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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 3'-Azido-2',3'-dideoxyuridine

    CAS :
    <p>3'-Azido-2',3'-dideoxyuridine is an analog of the nucleoside dideoxyuridine that inhibits HIV replication. It has a high inhibitory dose and low toxicity. 3'-Azido-2',3'-dideoxyuridine is converted to its active form, 3'-azido-2',3'-dideoxythymidine (AZT), by dephosphorylation in human serum. AZT inhibits HIV replication by competing with the natural substrate for viral DNA polymerase, thereby inhibiting synthesis of viral DNA. 3'-Azido-2',3'-dideoxyuridine has been shown to be effective against hepatitis B virus and hepatitis C virus in cell cultures.</p>
    Formule :C9H11N5O4
    Degré de pureté :Min. 95%
    Couleur et forme :Off-White Powder
    Masse moléculaire :253.21 g/mol

    Ref: 3D-NA05737

    10mg
    303,00€
    25mg
    473,00€
    50mg
    666,00€
    100mg
    1.002,00€
    250mg
    1.566,00€
  • 4-Amino-2-chloro-5-fluoropyrimidine

    CAS :
    <p>4-Amino-2-chloro-5-fluoropyrimidine is a chlorinating agent that is used in the synthesis of 4,5-dichloropyrimidine and 4,6-dichloropyrimidine. It is also used for the synthesis of oxychloride by reacting with phosphorus oxychloride or phosphorus.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA44305

    1g
    403,00€
    500mg
    300,00€
  • 8-Bromo-2'-O-methyladenosine


    <p>8-Bromo-2'-O-methyladenosine is a modified nucleoside that is used as an antiviral and anticancer drug. It is also a high quality, novel, phosphoramidite building block. 8-Bromo-2'-O-methyladenosine has been shown to inhibit the growth of human cancer cells in culture and has anti-inflammatory effects in mice.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB145743

    100mg
    303,00€
    250mg
    457,00€
    500mg
    764,00€
  • 5'-Azido-2',5'-dideoxyinosine

    CAS :
    <p>5'-Azido-2',5'-dideoxyinosine is a novel nucleoside which has been synthesized to investigate its anticancer and antiviral properties. 5'-Azido-2',5'-dideoxyinosine is an activator of ribonucleosides and deoxyribonucleosides, converting them into the corresponding monophosphate or diphosphate form. This product can be used as a building block for the synthesis of phosphoramidites and modified nucleosides. 5'-Azido-2',5'-dideoxyinosine has shown activity against cancer cells in vitro, in particular leukemia cell lines. It also has antiviral activity against HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV).</p>
    Formule :C10H11N7O3
    Degré de pureté :Min. 95%
    Masse moléculaire :277.24 g/mol

    Ref: 3D-NA45439

    5mg
    303,00€
    10mg
    319,00€
    25mg
    491,00€
  • 4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite

    CAS :
    <p>4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a novel DNA synthesis inhibitor that is synthesized by the reaction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine and phosphorous oxychloride. This product has antiviral and anticancer activities, as well as high purity and high quality. It can be used in cellular biology research, including the study of ribonucleosides, nucleosides, and deoxyribonucleosides. This product also inhibits HIV replication in vitro.</p>
    Formule :C42H50N5O7PS
    Degré de pureté :Min. 95%
    Masse moléculaire :799.93 g/mol

    Ref: 3D-PC08807

    250mg
    1.091,00€
  • 5,6-Diaminouracil

    CAS :
    <p>5,6-Diaminouracil is a nitrogen-containing heterocyclic compound that inhibits bacterial enzymes. 5,6-Diaminouracil is used as a pharmaceutical preparation for the treatment of cancer, and has been shown to be effective against various cancers, including colon cancer and breast cancer. 5,6-Diaminouracil can inhibit the growth of cells by binding to DNA and inhibiting DNA synthesis. This drug also has potent antitumor activity. 5,6-Diaminouracil has been used in analytical chemistry as an analytical method for determining the purity of products such as pharmaceuticals or dyes. The potency of this drug was determined electrochemically using cyclic voltammetry and it was found to have a constant inhibitory effect on tumor cell growth at low concentrations.</p>
    Formule :C4H7ClN4O2
    Degré de pureté :Min. 95%
    Masse moléculaire :178.58 g/mol

    Ref: 3D-ND66272

    1g
    300,00€
    2g
    376,00€
    5g
    538,00€
  • Cytarabine-5-monophosphate-15N2,13C1


    <p>Cytarabine-5-monophosphate-15N2, 13C1 is a monophosphate nucleoside that inhibits viral replication. It is an antiviral agent used in the treatment of herpes simplex virus infections and other viruses such as HIV. Cytarabine-5-monophosphate-15N2, 13C1 also has anticancer properties and can be used to prevent cancer by inhibiting DNA synthesis. The compound is a modified nucleoside that lacks the 2' hydroxyl group and has an activated phosphate at the 3' position. This novel nucleoside is synthesized from deoxyribonucleosides using phosphoramidites as starting materials. CAS No.: 127468-52-8</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC11680

    1g
    2.440,00€
  • N6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution

    CAS :
    <p>Modulator of P2Y receptors</p>
    Formule :C11H18N5O13P3
    Degré de pureté :Min. 95%
    Masse moléculaire :521.21 g/mol

    Ref: 3D-NM71656

    5mg
    1.223,00€
    10mg
    2.033,00€
    2500µg
    728,00€
  • 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt


    <p>Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C13H22N3O14P3•(C6H15N)x
    Degré de pureté :Min. 99 Area-%
    Couleur et forme :Powder
    Masse moléculaire :537.25 g/mol

    Ref: 3D-NA180287

    5mg
    À demander
  • O6-Phenyl-2'-deoxyinosine

    CAS :
    <p>O6-Phenyl-2'-deoxyinosine is a high purity, modified nucleoside that is a novel anticancer agent. It is used as a phosphoramidite in the synthesis of DNA and RNA. It has been shown to have cytotoxic effects against tumor cells and enhances the efficacy of chemotherapy. O6-Phenyl-2'-deoxyinosine has also been shown to be an activator of transcription factors, including NF-κB, AP-1, and STAT3.</p>
    Formule :C16H16N4O4
    Degré de pureté :Min. 95%
    Masse moléculaire :328.32 g/mol

    Ref: 3D-PEA48536

    250mg
    639,00€
    500mg
    974,00€
  • N6-Benzoyl-2',3'-dideoxyadenosine

    CAS :
    <p>N6-Benzoyl-2',3'-dideoxyadenosine is a nucleoside analog that inhibits the growth of Mycobacterium tuberculosis by preventing DNA replication. It is also a potent inhibitor of DNA synthesis, and binds to the beta-subunit of bacterial RNA polymerase, leading to inhibition of transcription. N6-Benzoyl-2',3'-dideoxyadenosine has shown in vitro activity against Mycobacterium tuberculosis and other bacteria that have been found to be resistant to conventional antibiotics.</p>
    Formule :C17H17N5O3
    Degré de pureté :Min. 95%
    Couleur et forme :White/Off-White Solid
    Masse moléculaire :339.36 g/mol

    Ref: 3D-NB08369

    10mg
    135,00€
    25mg
    210,00€
    50mg
    353,00€
    100mg
    553,00€
    250mg
    1.044,00€
  • 3'-epi-5-chloro-2'-deoxyuridine

    CAS :
    <p>3'-epi-5-chloro-2'-deoxyuridine is a nucleotide analog that has been shown to inhibit the growth of cells in tissue culture. It is not active against bacteria, but can be used as an antineoplastic agent for the treatment of cancer. 3'-epi-5-chloro-2'-deoxyuridine is metabolized by a number of enzymes, including mononucleotide reductase, thymidylate synthase, and cytosine deaminase. The reaction mechanism for this drug has been studied using nuclear dna polymerases and proteases. The metabolism of 3'-epi-5-chloro-2'-deoxyuridine results in its incorporation into DNA by means of an enzymatic reaction with DNA polymerase. The incorporation of the analog into DNA leads to cell death due to lysis or inhibition of protein synthesis.</p>
    Formule :C9H11ClN2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :262.65 g/mol

    Ref: 3D-NE16712

    2mg
    303,00€
    5mg
    501,00€
    10mg
    769,00€
    25mg
    1.318,00€
    50mg
    2.331,00€
  • 2'-Deoxy-5-fluoroadenosine


    <p>2'-Deoxy-5-fluoroadenosine is a nucleoside that is used in the synthesis of DNA and RNA. It has antiviral activity and can be used as an anticancer agent. This nucleoside is synthesized by reacting 2'-deoxyadenosine with 5-fluorouracil in a high-quality, high purity environment under stringent conditions. 2'-Deoxy-5-fluoroadenosine has also been shown to have antiretroviral activity against HIV and hepatitis B virus.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND02602

    1g
    2.440,00€
  • 4-Phenylpyrimidine-2-thiol

    CAS :
    <p>4-Phenylpyrimidine-2-thiol is a chemical compound that belongs to the group of elemental compounds. It has a density of 1.5 g/mL, a melting point of &gt; 200 °C, and a boiling point of &gt; 300 °C. 4-Phenylpyrimidine-2-thiol has been shown to exist as chains with assembled chains in the crystalline state. The crystals are composed of two molecules stacked on top of each other in an antiparallel orientation. The crystal structure was solved through x-ray crystallography and single-crystal x-ray diffraction. 4-Phenylpyrimidine-2-thiol is dimeric in solution and polymerizes in the solid state to form polymers with chains consisting of four phenylpyrimidine units. This compound has an elemental analysis consisting mainly of carbon and hydrogen, with small amounts of sulfur and nitrogen present.</p>
    Formule :C10H8N2S
    Degré de pureté :Min. 95%
    Masse moléculaire :188.25 g/mol

    Ref: 3D-NP57408

    1g
    300,00€
    2g
    376,00€
    5g
    538,00€
    10g
    793,00€
  • 5-Aminoallyl-2'-deoxyuridine

    CAS :
    <p>5-Aminoallyl-2'-deoxyuridine is a bifunctional alkylating agent that has low affinity for DNA. It is used in the laboratory to measure the rate of synthesis of thymidylate, which is one of the four deoxythymidylate needed for DNA synthesis. 5-Aminoallyl-2'-deoxyuridine has been shown to be a stable complex with sulfoxide, which can be used as an alkylation agent in the laboratory. 5-Aminoallyl-2'-deoxyuridine has also been shown to have high affinity for cellular nucleic acids in l1210 cells and have a high uptake. The sequence of 5-aminoallyl-2'-deoxyuridine is: 5-(N-(2-(5-aminoallylamino)ethyl)-N-(carboxyethyl)glycine)-2',3',5'-triiod</p>
    Formule :C12H18N4O4
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :282.3 g/mol

    Ref: 3D-NA02924

    10mg
    481,00€
    25mg
    847,00€
    50mg
    1.221,00€
    100mg
    1.941,00€
    250mg
    3.203,00€
  • 2-Thio-2'-deoxycytidine

    CAS :
    <p>2-Thio-2'-deoxycytidine is a polycrystalline material that belongs to the group of experimental materials. 2-Thio-2'-deoxycytidine is a tautomeric form of cytosine which has been studied theoretically and experimentally. It has been shown that this compound is stable in the environment and can be used as a research material.</p>
    Formule :C9H13N3O3S
    Degré de pureté :Min. 95%
    Masse moléculaire :243.29 g/mol

    Ref: 3D-UGA55713

    50mg
    954,00€
    100mg
    1.251,00€
  • 2',3',5'-Tri-O-benzoyl-2-thiouridine

    CAS :
    <p>2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).</p>
    Formule :C30H24N2O8S
    Degré de pureté :Min. 95%
    Masse moléculaire :572.59 g/mol

    Ref: 3D-NT16569

    1g
    1.195,00€
    100mg
    303,00€
    250mg
    487,00€
    500mg
    787,00€
  • 2',3'-Didehydro-2',3'-dideoxyuridine

    CAS :
    <p>2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.</p>
    Formule :C9H10N2O4
    Degré de pureté :Min. 95%
    Masse moléculaire :210.19 g/mol

    Ref: 3D-ND16317

    1g
    2.130,00€
    25mg
    303,00€
    50mg
    336,00€
    100mg
    474,00€
  • N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite


    <p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite is a novel monophosphate nucleoside that is synthesized using an acetylation and methylation reaction. It has a cytidine base and is modified with an acetyl group and a methyl group. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite has been shown to inhibit the growth of cancer cells in vitro, as well as to have antiviral and anticancer activity. This product is available in high purity, high quality, and with modifications to improve its stability.</p>
    Formule :C39H49N4O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :732.8 g/mol

    Ref: 3D-PA09076

    1g
    343,00€
    500mg
    300,00€
  • Guanosine-5'-carboxylic acid

    CAS :
    <p>Guanosine-5'-carboxylic acid (GCA) is a nucleotide that interacts with mammalian cells. It reacts in a vessel to form the antigen, which can then be detected using an antibody. The conformational properties of this molecule are important for its function, and it has been shown to be effective against cancer cells in vivo. GCA has also been shown to interact with toll-like receptor 2 and induce an antibody response.</p>
    Formule :C10H11N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :297.22 g/mol

    Ref: 3D-NG158447

    25mg
    303,00€
    50mg
    416,00€
    100mg
    593,00€
  • N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite

    CAS :
    <p>N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.</p>
    Formule :C43H53N8O6P
    Degré de pureté :Min. 95%
    Couleur et forme :Off white solid.
    Masse moléculaire :808.93 g/mol

    Ref: 3D-PD09020

    250mg
    764,00€
  • 2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å


    <p>2'-Deoxy-5'-O-DMT-guanosine-(iBu)-3'-succinyl CPG 2000 Å is a novel, high quality, and modified nucleoside that can be used in the synthesis of DNA and RNA. It is a phosphoramidite monophosphate that has antiviral and anticancer properties. It can also be used as an activator for the synthesis of oligonucleotides.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND11624

    1g
    303,00€
    5g
    663,00€
    10g
    1.052,00€
  • 3'-Deoxy-3'-fluorocytidine

    CAS :
    <p>3'-Deoxy-3'-fluorocytidine is an activating agent that has been shown to inhibit coxsackie virus and other single-stranded RNA viruses. It is a nucleoside analogue that binds to the enzyme ribofuranoside, preventing the formation of the active site. 3'-Deoxy-3'-fluorocytidine has also been shown to inhibit the biochemical reactions involving S-adenosylhomocysteine hydrolase, which catalyzes the conversion of S-adenosylhomocysteine into adenosine, a precursor for DNA synthesis. Mechanistic studies have indicated that 3'-deoxy-3'-fluorocytidine inhibits enzymatic activity through stereochemical interactions with S-adenosylhomocysteine hydrolase.</p>
    Formule :C9H12FN3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :245.21 g/mol

    Ref: 3D-ND15613

    5mg
    303,00€
    10mg
    355,00€
    25mg
    532,00€
    50mg
    729,00€
    100mg
    805,00€
  • 2’-Deoxy-N2-dimethylguanosine

    CAS :
    <p>2’-Deoxy-N2-dimethylguanosine is a novel antiviral agent that inhibits the replication of human DNA viruses by binding to their diphosphate or monophosphate regions and inhibiting ribonucleotide reductase. It has also been shown to have anticancer properties in vitro.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-AD163057

    100mg
    1.116,00€
    250mg
    1.662,00€
    500mg
    2.562,00€
  • 2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG


    <p>2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a novel chemical compound that has anticancer properties. It is synthesized by the phosphoramidite chemistry and modified with succinyl CPG. This compound can be used as an activator in DNA synthesis, as well as antiviral and anti-inflammatory activities. 2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a nucleoside monophosphate derived from 2'-deoxy-5'-O-dimethoxytrityl adenosine and 3'-succinyl CPG. It has a CAS number of 90161-81-0.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND11631

    1g
    838,00€
    100mg
    303,00€
    250mg
    376,00€
    500mg
    514,00€
  • 2-Iodo-2’-deoxyadenosine

    CAS :
    <p>2-Iodo-2’-deoxyadenosine is a novel nucleoside that is a modified adenosine. It has been shown to possess anticancer activity. 2-Iodo-2’-deoxyadenosine has a high degree of cytotoxicity and can induce apoptosis in cancer cells. This drug also inhibits the growth of herpes simplex virus type 1 (HSV) and HIV, which are both types of viruses that infect humans. The antiviral activity may be due to the inhibition of viral DNA synthesis or RNA transcription. 2-Iodo-2’-deoxyadenosine is synthesized from adenine, iodine, and sulfuric acid with high purity and quality. It is not active against bacteria because it does not inhibit bacterial DNA gyrase or topoisomerase IV enzymes.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-FI144838

    1g
    4.879,00€
  • 8-(p-Chlorophenylthio)-cGMP

    CAS :
    <p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>
    Formule :C16H15ClN5O7PS
    Degré de pureté :Min. 95%
    Masse moléculaire :487.81 g/mol

    Ref: 3D-NC182802

    50mg
    2.113,00€
    100mg
    3.908,00€
  • 2'-TFA-NH-dG

    CAS :
    <p>2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.</p>
    Formule :C12H13F3N6O5
    Degré de pureté :Min. 95%
    Masse moléculaire :378.26 g/mol

    Ref: 3D-NT57541

    100mg
    303,00€
    250mg
    453,00€
    500mg
    651,00€
  • 2,6-Dichloro-7-methylpurine

    CAS :
    <p>2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.</p>
    Formule :C6H4Cl2N4
    Degré de pureté :Min. 95%
    Masse moléculaire :203.03 g/mol

    Ref: 3D-ND29030

    50mg
    303,00€
    100mg
    457,00€
    200mg
    703,00€
    500mg
    1.190,00€
  • 2'-Deoxy-N4,5-dimethylcytidine

    CAS :
    <p>2'-Deoxy-N4,5-dimethylcytidine is an activator that has the ability to activate a variety of nucleoside analogs. The compound is synthetically derived and used as an antiviral agent. It can be modified at the 5' position with phosphate groups or ribonucleosides. 2'-Deoxy-N4,5-dimethylcytidine is also a novel monophosphate nucleoside that has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug inhibits DNA synthesis by preventing the incorporation of diphosphate nucleotides into DNA during DNA replication. 2'-Deoxy-N4,5-dimethylcytidine is not active against RNA synthesis because it does not have any activity at this site.</p>
    Formule :C11H17N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :255.27 g/mol

    Ref: 3D-ND159350

    1mg
    341,00€
  • O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine

    CAS :
    <p>O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a nucleoside phosphoramidite that is used as an antiviral agent. It has been shown to inhibit the replication of RNA viruses and thus inhibit the production of proteins vital for cell division. O6-Benzyl-N2,3-etheno-2'-phenoxythioxomethyl-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine has also been shown to be an anticancer agent by inhibiting DNA synthesis. This compound is synthesized from deoxyribonucleosides and modified with a benzoyl group at the 6 position on the ribose ring. The</p>
    Formule :C38H49N5O7SSi2
    Degré de pureté :Min. 95%
    Masse moléculaire :776.06 g/mol

    Ref: 3D-NB16631

    5mg
    303,00€
    10mg
    336,00€
    25mg
    510,00€
    50mg
    879,00€
    100mg
    1.507,00€
  • Fialuridine 5'-monophosphate

    CAS :
    <p>Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.</p>
    Formule :C9H11FIN2O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :452.07 g/mol

    Ref: 3D-NF16547

    25mg
    1.722,00€
    50mg
    2.745,00€
    100mg
    3.806,00€
  • 2'-Deoxy-3'-O-levulinoylthymidine

    CAS :
    <p>2'-Deoxy-3'-O-levulinoylthymidine is a novel antiviral agent and a synthetic deoxyribonucleoside that is structurally similar to thymidine. It has been studied in vitro and in vivo for its antiviral activity against various viruses, including HIV type 1, HIV type 2, herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), and influenza A virus. 2'-Deoxy-3'-O-levulinoylthymidine has also shown anticancer properties in vitro. This drug inhibits the synthesis of DNA by competing with other nucleotides for incorporation into DNA during the elongation phase of replication. It also inhibits the synthesis of RNA by competing with other nucleotides for incorporation into RNA during transcription.</p>
    Formule :C15H20N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :340.33 g/mol

    Ref: 3D-ND16367

    1g
    303,00€
    2g
    449,00€
    5g
    997,00€
    10g
    1.816,00€
  • N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite

    CAS :
    <p>N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used as an anticancer agent. It has the ability to inhibit DNA synthesis and can be used to treat leukemia, lymphoma, and other cancers. N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT adenosine 3'-CE phosphoramidite is also an antiviral agent that prevents the replication of HIV by interfering with the production of viral RNA. This drug has been shown to have high purity and quality.</p>
    Formule :C54H67N6O8PSi
    Degré de pureté :Min. 95%
    Masse moléculaire :987.2 g/mol

    Ref: 3D-PB09122

    100mg
    864,00€
    250mg
    1.222,00€
    500mg
    2.260,00€
  • 2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å


    <p>2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å is an anticancer drug that is used in the treatment of acute myeloid leukemia. This compound is a modified nucleoside. It has been shown to inhibit the growth of cultured cells and induce apoptosis by causing DNA damage. The anticancer properties of 2'-deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å are mediated by its inhibition of DNA synthesis, RNA synthesis, and protein synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND11635

    1g
    838,00€
    100mg
    303,00€
    250mg
    376,00€
    500mg
    514,00€
  • 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine


    <p>3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine is an antiviral agent that belongs to the class of nucleosides. It is a novel phosphoramidite which can be used in the synthesis of ribonucleosides and deoxyribonucleosides. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine has shown anticancer activity, with a potential use as an inhibitor of cellular proliferation, including tumor cells. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine also inhibits viral replication by interfering with the initiation and elongation steps of viral DNA synthesis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA145610

    25mg
    303,00€
    50mg
    345,00€
    100mg
    533,00€
    250mg
    1.064,00€
  • 2',3'-O-Trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt

    CAS :
    <p>Ribonucleosides are a class of nucleosides that contain ribose as their sugar moiety. The 2' and 3'-O-trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt is an example of a ribonucleoside with the formula CHNO. It has been shown to be active against cancer cells in vitro, but has not yet been used in clinical trials. Ribonucleosides have also been shown to inhibit viral replication and can be used as antiviral agents. Ribonucleosides are also used to synthesize DNA and RNA molecules for use in molecular biology, biochemistry, and genetic engineering.</p>
    Formule :C16H15N8O13P
    Degré de pureté :Min. 95%
    Masse moléculaire :558.31 g/mol

    Ref: 3D-NT29595

    1mg
    394,00€
    2mg
    561,00€
    5mg
    831,00€
    10mg
    1.315,00€
  • γ-[(6-Azidohexyl)-imido]-ATP sodium


    <p>Please enquire for more information about γ-[(6-Azidohexyl)-imido]-ATP sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formule :C16H28N9O12P3•Nax
    Degré de pureté :Min. 95%

    Ref: 3D-NA183120

    1mg
    806,00€
    2mg
    1.085,00€
    5mg
    2.112,00€
    10mg
    3.168,00€
  • 2,2’-Anhydro-5’-O-DMT-uridine

    CAS :
    <p>2,2’-Anhydro-5’-O-DMT-uridine is a high purity synthetic nucleoside that is modified with a hydroxymethyl group in the 2' position. It is a monophosphate and diphosphate derivative of uridine. This nucleoside has antiviral and anticancer properties, as well as the ability to inhibit HIV replication.</p>
    Formule :C30H28N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :528.55 g/mol

    Ref: 3D-NA144786

    5mg
    303,00€
    10mg
    349,00€
    25mg
    621,00€
  • 3'-Deoxy-N6-octanoyladenosine

    CAS :
    <p>3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is &gt;98% and it can be used for research purposes or as a pharmaceutical intermediate.</p>
    Formule :C18H27N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :377.44 g/mol

    Ref: 3D-ND10013

    5mg
    526,00€
    10mg
    864,00€
    25mg
    1.253,00€
    50mg
    1.879,00€
  • 5-Aminoallyl-2'-deoxycytidine


    <p>5-Aminoallyl-2'-deoxycytidine is an activator that has been shown to be a novel anticancer drug. It is an analogue of cytidine and is synthesized by the phosphoramidite method. 5-Aminoallyl-2'-deoxycytidine inhibits viral replication in human cells, but also has antiviral activity against HIV and influenza A virus. The compound has been shown to be active against small cell lung cancer in animal models.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA02925

    1g
    2.440,00€
  • 2'-Deoxy-5'-O-DMT-5-methylcytidine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that can be used to treat cancer. This compound is synthesized by the conversion of 5′-O-dimethoxytrityl (DMT)-2'-deoxycytidine to its 5′-O-DMT phosphoramidite. The phosphoramidite is then reacted with methylene chloride, methanol, and ammonia to form the monophosphate. 2'-Deoxy-5'-O-DMT-5-methylcytidine has been shown to be an effective anticancer drug in vitro and in vivo. It targets DNA synthesis, which prevents the duplication of genetic material necessary for cell division.</p>
    Formule :C31H33N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :White to off-white solid.
    Masse moléculaire :543.63 g/mol

    Ref: 3D-ND08559

    100mg
    303,00€
    250mg
    416,00€
    500mg
    669,00€
  • 8-(4-Aminophenyl)-2'-deoxyguanosine


    <p>8-(4-Aminophenyl)-2'-deoxyguanosine is an Activator that has novel properties. It is a diphosphate of 8-(4-Aminophenyl)thymidine and is also known as 8-APT. It has been shown to have anticancer and antiviral activity in animal models, and it may be a potential treatment for HIV infection. The chemical name for 8-APT is 2'-deoxyguanosine, 8-(4-aminophenyl)-, (8R*,9S*)-.</p>
    Formule :C16H18N6O4
    Degré de pureté :Min. 95%
    Masse moléculaire :358.35 g/mol

    Ref: 3D-NA04648

    25mg
    1.879,00€
    50mg
    2.928,00€
    100mg
    3.806,00€
  • 5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil

    CAS :
    <p>5-Fluoro-1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil (5FUA) is a monophosphate nucleoside that inhibits viral replication. It is phosphorylated by the viral enzyme 3' to 5' exonuclease and then acts as a competitive inhibitor of the natural substrate, diphosphate, at the active site of DNA polymerase. The result is inhibition of viral DNA synthesis and replication. 5FUA has been shown to be active against a variety of viruses including herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, and human immunodeficiency virus type 1. This drug has also been shown to inhibit cancer cell proliferation in vitro.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NF58423

    1g
    300,00€
  • N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine


    <p>N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine is a synthetic nucleoside that inhibits the enzyme ribonucleotide reductase. It has antiviral and anticancer activities.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB158805

    100mg
    303,00€
  • 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å


    <p>The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND11621

    1g
    303,00€
  • 5-Bromo-2,4-di(benzyloxy)pyrimidine

    CAS :
    <p>5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.</p>
    Formule :C18H15BrN2O2
    Degré de pureté :Min. 95%
    Masse moléculaire :371.23 g/mol

    Ref: 3D-NB57419

    1g
    478,00€
    2g
    725,00€
    5g
    1.067,00€
    500mg
    300,00€
  • 2'-Deoxyguanosine-5'-monophosphate free acid

    CAS :
    <p>2'-Deoxyguanosine-5'-monophosphate free acid (dGMP) is a nucleotide that can be used as a substrate to measure the activity of protein kinase C. It is also a precursor in DNA synthesis, and its incorporation into DNA is catalyzed by polymerase chain reaction. 2'-Deoxyguanosine-5'-monophosphate free acid has been shown to inhibit transcriptional regulation, which may be related to its interaction with nuclear DNA. Furthermore, it has been shown to have an antioxidant effect due to its ability to donate electrons. 2'-Deoxyguanosine-5'-monophosphate free acid has also been shown to react with sodium salts in plasma mass spectrometry experiments, and titration calorimetry experiments have shown that it reacts with calcium ions in vitro.br&gt;</p>
    Formule :C10H14N5O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :347.22 g/mol

    Ref: 3D-ND29406

    1g
    473,00€
    2g
    701,00€
  • N6-(4-Methyoxybenzoyl)adenosine

    CAS :
    <p>N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.</p>
    Formule :C18H19N5O6
    Degré de pureté :Min. 95%
    Masse moléculaire :401.37 g/mol

    Ref: 3D-NP57529

    100mg
    303,00€
    250mg
    406,00€
    500mg
    586,00€
  • 3-Deazauridine-5'-triphosphate triethylamine salt

    CAS :
    <p>3-Deazauridine-5'-triphosphate triethylamine salt is a xanthosine analog that has been used as a biochemical reagent in animals and humans. It is postulated to be a potential cancer therapeutic agent because of its ability to inhibit DNA synthesis and cell division. 3-Deazauridine-5'-triphosphate triethylamine salt inhibits the biosynthesis of uridine in leukemic mice, hamster V79 cells, and mammalian cells. This drug inhibits the incorporation of uracil into RNA by competitive inhibition with respect to ATP. 3DATTP also inhibits the incorporation of thymidine into DNA by competitive inhibition with respect to dCTP.</p>
    Formule :C10H16NO15P3
    Degré de pureté :Min. 95%
    Masse moléculaire :483.15 g/mol

    Ref: 3D-ND74958

    1mg
    303,00€
    5mg
    626,00€
    10mg
    949,00€