Cannabinoïdes
Les cannabinoïdes sont une classe de composés chimiques divers dérivés des acides gras ou des polykétides, qui agissent sur les récepteurs cannabinoïdes des cellules, modifiant ainsi la libération de neurotransmetteurs dans le cerveau. Principalement présents dans les plantes de cannabis, des cannabinoïdes comme le THC et le CBD sont largement étudiés pour leurs effets thérapeutiques, notamment le soulagement de la douleur, leurs propriétés anti-inflammatoires, et leur utilisation potentielle dans les maladies neurodégénératives. Chez CymitQuimica, vous trouverez une grande variété de cannabinoïdes pour la recherche en pharmacologie, neurobiologie, et chimie médicale.
299 produits trouvés pour "Cannabinoïdes"
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1,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS :<p>1,2,3,9-Tetrahydro-4H-carbazol-4-one is a cyclic ketone compound, which can be synthesized through various organic reactions involving appropriate precursors. It is often derived from indole-based substrates through catalytic hydrogenation, allowing the formation of its stable tetrahydro structure with a retained core carbazole skeleton.</p>Formule :C12H11NODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :185.23 g/molC2
CAS :<p>Positive allosteric modulator (PAM) of cannabinoid receptors CB2. The C2 modulator is the first synthetic PAM of CB2 receptors with antinociceptive properties, which were observed in a mouse model of neuropathic pain.</p>Formule :C21H24BrFN2O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :435.33 g/molGW 833972A hydrochloride
CAS :<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Formule :C18H13ClF3N5O·HClDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :444.24 g/molGW 833972A
CAS :<p>A cannabinoid receptor agonist, which binds more selectively to CB2 than CB1 receptors (1000-fold). GW833972A inhibits vagus nerve depolarization induced by tussive agents, such as hypertonic saline (EC50 = 6.5 μM), capsaicin (EC50 = 33.9 μM) or PGE2 (EC50 = 15.9 μM).</p>Formule :C18H13ClF3N5ODegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :407.78 g/molACEA, 5mg/ml solution in ethanol
CAS :<p>Cannabinoid type 1 (CB1) receptor agonist. Anti-depressant activity demonstrated in vivo alone, as well as enhancing the effect of fluoxetine. In the brain, ACEA activates CB1 receptors expressed in the mitochondria of neuronal cells to elicit neuroprotective effects. This is mediated by inducing glycogen synthase kinase-3β (GSK-3β) phosphorylation and inhibiting the opening of mitochondrial permeability transition pore (MPTP).<br>Sold by weight of solid</p>Formule :C22H36ClNODegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :365.98 g/molAnandamide
CAS :<p>Anandamide is an endogenous cannabinoid, which is a bioactive lipid mediator primarily found in the brain and peripheral organs. It is synthesized from membrane phospholipid precursors through enzymatic pathways, primarily involving the enzyme N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD). Anandamide acts as a ligand for cannabinoid receptors, mainly the CB1 receptor located in the central nervous system, and the CB2 receptor found in peripheral tissues.</p>Formule :C22H37NO2Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :347.53 g/molCannabichromenic Acid
CAS :<p>Cannabichromenic acid is a non-psychoactive phytocannabinoid and a precursor of cannabichromene1 which toxicological and pharmacological properties are unknown. Due to its structural similarity to cannabichromene, it is thought to reportedly exert anti-analgesic and anti-inflammatory activity.</p>Formule :C22H30O4Degré de pureté :Min. 95%Masse moléculaire :358.47 g/molCannabigerovarinic acid
CAS :Produit contrôlé<p>Cannabigerovarinic acid is a phytocannabinoid and the precursor to tetrahydrocannabivarinic acid, cannabidivarinic acid, and cannabichromevarinic acid1. No in vitro or in vivo pharmacological and toxicological studies have been conducted on cannabigerovarinic acid.</p>Formule :C20H28O4Degré de pureté :Min. 95%Masse moléculaire :332.43 g/molrel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-na phthalenedicarboxamide
CAS :<p>rel-(1R,2S)-8-Bromo-1-(3-bromo-4-hydroxy-5-methoxyphenyl)-1,2-dihydro-7-hydroxy-N2,N3-bis[2-(4-hydroxyphenyl)ethyl]-6-methoxy-2,3-naphthalenedicarboxamide is a synthetic chemical compound, which is derived through targeted organic synthesis and structural optimization efforts. Its source lies in advanced laboratory methodologies designed to enhance specific pharmacological properties. The mode of action is expected to involve selective interaction with particular molecular targets, potentially modulating distinct pathways related to cellular function or signaling processes.</p>Formule :C36H34Br2N2O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :782.47 g/molAPD 371
CAS :<p>A selective cannabinoid receptor type 2 (CB2) agonist. Commonly, CB2 agonists induce receptor internalization, which results in desensitization and tachyphylaxis. However, APD 371 mediates efficient recycling of internalized receptors back to the plasma membrane and thus sustains analgesic effects, upon subchronic treatment, in an osteoarthritis pain model in vivo.</p>Formule :C18H23N5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :357.41 g/molAbnormal 1''-Hydroxycannabidiol
Produit contrôléFormule :C21H30O3Couleur et forme :NeatMasse moléculaire :330.4615-(4-Hydroxypentyl)-1,3-benzenediol
CAS :Produit contrôlé<p>Applications 5-(4-Hydroxypentyl)-1,3-benzenediol is an intermediate used in the synthesis of 4''-Hydroxycannabidiol (H824830), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 4''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Formule :C11H16O3Couleur et forme :NeatMasse moléculaire :196.24Cannabigerovarinic acid
CAS :Carboxylic acid with phenol functionFormule :C20H28O4Degré de pureté :≥ 90.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :332.43Dehydroabiethylamine
CAS :<p>Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.</p>Formule :C20H31NDegré de pureté :98.79%Couleur et forme :Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidMasse moléculaire :285.472-[(9Z)-9-Octadecenyloxy]-1,3-propanediol
CAS :Produit contrôlé<p>Applications 2-[(9Z)-9-Octadecenyloxy]-1,3-propanediol, which is an endogenous cannabinoid receptor ligand.<br>References Suhara, Y. et al.: Chem. Pharm. Bull., 48, 903 (2000);<br></p>Formule :C21H42O3Couleur et forme :NeatMasse moléculaire :342.56WIN 55,212-2
CAS :Produit contrôléFormule :C27H26N2O3Couleur et forme :NeatMasse moléculaire :426.5071-(3,5-Bis(benzyloxy)phenyl)pentan-1-ol
CAS :Produit contrôléFormule :C25H28O3Couleur et forme :NeatMasse moléculaire :376.491-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications (Z)-1-(3,5-Bis(benzyloxy)phenyl)pent-1-en-3-one is a reagent in the synthesis of 3''-Hydroxycannabidiol (H824825) which is a major constituents in marijuana. 3''-Hydroxycannabidiol be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>Formule :C25H24O3Couleur et forme :NeatMasse moléculaire :372.46UR-144 N-Pentanoic Acid
CAS :Produit contrôléFormule :C21H27NO3Couleur et forme :NeatMasse moléculaire :341.44Ethyl 2-Oxopentanoate
CAS :Produit contrôlé<p>Applications Ethyl 2-oxopentanoate is used as a reagent to synthesize selective CB1 cannabinoid receptor antagonists. Ethyl 2-oxopentanoate is also used to synthesize derivatives of iminodiacid, an inhibitor of angiotensin converting enzyme.<br>References Lange, J., et al.: J. Med. Chem., 48, 1823 (2005); Vincent, M., et al.: Tetrahedron Lett., 23, 1677 (2982)<br></p>Formule :C7H12O3Couleur et forme :NeatMasse moléculaire :144.17(1S,4R)-1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol
CAS :Produit contrôlé<p>Applications 1-Methyl-4-(1-methylethenyl)-2-cyclohexen-1-ol is an acetal reagent used in the synthesis of desoxy cannabidiols and THC (T293202) related psychoactive compounds. It is formed from (+)-Limonene using a photosynthesized O2 transfer.<br>References Wilkinson, S. et al.: Tetrahedron Lett., 54, 52 (2013);<br></p>Formule :C10H16OCouleur et forme :NeatMasse moléculaire :152.23Cannabigerorcinic Acid
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Cannabigerorcinic Acid is a compound that takes part in the biosynthesis of daurichromenic acid synthase which is active in anti-HIV biosynthesis.<br>References Iijima, M. et al.: Plant Phys., 174, 2213 (2017);<br></p>Formule :C18H24O4Couleur et forme :NeatMasse moléculaire :304.382-Arachidonyl glycerol
CAS :<p>2-Arachidonyl glycerol is an endogenous cannabinoid receptor agonist, which is derived from arachidonic acid present in cellular membranes. It functions as a signaling lipid and plays a critical role in the endocannabinoid system, which is a complex network of receptors and ligands involved in maintaining physiological homeostasis.</p>Formule :C23H38O4Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :378.55 g/molS-777469
CAS :<p>S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.</p>Formule :C23H27FN2O4Couleur et forme :SolidMasse moléculaire :414.47AM-6538
CAS :<p>AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.</p>Formule :C26H25Cl2N5O4Couleur et forme :SolidMasse moléculaire :542.41NIDA 41020
CAS :<p>NIDA 41020 is a CB1 receptor antagonist.</p>Formule :C23H24Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.37PGN36
CAS :<p>PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).</p>Formule :C21H23N3O3Couleur et forme :SolidMasse moléculaire :365.43LEI-101
CAS :<p>LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.</p>Formule :C23H25FN4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :472.53GPR55 agonist 3
CAS :<p>Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.</p>Formule :C19H16F4N4Couleur et forme :SolidMasse moléculaire :376.35MJ 15
CAS :<p>MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.</p>Formule :C23H17Cl3N4ODegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :471.77LH 21
CAS :<p>LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.</p>Formule :C20H20Cl3N3Couleur et forme :SolidMasse moléculaire :408.75AM6545
CAS :<p>AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.</p>Formule :C26H23Cl2N5O3SDegré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :556.46CB1-IN-2
CAS :<p>CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.</p>Formule :C17H19Cl2N5OCouleur et forme :SolidMasse moléculaire :380.27AM404
CAS :<p>AM404 is a cannabinoid reuptake inhibitor and a TRPV (1) activator with neuroprotective and anticancer activities that blocks anandamide transport.</p>Formule :C26H37NO2Couleur et forme :SolidMasse moléculaire :395.58PM226
CAS :<p>CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.</p>Formule :C22H31NO3Couleur et forme :SolidMasse moléculaire :357.49CB1/2 agonist 4
CAS :<p>CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.</p>Formule :C27H45NO3Couleur et forme :SolidMasse moléculaire :431.65Arvanil
CAS :<p>Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.</p>Formule :C28H41NO3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :439.63COR167
CAS :<p>COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.</p>Formule :C28H38N2O2Couleur et forme :SolidMasse moléculaire :434.61CB1R Allosteric modulator 4
CAS :<p>Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.</p>Formule :C20H17N3O2SCouleur et forme :SolidMasse moléculaire :363.43GAT228
CAS :<p>GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].</p>Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39ANEB-001
CAS :<p>ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.</p>Formule :C22H24ClF3N2O2Couleur et forme :SolidMasse moléculaire :440.89UCM710
CAS :<p>UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).</p>Formule :C19H34O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.47O-2093
CAS :<p>anandamide uptake inhibitor</p>Formule :C34H43Cl2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :584.62CID1172084
CAS :<p>CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.</p>Formule :C23H18FN5O2S2Couleur et forme :SolidMasse moléculaire :479.55LBP-1
CAS :<p>LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.</p>Formule :C23H29ClN6O3Couleur et forme :SolidMasse moléculaire :472.97COR 170
CAS :<p>inverse agonist of CB2 receptors</p>Formule :C31H36N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.63CB1R Allosteric modulator 1
CAS :<p>CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.</p>Formule :C24H24ClN3OCouleur et forme :SolidMasse moléculaire :405.92Virodhamine trifluoroacetate
CAS :<p>Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.</p>Formule :C24H38F3NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.56
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