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Nucléotides

Nucléotides

Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.

Sous-catégories appartenant à la catégorie "Nucléotides"

2634 produits trouvés pour "Nucléotides"

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  • 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine

    CAS :
    <p>7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.</p>
    Formule :C16H16F3N5O3
    Masse moléculaire :383.33 g/mol

    Ref: 3D-J-700297

    1g
    À demander
    50mg
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    100mg
    À demander
    250mg
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    -Unit-gg
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  • Guanosine5'-diphosphate

    CAS :
    <p>Pyruvate kinase substrate</p>
    Formule :C10H15N5O11P2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :443.2 g/mol

    Ref: 3D-FG152484

    25mg
    252,00€
    50mg
    394,00€
    100mg
    533,00€
    250mg
    798,00€
    500mg
    1.126,00€
  • Adenosine 2',3'-cyclic monophosphate

    CAS :
    <p>Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments.<br>AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.</p>
    Formule :C10H12N5O6P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :329.21 g/mol

    Ref: 3D-NA10355

    2mg
    227,00€
    5mg
    439,00€
    10mg
    699,00€
    20mg
    1.080,00€
    50mg
    2.018,00€
  • Adenylyl-3'-5'-guanosine sodium salt

    CAS :
    <p>3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--&gt; 3'--O--(CH2)4--CONH2 + H3PO4</p>
    Formule :C20H24N10O11P·Na
    Degré de pureté :Min. 95%
    Masse moléculaire :634.43 g/mol

    Ref: 3D-NA46044

    1mg
    733,00€
    2mg
    1.275,00€
    5mg
    2.181,00€
    10mg
    3.355,00€
  • 2'-Deoxy-3,4,5,6-tetrahydrouridine

    CAS :
    <p>2'-Deoxy-3,4,5,6-tetrahydrouridine (2DTHR) is a cytidine deaminase inhibitor that is used in vitro to inhibit the production of tumor necrosis factor (TNF). 2DTHR has been shown to be active against hepatocellular carcinoma cells. It is also reactive with tumor tissue and can be eliminated at a rate similar to that of deoxycytidine kinase. This drug binds to the enzyme target and inhibits its activity by increasing enzyme levels, which causes cell death. 2DTHR inhibits TNF production in tumor tissue by binding to cytidine deaminase and preventing conversion of cytidine into uracil. This drug has been shown to cause tumor inhibition in vitro.</p>
    Formule :C9H16N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :232.23 g/mol

    Ref: 3D-ND176541

    1mg
    238,00€
    2mg
    357,00€
    5mg
    710,00€
    10mg
    1.035,00€
    25mg
    1.419,00€
  • ent-abacavir

    CAS :
    <p>Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.</p>
    Formule :C14H18N6O
    Degré de pureté :Min. 95%
    Masse moléculaire :286.33 g/mol

    Ref: 3D-NE16540

    1mg
    410,00€
    2mg
    607,00€
    5mg
    978,00€
    10mg
    1.735,00€
    25mg
    2.957,00€
  • Uridine diphosphate choline (UDPC) sodium

    CAS :
    <p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>
    Formule :C14H25N3O12P2•Na
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :512.3 g/mol

    Ref: 3D-NU182602

    10mg
    1.074,00€
    25mg
    2.033,00€
    50mg
    3.253,00€
    100mg
    5.286,00€
    250mg
    9.294,00€
  • N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution

    CAS :
    <p>N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.</p>
    Formule :C17H22N5O13P3·xNa
    Degré de pureté :Min. 95%
    Couleur et forme :Colorless Powder
    Masse moléculaire :597.3 g/mol

    Ref: 3D-NB45917

    1mg
    390,00€
    2mg
    602,00€
    5mg
    1.102,00€
    10mg
    1.653,00€
    20mg
    2.952,00€
  • Stearoyl coenzyme A free acid hydrate

    CAS :
    <p>Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).</p>
    Formule :C39H70N7O17P3S•H2O
    Degré de pureté :Min. 92 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :1,052.01 g/mol

    Ref: 3D-NS47205

    5mg
    323,00€
    10mg
    416,00€
    25mg
    733,00€
    50mg
    1.171,00€
    100mg
    1.861,00€
  • 2-Fluoroadenosine

    CAS :
    <p>2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. This property may be due to its structural and conformational properties, which are different from those of adenosine. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. It has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. 2-Fluoroadenosine can be used for biochemical and pharmacokinetic studies because it is rapidly metabolized by the liver and excreted in urine.<br>2-Fluoroadenosine can also be used to measure changes in the ratio of adenylate kinase:adenylate kinase reductase (AKAR) in blood plasma.</p>
    Formule :C10H12FN5O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Slightly Yellow Powder
    Masse moléculaire :285.23 g/mol

    Ref: 3D-NF08852

    1g
    263,00€
    2g
    408,00€
    5g
    662,00€
    10g
    1.072,00€
  • 2'-Amino-2'-deoxycytidine

    CAS :
    <p>2'-Amino-2'-deoxycytidine is a modified nucleoside, based on cytidine. In this compound 2'-hydroxyl group has been replaced by an amino group, which can change hydrogen bonding patterns potentially affecting how it interacts with biomolecules.</p>
    Formule :C9H14N4O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :242.24 g/mol

    Ref: 3D-NA02637

    25mg
    361,00€
    50mg
    494,00€
    100mg
    720,00€
    250mg
    985,00€
    500mg
    1.238,00€
  • 2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine

    CAS :
    <p>2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.</p>
    Formule :C9H10FN3O3
    Degré de pureté :Min. 95%
    Masse moléculaire :227.19 g/mol

    Ref: 3D-ND90458

    5mg
    218,00€
    10mg
    355,00€
    25mg
    668,00€
    50mg
    1.030,00€
    100mg
    1.735,00€
  • Malonyl coenzyme A lithium salt - 90%

    CAS :
    <p>Malonyl coenzyme A lithium salt - 90% is a fatty acid that is involved in the biosynthesis of fats. It is also involved in the synthesis of prostaglandins, which are hormone-like substances that have a wide variety of effects on many different tissues. Malonyl coenzyme A lithium salt - 90% may be useful for the treatment of insulin resistance and obesity due to its ability to stimulate glucose uptake by fat cells and increase insulin sensitivity. The following product details are for a supplement:</p>
    Formule :C24H38N7O19P3S·xLi
    Degré de pureté :Min. 95%
    Masse moléculaire :853.58 g/mol

    Ref: 3D-NM47199

    5mg
    478,00€
    10mg
    748,00€
    25mg
    1.085,00€
    50mg
    1.954,00€
    100mg
    3.274,00€
  • 2-Phenylaminoadenosine

    CAS :
    <p>2-Phenylaminoadenosine (2-PA) is a potent and selective inhibitor of the P2Y receptor. 2-PA has been shown to reduce myocardial infarct size in vivo in mice, which may be due to its ability to inhibit the release of dopamine from the brain. In addition, 2-PA binds to LPS receptors on endothelial cells, reducing the production of proinflammatory cytokines and preventing platelet aggregation. 2-PA also inhibits the activation of toll-like receptor 4 (TLR4) in human monocytes, leading to reduced expression of proinflammatory cytokines and increased expression of anti-inflammatory cytokines.<br>2-PA is an agonist that binds with high affinity to P2Y receptors on erythrocytes. This binding results in decreased adenosine triphosphate (ATP) production by adenosine deaminase, which leads to decreased intracellular calcium levels and inhibition of neutroph</p>
    Formule :C16H18N6O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :358.35 g/mol

    Ref: 3D-NP07291

    5mg
    182,00€
  • 2-Chloroadenosine

    CAS :
    <p>2-Chloroinosine is an adenosine receptor agonist; metabolically stable analog of adenosine</p>
    Formule :C10H12ClN5O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :301.69 g/mol

    Ref: 3D-NC06293

    5g
    285,00€
    10g
    401,00€
    25g
    535,00€
    50g
    735,00€
    100g
    1.084,00€
  • 3′-Guanylic acid disodium

    CAS :
    <p>3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.</p>
    Formule :C10H14N5O8P•Na2
    Degré de pureté :Min. 95%
    Masse moléculaire :409.2 g/mol

    Ref: 3D-NG182606

    10mg
    341,00€
    25mg
    607,00€
    50mg
    978,00€
    100mg
    1.518,00€
    250mg
    3.169,00€
  • 5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å


    <p>5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.</p>
    Couleur et forme :Powder

    Ref: 3D-ND11610

    1g
    265,00€
    5g
    663,00€
    10g
    1.052,00€
  • Guanylyl-3',5'-guanosine ammonium salt

    CAS :
    <p>Guanylyl-3',5'-guanosine ammonium salt is a novel antiviral agent that has high antiviral activity against influenza A virus. It is a guanine derivative which has been modified to include an aminopropyl group and an ammonium cation. This compound also acts as an activator for deoxyribonucleosides, nucleotides, and ribonucleosides. Guanylyl-3',5'-guanosine ammonium salt may be used in the manufacture of DNA, RNA, and phosphoramidites. This compound also has anticancer effects by inhibiting the proliferation of tumor cells and inducing apoptosis.</p>
    Formule :C20H25N10O12P·H3N
    Degré de pureté :Min. 95%
    Masse moléculaire :645.48 g/mol

    Ref: 3D-NG11482

    1g
    2.442,00€
    1mg
    666,00€
    2mg
    1.159,00€
    5mg
    1.983,00€
  • 4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester

    CAS :
    <p>Focuses is a chemical compound that does not have any known commercial or industrial uses.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC44293

    1g
    276,00€
    2g
    410,00€
    5g
    607,00€
    250mg
    135,00€
    500mg
    182,00€
  • 5′-O-DMT-LNA N-Bz 5-Me cytidine

    CAS :
    <p>5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.</p>
    Formule :C39H37N3O8
    Degré de pureté :Min. 95%
    Masse moléculaire :675.73 g/mol

    Ref: 3D-ND182844

    1g
    729,00€
    2g
    1.085,00€
    100mg
    291,00€
    250mg
    410,00€
    500mg
    547,00€