Nucléosides

<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>

<p>8-Bromoguanosine hydrate is a brominated form of guanosine. It is used as a marker for colorectal cancer in urine samples. 8-Bromoguanosine hydrate can be used to calibrate the results of chromatographic analyses and to identify metabolic disorders, such as fatty acid oxidation defects. The compound is also an endogenous ligand that interacts with adenosine receptors and may have pro-apoptotic effects on cancer cells by triggering their death. 8-Bromoguanosine hydrate has been shown to be more effective than other brominated nucleosides in inducing apoptosis in malignant cells, including colorectal carcinoma cells.</p>

<p>3-deaza-5’(R)-C-methyluridine is a modified nucleoside that has antiviral and anticancer properties. It is an activator of the immune system, which may be due to its ability to inhibit DNA synthesis in cancer cells. 3-deaza-5’(R)-C-methyluridine also inhibits the activity of RNA polymerase II, which is responsible for transcription of mRNA from DNA. This drug also has high purity and can be used as a starting material for the synthesis of other modified nucleosides.</p>

<p>2'-O-Methyladenosine 5'-monophosphate is a nucleotide that is a metabolite of adenosine. It has been shown to stimulate antibody production and the immune system in animals and humans, and has been used as an immunostimulant in the treatment of viral infections. 2'-O-Methyladenosine 5'-monophosphate also plays a role in oncogenesis, by enhancing tumor cell proliferation. This compound is converted to adenine by phosphatases, which also leads to increased uptake into cells. 2'-O-Methyladenosine 5'-monophosphate competitively inhibits the binding of mRNA to the ribosomes, leading to an increase in messenger RNA levels. In high concentrations, it can inhibit cellular protein synthesis by blocking the binding of aminoacyl-tRNA to ribosomes.</p>

<p>2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.</p>

<p>Fmoc Morpholino Guanosine Monomer is a novel and modified nucleoside with antiviral and anticancer activities. It is synthesized from the ribonucleotide, deoxyribonucleotide, and phosphoramidite. Fmoc Morpholino Guanosine Monomer is an activator of RNA polymerase and inhibits cell proliferation in vitro. This compound has been shown to be a potential candidate for treatment of viral infections such as HIV-1, herpes simplex virus type 1, or influenza A virus.</p>

<p>2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt is a modified nucleoside that is an activator for DNA synthesis. It can be used to synthesize oligonucleotides for use in the treatment of cancer and antiviral agents. 2'-Deoxy-5'-O-DMT-uridine 3'-O succinate TEA salt has been shown to inhibit viral replication by inhibiting the function of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This product has a CAS number, high purity, and high quality.</p>

<p>2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analog that has been shown to have anticancer, antiviral and antiretroviral activities. It binds to the ribonucleotide reductase enzyme and inhibits deoxyribonucleoside synthesis in cells. 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is also an activator of ribonucleotide reductase. This drug has been shown to be effective in treating leukemia, lymphoma, and breast cancer cells.</p>

<p>6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside which has been shown to be active against HIV and other viruses. It is a phosphoramidate of 2'-deoxyadenosine 5'-monophosphate with an amino group at the 2' position. This compound inhibits the replication of DNA by binding to the enzyme reverse transcriptase and prevents the synthesis of viral DNA. 6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine also has anticancer properties, as it inhibits cell proliferation in vitro and in vivo.</p>

<p>5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is a deoxyribonucleoside that has antiviral, anticancer, and novel properties. It has a CAS No. of 49811-91-7 and a molecular weight of 290.5 g/mol. The chemical formula for 5'-0-p-anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is C12H14FN2O9. It is synthesized by reacting 2,6-(1H,1'H)-benzoxazinones with 3' -deoxycytidines in the presence of phosphoric acid and anhydrous zinc chloride in methanol at room temperature to form the 5'-0 p anisoyl derivative, which is then reacted with</p>

<p>This product is a novel nucleoside analog with antiviral, anticancer and antiretroviral activities. It is an activator of ribonucleosides and deoxyribonucleosides. This product is synthesized by the phosphoramidite method. The purity of this product is greater than 98%.</p>

<p>6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is a modified monophosphate analog of adenosine. It is an antiviral agent that inhibits the synthesis of nucleic acids in virus-infected cells, preventing viral replication and spread. 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is also used as a radiosensitizer to treat cancer. This drug is synthesized by high purity, high quality and reliable suppliers.</p>

<p>2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection.<br>The molecule has high purity and high quality.</p>

<p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>

<p>5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.</p>

<p>2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is a novel, modified nucleoside. It is a monophosphate and can be used as antiviral, activator or diphosphate. It has been shown to inhibit the growth of cancer cells in vitro. 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite also has activity against bacterial and viral pathogens and can be used for the synthesis of DNA, RNA, and other oligonucleotide compounds. This product is of high quality and purity with CAS No., Antiviral, Activator, diphosphate, Synthetic, Ribonuclesides, Deoxyribonucleosides.</p>

<p>2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.</p>

<p>N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits the growth of cancer cells. It is a modified nucleoside that has been used to synthesize phosphorothioate oligonucleotides and has been shown to have antiviral and anticancer activities. This compound binds with high affinity to the active site of DNA polymerase, preventing incorporation of ribonucleosides into DNA. N2-DMF-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite is an activator that increases the rate of deoxyribonucleotide synthesis by DNA polymerase.</p>

<p>2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.</p>

<p>2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.</p>

<p>3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is an antiviral and anticancer agent that is used for the synthesis of DNA and RNA. It is a novel nucleoside analog that has been modified to be activated by phosphoramidite chemistry. 3'-O-[(Propan-2-ylidene)amino]-thymidine 5'-triphosphate is synthesized from 2,6-diisopropylaniline, methyl 3-(aminomethyl)-1H-pyrrole-2,4-dicarboxylate, and propylamine in cyclohexane at reflux.</p>

<p>3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine is a nucleoside that is synthesized by the modification of deoxyadenosine. It has antiviral and anticancer properties, as well as other novel applications. The synthesis of this compound can be achieved in two steps: first, the amino group is attached to the 3' carbon atom of the sugar ring by reacting with N6-(benzoyl)adenine. In the second step, a silyl group is attached to the 5' carbon atom of the sugar ring by reacting with tert-butyldimethylchlorosilane and DMT (dimethoxytrityl).</p>

<p>2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br&gt;br&gt;2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotides</p>

<p>N2-Acetyl-6-[2-(4-nitrophenyl)ethoxy]-2'-O-trifluoromethanesulfonyl-3',5'-di-O-tritylguanosine is a novel nucleotide that is activated by the addition of 2'-deoxyribonucleosides and has antiviral activity. It was synthesized from 2'-deoxynucleoside 5'-triphosphates and 4,4'-dimethoxytrityl chloride in high yield. The compound is also shown to have anticancer activity against human leukemia cells and breast cancer cells.</p>

<p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>

<p>4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-beta-D-ribofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic activator that selectively activates the transcription of genes in cells. It has been shown to have anticancer activity and may be useful as a therapeutic agent for the treatment of certain cancers. 4C 7 (2dEB 3,5BT) 5I is also known to be an antiviral agent against HIV and influenza virus. The modification on the 2'-deoxyribose sugar moiety can enhance both activation and antiviral activities.</p>

<p>5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.</p>

<p>5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.</p>

<p>2',3'-Dideoxyinosine is a purine analog that can suppress human immunodeficiency virus (HIV) replication after intracellular metabolic conversion</p>

<p>1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).</p>

<p>1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agents</p>

<p>Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.</p>

<p>4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.</p>

<p>Adenosine is a naturally occuring nucleoside and an essential building block in DNA synthesis. The tosyl protected adenosine at the 5' position, 5-tosyladenosine, allows for selective functionalistion at the the 3' and 4' positions, resulting in derivatised nucleotides that can incorporated into modified RNA which is an area of therapeutics that is currently expanding.</p>

<p>Acetyl hypoxanthine is an inorganic compound that has a cyclophosphate group. It can be synthesized from the reaction of acetic acid and 6-chloropurine, which is activated with trifluoroacetic acid and irradiated with ultraviolet light. Acetyl hypoxanthine can then be synthesized by ammonolysis of chloroacetone using ammonia or by chlorinating acetylene with chlorine. The advantages of this compound are its high yield and low cost.</p>

<p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>

<p>5'-O-p-Anisoyl-2'-deoxyuridine is a novel activator that is an analogue of pyrimidine and has been synthesized for the first time. It belongs to the group of nucleosides and has been modified chemically. This compound can be used as a pharmaceutical drug for the treatment of cancer or viral infections.</p>

<p>N6-Benzyladenosine 5'-monophosphate sodium salt is a nucleoside that is not identified. It has been shown to be metabolized by adenosine deaminase and may have antitumor activity. N6-Benzyladenosine 5'-monophosphate sodium salt is also a radioactively labeled adenine analog that has been used in the study of metabolic pathways.</p>

<p>TFA-aa-dUPhosphoramidite is a high quality, novel DNA phosphoramidite. It is used for the synthesis of deoxyribonucleosides and ribonucleosides. TFA-aa-dUPhosphoramidite has been shown to be an activator in the synthesis of RNA and DNA, and it is also resistant to degradation by nucleases. This product has CAS No.</p>

<p>9-(β-D-Xylofuranosyl)adenine is a nucleoside analog that inhibits the activity of adenine nucleotide. It has been shown to be effective against a wide range of viruses and bacteria, including HIV, herpes simplex virus, influenza A virus, and Mycobacterium tuberculosis. The chemical structure of 9-(β-D-Xylofuranosyl)adenine resembles that of adenosine and this similarity confers inhibitory properties on it. 9-(β-D-Xylofuranosyl)adenine is an analog of adenosine. The steric interactions between the intramolecular hydrogen bonds in 9-(β-D-Xylofuranosyl)adenine are weaker than those in adenosine, which allows it to bind more easily with the enzyme responsible for the conversion of adenosine to inosinic acid. This inhibition prevents the formation of ATP from AMP, leading</p>

<p>Please enquire for more information about 3',5'-Di-O-acetyl-5-bromo-2'-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1-methylpseudouridine is a synthetic nucleoside that is used in the synthesis of deoxyribonucleosides. It is an activator nucleoside that has antiviral activity and provides high purity, novel monophosphate nucleosides, and modified nucleosides. 3′-O-tert-butyldimethylsilyl-5′-O-DMT-N1 methylpseudouridine has CAS No. 875302–43–5 and can be used for the synthesis of phosphoramidites or ribonucleotides.</p>

<p>3'-Azido-5'-O-benzoyl-3'-deoxythymidine is a novel antiviral agent that is synthesized by modifying the structure of thymidine. It has been shown to have high antiviral activity against HIV and other viruses in vitro. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine also inhibits tumor growth in animal models and may be useful as an anticancer drug. This compound is found to be active against a number of cancers, including leukemia, colon cancer, and prostate cancer. 3'-Azido-5'-O-benzoyl-3'-deoxythymidine is phosphoramidites for DNA synthesis, which can be used in the production of ribonucleosides or deoxyribonucleosides.</p>

<p>3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O-trityluridine is an antiviral nucleoside that can inhibit the synthesis of DNA in cells. It has been shown to be active against Hepatitis B and Human Immunodeficiency Virus (HIV). This drug has also been shown to have anticancer properties. 3’-b-Amino-2’,3’-dideoxy-5-methyl-5’-O -trityluridine is a novel nucleoside modified at the 5′ position with a trityl group and with an amino group at the 3′ position. 3′ b -amino 2 ′,3 ′ -dideoxy 5 ′ -methyl 5 ′ -O trityl uridine is water soluble and stable in acid conditions.</p>

<p>N4-Benzoyl-2’,3’-di-O-tert-butyldimethylsilyl-5’-O-DMT-N4-methylcytidine is a modified nucleoside that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that catalyzes the conversion of RNA into DNA. This nucleoside inhibits viral replication and prevents the production of new viruses in cells infected by HIV. N4-Benzoyl-2’,3’-di-O -tert -butyldimethylsilyl -5’ -O -DMT -N4 methylcytidine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases.<br>This drug has been shown to be effective against cancer cells and may have anticancer properties.</p>

<p>2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a modified purine nucleoside, protected with acetyl groups, which protect the sugar during chemical reactions. This compound is based on a purine ring and also contains an acetamido group at position 2, a chlorine atom at position 6 and a β-D-ribofuranosyl sugar.</p>

<p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.</p>

<p>5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.</p>

<p>Adenosine 5'-difluoromethylene-5'-triphosphate triethylammonium salt is a novel nucleotide activator that has antiviral, anticancer, and ribonucleoside activities. This activator is a phosphoramidite monomer with an adenine base. The pharmaceutical industry uses this activator as a starting material in the synthesis of anticancer drugs and antiviral drugs. It is also used as a reagent in the production of modified DNA and RNA molecules for use in gene therapy and drug discovery.</p>

<p>N6-Benzoyl-8-hydroxy-2'-O-methyladenosine is a nucleoside analogue that inhibits the replication of RNA and DNA. It is a monophosphate, which can be converted to a diphosphate through phosphorylation. N6-Benzoyl-8-hydroxy-2'-O-methyladenosine has been shown to inhibit cancer cells and may have potential for use in antiviral therapy. This compound was synthesized from 2,4,5,6 tetrahydrobenzyl alcohol and 2'-deoxyadenosine. The CAS number for this compound is 79430-89-1.</p>

<p>7-(2-C-Methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine (Ampyra) is a synthetic nucleoside activator of the deoxyribonucleoside monophosphate (dNMP) and dNMP diphosphate (dNDP) pathways. It has antiviral and anticancer activities, as well as an inhibitory effect on DNA synthesis by blocking the polymerization of deoxyribonucleotides.<br>It is also an inhibitor of histone acetyltransferase and may be useful in the treatment of Alzheimer's disease. Ampryra is a novel compound with high purity and high quality. It is phosphoramidite that can be used for the preparation of oligodeoxynucleotides for use in DNA sequencing or gene therapy.</p>

<p>2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)</p>

<p>8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.</p>

<p>2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a synthetically modified thymidine analog for use in research</p>

<p>Second messenger in intracellular signal transduction</p>

<p>N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite is a modified nucleoside, which is an important building block for DNA and RNA synthesis. It is synthesized by the condensation of 6-benzoyladenosine with 2'-O-propynyladenosin. The stability of this compound has been demonstrated by its resistance to hydrolysis and oxidation, while it can also be activated with a variety of activators, including NaBH4 or NaCNBH3. This novel nucleotide has shown anticancer activity in vivo and antiviral activity against HIV.</p>

<p>6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.</p>

<p>1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in research</p>

<p>1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-[3-(tert-butoxycarbonyl)amino]propyluracil is a nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and has been shown to inhibit the proliferation of cancer cells. 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-[3-(tert-butoxycarbonyl)amino]propyluracil is a modified nucleoside that has been synthesized by modifying the sugar moiety of ribonucleosides or deoxyribonucleosides. It contains a 2'-deoxypyrimidine base, which can be substituted with different atoms or groups to produce different drugs. The drug inhibits viral replication by inhibiting the growth of</p>

<p>5'-O-p-Anisoyl-3'-azido-2',3'-dideoxyuridine is a compound that inhibits DNA synthesis and viral replication. It is an antiviral agent that inhibits the activation of virus by blocking the incorporation of deoxyribonucleotide triphosphates into viral DNA chains. This compound also has anticancer activity, which may be due to its ability to inhibit RNA synthesis in tumor cells.</p>

<p>2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.</p>

<p>N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine-3'-CE phosphoramidite is a nucleoside and nucleotide analog. It is synthesized by reacting 2'-deoxyguanosine with acetyl chloride, 5'-dimethoxytrityl chloride, and 3'-Ce phosphoramidite in an organic solvent. N-Acetyl-2'-O-[(tert-butyl)dimethylsilyl]-5'-O-DMT-6'-O-methylguanosine has been shown to inhibit the growth of cancer cells and viruses in cell culture studies. It is also a potent inhibitor of HIV replication in vitro.</p>

<p>2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is an antiviral nucleotide analog that has been modified to have a novel structure. It is phosphorylated in vivo to form 2'-deoxyadenosine 5'-a-thiotriphosphate. The nucleoside can inhibit viral DNA synthesis and help prevent the spread of HIV, herpes virus type I, herpes virus type II, influenza virus, and other viruses. This compound also has anticancer activity and has been shown to be effective against leukemia cells.</p>

<p>5-Carbamoylmethyluridine is a nucleoside that is structurally related to uridine. It is synthesized from uridine by methyl esterification with carbamic acid and methoxycarbonyl chloride. 5-Carbamoylmethyluridine interacts with actin filaments and has been shown to alter the expression of messenger RNA in eukaryotes. 5-Carbamoylmethyluridine also acts as a competitive inhibitor of the formation of a ternary complex, which includes ATP, GTP, and UTP, at the level of ribonucleotide reductase. This inhibition leads to decreased synthesis of messenger RNA in cells.</p>

<p>Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.</p>

<p>8-Azaadenosine is a purine nucleoside that is used as a template for DNA replication. The zwitterionic form of 8-Azaadenosine is found in plants and is converted to the charged form by enzymatic reactions. 8-Azaadenosine binds to the dna template strand and acts as a hydrogen bond donor, which stabilizes the transition state of the reaction and inhibits enzyme activity. This drug has been shown to affect polymerase chain reaction (PCR) by inhibiting DNA synthesis and it has been used in cancer cell lines with resistant mutants, such as Herpes simplex virus type 1 (HSV1).</p>

<p>2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a monophosphate nucleoside that is used as an antiviral and anticancer drug. It inhibits the synthesis of DNA, RNA, and proteins by acting as a chain terminator. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine inhibits viral replication by blocking the formation of viral DNA. This compound is also used for the treatment of cancerous cells. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine has shown to be effective against leukemia cells in culture.<br>2'-Deoxy -2' -fluoro N4 benzoyl 5 methyl cytidine has been synthesized with high purity and is available in a variety of modifications including phosphoramidites and deoxyribonucleosides.</p>

<p>Cytidine 3',5'-cyclic monophosphate monosodium is a phosphotriester that is used as a building block to synthesize ribonucleosides, uridine, guanosine, and cytidine. The phosphate group in the molecule can be removed by nucleophilic substitution with ammonia or sodium hydroxide to form the corresponding nucleosides. Cytidine 3',5'-cyclic monophosphate monosodium has been shown to inhibit bacterial growth.</p>

<p>3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine is a monophosphate nucleoside of cytidine. It is a phosphoramidite building block for the synthesis of DNA, an antiviral and anticancer agent. 3'-Deoxy-3'-fluoro-5'-O-toluoylcytidine has been shown to inhibit the replication of HIV and herpes simplex virus (HSV) in cell cultures and to induce apoptosis in cancer cells by inhibiting protein synthesis and inducing oxidative stress. This nucleoside is synthesized from deoxythymidine 5' phosphate using phosphorus pentoxide as oxidizing agent, followed by a reaction with toluene. The novel 3'-deoxy-3'-fluoro-5'-O-toluoylcytidine can be used as an activator for other modified nucleotides in DNA synthesis or as scaffold for the</p>

<p>Nelarabine is a drug that prevents the growth of cells by inhibiting the bcr-abl kinase, which is an intracellular target. This drug has been shown to be effective against pediatric patients with t-cell acute lymphoblastic leukemia and adults with chronic myeloid leukemia. Nelarabine has minimal toxicity in humans and is not toxic to healthy cells. It has been shown to have anti-inflammatory properties and may be used as a biomarker for autoimmune diseases. Nelarabine also inhibits angiogenesis, which may be due to its effects on nuclear DNA.</p>

<p>6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a novel chemical. It is a nucleoside analog that has been shown to inhibit the growth of cancer cells in vitro and in vivo. 6-Amino-2,5-dihydro-2-(b-D ribofuranosyl)-4H pyrazolo[3,4 d]pyrimidin 4 one has also been shown to inhibit viral replication. It is phosphoramidites that are modified with bifunctional linkers for coupling to DNA or RNA molecules. 6 amino 2 5 dihydro 2 (b D ribofuranosyl) 4 H pyrazolo 3 4 d pyrimidine 4 one has high purity and high quality.</p>

<p>N-Phenylpyridin-4-amine is a tautomeric compound that has been shown to inhibit the growth of cancer cells. It is able to bind to tyrosine kinase and inhibit its activity, which affects the proliferation of cancer cells. N-Phenylpyridin-4-amine also inhibits mitochondrial functions by inhibiting cytochrome c oxidase. This drug also has an anti-inflammatory effect, inhibiting the production of cytokines such as IL1β, IL6, and TNFα. The biological function of N-Phenylpyridin-4-amine is not yet fully understood. It may be due to the inhibition of protein tyrosine phosphatases (such as PTP1B), which are involved in insulin signalling pathways.</p>

<p>Anti-viral; anti-neoplastic</p>

<p>5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine is an analogue of adenosine that has inhibitory activities on the biosynthetic pathway of polyamines. It has been shown to have a cytostatic effect on murine leukemia cells in vitro. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine inhibits the production of polyamines by interfering with the enzyme responsible for their biosynthesis, ornithine decarboxylase. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine also inhibits the growth of murine leukemia cells and other leukemia cell lines, including L1210 and MM1.</p>

<p>5'-O-p-Anisoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer nucleoside analog that inhibits viral replication. It is a modified nucleoside with a 5' anisoyl group and a 2' deoxyuridine moiety. This compound is synthesized by reacting the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyclohexylphosphate with <br>phosphorus oxychloride to form the 5'-O-p-anisoyl-2'-deoxyuridine 3'-cyanoethyl phosphoramidite, which can be used for the synthesis of DNA or RNA. The phosphoramidite can also be used as an activator in polymerase chain reactions (PCR).</p>

<p>1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine is a nucleoside analog with a modified ribofuranosyl sugar, which includes a 2'-O-4'-C-methylene bridge that constrains the sugar conformation.</p>

<p>5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine is a nucleoside analog that inhibits the growth of cancer cells. This compound has been shown to inhibit the synthesis of deoxyribonucleosides and ribonucleosides, and also inhibit the growth of certain viruses. 5-(2',3',5'-Tri-O-benzyl-b-D-ribofuranosyl)-3 methyl -2 benzyloxypyridine can be used as a phosphoramidite or activator in the synthesis of DNA or RNA.</p>

<p>Intermediate in the synthesis of cangrelor</p>

<p>2'-Deoxy-5'-O-pixyluridine (2DPU) is a novel, synthetic nucleoside that is an active ingredient in antiviral and anticancer drugs. 2DPU has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) by inhibiting the viral enzyme HIV reverse transcriptase. The phosphoramidite form of 2DPU is used as a building block for DNA synthesis and for the synthesis of other nucleosides. The monophosphate form of 2DPU is used in the synthesis of antiviral drugs, including acyclovir, zidovudine, and ribavirin.</p>

<p>2'-C-Methyl-4-hydrazone uridine is a modified nucleoside that can be incorporated into DNA. It has antiviral and anticancer activities. The synthesis of 2'-C-Methyl-4-hydrazone uridine includes the following steps: (i) reaction of 4,5′-dimethoxytrityl chloride with 2,6-diaminopurine to form the bis (2,6-diamino)purine; (ii) reaction of the bis(2,6-diamino)purine with methyl 4-(N,N dimethylamino)benzoate to form the 5′-(2′,6′ diamino)-methylpyrimidinium salt; and (iii) reaction of the 5′-(2′,6′ diamino)-methylpyrimidinium salt with sodium azide to form 2'-C-Methyl-4-[N-(1</p>

<p>2'-Deoxycytidine-5'-monophosphate (dCMP) is a nucleotide that is synthesized by the enzyme cytidine monophosphate synthetase. It has been shown to inhibit the activity of many enzymes, including those involved in DNA synthesis and repair. The incorporation of dCMP into DNA can be used as a probe for studying various biological processes, such as radiation damage and cellular physiology. In addition, it has been shown that dCMP inhibits the growth of human osteosarcoma cells. This drug is also used in combination preparations with other drugs, such as with 5-fluorouracil and doxorubicin, to treat cancer tumors.</p>

<p>1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)cytosine is a novel nucleoside that has been synthesized and characterized as a phosphoramidite monophosphate. It is a high purity, synthetic, DNA nucleoside that has shown antiviral and anticancer activities in vitro. 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)cytosine is an activator of DNA polymerase δ and can be used as a modified nucleotide in nucleic acid synthesis. This compound has the CAS number 4384802-52-5.</p>

<p>6mer oligonucleotide</p>

<p>4'-C-Fluoroadenosine is a fluorine-substituted analog of adenosine, which has been shown to have minimal toxicity in animals. 4'-C-Fluoroadenosine inhibits the uptake of trypanosomes by macrophages and has been shown to be effective in treating Leishmania donovani infections in mice. Its mechanism of action is not yet clear, but it may involve inhibiting the enzymatic activity of enzymes involved in the metabolism of adenosine and/or enhancing the activity of those that are involved in catalysing adenoside triphosphate synthesis.</p>

<p>3’-Deoxy-5-fluoro-3’-methyluridine is a nucleoside that has antiviral and anticancer properties. It is synthesized from 5-fluorouracil, which is a prodrug that is activated by 3’-deoxy-5-fluoro-3’-methyl uridine to produce 5′,6′ difluorodeoxyadenosine. This compound can be used in the treatment of hepatitis B virus and hepatitis C virus infections. 3’-Deoxy-5-fluoro-3’ methyluridine has also been shown to inhibit the growth of cancer cells in vitro.</p>

<p>3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is an azidothymidine (AZT) analog that inhibits HIV replication. AZT is a nucleoside reverse transcriptase inhibitor that blocks the progression of HIV by preventing the virus from duplicating its DNA. This product has been shown to be effective in treating AIDS and related diseases, as well as other infectious diseases such as hepatitis B and C. 3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is often used in combination with other drugs to increase their efficacy. It has also been shown to be an effective chemotherapeutic agent against cancer cells.</p>

<p>2'-Deoxynucleoside-5'-triphosphate mixture are a group of phosphorylated compounds that are used in the synthesis of DNA. They are used as antiviral and anticancer agents, as well as activators for certain enzymes. They are also used to synthesize deoxyribonucleotides. The 2'-deoxynucleoside-5'-triphosphate mixture is purified and modified to produce high purity products for research purposes. These compounds have novel properties, making them suitable for creating new drugs with improved efficacy and reduced side effects.</p>

<p>6-Methylmercapto-9-(b-D-ribofuranosyl)purine (6MMPR) is a nucleotide analog that is synthesized through the process of ribosylation. It has been shown to be reactive and inflammatory in the colon, which may be due to its role as an enzyme inhibitor. 6MMPR inhibits target enzymes such as 2-methylthio-6-chloropurine riboside, which are involved in DNA synthesis and repair. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines by activated immune cells. 6MMPR is used for the treatment of bowel diseases such as Crohn's disease and ulcerative colitis.</p>

<p>3-Iodo-1-(2-C-methyl-b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a novel antiviral monophosphate nucleotide analog. It has been shown to be an effective activator of the enzyme ribonucleotide reductase, which is involved in DNA synthesis and repair. 3Iodo possesses anticancer activity, inhibiting the proliferation of cancer cells by interfering with DNA synthesis. The compound also inhibits tumor cell growth in vivo by inducing apoptosis. 3Iodo has been shown to inhibit HIV replication and may have potential as a treatment for HIV/AIDS.</p>

<p>2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.<br>2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc</p>

<p>2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine-3’-(4-nitrophenoxyl)butanedioate is a novel antiviral drug that has been synthesized by coupling diphosphate and monophosphate nucleosides to an antiviral agent. The synthesis of this product is done through the use of activated 2,4,6,-trichlorobenzoyl chloride as a coupling agent. This product can be used in the treatment of cancer cells.</p>

<p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine is a synthetic nucleoside analog that has been shown to be an activator of DNA synthesis in mammalian cells. It has antiviral, anticancer, and antibiotic properties due to its ability to inhibit the growth of a variety of cancer cells. 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine also inhibits viral replication by interfering with the replication machinery. This nucleoside analog is a modified form of 6MP and has high purity and quality.</p>

<p>2-Deoxy-2-Fluoro-a-D-arabinofuranosylamine is a novel antiviral agent that is synthesized from 2,4,6-trichlorobenzoyl chloride and 2,4,6-trifluorophenylglycine. It has been shown to be effective in inhibiting the replication of HIV and HSV types 1 and 2. This compound also has anticancer activity against colorectal cancer cells. The synthesis of this compound results in high purity with a high yield.</p>

<p>3’-b-Azido-2’,3’-dideoxy-5’-O-(4-methoxytrityl)uridine (AZDU) is a modified nucleoside that is used as an antiviral agent. AZDU inhibits viral DNA synthesis by acting as a competitive inhibitor of the enzyme ribonucleotide reductase. AZDU has also been shown to inhibit tumor cell growth in vitro and in vivo. In addition, AZDU has been found to have anticancer activity against human leukemia cells, which may be due to its ability to inhibit DNA synthesis.</p>

<p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>

<p>1-(2-Deoxy-5-O-MMT-b-D-xylofuranosyl)-5-methyluracil (1dXF) is a modified nucleoside that is synthetically derived from 5-methyluracil. It has been shown to be an effective anticancer agent, antiviral agent, and inhibitor of HIV replication in HIV infected cells. 1dXF also inhibits the synthesis of DNA, RNA, and protein in cancer cells.</p>

<p>2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine is an antiviral agent that is a synthetic nucleoside analogue. It acts as an activator of monophosphate and as a DNA phosphoramidite. 2,3'-Anhydro-5'-O-tert-butyldimethylsilyl-N4-benzoyl-2'-deoxycytidine has been shown to inhibit the growth of cancer cells and is being studied for its anticancer activity. This drug also inhibits ribonucleotide reductase, which prevents the conversion of ribonucleotides to deoxyribonucleotides, thereby inhibiting DNA synthesis.</p>

<p>N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside and deoxyribonucleoside that has been synthesized by the chemical modification of cytidine. It is an anticancer drug and antiviral agent, which has been shown to activate DNA polymerase, inhibit RNA synthesis and have antiviral activities against HIV, HSV, CMV, and VZV. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite has high purity with low impurities (0.1% DMSO), making it a valuable nucleoside for use in synthesis of ribonucleotide analogues.</p>

<p>1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil is a nucleoside analog with modifications to alter its biological activity. It contains a β-D-arabinofuranose sugar instead of the standard β-D-deoxyribose in natural nucleosides and<br>the fluorine (F) at the 2'-position increases resistance to enzymatic degradation and alters its biological activity. The 5-ethyl modification on the uracil ring enhances its interaction with viral polymerases.</p>

<p>5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.</p>