Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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Pyrimidine-5-carboxamidine hydrochloride
CAS :<p>Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.</p>Formule :C5H6N4·HClDegré de pureté :Min. 95%Masse moléculaire :158.59 g/mol2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine
CAS :<p>2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.</p>Degré de pureté :Min. 95%1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS :Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Formule :C29H53N3O4Si3Degré de pureté :Min. 95%Masse moléculaire :592.01 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used in the synthesis of DNA. It is an activator for antiviral and anticancer drugs, as well as a ribonucleoside monophosphate, diphosphate, or deoxyribonucleoside. N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite has been shown to have a novel anticancer activity.</p>Degré de pureté :Min. 95%5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine
<p>5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, also known as 5'-O-(4,4'-dimethoxytrityl)-N4-isobutyryl-2'-O-methyl-5-methylcytidine, is a nucleoside and nucleotide analog. It is an antiviral agent with anticancer activity. This compound has been shown to be highly active against herpes simplex virus type 1 (HSV1) in vitro. The mechanism of action is not yet fully understood but may involve modification of the viral DNA polymerase.</p>Formule :C36H41N3O8Degré de pureté :Min. 95%Masse moléculaire :643.73 g/mol5,6-Diaminouracil
CAS :5,6-Diaminouracil is a nitrogen-containing heterocyclic compound that inhibits bacterial enzymes. 5,6-Diaminouracil is used as a pharmaceutical preparation for the treatment of cancer, and has been shown to be effective against various cancers, including colon cancer and breast cancer. 5,6-Diaminouracil can inhibit the growth of cells by binding to DNA and inhibiting DNA synthesis. This drug also has potent antitumor activity. 5,6-Diaminouracil has been used in analytical chemistry as an analytical method for determining the purity of products such as pharmaceuticals or dyes. The potency of this drug was determined electrochemically using cyclic voltammetry and it was found to have a constant inhibitory effect on tumor cell growth at low concentrations.Formule :C4H7ClN4O2Degré de pureté :Min. 95%Masse moléculaire :178.58 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite
CAS :9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a novel nucleoside analogue that has shown to be effective against cancer. This product can also be used as an antiviral and antifungal agent. It is synthesized from 2,3,4,5,6-pentaacetoxybenzaldehyde and chloroacetamide. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a high quality product that is made of Ribonuclesides, Synthetic Monophosphate Nucleosides Diphosphate Modified Deoxyribonucleosides Activator.Formule :C44H53FN7O8PDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :857.93 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate
CAS :5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation. AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.Formule :C9H17N4O14P3Degré de pureté :Min. 95%Masse moléculaire :498.17 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite
CAS :2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite is a modified nucleoside that has antiviral and anticancer properties. It is synthesized by the reaction of 2'-O-tert-butyldimethylsilyl-5'-O-DMT (2,6-dimethoxytrityl) with 3 methyluridine. The compound has been shown to be an activator for DNA polymerase, ribonucleases and deoxyribonucleases in vitro. It also inhibits tumor cell proliferation and induces apoptosis in cultured cells. This compound is a high quality product with CAS number 179762-50-6 and is available at high purity.Formule :C46H63N4O9PSiDegré de pureté :Min. 95%Masse moléculaire :875.07 g/molO6-Phenyl-2'-deoxyinosine
CAS :<p>O6-Phenyl-2'-deoxyinosine is a high purity, modified nucleoside that is a novel anticancer agent. It is used as a phosphoramidite in the synthesis of DNA and RNA. It has been shown to have cytotoxic effects against tumor cells and enhances the efficacy of chemotherapy. O6-Phenyl-2'-deoxyinosine has also been shown to be an activator of transcription factors, including NF-κB, AP-1, and STAT3.</p>Formule :C16H16N4O4Degré de pureté :Min. 95%Masse moléculaire :328.32 g/mol7-Deazapurine
CAS :<p>7-Deazapurine is a cytostatic agent that inhibits the polymerase chain reaction by competitive inhibition of the incorporation of nucleotides into DNA. It has potent antitumor activity and significant cytotoxicity, which are due to its ability to inhibit DNA synthesis and cell division. 7-Deazapurine is also a nucleophilic compound that reacts with hydroxyl groups in DNA. The hydrolysis of 7-deazapurine by hydroxylases can be prevented by addition of high salt or trifluoroacetic acid, but this does not seem to affect its cytotoxic effects.<br>7-Deazapurine has been shown to have significant cytotoxicity against miapaca-2 cells and other cancer cell lines.</p>Formule :C6H5N3Degré de pureté :Min. 95%Masse moléculaire :119.12 g/molN6-Benzoyl-2',3'-dideoxyadenosine
CAS :N6-Benzoyl-2',3'-dideoxyadenosine is a nucleoside analog that inhibits the growth of Mycobacterium tuberculosis by preventing DNA replication. It is also a potent inhibitor of DNA synthesis, and binds to the beta-subunit of bacterial RNA polymerase, leading to inhibition of transcription. N6-Benzoyl-2',3'-dideoxyadenosine has shown in vitro activity against Mycobacterium tuberculosis and other bacteria that have been found to be resistant to conventional antibiotics.Formule :C17H17N5O3Degré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :339.36 g/mol2'-Deoxy-5-fluoroadenosine
<p>2'-Deoxy-5-fluoroadenosine is a nucleoside that is used in the synthesis of DNA and RNA. It has antiviral activity and can be used as an anticancer agent. This nucleoside is synthesized by reacting 2'-deoxyadenosine with 5-fluorouracil in a high-quality, high purity environment under stringent conditions. 2'-Deoxy-5-fluoroadenosine has also been shown to have antiretroviral activity against HIV and hepatitis B virus.</p>Degré de pureté :Min. 95%2'-O-Allylguanosine
CAS :<p>2'-O-Allylguanosine is an intermediate in the synthesis of 2,6-diaminopurine riboside. It is synthesized from allyl chloride and guanosine by an allylation reaction. The yield for this reaction is high, which makes it a useful synthon. Deamination of the product yields 2'-O-allylguanosine 5'-monophosphate, which can be converted to 2',6-diaminopurine riboside by hydrolysis with phosphoric acid. This intermediate is used in research on nucleic acids sequences and hydrogen bonding.</p>Formule :C13H17N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :323.3 g/molN4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite
<p>N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite is a novel nucleoside designed for DNA activation. It has high quality and high purity, which are essential for pharmaceutical and analytical applications. This product is used in the synthesis of DNA, antiviral drugs, and anti-cancer agents. N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT b -D -arabinofuranosyl)cytosine 3'-CE phosphoramidite can be used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides.</p>Formule :C22H34N5O8PDegré de pureté :Min. 95%Masse moléculaire :527.51 g/molPyrrolo-2’-deoxycytidine 3’-CE phosphoramidite
CAS :A fluorescent analogue of deoxycytidine. Used for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Emission max is at 473nm.Formule :C42H50N5O7PDegré de pureté :Min. 95%Masse moléculaire :767.8 g/mol2',3',5'-Tri-O-benzoyl-2-thiouridine
CAS :<p>2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).</p>Formule :C30H24N2O8SDegré de pureté :Min. 95%Masse moléculaire :572.59 g/mol2',3'-Didehydro-2',3'-dideoxyuridine
CAS :<p>2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.</p>Formule :C9H10N2O4Degré de pureté :Min. 95%Masse moléculaire :210.19 g/mol2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate
2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is a modified nucleotide analog that is used as an antiviral agent. It inhibits the synthesis of viral DNA by competitively inhibiting the incorporation of deoxyribonucleoside triphosphates into the growing DNA chain. 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is phosphorylated to 2-[2-(2,6,8,10,12,14,16,-doxohexadecyl)-1H--imidazo[4,5--c]pyridine--1--carboxylic acid]ethanol phosphate in vivo and this active form inhibits human immunodeficiency virus type 1 (HIV1) replication in vitro with an IC 50 of 0.06 μM.Formule :C10H15ClN5O13P3Degré de pureté :Min. 95%Masse moléculaire :541.63 g/molGuanosine-5'-carboxylic acid
CAS :Guanosine-5'-carboxylic acid (GCA) is a nucleotide that interacts with mammalian cells. It reacts in a vessel to form the antigen, which can then be detected using an antibody. The conformational properties of this molecule are important for its function, and it has been shown to be effective against cancer cells in vivo. GCA has also been shown to interact with toll-like receptor 2 and induce an antibody response.Formule :C10H11N5O6Degré de pureté :Min. 95%Masse moléculaire :297.22 g/mol
