Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3570 produits trouvés pour "Nucléosides"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
2-Hydrazinoadenosine
CAS :2-Hydrazinoadenosine is an active analogue of adenosine. It is a potent agonist for the adenosine receptor subtypes A1 and A2A with high affinity. 2-Hydrazinoadenosine has been shown to inhibit cardiac contractility in animal models, as well as to produce hypotension, bradycardia, and bronchodilation in humans. This drug also has a functional effect on the heart by binding to adenosine receptors, which leads to the inhibition of catecholamine release. This drug is used clinically as an antiarrhythmic agent and a vasodilator in coronary artery disease.
Formule :C10H15N7O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.27 g/molAdenosine 5'-diphosphate bis(cyclohexylammonium) salt
CAS :Adenosine 5'-diphosphate bis(cyclohexylammonium) salt is a novel antiviral agent that has been shown to be an activator of the adenylate cyclase enzyme. It also inhibits DNA and RNA synthesis in viruses, which prevents viral replication. Adenosine 5'-diphosphate bis(cyclohexylammonium) salt is active against cancer cells and has been shown to inhibit tumor growth and prolong survival in animal models. This compound can be synthesized by reacting the monophosphate with phosphoramidites or deoxyribonucleosides.Formule :C10H15N5O10P2·2C6H13NDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :625.55 g/mol2'-Amino-2'-deoxyadenosine-5'-triphosphate sodium salt - aqueous solution
CAS :2'-Amino-2'-deoxyadenosine-5'-triphosphate sodium salt - aqueous solution is a modified ATP analog, where the ribose has a 2'-amino substitution. This compound has potential research applicationsFormule :C10H17N6O12P3·xNaDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :506.2 g/molN3-Methylthymidine
CAS :N3-Methylthymidine is a metalloprotease inhibitor that has been shown to inhibit the activity of epidermal growth factor (EGF). N3-Methylthymidine is also an effective inhibitor of HIV infection. The inhibitory effect on HIV infection is due to the competitive inhibition of viral protease and subsequent degradation of viral proteins. N3-Methylthymidine inhibits the synthesis and release of infectious herpes simplex virus particles. This drug also inhibits the growth of human tumor cells in culture by inhibiting cell proliferation, most likely due to its ability to inhibit EGF. An analytical method for determining the concentration of this drug in plasma using chemical ligation has been developed.Formule :C11H16N2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :256.26 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite
CAS :2'-Deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is an antibiotic that inhibits bacterial growth by binding to DNA, preventing transcription and replication. It has been shown to have antibacterial activity against a wide variety of bacteria, including staphylococcus, tuberculosis and vibrio cholerae. 2'-Deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a chemotaxis regulator in the biosynthetic pathway of certain bacteria. These bacteria use this compound as a precursor for the production of other antibiotics. This antibiotic binds to the regulatory site on bacterial chemotaxis and inhibits the response to attractants such as sugars or amino acids.Formule :C39H47N4O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :730.81 g/molUridine 3'-monophosphate disodium salt
CAS :Uridine 3'-monophosphate disodium salt is a nucleotide that is part of the pyrimidine family. It is synthesized from uridine and phosphoric acid in a reaction that requires hydrogen bonding and the presence of an enzyme. Uridine 3'-monophosphate disodium salt has been shown to inhibit the production of eosinophil cationic protein, which may be due to its ability to denature proteins. This drug also has an effect on the synthesis of proteins by inhibiting enzymes such as acetylcholinesterase and catalase. The synthesis of glycosidic bonds is also inhibited, which may lead to an increase in body mass index (BMI).Formule :C9H11N2Na2O9PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :368.15 g/mol2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate
CAS :2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a nucleoside that is used as an antiviral agent in the treatment of herpes zoster and varicella zoster. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis. 2'-Deoxycytidine-5'-diphosphate trisodium salt hydrate is a novel nucleotide analogue that has been modified to improve its stability, solubility and bioavailability. It can be used as a starting material for the synthesis of phosphoramidites by reacting with phosphorous pentoxide at elevated temperatures and pH. CAS No. 151151-32-5Formule :C9H12N3O10P2·Na3Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :453.12 g/mol2'-Deoxyinosine-5'-monophosphate disodium salt
CAS :2'-Deoxyinosine-5'-monophosphate disodium salt is a synthetic nucleoside, phosphoramidite, and diphosphate that is used in the synthesis of DNA. It has been shown to have antiviral effects against HIV and herpes simplex virus type 2 (HSV-2). This drug also has anticancer activity and is an activator of novel nucleosides.Formule :C10H11N4Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :376.17 g/mol5’-ODMT cET-uridine 3’-OCE amidite
CAS :5’-ODMT cET-uridine 3’-OCE amidite is a bicyclic nucleoside that is commonly known as BNA for bicyclic nucleic acid or LNA for locked nucleic acid. It comprises a bridge between the 4' and 2' carbon atoms to lock the ribose ring into a fixed configuration. The BNA or LNA incorporated oligonucleotides are useful to regulate gene expression via antisense mechanisms.Formule :C41H49N4O9PMasse moléculaire :772.82 g/molCytarabine
CAS :Formule :C9H13N3O5Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :243.222'-Deoxy-4-thiouridine
CAS :2'-Deoxy-4-thiouridine is a pyrimidine nucleoside for a range of applications
Formule :C9H12N2O4SDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :244.27 g/mol2,4-Diamino-6-hydroxypyridine sulphate
CAS :2,4-Diamino-6-hydroxypyridine sulphate is a nucleoside for use in research applicationsFormule :C4H6N4O•(H2SO4)xDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :224.2 g/mol5’-ODMT-cET-5-methyluridine 3’-OCE amidite
CAS :5’-ODMT-cET-5-methyluridine 3’-OCE amidite is a bicyclic nucleoside that is commonly known as BNA for bicyclic nucleic acid or LNA for locked nucleic acid. It comprises a bridge between the 4' and 2' carbon atoms to lock the ribose ring into a fixed configuration. The BNA or LNA incorporated oligonucleotides are useful to regulate gene expression via antisense mechanisms.Formule :C42H51N4O9PMasse moléculaire :786.86 g/molCytidine 5'-diphosphocholine
CAS :Cytidine 5'-diphosphocholine is a nucleotide that is a precursor of uridine 5'-triphosphate and cytidine 5'-monophosphate, which are important for DNA synthesis. Cytidine 5'-diphosphocholine is used in the preparation of samples for experiments. This compound has been shown to induce neuronal death in an experimental model. It has also been shown to inhibit polymerase chain reactions and affect the activity of enzymes such as alpha-7 nicotinic acetylcholine receptors and glutamate decarboxylase. Cytidine 5'-diphosphocholine has been found to have no effect on basic fibroblast cells, but it does have physiological effects on human erythrocytes.Formule :C14H26N4O11P2Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :488.32 g/mol5-Fluorouridine-5'-triphosphate sodium salt
CAS :5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.Formule :C9H14N2O15P3FDegré de pureté :Min. 95%Masse moléculaire :502.13 g/moldNTP pre-mixes, 10 mM aqueous solution
CAS :dATP, dTTP, dCTP and dGTP pre-mixed in a single vialFormule :C10H16N5O12P3Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :491.18 g/moldNTP bundle, 4 x 100mM aqueous solution
CAS :Each dNTP supplied in a separate vialDegré de pureté :Min. 99 Area-%Couleur et forme :Clear Liquid2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium
CAS :2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium is a modified nucleoside analog where the base is cytosine, the sugar is deoxyribose with a fluoro modification at the 2' position, and the molecule is phosphorylated at the 5' position with a triphosphate group.Formule :C9H11FLi4N3O13P3Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :508.88 g/molGuanosine 5'-monophosphate disodium salt
CAS :Guanosine 5'-monophosphate disodium salt (GMPDS) is an antiviral agent that inhibits the synthesis of viral nucleic acids by competitive inhibition of the enzyme ribonucleotide reductase. GMPDS has been shown to inhibit the replication of a number of RNA viruses, including influenza A and B, herpes simplex virus type 1, and human immunodeficiency virus type 1. This drug also has been shown to decrease cyclic adenosine monophosphate (cAMP) levels in cells by inhibiting phosphodiesterase activity. GMPDS is used for treatment of infectious diseases such as influenza A, herpes, and HIV-1.Formule :C10H12N5Na2O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :407.18 g/mol2'-Deoxy-N2-phenoxyacetylguanosine
CAS :2'-deoxy-N2-phenoxyacetylguanosine is a synthetic nucleoside that is used as a substrate in experiments to study the properties of guanine. The compound can be synthesized by the reaction of 2'-deoxy-N2-phenoxyacetaldehyde with guanine. The synthesis starts with the condensation of 2'-deoxyribose and N2-phenoxyacetaldehyde, followed by the oxidation of the resulting anhydride to give aldehyde, which reacts with guanine to form a Schiff base. This then undergoes hydrolysis to yield 2'-deoxy-N2-phenoxyacetylguanosine.Formule :C18H19N5O6Degré de pureté :Min. 95%Masse moléculaire :401.38 g/mol
