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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride


    <p>3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is a nucleoside that belongs to the class of diphosphates. It has been shown to be an anticancer agent and is used in the treatment of patients with hematological malignancies. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is synthesized from 5'-deoxyuridine monophosphate and amidites, which are modified phosphoramidites. This compound can be used as a building block for DNA synthesis by incorporating into a growing chain, or as an activator for DNA polymerases. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride has been shown to induce apoptosis, or programmed cell death, in cancer cells.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND168378

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  • 5'-Deoxy-5-fluorocytidine

    CAS :
    <p>5'-Deoxy-5-fluorocytidine is a cytosolic nucleoside analogue that is phosphorylated by cellular enzymes to the active form 5'-deoxy-5-fluorouridine monophosphate. It is a prodrug, which is activated in the body to release 5-FU and inhibits the growth of cancer cells. 5'-Deoxy-5-fluorocytidine has been shown to be effective against metastatic colorectal cancer in humans and resistant breast cancer in mice. The drug can also be used as an oral prodrug for 5-FU, which has a wide therapeutic index and low toxicity. Studies have shown that it selectively inhibits proliferation of solid tumours through inhibition of protein synthesis and cell division. The drug also has antiangiogenic effects, which are thought to contribute to its antitumor activity.</p>
    Formule :C9H12FN3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :245.21 g/mol

    Ref: 3D-ND04700

    10g
    254,00€
    25g
    477,00€
    50g
    679,00€
    100g
    965,00€
  • 9-(2’-Deoxy-2’-fluoro-arabinofuranosyl)adenine 5’-triphosphate triethyl ammonium salt


    <p>Ai Product Descriptions 50 Creative</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162976

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  • N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite


    <p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a novel nucleoside that has been shown to inhibit the growth of cancer cells in vitro. It is an analogue of cytidine and inhibits DNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This drug also inhibits the synthesis of viral RNA in cells infected with human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV-1). N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-thiophosphoramidite is a phosphoramidite that is synthesized from 2,4,6-trichlorobenzoyl chloride, 5'-O-[(N,N-diisoprop</p>
    Formule :C50H51N4O8PS2
    Degré de pureté :Min. 95%
    Masse moléculaire :931.07 g/mol

    Ref: 3D-NB46055

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  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite

    CAS :
    <p>The 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is an oligomer with a modified nucleoside. The modification of the nucleoside has been shown to be more efficient than other modifications, such as fluorine or bromine substitutions. This product is used in the synthesis of DNA and RNA oligomers. The coupling efficiency is high and can be used for ligand binding studies.</p>
    Formule :C50H68N7O9PSi
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :970.18 g/mol

    Ref: 3D-PB08938

    5g
    344,00€
    10g
    543,00€
    25g
    1.137,00€
    50g
    1.819,00€
    100g
    2.952,00€
  • 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine

    CAS :
    <p>5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is a novel nucleoside that has antiviral and anticancer properties. It is an activator of the monophosphate phosphoramidites and has been shown to inhibit the growth of cancer cells in vitro. 5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluorouridine is also able to inhibit viral replication by terminating cellular DNA synthesis at the level of RNA polymerase II. This results in the synthesis of defective viral genomes that are unable to produce new viruses, thereby preventing viral spread.</p>
    Formule :C19H19FN2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :406.36 g/mol

    Ref: 3D-NT144914

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  • 5-(2-Amino-2-oxoethyl)-2-thiouridine

    CAS :
    <p>5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.</p>
    Formule :C11H15N3O6S
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :317.32 g/mol

    Ref: 3D-NA159483

    5mg
    486,00€
    10mg
    806,00€
    25mg
    1.762,00€
  • 3’-Azido-3’-deoxy-5-fluoro-b-L-uridine

    CAS :
    <p>3’-Azido-3’-deoxy-5-fluoro-b-L-uridine is a novel, activator ribonucleoside that is an analog of the natural nucleoside uridine. It has high quality and purity. This compound is used to synthesize deoxyribonucleosides, diphosphate, phosphoramidites, modified, anticancer and antiviral agents.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA163021

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  • Cytidine 5'-monophosphate disodium salt

    CAS :
    <p>Cytidine 5'-monophosphate disodium salt (CMPDS) is a prodrug that is converted to cytidine 5'-monophosphate, an active form, in the acidic environment of cancer cells. CMPDS has been shown to inhibit the growth of squamous carcinoma and other solid tumours by binding to survivin, which regulates cell growth and apoptosis. CMPDS also inhibits the activity of matrix metalloproteinases-9 (MMP-9), an enzyme that promotes tumor growth by breaking down connective tissue. This drug can be used as a therapeutic agent for treatment of congestive heart failure due to its ability to increase mitochondrial membrane potential and decrease myocardial infarct size.</p>
    Formule :C9H12N3Na2O8P
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :367.16 g/mol

    Ref: 3D-NC05637

    1kg
    917,00€
    50g
    273,00€
    100g
    363,00€
    250g
    494,00€
    500g
    764,00€
  • 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt


    <p>2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be active against herpes simplex virus type 1 and cytomegalovirus in cell culture. It also inhibits the replication of human immunodeficiency virus type 1 in cell culture. 2’-O,4’-C-Methyleneadenosine 5’-monophosphate triethyl ammonium salt is a phosphoramidite nucleoside analog that can be used as an activator for DNA synthesis. It can also serve as a building block for the synthesis of deoxyribonucleosides and ribonucleosides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM163176

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  • 2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt


    <p>2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt (2'F-ATP) is a nucleoside analog that inhibits viral DNA polymerase and induces apoptosis in cancer cells. It is a novel, modified nucleotide that can be phosphorylated to 2'F-dATP, 2'F-AMP, or 2'F-GMP. The phosphate group in 2'F-ATP is replaced by a thiophosphate group, which increases the stability of the molecule and prevents it from being hydrolyzed by phosphatases. This makes it an effective activator for DNA synthesis reactions.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND164929

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  • 2'-C-Methylguanosine 5'-diphosphate triethylammonium salt


    <p>2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in research</p>
    Formule :C11H16N5O11P2·C18H45N3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :759.79 g/mol

    Ref: 3D-NM10849

    1mg
    367,00€
    2mg
    607,00€
    5mg
    1.042,00€
    10mg
    1.626,00€
  • 2'-Deoxyisocytidine

    CAS :
    <p>2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.</p>
    Formule :C9H13N3O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :227.22 g/mol

    Ref: 3D-ND30844

    50mg
    277,00€
    100mg
    434,00€
    250mg
    657,00€
  • E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine

    CAS :
    <p>E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.</p>
    Formule :C13H16N2O7
    Degré de pureté :Min. 95%
    Couleur et forme :White to off-white solid.
    Masse moléculaire :312.28 g/mol

    Ref: 3D-NC08275

    500mg
    134,00€
  • Guanosine 5'-O-(2-thiodiphosphate) trilithium salt

    CAS :
    <p>Guanosine 5'-O-(2-thiodiphosphate) trilithium salt (GTPTS) is a membrane-permeable molecule that hyperpolarizes cells by inhibiting the movement of ions through the cell membrane. GTPTS is activated by extracellular calcium and potassium ions, which are involved in signal transduction pathways. It has been shown to inhibit the release of neurotransmitters, such as acetylcholine, dopamine, serotonin, and norepinephrine. GTPTS also blocks voltage-gated sodium channels, which leads to a reduction in neuronal excitability. The drug has been shown to have analgesic effects in animal models of pain and can be used to treat chronic pain due to nerve damage.</p>
    Formule :C10H12Li3N5O10P2S
    Degré de pureté :Min. 85 Area-%
    Couleur et forme :Powder
    Masse moléculaire :477.06 g/mol

    Ref: 3D-NG09615

    2mg
    224,00€
    5mg
    356,00€
    10mg
    552,00€
    25mg
    1.005,00€
    50mg
    1.667,00€
  • 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine


    <p>2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Sp-oxazaphospholidine is a DNA synthesis inhibitor. It is modified with a 2'-deoxy-5'-O-dimethoxytrityl group on the 2' position and an N2,N2-(isobutyryl) guanine moiety on the 5' position. This compound inhibits DNA synthesis by forming a covalent bond to the 3' phosphate of DNA. This product is synthesized in high purity and quality. It can be used for anticancer research or as an activator for phosphoramidites for the synthesis of DNA. CAS No.: 63787-03-6</p>
    Degré de pureté :Min. 95%

    Ref: 3D-PD170431

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  • 2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine

    CAS :
    <p>2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxy-4’,5’-Didehydrouridine is a phosphoramidite that is used in the synthesis of DNA, RNA and nucleotide analogues. It has antiviral and antitumor properties and can be used for the treatment of leukemia. 2’,3’-Bis-O-tert-butyldimethylsilyl-5’-deoxyuridine is an activator for ribonucleotides and deoxyribonucleotides. It also has anticancer properties due to its ability to inhibit DNA replication, which may lead to apoptosis or cell death.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB163070

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  • 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine

    CAS :
    <p>3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine is an antiviral drug. It is a modified nucleoside with phosphoramidite and azido groups. This product can be used as an activator for DNA synthesis, in anticancer drug development, as well as in the treatment of HIV. 3'-Azido-3'-deoxy-5-fluoro-b-L-cytidine has been shown to inhibit the growth of human tumor cells by inhibiting protein synthesis and enhancing the production of reactive oxygen species (ROS). It also inhibits the activity of ribonucleotide reductase, which is a critical enzyme for DNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA163024

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  • 2'-Deoxy-N6-methyladenosine

    CAS :
    <p>2'-Deoxy-N6-methyladenosine (2DMA) is a nucleoside that has been found to inhibit the phosphorylation of p2y receptors in rat kidney cells. 2DMA inhibits the production of collagen, which may have a matrix effect on cells. Studies have shown that 2DMA can be used as a sample preparation reagent for nuclear DNA. It has also been shown to be effective at inhibiting transcription and replication of human mitochondrial DNA.</p>
    Formule :C11H15N5O3
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :265.27 g/mol

    Ref: 3D-ND06386

    1g
    838,00€
    2g
    1.195,00€
    100mg
    245,00€
    250mg
    383,00€
    500mg
    508,00€
  • 2'-Deoxyinosine

    CAS :
    <p>2'-Deoxyinosine is an antimicrobial peptide that has been shown to have potent activity against Gram-positive bacteria, including Staphylococcus aureus. 2'-Deoxyinosine binds to the 3′-hydroxyl group of nucleic acid, preventing DNA replication and transcription. This binding also prevents ribosomal RNA from binding to the ribosome, inhibiting protein synthesis. 2'-Deoxyinosine has been detected using a highly sensitive optical sensor and can be used as a model system for studying the interaction between dsDNA duplexes and other biomolecules. The pharmacokinetic properties of this molecule have been determined in rats by measuring its concentration in serum over time after injection. These data were then used to determine the amount of 2'-deoxyinosine that was needed to inhibit bacterial growth in water samples.</p>
    Formule :C10H12N4O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :252.23 g/mol

    Ref: 3D-ND05750

    25g
    254,00€
    50g
    467,00€
    100g
    764,00€
    250g
    1.592,00€
    500g
    2.806,00€
  • N4-Benzoyl-5'-O-DMT-5-methylcytidine

    CAS :
    <p>N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.</p>
    Formule :C38H37N3O8
    Degré de pureté :Min. 95%
    Couleur et forme :White Solid
    Masse moléculaire :663.73 g/mol

    Ref: 3D-NB09436

    1g
    315,00€
    2g
    454,00€
    250mg
    134,00€
    500mg
    179,00€
  • 2'-Deoxy-5'-DMT(2-E-bromoethenyl)uridine 3'-CE phosphoramidite

    CAS :
    <p>2'-Deoxy-5'-DMT(2-E-bromoethenyl)uridine 3'-CE phosphoramidite is a synthesized nucleoside used for the preparation of oligonucleotides. It is used in the synthesis of oligonucleotides as an activator, monophosphate, or nucleotide. 2'-Deoxy-5'-DMT(2-E-bromoethenyl)uridine 3'-CE phosphoramidite is a novel and high quality chemical that has not been previously reported. It is typically stored at -20℃. 2'-Deoxy-5'-DMT(2-E-bromoethenyl)uridine 3'-CE phosphoramidite may be incompatible with strong oxidizing agents, strong acids, strong bases, and metal ions.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-PD138039

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  • 1-Methyl-2'-O-methylinosine

    CAS :
    <p>1-Methyl-2'-O-methylinosine is a nucleoside that is naturally found in RNA. It is the methylated form of inosine, which is a nonessential amino acid and purine nucleotide. 1-Methyl-2'-O-methylinosine's chemical name is β--D--ribofuranosyl-(1'→2')--N--(6-fluoro-3-indoxyl)glycinamide monohydrochloride. This nucleoside has been researched for its potential use as an indexing tool for phylogenetic research of DNA and RNA. 1-Methyl-2'-O-methylinosine has also been shown to be structurally similar to other nucleic acids and has been classified as a nucleoside.</p>
    Formule :C12H16N4O5
    Degré de pureté :Min. 95%
    Masse moléculaire :296.28 g/mol

    Ref: 3D-NM159472

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  • Adenosine 5′-phosphosulfate triethylammonium salt


    <p>Adenosine 5′-phosphosulfate triethylammonium salt serves as a donor of sulfate groups in biochemical processes, such as in the synthesis of sulfate esters. The triethylammonium salt form improves the solubility and stability of the compound, making it useful in laboratory applications involving enzymatic assays and the synthesis of sulfated biomolecules.</p>
    Formule :C10H14N5O10PS·xC6H15N
    Degré de pureté :Min. 98.0 Area-%
    Couleur et forme :Powder
    Masse moléculaire :427.29 g/mol

    Ref: 3D-NA168321

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  • 9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine

    CAS :
    <p>9-(2'-Deoxy- 2'- fluoro- a- D- arabinofuranosyl) -9H- purin- 6- amine is an antiviral and anticancer agent. It can be used as a monophosphate or as a phosphoramidite for the synthesis of DNA, RNA, and modified nucleosides. The chemical name is 9-(2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine. It has the CAS number 20187-82-0. This drug was synthesized in 1976 by Koehler and colleagues at Bayer.<br>The molecular weight is 268.46 g/mol, with a melting point of 190°C, boiling point of 320°C and density of 1.408 g/mL at 20°C. It is soluble in water, methanol, ethanol, chloroform and acetic acid</p>
    Formule :C10H12FN5O3
    Degré de pureté :Min. 95%
    Couleur et forme :Solid
    Masse moléculaire :269.23 g/mol

    Ref: 3D-ND144479

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  • 5'-Azido-5'-deoxythymidine

    CAS :
    <p>5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.</p>
    Formule :C10H13N5O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :267.24 g/mol

    Ref: 3D-NA06452

    25mg
    224,00€
    50mg
    355,00€
    100mg
    501,00€
    250mg
    681,00€
    500mg
    804,00€
  • 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine

    CAS :
    <p>3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.<br>The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoyl</p>
    Formule :C16H16N6O4
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White Powder
    Masse moléculaire :356.34 g/mol

    Ref: 3D-NA08655

    10mg
    135,00€
    25mg
    184,00€
    50mg
    264,00€
    100mg
    400,00€
    250mg
    666,00€
  • N3-Methyl-2’-O-(2-methoxyethyl)uridine

    CAS :
    <p>N3-Methyl-2’-O-(2-methoxyethyl)uridine is a modified nucleoside that is synthesized from deoxyribonucleosides and ribonucleosides. It has antiviral, anticancer, and antifungal properties. N3-Methyl-2’-O-(2-methoxyethyl)uridine has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. This drug also inhibits the growth of human cancer cells in vitro and has been shown to be active against breast cancer cells. N3-Methyl-2’-O-(2-methoxyethyl)uridine is phosphorylated by cellular enzymes to form its active form, which binds to the viral reverse transcriptase enzyme and prevents DNA synthesis.</p>
    Formule :C13H20N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :316.31 g/mol

    Ref: 3D-NM163077

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  • 3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride


    <p>3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride is a novel nucleoside that inhibits the synthesis of viral DNA. It has antiviral activity against human herpes virus type 1 (HHV-1) and HIV, and is an anticancer agent. 3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride is synthesized by reacting a diaminopyrimidine with a 3',5'-dideoxyribonucleoside 5' phosphate in the presence of a coupling reagent such as HATU. This synthetic nucleoside has been shown to inhibit the replication of viruses, including human herpes virus type 1 (HHV-1), HIV, and Hepatitis C virus.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND168377

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  • 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt

    CAS :
    <p>Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.</p>
    Formule :C10H10BrN5O6P·Na
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :430.08 g/mol

    Ref: 3D-NB07971

    10mg
    135,00€
    25mg
    193,00€
    50mg
    280,00€
    100mg
    406,00€
    250mg
    744,00€
  • 3'-Deoxy-3'-fluoroadenosine

    CAS :
    <p>3'-Deoxy-3'-fluoroadenosine is a potent inhibitor of the phosphodiesterase enzyme, which is an important component of many different cellular processes. It has been shown to inhibit the activity of phosphodiesterase in cell culture and in serum alanine. 3'-Deoxy-3'-fluoroadenosine also inhibits the synthesis of uridine triphosphate, which is required for DNA replication and protein synthesis. The acid complex form has potent inhibition properties against viruses such as alphaviruses, and it also inhibits transport of nucleic acids into cells. 3'-Deoxy-3'-fluoroadenosine can act as an analog to adenosine and may be used to treat viral infections such as HIV or herpes simplex virus.</p>
    Formule :C10H12FN5O3
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :269.23 g/mol

    Ref: 3D-ND15616

    10mg
    231,00€
    25mg
    390,00€
    50mg
    540,00€
    100mg
    804,00€
    250mg
    1.206,00€
  • 3'-Deoxy-3'-fluoroguanosine

    CAS :
    <p>3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that is used for the treatment of viral hepatitis, cancer, and other diseases. 3'-Deoxy-3'-fluoroguanosine inhibits the replication of RNA by binding to the replicon. It binds to the RNA polymerase in a pharmacophore-based manner and inhibits its activity. When combined with other drugs, it has been shown to increase their efficacy. The combination of 3'-deoxy-3'-fluoroguanosine with interferon alpha 2b for the treatment of Hepatitis B has been shown to be more effective than either drug alone. The inhibition of cellular growth by 3'-deoxy-3'-fluoroguanosine may be due to its ability to inhibit rna synthesis.</p>
    Formule :C10H12N5O4F
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :285.23 g/mol

    Ref: 3D-ND10826

    1g
    1.791,00€
    50mg
    203,00€
    100mg
    333,00€
    250mg
    656,00€
    500mg
    1.023,00€
  • 2'-Deoxy-5'-O-pixylinosine


    <p>2'-Deoxy-5'-O-pixylinosine is a nucleoside that is structurally similar to the natural nucleosides. It is modified with an o-pixyl group at the 2' position of the sugar moiety and contains a phosphate group at the 5' position of the sugar moiety. 2'-Deoxy-5'-O-pixylinosine has antiviral, anticancer, and high purity properties due to its ability to inhibit viral DNA polymerases. This compound has been shown to be active against a broad spectrum of viruses including HIV and herpes simplex virus types 1 and 2 (HSV1 and HSV2). This compound is also able to inhibit tumor growth in vitro.</p>
    Formule :C30H26N4O4
    Degré de pureté :Min. 95%
    Masse moléculaire :506.57 g/mol

    Ref: 3D-ND08560

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  • 2'-O-(2-Methoxyethyl)-5-methylcytidine

    CAS :
    <p>2'-O-(2-methoxyethyl)-5-methylcytidine is a novel antiviral monophosphate nucleoside that has been shown to be a potent activator of the immune system. It was synthesized by modifying a deoxyribonucleoside and phosphoramidite. 2'-O-(2-methoxyethyl)-5-methylcytidine is synthetic and can be used as an anticancer drug for the treatment of leukemia, lymphoma, and other cancers. This compound has also shown efficacy in treating diphosphate nucleotides such as HIV-1 reverse transcriptase, which is an enzyme crucial for viral replication.</p>
    Formule :C13H21N3O6
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :315.32 g/mol

    Ref: 3D-NM36299

    1g
    488,00€
    2g
    650,00€
    5g
    911,00€
    10g
    1.072,00€
    500mg
    313,00€
  • (R)-N-(2,3-Dihydro-1H-indenyl)adenosine

    CAS :
    <p>(R)-N-(2,3-Dihydro-1H-indenyl)adenosine is a purine nucleoside with the attachment of a 2,3-dihydro-1H-indenyl group via a nitrogen atom. This adenosine-based product can be used for research purposes</p>
    Formule :C19H21N5O4
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :383.4 g/mol

    Ref: 3D-ND11705

    25mg
    194,00€
    50mg
    292,00€
    100mg
    364,00€
    250mg
    1.032,00€
    500mg
    1.376,00€
  • 3'-Amino-N4-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine


    <p>This product is a novel nucleoside analog with antiviral, anticancer and antiretroviral activities. It is an activator of ribonucleosides and deoxyribonucleosides. This product is synthesized by the phosphoramidite method. The purity of this product is greater than 98%.</p>
    Formule :C24H22N6O4
    Degré de pureté :Min. 95%
    Masse moléculaire :458.47 g/mol

    Ref: 3D-NA09002

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  • 2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine

    CAS :
    <p>2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine is an analog of the natural substrate for DNA cytosine methyltransferase, 5-methylcytosine. 2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine inhibits the enzyme activity of DNA methyltransferase and blocks cell proliferation. It has been shown to be a potent antitumor agent in experimental models and may serve as a potential biomarker for cancer treatment. The drug is an oral prodrug that is activated by deamination in the liver and kidneys to release the active form, 5'-Azacytidine monophosphate (5'AZA). This metabolite then inhibits DNA methylation by binding to DNA cytosine methyltransferase, resulting in a loss of function of this enzyme.</p>
    Formule :C10H12N4O4
    Degré de pureté :Min. 95%
    Masse moléculaire :252.23 g/mol

    Ref: 3D-NC29827

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  • 5-(Cyanomethyl)-uridine

    CAS :
    <p>5-(Cyanomethyl)-uridine (5-CMU) is a monophosphate nucleoside that is synthetically derived from uracil. This nucleoside has antiviral activity and can be used to treat infections caused by the herpesviridae family, such as herpes simplex virus type 1 and 2. 5-CMU is modified with cyanomethyl groups on the ribose moiety. It is also a phosphoramidite building block for DNA synthesis and can be used in the preparation of oligonucleotides. The CAS number for 5-CMU is 58479-73-5.</p>
    Formule :C11H13N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :283.24 g/mol

    Ref: 3D-NC159408

    1mg
    356,00€
    5mg
    1.201,00€
    10mg
    1.921,00€
  • 2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite


    <p>2'-Deoxy-5'-O-tritylinosine 3'-CE phosphoramidite is an anticancer drug that inhibits the growth of cancer cells. It is a modified nucleoside that is synthesized by reacting 2'-deoxy-5'-O-tritylinosine with a phosphoramidite. This product can be used for the synthesis of DNA, RNA and deoxyribonucleic acid (DNA).</p>
    Formule :C38H43N6O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :694.78 g/mol

    Ref: 3D-PD08649

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  • 3'-Deoxy-N-dimethylformamidine- 5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG


    <p>3'-Deoxy-N-dimethylformamidine-5'-O-DMT-guanosine-2'-O-succinoyl-long chain alkylamino-CPG is an anticancer, antiviral, and modified nucleoside. It is a novel monophosphate nucleoside that can be used in the synthesis of DNA or RNA. 3'-Deoxy-N-dimethylformamidine is a synthetic phosphoramidite that is activated with triethylamine and reacts with 5'--DMT--guanosine to yield a novel nucleoside. The compound has high purity and high quality.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND37120

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  • Coenzyme A sodium salt hydrate

    CAS :
    <p>Coenzyme A is a biochemical that is required for the synthesis of fat molecules. It also plays an important role in the activation of fatty acids, as well as in the production of collagen and growth factor-β1. Coenzyme A sodium salt hydrate (CAS) is a cofactor that participates in various metabolic processes, including process optimization and conjugation reactions. It has been shown to increase the transcription of insulin-sensitive genes, which may be due to its ability to inhibit the activity of nonsteroidal anti-inflammatory drugs. This product can be used in transfection experiments and fluorescence assays for cervical cancer or insulin sensitivity.</p>
    Formule :C21H36N7O16P3SNa
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :790.53 g/mol

    Ref: 3D-NC47123

    25mg
    298,00€
    50mg
    480,00€
    100mg
    874,00€
    250mg
    1.763,00€
    500mg
    2.639,00€
  • Adenine

    CAS :
    <p>Adenine is a nucleobase found in DNA and RNA. It is an essential component of the human body and is used in the production of phosphoramidites, which are chemical compounds that can be converted into phosphodiester bonds. Adenine has been shown to have anticancer properties, and it may function as a novel activator for other anticancer drugs. Adenine is also used as a monophosphate in some cases. The purity of this compound exceeds 99% and the molecular weight ranges from 162 to 166.5 Daltons.</p>
    Formule :C5H5N5
    Degré de pureté :Min. 98.0 Area-%
    Masse moléculaire :135.13 g/mol

    Ref: 3D-Z-1043

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  • 5-Methoxycarbonylmethyl-2-thiouridine

    CAS :
    <p>Nucleoside functionalised on the base</p>
    Formule :C12H16N2O7S
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :332.33 g/mol

    Ref: 3D-NM159492

    1mg
    349,00€
    2mg
    464,00€
    5mg
    875,00€
    10mg
    1.286,00€
    25mg
    2.047,00€
  • 4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D- ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

    CAS :
    <p>4-Chloro-7-(2C-methyl-3,5-bis-O-(4-methylbenzoyl)-b-D ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a monophosphate nucleotide analog. It is structurally related to the natural nucleoside 2′,3′ dideoxyadenosine. It can be used as an antiviral agent and has also been shown to have possible use in the treatment of HIV infections. 4C7DPP is a novel compound that is synthesized from phosphoramidites and activated with a novel activator. The purity of this compound is high and the quality is very good. CAS No. 1338072-45-9</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC163171

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  • 2'-Deoxy-N2-DMF-5'-O-tritylguanosine

    CAS :
    <p>2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a nucleoside that is used as a building block in the synthesis of oligonucleotides and other DNA analogues. It is a novel, synthetic nucleoside. The compound has antiviral and anticancer properties. It has been evaluated for use as an activator in antibody production and in the treatment of HIV infection and certain types of cancer. 2'-Deoxy-N2-DMF-5'-O-tritylguanosine is a phosphoramidite, which can be used to synthesize DNA or RNA. This product is available in high purity, diphosphate form and can be used to prepare Anticancer (CAS No. 40094-22-2) Novel Nucleosides (CAS No. 40094-22-2) Phosphoramidites (CAS No. 40094-22</p>
    Formule :C32H32N6O4
    Degré de pureté :Min. 95%
    Masse moléculaire :564.65 g/mol

    Ref: 3D-ND09133

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  • N6-Benzoyl-5'-O-DMT-adenosine

    CAS :
    <p>N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.</p>
    Formule :C38H35N5O7
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :673.73 g/mol

    Ref: 3D-NB07167

    2g
    224,00€
    5g
    356,00€
    10g
    509,00€
    25g
    1.005,00€
    50g
    1.667,00€
  • (E)-Ferulic acid 4-O-β-D-glucoside

    CAS :
    <p>(E)-Ferulic acid 4-O-β-D-glucoside is made up of ferulic acid, which is a natural compound found in things like rice, wheat and oats. Attached to this is a glucose molecule. This product can be used in research and potential be used to study its potential health benefits.</p>
    Formule :C16H20O9
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :356.32 g/mol

    Ref: 3D-NF180445

    1g
    1.213,00€
    50mg
    244,00€
    100mg
    382,00€
    250mg
    509,00€
    500mg
    804,00€
  • N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine


    <p>N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine is a nucleoside that is modified with a chlorine group. The modification of the nucleoside may enhance its anticancer activity. N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2 aminopurine has been shown to inhibit the growth of virus and cancer cells by inhibiting DNA synthesis. It has also been shown to induce apoptosis in human leukemia cells.</p>
    Formule :C21H30ClN5O9
    Degré de pureté :Min. 95%
    Couleur et forme :White to beige solid.
    Masse moléculaire :531.94 g/mol

    Ref: 3D-ND09536

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  • 2'-C-Methylguanosine

    CAS :
    <p>2'-C-Methylguanosine is a synthetic nucleoside analog of guanosine, modified at the 2'-carbon of the ribose sugar with a methyl group. This modification changes the molecule's biological behavior, making it potential useful in antiviral research and biochemical studies, especially those involving RNA synthesis.</p>
    Formule :C11H15N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :297.27 g/mol

    Ref: 3D-NM07819

    5g
    346,00€
    10g
    491,00€
    25g
    925,00€
    50g
    1.306,00€
    100g
    2.012,00€
  • 8-Benzyloxy-2'-deoxyguanosine

    CAS :
    <p>8-Benzyloxy-2'-deoxyguanosine is a dinucleoside that is synthesised from uracil and hydrogenated 8-hydroxyquinoline. The synthesis of 8-benzyloxy-2'-deoxyguanosine was achieved by cyclic photocyclization of 2,4,6-trichlorobenzaldehyde with 2,4,6-trimethoxyphenylacetone in the presence of sodium nitrite. This compound has been used for the quantification of DNA damage caused by irradiation or sodium chloride. 8-Benzyloxy-2'-deoxyguanosine has also been shown to inhibit the polymerase chain reaction (PCR) amplification of oligodeoxynucleotides.</p>
    Formule :C17H19N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White To Brown Solid
    Masse moléculaire :373.36 g/mol

    Ref: 3D-NB06296

    25mg
    297,00€
    100mg
    695,00€