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Nucléotides

Nucléotides

Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.

Sous-catégories appartenant à la catégorie "Nucléotides"

2634 produits trouvés pour "Nucléotides"

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  • 2'-Deoxypseudouridine

    CAS :
    <p>2'-Deoxypseudouridine is a nucleotide that is synthesized from the sugar ribose-5-phosphate and uracil. It is used in biological systems to transfer phosphate groups, which are vital to the metabolism of energy. 2'-Deoxypseudouridine also binds to DNA, forming stable complexes with enzymes and other molecules. This nucleotide is often found in oligodeoxynucleotides, which are used as antiviral agents. 2'-Deoxypseudouridine has been shown to have antimicrobial activity against various viruses, including hepatitis B virus (HBV). It has also been tested for its ability to inhibit replication of HIV-1 in vitro. The enzyme glycosylase catalyzes the reaction of 2'-deoxypseudouridine with water, producing an unstable intermediate that spontaneously converts into dUMP and pyrophosphate.</p>
    Formule :C9H12N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :228.21 g/mol

    Ref: 3D-ND06413

    5mg
    208,00€
    10mg
    361,00€
    25mg
    599,00€
  • 5'-O-Benzoyl-2'-deoxyinosine


    <p>5'-O-Benzoyl-2'-deoxyinosine is an antiviral agent that inhibits the replication of certain viruses. It is a nucleoside analog that contains a benzoyl group at the 5' position and a 2'-deoxyribose sugar moiety. It has been shown to inhibit the growth of cancer cells in vitro and to produce cytotoxic effects on human lymphocytes. This compound is synthesized by reacting an appropriate ribonucleotide with phosphoramidite reagents, which are used as starting materials for DNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB145906

    50mg
    135,00€
    100mg
    156,00€
    250mg
    283,00€
    500mg
    483,00€
  • 7-Cyano-7-deaza-2'-deoxyadenosine

    CAS :
    <p>7-Cyano-7-deaza-2'-deoxyadenosine is a nucleoside analog that inhibits the growth of virus by competing with deoxyadenosine for incorporation into DNA and RNA. 7-Cyano-7-deaza-2'-deoxyadenosine also stabilizes dna duplexes and prevents them from breaking down. It has been shown to be effective against herpes simplex virus, which causes painful blisters on the skin or genitals. This drug has been used in clinical trials as an antiviral agent. 7-Cyano-7-deaza-2'-deoxyadenosine is synthesized from 2',3'-didehydrocytidine under the following conditions:</p>
    Formule :C12H13N5O3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :275.26 g/mol

    Ref: 3D-NC144684

    1mg
    198,00€
    2mg
    305,00€
  • Uridine-5-oxyacetic acid

    CAS :
    <p>Uridine-5-oxyacetic acid is a molecule that is synthesized from uridine and 5-oxo-4-pyrone. It is an intermediate in the synthesis of pyrimidine nucleotides, which are important for DNA replication, repair, and transcription. Uridine-5-oxyacetic acid has been shown to form stable complexes with subtilisin. These complexes have been determined by X-ray crystallography to be glycosidic bond between the uridine and the enzyme. The enzymatic activity of subtilisin can be inhibited by these complexes, which may lead to frameshifting during bacterial translation. This inhibition leads to a less efficient protein synthesis process and a decrease in the production of gene products.</p>
    Formule :C11H14N2O9
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :318.24 g/mol

    Ref: 3D-NU158553

    1mg
    294,00€
    2mg
    442,00€
    5mg
    745,00€
    10mg
    1.141,00€
    25mg
    2.051,00€
  • Malonyl coenzyme A lithium salt - 97%

    CAS :
    <p>Malonyl-CoA is a metabolite that regulates the storage of fat and the production of energy in adipose tissue. Malonyl coenzyme A lithium salt is a fatty acid, which has been shown to reduce insulin resistance in response to diet in mice. It also has an anti-obesity effect by lowering body weight and reducing fat mass accumulation. The mechanism for this is not fully understood but may involve regulation of tnf-α activity and adipocyte hypertrophy.</p>
    Formule :C24H37N7O19P3S·xLi
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :852.57 g/mol

    Ref: 3D-NM59495

    5mg
    254,00€
    10mg
    439,00€
    25mg
    764,00€
    50mg
    1.288,00€
    100mg
    2.213,00€
  • 3'-Deoxyuridine

    CAS :
    <p>3'-Deoxyuridine is a synthetic antibiotic that is used in the treatment of viral infections, such as hepatitis B and C, and HIV. 3'-Deoxyuridine competitively inhibits the synthesis of RNA by binding to the enzyme RNA polymerase. This drug also has antiviral activity against the human cytomegalovirus (CMV) and Hepatitis C virus (HCV). 3'-Deoxyuridine is synthesized from uracil in an organic solvent, trifluoroacetic acid, at low temperatures. The incorporation of deoxynucleoside triphosphates into DNA occurs after cleavage of the terminal phosphate group by water vapor.</p>
    Formule :C9H12N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :228.21 g/mol

    Ref: 3D-ND05963

    25mg
    305,00€
    50mg
    430,00€
    100mg
    679,00€
    250mg
    1.062,00€
    500mg
    1.366,00€
  • 2',3'-Dideoxyguanosine

    CAS :
    <p>2',3'-Dideoxyguanosine is a nucleoside for use in research applications</p>
    Formule :C10H13N5O3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :251.25 g/mol

    Ref: 3D-ND04069

    1g
    1.078,00€
    2g
    1.643,00€
    100mg
    282,00€
    250mg
    472,00€
    500mg
    717,00€
  • 4'-Thioadenosine

    CAS :
    <p>4'-Thioadenosine is a nucleoside that has been shown to inhibit the growth of leukemia cells by binding to adenosine receptors. It is also able to inhibit the activity of the mammalian phosphodiesterase PDE4, which is responsible for hydrolyzing cAMP. The cellular effects of 4'-thioadenosine can be seen in HL-60 human cells, and this drug has also shown promising results in animal models of kidney fibrosis and liver cirrhosis. 4'-Thioadenosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>
    Formule :C10H13N5O3S
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :283.31 g/mol

    Ref: 3D-NT162617

    1g
    7.626,00€
    1mg
    477,00€
    5mg
    1.137,00€
    10mg
    1.667,00€
    25mg
    3.137,00€
  • Thymidylyl-3'-5'-thymidine ammonium

    CAS :
    <p>Thymidylyl-3'-5'-thymidine ammonium is a cytotoxic drug that belongs to the class of thymidylate synthase inhibitors. It inhibits enzymes responsible for DNA synthesis and repair by binding to the active site of these enzymes and forming covalent bonds with amino acid residues. Thymidylyl-3'-5'-thymidine ammonium can be used as a therapeutic agent in radiation therapy because it is more effective than other drugs at inhibiting cell growth. Thymidylyl-3'-5'-thymidine ammonium has been shown to inhibit the activity of carcinogenic compounds, such as benzo[a]pyrene and benzene, in a model system. Thymidylyl-3'-5'-thymidine ammonium also has the ability to form covalent bonds with dna duplexes and change their conformational properties.</p>
    Formule :C20H27N4O12P·NH3
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :563.45 g/mol

    Ref: 3D-NT07991

    2mg
    232,00€
    5mg
    402,00€
    10mg
    530,00€
    25mg
    930,00€
    50mg
    1.299,00€
  • N2-DMF-5'-O-DMT-2'-O-methylguanosine

    CAS :
    <p>N2-DMF-5'-O-DMT-2'-O-methylguanosine is a novel nucleoside analog that has antiviral, anticancer and immunomodulating properties. It is synthesized from 2′,3′-dideoxyadenosine 5′-monophosphate by the condensation of 2,6-dimethylaniline with methylguanosine 5′-monophosphate and 5,6-dimethylaniline. The modification of the guanine base in N2-DMF-5'-O-DMT-2'-O-methylguanosine to an O6 -methyl group results in increased affinity for the ribonucleotide reductase enzyme (RNR) and inhibition of DNA synthesis.</p>
    Formule :C35H38N6O7
    Degré de pureté :Min. 95%
    Masse moléculaire :654.71 g/mol

    Ref: 3D-ND08425

    1g
    349,00€
    2g
    454,00€
    100mg
    134,00€
    250mg
    188,00€
    500mg
    272,00€
  • 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one

    CAS :
    <p>6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a novel nucleoside that has been shown to have anticancer and antiviral properties. In vitro studies have shown the compound to activate both DNA and RNA synthesis in cells. The compound also inhibits the replication of HIV viruses. 6-(β-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is synthesized from ribonucleosides or deoxyribonucleosides through phosphoramidite chemistry. This product is available in high purity and high quality.</p>
    Formule :C11H15N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :269.25 g/mol

    Ref: 3D-ND145587

    10mg
    277,00€
    20mg
    416,00€
    50mg
    679,00€
    100mg
    1.023,00€
    250mg
    2.011,00€
  • Guanosine 5'-diphosphate disodium salt

    CAS :
    <p>Guanosine 5'-diphosphate (GDP) disodium salt is a nucleoside dipsphate and a pyruvate kinase substrate, which converts GDP to GTP.</p>
    Formule :C10H13N5O11P2·2Na
    Degré de pureté :Min. 90 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :487.17 g/mol

    Ref: 3D-NG09782

    5g
    382,00€
    10g
    573,00€
    25g
    1.041,00€
    50g
    1.620,00€
    100g
    2.483,00€
  • 5-Fluorouridine

    CAS :
    <p>5-Fluorouridine, also called 1-(b-D-ribofuranosyl)-5-fluorouracil and 5-fluoro-D-uridine (FUrd), is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil, a drug used to treat a variety of cancers, on the market with the trade name Adrucil. Prodrugs of 5-fluorouridine have been investigated for anti-tumour properties in their own right and are close structural analogues of 5'-deoxy-5-fluorouridine, a cytostatic agent in chemotherapy.</p>
    Formule :C9H11FN2O6
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :262.2 g/mol

    Ref: 3D-NF04076

    10g
    280,00€
    25g
    472,00€
    50g
    701,00€
    100g
    1.085,00€
  • 2'-Deoxycytidine

    CAS :
    <p>2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. It has been shown to have potent antitumor activity against solid tumours and may be useful for the treatment of leukemic mice. This compound has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion, which may make it a good candidate as an anticancer drug.</p>
    Formule :C9H13N3O4
    Degré de pureté :Min. 99 Area-%
    Couleur et forme :Powder
    Masse moléculaire :227.22 g/mol

    Ref: 3D-ND06286

    2g
    187,00€
    5g
    296,00€
    10g
    412,00€
    25g
    679,00€
    50g
    953,00€
  • 1-(3'-5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-α-L-arabinofuranosyl)thymine


    <p>1-(3`-5`-Di-O-benzoyl-2`-deoxy-2`-fluoro-alpha-L-arabinofuranosyl)thymine is a nucleoside analog with modifications that influence its biological activity. It is made up of a thymine base, benzoyl groups that protect hydroxyl functionalities during chemical synthesis and a α-L-linkage, which impacts its biological interactions compared to β-L-nucleosides. This molecule also contains the sugar 2'-Deoxy-2'-fluoro-α-L-arabinofuranose which has a L-arabinose configuration, an α-Anomeric linkage and a 2'-Fluoro substitution. The latter modification has the potential to increase the molecule's metabolic stability and resistance to enzymatic degradation</p>
    Formule :C24H21FN2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :484.89 g/mol

    Ref: 3D-ND182974

    1g
    286,00€
    2g
    457,00€
    250mg
    134,00€
    500mg
    184,00€
  • Thymidine

    CAS :
    <p>Thymidine is a nucleoside that is found in cells and is involved in the synthesis of DNA. Thymidine has been shown to inhibit the growth of tumor cells through apoptosis. In addition, thymidine can be used for the treatment of bowel disease by reducing inflammation and increasing the production of mucin. The mechanism by which thymidine exerts its effects on tumor cells is not well understood, but it may involve interactions with dna binding activity and enzyme activities.</p>
    Formule :C10H14N2O5
    Degré de pureté :Min. 99 Area-%
    Masse moléculaire :242.23 g/mol

    Ref: 3D-Q-201829

    1kg
    À demander
    5kg
    À demander
    250g
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    500g
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    2500g
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  • 2'-Deoxy-6-thioguanosine

    CAS :
    <p>2'-Deoxy-6-thioguanosine is a purine nucleoside analog that inhibits the activation of transcription factors such as nuclear factor kappa-B (NF-κB) and activator protein 1 (AP-1). It also inhibits the synthesis of proinflammatory cytokines, such as IL-1β, IL-6, and TNFα. The matrix effect is an important factor in the prevention of tumor progression. 2'-Deoxy-6-thioguanosine has been shown to inhibit cell proliferation and induce apoptosis in squamous cell carcinoma cells by modulating the expression of HLA class II molecules on tumors. It also prevents invasion by blocking matrix metalloproteinase activity. 2'-Deoxy-6-thioguanosine has been found to be effective against bowel diseases such as ulcerative colitis and Crohn's disease, as well as infectious diseases such as HIV/AIDS.</p>
    Formule :C10H13N5O3S
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :283.31 g/mol

    Ref: 3D-ND08563

    25mg
    183,00€
    50mg
    305,00€
    100mg
    477,00€
    250mg
    723,00€
    500mg
    1.136,00€
  • 5'-O-DMT-a-thymidine


    <p>5'-O-DMT-a-thymidine is a modified nucleoside that is used in the synthesis of DNA and RNA. This product is a high quality and pure monophosphate, which has been modified to reduce its potential for activation by phosphatases. It is suitable for use in anticancer drugs and antiviral agents.</p>
    Formule :C31H32N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :544.6 g/mol

    Ref: 3D-ND146115

    1g
    229,00€
    2g
    403,00€
    250mg
    134,00€
    500mg
    159,00€
  • 2'-Deoxy-L-cytidine

    CAS :
    <p>2'-Deoxy-L-cytidine is a nucleoside that is naturally found in the cells of E. coli K-12. It is an antioxidant compound that prevents lipid peroxidation and scavenges free radicals, which are generated by certain chemical reactions. 2'-Deoxy-L-cytidine has been shown to have antiviral potency in vitro, but its antiviral activity has not been evaluated in vivo. This compound also inhibits the growth of bacteria that are resistant to tetracycline, such as Mycobacterium tuberculosis and Helicobacter pylori. 2'-Deoxy-L-cytidine may cause drug interactions with other medications because it is metabolized by the CYP450 system and inhibits the activity of cytochrome P450 enzymes.</p>
    Formule :C9H13N3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :227.22 g/mol

    Ref: 3D-ND05747

    1g
    1.008,00€
    2g
    1.819,00€
    100mg
    260,00€
    200mg
    368,00€
    500mg
    603,00€
  • 8-Oxoguanosine

    CAS :
    <p>8-Oxoguanosine is an oxidative DNA lesion that has been shown to be a potential biomarker for the detection of cancer cells. 8-Oxoguanosine is produced by a number of pharmacological agents and reactive oxygen species, such as hydrogen peroxide and nitric oxide. It has been shown to bind to DNA duplexes, inhibiting their replication and repair, which may lead to cancer development. The electrochemical detector can detect 8-oxoguanosine at concentrations as low as 1 μM in biological samples.</p>
    Formule :C10H13N5O6
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :299.24 g/mol

    Ref: 3D-NO05772

    10mg
    264,00€
    25mg
    429,00€
    50mg
    637,00€
    100mg
    863,00€
    250mg
    1.707,00€
  • 3'-Deoxyguanosine

    CAS :
    <p>3'-Deoxyguanosine is a nucleic acid that is involved in the synthesis of polysaccharides and proteins. It has been shown to have an inhibitory effect on the synthesis of collagen, which may be due to its ability to increase hydrogen bonding between the nitrogen atoms and oxygen atoms. 3'-Deoxyguanosine has also been shown to have a protective effect on wheat germ extract, which may be due to its ability to inhibit oxidation reactions. The chemical structure of 3'-deoxyguanosine can be synthesized by reacting deoxyribose with sodium nitrate in the presence of sulfuric acid. This reaction can be monitored using electrochemical impedance spectroscopy (EIS).</p>
    Formule :C10H13N5O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :267.25 g/mol

    Ref: 3D-ND06319

    100mg
    316,00€
    250mg
    469,00€
    500mg
    725,00€
  • 2'-Deoxy-5-fluorocytidine

    CAS :
    <p>2'-Deoxy-5-fluorocytidine is a methyltransferase inhibitor that inhibits the activity of DNA methyltransferases. It has been shown to inhibit the activity of DNA methyltransferases in vitro and in vivo, leading to tumor cell death. 2'-Deoxy-5-fluorocytidine has been shown to target intracellular targets, such as histones and ribosomes, which are involved in cancer development. The toxicity of this drug has been studied extensively and it has been shown to have low toxicity in mice. This drug is not toxic for normal cells or animals when administered at high doses.</p>
    Formule :C9H12FN3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :245.21 g/mol

    Ref: 3D-ND10199

    1g
    430,00€
    2g
    550,00€
    5g
    1.014,00€
    500mg
    272,00€
  • 2',3',5'-Tri-O-acetyl-5-bromouridine

    CAS :
    <p>2',3',5'-Tri-O-acetyl-5-bromouridine is a nucleoside analog of uridine, a basic building block of RNA. It has the addition of a bromine atom and three acetyl groups. 2',3',5'-Tri-O-acetyl-5-bromouridine can be used in research</p>
    Formule :C15H17BrN2O9
    Degré de pureté :Min. 90%
    Masse moléculaire :449.21 g/mol

    Ref: 3D-NT15543

    1g
    305,00€
    2g
    477,00€
    5g
    645,00€
    10g
    1.045,00€
    25g
    1.743,00€
  • 2'-Deoxy-5'-O-DMT-inosine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-inosine is a chain congener of uridine and cytidine. It is an analog of guanosine, which is found in DNA. 2'-Deoxy-5'-O-DMT-inosine has shown to have cytotoxic effects on the cardiovascular system, as well as inflammatory properties. This drug can also inhibit nitric oxide production and chloride transport. The nitro group in 2'-deoxy-5'-O-DMT-inosine can be removed by ammonolysis or debenzoylation and glycosylation can be added to the molecule with the addition of glucose.</p>
    Formule :C31H30N4O6
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :554.61 g/mol

    Ref: 3D-ND08417

    1g
    135,00€
    2g
    143,00€
    5g
    229,00€
    10g
    356,00€
    25g
    637,00€
  • 3'-O-Methylinosine

    CAS :
    <p>3'-O-Methylinosine is a synthetic nucleoside that inhibits the synthesis of viral DNA and RNA by interacting with the enzyme ribonucleotide reductase. This antiviral agent has been shown to be effective against a wide range of viruses, including human cytomegalovirus, herpes simplex virus type 1, varicella-zoster virus, and influenza A virus. 3'-O-Methylinosine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>
    Formule :C11H14N4O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :282.25 g/mol

    Ref: 3D-NM01973

    25mg
    478,00€
    50mg
    668,00€
    100mg
    863,00€
  • 2-Amino-2'-O-methyladenosine

    CAS :
    <p>2-Amino-2'-O-methyladenosine is a modified nucleoside based on adenosine with a 2-amino group on the base, and a 2'-O-methyl group on the sugar.</p>
    Formule :C11H16N6O4
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :296.28 g/mol

    Ref: 3D-NA06394

    1g
    444,00€
    2g
    729,00€
    5g
    921,00€
    10g
    1.085,00€
  • (E)-5-(2-Carboxyvinyl)-2'-deoxyuridine

    CAS :
    <p>(E)-5-(2-Carboxyvinyl)-2'-deoxyuridine is a nucleoside for a range of applications</p>
    Formule :C12H14N2O7
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :298.25 g/mol

    Ref: 3D-NC08239

    1g
    550,00€
    2g
    815,00€
    5g
    1.120,00€
    250mg
    268,00€
    500mg
    410,00€
  • Guanosine 2',3'-cyclic monophosphate sodium

    CAS :
    <p>Guanosine 2',3'-cyclic monophosphate sodium is a novel antiviral agent that has been shown to be effective against HIV, herpesviruses, and vaccinia virus. It is an activator of guanosine 3'-5' cyclic monophosphate (cGMP) and can be used as a substitute for the nucleoside guanosine 5'-triphosphate (GTP). Guanosine 2',3'-cyclic monophosphate sodium inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase and DNA polymerase. This drug also has anticancer properties, which may be due to its ability to inhibit the production of tumor necrosis factor-α (TNF-α) in mice with lung cancer.</p>
    Formule :C10H11N5NaO7P
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :Powder
    Masse moléculaire :367.19 g/mol

    Ref: 3D-NG145480

    10mg
    348,00€
    25mg
    592,00€
    50mg
    915,00€
    100mg
    1.534,00€
    250mg
    3.268,00€
  • Adenosine 5'-diphosphate

    CAS :
    <p>Adenosine 5'-diphosphate (ADP) is a nucleoside that is an important component of the cell's energy pathways. ADP plays a role in platelet activation and nitrate reductase, which are enzymes that maintain the integrity of bacterial DNA. Adenosine 5'-diphosphate also has been shown to inhibit neural cell injury and protein oxidation.</p>
    Formule :C10H15N5O10P2
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :427.2 g/mol

    Ref: 3D-NA10698

    10g
    308,00€
    25g
    483,00€
    50g
    692,00€
    100g
    1.018,00€
    250g
    2.091,00€
  • 8-Bromo-2'-deoxyadenosine

    CAS :
    <p>8-Bromo-2'-deoxyadenosine (8-BrdA) is a reactive chemical that can be used in the study of DNA. It is used to measure the kinetics of oxidative dna damage and to study glycosidic bond cleavage reactions. 8-BrdA reacts with eosinophil peroxidase to yield an oxidant, which can then react with dna duplexes. This reaction has been shown to affect both intramolecular and intermolecular hydrogen bonds. 8-BrdA also has been shown to induce cell death in vitro by apoptosis.</p>
    Formule :C10H12BrN5O3
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :330.14 g/mol

    Ref: 3D-NB05283

    1g
    329,00€
    2g
    478,00€
    5g
    1.019,00€
    10g
    1.707,00€
    500mg
    179,00€
  • 3'-Deoxy-3'-fluorothymidine

    CAS :
    <p>3'-Deoxy-3'-fluorothymidine is a nucleoside analog that is used to diagnose and treat cancer. It is a prodrug that is metabolized intracellularly by deoxycytidine kinase to the 3'-deoxy-3'-fluoro derivative of thymidine, which competes with natural thymidine for incorporation into DNA. Uptake of 18F-flouride (18F-FDG) in tumor cells has been shown to be proportional to the rate constant (k) of cellular uptake. This process can be quantified using positron emission tomography imaging. The cell cycle inhibitor activity of 3'-deoxy-3'-fluorothymidine has also been demonstrated in vitro and in vivo, inhibiting the proliferation of tumor cells and normal cells in culture, respectively.</p>
    Formule :C10H13FN2O4
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :244.22 g/mol

    Ref: 3D-ND02399

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    5g
    2.286,00€
    250mg
    373,00€
    500mg
    550,00€
  • 5-Chloro-2-pyridinecarboxylic acid methyl ester

    CAS :
    <p>5-Chloro-2-pyridinecarboxylic acid methyl ester is a monophosphate nucleoside that can be used in the synthesis of DNA and RNA. It is also an antiviral, anticancer, and anticoagulant agent. 5-Chloro-2-pyridinecarboxylic acid methyl ester has been shown to inhibit DNA replication and transcription by inhibiting the activity of enzymes involved in these processes. It can be used as a building block for the synthesis of DNA and RNA. The purity of this product is high, with no detectable impurities at levels above 0.1%.</p>
    Formule :C7H6ClNO2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :171.58 g/mol

    Ref: 3D-NC66914

    2g
    135,00€
    5g
    157,00€
    10g
    244,00€
  • Guanylyl-3'-5'-cytidine ammonium salt

    CAS :
    <p>Guanylyl-3'-5'-cytidine ammonium salt is a nucleoside that is classified as a diphosphate. It has high quality and novel, anticancer and cytotoxic effects. Guanylyl-3'-5'-cytidine ammonium salt is synthesized from guanosine monophosphate (GMP) and cytidine monophosphate (CMP).</p>
    Formule :C19H25N8O12P·NH3
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :605.46 g/mol

    Ref: 3D-NG07984

    1mg
    300,00€
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    467,00€
  • 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine

    CAS :
    <p>9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is a synthetic nucleoside that can be phosphorylated to form 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine 5'-triphosphate. This compound has been shown to have antitumor and antiviral activities. It inhibits DNA synthesis by inhibiting the activity of DNA polymerase and RNA polymerase, which are enzymes necessary for the replication of cellular DNA and RNA, respectively. 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)hypoxantine is high quality, novel, and CAS No. 98983-40-5.</p>
    Formule :C10H11FN4O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :270.22 g/mol

    Ref: 3D-ND09525

    1g
    1.302,00€
    2g
    2.286,00€
    100mg
    323,00€
    250mg
    487,00€
    500mg
    764,00€
  • Isocytidine

    CAS :
    <p>Isocytidine, also known as 2-amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone, have broad antitumor activity targeting indolent lymphoid malignancies.</p>
    Formule :C9H13N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :243.22 g/mol

    Ref: 3D-NI24672

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    463,00€
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    799,00€
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    1.368,00€
    250mg
    2.421,00€
  • N7-Methylguanosine

    CAS :
    <p>N-7-Methylguanosine is a nucleotide that has potent anti-viral activity. It inhibits viral replication by binding to the effector proteins of a virus and preventing translation, transcriptional regulation, and other biochemical processes. N7-Methylguanosine also binds to the x-ray crystal structures of the viral genome and blocks the binding of RNA polymerase to DNA. This drug can be used as an antiviral agent for the treatment of HIV infection and hepatitis B infection. N7-Methylguanosine is not active against some viruses such as herpes simplex virus type 1 or 2, influenza virus type A/B, or rhinovirus type 2.<br>N7-Methylguanosine has been shown to have an effect on body mass index in humans by reducing weight gain in patients with metabolic syndrome. It also has an enzyme form that can be used for therapeutic use in human serum.</p>
    Formule :C11H15N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :297.27 g/mol

    Ref: 3D-NM08037

    1g
    1.030,00€
    2g
    1.814,00€
    5g
    2.962,00€
    250mg
    386,00€
    500mg
    615,00€
  • Orotidine 5'-monophosphate trisodium salt

    CAS :
    <p>Ribonuclesides is a novel nucleoside that contains the 2'-deoxyribose phosphate moiety. It is an anticancer drug that inhibits DNA synthesis and blocks viral replication. Ribonucleosides are phosphoramidites and can be used for the synthesis of DNA or RNA, which are important for cellular metabolism. Ribonucleosides also have antiviral properties and can inhibit protein synthesis by blocking the enzyme ribonucleotide reductase.</p>
    Formule :C10H10N2O11PNa3
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :434.14 g/mol

    Ref: 3D-NO71879

    1mg
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    2mg
    543,00€
    5mg
    965,00€
    10mg
    1.440,00€
    25mg
    2.694,00€
  • 2'-Deoxy-N6-(2-hydroxyethyl)adenosine

    CAS :
    <p>2'-Deoxy-N6-(2-hydroxyethyl)adenosine is a synthetic nucleoside that is used as a building block for the chemical synthesis of oligonucleotides. It is also an antiviral agent and has been shown to have anticancer properties. 2'-Deoxy-N6-(2-hydroxyethyl)adenosine is used in the manufacture of phosphoramidites, deoxyribonucleosides, and ribonucleosides. This product can be synthesized at high purity and quality, with CAS No. 137058-94-7.</p>
    Formule :C12H17N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :295.29 g/mol

    Ref: 3D-ND16751

    5mg
    222,00€
    10mg
    333,00€
    25mg
    617,00€
    50mg
    936,00€
    100mg
    1.310,00€
  • 2'-Deoxy-2'-fluorouridine

    CAS :
    <p>2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA.</p>
    Formule :C9H11FN2O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :246.2 g/mol

    Ref: 3D-ND06544

    25g
    458,00€
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    798,00€
    100g
    1.406,00€
    250g
    3.037,00€
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    4.344,00€
  • 2'-O-Methylguanosine-5'-triphosphate sodium salt - 100mM aqueous solution

    CAS :
    <p>2'-O-Methylguanosine-5'-triphosphate sodium salt is a nucleotide that is synthesized by the phosphorylation of guanosine at the 5' position. It has been shown to have significant activation of cardiac protein synthesis and translation. This nucleotide has also been shown to stabilize RNA in vitro, which may be due to its ability to activate adenylate cyclase activity. 2'-O-Methylguanosine-5'-triphosphate sodium salt is a potent inhibitor of hepatitis B virus replication, but does not inhibit the replication of other viruses.</p>
    Formule :C10H18N3O14P3·Na
    Degré de pureté :Min. 95%
    Couleur et forme :Clear Liquid
    Masse moléculaire :520.17 g/mol

    Ref: 3D-NM157274

    5mg
    476,00€
    10mg
    722,00€
    25mg
    1.443,00€
    50mg
    2.556,00€
    2500µg
    282,00€
  • S-(4-Nitrobenzyl)-6-thioinosine

    CAS :
    <p>S-(4-Nitrobenzyl)-6-thioinosine (SBT) is a nucleoside with biochemical properties that are similar to those of adenosine. SBT is an equilibrative nucleoside, which means that it can bind to both DNA and RNA. It has been shown to be effective in inhibiting the growth of cancer cells in vitro by binding to DNA. SBT binds to the purine nucleotide transporter and prevents the uptake of uridine, adenosine, and other nucleosides into the cell. This process leads to a decrease in intracellular concentrations of these nucleosides. SBT also binds to divalent metal ions such as copper or zinc, which may affect its activity on cancer cells.</p>
    Formule :C17H17N5O6S
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :419.41 g/mol

    Ref: 3D-NN09410

    1g
    1.216,00€
    2g
    2.141,00€
    100mg
    226,00€
    250mg
    480,00€
    500mg
    713,00€
  • 5'-(4-Fluorosulfonylbenzoyl)adenosine HCI

    CAS :
    <p>5'-(4-Fluorosulfonylbenzoyl)adenosine HCI is an inhibitor of adenosine deaminase. It has been used as a tool in the diagnosis of autoimmune diseases. 5'-(4-Fluorosulfonylbenzoyl)adenosine HCI binds to the α subunit of mitochondrial ATPase and inhibits its function, leading to a drop in mitochondrial membrane potential. This can be measured by electron paramagnetic resonance spectroscopy, which can detect changes in redox potentials and the presence of disulfide bonds. 5'-(4-Fluorosulfonylbenzoyl)adenosine HCI also binds to DNA synthetase and metal chelate, inhibiting protein synthesis.<br>5'-(4-Fluorosulfonylbenzoyl)adenosine HCI has been shown to inhibit various enzymes such as phosphofructokinase, glycogen phosph</p>
    Formule :C17H17ClFN5O7S
    Degré de pureté :Min. 97.0 Area-%
    Masse moléculaire :489.86 g/mol

    Ref: 3D-W-203807

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  • 5'-Deoxyuridine

    CAS :
    <p>5'-Deoxyuridine is an inorganic, phosphite, and isomeric compound. It can be used as a chromatographic analog to purify uridylic acid. The epimerization reaction of 5'-deoxyuridine with galactose can be catalyzed by dehydrogenase or ion-exchange resin. In addition, 5'-deoxyuridine has the same chemical formula as uridine (C5H5N3O3) but has a different structure: in place of the hydroxyl group on carbon number 5, it has a hydrogen atom. 5'-Deoxyuridine has two isomers: one with the hydroxyl group on carbon number 4 and another with the hydroxyl group on carbon number 2.</p>
    Formule :C9H12N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :228.21 g/mol

    Ref: 3D-ND08410

    10mg
    213,00€
    25mg
    320,00€
    50mg
    501,00€
    100mg
    724,00€
    250mg
    1.288,00€
  • 5-Formylcytidine

    CAS :
    <p>5-Formylcytidine is a nucleoside that belongs to the group of pyrimidine nucleosides. It is structurally similar to cytidine, but with a formyl group in place of the hydroxymethyl group on the C5 position. 5-Formylcytidine has been shown to have an inhibitory effect on mitochondrial protein synthesis and cellular functions in mammalian cells.</p>
    Formule :C10H13N3O6
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :271.23 g/mol

    Ref: 3D-NF63557

    2mg
    352,00€
    5mg
    686,00€
    10mg
    1.022,00€
    25mg
    2.130,00€
    50mg
    3.838,00€
  • 5'-O-Trityluridine

    CAS :
    <p>5'-O-Trityluridine is a nucleoside analogue that has been prepared as an oriented, oxidized, hydrogenated, xylene derivative of uridine. It is composed of ribofuranoside and uridine. The orientation is controlled by the use of trityl groups on the 5' and 3' hydroxyl groups. The alkali metal salt isomers are analysed using HPLC and GC. This compound interacts with phosphotriesters and cyclic phosphodiesters.</p>
    Formule :C28H26N2O6
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :486.52 g/mol

    Ref: 3D-NT06665

    1g
    150,00€
    2g
    229,00€
    5g
    478,00€
    10g
    1.280,00€
    500mg
    134,00€
  • trans-Zeatin Riboside

    CAS :
    <p>Cytokinins are plant hormones involved in developmental processes and in the modulation of plant immune system. Zeatin was identified as the first naturally occurring cytokinin from the endosperm of corn (latin: Zea mays). Water-soluble trans-Zeatin Riboside is a major long-distance signaling molecule in xylem vessels and its action depends on metabolic conversion in proximity to the site of action. Trans-Zeatin Riboside is a powerful agent used in horticulture to improve shoot growth or to induce callus formation (e.g. in tomato). It is used for plant regeneration from leaf explants (e.g. in potato) and for the direct initiation of shoot cultures from bract axils of many plant species.</p>
    Formule :C15H21N5O5
    Masse moléculaire :351.37 g/mol

    Ref: 3D-Z-3000

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  • 2'-Deoxy-2'-fluorocytidine-5'-triphosphate sodium, 100mM aqueous solution


    <p>2'-Deoxy-2'-fluorocytidine-5'-triphosphate sodium, 100mM aqueous solution is a nucleoside analog that is modified at both the 2' position of the sugar (deoxyribose) with a fluoro group and the 5' position with a triphosphate group. This compound is an important tool in biochemistry, molecular biology, and drug development, particularly for studying nucleic acid synthesis and genetic processes.</p>
    Formule :C9H15FN3O13P3•Nax
    Degré de pureté :Min. 95%
    Masse moléculaire :485.15 g/mol

    Ref: 3D-ND157276

    5mg
    463,00€
    10mg
    804,00€
    25mg
    1.722,00€
    2500µg
    323,00€
  • 3'-Deoxy-3'-iodothymidine

    CAS :
    <p>3'-Deoxy-3'-iodothymidine is a nucleoside that is found in DNA. It has a constant of -1.5 and can be protonated to form the anion. The molecule has a reactive radical anion, which is stabilized by electron delocalization with the aromatic rings. 3'-Deoxy-3'-iodothymidine has been studied for use as a medicine for cancer treatment, but it also has applications in biology and chemistry. This compound can be used in conductometry and electron spectroscopy, as well as other chemical experiments that require ionic compounds or radiation.</p>
    Formule :C10H13IN2O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :352.13 g/mol

    Ref: 3D-ND07899

    5mg
    267,00€
    10mg
    401,00€
    25mg
    713,00€
    50mg
    965,00€
    100mg
    1.516,00€
  • 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt

    CAS :
    <p>2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt is a chemically modified nucleotide used in molecular biology and pharmaceutical research. It is a guanosine analog featuring both a 2'-fluoro substitution on the sugar and a 5'-triphosphate group, with tetralithium as the counterion to improve solubility and stability.</p>
    Formule :C10H15FN5O13P3·xLi
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :525.17 g/mol

    Ref: 3D-ND09529

    1mg
    255,00€
    2mg
    410,00€
    5mg
    721,00€
    10mg
    1.222,00€
    25mg
    2.678,00€
  • [1',2',3',4',5'-13C5]-Kinetin riboside


    <p>[1',2',3',4',5'-13C5]-Kinetin riboside is an adenine derivative linked to a ribose sugar moiety. It has also been labeled with ¹³C, a stable isotope of carbon.</p>
    Formule :C5C10H17N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Clear Liquid
    Masse moléculaire :352.29 g/mol

    Ref: 3D-NK161877

    1mg
    679,00€
    2mg
    965,00€
    5mg
    1.705,00€