Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS :<p>2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution is an inhibitor of the methyl transferase domain that is found in all DNA methyltransferases. It has been shown to inhibit transcriptional regulation and cellular transformation, as well as to induce DNA damage. The optimum pH for this compound is 7.4 and it hydrolyzes at pH levels lower than 5.0.</p>Formule :C10H18N3O13P3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :481.18 g/mol2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution
<p>2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution is a synthetic nucleotide analog for use in research</p>Formule :C11H16N5O8P·C12H32N2Degré de pureté :Min. 95%Couleur et forme :Clear liquid.Masse moléculaire :581.64 g/mol4-Amino-5-chloro-2,6-dimethylpyrimidine
CAS :<p>4-Amino-5-chloro-2,6-dimethylpyrimidine is a supramolecular complex that is characterized by the coordination geometry of its metal ion and the donor atoms. It has been proposed as a potential drug for the treatment of bacterial infections, such as tuberculosis. The 4-Amino-5-chloro-2,6,dimethylpyrimidine is structurally similar to nucleobases and may be able to form hydrogen bonds with water molecules. This molecule also has a high melting point and is not soluble in water. It can be protonated at different pH values and forms complexes with hydroxyl groups found in nucleic acids.</p>Formule :C6H8ClN3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :157.6 g/mol2,4-Diamino-6,7-dimethylpteridine
CAS :<p>2,4-Diamino-6,7-dimethylpteridine is a ligand that can bind to an orphan cytosine opposite an abasic site in RNA duplexes</p>Formule :C8H10N6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :190.21 g/mol6-Chloro-9-(b-D-ribofuranosyl)purine
CAS :<p>6-Chloro-9-(b-D-ribofuranosyl)purine is a purine analog that inhibits the synthesis of DNA, RNA, and protein. It has been shown to have physiological effects in cells, and it has been used as a positive control for enzyme activity studies. 6-Chloro-9-(b-D-ribofuranosyl)purine binds to an enzyme called hydroxymethylbilane synthase (HMBS), which inhibits the production of a molecule called tetrahydrobiopterin (THB). THB is essential for the synthesis of nitric oxide (NO), an important neurotransmitter that regulates neuronal death. 6-Chloro-9-(b-D-ribofuranosyl)purine also has significant cytotoxicity against melanoma cells in vitro.</p>Formule :C10H11ClN4O4Degré de pureté :Min. 96 Area-%Couleur et forme :PowderMasse moléculaire :286.68 g/molThymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt
CAS :<p>Thymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt is a precursor in the synthesis of nucleoside sugars in pathways such as rhamnose biosynthesis.</p>Formule :C16H22N2O15P2Na2Degré de pureté :Min. 85 Area-%Couleur et forme :White PowderMasse moléculaire :590.28 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine
<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is a modified nucleoside with antiviral activity. This compound is synthesized by a modified method that avoids the use of phosphoramidites, which are usually used to synthesize nucleosides. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)adenosine is an activator of viral RNA polymerase and has been shown to be active against HIV and herpes simplex virus type 1.</p>Degré de pureté :Min. 95%N6-Cyclopentyl-2'-C-methyl-adenosine
CAS :<p>N6-Cyclopentyl-2'-C-methyl-adenosine is an antiviral agent that inhibits the synthesis of DNA by preventing the formation of RNA from DNA. It has been shown to be effective against HIV and other retroviruses. N6-Cyclopentyl-2'-C-methyl-adenosine is a synthetic nucleoside that is activated by phosphorylation in cells, which leads to the synthesis of monophosphate (5'-AMP). This compound is used for the treatment of cancer and HIV infection.</p>Formule :C16H23N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.39 g/mol2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine
CAS :<p>2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine is a protected nucleoside derivative that can potentially be used as an intermediate in the chemical synthesis of nucleoside analogs, especially for RNA or DNA oligonucleotides. This compounds has a 2,6-Diaminopurine – a purine analog structurally similar to adenine but with an additional amino group at the 2-position and a β-D-ribofuranosyl. The 3′ and 5′ hydroxyl groups of the ribose are protected with a bulky 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS) group. This is a silyl protecting group often used to block reactivity during nucleoside synthesis.</p>Formule :C22H40N6O5Si2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :524.77 g/mol2'-Deoxy-2'-fluoroguanosine
CAS :<p>2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.</p>Formule :C10H12FN5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :285.23 g/molDeoxyribonucleic acid low molecular weight from salmon sperm
CAS :<p>This low molecular DNA (deoxyribonucleic acid) from salmon sperm is a fragment that is an effective indicator of the presence of guanine in urine samples, and can be used to detect lipoperoxidation in animal hemocytes. It has also been shown to be a sublethal oxidative stress agent for human urine, which induces irreversible oxidation in the enzyme activities of signal detection. According to some recent research studies, this product is being investigated as an environmental pollutant indicator and could be used as an effective wastewater treatment method.</p>Couleur et forme :Powder3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS :<p>Used as a protected adenosine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group is a bulky, acid-labile protecting group specifically designed to protect the 3' and 5' hydroxyl groups of ribonucleosides during RNA oligonucleotide synthesis.</p>Formule :C22H39N5O5Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :509.76 g/mol2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution
CAS :<p>2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution, is a synthetic nucleotide analog. It has potential application in antiviral research, particularly for studying RNA-dependent RNA polymerase (RdRP) activity in RNA viruses. It mimics the natural cytidine triphosphate (CTP) but includes a 2'-C-methyl modification on the ribose sugar.</p>Formule :C10H18N3O14P3·4C6H15NDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :901.94 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS :<p>2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.</p>Formule :C35H37N5O6Degré de pureté :Min. 95%Couleur et forme :Off-White To Light (Or Pale) Yellow SolidMasse moléculaire :623.72 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS :<p>5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.</p>Formule :C34H38N2O9Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :618.67 g/mol9-(2',3',5'-Tri-O-benzyl-β-D-arabinofuranosyl)adenine
CAS :<p>9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is a nucleoside that has shown anticancer and antiviral properties. It inhibits replication of DNA and RNA in cells, which may be due to its ability to inhibit the synthesis of deoxyribonucleotides and ribonucleotides. This compound is synthetically produced from 2',3',5'-tri-O-benzyl b-D-arabinofuranosyl chloride and adenine monophosphate (AMP). 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is also known as arabinoside A.</p>Formule :C31H31N5O4Degré de pureté :Min. 95%Masse moléculaire :537.61 g/mol5'-Deoxythymidine
CAS :<p>5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.</p>Formule :C10H14N2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :226.23 g/molβ-Nicotinamide adenine dinucleotide
CAS :<p>Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.</p>Formule :C21H27N7O14P2Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :663.43 g/molUridine 5'-triphosphate dihydrate trisodium salt
CAS :<p>Uridine 5'-triphosphate dihydrate trisodium salt is a nucleotide that is involved in the synthesis of RNA. This product has been used as a supplement to promote healthy eyes and skin, as well as to treat Alzheimer's disease. It has been shown to be an efficient method for the detection of active substances by hydrophilic interaction chromatography (HILIC). The HILIC method involves separating molecules based on their hydrophobic or hydrophilic properties, which are determined by the ionic strength of the solution. Uridine 5'-triphosphate dihydrate trisodium salt binds with chloride ions, which prevents it from binding with other organic compounds. The chloride ions then serve as an end point that can be detected using ultraviolet light.</p>Formule :C9H12N2O15P3·3Na·2H2ODegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :586.12 g/molN6,3'-O-Dibenzoyl-2'-deoxyadenosine
CAS :<p>N6,3'-O-Dibenzoyl-2'-deoxyadenosine is a nucleoside that is used as a biochemical reagent in molecular biology. N6,3'-O-Dibenzoyl-2'-deoxyadenosine has been shown to be an inhibitor of the enzyme phosphodiesterase and also binds to DNA. This compound has been shown to have antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Clostridium perfringens. The lipophilicity of this compound allows it to cross the cell membrane and cleave DNA at the site of replication. N6,3'-O-Dibenzoyl-2'-deoxyadenosine is an analog of 6,4’-dihydroxybenzophenone (DBP) and can be synthesized from DBP by reacting with dibenzoyl chloride in chloroform</p>Formule :C24H21N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :459.47 g/molN4-Benzoyl-2'-deoxycytidine
CAS :<p>N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.</p>Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :331.33 g/mol2-Aminoperimidine hydrochloride
CAS :<p>2-Aminoperimidine hydrochloride is the hydrochloride salt of 2-aminoperimidine, a polycyclic aromatic heterocycle featuring a fused naphthalene–pyrimidine ring system with an amino group at the 2-position. The protonated amino group forms a stable crystalline salt with hydrochloric acid, enhancing aqueous solubility and facilitating handling in laboratory applications.</p>Formule :C11H9N3•(HCl)xDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :219.67 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS :<p>1-(2'-Deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.</p>Formule :C24H24N4O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :464.48 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
CAS :<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a new nucleoside analogue that is a phosphoramidite. It has been synthesized as an anticancer agent and antiviral drug. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine has been shown to inhibit the growth of human tumor cells in vitro, suggesting that it may have anticancer activity. This compound also inhibits viral replication by inhibiting DNA synthesis and RNA transcription in infected cells.</p>Formule :C41H43N3O9Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :721.79 g/molN4-Benzoyl-2'-deoxy-2'-fluorocytidine
CAS :<p>N4-Benzoyl-2'-deoxy-2'-fluorocytidine is a novel, synthetic nucleoside that has been shown to inhibit the growth of cancer cells and is being investigated as a potential anticancer drug. N4-Benzoyl-2'-deoxy-2'-fluorocytidine has also been found to be active against HIV, Herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), and influenza A virus. It prevents the replication of viruses by inhibiting DNA synthesis in the host cell.</p>Formule :C16H16FN3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.31 g/molCyclic adenosine 5'-diphosphate ribose ammonium salt
CAS :<p>Cyclic Adenosine 5'-diphosphate ribose ammonium salt (CADPRAM) is a potent inhibitor of cyclic nucleotide phosphodiesterases (PDEs). CADPRAM reversibly inhibits PDEs and prevents the hydrolysis of cAMP. This inhibition can lead to an increase in cytosolic Ca2+. CADPRAM also inhibits polymerase chain reaction, which is why it cannot be used for the treatment of infectious diseases. CADPRAM has been shown to inhibit the activity of enzymes that are known to play a role in clinical pathology, such as adenylate cyclase and phosphodiesterase type 3.</p>Formule :C15H21N5O13P2·NH3Degré de pureté :Min. 95%Couleur et forme :White solid.Masse moléculaire :558.33 g/molBiotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
CAS :<p>Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel, synthetic and highly purified ribonucleoside phosphoramidite. It is used as an activator of nucleic acid synthesis in the preparation of DNA and RNA. Biotin-5-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has been shown to be effective against various types of cancer cells, including leukemic cells and breast cancer cells. The drug also inhibits the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 2 (HSV-2).</p>Formule :C22H35N6O16P3S·xLiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :764.53 g/molThymidine-5'-triphosphate trisodium
CAS :<p>Thymidine-5'-triphosphate or dTTP, is a nucleotide used by the cell to synthesize DNA molecules. Thymidine-5'-triphosphate is used in molecular biology techniques and assays as a substrate of the enzyme DNA polymerase, e.g. polymerase chain reaction (PCR), DNA sequencing, pyrosequencing reactions. Salt form of thymidine-5'-triphosphate has been used in a newly developed detection system for SARS-CoV-2 that combines bioluminescence in real-time (BART) with reverse-transcriptase loop-mediated amplification (RT-LAMP).</p>Formule :C10H17N2O14P3•Na3Degré de pureté :(%) Min. 90%Couleur et forme :White PowderMasse moléculaire :551.14 g/mol3'-O-Allylguanosine
<p>3'-O-Allylguanosine is a antiviral agent that belongs to the group of synthetic nucleosides. It is a monophosphate analog of guanosine and an activator of ribonucleotide reductase. 3'-O-Allylguanosine has been shown to be effective against cancer cells in vitro. It has also been shown to inhibit DNA synthesis and promote DNA degradation in human leukemia cells, suggesting its potential use for the treatment of leukemia.</p>Formule :C13H17N5O5Degré de pureté :Min. 95%Masse moléculaire :323.3 g/mol5-Bromo-2'-deoxyuridine
CAS :<p>5-Bromo-2'-deoxyuridine (5-BrDU) is a nitrate reductase inhibitor that prevents the reduction of nitrate to nitrite by inhibiting the enzyme nitrate reductase. It is a genotoxic agent that has been shown to cause DNA damage and cell death in vitro. 5-BrDU has been shown to induce preconditioning in vivo, reducing neuronal injury after ischemia. This drug also binds to NMDA receptors and may be useful as a model system for studying neurodegenerative diseases such as Alzheimer's disease. 5-BrDU has been shown to inhibit the polymerase chain reaction in wild-type strains of bacteria, but not in strains with a mutation in their DNA gyrase genes.</p>Formule :C9H11BrN2O5Degré de pureté :Min. 99 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :307.1 g/mol2'-Deoxyadenosine-5'-triphosphate disodium salt
CAS :<p>2'-Deoxyadenosine-5'-triphosphate disodium salt is a nucleotide that is formed from adenosine triphosphate (ATP) and deoxyadenosine monophosphate (dAMP). It is an intermediate in the biosynthesis of fatty acids, which are important components of cell membranes. This nucleotide can be used to measure the light exposure of bacteria. 2'-Deoxyadenosine-5'-triphosphate disodium salt has been shown to have antibacterial activity against some Gram-positive bacteria, such as Staphylococcus aureus. The effective dose for these bacteria is 5 µg/mL with a linear model. The biological properties of this nucleotide are still not fully understood, but it is thought to play a role in blood pressure regulation through its effects on fatty acid synthesis.</p>Formule :C10H14N5O12P3Na2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :535.15 g/molCoenzyme A sodium salt hydrate
CAS :<p>Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.</p>Formule :C21H36N7O16P3SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :790.53 g/mol5-Aminouridine
CAS :<p>5-Aminouridine is an analog of uridine that is used in the synthesis of RNA. It inhibits the synthesis of RNA by viruses, and it may also inhibit the synthesis of RNA by cells, including muscle cells. 5-Aminouridine has been shown to inhibit protein synthesis in muscle cells incubated with orotic acid. The drug may also interact with other drugs metabolized by UDP-glucose pyrophosphorylase, such as carbamazepine and phenytoin. This interaction may lead to decreased serum levels of these drugs following treatment with 5-aminouridine.</p>Formule :C9H13N3O6Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :259.22 g/molN4-Benzoyl-5-methylcytidine
CAS :<p>N4-Benzoyl-5-methylcytidine is a labile chemical that can be uniquely prepared using biochimie. It has been shown to have anticodon activity in assays and is synthesized chemically. The nucleoside is phosphoramidite, which is methylated and reproducible. N4-Benzoyl-5-methylcytidine has been shown to inhibit the growth of cells by blocking the synthesis of purines and pyrimidines. It may also have biophysical properties that are related to its ability to bind to DNA.</p>Formule :C17H19N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :361.35 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine is a pesticide that is used as an acaricide, insecticide, and nematicide. It has been shown to be effective in controlling the growth of E. coli and insects by binding to their membranes and inhibiting lipid synthesis. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine binds to the polypeptides in the bacterial cell membrane and inhibits their function, leading to cell death. This drug also has a low toxicity for mammals.</p>Formule :C37H35N3O7Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :633.69 g/mol2'-Deoxy-2',2'-difluoro-5-methyluridine
CAS :<p>2'-Deoxy-2',2'-difluoro-5-methyluridine is a synthetic nucleoside analog for use in research</p>Formule :C10H12F2N2O5Degré de pureté :Min. 95%Masse moléculaire :278.21 g/mol2'-O-Methyladenosine 5'-triphosphate lithium - 100 mM aqueous solution
CAS :<p>2'-O-Methyladenosine 5'-triphosphate lithium is a novel nucleotide that has been synthesized to act as an antiviral and anticancer agent. It can be used in the production of ribonucleosides, deoxyribonucleosides, and modified DNA. It is also a high quality phosphoramidite that can be used in the synthesis of DNA and RNA. 2'-O-Methyladenosine 5'-triphosphate lithium has been shown to inhibit the replication of HIV-1 and other viruses by inhibiting viral transcription. It is also active against cancer cells, with an IC50 value of 0.2 μM for HL-60 cells.</p>Formule :C11H18N5O13P3•Li3Degré de pureté :Min. 95%Masse moléculaire :542 g/mol7-Deazaguanosine
CAS :<p>7-Deazaguanosine is a low energy analog of guanosine that has been shown to be activated by trifluoroacetic acid, which is a chemical reagent that can be used for the activation of nucleosides. 7-Deazaguanosine is used in the treatment of human serum and urine viruses such as hepatitis B virus, herpes simplex virus, and cytomegalovirus. The compound has also been shown to have receptor agonism activity on toll-like receptors. 7-Deazaguanosine has been shown to have antiviral effects against HIV and influenza A (H1N1). 7-Deazaguanosine binds at the viral receptor site and blocks the entry process into cells. This drug also stimulates macrophages to produce cytokines, which are proteins that regulate immune responses.</p>Formule :C11H14N4O5Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :282.26 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a connector that is used in optical devices. It is a ligand that binds to the constant region of the antibody, which is part of the molecule that protects against bacteria and viruses. The residue has been shown to have variable conformation in tetrahydrofuran and ethyl group. This molecule can be injected into dimethylformamide with an anion chloride or pyrrolidine ring.</p>Formule :C38H37N3O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :647.72 g/mol2′-O-2-Methoxy-2-oxoethyl-5-methyl-cytidine
<p>2′-O-2-Methoxy-2-oxoethyl-5-methylcytidine (2′OMeC) is a synthetic ribonucleoside that is used in DNA synthesis. 2′OMeC is a nucleotide analog that inhibits DNA and RNA synthesis by competitively inhibiting the enzyme activity of DNA polymerase, RNA polymerase, and other enzymes involved in the process. This drug has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). It also has anticancer properties through its ability to inhibit protein synthesis. The novel structure of this drug gives it high quality and purity.</p>Formule :C13H19N3O7Degré de pureté :Min. 95%Masse moléculaire :329.31 g/mol6-Azauridine
CAS :<p>Inhibitor of uridine monophosphate synthase</p>Formule :C8H11N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :245.19 g/mol2,4-Diamino-6-hydroxy-5-nitrosopyrimidine
CAS :<p>2,4-Diamino-6-hydroxy-5-nitrosopyrimidine is a nucleoside for use in research applications</p>Formule :C4H5N5O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :155.12 g/mol2′-O-[2-(Methylamino)-2-oxoethyl]guanosine
CAS :<p>2′-O-[2-(Methylamino)-2-oxoethyl]guanosine is a monophosphate nucleoside with anticancer properties. It has been shown to activate the transcription of genes that regulate cell growth and differentiation, and to induce apoptosis in tumor cells. This compound is an analog of guanosine, which is not modified at the 2′ position. It has been used to synthesize phosphoramidites for oligonucleotide synthesis, and may be useful as a novel therapeutic agent for cancer treatment.</p>Formule :C13H18N6O6Degré de pureté :Min. 95%Masse moléculaire :354.32 g/molUridine 5'-diphosphate disodium salt
CAS :<p>Agonist of P2Y6 purinoceptor; antagonist of P2Y14</p>Formule :C9H12N2O12P2Na2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :448.12 g/mol1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil
CAS :<p>1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.</p>Formule :C11H11FN2O5Degré de pureté :Min. 95%Masse moléculaire :270.21 g/mol2'-O-Methyladenosine 5'-triphosphate lithium salt - 100 mM aqueous solution
CAS :<p>2'-O-Methyladenosine 5'-triphosphate lithium salt - 100 mM aqueous solution is a modified nucleoside that has antiviral, anticancer, and antimalarial properties. It also has been shown to activate DNA synthesis and inhibit the growth of cancer cells.</p>Formule :C11H18N5O13P3·xLiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :521.21 g/mol2',3'-Dideoxyadenosine-5'-monothiophosphate
CAS :<p>2',3'-Dideoxyadenosine-5'-monothiophosphate is a nucleoside for use in research applications</p>Formule :C10H14N5O4PSDegré de pureté :Min. 95%Couleur et forme :Clear liquid.Masse moléculaire :331.29 g/mol2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt - Aqueous solution
CAS :<p>2'-C-Methyladenosine 5'-triphosphate triethyl ammonium salt is a synthetic nucleotide analog of adenosine triphosphate (ATP), modified at the 2'-carbon of the ribose ring. This molecule has potential applications in biochemical, enzymatic, and antiviral research, particularly in studies involving RNA synthesis and viral RNA polymerases.</p>Formule :C35H79N9O13P3Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :926.98 g/molFludarabine
CAS :<p>Fludarabine is a purine analog and works by interfering with DNA synthesis, which helps to stop the growth of cancer cells.</p>Formule :C10H12FN5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :285.23 g/mol2'-Deoxy-5-hydroxymethyluridine-5'-triphosphate triethylammonium
CAS :<p>2'-Deoxy-5-hydroxymethyluridine-5'-triphosphate triethylammonium salt (dHMUTP) is a noncompetitive inhibitor of transcriptase activity. It inhibits the synthesis of DNA by binding to RNA polymerase on the template strand, thereby blocking the progress of the enzyme along the DNA. This drug has been shown to be effective in inhibiting viral production and growth in mammalian cells, as well as cancer cell culture. Dihydrofolate reductase is required for dHMUTP to function, and it is metabolized in vivo through hydrolysis by glycosylases or antineoplastic properties by nucleotide excision repair enzymes. These enzymes are present in human cells but absent in bacteria and yeast. The drug also has antineoplastic properties due to its ability to inhibit tumor cell proliferation.</p>Formule :C10H16N2O15P3·C6H16NDegré de pureté :Min. 70 Area-%Couleur et forme :PowderMasse moléculaire :599.36 g/mol
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