
Nucléosides
3569 produits trouvés pour "Nucléosides"
2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å
2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.
Degré de pureté :Min. 95%3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine
3'-Amino-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine is a novel 3'-amino nucleoside
Formule :C37H36N4O6Degré de pureté :Min. 95%Masse moléculaire :632.71 g/mol6-Chloropurine-9-b-D-glucoside
CAS :6-Chloropurine-9-b-D-glucoside is a nucleoside that belongs to the family of modified nucleosides. It is used as an activator and a phosphoramidate in the synthesis of oligonucleotides. 6-Chloropurine-9-b-D-glucoside is also used in anticancer therapy because it inhibits DNA, RNA, and protein synthesis. 6CPG has antiviral activity against herpes virus and other viruses. This compound has been shown to have antiinflammatory activities by inhibiting the production of prostaglandins. 6CPG is also classified as a carcinogen by the International Agency for Research on Cancer (IARC).
Formule :C11H13CIN4O5Degré de pureté :Min. 95%Masse moléculaire :420.16 g/molAbacavir carboxylate
CAS :Abacavir carboxylate is a prodrug of abacavir that is activated by the carboxylation of the terminal hydroxyl group in the liver. It has been shown to be quantified using a liquid chromatography-mass spectrometry (LC-MS) method. Abacavir carboxylate has an additional benefit of being less sensitive to degradation by nitrate, which can interfere with the analysis of acyclovir. The deuterium label on abacavir carboxylate ensures that it is not confused with acyclovir and facilitates identification in wastewater samples.
Formule :C14H16N6O2Degré de pureté :Min. 95%Masse moléculaire :300.32 g/mol3'-Deoxyadenosine CPG
3'-Deoxyadenosine CPG is a nucleoside that is synthetically manufactured. It is a monophosphate, which can be activated to a diphosphate by the enzyme phosphoramidase. 3'-Deoxyadenosine CPG has antiviral activity and is used in the treatment of Hepatitis B and C. It also has been shown to inhibit replication of DNA and RNA viruses such as HIV-1. 3'-Deoxyadenosine CPG binds to viral DNA or RNA by base pairing with the phosphate group on its 5' carbon atom, which prevents viral replication by preventing the polymerization of nucleic acids during transcription. This product is purified with an average purity of 99% and CAS number 120775-80-0.br>br>
3'-Deoxyadenosine CPG (3'-DAD) is a modified nucleoside that was synthesized for use in antiviral therapy against hepatitis B virusDegré de pureté :Min. 95%Myristoyl coenzyme A lithium salt
CAS :Myristoyl coenzyme A lithium salt is an activator that can be used in the synthesis of Ribonucleosides and Deoxyribonucleosides. It has a high purity, which ensures high quality synthesis. Myristoyl coenzyme A lithium salt is a novel nucleotide precursor that can be used to synthesize DNA or RNA for use in anti-cancer or antiviral treatments.
Formule :C35H62N7O17P3S·xLiDegré de pureté :Min. 95%Masse moléculaire :977.89 g/mol5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine
5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue. It has antiviral activity and can be used to treat infections caused by herpes virus. It also has anticancer activity against some types of cancer cells and can inhibit the growth of tumour cells. 5'-O-DMT-thymidine 3'-Rp-oxazaphospholidine acts as an inhibitor of DNA polymerase, preventing the synthesis of DNA from RNA. It also inhibits ribonucleotide reductase, which is involved in the production of ribonucleotides from diphosphate nucleotides. This drug can be used as a monophosphate or phosphoramidite for the synthesis of oligodeoxyribonucleotides and deoxyribonucleotides.
Degré de pureté :Min. 95%cis-Zeatin-o-glucoside riboside
CAS :Cis-Zeatin-o-glucoside riboside is a plant metabolite that belongs to the class of phenylpropanoids. It is the product of the conversion of zeatin by a polyphenol oxidase. Cis-Zeatin-o-glucoside riboside has been found in plants, such as Eucomis and Alnifolia, at levels ranging from 0.2 to 1%. This metabolite is also present in animal tissues, such as rat brain and bovine mammary gland. The metabolic pathway for cis-Zeatin-o-glucoside riboside has been elucidated through tissue culture experiments with Eucomis and 24-epibrassinolide. The biosynthesis of this metabolite involves a two step process: first, an oxidative cleavage of zeatin to indole-3-acetyl l -aspartic acid and then conversion to
Formule :C21H31N5O10Degré de pureté :Min. 95%Masse moléculaire :513.5 g/mol5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione
Ribonuclease is an enzyme that cleaves the phosphodiester backbone of ribonucleotide to produce a 5'-phosphate and a 2'-deoxyribonucleoside. Ribonuclease is an activator that activates the synthesis of ribonucleotides, deoxyribonesucleotides and nucleosides. Ribonuclease has antiviral properties which may be due to its ability to inhibit DNA polymerase by catalyzing the hydrolysis of the 2'-deoxyribose-5'-phosphate bond in DNA. Ribonuclease has also been shown to have anticancer activity, which may be due to its ability to inhibit protein synthesis.
Degré de pureté :Min. 95%2-Methylthio-6-chloropurine
CAS :2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.
Formule :C6H5CIN4SDegré de pureté :Min. 95%Masse moléculaire :304.11 g/mol5′-O-DMT-LNA N-dmf guanosine
CAS :5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.
Formule :C35H36N6O7Degré de pureté :Min. 95%Masse moléculaire :652.7 g/mol2'-Deoxy-2',2'-difluoroguanosine
CAS :2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.
Formule :C10H11F2N5O4Degré de pureté :Min. 95%Masse moléculaire :303.22 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine
CAS :E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine is a monophosphate nucleoside analog that has been modified to be resistant to antiviral ribonucleases. This drug is phosphorylated in vivo to the corresponding diphosphate and triphosphate, which inhibits viral DNA synthesis and thus prevents the virus from replicating. E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine can be used as an antiviral agent against herpes simplex virus (HSV).Formule :C34H34N2O9Degré de pureté :Min. 95%Masse moléculaire :614.66 g/molLinoleoyl coenzyme A
CAS :Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.
Formule :C39H66N7O17P3SDegré de pureté :Min. 95%Masse moléculaire :1,029.97 g/mol2′-O-Succinyladenosine 3′,5′-monophosphate
CAS :Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C14H16N5O9PDegré de pureté :Min. 95%Masse moléculaire :429.28 g/mol2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine
CAS :2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine (dAraMP) is a novel nucleoside analogue that was synthesized and characterized. It has been shown to inhibit the growth of cancer cells in vitro. dAraMP is a monophosphate analogue of 2,6-diamino-9-(2'-deoxy-b-D-ribofuranosyl)purine (dAraP). The modified phosphoramidite approach used in its synthesis yielded high purity and yields. This product is also available as a diphosphate analogue of 2,6 diamino 9-(2'-amino 2'-deoxy b D ribofuranosyl) purine (dAMP). The diphosphate form of this product has been shown to be an activator for DNA polymerase.Formule :C10H15N7O3Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :281.28 g/mol3',5'-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-o-methyluridine
CAS :3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a novel monophosphate nucleoside analog that is activated by T4 polynucleotide kinase. It is synthesized from the corresponding phosphoramidite and reacts with the 5'-OH group of a ribonucleoside to form a 3',5'-di-O-acetylribonucleoside. The diacetyl group confers increased stability to the molecule and also provides an acetyl group for incorporation into DNA. This compound has antiviral activity against herpes simplex virus type 1 (HSV1) in cell culture and has shown anticancer properties in animal studies.
Formule :C23H27FN2O8Degré de pureté :Min. 95%Masse moléculaire :478.5 g/molN6-Acetyl-2'-deoxy-5'-O-DMT-adenosine
N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.
Formule :C33H33N5O6Degré de pureté :Min. 95%Masse moléculaire :595.65 g/mol5'-Cytidylic acid
CAS :Please enquire for more information about 5'-Cytidylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C9H14N3O8PDegré de pureté :Min. 98.0 Area-%Masse moléculaire :323.20 g/molThymidine-a,a,a,6-D4
CAS :Produit contrôléThymidine-a,a,a,6-D4 is a nucleoside analogue that inhibits the replication of the hepatitis B virus. It is an analogue of thymidine and is activated by phosphorylation to its active form. This drug prevents viral replication by inhibiting early events in the viral life cycle. Thymidine-a,a,a,6-D4 has been shown to inhibit the synthesis of viral DNA and to inhibit the incorporation of thymidine into newly synthesized DNA. Thymidine-a,a,a,6-D4 also inhibits telbivudine resistance mutations in vitro.
Formule :C10H10N2O5D4Degré de pureté :Min. 95%Masse moléculaire :246.25 g/mol2-Hydroxyaminoadenosine
CAS :2-Hydroxyaminoadenosine (2-HAA) is a novel nucleoside that is used as an activator of ribonucleotide reductase. It has been shown to be effective against cancer cells in vitro and in vivo. 2-HAA also inhibits the synthesis of viral DNA, which may be due to its ability to inhibit the ribonuclease activity of the virus. 2-HAA has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1).
Formule :C10H14N6O5Degré de pureté :Min. 95%Masse moléculaire :298.26 g/molLauroyl coenzyme A
CAS :Lauroyl CoA is a body-fat molecule that can be formed from acetyl-coenzyme A, which is an intermediate in the metabolism of fatty acids. It is used in analysis as a standard for enzyme activities and as a substrate for reactions involving enzymes with coenzyme A. Reaction mechanisms are determined using titration calorimetry and structural analyses are performed using analytical methods such as infrared spectroscopy and nuclear magnetic resonance spectroscopy. Lauroyl CoA is also used to study the effects of the protein toll-like receptor 4 on hepatic steatosis. The wild-type strain of Escherichia coli was used to measure the activity of bacterial synthetases containing lauroyl CoA.
Formule :C33H58N7O17P3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :949.84 g/mol6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt
CAS :6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it canFormule :C17H16N5Na2O9PSDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :543.36 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS :3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (BUdR) is an antiviral agent that is used in the synthesis of DNA and RNA. BUdR is a modified phosphoramidite that is activated with diphosphate. It has a high quality, high purity, and a novel structure. BUdR has been shown to have anticancer properties as well as inhibitory effects on HIV production in cells.
Formule :C16H27N5O4SiDegré de pureté :Min. 95%Masse moléculaire :381.51 g/mol2-Pyridin-2-ylpyrimidine-5-carbaldehyde
CAS :Ribonucleosides and deoxyribonucleosides are synthetic analogues of the natural nucleotides. Ribonucleosides are analogues of ribose and deoxyribonucleosides are analogues of deoxyribose. Ribonuclesides, Deoxyribonucleosides, Activator, Antiviral, Synthetic, Modified, DNA, Nucleosides is a novel nucleotide analogue with high quality and purity. It can be used in the synthesis of oligodeoxynucleotides for use as antiviral agents. It is also a component of phosphoramidites.Formule :C10H7N3ODegré de pureté :Min. 95%Masse moléculaire :185.18 g/mol7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS :7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.
Formule :C14H14ClN3Degré de pureté :Min. 95%Masse moléculaire :259.73 g/molInosine-3',5'-cyclic-monophosphate sodium
CAS :Inosine-3',5'-cyclic-monophosphate sodium (cIMP) is a metabolite of inosine and is generated by the enzyme inosine monophosphate cyclohydrolase. cIMP has been shown to be related to colorectal adenocarcinoma, cancer, and body mass index. It has also been implicated in the diagnosis of cancer and infectious diseases. cIMP is involved in energy metabolism and DNA synthesis, which are important for the progression of renal cell cancer. In addition, it has been shown that cIMP can function as a biomarker for prognosis when used with multivariate logistic regression.Formule :C10H11N4O7P·NaDegré de pureté :Min. 95%Masse moléculaire :353.18 g/mol3'-Deoxy-3',4'-didehydro-CTP
CAS :3'-Deoxy-3',4'-didehydro-CTP is a nucleoside analog. It is a novel, high quality, high purity and synthetic compound with antiviral and anticancer activities. 3'-Deoxy-3',4'-didehydro-CTP inhibits the synthesis of DNA by specifically inhibiting the activity of DNA polymerase. The IC50 value for this compound is 12.5 μM against herpes simplex virus type 1 (HSV-1) in vitro.
Formule :C9H14N3O13P3Degré de pureté :Min. 95%Masse moléculaire :465.14 g/mol8-(p-Chlorophenylthio)-cGMP
CAS :8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.
Formule :C16H15ClN5O7PSDegré de pureté :Min. 95%Masse moléculaire :487.81 g/mol2-(2-Cyclohexylethoxy)adenosine
CAS :2-(2-Cyclohexylethoxy)adenosine (CX-5461) is a new chemical entity that has been shown to have an incremental effect on muscle contraction. The mechanism of action of CX-5461 is not fully understood, but it has been shown to be nonselective and to bind to adenosine receptors. This binding produces a response in the cell similar to that of adenosine, which is a small molecule involved in the regulation of blood pressure and heart rate. CX-5461 also binds with platelet membranes at the site of inflammation and causes vasodilation. It has been shown to be effective in animal models of pertussis, where it reduces the severity of muscle spasms and increases the duration before death. These effects are due to CX-5461's ability to lower intracellular calcium concentrations by preventing calcium release from internal stores or from outside sources such as muscle cells or platelets.
Formule :C18H27N5O5Degré de pureté :Min. 95%Masse moléculaire :393.44 g/mol5'-O-DMT-2,2'-anhydrouridine
CAS :5'-O-DMT-2,2'-anhydrouridine is a nucleoside that is an activator of RNA polymerase. This compound is novel and can be used for the synthesis of modified oligonucleotides and DNA. 5'-O-DMT-2,2'-anhydrouridine has anticancer properties and can be used in the treatment of cancer. 5'-O-DMT-2,2'-anhydrouridine has been shown to inhibit the growth of cancer cells by binding to DNA and inhibiting the production of RNA.
Formule :C30H28N2O7Degré de pureté :Min. 95%Masse moléculaire :528.55 g/mol3'-O-Methyl-5'-guanylic acid
CAS :3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.
Formule :C11H16N5O8PDegré de pureté :Min. 95%Masse moléculaire :377.25 g/molN1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester
CAS :N1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester is a novel nucleoside analogue and phosphoramidite. It has been modified to have an acyclic carbon chain with a 4-hydroxybenzoyl group at the C2 position. This compound is an activator of DNA synthesis, and it can be used for the synthesis of deoxyribonucleosides. The purity of this compound is 99%. The CAS number for this compound is 869354-61-0.
Formule :C27H31N3O6SDegré de pureté :Min. 95%Masse moléculaire :525.6 g/mol3'-O-tert-Butyldimethylsilyladenosine
CAS :3'-O-tert-Butyldimethylsilyladenosine is a synthetic nucleoside that is an antiviral agent with high purity. It has been shown to have anticancer properties and can be used as a deoxyribonucleoside activator or as a novel monophosphate nucleoside. 3'-O-tert-Butyldimethylsilyladenosine is also modified with an alkyl group for the phosphoramidite building block synthesis of DNA, RNA, and oligonucleotides. It has been shown to inhibit the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase in cells.Degré de pureté :Min. 95%2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt
2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt is an activator that has been synthesized for therapeutic use. It is a modified nucleoside, which means that it does not occur naturally in the human body and must be made artificially. This drug is currently undergoing clinical trials and is being studied for its anticancer properties. 2'-O-Methyladenosine-5'-a-thiotriphosphate sodium salt binds to the phosphate groups on DNA and inhibits viral replication by preventing RNA synthesis. It also has antiviral activity against Herpes simplex virus type 1, HIV type 1, and influenza A virus type H1N1. The drug may have potential as a treatment for chronic hepatitis B infection as well as various cancers such as breast cancer, prostate cancer, and leukemia.
Degré de pureté :Min. 95%DdCTP trilithium
CAS :2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon
Formule :C9H13N3Li3O12P3Degré de pureté :Min. 95%Couleur et forme :LiquidMasse moléculaire :468.96 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-2'-(p-nitrophenylcarbonyloxy)uridine
CAS :3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-2'-(p-nitrophenylcarbonyloxy)uridine is a novel phosphoramidite. It is modified with p-nitrophenyl carbonyloxy group at the 3' position of the uracil moiety. This phosphoramidite has antiviral activity against Hepatitis C and HIV. It also has anticancer activity in vitro and in vivo. 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-2'-(p-nitrophenylcarbonyloxy)uridine is a nucleoside that can be used for DNA synthesis or as a monophosphate or diphosphate for RNA synthesis. It is synthesized from deoxyFormule :C28H41N3O11Si2Degré de pureté :Min. 95%Masse moléculaire :651.81 g/molNPOM-Caged-dT CEP
CAS :Please enquire for more information about NPOM-Caged-dT CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C50H58N5O13PDegré de pureté :Min. 95%Masse moléculaire :968 g/mol2',3'-O-Isopropylidene-6-thioinosine
CAS :2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.
2',3'-O-Isopropylidene-6-thioinosFormule :C13H16N4O4SDegré de pureté :Min. 95%Masse moléculaire :324.36 g/molUridine-2-13C
CAS :Uridine-2-13C is a modified nucleoside that is used as an anticancer agent. It is phosphorylated to uridine-2-13C diphosphate and can be used in DNA synthesis and as a radiolabel.
Formule :C9H12N2O6Degré de pureté :Min. 95%Masse moléculaire :245.19 g/mol2'-Deoxy-5'-O-DMT-adenosine
CAS :2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.
Formule :C31H31N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :553.61 g/mol3'-O-Azidomethyl 2'-deoxythymidine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxythymidine 5'-O-triphosphate sodium salt is a nucleoside that inhibits the replication of DNA and RNA. It has antiviral activity against influenza A and herpes simplex virus, as well as anticancer activity.
Degré de pureté :Min. 95%3',5'-Diamino-3',5'-dideoxyadenosine
CAS :3',5'-Diamino-3',5'-dideoxyadenosine (3,5-ddA) is a nucleoside that has been shown to be an efficient inhibitor of HIV replication in vitro. It has been used for the treatment of AIDS, but it is not yet approved for this use. 3,5-ddA inhibits the conversion of dATP to dTTP and prevents DNA synthesis by blocking the enzyme ribonucleotide reductase. The drug can be synthesized with high efficiency by using a modified nucleoside amidite approach.
Formule :C10H15N7O2Degré de pureté :Min. 95%Masse moléculaire :265.28 g/molN4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine
N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine is an antiviral drug that inhibits viral DNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. It is a nucleoside analog that is used for the treatment of cancer and for the prevention of AIDS. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5 -iodocytidine is synthesized in high purity, with a purity level of > 98%. This product can be used as an activator or ligand in phosphoramidite synthesis.Formule :C22H30IN3O5SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :571.48 g/mol5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine
5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is an activated nucleoside phosphoramidite for the synthesis of DNA and RNA. It is a building block for various nucleic acid analogues and has been shown to have antiviral and anticancer properties. 5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is also known as N6 -(2,4,6 trimethoxybenzoyl) adenosine or 5'-O-(2,4,6 triisopropoxybenzoyl)-adenosine (TIBA) and is used in the laboratory to produce oligonucleotides with modified sugar groups. This product has been shown to be effective against a number of cancer cell lines and has potential use in chemotherapy.
Formule :C45H47N3O10Degré de pureté :Min. 95%Masse moléculaire :789.89 g/mol5'-O-DMT-3'-O-hexylphthalimidouridine
5'-O-DMT-3'-O-hexylphthalimidouridine is an antiviral and anticancer agent that is a nucleoside analog. It inhibits viral replication by preventing the production of RNA, which is necessary for the synthesis of DNA. It also prevents the proliferation of cancer cells and induces apoptosis by inhibiting DNA synthesis. 5'-O-DMT-3'-O-hexylphthalimidouridine is a monophosphate that has been modified to form a phosphoramidite. The synthesized product was purified to high purity and quality with a novel structure.
Formule :C44H45N3O10Degré de pureté :Min. 95%Masse moléculaire :775.86 g/mol5-Azauridine
CAS :5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.
Formule :C8H11N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :245.19 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite
CAS :A 5'-3’ “reverse” (or “inverse”) amidites
Formule :C47H52N7O7PDegré de pureté :Min. 95%Masse moléculaire :857.93 g/mol2'-Deoxy-4'-ethynyl-2-fluoroadenosine
CAS :2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long
Formule :C12H12FN5O3Degré de pureté :Min. 95%Masse moléculaire :293.25 g/mol5'-O-Tosylthymidine
CAS :5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Formule :C17H20N2O7SDegré de pureté :Min. 95%Masse moléculaire :396.42 g/molN2-Benzoylguanosine
CAS :N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.
Formule :C17H17N5O6Degré de pureté :Min. 95%Couleur et forme :White to beige solid.Masse moléculaire :387.35 g/mol2',3',5'-Tri-O-acetylinosine
CAS :2′,3′,5′-Tri-O-acetylinosine is a protected form of the nucleoside inosine, with potential for use in the preparation of modified nucleotides and nucleoside analogs.
Formule :C16H18N4O8Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :394.34 g/molSpacer-c3 cep
CAS :Spacer-C3 Cep is a novel modified nucleoside phosphoramidite. It has been chemically modified with a spacer arm and 3-Cep (1,2-diaminoethane). Spacer-C3 Cep is an activator for DNA polymerases, which are enzymes that synthesize DNA from deoxyribonucleosides. The modified nucleoside phosphoramidite has antiviral and anticancer activities. It can be used in the synthesis of oligodeoxyribonucleotides for gene therapy or as a monophosphate for the preparation of DNA probes. Spacer-C3 Cep can also be used to synthesize ribonucleotide analogs that inhibit viral replication by inhibiting RNA synthesis.
Formule :C33H43N2O5PDegré de pureté :Min. 95%Masse moléculaire :578.7 g/mol5-Methyl-L-uridine
CAS :5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.
Formule :C10H14N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :258.23 g/molRef: 3D-NM06240
Produit arrêtéGuanylyl-3',5'-guanosine ammonium salt
CAS :Guanylyl-3',5'-guanosine ammonium salt is a novel antiviral agent that has high antiviral activity against influenza A virus. It is a guanine derivative which has been modified to include an aminopropyl group and an ammonium cation. This compound also acts as an activator for deoxyribonucleosides, nucleotides, and ribonucleosides. Guanylyl-3',5'-guanosine ammonium salt may be used in the manufacture of DNA, RNA, and phosphoramidites. This compound also has anticancer effects by inhibiting the proliferation of tumor cells and inducing apoptosis.
Formule :C20H25N10O12P·H3NDegré de pureté :Min. 95%Masse moléculaire :645.48 g/molRibavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution
CAS :Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.
Formule :C8H15N4O14P3•(C6H15N)xDegré de pureté :Min. 95 Area-%Couleur et forme :Clear LiquidMasse moléculaire :789.733′-Guanylic acid disodium
CAS :3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.
Formule :C10H14N5O8P•Na2Degré de pureté :Min. 95%Masse moléculaire :409.2 g/molAdenosine 5'-monophosphate sodium
CAS :Adenosine 5'-monophosphate sodium is a nucleotide that is involved in the energy metabolism of cells. It has been shown to inhibit oxidative injury and to activate signal pathways in response to external stimuli, such as glucose deprivation. Adenosine 5'-monophosphate sodium can be synthesized from ATP by the enzyme adenosine kinase.
Formule :C10H13N5O7P·NaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :369.2 g/molDMTr-TNA-C(Bz)-amidite
CAS :Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formule :C45H50N5O8PMasse moléculaire :819.9 g/mol2'-Deoxy-a-adenosine
CAS :2'-Deoxy-a-adenosine is a nucleoside that contains an adenine base. It has been studied for its biological properties, including its reaction with solution and its use as an antimicrobial agent. 2'-Deoxy-a-adenosine has been shown to inhibit the growth of bowel disease in mice by binding to the adenosine A3 receptor on the surface of cells. This nucleoside also binds to nuclear DNA and may be used as a pharmacological agent, but more research is needed to determine whether it would be effective against cancer cells. 2'-Deoxy-a-adenosine may also be useful as a potential drug target for the treatment of cancer due to its ability to bind with dna duplexes, which are found in all cancer cells.
Formule :C10H13N5O3Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :251.25 g/mol5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine
CAS :5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine is a nucleoside that is used as an antiviral and anticancer agent. It is a novel compound that has not been previously described in the literature. 5’-O-DMT-2’-O,4’-C methylene 5 methyluridine has been shown to inhibit the replication of the herpes virus in vitro (in cell culture) and in vivo (in animals). This compound also inhibits the proliferation of cancer cells by inhibiting DNA synthesis. It may be used as an anticancer agent or an antiviral agent.
Degré de pureté :Min. 95%5′-O-DMT-LNA N-Bz adenosine
CAS :5′-O-DMT-LNA N-Bz adenosine is a novel nucleoside that has been modified with an aminooxy group. The compound is synthesized by the phosphoramidite method and it is designed for use in antiviral and anticancer research. 5′-O-DMT-LNA N-Bz adenosine can be used as a substrate for DNA polymerases and other enzymes to produce nucleic acid strands. This product is CAS No. 206055-74-5, monophosphate, Phosphoramidites, Synthetic, Deoxyribonucleosides, Anticancer, Ribonuclesides, High purity.
Formule :C39H35N5O7Degré de pureté :Min. 95%Masse moléculaire :685.73 g/mol2',3'-O-Isopropylideneinosine
CAS :2',3'-O-Isopropylideneinosineis a nucleoside for use in research applications
Formule :C13H16N4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.3 g/molRef: 3D-NI03500
Produit arrêté2-Chloroadenosine 5'-monophosphate triethylamine salt
CAS :2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.
Formule :C10H13ClN5O7P·C12H30N2Degré de pureté :Min. 95%Masse moléculaire :584.05 g/mol2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate
CAS :10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position
Degré de pureté :Min. 95%2'-O-Methyluridine-5'-monophosphate triethylammonium
CAS :2'-O-Methyluridine-5'-monophosphate triethylammonium salt is a modified nucleoside analogue that is an antiviral agent. It inhibits viral replication by acting as an inhibitor of RNA synthesis and DNA polymerase, which are necessary for the virus to replicate. This compound also has anticancer activity and can be used as a chemotherapeutic agent. 2'-O-Methyluridine-5'-monophosphate triethylammonium salt is synthesized from uracil, phosphoramidite, and triethylamine. It has high purity and high quality with a CAS number of 67624-43-5.
Formule :C10H15N2O9P•(C6H15N)2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :439.21 g/moldNaM
CAS :dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.
Formule :C16H18O4Degré de pureté :Min. 95%Masse moléculaire :274.31 g/molRef: 3D-SUB89319
Produit arrêté2',3'-Dideoxy-3',5-difluorocytidine
CAS :2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.
Degré de pureté :Min. 95%Archaeosine
CAS :Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.
Formule :C12H16N6O5Degré de pureté :Min. 95%Masse moléculaire :324.29 g/mol
