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Nucléotides

Nucléotides

Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.

Sous-catégories appartenant à la catégorie "Nucléotides"

2634 produits trouvés pour "Nucléotides"

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  • Pyrimidine-4-carboxylic acid methyl ester

    CAS :
    <p>The pyrimidine-4-carboxylic acid methyl ester is a neutralized derivative of the natural amino acid pyrimidine-4-carboxylic acid. It can be metabolized in vivo to the active form, bleomycin. The neutralized form is useful for the synthesis of betaines and other compounds. This product is also used as an intermediate in the synthesis of metastable carbenes that are difficult to synthesize by other means. Pyrimidine-4-carboxylic acid methyl ester has been used as a reagent in mass spectrometry to identify isotopomers and isomers. It can also be used as a precursor for chemical transfer reactions with carbenes.</p>
    Formule :C6H6N2O2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :138.12 g/mol

    Ref: 3D-NP57387

    5g
    135,00€
    10g
    178,00€
    25g
    724,00€
  • Diquafosol Impurity 2

    CAS :
    <p>Diquafosol Impurity 2 is a high-purity phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleosides. This product is also a novel activator for phosphoramidites. Diquafosol Impurity 2 has CAS No. 63785-59-1 and a molecular weight of 228.24 g/mol. It is insoluble in water, but soluble in most organic solvents.</p>
    Formule :C18H25N4O20P3
    Degré de pureté :Min. 95%
    Masse moléculaire :710.33 g/mol

    Ref: 3D-ND182891

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  • 5-Methylcytidine-5'-monophosphate

    CAS :
    <p>5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.</p>
    Formule :C10H16N3O8P
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :337.22 g/mol

    Ref: 3D-NM29555

    1mg
    254,00€
    2mg
    382,00€
    5mg
    543,00€
    10mg
    804,00€
    25mg
    1.516,00€
  • Uridine 5'-monophosphate

    CAS :
    <p>Uridine 5'-monophosphate (UMP) is a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. UMP has been shown to inhibit the protein synthesis of cells by inhibiting the enzyme activities of DNA polymerase and RNA polymerase. <br>It also inhibits the synthesis of p2y receptors, which are involved in cell proliferation and differentiation. Further studies suggest that UMP may be an effective anti-inflammatory agent due to its ability to decrease prostaglandin production.</p>
    Formule :C9H13N2O9P
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :324.18 g/mol

    Ref: 3D-NU05691

    2g
    268,00€
    5g
    467,00€
    10g
    708,00€
    25g
    1.084,00€
    50g
    1.334,00€
  • 4-Demethylwyosine

    CAS :
    <p>4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.</p>
    Formule :C13H15N5O5
    Degré de pureté :Min. 80 Area-%
    Couleur et forme :Powder
    Masse moléculaire :321.29 g/mol

    Ref: 3D-ND159486

    1mg
    349,00€
    2mg
    478,00€
    5mg
    906,00€
    10mg
    1.019,00€
    500µg
    243,00€
  • 2',3'-O-Isopropylideneguanosine

    CAS :
    <p>2',3'-O-Isopropylideneguanosine is a nucleoside for use in research applications</p>
    Formule :C13H17N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :323.31 g/mol

    Ref: 3D-NI06120

    1kg
    1.936,00€
    50g
    344,00€
    100g
    502,00€
    250g
    908,00€
    500g
    1.259,00€
  • 8-Hydroxyadenosine

    CAS :
    <p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>
    Formule :C10H13N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :283.25 g/mol

    Ref: 3D-NH08494

    1g
    883,00€
    2g
    1.494,00€
    100mg
    255,00€
    250mg
    477,00€
    500mg
    639,00€
  • 2'-O-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution

    CAS :
    <p>2'-O-Methylcytidine-5'-triphosphate sodium salt is a synthetic, modified nucleoside analog. It can be used as an antiviral agent and anticancer drug to inhibit viral replication and tumor growth. 2'-O-Methylcytidine-5'-triphosphate sodium salt has the ability to activate cellular DNA synthesis. This compound also inhibits RNA polymerase activity in cancer cells, which inhibits the production of proteins vital for cell division. 2'-O-Methylcytidine-5'-triphosphate sodium salt can be used as a phosphoramidite building block for the synthesis of oligonucleotides with novel structures.</p>
    Formule :C10H18N3O14P3·xNa
    Degré de pureté :Min. 95%
    Couleur et forme :Clear Liquid
    Masse moléculaire :497.18 g/mol

    Ref: 3D-NM157273

    5mg
    500,00€
    10mg
    758,00€
    25mg
    1.516,00€
    50mg
    2.684,00€
    2500µg
    296,00€
  • Poly(2'-O-Methyladenosine 5'-monophosphate) sodium

    CAS :
    <p>Please enquire for more information about Poly(2'-O-Methyladenosine 5'-monophosphate) sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :(C11H16N5O7P)x•Nax
    Degré de pureté :Min. 95%

    Ref: 3D-NP184153

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  • Triciribine

    CAS :
    <p>Protein kinase B inhibitor;</p>
    Formule :C13H16N6O4
    Degré de pureté :Min. 95%
    Couleur et forme :White/Off-White Solid
    Masse moléculaire :320.3 g/mol

    Ref: 3D-NT08796

    5mg
    135,00€
    10mg
    149,00€
  • 2',3'-Anhydroadenosine

    CAS :
    <p>2',3'-Anhydroadenosine is a nucleoside for a range of applications</p>
    Formule :C10H12N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :240.21 g/mol

    Ref: 3D-NA145605

    25mg
    234,00€
    50mg
    402,00€
    100mg
    663,00€
    250mg
    1.366,00€
  • 1'-13CUridine

    CAS :
    <p>1'-13CUridine is a nucleoside analog attached to an isotope</p>
    Formule :CC8H12N2O6
    Couleur et forme :Powder
    Masse moléculaire :245.19 g/mol

    Ref: 3D-NU34299

    10mg
    305,00€
    25mg
    531,00€
    50mg
    845,00€
    100mg
    1.354,00€
    250mg
    2.871,00€
  • N1-Methyladenosine-5’-monophosphate

    CAS :
    <p>The N1-methyladenosine is a reversible modification in tRNA, mRNA and long non-coding RNA</p>
    Formule :C11H16N5O7P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :361.25 g/mol

    Ref: 3D-NM184154

    5mg
    135,00€
    100mg
    607,00€
    500mg
    1.355,00€
  • Kinetin riboside

    CAS :
    <p>Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.</p>
    Formule :C15H17N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :347.33 g/mol

    Ref: 3D-NK06717

    1g
    325,00€
    2g
    509,00€
    5g
    965,00€
    10g
    1.743,00€
    25g
    3.506,00€
  • Capecitabine

    CAS :
    <p>Pro-drug of 5-FU; anti-cancer agent</p>
    Formule :C15H22FN3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :359.35 g/mol

    Ref: 3D-ND09160

    2g
    203,00€
    5g
    390,00€
    10g
    610,00€
    25g
    1.206,00€
    50g
    2.013,00€
  • N-Cbz gemcitabine

    CAS :
    <p>N-Cbz gemcitabine is a novel nucleoside analog that is chemically modified to be activated by enzymes in the cell. It has been shown to have high purity and high quality. In addition, N-Cbz gemcitabine is an anticancer drug that is most effective against cells with a low number of nucleotides per cell. This drug has shown antiviral properties and is used for the treatment of HIV/AIDS patients.</p>
    Formule :C17H17F2N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White To Yellow Solid
    Masse moléculaire :397.33 g/mol

    Ref: 3D-NC16645

    5mg
    208,00€
    10mg
    323,00€
    25mg
    491,00€
  • 2-Thiocytidine

    CAS :
    <p>2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.</p>
    Formule :C9H13N3O4S
    Degré de pureté :Min. 95%
    Couleur et forme :Yellow Powder
    Masse moléculaire :259.28 g/mol

    Ref: 3D-NT02911

    25mg
    324,00€
    50mg
    487,00€
    100mg
    678,00€
    250mg
    1.208,00€
    500mg
    1.936,00€
  • N6-Etheno 2'-deoxyadenosine

    CAS :
    <p>N6-Etheno 2'-deoxyadenosine is a nucleoside analogue that inhibits DNA synthesis by binding to the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate to thymidine monophosphate. This drug has been shown to be genotoxic in vitro and in vivo, as evidenced by its ability to induce chromosomal aberrations in cultured human lymphocytes and disrupt DNA replication in mammalian cells. It also reacts with mismatched base pairs and dna duplexes, leading to their degradation. N6-Etheno 2'-deoxyadenosine binds reversibly to antibodies and can be detected using an analytical method that employs monoclonal antibodies.</p>
    Formule :C12H13N5O3
    Couleur et forme :White Off-White Powder
    Masse moléculaire :275.26 g/mol

    Ref: 3D-NE06241

    10mg
    223,00€
    25mg
    350,00€
    50mg
    517,00€
    100mg
    614,00€
    250mg
    917,00€
  • 3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine

    CAS :
    <p>3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine is an inorganic, deoxyribonucleoside. It is the acetyl derivative of 2'-deoxy-5-iodouridine, which is an analog of uracil. 3',5'-Di-O-acetyl-2'-deoxy-5-iodouridine has been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2) in animals. This drug also has antiangiogenic properties, inhibiting the growth of new blood vessels and tissues at the site of a tumour. Studies have shown that 3',5'-di-O acetyl 2'-deoxyuridine can be incorporated into exudates from human cancer patients and can inhibit tumor cell proliferation in vivo.</p>
    Formule :C13H15IN2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :438.18 g/mol

    Ref: 3D-ND08349

    1g
    349,00€
    250mg
    159,00€
    500mg
    215,00€
  • 2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine

    CAS :
    <p>2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine is a nucleoside that can be used as an anticancer drug and antiviral agent. It has shown potent in vitro cytotoxic activity against human leukemia cells and other cancer cell lines, including breast, prostate, ovarian, and colon cancers. 2′-O-(2-Methoxy-2-oxoethyl)-5-methyl-uridine also has good antiherpetic potential. This compound is a novel and synthetic nucleoside with high purity, high quality, and excellent stability. It is soluble in water, methanol, ethanol, acetone, acetonitrile; slightly soluble in chloroform; insoluble in ether or hexane. CAS No. 149301-23-5</p>
    Formule :C13H18N2O8
    Degré de pureté :Min. 95%
    Masse moléculaire :330.29 g/mol

    Ref: 3D-NM182885

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    À demander
  • 5-Chloro-2',3'-dideoxy-3'-fluorouridine

    CAS :
    <p>5-Chloro-2',3'-dideoxy-3'-fluorouridine is a nucleoside analog that inhibits the replication of HIV by competing with other nucleosides for incorporation into viral DNA, thereby inhibiting the production of new viruses. This drug has been shown to have an inhibitory effect on the replication of HIV and has been approved as an antiretroviral agent. 5-Chloro-2',3'-dideoxy-3'-fluorouridine is active against most HIV strains and is able to suppress viral load in patients with chronic hepatitis B or C. It also inhibits the hepatic metabolism of drugs metabolized by cytochrome P450 enzymes, such as CYP3A4 inducers. The effective dose for this drug ranges from 100 mg to 200 mg per day.</p>
    Formule :C9H10ClFN2O4
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :264.64 g/mol

    Ref: 3D-NC58336

    5mg
    274,00€
    10mg
    420,00€
    25mg
    765,00€
    50mg
    1.137,00€
    100mg
    1.820,00€
  • 2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

    CAS :
    <p>2-Amino-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a protected nucleoside analog.In this compound the sugar’s hydroxyl groups are acetylated to make it chemically stable and reactive in nucleoside chemistry.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA145604

    2g
    135,00€
    5g
    143,00€
    10g
    203,00€
    20g
    345,00€
  • 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine

    CAS :
    <p>2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is a nucleoside that can be used as an anticancer, antiviral, and anticoagulant. It is synthesized from the natural nucleosides adenosine and cytidine. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine has been shown to inhibit the growth of tumor cells in vitro. This compound also inhibits viral replication by inhibiting DNA synthesis through inhibition of ribonucleotide reductase and deoxyribonucleotide reductase. 2′-O-[2-(Methylamino)-2-oxoethyl]adenosine is phosphorylated by ATP to produce 2′-O-[2-(methylamino)-2-oxoethyl]adenosinophosphate (AMP). AMP then binds to the purinergic receptor P1, which leads to</p>
    Formule :C13H18N6O5
    Degré de pureté :Min. 95%
    Masse moléculaire :338.32 g/mol

    Ref: 3D-NM182883

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    À demander
  • 1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-iodouracil


    <p>1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-iodouracil is a modified nucleoside analog for research applications. It contains a uracil base with an iodine atom, a fluorinated sugar that produces increased metabolic stability and benzoyl-protecting groups at the 3'- and 5'-hydroxyl positions, commonly used in nucleoside synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND158761

    1g
    167,00€
    500mg
    134,00€
  • N6-Benzoyl-2'-O-methyladenosine

    CAS :
    <p>N6-Benzoyl-2'-O-methyladenosine is a nucleoside that is chemically synthesized. It has been shown to be an inhibitor of the polyhedrosis virus, which causes an infectious disease in silkworms. N6-Benzoyl-2'-O-methyladenosine also inhibits viral replication by interfering with the synthesis of messenger RNA. This compound can be used as a silver nitrate or silver salt prodrug for treating diseases caused by viruses and bacteria. This drug is not active against DNA viruses because it does not possess phosphate groups on its structure.</p>
    Formule :C18H19N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :385.37 g/mol

    Ref: 3D-NB57530

    5g
    363,00€
    10g
    509,00€
    25g
    965,00€
    50g
    1.667,00€
    100g
    2.952,00€
  • 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt

    CAS :
    <p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate tetralithium salt (FdATP) is a competitive inhibitor of ATP. It inhibits the synthesis of RNA, DNA, and protein in cell culture at high concentrations. FdATP is also an analog of adenosine triphosphate (ATP), which is needed for cellular energy production. The competitive inhibition of ATP by FdATP prevents the formation of a phosphorylated enzyme that is required for the initiation of DNA synthesis. This can lead to cell death, as the cells cannot produce proteins required for growth and replication.</p>
    Formule :C10H11FN5O12P3•Li4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :532.9 g/mol

    Ref: 3D-ND15214

    1mg
    229,00€
    2mg
    344,00€
    5mg
    611,00€
    10mg
    927,00€
    25mg
    1.706,00€
  • 2'-Deoxyadenosine monohydrate

    CAS :
    <p>2'-Deoxyadenosine monohydrate (2'-dA) is an adenosine nucleotide that is synthesized by the enzyme adenosine kinase. It is a competitive inhibitor of phosphodiesterase and inhibits the activity of this enzyme, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis. 2'-dA has been shown to have sublethal effects on neurons at concentrations that are below those required for neuronal death and apoptosis. This may be due to its ability to inhibit the synthesis of ATP, thereby limiting the production of phosphoryl groups from ATP. The inhibition of ATP synthesis also reduces the amount of energy available for other processes within cells.</p>
    Formule :C10H13N5O3•H2O
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :269.26 g/mol

    Ref: 3D-ND04011

    1kg
    5.590,00€
    50g
    425,00€
    100g
    700,00€
    250g
    1.518,00€
    500g
    2.894,00€
  • 5'-O-tert-Butyldiphenylsilyl-thymidine

    CAS :
    <p>5'-O-tert-Butyldiphenylsilyl-thymidine (TBS-T) is a class of nucleoside that is synthesized by condensation of two molecules of 5'-O-tert-butyldiphenylsilyl-2',3'-dideoxyuridine (TBDPS) and N6-benzoyladenine. TBS-Ts are used in the synthesis of phosphorothioate oligodeoxynucleotides. They have been shown to be useful as activators for the formation of phosphite linkages at the 3' terminus of DNA oligonucleotides. TBS-T is also used in other applications, such as the preparation of diastereomerically pure nucleosides for use in chemical reactions.</p>
    Formule :C26H32O5N2Si
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :480.63 g/mol

    Ref: 3D-NB158765

    1g
    151,00€
    2g
    227,00€
    5g
    472,00€
    10g
    735,00€
    25g
    1.407,00€
  • Thymidine 3′-monophosphate disodium

    CAS :
    <p>Thymidine 3′-monophosphate disodium is a chemotherapeutic agent that has been shown to have antiviral and anticancer properties. It is a nucleoside analogue, which mimics the structure of thymidine and inhibits DNA synthesis by interfering with the DNA replication process. Thymidine 3′-monophosphate disodium is also used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides. This product is synthetic, high quality, and not chemically modified. It has CAS number 68698-19-1 and molecular weight of 242.06 g/mol.</p>
    Formule :C10H15N2O8P•Na2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :368.19 g/mol

    Ref: 3D-NT182950

    2mg
    192,00€
    5mg
    375,00€
    10mg
    534,00€
    25mg
    949,00€
    50mg
    1.431,00€
  • 5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt

    CAS :
    <p>5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt is a novel antiviral agent that inhibits viral replication by competing with natural nucleosides for incorporation into the viral DNA or RNA. The 5'-O-DMT group prevents the elimination of thymidine from the monophosphate form. This product has a high purity and quality, as well as potent antiviral activity against HIV and other viruses.</p>
    Formule :C35H36N2O10·xC6H15N
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :745.86 g/mol

    Ref: 3D-ND08490

    2g
    235,00€
    5g
    479,00€
    10g
    759,00€
    25g
    1.735,00€
    50g
    3.168,00€
  • 2-Methylthioadenosine

    CAS :
    <p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>
    Formule :C11H15N5O4S
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :313.34 g/mol

    Ref: 3D-NM09610

    2mg
    305,00€
    5mg
    467,00€
    10mg
    724,00€
    25mg
    1.137,00€
    50mg
    1.895,00€
  • 5'-O-(4,4'-Dimethoxytrityl)adenosine

    CAS :
    <p>5'-O-(4,4'-Dimethoxytrityl)adenosine is a phosphoramidite that can be used as an activator for the synthesis of DNA. It is also used in the preparation of modified nucleosides and has anticancer activity. 5'-O-(4,4'-Dimethoxytrityl)adenosine is a modified ribonucleoside with high quality and high purity. This product has been shown to have antiviral activity against HIV-1.</p>
    Formule :C31H31N5O6
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :569.61 g/mol

    Ref: 3D-ND15508

    2g
    231,00€
    5g
    434,00€
    10g
    617,00€
    25g
    1.103,00€
  • 5'-Deoxy-5-fluorocytidine

    CAS :
    <p>5'-Deoxy-5-fluorocytidine is a cytosolic nucleoside analogue that is phosphorylated by cellular enzymes to the active form 5'-deoxy-5-fluorouridine monophosphate. It is a prodrug, which is activated in the body to release 5-FU and inhibits the growth of cancer cells. 5'-Deoxy-5-fluorocytidine has been shown to be effective against metastatic colorectal cancer in humans and resistant breast cancer in mice. The drug can also be used as an oral prodrug for 5-FU, which has a wide therapeutic index and low toxicity. Studies have shown that it selectively inhibits proliferation of solid tumours through inhibition of protein synthesis and cell division. The drug also has antiangiogenic effects, which are thought to contribute to its antitumor activity.</p>
    Formule :C9H12FN3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :245.21 g/mol

    Ref: 3D-ND04700

    10g
    254,00€
    25g
    477,00€
    50g
    679,00€
    100g
    965,00€
  • 2'-Deoxy-3,5-dimethylcytidine

    CAS :
    <p>2'-Deoxy-3,5-dimethylcytidine is a nucleoside analog that is an activator of the ribonucleotide reductase enzyme. It has been shown to have anticancer properties in vitro and in vivo. 2'-Deoxy-3,5-dimethylcytidine has also been shown to be effective against HIV and herpes virus infections. 2'-Deoxy-3,5-dimethylcytidine is synthesized from deoxyribonucleosides or nucleosides by phosphitylation with phosphoramidites or diphosphates. The CAS number for this product is 198198-29-7.</p>
    Formule :C11H17N3O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :255.27 g/mol

    Ref: 3D-ND159352

    1g
    11.065,00€
    100mg
    3.622,00€
    250mg
    5.367,00€
    500mg
    7.382,00€
  • 5'-O-DMT-2'-O-hexylphthalimidouridine


    <p>5'-O-DMT-2'-O-hexylphthalimidouridine is a novel nucleoside analog with anticancer activity. It is a modified nucleoside that has been synthesized and purified in high purity. 5'-O-DMT-2'-O-hexylphthalimidouridine is an activator of DNA and RNA synthesis and has antiviral properties. It also inhibits the production of tumor necrosis factor alpha (TNFα) by human synovial cells. This compound binds to the RNA polymerase II enzyme, which prevents transcription of genetic material from DNA templates into messenger RNA. This leads to inhibition of protein synthesis and cell death by apoptosis.</p>
    Formule :C44H45N3O10
    Degré de pureté :Min. 95%
    Masse moléculaire :775.86 g/mol

    Ref: 3D-ND08415

    50mg
    135,00€
    100mg
    305,00€
  • 2'-O-Methylcytidine

    CAS :
    <p>2'-O-Methylcytidine is a nucleoside with a hydroxyl group on the 2' carbon. The hydroxyl group makes it an effective inhibitor of viral replication, and it has been shown to be active against HIV-1 in cell culture. 2'-O-Methylcytidine is also metabolized by nucleotide salvage pathways, and the metabolic response can be studied using proton nuclear magnetic resonance (NMR) spectroscopy and x-ray diffraction data. It has been found that 2'-O-Methylcytidine inhibits protein synthesis in cancer cells, and this may be due to its ability to bind to the response element on DNA.</p>
    Formule :C10H15N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :257.24 g/mol

    Ref: 3D-NM06302

    5g
    406,00€
    10g
    634,00€
    25g
    1.130,00€
    50g
    1.941,00€
    100g
    3.468,00€
  • β-Nicotinamide adenine dinucleotide sodium dihydrate

    CAS :
    <p>Coenzyme and regenerating electron donor in catabolic processes</p>
    Formule :C21H26N7NaO14P2•(H2O)2
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :721.44 g/mol

    Ref: 3D-NN44827

    5g
    334,00€
    10g
    450,00€
    25g
    863,00€
    50g
    1.356,00€
  • 4-Hydroxy-6-methylpyrimidine

    CAS :
    <p>4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.</p>
    Formule :C5H6N2O
    Degré de pureté :Min. 95%
    Masse moléculaire :110.11 g/mol

    Ref: 3D-NH66985

    2g
    135,00€
    5g
    149,00€
    10g
    203,00€
  • N2,N2,7-Trimethylguanosine

    CAS :
    <p>Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.</p>
    Formule :C13H20N5O5
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :326.33 g/mol

    Ref: 3D-NT08918

    3mg
    981,00€
    8mg
    2.291,00€
    16mg
    4.208,00€
    24mg
    5.214,00€
    1500µg
    565,00€
  • L-Cytidine

    CAS :
    <p>L-Cytidine is a nucleoside that is found in the body, and is also used as a drug. It is a precursor to other nucleosides, such as cytidine triphosphate, which is involved in DNA synthesis and repair. L-Cytidine has been shown to be effective against HIV infection by inhibiting the activity of the enzyme ns3 protease. This inhibition prevents viral proteins from being released from cells and infecting other cells. L-Cytidine has also been shown to be an inhibitor of creatine kinase and glycosidation, two enzymes that are necessary for cell metabolism. L-Cytidine has also been shown to be reactive with halides, which may lead to unwanted side effects.</p>
    Formule :C9H13N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :243.22 g/mol

    Ref: 3D-NC02628

    5g
    305,00€
    10g
    477,00€
    25g
    713,00€
    50g
    1.061,00€
    100g
    1.971,00€
  • N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine

    CAS :
    <p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>
    Formule :C20H23N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :429.43 g/mol

    Ref: 3D-NB144560

    1g
    272,00€
    2g
    391,00€
    5g
    668,00€
    10g
    1.013,00€
  • 2'-Deoxy-5'-O-DMT-cytidine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.</p>
    Formule :C30H31N3O6
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :529.58 g/mol

    Ref: 3D-ND57360

    1g
    254,00€
    250mg
    135,00€
    500mg
    178,00€
  • 1-(α-D-Ribofuranosyl)uracil

    CAS :
    <p>1-(α-D-Ribofuranosyl)uracil is a nucleoside analog made up of a uracil attached to a ribose sugar at the 1-position, with the sugar in the α configuration. This compound is of interest in biochemistry research and nucleoside chemistry, especially when studying stereochemistry or synthesizing analogs.</p>
    Formule :C9H12N2O6
    Degré de pureté :(¹H-Nmr) Min. 95 Area-%
    Couleur et forme :Powder
    Masse moléculaire :244.2 g/mol

    Ref: 3D-NR31832

    1g
    1.213,00€
    50mg
    183,00€
    100mg
    305,00€
    250mg
    509,00€
    500mg
    804,00€
  • 2',3'-Dideoxyinosine

    CAS :
    <p>2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversion</p>
    Formule :C10H12N4O3
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :236.23 g/mol

    Ref: 3D-ND02929

    5g
    305,00€
    10g
    496,00€
    25g
    965,00€
  • Uridine 5'-monophosphate disodium

    CAS :
    <p>Uridine 5'-monophosphate disodium salt (UDP-MS) is a structural analog of uridine that is used as a dietary supplement. It has been shown to inhibit phosphodiesterases and cyclic nucleotide phosphodiesterases, which are enzymes that degrade the secondary messenger, cyclic adenosine monophosphate (cAMP). This inhibition leads to increased levels of cAMP in cells, which stimulates protein kinase A activity and promotes cellular differentiation. The analysis of UDP-MS has been performed using liquid chromatography with ultraviolet detection.</p>
    Formule :C9H11N2Na2O9P
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :368.15 g/mol

    Ref: 3D-NU02983

    1kg
    571,00€
    2kg
    1.022,00€
    5kg
    1.416,00€
    250g
    304,00€
    500g
    428,00€
  • 2'-Deoxy-5-formylcytidine

    CAS :
    <p>2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.<br>2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc</p>
    Formule :C10H13N3O5
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :255.23 g/mol

    Ref: 3D-ND63556

    5mg
    441,00€
    10mg
    560,00€
    25mg
    845,00€
  • 7-Deaza-2'-deoxyxanthosine

    CAS :
    <p>7-Deaza-2'-deoxyxanthosine is an oligodeoxynucleotide that is a substrate for the enzyme dUTPase. The allyl group on 7-deaza-2'-deoxyxanthosine is used to attach it to the 3' end of DNA, where it acts as a competitive inhibitor of RNA synthesis. The ethyl group at the end of the molecule is used to attach it to the 5' end of DNA, where it inhibits transcription and replication by binding with RNA polymerase. 7-Deaza-2'-deoxyxanthosine has been shown to be effective in preventing stenosis following coronary bypass surgery, as well as in treating heart disease by reducing levels of xanthosine.</p>
    Formule :C11H13N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Beige Powder
    Masse moléculaire :267.24 g/mol

    Ref: 3D-ND02491

    25mg
    305,00€
    50mg
    477,00€
    100mg
    679,00€
  • Uridine 5'-diphosphate choline ammonium

    CAS :
    <p>Uridine 5'-diphosphate choline ammonium salt is a chemical compound that contains two molecules of uridine and one molecule of choline. It is a hexamer with an empirical formula of C6H14N4O13P3. Uridine 5'-diphosphate choline ammonium salt can be found in plants and animals, as well as being synthesized by the human body. This compound is present in the interstitium, which are the spaces between cells, and may play a role in the nutritional status of humans.</p>
    Formule :C14H28N4O12P2
    Degré de pureté :Min. 90 Area-%
    Couleur et forme :Powder
    Masse moléculaire :506.34 g/mol

    Ref: 3D-NU16887

    1mg
    254,00€
    2mg
    363,00€
    5mg
    637,00€
    10mg
    1.045,00€
    25mg
    1.970,00€
  • 2'-Deoxy-2'-fluoroinosine

    CAS :
    <p>2'-Deoxy-2'-fluoroinosine is a modified nucleoside analog derived from inosine, where the 2' hydroxyl group of the sugar (normally present in ribonucleosides) is replaced with a fluorine atom, and the molecule contains a deoxyribose sugar.</p>
    Formule :C10H11FN4O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :270.22 g/mol

    Ref: 3D-ND06005

    1g
    471,00€
    2g
    798,00€
    5g
    1.499,00€
    10g
    2.499,00€
    500mg
    313,00€
  • 2,4,6-Trichloro-5-methylpyrimidine

    CAS :
    <p>2,4,6-Trichloro-5-methylpyrimidine is a nucleoside for use in research applications</p>
    Formule :C5H3Cl3N2
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :197.45 g/mol

    Ref: 3D-NT67801

    10g
    135,00€
    25g
    208,00€
    50g
    343,00€