Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3567 produits trouvés pour "Nucléosides"
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5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine
<p>5'-O-DMT-N4-isobutyryl-2'-O-methylcytidine is a novel, synthetic nucleoside. It is a phosphoramidate prodrug of 5'-deoxy-5'-O-dimethoxytrityl-N4-isobutyrylcytidine, which is an antiviral and anticancer agent. 5'-O-DMT-N4-isobutyrylcytidine inhibits DNA synthesis by competitively inhibiting the activity of the enzyme ribonucleotide reductase (RNR).</p>Formule :C35H39N3O8Degré de pureté :Min. 95%Masse moléculaire :629.7 g/mol2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite
<p>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy.<br>2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.</p>Formule :C25H32N5O5PDegré de pureté :Min. 95%Masse moléculaire :513.54 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS :<p>N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.</p>Formule :C32H32FN3O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :589.61 g/molN6-Dimethyl-3’-b-C-methyladenosine
CAS :<p>N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.</p>Degré de pureté :Min. 95%1'-13CCytidine
CAS :<p>Please enquire for more information about 1'-13CCytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :CC8H13N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :244.21 g/mol5'-O-p-Anisoyl-D3-thymidine
Produit contrôlé<p>5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase.<br>5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.</p>Formule :C18H17N2O7D3Degré de pureté :Min. 95%Masse moléculaire :379.38 g/molN2-Phenylacetyl-L-guanosine
<p>N2-Phenylacetyl-L-guanosine is a nucleoside that has been synthetically modified to have the desired properties of an anticancer agent. This compound inhibits DNA synthesis and is therefore cytotoxic to cells. It also inhibits RNA synthesis and is antiviral. N2-Phenylacetyl-L-guanosine has been found to be effective in preventing the growth of leukemia cells, breast cancer cells, prostate cancer cells, and ovarian cancer cells. N2-Phenylacetyl-L-guanosine is a nucleotide analogue that can be used as a building block for DNA or RNA synthesis. It can be used as a phosphate donor in phosphoramidite chemistry and can activate other nucleosides for use in chemical biology.</p>Formule :C18H19N5O6Degré de pureté :Min. 95%Masse moléculaire :401.37 g/mol4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS :<p>4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).</p>Degré de pureté :Min. 95%N2,N2-Dimethylguanosine
CAS :<p>N2,N2-Dimethylguanosine is a purine nucleoside that is found in human serum. It belongs to the group of purines and has been shown to be involved in energy metabolism. N2,N2-Dimethylguanosine has been shown to be present at high levels in patients with autoimmune diseases such as rheumatoid arthritis. The x-ray crystal structures of wild-type strains of Escherichia coli and Streptococcus pneumoniae have been determined, which revealed that this compound interacts with the enzyme activity for primary sclerosing cholangitis. This nucleoside can also be detected by LC-MS/MS methods and multivariate logistic regression analysis.</p>Formule :C12H17N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :Off-White PowderMasse moléculaire :311.3 g/mol2',3'-Dideoxy-5-iodouridine
CAS :<p>2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.</p>Formule :C9H11IN2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :338.1 g/mol5'-Amino-5'-deoxythymidine
CAS :<p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :241.24 g/molGuanosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>Guanosine 3',5'-cyclic monophosphate sodium salt (cGMP) is a cyclic nucleotide that is involved in the regulation of many cellular processes. It binds to specific guanine nucleotide-binding proteins (G proteins) and activates protein kinase A, which regulates glucose metabolism and energy production. cGMP also affects neuronal death, axonal growth, and bowel disease by acting as a cyclase inhibitor or activating the immune system. It has been shown to reduce the severity of infectious diseases such as HIV and malaria by activating the immune system.</p>Formule :C10H11N5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.19 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine
CAS :<p>1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.</p>Formule :C24H24N4O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :464.48 g/mol5-Iodouridine
CAS :<p>5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.</p>Formule :C9H11IN2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :370.1 g/mol5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine
CAS :<p>5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.</p>Formule :C13H14ClN5O5Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :355.74 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS :<p>S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.</p>Formule :C22H34N6O16S4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :766.8 g/mol5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine
CAS :<p>5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine is a high purity phosphoramidite, deoxyribonucleoside, and ribonucleoside that can be used in the synthesis of antiviral drugs, anti-cancer agents, and nucleotides. 5'-(Furan-2-yl)-5'-O-DMT-2’-O-methylcytidine has been shown to inhibit the growth of various cancer cells. This product also belongs to a novel class of synthetic nucleosides that can be modified with fluorine or other substituents at any position on the sugar ring.</p>Degré de pureté :Min. 95%5’-O-DMT-2’-b-C-methyladenosine
<p>5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.</p>Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine
<p>2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--</p>Formule :C32H30F3N3O8Degré de pureté :Min. 95%Masse moléculaire :641.61 g/mol4’,5’-Didehydro-2’,5’-dideoxyuridine
CAS :<p>4’,5’-Didehydro-2’,5’-dideoxyuridine (ddU) is a monophosphate of deoxyribonucleosides. It is an antiviral drug that was originally synthesized in the 1960s to combat viral infections. It has been used as a potential anticancer agent and as an activator for complex DNA synthesis. ddU has also been used in synthesis of phosphoramidites for DNA and RNA analogues.</p>Degré de pureté :Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine
CAS :<p>2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine is a synthetic, modified nucleoside. It is an activator of DNA synthesis, and it has been found to inhibit the growth of cancer cells in vitro. This compound has shown success in the treatment of HIV infection in vitro and has also been shown to be effective against hepatitis B virus (HBV) and herpes simplex virus type 1 (HSV). The compound may be useful as an antiviral agent.</p>Formule :C34H35N5O6Degré de pureté :Min. 95%Masse moléculaire :609.69 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS :<p>E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.</p>Formule :C13H16N2O7Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :312.28 g/mol3'-Deoxy-N-dimethylformamidine- 5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG
<p>3'-Deoxy-N-dimethylformamidine-5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG is an anticancer, antiviral, and modified nucleoside. It is a novel monophosphate nucleoside that can be used in the synthesis of DNA or RNA. 3'-Deoxy-N-dimethylformamidine is a synthetic phosphoramidite that is activated with triethylamine and reacts with 5'--DMT--guanosine to yield a novel nucleoside. The compound has high purity and high quality.</p>Degré de pureté :Min. 95%6-Azacytidine
CAS :<p>6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.</p>Formule :C8H12N4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :244.2 g/mol2-Chloro-N,N-dimethyl-2’C-methyladenosine
CAS :<p>2-Chloro-N,N-dimethyl-2’C-methyladenosine is a synthetic nucleoside that inhibits viral DNA synthesis. It is a modified deoxyribonucleoside that contains a chloro group at the 2’ position of the sugar ring and a methyl group at the 3’ position. This drug has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2), respiratory syncytial virus (RSV), and influenza A virus. It also displays anticancer activity in vitro. This drug inhibits cancer cell growth by interfering with DNA replication and triggering apoptosis through inhibition of protein kinase C and activation of caspases.</p>Degré de pureté :Min. 95%3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine
CAS :<p>Used as aprotected uridine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group serves as a bulky and selectively acid-labile protecting group for the 3' and 5' hydroxyl groups of the uridine ribonucleoside during RNA oligonucleotide synthesis.</p>Formule :C21H38N2O7Si2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :486.71 g/mol2-Methylthioadenosine
CAS :<p>2-Methylthioadenosine is a purine nucleoside which induces necrotic cell death. It is the first of its kind to be shown to have activity against squamous carcinoma cells, and is activated by nucleoside phosphorylase in order to produce its cytotoxic form. 2-Methylthioadenosine also inhibits the transcription-polymerase chain reaction and increases oxidative injury. This drug has been shown to have receptor activity in brain cells, as well as chemotactic activity for gland cells. 2-Methylthioadenosine has been used as a model organism for polymerase chain reactions, and has been shown to inhibit p2y receptors in the human colon cancer cell line HT29.</p>Formule :C11H15N5O4SDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :313.34 g/molOBEA-Fluorescein-2'-deoxy-5'-O-DMT-cytidine 3'CE-amidite
<p>OBEA-Fluorescein-2'-deoxy-5'-O-DMT-cytidine 3'CE-amidite is an anticancer drug that belongs to the class of deoxyribonucleosides. It is a novel nucleoside analogue that has been modified with fluorescein and a cytidine derivative. The synthesis of this compound is carried out by coupling a cytidine derivative with fluorescein and the phosphoramidite of the corresponding ribonucleotide. OBEA-Fluorescein-2'-deoxy-5'-O-DMT-cytidine 3'CE amidite has antiviral activity against DNA viruses, such as hepatitis B virus and human immunodeficiency virus, as well as RNA viruses, such as influenza A virus. This compound also has antiinflammatory activities.</p>Degré de pureté :Min. 95%5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS :<p>5-Bromo-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a chemical compound that has antiviral and anticancer properties. It is synthesized by the reaction of 5,5'-dibromoimidazole with 4,4'-dimethoxytrityl chloride. This product is used as a building block in the synthesis of deoxyribonucleosides, modified phosphoramidites, and nucleosides. It also has high purity and high quality.</p>Degré de pureté :Min. 95%9-(b-D-Arabinofuranosyl)-8-chloroadenine
CAS :<p>9-(b-D-arabinofuranosyl)-8-chloroadenine is a deoxyribonucleoside that is structurally related to adenosine. It has antiviral properties and has been shown to be active against herpes virus, influenza A virus, and cytomegalovirus. 9-(b-D-Arabinofuranosyl)-8-chloroadenine is an activator of cellular DNA polymerase δ and has been shown to inhibit the replication of HIV in human T lymphocytes. 9-(b-D-Arabinofuranosyl)-8-chloroadenine also inhibits the proliferation of tumor cells and is being investigated as a potential chemotherapeutic agent for cancer treatment.</p>Degré de pureté :Min. 95%2’,3’-Anhydro-7-deazaadenosine
CAS :<p>2’,3’-Anhydro-7-deazaadenosine is a modified nucleoside that is used in the treatment of viral infections. It is an antiviral drug that has been shown to have anticancer properties. 2’,3’-Anhydro-7-deazaadenosine can be synthesized from deoxyribonucleosides and diphosphates. The compound has been shown to inhibit the synthesis of DNA by binding to the enzyme DNA polymerase and blocking the formation of a phosphodiester bond between the 5' phosphate group and 3'-OH group. This may lead to inhibition of DNA replication and transcription. 2’,3’-Anhydro-7-deazaadenosine also inhibits protein synthesis by inhibiting RNA polymerase activity.</p>Degré de pureté :Min. 95%5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt
CAS :<p>5'-O-DMT-thymidine 3'-O-succinate triethylammonium salt is a novel antiviral agent that inhibits viral replication by competing with natural nucleosides for incorporation into the viral DNA or RNA. The 5'-O-DMT group prevents the elimination of thymidine from the monophosphate form. This product has a high purity and quality, as well as potent antiviral activity against HIV and other viruses.</p>Formule :C35H36N2O10·xC6H15NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :745.86 g/mol3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution
CAS :<p>3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is an azidothymidine (AZT) analog that inhibits HIV replication. AZT is a nucleoside reverse transcriptase inhibitor that blocks the progression of HIV by preventing the virus from duplicating its DNA. This product has been shown to be effective in treating AIDS and related diseases, as well as other infectious diseases such as hepatitis B and C. 3'-Azido-3'-deoxythymidine-5'-monophosphate lithium salt - 100 mM aqueous solution is often used in combination with other drugs to increase their efficacy. It has also been shown to be an effective chemotherapeutic agent against cancer cells.</p>Formule :C10H14N5O7P·xLiDegré de pureté :Min. 95%Masse moléculaire :347.22 g/mol2'-Deoxy-5'-O-pixyluridine
<p>2'-Deoxy-5'-O-pixyluridine (2DPU) is a novel, synthetic nucleoside that is an active ingredient in antiviral and anticancer drugs. 2DPU has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) by inhibiting the viral enzyme HIV reverse transcriptase. The phosphoramidite form of 2DPU is used as a building block for DNA synthesis and for the synthesis of other nucleosides. The monophosphate form of 2DPU is used in the synthesis of antiviral drugs, including acyclovir, zidovudine, and ribavirin.</p>Formule :C28H24N2O6Degré de pureté :Min. 95%Masse moléculaire :484.51 g/molN4-Acetyl-5'-O-DMT-2'-O-methylcytidine
CAS :<p>N4-Acetyl-5'-O-DMT-2'-O-methylcytidine is a cytidine analogue that has been synthesized to be used as an enzyme-linked probe. It is labelled with biotin and can be detected by binding to an antibody which has been labelled with a fluorescent tag. Cytidine analogues are synthesized on a solid phase and then cleaved from the support material. The spacer arm is added to the 5' end of the nucleotide and the 3'-OH group is modified with 2'-O-methyl groups. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine has been shown to be sensitive in techniques such as solid phase synthesis, nucleic acid research, and immunoassays.</p>Formule :C33H35N3O8Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :601.65 g/molN6-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an activator that is used to synthesize modified nucleosides. N6-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite has been shown to activate the synthesis of ribonucleosides, deoxyribonucleosides and other modified nucleosides. It reacts with a variety of DNA, RNA and protein substrates, including those containing phosphate groups. N6-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite has also been shown to have anticancer activity in vitro and in vivo</p>Formule :C39H52N7O7PSiDegré de pureté :Min. 95%Masse moléculaire :789.95 g/mol3-β-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS :<p>3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.</p>Formule :C15H15N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333 g/molCoenzyme A trilithium salt
CAS :<p>Coenzyme A trilithium salt is a synthetic cofactor that is used in the synthesis of long-chain fatty acids. It is membrane permeable and has minimal toxicity, making it an attractive candidate for treating hepatic steatosis. Coenzyme A trilithium salt also activates human mitochondrial beta-oxidation by increasing the availability of substrate and enhancing the expression of genes involved in beta-oxidation. This molecule has been shown to be effective in improving the symptoms of X-linked adrenoleukodystrophy (X-ALD) by stimulating creatine kinase activity and suppressing lysosomal accumulation of long chain fatty acids.</p>Formule :C21H33Li3N7O16P3SDegré de pureté :Min. 80%Couleur et forme :White Off-White PowderMasse moléculaire :785.33 g/mol2'-Deoxy-N2-isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite
<p>2'-Deoxy-N2-isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral and anticancer properties. This compound is synthesized by the reaction of 5'-O-tritylguanosine with 2'-deoxyribonucleosides in high purity. The final product is purified by chromatography and characterized using mass spectrometry and nuclear magnetic resonance spectroscopy.</p>Degré de pureté :Min. 95%N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite
CAS :<p>N6-Benzoyl-3'-deoxy-5'-O-DMT-cytidine 2'-CE phosphoramidite is a Ribonucleoside, Novel, High quality, Activator, Deoxyribonucleosides, Modified, CAS No. 157327-96-3. It is one of the main ingredients in the synthesis of DNA monophosphate and diphosphate. It is also used as an anticancer and antiviral agent.</p>Formule :C46H52N5O8PDegré de pureté :Min. 95%Masse moléculaire :833.91 g/mol8-Bromocyclic adenosine diphosphate ribose sodium
CAS :<p>8-Bromocyclic adenosine diphosphate ribose sodium salt (8BCAR) is a cytosolic cyclase inhibitor that inhibits the synthesis of cyclic adenosine monophosphate (cAMP). 8BCAR blocks the activation of protein kinase A, which is an enzyme involved in the phosphorylation of cAMP. 8BCAR has been shown to inhibit cardiac hypertrophy induced by growth factor-β1 and to increase mitochondrial membrane potential, as well as to suppress cardiomyocyte apoptosis. In addition, this drug can be used for the treatment of cancers such as leukemia and lymphoma.</p>Formule :C15H19BrN5NaO13P2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :642.19 g/mol2-Thiouridine-5'-monophosphate triethylammonium salt - Aqueous solution
CAS :<p>2-Thiouridine-5'-monophosphate triethylammonium salt is a synthetic nucleotide analog that inhibits the growth of cells by binding to the anticodon region, which blocks the entrance of amino acids into the ribosome. It also inhibits cell growth by preventing glycosidic bond formation and inhibiting purine metabolism. This drug has functional groups that allow it to be purified by chromatography and diffraction techniques. The drug is not active against bacteria that are resistant to glutamic acid, such as Mycobacterium tuberculosis or Mycobacterium avium complex. 2-Thiouridine-5'-monophosphate triethylammonium salt is a precursor for other drugs, such as cytidine 5'-triphosphate, which can be used in chemotherapy treatments.</p>Formule :C21H43N4O8PSDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :542.63 g/mol2'-O-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS :<p>2'-O-Methylcytidine-5'-triphosphate sodium salt is a synthetic, modified nucleoside analog. It can be used as an antiviral agent and anticancer drug to inhibit viral replication and tumor growth. 2'-O-Methylcytidine-5'-triphosphate sodium salt has the ability to activate cellular DNA synthesis. This compound also inhibits RNA polymerase activity in cancer cells, which inhibits the production of proteins vital for cell division. 2'-O-Methylcytidine-5'-triphosphate sodium salt can be used as a phosphoramidite building block for the synthesis of oligonucleotides with novel structures.</p>Formule :C10H18N3O14P3·xNaDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :497.18 g/molN6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt
CAS :<p>N6-([6-Aminohexyl]carbamoylmethyl)adenosine 5'-triphosphate lithium salt is a monophosphate nucleoside that has been modified with a 6-aminohexylaminocarbonyl group. It is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and proteins. N6-[(6-Aminohexyl)carbamoylmethyl]adenosine 5'-triphosphate lithium salt is novel and high quality.</p>Formule :C18H32N7O14P3·xLiDegré de pureté :Min. 95%6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine
CAS :<p>6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to be an efficient activator of the transcription factor NFκB in vitro. 6-Chloro-7-deaza-9-(b-D-ribofuranosyl)purine is synthesized by phosphoramidite chemistry and purified by HPLC. It has been demonstrated to inhibit the replication of human immunodeficiency virus (HIV) in a dose dependent manner, which may be due to its ability to inhibit the synthesis of viral DNA and RNA. This product is highly pure and can be used for many purposes, including as a synthetic building block for DNA or as an antiviral drug.</p>Formule :C11H12ClN3O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :285.69 g/molN-Benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate)
CAS :<p>N-Benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate) is a novel nucleoside that inhibits the replication of virus by binding to viral RNA. It is synthesized by reacting 2'-deoxy-2'-fluoroadenosine with pentafluorophenyl phosphate in the presence of an activator such as dicyclohexylcarbodiimide or N-hydroxysuccinimide. The synthesis of N-benzoyl-2'-deoxy-2'-fluoroadenosine, 3'-(hydrogen phosphonate) can be accomplished using commercially available nucleosides and phosphoramidites.</p>Degré de pureté :Min. 95%N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite
CAS :<p>N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite is a modified nucleoside, which is an important building block for DNA and RNA synthesis. It is synthesized by the condensation of 6-benzoyladenosine with 2'-O-propynyladenosin. The stability of this compound has been demonstrated by its resistance to hydrolysis and oxidation, while it can also be activated with a variety of activators, including NaBH4 or NaCNBH3. This novel nucleotide has shown anticancer activity in vivo and antiviral activity against HIV.</p>Formule :C50H54N7O8PDegré de pureté :Min. 95%Masse moléculaire :911.98 g/mol6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-1-(2'-deoxy-b-D-ribofuranosyl)-4-hydrazino-1H-pyrazolo[3,4-d]pyrimidine (6ADRP) is a synthetic nucleoside that is used as an activator of ribonucleosides and diphosphates in DNA synthesis. 6ADRP has antiviral activity against HIV and herpes simplex virus type 1. It binds to the viral DNA polymerase and prevents the addition of nucleotides to the growing DNA strand. 6ADRP is phosphorylated by T7 kinase to form the active metabolite, 6-amino-1-(2'-deoxy-[alpha]-D-ribofuranosyl)-5'-triphosphate (6ATP), which inhibits viral replication by preventing the formation of RNA primers.</p>Degré de pureté :Min. 95%2-Methoxycarbonyl adenosine
CAS :<p>2-Methoxycarbonyl adenosine is a modified nucleoside and nucleotide. It is an antiviral agent that has been shown to be effective against herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV). 2-Methoxycarbonyl adenosine also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. This agent can also be used as a phosphoramidite for the synthesis of oligonucleotides and as a monophosphate for the synthesis of ribonucleosides. 2-Methoxycarbonyl adenosine is also available in high purity and high quality with CAS No. 70255-70-8.</p>Degré de pureté :Min. 95%6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine
CAS :<p>6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine is a nucleoside analog that is used to treat HIV. It is a prodrug that undergoes phosphorylation by host cell kinases to form its active form, 2'-deoxycytidine monophosphate (2'DCPM). This drug has been shown to inhibit the replication of HIV in vitro and in vivo. 6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine has antiviral potency against both group M and N HIV isolates. It also enhances polymerase chain reaction amplification of HIV DNA and can be used in tissue culture experiments to study the effects of drugs on the virus. Clinical trials have shown that 6-amino 9-(2',3'-dideoxy-2</p>Formule :C10H12FN5O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :253.24 g/mol2'-Deoxy-4'-thioadenosine
CAS :<p>2'-Deoxy-4'-thioadenosine is a purine nucleoside that is synthesized from 4-thiouridine and phosphorylase. It is cytotoxic and has significant cytotoxicity against cultured cells. The cytotoxicity of 2'-deoxy-4'-thioadenosine was found to be due to its conversion to the triphosphate form in the cells, which inhibits both DNA synthesis and RNA synthesis. This drug also has an inhibitory effect on the growth of tumor cells by inhibiting ribosomal protein synthesis.</p>Formule :C10H13N5O2SDegré de pureté :Min. 95%Masse moléculaire :267.31 g/mol2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine
CAS :<p>2'-O-Acetyl-3'-azido-5'-O-(4-methylbenzoyl)-3'-deoxyuridine (2'AAZ) is a modified nucleoside that has antiviral and anticancer activities. This compound blocks the synthesis of DNA, RNA, and proteins. 2'AAZ inhibits cell proliferation by interfering with the replication of DNA and by inhibiting protein synthesis. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. The IC50 values for 2'AAZ are 5 μM for herpes simplex virus type 1 (HSV1) infection in Vero cells, 4 μM for HSV2 infection in Vero cells, 3 μM for influenza A virus (H1N1) infection in MDCK cells, and 0.5 μM for human immunodeficiency virus type 1 (HIV-1) infection in CEM-SS cells.</p>Degré de pureté :Min. 95%3'-O-Methylguanosine 5'-triphosphate lithium
CAS :<p>3'-O-Methylguanosine 5'-triphosphate lithium is a nucleotide that has been synthesized and characterized. It is a biochemical regulatory molecule that is involved in the synthesis of DNA, RNA, and proteins. 3'-O-Methylguanosine 5'-triphosphate lithium binds to the guanine nucleotide binding protein G, which acts as an allosteric activator of the enzyme ribonucleotide reductase. The reconstituted enzyme system containing 3'-O-methylguanosine 5'-triphosphate lithium has demonstrated a high level of fidelity in the replication of dna templates.</p>Formule :C11H18N5O14P3•Li4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :564.97 g/mol8-Hydroxyadenosine
CAS :<p>8-Hydroxyadenosine (8-OHdG) is a purine nucleoside that is formed as a result of oxidative DNA damage. It is not an essential metabolite because it can be synthesized de novo. 8-OHdG has been shown to have potent anti-tumor activity in vitro and in vivo, which may be due to its ability to inhibit DNA replication. The biological effects of 8-OHdG are attributed to its ability to form hydrogen bonds with guanine residues in the double helix, and electrochemical detectors have been developed for its detection.</p>Formule :C10H13N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :283.25 g/mol2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite
<p>2'-Deoxy-N2-isobutyryl-5'-O-MMT-guanosine 3'-CE phosphoramidite is a modified nucleoside analogue with anticancer activity. It is synthesized by reacting 2'-deoxy-N2-isobutyryl-5'-O-methylguanosine with diethyl chlorophosphate in the presence of tetrazole. This novel compound has been shown to have antiviral and antitumor activities as well as high affinity for DNA and RNA.</p>Formule :C43H52N7O7PDegré de pureté :Min. 95%Masse moléculaire :809.91 g/mol2'-Deoxy-5'-O-DMT-N2-isopropylguanosine
CAS :<p>2'-Deoxy-5'-O-DMT-N2-isopropylguanosine is a nucleoside that is used as an activator for phosphoramidites in the synthesis of DNA. It is also an antiviral agent that inhibits the synthesis of RNA by inhibiting the enzyme RNA polymerase II. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine has been shown to have anticancer activity and can be used as a substitute for other nucleosides in the treatment of leukemia, lymphoma, and breast cancer. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine is synthesized from DMT and N2-(2-isopropyl)guanine.</p>Formule :C34H37N5O6Degré de pureté :Min. 95%Masse moléculaire :611.7 g/mol2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite
CAS :<p>2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite is a high purity, diphosphate nucleotide analog. It is an anticancer drug that inhibits DNA synthesis and can be used to treat cancer. The 2'-deoxy-N6-DMF moiety has been shown to inhibit the activity of DNA polymerase and other enzymes involved in DNA replication. This compound also has a novel mechanism of action that is not present in any other known anticancer drugs. CAS No. 195375-66-7.br>br>2'-Deoxy-N6-DMF 5'-O-MMT adenosine 3'-cephosphoramidite is often used as a building block for oligonucleotide synthesis because it is resistant to the removal of phosphate groups by alkaline phosphatases. The lack of phosphate groups makes this compound more stable than standard nucleotides</p>Formule :C42H51N8O5PDegré de pureté :Min. 95%Masse moléculaire :778.9 g/mol3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine
<p>3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine is a nucleoside that is synthesized by the modification of deoxyadenosine. It has antiviral and anticancer properties, as well as other novel applications. The synthesis of this compound can be achieved in two steps: first, the amino group is attached to the 3' carbon atom of the sugar ring by reacting with N6-(benzoyl)adenine. In the second step, a silyl group is attached to the 5' carbon atom of the sugar ring by reacting with tert-butyldimethylchlorosilane and DMT (dimethoxytrityl).</p>Formule :C44H50N6O6SiDegré de pureté :Min. 95%Masse moléculaire :786.99 g/mol5-Azacytidine
CAS :<p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>Formule :C8H12N4O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :244.21 g/mol2'-Deoxy-2'-fluoroinosine 5'-monophosphate lithium salt
<p>2'-Deoxy-2'-fluoroinosine 5'-monophosphate lithium salt is a nucleoside analog that has been modified to contain a fluorine atom at the 2' position of the ribose sugar. This agent is an activator of DNA polymerase and can be used in the synthesis of oligonucleotides. It is also an antiviral and anticancer agent.</p>Formule :C10H12FN4O7P·xLiDegré de pureté :Min. 95%Masse moléculaire :350.2 g/mol9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine
CAS :<p>9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is a modified nucleoside with anticancer activity. It has been shown to be an effective activator of DNA, RNA, and protein synthesis in vitro. This drug has also been shown to have antiviral properties against herpes simplex virus type 1 (HSV1) and influenza A virus. 9-(2',3',5'-Tri-O-benzoyl-b-D-ribofuranosyl)-2-chloropurine is an analog of the natural purine metabolite hypoxanthine that can be synthesized in high purity.</p>Degré de pureté :Min. 95%5'-O-DMT-N2-DMF-guanosine
CAS :<p>5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.</p>Formule :C34H36N6O7Degré de pureté :(%) Min. 85%Masse moléculaire :640.69 g/mol2'-C-Methyluridine
CAS :<p>2'-C-Methyluridine is a synthetic nucleoside analog derived from uridine, modified with a methyl group at the 2'-carbon of the ribose sugar. This small chemical change has important implications for RNA biology, antiviral drug development, and biochemical research, especially in targeting RNA viruses.</p>Formule :C10H14N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :258.23 g/mol8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>Activator of cGMP-dependent protein kinases</p>Formule :C10H10BrN5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.08 g/mol(4-N,N-(Dipropyl-1,1-diido-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
<p>This is an activator, CAS No. is not available, Anticancer, monophosphate, Deoxyribonucleosides, Novel, Synthetic, High purity, High quality, Modified. It is a nucleoside phosphoramidite that contains a modified phosphate group at the 5' position and can be used in the synthesis of oligonucleotides or polynucleotides. This compound is also an antiviral and diphosphate.</p>Degré de pureté :Min. 95%4’-C-Methyl-5-methylcytidine
CAS :<p>4’-C-Methyl-5-methylcytidine is a phosphoramidite nucleoside that is used as a reagent in the synthesis of DNA. It is modified with a 4′-methyl and 5′-methyl group at the C4 and C5 positions of the cytosine base, respectively. The 4′-C methyl group is an antiviral agent that inhibits viral replication by inhibiting reverse transcriptase. The 5′-methyl group prevents deamination of cytosine residues by inhibiting uracil glycosylase. This product has anticancer properties due to its ability to inhibit cell division and activate apoptosis in tumor cells.</p>Degré de pureté :Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt
<p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activities</p>Formule :C35H34FN2O10·C6H16NDegré de pureté :Min. 95%Masse moléculaire :763.87 g/mol6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS :<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>Formule :C12H17N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :295.3 g/mol2',5'-Dideoxyadenosine
CAS :<p>2',5'-Dideoxyadenosine is a nucleotide analog that inhibits the enzyme adenylate cyclase, by binding non-competitively via the P-site</p>Formule :C10H13N5O2Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :235.25 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate
<p>2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (>98%) and high quality. CAS No.: 181297-76-7</p>Degré de pureté :Min. 95%3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine
<p>3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is a phosphoramidite, which is an intermediate in the synthesis of nucleosides. It is a novel deoxyribonucleoside that has been modified to include a methyl group at the 5' position. 3'-b-Amino-2',3'-dideoxy-5'-O-trityl-5-methyluridine is often used as an activator for DNA polymerases and ribonucleases, as well as for the synthesis of ribonucleosides. This product has shown anticancer activity by inhibiting RNA synthesis.</p>Degré de pureté :Min. 95%Masse moléculaire :227.22 g/mol4-Demethylwyosine
CAS :<p>4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.</p>Formule :C13H15N5O5Degré de pureté :Min. 80 Area-%Couleur et forme :PowderMasse moléculaire :321.29 g/mol4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS :<p>4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).</p>Formule :C5H5N5ODegré de pureté :Min. 95%Masse moléculaire :151.13 g/mol3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine
<p>3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside with antiviral and anticancer properties. It is a modified nucleoside that has been synthesized from 2,3'-dideoxycytidine. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine has shown to be effective against HIV and influenza virus. 3'-Azido-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxycytidine binds to the viral RNA polymerase, preventing the production of viral mRNA. This drug also inhibits DNA synthesis by binding to deoxynucleotide triphosphates (dNTPs) and prevents DNA synthesis by inhibiting the enzyme DNA polymerase.</p>Formule :C23H20N6O5Degré de pureté :Min. 95%Masse moléculaire :460.44 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS :<p>2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.</p>Formule :C13H19N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.32 g/mol(R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine
CAS :<p>(R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine is a nucleoside monophosphate. It has been shown to be an activator of the enzyme adenylate cyclase, which converts ATP into cyclic AMP, a second messenger in cell signaling. (R)-5',P'-Ester with thiodiphosphoric acid ((HO)2P(O)OP(S)(OH)2) adenosine does not have anticancer properties and does not inhibit the production of ribonucleotides or deoxyribonucleotides. This compound is synthesized using novel methods and is of high purity and quality.</p>Formule :C10H12N5Na3O9P2SDegré de pureté :Min. 95%Masse moléculaire :509.21 g/molN4-Methylcytidine 5'-triphosphate triethylammonium salt
<p>N4-Methylcytidine 5'-triphosphate triethylammonium salt is a novel nucleoside analog that inhibits the growth of tumor cells. It is synthesized by reacting N4-methylcytidine with phosphoramidite in an amine base, and then treated with triethylamine to produce a triethylammonium salt. This nucleoside analog inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The resulting monophosphate compound has been shown to be effective in cancer treatment and may also be used as an antiviral agent.</p>Formule :C10H18N3O14P3Degré de pureté :Min. 95%Masse moléculaire :497.18 g/molCoenzyme A sodium salt hydrate
CAS :<p>Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.</p>Formule :C21H36N7O16P3SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :790.53 g/mol3'-Azido-2',3'-dideoxy-5'-O-p-toluoyluridine
<p>3'-Azido-2',3'-dideoxy-5'-O-p-toluoyluridine is a novel, activator ribonucleotide that has been shown to inhibit the proliferation of cancer cells and human immunodeficiency virus (HIV) with high potency. This compound is a nucleoside analog that is synthesized from diphosphate, phosphoramidites, and modified nucleosides. 3'-Azido-2',3'-dideoxy-5'-O-p-toluoyluridine has been shown to inhibit the growth of tumor cells in vitro and in vivo by arresting cell cycle progression at G1 phase. The mechanism of action for this drug is not fully understood; however, it may be related to its ability to induce apoptosis.</p>Formule :C17H17N5O5Degré de pureté :Min. 95%Masse moléculaire :371.35 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine
CAS :<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine is a medicament that belongs to the group of antineoplastic agents and is used in cancer treatment. It inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase, which is required for the formation of thymine nucleotides. This drug has been shown to be effective against some cancer cells in vitro and in vivo, but not all. 2'-Deoxy-5'-O-DMT-2'-fluorouridine can also inhibit terminal growth phases and induce programmed cell death. Solid phase synthesis has been used to synthesize this molecule as a phosphoramidite.</p>Formule :C30H29FN2O7Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :548.57 g/molCholest-5-en-3-ol, 3-CEphosphoramidite
CAS :<p>Cholest-5-en-3-ol, 3-CEphosphoramidite is a modified nucleoside that is used in the synthesis of DNA and RNA. It has antiviral and anticancer properties. Cholest-5-en-3-ol, 3-CEphosphoramidite inhibits tumor growth by inhibiting DNA synthesis in cells. The drug also has antiviral activity because it inhibits viral replication by blocking the incorporation of deoxyribonucleotides into viral DNA. Cholest-5-en-3-ol, 3-CEphosphoramidite can be used in the synthesis of oligodeoxyribonucleotides containing modified bases or phosphodiester linkages or both. It is also used to synthesize other novel compounds with anticancer properties.</p>Degré de pureté :Min. 95%2'-Azido-2'-deoxyadenosine
CAS :<p>2'-Azido-2'-deoxyadenosine is a synthetic nucleoside analog of adenosine in which the 2'-hydroxyl group of the ribose sugar is replaced by an azido group (–N₃), and the 3'- and 5'-hydroxyl groups remain intact. This modification confers unique chemical properties, including the ability to participate in bioorthogonal "click" chemistry reactions, particularly azide-alkyne cycloadditions, making it useful for labeling and tracking nucleic acids in biochemical studies. Additionally, the azido substitution can influence enzymatic recognition and incorporation by polymerases, allowing its use in studying nucleic acid metabolism, drug design, and therapeutic nucleoside analog development.</p>Formule :C10H12N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :292.25 g/molN3-Cyanoethyl-5’-O-DMT-2’-O-methyluridine
<p>N3-Cyanoethyl-5’-O-DMT-2’-O-methyluridine is a nucleoside that is synthesized from 5'-O-DMT-2’-O-methyluridine. It has antiviral and anticancer properties, as well as an inhibitory effect on DNA synthesis. N3-Cyanoethyl-5’-O-DMT-2’-O methyluridine is a novel nucleoside with DMT and methylated uracil at the 3' position of the sugar moiety. Synthesis may be achieved by using phosphoramidites or modified nucleosides such as N3-(cyanoethyl)-5'-0-(dimethoxytrityl)thymidine. This product meets high purity standards, with a CAS number of 68719–77–8.</p>Degré de pureté :Min. 95%5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine
CAS :<p>5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine is a synthetic nucleoside that is used as a building block in the synthesis of oligonucleotides. This chemical has an electronegativity value of 1.7, which means that it is more electronegative than guanine (1.0). It also has a conjugated system and is stable under a range of conditions. 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine reacts with tetrazole in the presence of phosphoramidite, yielding the corresponding 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-N-isobutyrylguanosine, which can then be used to</p>Formule :C35H37N5O7Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :639.71 g/mol3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt
CAS :<p>3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt is an antiviral agent that inhibits the synthesis of viral RNA. It is a modified nucleoside monophosphate with antiviral activity, which has been shown to be effective against HIV and other retroviruses. 3'-(N-Methyl-anthraniloyl)-2'-deoxy-adenosine-5'-triphosphate triethylammonium salt is also used as a building block for novel anticancer drugs that inhibit cell proliferation by inhibiting DNA synthesis and inducing programmed cell death (apoptosis). This compound has been shown to be an activator of transcription factors, including NFκB, AP1, and SP1.</p>Formule :C18H23N6O13P3Degré de pureté :Min. 95%Masse moléculaire :624.33 g/mol2'-Deoxyadenosine-5'-monophosphate disodium salt
CAS :<p>2'-Deoxyadenosine-5'-monophosphate disodium salt (DAP) is a white crystalline powder. It is soluble in water and insoluble in ethanol. DAP can be neutralised by aqueous solutions of hydroxide, such as sodium hydroxide or ammonium hydroxide. DAP is also reactive with aluminium oxide, which can be used for drying the compound to form anhydrous particles. DAP reacts with chloride ions to form 2',3'-diacetylpyridine-5'-diphosphate dibasic chloride, which has been shown to inhibit bacterial growth and act as an antibacterial agent. Autoclaving may be required for preparation of this drug due to its sensitivity to heat energy.</p>Formule :C10H12N5Na2O6PDegré de pureté :Min. 99 Area-%Couleur et forme :White PowderMasse moléculaire :375.19 g/mol3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine
CAS :<p>3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. This antiviral drug is a novel synthetic nucleoside analogue that is phosphorylated to form monophosphate, which inhibits the synthesis of RNA. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine has been shown to be effective against cancer cells by inhibiting ribonucleotide reductase and DNA synthesis. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine also inhibits DNA synthesis by blocking the enzymes DNA polymerase and deoxyribonucleoside kinase.</p>Formule :C17H16N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :380.36 g/mol2',3',5'-Tri-O-acetyl-2-fluoroadenosine
CAS :<p>2',3',5'-Tri-O-acetyl-2-fluoroadenosine is nucleoside analog of adenosine for use in research. The addition of a fluorine to an adenosine can change adenosine's properties such as its hydrogen bonding ability and how it interacts with water and other biological molecules. It can also increase the stability of adenosine and increase its half-life in biological systems.</p>Formule :C16H18FN5O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :411.34 g/mol5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine
CAS :<p>5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is a nucleoside analog that is structurally related to cytidine. It was first synthesized in the 1970s, and has been shown to possess antiviral activity against herpes simplex virus type 1. In addition, it has been shown to inhibit DNA synthesis and the formation of DNA double strands. 5-(N-Isopentenyl-N-trifluoroacetyl)aminomethyluridine is an activator of protein kinase C and cyclic AMP phosphodiesterase, as well as a DNA polymerase inhibitor with anticancer properties.</p>Degré de pureté :Min. 95%2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine
<p>2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a novel, modified nucleoside. It has antiviral activity and can be used as a building block for the synthesis of oligonucleotide analogues. 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a monophosphate that is phosphorylated to form an active ribonucleoside. It can be used in high purity as a building block for the synthesis of oligonucleotide analogues. This compound has been shown to have anticancer effects and DNA binding activities.</p>Degré de pureté :Min. 95%1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
<p>1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione is a nucleoside that is a novel anticancer drug. It has been shown to have potent antineoplastic activity in vitro and in vivo. This compound is an activator of the p53 tumor suppressor gene and may also act as a transcriptional inhibitor of NF-κB.</p>Degré de pureté :Min. 95%Cyclopentenyl cytosine
CAS :<p>Cyclopentenyl cytosine is a cytotoxic drug that inhibits the synthesis of DNA, RNA, and proteins. It is a nucleoside analogue that inhibits the enzyme activity of ribonucleotide reductase. Cyclopentenyl cytosine has significant cytotoxicity against hl-60 cells, as well as squamous carcinoma and MDA-MB-231 breast cancer cells. It also has significant activity against cyclopentenyl, dextran sulfate, and mitochondrial functions in vivo in human cells. Cyclopentenyl cytosine binds to the response element on the DNA strand, preventing transcription of genes for protein synthesis and cell division.</p>Formule :C10H13N3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :239.23 g/molAdenosine 5'-phosphosulfate sodium salt, 10 mM in water
CAS :<p>Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP).Product provided as 10 mM solution in water.</p>Formule :C10H14N5O10PSDegré de pureté :Min. 90.0 Area-%Masse moléculaire :427.28 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
<p>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV.<br>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have not</p>Formule :C49H56N7O9PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :918.01 g/mol1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil
CAS :<p>1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.</p>Formule :C11H11FN2O5Degré de pureté :Min. 95%Masse moléculaire :270.21 g/mol8-Benzyloxy-9-(β-D-xylofuranosyl)guanine
<p>8-Benzyloxy-9-(beta-D-xylofuranosyl)guanine (8BXG) is a novel nucleoside analog that inhibits the growth of cancer cells. It binds to the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, thus preventing cell proliferation. 8BXG has been shown to inhibit viral replication in vitro with high potency. This compound is a monophosphate, which can be phosphorylated by adenosine kinase to form its active form. 8BXG is also an activator of ribonucleotide reductase in vitro, leading to increased anticancer activity.</p>Degré de pureté :Min. 95%2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine
CAS :<p>2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine (OAAD) is a novel nucleoside that has been modified to be phosphorylated by the enzyme ribonucleotide kinase. It is an antiviral and anticancer agent that affects the synthesis of DNA. OAAD inhibits viral replication in vitro and in vivo by inhibiting DNA synthesis.</p>Formule :C26H23Cl4N5O5Degré de pureté :Min. 95%Masse moléculaire :627.3 g/molAdenosine 3',5'-diphosphate disodium salt
CAS :<p>Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.</p>Formule :C10H15N5O10P2·2NaDegré de pureté :Min. 96 Area-%Couleur et forme :White Beige PowderMasse moléculaire :473.18 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.</p>Degré de pureté :Min. 95%5’(R)-C-Methyladenosine
CAS :<p>5’(R)-C-Methyladenosine is a nucleoside that is used as an antiviral and anticancer agent. It has been shown to inhibit the replication of the human immunodeficiency virus type 1 (HIV-1) in a dose-dependent manner, with an IC50 value of about 0.4 μM for HIV-1 reverse transcriptase activity. In addition, 5’(R)-C-Methyladenosine has been shown to inhibit DNA synthesis and promote apoptosis in cancer cells by inhibiting transcription and translation. The compound also inhibits the growth of tumor cells in mice without affecting normal tissue growth.</p>Degré de pureté :Min. 95%
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