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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 2-Chloro-N,N-dimethyl-2’C-methyladenosine

    CAS :
    <p>2-Chloro-N,N-dimethyl-2’C-methyladenosine is a synthetic nucleoside that inhibits viral DNA synthesis. It is a modified deoxyribonucleoside that contains a chloro group at the 2’ position of the sugar ring and a methyl group at the 3’ position. This drug has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2), respiratory syncytial virus (RSV), and influenza A virus. It also displays anticancer activity in vitro. This drug inhibits cancer cell growth by interfering with DNA replication and triggering apoptosis through inhibition of protein kinase C and activation of caspases.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC162856

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  • 3’C-Methylguanosine

    CAS :
    <p>3’C-Methylguanosine is a nucleoside that inhibits viral replication by acting as an antiviral agent. It is also used in anticancer treatments, and has been shown to be a novel phosphoramidite activator of DNA synthesis. 3’C-Methylguanosine has a CAS number of 115303-89-4, and the molecular weight is 277.3 g/mol. This chemical compound has not been modified or reacted with any other substances, and is suitable for use in research and development.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM163167

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  • 2,3,5-Tri-O-acetyl α-adenosine

    CAS :
    <p>2,3,5-Tri-O-acetyl α-adenosine is a nucleoside analog of adenosine that has been tri-acetylated. This molecule can be used in research.</p>
    Formule :C16H19N5O7
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :393.35 g/mol

    Ref: 3D-NT28569

    2mg
    323,00€
    5mg
    491,00€
    10mg
    845,00€
    25mg
    1.449,00€
    50mg
    2.565,00€
  • Cytidine-2'-monophosphate sodium

    CAS :
    <p>Cytidine-2'-monophosphate sodium (CMP) is a nucleotide that is used as a monophosphate or diphosphate. It can be used to synthesize DNA and RNA. CMP also has antiviral, anticancer, and high purity properties. CMP is an activator of DNA polymerases and helps in the synthesis of DNA. It has novel properties that make it different from other nucleotides, such as its modified sugar moiety.</p>
    Formule :C9H12Na2N3O8P
    Degré de pureté :Min. 90%
    Couleur et forme :Powder
    Masse moléculaire :367.18 g/mol

    Ref: 3D-NC13474

    25g
    340,00€
    50g
    504,00€
    100g
    795,00€
  • 2'-O-Propargylcytidine

    CAS :
    <p>2'-O-Propargylcytidine is a novel nucleoside that has been modified from cytidine. It is designed to inhibit the activity of RNA polymerase and to be used in anticancer therapy. The synthesis of 2'-O-propargylcytidine has been achieved by modifying the nucleotide with propargylic chloride, which is then reacted with sodium cyanide. The resulting product is purified by column chromatography and recrystallization.<br>2'-O-Propargylcytidine is a phosphoramidite that can be used for DNA synthesis or as a monophosphate in RNA synthesis. This high purity product has a CAS number of 206552-85-4 and it can be used as an activator for ribonucleosides, such as adenosine, guanosine, uridine, cytidine, and thymidine.</p>
    Formule :C12H15N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :281.26 g/mol

    Ref: 3D-NP06202

    10mg
    189,00€
    25mg
    401,00€
    50mg
    679,00€
    100mg
    1.289,00€
  • 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine

    CAS :
    <p>6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is a modified monophosphate analog of adenosine. It is an antiviral agent that inhibits the synthesis of nucleic acids in virus-infected cells, preventing viral replication and spread. 6-(4-Morpholino)-9-(β-D-ribofuranosyl)-9H-purine is also used as a radiosensitizer to treat cancer. This drug is synthesized by high purity, high quality and reliable suppliers.</p>
    Formule :C14H19N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :337.33 g/mol

    Ref: 3D-NM163017

    25mg
    382,00€
    50mg
    595,00€
    100mg
    965,00€
  • 2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine


    <p>2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analogue with antiviral and anticancer properties. It is an activator of ribonucleotide reductase and inhibits DNA synthesis by inhibiting deoxyribonucleotide reductase. 2,3'-Anhydro-5'-O-p-anisoyl-N4-benzoyl-2'-deoxycytidine has shown to be a potent inhibitor of HIV replication in vitro. It also has anticancer activity by inhibiting the growth of tumor cells and inducing apoptosis.</p>
    Formule :C24H23N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :449.46 g/mol

    Ref: 3D-NA09230

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  • 5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine

    CAS :
    <p>5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine is a novel antiviral drug that inhibits the synthesis of viral DNA. It has been shown to be effective against HIV, herpes simplex virus and cytomegalovirus (CMV). 5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine is a nucleoside analogue that can be used as an activating agent in the synthesis of oligonucleotides and phosphoramidites. It has anticancer properties and may also have applications in gene therapy.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM162859

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  • 6-Amino-3-iodo-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS :
    <p>6-Amino-3-iodo-4-methoxy-1-(beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and can be used to synthesize DNA and RNA. 6AIOMP binds to the ribonucleotide reductases in cells and inhibits their activity. This prevents the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162944

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  • 3-Deaza-2'-O-methyluridine

    CAS :
    <p>3-Deaza-2'-O-methyluridine is a nucleoside that is used as an antiviral agent and in the treatment of leukemia. It has been shown to inhibit the growth of L1210 cells in a dose-dependent manner. 3-Deaza-2'-O-methyluridine also inhibits the synthesis of DNA, RNA, and proteins. The compound is eliminated by renal excretion with a plasma elimination half life of 9 hours. This drug can be administered intramuscularly or intravenously at a dosage of 10 mg/kg every 8 hours, but should not be given more than 5 days without interruption due to accumulation in tissues.</p>
    Formule :C11H15NO6
    Degré de pureté :Min. 95%
    Masse moléculaire :257.24 g/mol

    Ref: 3D-ND58308

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  • 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine

    CAS :
    <p>5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.</p>
    Formule :C11H11N2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :251.22 g/mol

    Ref: 3D-NA144872

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  • 5’-O-DMT-2’-b-C-methyladenosine


    <p>5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND163091

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  • 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine

    CAS :
    <p>3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is a novel synthetic nucleoside that has been shown to have anticancer and antiviral activities. The compound is an activator of the immune system, which may be due to its ability to stimulate the production of interferon and other cytokines. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine can also inhibit viral DNA polymerases. This nucleoside has been shown to inhibit the growth of leukemia cells in culture by inhibiting ribonucleotide reductase activity.</p>
    Formule :C16H29N3O5Si
    Degré de pureté :Min. 95%
    Masse moléculaire :371.51 g/mol

    Ref: 3D-NA09004

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  • 5'-Azido-5'-deoxyadenosine

    CAS :
    <p>5'-Azido-5'-deoxyadenosine (Aza-dA) is an adenosine analog that inhibits the deamination of S-adenosylhomocysteine to form adenosine. It has been shown to be more potent than 2-chloroadenosine and inactivates the enzyme s-adenosylhomocysteine hydrolase, which is responsible for the conversion of S-adenosylhomocysteine to adenosine. This leads to decreased levels of adenosine and increased levels of s-adensoylhomocysteine. Aza-dA has been shown to inhibit tumor growth and induce apoptosis in rat hepatocytes. In addition, it is a halogenated molecule that can be used as a modifying agent.</p>
    Formule :C10H12N8O3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :292.25 g/mol

    Ref: 3D-NA46264

    1g
    5.102,00€
    100mg
    876,00€
    250mg
    1.723,00€
    500mg
    2.821,00€
  • 3’-deoxy-3’-fluorosangivamycin

    CAS :
    <p>3’-deoxy-3’-fluorosangivamycin is a modified deoxyribonucleoside with antiviral and anticancer properties. It is an activator of DNA polymerase. 3’-deoxy-3’-fluorosangivamycin has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in the calf thymus DNA system. This drug is also effective against other viruses, such as herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and influenza A virus. 3′-deoxy-3′-fluorosangivamycin binds to viral DNA and inhibits nucleotide incorporation, leading to inhibition of viral RNA synthesis and protein synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-MD162938

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  • 2'-Deoxy-N6-(2-hydroxyethyl)adenosine

    CAS :
    <p>2'-Deoxy-N6-(2-hydroxyethyl)adenosine is a synthetic nucleoside that is used as a building block for the chemical synthesis of oligonucleotides. It is also an antiviral agent and has been shown to have anticancer properties. 2'-Deoxy-N6-(2-hydroxyethyl)adenosine is used in the manufacture of phosphoramidites, deoxyribonucleosides, and ribonucleosides. This product can be synthesized at high purity and quality, with CAS No. 137058-94-7.</p>
    Formule :C12H17N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :295.29 g/mol

    Ref: 3D-ND16751

    5mg
    222,00€
    10mg
    333,00€
    25mg
    617,00€
    50mg
    936,00€
    100mg
    1.310,00€
  • 6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a novel synthetic ribonucleotide that inhibits the growth of tumor cells by interfering with DNA synthesis. This compound has been shown to inhibit the replication of HIV and herpes simplex virus type 1. The phosphoramidite monomer is readily available and can be synthesized in high purity and high quality. 6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is activated by phosphorylation at the 5' position. CAS No.: 10266890</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162982

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  • 2’-O-Acetyl-8-bromo-7-cyano-7-deaza-3’-deoxy-3’-fluoro-5’-O-toluoyladenosine


    <p>2'-O-Acetyl-8-bromo-7-cyano-7-deaza-3'-deoxy-3'-fluoro-5'-O-[toluoyl]adenosine (ABT) is a modified nucleoside that has anticancer and antiviral properties. ABT is a monophosphate nucleotide with an acetyl group at the 2' position of the ribose and a toluoyl group on the 7 position of the adenine moiety. In vitro, ABT inhibits tumor proliferation in breast cancer cells and suppresses viral replication in herpes simplex virus type 1 (HSV1) infected cells. ABT also has potential as a novel therapeutic agent for treating cancers and other diseases caused by HSV1 infection.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162935

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  • 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine

    CAS :
    <p>Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FD144638

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  • 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine

    CAS :
    <p>4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine is a monophosphate of the nucleoside 5FU. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by competitively inhibiting the activity of thymidylate synthase, which converts dUMP to dTMP. 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine also induces apoptosis in neoplastic cells. This compound has high purity and quality, and can be used as a phosphoramidite for the synthesis of modified oligonucleotides.</p>
    Formule :C10H10FNO4
    Degré de pureté :Min. 95%
    Masse moléculaire :227.19 g/mol

    Ref: 3D-ND138640

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  • Pseudothymidine

    CAS :
    <p>Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.</p>
    Formule :C10H14N2O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :242.23 g/mol

    Ref: 3D-NP16241

    5mg
    274,00€
    10mg
    430,00€
    25mg
    765,00€
    50mg
    1.288,00€
    100mg
    1.932,00€
  • N6-Benzoyl-2'-C-methyladenosine


    <p>N6-Benzoyl-2'-C-methyladenosine is synthetic and has antiviral properties. It is a nucleoside that belongs to the group of modified nucleosides. This compound can be used as an activator for DNA synthesis and as a novel monophosphate, diphosphate, or triphosphate. N6-Benzoyl-2'-C-methyladenosine is also available in high purity, with CAS No., and at a competitive price.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB137591

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  • 2,3'-Anhydrouridine 5'-CE phosphoramidite


    <p>2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.</p>
    Formule :C18H27N4O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :426.41 g/mol

    Ref: 3D-PA09084

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  • 8-Azido-2'-deoxyadenosine

    CAS :
    <p>8-azido-2-deoxyadenosine is an azide funcationalised nuceleoside</p>
    Formule :C10H12N8O3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :292.25 g/mol

    Ref: 3D-NA44903

    10mg
    334,00€
    25mg
    551,00€
    50mg
    835,00€
  • 3'-O-Aminoacetoxy-2'-deoxycytidine


    <p>Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C12H18N4O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :282.30 g/mol

    Ref: 3D-NA180285

    1g
    1.408,00€
    100mg
    262,00€
    500mg
    923,00€
  • b-L-2',3'-Dideoxy-5-fluorocytidine

    CAS :
    <p>b-L-2',3'-Dideoxy-5-fluorocytidine is a pyrimidine nucleoside that inhibits the deoxycytidine kinase enzyme, which catalyzes conversion of deoxycytidine to cytidine. It has potent inhibition against human lymphocytes and liver cells, as well as virus replication. b-L-2',3'-Dideoxy-5-fluorocytidine has potent antitumor activity in vitro and in vivo, with an inhibitory effect on immunodeficiency and hepatitis. This drug also has a potent inhibitory effect on T-cell growth in cell culture. b-L-2',3'-Dideoxy-5-fluorocytidine is converted to 5'-deoxyfloxuridine by cellular enzymes and then to 5'-deoxyuridylate by the enzyme uridylate kinase. The latter compound inhibits DNA synthesis by inhibiting thymidyl</p>
    Formule :C9H12FN3O3
    Degré de pureté :Min. 95%
    Masse moléculaire :229.21 g/mol

    Ref: 3D-ND157001

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  • 5'-Amino-5'-deoxythymidine

    CAS :
    <p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>
    Formule :C10H15N3O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :241.24 g/mol

    Ref: 3D-NA06395

    1g
    1.515,00€
    50mg
    254,00€
    100mg
    400,00€
    250mg
    723,00€
    500mg
    1.047,00€
  • 1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine

    CAS :
    <p>1-(2'-Deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-4-amino-1,2-dihydro-2-oxo-1,3,5-triazine is a nucleoside derivative that features a modified pyrimidinone (triazine) base attached to a protected deoxyribose sugar. This molecule can be used in research.</p>
    Formule :C24H24N4O6
    Degré de pureté :Min. 95%
    Couleur et forme :White To Off-White Solid
    Masse moléculaire :464.48 g/mol

    Ref: 3D-ND04704

    10mg
    140,00€
  • 3’-β-Azido-2’,3’-dideoxy-5-fluorouridine

    CAS :
    <p>Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FA144641

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  • CTP 2Na

    CAS :
    <p>CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.</p>
    Formule :C9H14N3Na2O14P3
    Degré de pureté :Min. 95.0 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :527.12 g/mol

    Ref: 3D-NC03860

    5g
    247,00€
    50g
    772,00€
  • 5'-O-Tritylthymidine

    CAS :
    <p>5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.</p>
    Formule :C29H28N2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :484.54 g/mol

    Ref: 3D-NT08062

    1g
    215,00€
    2g
    349,00€
    5g
    538,00€
    250mg
    134,00€
    500mg
    150,00€
  • 1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol


    <p>1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is a novel, activator ribonucleosides deoxyribonucleosides diphosphate phosphoramidites modified anticancer antiviral monophosphate nucleosides synthetic high purity CAS No. It has been shown to have anticancer and antiviral properties. This compound also inhibits the replication of HIV in vitro.</p>
    Formule :C15H21N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :351.37 g/mol

    Ref: 3D-NA07924

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  • 2'-Deoxyuridine-5'-triphosphate trisodium

    CAS :
    <p>2'-Deoxyuridine-5'-triphosphate trisodium salt is a fluorophore that is excited by the absorption of light at wavelengths of 365 nm. The emission spectrum ranges from 380 to 500 nm and has a maximum at 480 nm. 2'-Deoxyuridine-5'-triphosphate trisodium salt can be used as a labeling agent for metal ion, molecule, or macrocyclic ligand. It can also be used as an acceptor in fluorescence energy transfer experiments.</p>
    Formule :C9H15N2O14P3•Na3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :537.11 g/mol

    Ref: 3D-ND08736

    1g
    1.179,00€
    50mg
    239,00€
    100mg
    400,00€
    250mg
    746,00€
    500mg
    882,00€
  • Clofarabine 5'-triphosphate triethylammonium salt

    CAS :
    <p>Clofarabine is a nucleoside analog that is used to treat various types of cancer, including leukemia, lymphoma, and solid tumours. Clofarabine has been shown to have minimal toxicity in healthy cells and is usually well tolerated by patients. It acts by inhibiting the synthesis of DNA in rapidly dividing cells. This effect can be synergistic with other anti-cancer agents such as the cytotoxic agent Bleomycin. Clofarabine binds to an intracellular target and inhibits DNA synthesis by blocking the enzyme DNA polymerase. Inhibition of this enzyme leads to cell death. Clofarabine has been tested in pediatric patients from age 1 month old up to 18 years old. The drug has been found to be safe for use in this population.</p>
    Formule :C10H14ClFN5O12P3
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :543.62 g/mol

    Ref: 3D-NC15333

    1mg
    615,00€
    2mg
    1.028,00€
    5mg
    1.964,00€
    10mg
    3.360,00€
    25mg
    6.714,00€
  • 2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine 3'-CE-phosphoramidite


    <p>2'-Deoxy-5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine 3'-CE-phosphoramidite is a novel nucleoside analog with anticancer and antiviral activity. It is a cytidine derivative that contains a fluorine atom at the 2' position of the ribose ring, which leads to reduced immunogenicity. The deoxyribonucleoside analogs are synthesized by chemical phosphorylation of 5'-O-DMT-2'-fluoro-N4-phenoxyacetylcytidine 3'-phosphoramidite in high purity and high quality as well as in small quantities.</p>
    Formule :C47H55N5O9FP
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Off-White Yellow Powder
    Masse moléculaire :883.94 g/mol

    Ref: 3D-PD158882

    1g
    376,00€
    2g
    502,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    258,00€
  • 2-Amino-6-chloro-9-(2’-O-propargyl-b-D-ribofuranosyl)purine

    CAS :
    <p>2-Amino-6-chloro-9-(2'O-propargyl-bDribofuranosyl)purine is a modified nucleoside that has antiviral and anticancer properties. It has been shown to inhibit DNA synthesis in the presence of deoxyribonucleosides, diphosphate, and Nucleosides. The compound was also found to inhibit the replication of herpes simplex virus type 1 (HSV-1) by interfering with viral DNA polymerase and causing chain termination. 2-Amino-6-chloro-9-(2'O-propargyl-bDribofuranosyl)purine is a novel compound that can be used as a high quality pharmaceutical ingredient for cancer treatments.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162911

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  • 3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine

    CAS :
    <p>3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine is a modified nucleoside that can be used as an antiviral agent. It is a phosphoramidite that is activated by diphosphate and has been shown to inhibit DNA replication in vitro. 3'-O-Acetyl-2'-deoxy-N2-isobutyrylguanosine also has anticancer activity and can be used to treat leukemia, lymphoma, and myeloma. This high quality product is synthesized from natural deoxyribonucleosides and has a purity of &gt; 98%.</p>
    Formule :C16H21N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :379.37 g/mol

    Ref: 3D-NA76379

    50mg
    135,00€
    100mg
    179,00€
    250mg
    304,00€
    500mg
    477,00€
  • 2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine


    <p>2'-Deoxy-5-(2-hydroxyethyl)-2',3'-di-O-toluoyluridine is a novel modified nucleoside with antiviral and anticancer activities. It is synthesized from 2'-deoxyuridine monophosphate, which is activated with bis(trimethylsilyl)acetamide (BSA). This nucleoside has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-MD163177

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  • 3'-O-Aminoacetoxythymidine


    <p>Amino functionalised thymidine</p>
    Formule :C13H21N4O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :297.33 g/mol

    Ref: 3D-NA180283

    1g
    1.355,00€
    100mg
    262,00€
    500mg
    860,00€
  • 5’-O-Benzoyl-3’-O-(4-methoxybenzoyl)-2’-O,4’-C- methyleneuridine


    <p>5'-O-Benzoyl-3'-O-(4-methoxybenzoyl)-2'-O,4'-C-methyleneuridine is a nucleoside that is synthesized from 5'-O-benzoyl-2'-deoxyadenosine and 4'-methoxybenzoyl chloride. It has antiviral and anticancer properties. 5' - O - benzoyl - 3' - O - (4-methoxybenzoyl) - 2' - O,4' - C methyleneuridine is a novel nucleoside with anti-cancer and antiviral effects. It can also be used as an activator for the synthesis of oligonucleotides or as a ribonucleotide phosphoramidite. The chemical name for this compound is 5’ – O – benzoyl – 3’ – O – (4 methoxybenzoyl) – 2</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB163149

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  • 3'-O-Aminoacetoxy-2'-deoxyguanosine


    <p>Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C13H17N6O4
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :321.32 g/mol

    Ref: 3D-NA180286

    1g
    1.408,00€
    100mg
    262,00€
    500mg
    923,00€
  • 6-Amino-2-(2',3',5'-tri-O-benzoyl-b-D-ribofuranosyl)-4-methoxy-2H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-2-(2',3',5'-tri-O-benzoyl-b-D-ribofuranosyl)-4-methoxy-2H-pyrazolo[3,4-d]pyrimidine (6APB) is a synthetic nucleoside that is an antiviral agent. It inhibits the viral enzyme DNA polymerase, which prevents synthesis of viral DNA. 6APB has been shown to be active against herpes simplex virus type 1 and 2, influenza A virus and cytomegalovirus. The compound also has a novel structure with an amino group at the 3'-position of the sugar moiety. This modification allows for selective incorporation of 6APB into oligonucleotides during chemical synthesis, which eliminates the need for purification steps following nucleotide addition. 6APB is also high purity, with a CAS number of 104057-61-8.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA162977

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  • 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine

    CAS :
    <p>1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).</p>
    Formule :C9H12ClN3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :261.66 g/mol

    Ref: 3D-NC29834

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  • 6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine


    <p>6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine is a novel antiviral and anticancer agent that belongs to the class of nucleosides. It is a monophosphate and diphosphate analog of deoxyinosine, which has been modified with a 2-(4-nitrophenyl)ethyl group at the 6 position. This modification prevents phosphorylation by kinases, which inhibits DNA synthesis. The nitro group in 6-O-[2-(4-Nitrophenyl)ethyl]-2-[(3-pyridyl)pyrrolidin-1- yl]-2’-deoxyinosine provides an additional mechanism for inhibiting DNA synthesis by interacting with the DNA minor groove and preventing the binding of DNA polymerase. In addition, this compound has antic</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FN162927

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  • 3’-b-C-Methylcytidine

    CAS :
    <p>3’-b-C-Methylcytidine is a nucleoside analog that inhibits the viral enzyme reverse transcriptase and is used as an antiviral agent. 3’-b-C-Methylcytidine binds to DNA and prevents RNA synthesis, which is essential for viral replication. It has been shown to inhibit the growth of cultured cells from human breast cancer and melanoma, suggesting that it also has anticancer activity. 3’-b-C-Methylcytidine can be synthesized in high purity and at high yield using phosphoramidites. This nucleoside analog may be useful in clinical applications due to its ability to activate transcription, which may lead to novel therapeutic strategies.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-MM163085

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  • 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil

    CAS :
    <p>2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a novel and high purity anticancer and antiviral agent. It is an activator that has been shown to exhibit antineoplastic activity in vitro. The compound also inhibits the formation of RNA and DNA, which are necessary for the replication of cells. 2,2'-Anhydro-6-methoxycarbonyl-b-D-arabinofuranosyl uracil is a modified nucleoside that has been synthesized by phosphoramidite chemistry. This product can be used for research purposes and as a starting material for the synthesis of other compounds with similar structures.</p>
    Formule :C11H12N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :284.22 g/mol

    Ref: 3D-NA00714

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  • 5'-Azido-2',5'-dideoxy-2'-fluorouridine

    CAS :
    <p>5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.</p>
    Formule :C9H10FN5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :271.21 g/mol

    Ref: 3D-NA163005

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  • b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium)

    CAS :
    <p>b-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium), or NADPH, is involved in redox reactions, where it acts as an electron donor. NADPH is essential for anabolic reactions, such as lipid and cholesterol biosynthesis, and fatty acid chain elongation. It also plays a significant role in antioxidation mechanisms, protecting cells from oxidative stress by neutralizing reactive oxygen species (ROS) and regenerating antioxidants like glutathione</p>
    Formule :C21H30N7O17P3·4C6H13N
    Degré de pureté :Min. 90 Area-%
    Couleur et forme :Slightly Yellow Powder
    Masse moléculaire :1,142.12 g/mol

    Ref: 3D-FN46723

    1g
    547,00€
    2g
    806,00€
    5g
    1.518,00€
    250mg
    291,00€
    500mg
    410,00€
  • 2-Chloro-2',3'-O-isopropylideneadenosine

    CAS :
    <p>2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.</p>
    Formule :C13H16ClN5O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :341.75 g/mol

    Ref: 3D-NC06329

    1g
    1.440,00€
    50mg
    222,00€
    100mg
    328,00€
    250mg
    526,00€
    500mg
    957,00€
  • 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine

    Produit contrôlé

    <p>3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine is a novel modified nucleoside that has antiviral and anticancer properties. It is an activator of the DNA polymerase, ribonucleotide reductase, and thymidine kinase enzymes. 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine has been shown to inhibit the growth of human cancer cells in vitro and in vivo.</p>
    Formule :C18H18N3O7D3
    Degré de pureté :Min. 95%
    Masse moléculaire :394.39 g/mol

    Ref: 3D-NA09001

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