Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3573 produits trouvés pour "Nucléosides"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
2',3'-Dideoxy-5'-O-DMT-cytidine
CAS :2',3'-Dideoxy-5'-O-DMT-cytidine is a chemically modified cytidine nucleoside which can be used in synthetic chemistry, especially in nucleic acid synthesis. A dimethoxytrityl (DMT) protecting group is attached to the 5'-oxygen of the sugar. This is not biologically active, but it’s commonly used in solid-phase oligonucleotide synthesis to protect the 5' end during step-by-step DNA or RNA construction.Formule :C30H31N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :513.6 g/molDMT-2'-OMe-pseudouridine phosphoramidite
DMT-2'-OMe-pseudouridine phosphoramidite is an antiviral, anticancer, and DNA synthesis inhibitor. It has been used in the synthesis of oligonucleotide probes for sequencing and hybridization studies. DMT-2'-OMe-pseudouridine phosphoramidite is a modified nucleoside that is used as a building block for the synthesis of DNA. This compound is synthesized from 2'-deoxy-5-methyluridine and dimethoxytrityl chloride. DMT-2'-OMe-pseudouridine phosphoramidite inhibits the synthesis of RNA and DNA by binding to ribonucleotides and deoxyribonucleotides during the polymerization reaction, thereby blocking the progression of the reaction.Degré de pureté :Min. 95%8-Aza-6-hydroxy-2-mercaptopurine
CAS :8-Aza-6-hydroxy-2-mercaptopurine (8AzaMP) is a novel nucleoside analog that is an activator of the thymidylate synthase enzyme. It has been shown to inhibit the replication of many DNA viruses and to inhibit tumor growth in animal models. 8AZA MP has been evaluated in Phase I and II clinical trials for the treatment of various cancers, including malignant melanoma, renal cell carcinoma, and chronic lymphocytic leukemia. This drug has also shown promise as a chemotherapeutic agent for AIDS patients with HIV infection or AIDS-related complex.Formule :C4H3N5OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :169.17 g/mol5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]uridine
CAS :5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]uridine (5MeUrd) is a diphosphate nucleoside that has been modified with a methyl group on the 2′ position. It is a novel, high quality, synthetic nucleoside with antiviral and anticancer properties. 5MeUrd is structurally similar to uridine and cytidine, which are deoxyribonucleosides. The phosphoramidite of 5MeUrd can be used for the synthesis of DNA, RNA, or monophosphate nucleosides in vitro. 5MeUrd has been shown to inhibit human leukemia cells and cancer cell lines in vitro by inhibiting DNA synthesis.Formule :C13H19N3O7Degré de pureté :Min. 95%Masse moléculaire :329.31 g/molCytidine 5'-monophosphate free acid
CAS :Cytidine 5'-monophosphate is a nucleotide that is important in the synthesis of DNA and RNA. It is a precursor to uridine monophosphate (UMP) and uridylic acid (UDP). Cytidine 5'-monophosphate has been found to inhibit the growth of antibiotic-resistant strains of bacteria, such as those resistant to ampicillin, chloramphenicol, tetracycline, kanamycin, and streptomycin. Cytidine 5'-monophosphate also has inhibitory properties against energy metabolism and protein oxidation in bowel disease. This nucleotide has been shown to increase the rate constant for polymerase chain reaction (PCR) by up to 10-fold.Formule :C9H14N3O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :323.2 g/molN6-Acetyladenosine
CAS :N6-Acetyladenosine is a nucleoside that belongs to the group of N-acetylated adenosines. It is found in thermophilic organisms and has been shown to be involved in optimal growth. N6-Acetyladenosine has also been found to be an important part of the coding and population modifications of crenarchaeota, archaeal organisms that are phylogenetically related to methanogens. Unfractionated populations of methanogen contain both N6-acetyladenosine residues and other modified adenosines, with each organism differing in the types of modifications they contain. Transfer of these modified adenosines from one organism to another can lead to changes in their coding and population modifications.Formule :C12H15N5O5Degré de pureté :Area-% Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :309.28 g/mol2',3'-Dideoxy-2',3'-didehydroadenosine
CAS :2′,3′-Dideoxy-2′,3′-didehydroadenosine, abbreviated to d4A, is a synthetic purine nucleoside analog. Possible applications are its use to study antiviral activity.Formule :C10H11N5O2Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :233.23 g/mol3'-Azido-3'-deoxy-b-L-cytidine
CAS :3'-Azido-3'-deoxy-b-L-cytidine is a novel nucleoside that has been shown to be an activator of the ribonuclease activity of purified RNase A in vitro. This product is suitable for use in synthesis of oligodeoxynucleotides and phosphoramidites. 3'-Azido-3'-deoxy-b-L-cytidine can be used as a potential anticancer drug or antiviral agent.Degré de pureté :Min. 95%5’-O-Acetyl-5-acetyloxymethyluridine
CAS :5’-O-Acetyl-5-acetyloxymethyluridine is an activated nucleoside that is a phosphoramidite. It can be used in the synthesis of oligonucleotides and has antiviral, anticancer, and antiretroviral activities. This product is a novel compound that can be used to synthesize high quality deoxyribonucleosides and diphosphate ribonucleosides. 5’-O-Acetyl-5-acetyloxymethyluridine is an activator for DNA polymerases and RNA polymerases with a high degree of purity.Formule :C14H18N2O9Degré de pureté :Min. 95%Masse moléculaire :358.3 g/molN2,2'-O-Dimethylguanosine
CAS :N2,2'-O-Dimethylguanosine is a nucleoside that belongs to the category of modified bases. It is synthesized from adenosine and a methyl group by a mutant strain of Escherichia coli. N2,2'-O-Dimethylguanosine can be identified by its characteristic UV-visible spectrum and high retention time on chromatographic columns. It has been shown to inhibit translation in E. coli at concentrations as low as 1 mM and also inhibits growth rate at concentrations as low as 2 mM. The chemical structure of this compound is similar to that of guanosine, but it contains an extra methyl group on its 2' carbon atom. This chemical modification may result in changes in the way the molecule interacts with other molecules or how it functions in the cell. N2,2'-O-Dimethylguanosine was first identified from a mutant strain of Escherichia coli that had been subjected to mutagenesisFormule :C12H17N5O5Degré de pureté :Min. 95%Masse moléculaire :311.29 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is a nucleotide that is used in the synthesis of DNA. It is an organic compound consisting of a molecule with a phosphate group at one end and a ribose sugar at the other. 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is synthesized on a solid support by reacting nucleophilic reagents with the ribonucleoside. This drug has antineoplastic effects, inhibiting cancer cell growth by interfering with the production of ribonucleic acid (RNA) and protein synthesis. Hydrolysis of this drug releases fluorouracil, which inhibits thymidylate synthase, preventing the conversion of dUMP to dTMP, and thus blocking DNA synthesis.
Formule :C39H46FN4O8PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :748.78 g/molN6,N6,2'-O-Trimethyladenosine
CAS :N6,N6,2'-O-Trimethyladenosine is a nucleoside that is found in small quantities in human tissues. It is synthesized by the enzyme polymerase from adenosine and S-adenosyl-L-methionine. N6,N6,2'-O-Trimethyladenosine is structurally similar to guanosine and cytidine and can be modified by nature or synthetic strategies. N6,N6,2'-O-Trimethyladenosine has been shown to have effects on fertility and may be involved in epigenetics as well as tuberculosis. Its role as an epigenetic marker for gene regulation has not been fully determined.Formule :C13H19N5O4Degré de pureté :Min. 88 Area-%Couleur et forme :White PowderMasse moléculaire :309.32 g/mol4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine
CAS :4’,5’-Didehydro-2’-O-(2-methoxyethyl)-5-methyluridine (DdeO) is a novel phosphoramidite that is synthesized from 2’,3’-dideoxycytidine. It is used in DNA synthesis and as an antiviral and anticancer agent. DdeO has shown to be a potent activator of the p53 tumor suppressor gene and inhibits the proliferation of human cancer cells by inhibiting the activity of DNA polymerase alpha. DdeO also inhibits viral replication by interfering with viral DNA synthesis.Degré de pureté :Min. 95%N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite
CAS :Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite, also known as 2'-fluoro-dA CEP, is a modified adenosine with a fluorine atom in the 2’ position to enable the synthesis of non-natural fluorine containing oligonucleotides. Nucleoside phosphoramidites are typically modified by displacement of the diisopropylamine group with the 5’ hydroxyl of the next nucleoside in the presence of an azole catalyst such as 1H-tetrazole or 4,5-dicyanoimidazole. 2'-Fluoro-dA CEP has been used in the synthesis of phosphorothioate oligonucleotides that were highly nuclease resistant yet retained exceptional binding affinity to the RNA targets.Formule :C47H51FN7O7PDegré de pureté :97%Couleur et forme :PowderMasse moléculaire :875.95 g/molN6-Benzoyl-2'-O-benzyl-5'-O-DMT-adenosine
CAS :N6-Benzoyl-2'-O-benzyl-5'-O-DMT-adenosine is a novel nucleoside with anticancer and antiviral properties. It is a phosphoramidite that can be used for the synthesis of DNA, RNA, and other nucleosides. N6-Benzoyl-2'-O-benzyl-5'-O-DMT-adenosine has been shown to inhibit the growth of cancer cells by preventing RNA synthesis and DNA replication. This chemical also has antiviral effects against HIV and can inhibit the replication of herpes simplex virus type 1. The chemical is highly soluble in water, methanol, ethanol, acetone, chloroform, ethyl ether and acetonitrile.Formule :C45H41N5O7Degré de pureté :Min. 95%Masse moléculaire :763.84 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It is synthesized from 5'-O-trityluridine and 2'-deoxyribonucleosides. This nucleoside has antiviral and anticancer properties, which are due to the fact that it inhibits viral replication by inhibiting DNA polymerase and prevents cell proliferation. 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a high purity, high quality product that can be used in DNA synthesis and cancer treatment.Formule :C43H57N4O7PSiDegré de pureté :Min. 95%Masse moléculaire :801.02 g/mol2',5'-Dideoxyuridine
CAS :2',5'-Dideoxyuridine is a synthetic nucleoside analog derived from uridine, one of the four standard nucleosides found in RNA. It is chemically modified by the removal of hydroxyl (–OH) groups at the 2' and 5' positions of the sugar, altering its ability to participate in RNA or DNA chain formation.
Formule :C9H12N2O4Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :212.21 g/mol5’(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine is a nucleoside that has been shown to activate both ribonucleosides and deoxyribonucleosides. 5’(R)-C-Methyl-5-fluorouridine is a novel nucleotide with the potential to be used in anticancer therapy. It can be used as a building block for DNA synthesis, as well as being able to act as an anticancer drug by inhibiting the growth of cancer cells. This product is made from high quality raw materials and has a purity of at least 98%. It is available in powder form.Degré de pureté :Min. 95%1', 2', 3', 4', 5'- ¹³C5-Adenosine
CAS :1', 2', 3', 4', 5'- ¹³C5-Adenosine is adenosine which has all five carbon atoms of the ribose sugar replaced with the stable isotope carbon-13 (^13C). Possible applications are in proteomics studies.Formule :C5C5H13N5O4Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :272.2 g/molUridine-5'-triphosphate trisodium salt
CAS :P2Y receptor agonist; precursor in RNA biosynthesisÂFormule :C9H12N2Na3O15P3Degré de pureté :(31P Nmr) Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :550.09 g/mol
![5-Methyl-2′-O-[2-(methylamino)-2-oxoethyl]uridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNM182886.webp&w=3840&q=75)
