Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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4-Chloro-6-imidazol-1-yl-pyrimidine
CAS :4-Chloro-6-imidazol-1-yl-pyrimidine is a quaternary ammonium compound that can be used to make antireflection coatings. It has been shown to have a high degree of compatibility with polymers, such as allyl carbonate, which are used in functional groups. 4-Chloro-6-imidazol-1-yl-pyrimidine has also been shown to react with stannous octoate, and the reaction time is dependent on the concentration of both compounds. This molecule has been found to be biodegradable and liquid crystal compositions can be made from it by changing the ratio of molecules to liquid crystals. 4-Chloro-6-imidazol-1-yl pyrimidine reacts with hydroxyl groups in epoxy resins and diolefinic hydrocarbons, forming crosslinks in sealants or coatings. The sealantFormule :C7H5ClN4Degré de pureté :Min. 95%Masse moléculaire :180.59 g/molLamivudine 5'-diphosphate ammonium salt
CAS :Lamivudine is a monophosphate antiviral drug that inhibits the synthesis of DNA. It has been shown to inhibit the replication of human immunodeficiency virus-1 (HIV-1) in vitro, and to protect monkeys from simian acquired immune deficiency syndrome (SAIDS). Lamivudine 5'-diphosphate ammonium salt is an antiviral agent that belongs to the group of deoxyribonucleosides. It has been shown to be effective against HIV-1 and SAIDS in animals. The mechanism of action is not fully understood, but it may work by inhibiting viral RNA synthesis or by preventing viral DNA integration into host cell DNA.
Formule :C8H19N5O9P2SDegré de pureté :Min. 95%Masse moléculaire :423.28 g/mol1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a novel modified nucleoside that is used as an activator in the synthesis of oligodeoxynucleotides and ribonucleosides. It is also used for the synthesis of phosphoramidites for DNA and RNA molecules. This product is available in high purity and quality.Formule :C18H19N5O4Degré de pureté :Min. 95%Masse moléculaire :369.38 g/mol2-Amino-4-(4-methoxyphenyl)pyrimidine
CAS :2-Amino-4-(4-methoxyphenyl)pyrimidine (AMP) is a synthetic nucleoside analog. It has antiviral activity and is used for the treatment of hepatitis B virus infection. AMP inhibits viral DNA polymerase and prevents the synthesis of viral DNA and RNA. It has been modified to include a methoxy group at the 4 position, which provides additional stability against the enzyme ribonuclease. AMP is also an activator of ribonucleotide reductase and can be used as a substrate to synthesize deoxyribonucleosides, phosphoramidites, diphosphate, or monophosphate nucleotides for DNA synthesis.
AMP has CAS number 99844-02-7 and is available in high purity.Formule :C11H11N3ODegré de pureté :Min. 95%Masse moléculaire :201.22 g/molN6-Benzoyl-7-deaza-2'-deoxyadenosine
CAS :N6-Benzoyl-7-deaza-2'-deoxyadenosine is a novel synthetic monophosphate activator that can be used to induce cell death in cancer cells. It is structurally similar to the natural nucleotide adenosine, and it binds to the same receptors on cells as adenosine. N6-Benzoyl-7-deaza-2'-deoxyadenosine has been shown to inhibit viral replication by interfering with DNA synthesis and RNA transcription, which are essential for viral reproduction.Formule :C18H18N4O4Degré de pureté :Min. 95%Masse moléculaire :354.36 g/mol2-Amino-2'-deoxyadenosine 5'-triphosphate
CAS :2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.Formule :C10H17N6O12P3Degré de pureté :Min. 95%Masse moléculaire :506.2 g/mol5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA)
5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is a nucleoside that belongs to the group of modified nucleosides. It is used as an activator for phosphoramidite synthesis and as an antiviral agent. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) has been shown to have anticancer activity by inhibiting DNA, RNA, and protein synthesis in tumor cells and also stimulating apoptosis. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is synthesized from uracil, which is obtained by the hydrolysis of thymine or cytosine. This product is available with a high quality at a competitive price.Degré de pureté :Min. 95%2’-O,4’-C-Methylenecytidine
CAS :2’-O,4’-C-Methylenecytidine is a nucleoside that has been used to synthesize oligonucleotides. It has been shown to form duplexes with complementary DNA and RNA strands. 2’-O,4’-C-Methylenecytidine forms bicyclic analogues with high efficiency and can be used as an n-type structural probe.Degré de pureté :Min. 95%2’-Deoxy-8-methylthioadenosine
CAS :2’-Deoxy-8-methylthioadenosine is a monophosphate and antiviral compound. It is used for the treatment of viral infections and has been shown to be active against herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus, and human immunodeficiency virus. The compound inhibits the activity of DNA polymerase by competing with deoxyribonucleosides as substrates. This results in the inhibition of DNA synthesis. 2’-Deoxy-8-methylthioadenosine also inhibits ribonucleotide reductase, which is an enzyme that catalyzes the production of ribonucleotides from deoxyribonucleotides. 2’-Deoxy-8-methylthioadenosine has been shown to inhibit cell proliferation in vitro and in vivo through G2/M phase arrest and apoptosis induction.Degré de pureté :Min. 95%3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine
CAS :3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is an anticancer drug that inhibits the growth of cells by preventing DNA synthesis. It is a modified nucleoside that is synthesized from thymidine and has been shown to have antiviral and anti-inflammatory properties. 3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is also used in the production of phosphoramidites and ribonucleotides.Formule :C30H40N4O4SiDegré de pureté :Min. 95%Masse moléculaire :548.7 g/molN5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å
N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å is a modified nucleoside that is used for the synthesis of DNA and RNA. It is an activator of antiviral and anticancer drugs. N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å has been shown to be an effective cancer treatment agent in vivo, as well as an inhibitor of viral replication. It can also be used in the synthesis of nucleosides and phosphoramidites.Degré de pureté :Min. 95%Couleur et forme :Powder3’-O-tert-Butyldiphenylsilylthymidine
CAS :Used as a protected thymidine nucleoside in chemical synthesis, specifically as an intermediate in the preparation of other thymidine derivatives, particularly 5'-modified nucleosides and oligonucleotides. The tert-butyldiphenylsilyl (TBDPS) group is a silyl protecting group selectively attached to the 3' hydroxyl group of thymidine.Formule :C26H32N2O5SiDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :480.63 g/molL-5-methyluridine
CAS :L-5-methyluridine is a nucleoside that is used as a building block in the synthesis of oligonucleotides. It contains one ribose sugar and one deoxyribose sugar, linked to the base adenine by a phosphate group. L-5-methyluridine can be synthesized from 5-chloro-2'-deoxyadenosine, hypoxanthine, and ammonium chloride. The synthesis starts with condensation reactions between the two sugar molecules to form an intermediate called a nucleoside. This is followed by alkylation of the base and then oxidation of the sugar group to form anomeric esters. The last step involves hydrolysis of the acyloxy ester, which yields L-5-methyluridine after acidification.Formule :C10H14N2ODegré de pureté :Min. 95%Masse moléculaire :178.23 g/mol2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite
2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral activity. It can be synthesized from 2'-deoxyribonucleosides and 5'-thioinosine monophosphate. This compound inhibits viral replication by inhibiting the synthesis of viral diphosphate, which is required for DNA synthesis. The compound also has anticancer properties and can inhibit the growth of tumor cells by blocking the process of DNA synthesis.Degré de pureté :Min. 95%2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS :2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt is a circularization agent that can be used in the efficient method for the synthesis of DNA. It inhibits the growth of bacteria by binding to their DNA and preventing transcription. 2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt has shown inhibitory effects against tuberculosis and other infectious diseases, including diphtheria, tetanus, typhoid fever, and malaria. This drug also prevents the replication of viral RNA. The inhibition occurs through an analog mechanism at the level of nucleic acid synthesis or polymerase chain reaction (PCR). The thiophosphate group is cleaved from the triphosphate moiety in the presence of metal ions such as Zn2+, Mg2+, Mn2+, or Ca2+. The active form is enzymatically hydrolyzed by covalent enzyme activity toFormule :C10H16N5O11P3S·xLiDegré de pureté :Min. 95%Masse moléculaire :507.25 g/molN-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine
CAS :N-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine is a synthetic nucleoside that is an activator of DNA polymerase and has antiviral activities. It is also used in the synthesis of deoxyribonucleosides, phosphoramidites, and ribonucleosides.Formule :C41H41N5O8Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :731.79 g/molAristeromycin
CAS :Carbocyclic nucleoside antibioticFormule :C11H15N5O3Degré de pureté :Min. 95%Masse moléculaire :265.27 g/mol2',3',5'-Tri-O-acetyl-5-methyluridine
2',3',5'-Tri-O-acetyl-5-methyluridine is a nucleoside that is used as a substrate for the enzyme, methylmagnesium (MeMg) nucleotides. It has been shown to have a high basicity and is a good substrate for the enzyme, MeMg nucleotides. 2',3',5'-Tri-O-acetyl-5-methyluridine also has stereoselectivity and can be synthesized with high purity.Degré de pureté :Min. 95%2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate
2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is a modified nucleotide analog that is used as an antiviral agent. It inhibits the synthesis of viral DNA by competitively inhibiting the incorporation of deoxyribonucleoside triphosphates into the growing DNA chain. 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is phosphorylated to 2-[2-(2,6,8,10,12,14,16,-doxohexadecyl)-1H--imidazo[4,5--c]pyridine--1--carboxylic acid]ethanol phosphate in vivo and this active form inhibits human immunodeficiency virus type 1 (HIV1) replication in vitro with an IC 50 of 0.06 μM.Formule :C10H15ClN5O13P3Degré de pureté :Min. 95%Masse moléculaire :541.63 g/mol1-(b-D-Xylofuranosyl)cytosine
CAS :1-(b-D-Xylofuranosyl)cytosine is a nucleoside analog that is used in the treatment of cancer. It inhibits DNA replication by binding to the RNA template strand and blocking the incorporation of cytosine. 1-(b-D-Xylofuranosyl)cytosine has been shown to have an inhibitory effect on tumor cell lines, with a thermal expansion coefficient similar to biphenyl. The molecular weight of 1-(b-D-xylofuranosyl)cytosine is approximately 244 g/mol, which is greater than that of water (18 g/mol). 1-(b-D-xylofuranosyl)cytosine also binds to double stranded DNA with high affinity, leading to inhibition of protein synthesis and cell division. In addition, this compound has been shown to bind to naphthalene and form adducts with its hydroxyl groups.Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :243.22 g/mol
