Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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2'-Deoxy-L-cytidine
CAS :<p>2'-Deoxy-L-cytidine is a nucleoside that is naturally found in the cells of E. coli K-12. It is an antioxidant compound that prevents lipid peroxidation and scavenges free radicals, which are generated by certain chemical reactions. 2'-Deoxy-L-cytidine has been shown to have antiviral potency in vitro, but its antiviral activity has not been evaluated in vivo. This compound also inhibits the growth of bacteria that are resistant to tetracycline, such as Mycobacterium tuberculosis and Helicobacter pylori. 2'-Deoxy-L-cytidine may cause drug interactions with other medications because it is metabolized by the CYP450 system and inhibits the activity of cytochrome P450 enzymes.</p>Formule :C9H13N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :227.22 g/mol8-Oxoguanosine
CAS :<p>8-Oxoguanosine is an oxidative DNA lesion that has been shown to be a potential biomarker for the detection of cancer cells. 8-Oxoguanosine is produced by a number of pharmacological agents and reactive oxygen species, such as hydrogen peroxide and nitric oxide. It has been shown to bind to DNA duplexes, inhibiting their replication and repair, which may lead to cancer development. The electrochemical detector can detect 8-oxoguanosine at concentrations as low as 1 μM in biological samples.</p>Formule :C10H13N5O6Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :299.24 g/mol3'-Deoxyguanosine
CAS :3'-Deoxyguanosine is a nucleic acid that is involved in the synthesis of polysaccharides and proteins. It has been shown to have an inhibitory effect on the synthesis of collagen, which may be due to its ability to increase hydrogen bonding between the nitrogen atoms and oxygen atoms. 3'-Deoxyguanosine has also been shown to have a protective effect on wheat germ extract, which may be due to its ability to inhibit oxidation reactions. The chemical structure of 3'-deoxyguanosine can be synthesized by reacting deoxyribose with sodium nitrate in the presence of sulfuric acid. This reaction can be monitored using electrochemical impedance spectroscopy (EIS).Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :267.25 g/mol2'-Deoxy-5-fluorocytidine
CAS :<p>2'-Deoxy-5-fluorocytidine is a methyltransferase inhibitor that inhibits the activity of DNA methyltransferases. It has been shown to inhibit the activity of DNA methyltransferases in vitro and in vivo, leading to tumor cell death. 2'-Deoxy-5-fluorocytidine has been shown to target intracellular targets, such as histones and ribosomes, which are involved in cancer development. The toxicity of this drug has been studied extensively and it has been shown to have low toxicity in mice. This drug is not toxic for normal cells or animals when administered at high doses.</p>Formule :C9H12FN3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :245.21 g/mol2',3',5'-Tri-O-acetyl-5-bromouridine
CAS :2',3',5'-Tri-O-acetyl-5-bromouridine is a nucleoside analog of uridine, a basic building block of RNA. It has the addition of a bromine atom and three acetyl groups. 2',3',5'-Tri-O-acetyl-5-bromouridine can be used in researchFormule :C15H17BrN2O9Degré de pureté :Min. 90%Masse moléculaire :449.21 g/mol2'-Deoxy-5'-O-DMT-inosine
CAS :2'-Deoxy-5'-O-DMT-inosine is a chain congener of uridine and cytidine. It is an analog of guanosine, which is found in DNA. 2'-Deoxy-5'-O-DMT-inosine has shown to have cytotoxic effects on the cardiovascular system, as well as inflammatory properties. This drug can also inhibit nitric oxide production and chloride transport. The nitro group in 2'-deoxy-5'-O-DMT-inosine can be removed by ammonolysis or debenzoylation and glycosylation can be added to the molecule with the addition of glucose.Formule :C31H30N4O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :554.61 g/mol3'-O-Methylinosine
CAS :<p>3'-O-Methylinosine is a synthetic nucleoside that inhibits the synthesis of viral DNA and RNA by interacting with the enzyme ribonucleotide reductase. This antiviral agent has been shown to be effective against a wide range of viruses, including human cytomegalovirus, herpes simplex virus type 1, varicella-zoster virus, and influenza A virus. 3'-O-Methylinosine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Formule :C11H14N4O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :282.25 g/mol2-Amino-2'-O-methyladenosine
CAS :<p>2-Amino-2'-O-methyladenosine is a modified nucleoside based on adenosine with a 2-amino group on the base, and a 2'-O-methyl group on the sugar.</p>Formule :C11H16N6O4Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :296.28 g/mol(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine
CAS :<p>(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a nucleoside for a range of applications</p>Formule :C12H14N2O7Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :298.25 g/molGuanosine 2',3'-cyclic monophosphate sodium
CAS :<p>Guanosine 2',3'-cyclic monophosphate sodium is a novel antiviral agent that has been shown to be effective against HIV, herpesviruses, and vaccinia virus. It is an activator of guanosine 3'-5' cyclic monophosphate (cGMP) and can be used as a substitute for the nucleoside guanosine 5'-triphosphate (GTP). Guanosine 2',3'-cyclic monophosphate sodium inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase. This drug also has anticancer properties, which may be due to its ability to inhibit the production of tumor necrosis factor-α (TNF-α) in mice with lung cancer.</p>Formule :C10H11N5NaO7PDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :367.19 g/molAdenosine 5'-diphosphate
CAS :<p>Adenosine 5'-diphosphate (ADP) is a nucleoside that is an important component of the cell's energy pathways. ADP plays a role in platelet activation and nitrate reductase, which are enzymes that maintain the integrity of bacterial DNA. Adenosine 5'-diphosphate also has been shown to inhibit neural cell injury and protein oxidation.</p>Formule :C10H15N5O10P2Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :427.2 g/mol8-Bromo-2'-deoxyadenosine
CAS :8-Bromo-2'-deoxyadenosine (8-BrdA) is a reactive chemical that can be used in the study of DNA. It is used to measure the kinetics of oxidative dna damage and to study glycosidic bond cleavage reactions. 8-BrdA reacts with eosinophil peroxidase to yield an oxidant, which can then react with dna duplexes. This reaction has been shown to affect both intramolecular and intermolecular hydrogen bonds. 8-BrdA also has been shown to induce cell death in vitro by apoptosis.Formule :C10H12BrN5O3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :330.14 g/mol3'-Deoxy-3'-fluorothymidine
CAS :3'-Deoxy-3'-fluorothymidine is a nucleoside analog that is used to diagnose and treat cancer. It is a prodrug that is metabolized intracellularly by deoxycytidine kinase to the 3'-deoxy-3'-fluoro derivative of thymidine, which competes with natural thymidine for incorporation into DNA. Uptake of 18F-flouride (18F-FDG) in tumor cells has been shown to be proportional to the rate constant (k) of cellular uptake. This process can be quantified using positron emission tomography imaging. The cell cycle inhibitor activity of 3'-deoxy-3'-fluorothymidine has also been demonstrated in vitro and in vivo, inhibiting the proliferation of tumor cells and normal cells in culture, respectively.Formule :C10H13FN2O4Degré de pureté :Min. 97 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :244.22 g/mol5-Chloro-2-pyridinecarboxylic acid methyl ester
CAS :<p>5-Chloro-2-pyridinecarboxylic acid methyl ester is a monophosphate nucleoside that can be used in the synthesis of DNA and RNA. It is also an antiviral, anticancer, and anticoagulant agent. 5-Chloro-2-pyridinecarboxylic acid methyl ester has been shown to inhibit DNA replication and transcription by inhibiting the activity of enzymes involved in these processes. It can be used as a building block for the synthesis of DNA and RNA. The purity of this product is high, with no detectable impurities at levels above 0.1%.</p>Formule :C7H6ClNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :171.58 g/molGuanylyl-3'-5'-cytidine ammonium salt
CAS :<p>Guanylyl-3'-5'-cytidine ammonium salt is a nucleoside that is classified as a diphosphate. It has high quality and novel, anticancer and cytotoxic effects. Guanylyl-3'-5'-cytidine ammonium salt is synthesized from guanosine monophosphate (GMP) and cytidine monophosphate (CMP).</p>Formule :C19H25N8O12P·NH3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :605.46 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine
CAS :9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is a synthetic nucleoside that can be phosphorylated to form 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine 5'-triphosphate. This compound has been shown to have antitumor and antiviral activities. It inhibits DNA synthesis by inhibiting the activity of DNA polymerase and RNA polymerase, which are enzymes necessary for the replication of cellular DNA and RNA, respectively. 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is high quality, novel, and CAS No. 98983-40-5.Formule :C10H11FN4O4Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :270.22 g/molIsocytidine
CAS :<p>Isocytidine, also known as 2-amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone, have broad antitumor activity targeting indolent lymphoid malignancies.</p>Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :243.22 g/molN7-Methylguanosine
CAS :<p>N-7-Methylguanosine is a nucleotide that has potent anti-viral activity. It inhibits viral replication by binding to the effector proteins of a virus and preventing translation, transcriptional regulation, and other biochemical processes. N7-Methylguanosine also binds to the x-ray crystal structures of the viral genome and blocks the binding of RNA polymerase to DNA. This drug can be used as an antiviral agent for the treatment of HIV infection and hepatitis B infection. N7-Methylguanosine is not active against some viruses such as herpes simplex virus type 1 or 2, influenza virus type A/B, or rhinovirus type 2.<br>N7-Methylguanosine has been shown to have an effect on body mass index in humans by reducing weight gain in patients with metabolic syndrome. It also has an enzyme form that can be used for therapeutic use in human serum.</p>Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :297.27 g/molOrotidine 5'-monophosphate trisodium salt
CAS :<p>Ribonuclesides is a novel nucleoside that contains the 2'-deoxyribose phosphate moiety. It is an anticancer drug that inhibits DNA synthesis and blocks viral replication. Ribonucleosides are phosphoramidites and can be used for the synthesis of DNA or RNA, which are important for cellular metabolism. Ribonucleosides also have antiviral properties and can inhibit protein synthesis by blocking the enzyme ribonucleotide reductase.</p>Formule :C10H10N2O11PNa3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :434.14 g/mol2'-Deoxy-N6-(2-hydroxyethyl)adenosine
CAS :2'-Deoxy-N6-(2-hydroxyethyl)adenosine is a synthetic nucleoside that is used as a building block for the chemical synthesis of oligonucleotides. It is also an antiviral agent and has been shown to have anticancer properties. 2'-Deoxy-N6-(2-hydroxyethyl)adenosine is used in the manufacture of phosphoramidites, deoxyribonucleosides, and ribonucleosides. This product can be synthesized at high purity and quality, with CAS No. 137058-94-7.Formule :C12H17N5O4Degré de pureté :Min. 95%Masse moléculaire :295.29 g/mol
