glycyrrhiza glabra. This compound exhibits significant antioxidant properties through its ability to scavenge free radicals, thereby reducing oxidative stress within biological systems. Neoliquiritin is primarily utilized in scientific research to explore its potential therapeutic effects, particularly its anti-inflammatory and antioxidant activities. Its mode of action involves modulation of various cellular signaling pathways associated with inflammation and oxidative damage, making it a subject of interest in studies related to chronic diseases and skin conditions. Researchers investigate its potential in mitigating oxidative stress-related cellular damage, offering insights into its possible applications in pharmacology and dermatology.</p>

<p>6,7-Dihydroxyflavone is a small molecule flavonoid compound, which is a synthetic product derived to mimic naturally occurring substances. This compound is primarily sourced from the metabolic pathways involved in the biosynthesis of flavonoids, which are naturally found in plants. The mode of action of 6,7-Dihydroxyflavone involves the selective activation of the TrkB receptor, mimicking the action of the brain-derived neurotrophic factor (BDNF). This receptor plays a crucial role in neuronal survival, differentiation, and synaptic plasticity.</p>

<p>Orobol 5,7,3',4'-tetramethyl ether is a flavonoid derivative compound, which is synthesized from natural flavonoid sources such as plants. This compound operates primarily through its antioxidant properties, scavenging free radicals and reducing oxidative stress, which may contribute to its potential therapeutic activities.</p>

<p>Flavanone azine is a synthetic compound derived from flavonoid sources, specifically engineered through the structural manipulation of flavanone molecules. Flavonoids are naturally occurring compounds found in plants known for their diverse biological activities. The synthetic derivation allows for enhanced stability and bioavailability compared to natural counterparts.</p>

<p>Eupatorin 5-methyl ether is a bioactive compound, which is a naturally occurring flavonoid found in certain plant species. This compound is derived from various plants, including those in the Asteraceae family. Eupatorin 5-methyl ether functions primarily through modulating various biochemical pathways, exhibiting anti-inflammatory, antioxidant, and anticancer activities.</p>

<p>4'-Hydroxyflavanone is a naturally occurring flavonoid compound, which is derived from plant sources, particularly citrus fruits and other types of vegetation. The compound is characterized by its phenolic structure, which plays a significant role in its biological activity. 4'-Hydroxyflavanone exhibits its mode of action primarily through antioxidant activity, which involves scavenging reactive oxygen species and thus protecting cells from oxidative stress.</p>

<p>8-O-Methylretusin is a naturally occurring O-methylated flavonoid, which is derived from various plant sources. This compound is notable for its potential bioactive properties, including antioxidative, anti-inflammatory, and anticancer activities. The mode of action of 8-O-Methylretusin primarily involves modulation of cellular signaling pathways, such as the inhibition of reactive oxygen species and modulation of key transcription factors that regulate inflammatory and apoptotic processes.</p>

<p>3,7,2',4',5'-Pentamethoxyflavone is a naturally occurring flavonoid compound, which is a type of polyphenolic product. It is commonly found in various plant species, serving potential protective and adaptive functions within these organisms. The mode of action of 3,7,2',4',5'-Pentamethoxyflavone involves interaction with multiple biological pathways, including modulation of enzyme activity and influence over cellular signaling pathways. Its biochemical interactions often result in antioxidant, anti-inflammatory, and possible antiproliferative effects.</p>

<p>Kaempferol 3-b-glucopyranoside is a flavonoid glycoside, which is a compound typically isolated from a variety of plants, including tea, broccoli, and fruits such as apples and grapes. It represents a crucial category of secondary metabolites prevalent in the plant kingdom, often serving roles in plant defense and pigmentation. The mode of action of Kaempferol 3-b-glucopyranoside is primarily attributed to its antioxidant properties, effectively scavenging free radicals and thereby mitigating oxidative stress. Furthermore, it is known to modulate various cellular signaling pathways, including those related to apoptosis and inflammation, by influencing kinase activity and gene expression.</p>

<p>Herbacetin-8-glucoside-3-sophoroside is a flavonoid glycoside derivative, which is a bioactive compound commonly found in plant sources, particularly within the flavonoid subclass. This compound is notable for its multifunctional biological activities and potential health benefits. It is primarily sourced from plant materials, where it can be extracted and isolated for further study and application.</p>

<p>Beta-Naphthoflavone is a synthetic polycyclic aromatic compound, which is a laboratory-created substance designed to mimic naturally occurring compounds. It is a model compound widely used in scientific research due to its ability to induce specific enzyme pathways. Beta-Naphthoflavone primarily affects the aryl hydrocarbon receptor (AhR) pathway. Upon binding to this receptor, it modulates the expression of genes involved in xenobiotic metabolism, particularly influencing the cytochrome P450 enzymes. These enzymes play a crucial role in the metabolism of various xenobiotics and endogenous compounds.</p>

<p>3-Hydroxy-7,8,2',4'-tetramethoxyflavone is a specialized flavonoid compound, which is a type of polyphenolic metabolite derived primarily from certain plant sources. This compound belongs to a class of naturally occurring flavones that are isolated from plants known for their diverse biological activities. Its mode of action involves interacting with cellular pathways and receptors, potentially modulating enzymatic activity and affecting signal transduction processes.</p>

<p>8-Hydroxygenistein is a naturally occurring isoflavone, which is a type of polyphenolic compound. It is derived primarily from plants, particularly soybeans and other legumes. This compound exhibits its mode of action through selective inhibition of tyrosine kinase enzymes, interference with the cell cycle, and modulation of signal transduction pathways. It also acts as a potent antioxidant, scavenging free radicals and reducing oxidative stress within cells.</p>

<p>Induces cell death in human prostate cancer by disrupting mitochondria function</p>

<p>Isorhamnetin-5-O-methyl ether-3-glucoside is a flavonoid glycoside, which is a secondary metabolite typically found in various plant sources such as fruits, vegetables, and certain herbs. It is part of a larger class of compounds known as flavonoids, which are well-known for their diverse biological activities. The mode of action of Isorhamnetin-5-O-methyl ether-3-glucoside primarily involves its antioxidant properties, which allow it to neutralize free radicals and reduce oxidative stress.</p>

<p>Dillenetin is a flavonoid compound, which is derived from natural plant sources, particularly found in the genus Dillenia. It exhibits significant bioactivity with a mode of action primarily involving the modulation of cell signaling pathways. Dillenetin is known to bind to specific enzymes and receptors, influencing cellular processes such as proliferation, apoptosis, and oxidative stress responses.</p>

<p>Linarin is a naturally occurring flavonoid compound, which is primarily extracted from plant sources such as the leaves of *Buddleja davidii* and *Mentha aquatica*. This flavonoid is notable for its biological activity, which is characterized by its interaction with various enzymes and receptors involved in cellular processes.</p>

<p>Zapotin is a natural compound, which is sourced from the seeds of the Sapote Blanco (Casimiroa edulis). This organic compound exhibits its mode of action primarily through its interaction with cancerous cells. Zapotin induces apoptosis in these cells by modulating key signaling pathways, thereby preventing cell proliferation and enhancing programmed cell death. This mechanism underscores its potential as a chemopreventive agent.</p>

<p>5-Hydroxy-3',3,4',5',7-pentamethoxyflavone is a naturally occurring flavone, which is a type of flavonoid found primarily in plants. These compounds often serve as plant secondary metabolites, with potential roles in various physiological and ecological functions. This particular flavone is primarily derived from certain species within the plant kingdom, where it acts as part of the plant’s defense mechanism against pathogens and herbivores.</p>

<p>Luteolin 6,8-di-C-glucoside is a bioflavonoid compound, which is naturally derived from various plant sources, including many medicinal herbs and dietary plants. As a type of flavone glycoside, Luteolin 6,8-di-C-glucoside exhibits significant biochemical interest due to its incorporation of two glucose molecules directly attached to the luteolin backbone.</p>

<p>Cupressuflavone is a naturally occurring biflavonoid compound, which is an organic molecule composed of two flavonoid units linked together. Its source is predominantly from the Cupressaceae family, specifically from plants such as cypress trees. This compound is characterized by its potent antioxidant properties, which allow it to scavenge free radicals and reduce oxidative stress in biological systems.</p>

<p>7,4'-Dimethoxyflavone is a naturally occurring flavonoid derivative, which is found predominantly in certain plants, particularly within the citrus family. This compound is characterized by the presence of two methoxy groups attached to its flavone backbone. It functions by interacting with various biological pathways, including those involved in antioxidant and anti-inflammatory responses. Its molecular structure allows it to modulate enzyme activities and receptor interactions, although the exact mechanisms are still under study.</p>

<p>Dihydromyricetin is a flavonoid compound, which is derived from the tree Hovenia dulcis. This plant, commonly known as the Japanese raisin tree, serves as the primary natural source for this bioactive substance. The mode of action of dihydromyricetin involves modulation of neurotransmitter receptors, particularly GABA_A receptors, wherein it contributes to alleviating alcohol-induced neuroinhibition. Additionally, it enhances the liver's ability to metabolize alcohol and reduces oxidative stress by acting as an antioxidant.</p>

<p>Orobol 3',4'-dimethyl ether is a synthetic flavonoid compound, which is derived from chemical modifications of naturally occurring flavonoids. These compounds are typically found in a variety of plants and are well-known for their diverse biological activities. Orobol 3',4'-dimethyl ether is specifically engineered to enhance or modify these natural properties for potential therapeutic use.</p>

<p>Dihydro daidzein is an isoflavonoid derivative, which is a naturally occurring compound primarily sourced from the metabolic biotransformation of daidzein, a soy isoflavone. This metabolite is generated through the fermentation process by intestinal microbiota, highlighting its origin from dietary sources, particularly soy products.</p>

<p>Pinostrobin is a natural flavonoid compound, which is derived primarily from the rhizomes of plants such as the fingerroot (Boesenbergia rotunda) and various species of the Pinus genus. Its mode of action involves potent antioxidant activity, where it scavenges free radicals, thus reducing oxidative stress. Additionally, Pinostrobin exhibits antimicrobial properties by disrupting microbial cell membranes and inhibiting essential microbial enzymes.</p>