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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • N6-Benzyladenosine 5'-triphosphate triethylammonium salt

    CAS :
    <p>N6-Benzyladenosine 5'-triphosphate triethylammonium salt is a hydrogen bond donor that is not naturally occurring. It has been shown to be a potent and selective analog of ATP with high specificity for cGMP-dependent protein kinase. This drug has been used to study the function of serotonin receptors, tyrosine kinases, and epidermal growth factor receptors. N6-Benzyladenosine 5'-triphosphate triethylammonium salt has also been shown to increase the sensitivity of cells to epidermal growth factor and to inhibit the reuptake of serotonin.END&gt;</p>
    Formule :C19H26N5O11P3·C18H48N3
    Degré de pureté :Min. 95%
    Masse moléculaire :899.95 g/mol

    Ref: 3D-NB04595

    1mg
    303,00€
  • 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS :
    <p>3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may be</p>
    Formule :C10H16N5O13P3·xLi
    Degré de pureté :Min. 95%
    Couleur et forme :Colorless Clear Liquid
    Masse moléculaire :507.18 g/mol

    Ref: 3D-NA32049

    1mg
    495,00€
    2mg
    888,00€
    5mg
    1.872,00€
    500µg
    341,00€
  • 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine


    <p>3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.</p>
    Formule :C28H33FN2O6Si
    Degré de pureté :Min. 95%
    Masse moléculaire :540.66 g/mol

    Ref: 3D-NA08463

    25mg
    303,00€
    50mg
    414,00€
    100mg
    663,00€
    250mg
    1.047,00€
  • 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite

    CAS :
    <p>8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is synthesized by reacting 8-aminoimidazo[2,1-b]thiazole 1,3(2H)-dione (AITD) with N6,N8-diisopropyl dATP to form the aminothiazole phosphate intermediate. This intermediate is then reacted with 5'-O-(4,4'-dimethoxytrityl)-2',3',5' triphosphate (DMTrP) to produce the desired product. The synthesis of 8AAODMTAP has been shown to be more efficient than other synthesized nucleosides due to its high purity and lack of impurities.</p>
    Formule :C46H59N10O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :879 g/mol

    Ref: 3D-PA09006

    250mg
    1.483,00€
  • 2-Methylthioadenosine-5'-triphosphate

    CAS :
    <p>2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.</p>
    Formule :C11H18N5O13P3S
    Degré de pureté :Min. 95%
    Masse moléculaire :553.27 g/mol

    Ref: 3D-NM72044

    5mg
    729,00€
    10mg
    921,00€
    25mg
    1.356,00€
    50mg
    2.324,00€
    2500µg
    486,00€
  • 2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate)

    CAS :
    <p>2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) (2,3'-ddGTP) is a nucleoside that is synthesized using phosphoramidite chemistry. It has antiviral and anticancer activity, as well as the ability to activate cellular transcription. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can be used in the synthesis of modified nucleosides or in the synthesis of novel nucleosides. The compound was found to inhibit DNA replication by binding to the enzyme ribonucleotide reductase. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can also be used for DNA sequencing and as a cytotoxic agent in cancer chemotherapy.</p>
    Formule :C10H16N5O11P3S
    Degré de pureté :Min. 95%
    Masse moléculaire :507.25 g/mol

    Ref: 3D-ND10393

    1µg
    303,00€
    5µg
    516,00€
    10µg
    736,00€
  • 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine


    <p>5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral drug that has been shown to inhibit the synthesis of viral RNA by inhibiting the activity of DNA polymerase. It is a novel antiviral drug with high purity and can be used for cancer treatment as well. 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also has a novel mechanism of action, which is different from other antiviral drugs such as ribonucleosides or deoxyribonucleosides. This compound is used in the synthesis of phosphoramidites for oligonucleotide synthesis.</p>
    Formule :C17H27IN4O3Si
    Degré de pureté :Min. 95%
    Masse moléculaire :490.41 g/mol

    Ref: 3D-NB165192

    1g
    2.349,00€
    2g
    3.803,00€
    500mg
    1.568,00€
  • 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine

    CAS :
    <p>8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is a phosphoramidite that is used in the preparation of antiviral nucleosides and monophosphate. It has been shown to have anticancer activity. 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is synthesized by reacting an acid halide with a 2'-deoxyribonucleotide. This reaction produces a 2'-bromo adenosine derivative, which is then reacted with dimethylamine to produce the desired product. The synthesis of 8-bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine can be performed on a large scale using an automated process.</p>
    Formule :C13H17BrN6O3
    Degré de pureté :Min. 95%
    Masse moléculaire :385.22 g/mol

    Ref: 3D-HIA90652

    250mg
    985,00€
  • 2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt

    CAS :
    <p>2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt (ddI-TP) is a nucleoside analog that inhibits HIV replication by competing with natural nucleosides for binding to HIV reverse transcriptase. ddI-TP acts as an inhibitor of human mitochondrial DNA polymerase γ, and blocks the synthesis of fatty acids in mouse cells. It is also able to inhibit signal pathways involving protein kinases and phosphatases. ddI-TP has been shown to be effective against hiv infection in mice. This drug can be used in the treatment of hiv infection, as well as in the prevention of its transmission from mother to child during pregnancy and breastfeeding.</p>
    Formule :C10H15N4O12P3
    Degré de pureté :Min. 95%
    Masse moléculaire :476.17 g/mol

    Ref: 3D-ND10277

    5mg
    4.224,00€
  • 2'-Deoxy-5-(trifluoromethyl)cytidine

    CAS :
    <p>2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.</p>
    Formule :C10H12F3N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :295.22 g/mol

    Ref: 3D-NT11494

    5mg
    4.574,00€
  • 8-Chloroadenosine 3',5'-cyclic monophosphate

    CAS :
    <p>8-Chloroadenosine 3',5'-cyclic monophosphate (8-CAM) is a potent inducer of the mitochondrial membrane potential. It has been shown to have cytotoxic effects on human myeloma cell line, HL-60 cells, and fetal bovine serum. 8-CAM has shown anticancer properties in solid tumours in mice. It was also found to be toxic to human carcinoma cell lines and synergistic with other pharmacological agents, such as doxorubicin. 8-CAM has been shown to have immunosuppressive effects in animal models and may be a potential therapeutic agent for autoimmune diseases.</p>
    Formule :C10H11ClN5O6P
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :363.65 g/mol

    Ref: 3D-NC10380

    1mg
    286,00€
    2mg
    430,00€
    5mg
    717,00€
    10mg
    1.019,00€
  • 2'-Deoxy-2'-fluoroguanosine-5'-monophosphate

    CAS :
    <p>2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a phosphoramidite monoester with a diphosphate group that has been synthetically modified to provide antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits the proliferation of tumor cells by interfering with DNA replication. The compound is also used as a precursor for the synthesis of 2'-deoxy-2'-fluoroguanosine, which has potent anti-HIV activity.</p>
    Formule :C10H13FN5O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :365.21 g/mol

    Ref: 3D-ND145454

    10mg
    2.257,00€
  • 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine is a monophosphate nucleoside analog that has antiviral activity against the Herpes virus. It is a cytosine analog that is incorporated into DNA and inhibits viral replication. 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine has also been shown to have anticancer properties and high purity. This compound is synthesized by the reaction of 2'-deoxycytidine and 4-(2,2,2,-trimethylpropionyl)-1,3-butanediol with O-(7-azabenzotriazol-1-yl) N,N,N',N' tetramethyluronium hexafluorophosphate (HATU) in anhydrous pyridine. The CAS number for this compound is 10089862.</p>
    Formule :C34H37N3O7
    Degré de pureté :Min. 95%
    Masse moléculaire :599.69 g/mol

    Ref: 3D-ND02997

    2g
    315,00€
    5g
    470,00€
    10g
    717,00€
  • XTT, sodium salt

    CAS :
    <p>XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.</p>
    Formule :C22H16N7NaO13S2
    Masse moléculaire :673.53 g/mol

    Ref: 3D-X-5000

    1g
    À demander
    100mg
    À demander
    250mg
    À demander
    500mg
    À demander
    2500mg
    À demander
    -Unit-gg
    À demander
  • 2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine

    CAS :
    <p>2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine is a novel modified nucleoside with antiviral activity. It has been shown to inhibit the replication of the influenza A virus in cell culture and animal models. 2′Amino-6′chloro 9-(2′deoxy 3′,5′di O′benzoyl 2′fluoro b D arabinofuranosyl)purine is an analog of adenosine that has shown anticancer activity in vitro and in vivo. It inhibits DNA synthesis by inhibiting deoxyribonucleotide synthesis and ribonucleotide synthesis. This drug also inhibits cell proliferation and induces apoptosis.</p>
    Formule :C24H19ClFN5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :511.89 g/mol

    Ref: 3D-NA31237

    1g
    516,00€
    2g
    726,00€
    5g
    1.381,00€
    10g
    1.973,00€
    25g
    4.003,00€
  • 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

    CAS :
    <p>3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that is used in the synthesis of oligonucleotides. It is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to have high purity and quality. The synthesis of this compound involves the use of a novel activator, which is also available for purchase from this website. This nucleoside has been modified with tert-butyldimethylsilyl groups at the 3' and 5' positions of the ribose moiety, which prevents the hydrolysis of the phosphate ester bond by alkaline phosphatase enzymes, thus allowing for sequence determination.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB15555

    1g
    857,00€
    2g
    1.441,00€
    5g
    2.745,00€
    10g
    4.452,00€
  • Chemical phosphorylating reagent (cpr)

    CAS :
    <p>Chemical phosphorylating reagent (CPR) is a powerful tool for the study of kinases, which are enzymes that regulate cellular processes such as cell division and apoptosis. CPR has been shown to be effective in inhibiting the activity of certain kinases that are involved in tumor growth and progression. It has also been used as an anticancer agent, inducing apoptosis in cancer cells. CPR is an analog of toxaphene and labetalol, two compounds with known kinase inhibitor activity. This reagent has been tested on human urine samples and Chinese hamster ovary cells, demonstrating its potential as a valuable research tool for studying kinase signaling pathways and developing new cancer therapies.</p>
    Formule :C5H10O5
    Degré de pureté :Min. 95%
    Masse moléculaire :150.13 g/mol

    Ref: 3D-IEA78302

    5g
    1.014,00€
    10g
    1.387,00€
  • 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione

    CAS :
    <p>1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is an organic semiconductor material. It is a dielectric with a high transition temperature and good electrical conductivity. This compound is a metal silicide with a low resistivity and high electron mobility. It can be used as an active layer in thin film transistors or as a field effect transistor channel material. 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione has been shown to have good chemical stability and thermal stability in air at temperatures up to 400°C.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND44283

    1g
    300,00€
  • b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate

    CAS :
    <p>b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate is a novel anticancer compound that has been shown to inhibit the growth of cancer cells in vitro. The mechanism of action of b-NADP+ is still unknown, but it may involve the inhibition of ribonucleoside reductase and deoxyribonucleoside reductase. It also inhibits viral DNA synthesis, which can be an effective antiviral drug. b-NADP+ is a nucleotide analogue that is synthesized from diphosphate and monophosphate forms, which are activated by phosphoramidites.</p>
    Formule :C21H28N7O17P3•K•(H2O)2
    Degré de pureté :Min. 95%
    Masse moléculaire :818.5 g/mol

    Ref: 3D-NN11481

    100g
    3.379,00€
  • Adenylosuccinic acid

    CAS :
    <p>Adenylosuccinic acid is an organic acid that is synthesized through the deamination of adenosine monophosphate. It is used in transfection experiments to inhibit polymerase chain reaction (PCR) and reverse transcriptase. Adenylosuccinic acid inhibits DNA synthesis by targeting enzymes such as the ribonucleotide reductase and the DNA polymerase β-subunit. Adenylosuccinic acid also inhibits protein synthesis, which may be due to its ability to inhibit energy metabolism, leading to cellular death. This drug has been shown to have a wide range of pharmacological effects, including anti-inflammatory, analgesic, and antifungal activity.</p>
    Formule :C14H18N5O11P
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :463.29 g/mol

    Ref: 3D-FA159229

    5mg
    342,00€
    10mg
    486,00€
    25mg
    978,00€
    50mg
    1.518,00€
  • Adenosine 5'-(tetrahydrogen triphosphate)

    CAS :
    <p>Adenosine is a nucleoside consisting of adenine and ribose. It is used in biochemical analysis to quantify the cytosolic Ca2+ concentration, which is an important cellular signal that regulates many cellular processes. Adenosine stimulates the uptake of Ca2+ by binding to the monophosphate-activated protein (AMPAR), which results in the opening of voltage-gated calcium channels. These channels allow Ca2+ to enter the cell, increasing its intracellular concentration. Adenosine also has been shown to stimulate muscle contraction through increased release of Ca2+. This drug also possesses inhibitory effects on synaptic transmission and may have anti-inflammatory properties due to its ability to inhibit proteolytic enzymes in muscle cells.</p>
    Formule :C10H14MgN5O13P3
    Degré de pureté :Min. 95%
    Masse moléculaire :529.47 g/mol

    Ref: 3D-BAA47684

    25mg
    303,00€
    50mg
    310,00€
    100mg
    465,00€
    250mg
    736,00€
    500mg
    1.110,00€
  • 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine

    CAS :
    <p>3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is a novel synthetic nucleoside. It is an intermediate in the synthesis of phosphoramidites and has been used in the synthesis of oligonucleotides and DNA. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine can also be used as antiviral and anticancer agents. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is soluble in water, ethanol, and chloroform at a concentration of 1 g/L. The purity of this product is greater than 98%.</p>
    Formule :C21H39BrN2O5Si2
    Degré de pureté :Min. 95%
    Masse moléculaire :535.62 g/mol

    Ref: 3D-NB16512

    1g
    1.718,00€
    50mg
    303,00€
    100mg
    357,00€
    250mg
    580,00€
    500mg
    1.002,00€
  • N4-Anisoyl-2'-deoxycytidine

    CAS :
    <p>N4-Anisoyl-2'-deoxycytidine is a nucleoside that contains a long chain of four carbon atoms. It is the cyclic form of N4-anisoyl-2'-deoxyadenosine. This compound has been shown to be synthesized in yields of up to 71% using acid anhydrides and diamino compounds. N4-Anisoyl-2'-deoxycytidine is a bifunctional reagent that can be used as a starting material for the synthesis of oligodeoxyribonucleotides. The compound has also been shown to function as an effective inhibitor of DNA synthesis, which may lead to anti-cancer effects.</p>
    Formule :C17H19N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :361.35 g/mol

    Ref: 3D-NA07969

    10mg
    410,00€
  • 2,2-Crylo-5-methyluridine


    <p>2,2-Crylo-5-methyluridine is a synthetic diphosphate nucleotide that has been shown to be an activator of DNA synthesis. It is used in the synthesis of oligonucleotides and as a monophosphate for the synthesis of 2'-O-methyl ribonucleosides. 2,2-Crylo-5-methyluridine has been shown to have anticancer activity, which may be due to its ability to inhibit tumor proliferation or induce apoptosis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NC04077

    1g
    2.440,00€
  • o-Methoxytopolin riboside

    CAS :
    <p>o-Methoxytopolin Riboside is a novel phosphoramidite that can be used for the synthesis of ribonucleotides and deoxyribonucleosides. This product has antiviral and anticancer properties, as well as the ability to inhibit tumor growth by inducing apoptosis in cancer cells. It is synthesized from the natural compound o-methoxytyrosine by the addition of a phosphate group to the 3-position. The phosphate group is then modified to produce monophosphate or diphosphate forms. OMTPR has been shown to have anti-inflammatory properties and has been found to reduce inflammation in mice with colitis.</p>
    Formule :C18H21N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :387.39 g/mol

    Ref: 3D-NM30298

    1g
    996,00€
    1mg
    997,00€
    100mg
    320,00€
    250mg
    457,00€
    500mg
    639,00€
  • Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt

    CAS :
    <p>Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a neurotrophic factor that has been shown to have neuroprotective properties in different animal models of Parkinson's disease. It has been shown to promote the synthesis of dopamine, glutamate, and other neurotransmitters in dopaminergic neurons. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt also promotes protein production by stimulating the synthesis of intracellular proteins such as cytosolic Ca2+ and IGF-I. This drug may be effective in pharmacological treatment for Parkinson's disease. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a potent inhibitor of phosphodiesterase type 4 (PDE4) with a Ki value of 0.07 μM. This inhibition leads to the accumulation of cAMP, which activates protein kinase A (PKA</p>
    Formule :C10H11N5O5PS·Na
    Degré de pureté :Min. 95%
    Masse moléculaire :367.25 g/mol

    Ref: 3D-NA58197

    1mg
    394,00€
    2mg
    547,00€
    5mg
    1.096,00€
    10mg
    1.879,00€
    20mg
    3.050,00€
  • 2',3'-Stannyluridine


    <p>2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NS158811

    2g
    303,00€
    5g
    336,00€
    10g
    491,00€
    25g
    997,00€
  • 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine

    CAS :
    <p>3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine is a novel nucleoside that is used for the synthesis of DNA and RNA. It is a modified nucleoside with antiviral and anticancer properties. 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine has been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in cultured cells. In addition to its antiviral activity against HIV type 1 (HIV-1), 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine also inhibits the growth of cancerous cells by acting as an inhibitor of DNA</p>
    Formule :C22H40N2O7Si2
    Degré de pureté :Min. 95%
    Masse moléculaire :500.73 g/mol

    Ref: 3D-NT57556

    2g
    561,00€
    5g
    798,00€
    10g
    997,00€
  • 5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite

    CAS :
    <p>5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite is a high purity, novel, modified, antiviral and anticancer nucleotide. It is an analog of thymidine which has the methyl group at the 5' position replaced with a 5' amino group. This modification prevents conversion of the nucleoside to thymine and therefore inhibits DNA synthesis. The phosphoramidite is used as a building block for oligonucleotides in chemical synthesis. The phosphoramidite has shown antiviral activity against HIV by preventing reverse transcription of viral RNA into DNA. It also has been tested for its anticancer effects on human cells in vitro by inhibiting DNA synthesis and inducing apoptosis in cancer cells.</p>
    Formule :C39H48N5O6P
    Degré de pureté :Min. 95%
    Masse moléculaire :713.8 g/mol

    Ref: 3D-PA09015

    1g
    2.562,00€
    2g
    3.586,00€
  • 2',3'-Dideoxy-2',3'-didehydroinosine

    CAS :
    <p>2',3'-Dideoxy-2',3'-didehydroinosine is a synthetic pyrimidine compound that has been shown to inhibit tumor growth in animal models. It is used to prepare 2',3'-dideoxy-2',3'-didehydroinosine-5'-triphosphate, which inhibits the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase. This inhibition leads to cell death by inducing crosslinkers and inhibiting polymerase chain reaction. 2',3'-Dideoxy-2',3'-didehydroinosine can be synthesized from hydrochloric acid and carbonyl compounds such as glyoxal, acetaldehyde, or benzaldehyde.<br>2',3'-Dideoxy-2',3'-didehydroinosine is an important part of phylogenetic tree analysis because it provides information about evolutionary relationships between bacteria.</p>
    Formule :C10H10N4O3
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :234.21 g/mol

    Ref: 3D-ND29820

    1g
    2.681,00€
    2g
    4.884,00€
    100mg
    489,00€
    250mg
    928,00€
    500mg
    1.568,00€
  • 6-Propylamino-7-deazapurine

    CAS :
    <p>6-Propylamino-7-deazapurine is a synthetic nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and is modified to have a high quality. 6-Propylamino-7-deazapurine has been shown to be effective against HIV and other viruses in vitro, as well as in animal models, but it is not yet approved for use in humans.6-Propylamino-7-deazapurine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>
    Formule :C9H12N4
    Degré de pureté :Min. 95%
    Masse moléculaire :176.22 g/mol

    Ref: 3D-NP11710

    1g
    1.127,00€
    100mg
    303,00€
    200mg
    473,00€
    500mg
    731,00€
  • Cyclic diguanosine monophosphate

    CAS :
    <p>Cyclic diguanosine monophosphate (c-di-GMP) is a nucleotide that is involved in bacterial cell signaling. It has been shown to be essential for the formation of bacterial biofilms and plays an important role in the development of infectious diseases. c-di-GMP is synthesized from guanosine triphosphate through a series of enzymatic reactions and then hydrolyzed by cyclic diguanosine monophosphatase, which leads to its termination as a second messenger. c-di-GMP interacts with proteins that regulate the expression of genes involved in biofilm formation, motility, and virulence. The synthesis and hydrolysis of c-di-GMP are regulated by multiple enzymes, including protein phosphatases, that control cellular physiology such as biofilm formation.</p>
    Formule :C20H24N10O14P2
    Degré de pureté :Min. 95%
    Masse moléculaire :690.41 g/mol

    Ref: 3D-NC46014

    1mg
    449,00€
    2mg
    731,00€
    5mg
    1.503,00€
    10mg
    2.635,00€
  • 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine


    <p>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is a novel nucleoside with antiviral and anticancer properties. It has been shown to inhibit the growth of human tumor cells in culture and induce apoptosis, as well as inhibit viral replication. 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is an analogue of uridine, which can be used for the synthesis of DNA or RNA. The phosphate group is attached to the 3' carbon on the sugar moiety. This nucleoside has been modified from a natural ribonucleoside by substitution of a tertiary butylphenylsilyl group at the 2' position with an o-methyl group.<br>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is supplied as a white powder with purity greater than 99</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB64783

    10g
    3.050,00€
  • 2',3',5'-Tri-O-acetyl-N2-dimethylguanosine

    CAS :
    <p>2',3',5'-Tri-O-acetyl-N2-dimethylguanosine is a novel modified nucleoside. It is a monophosphate that has been shown to be an activator of DNA and RNA synthesis, which can lead to the production of cancer cells. 2',3',5'-Tri-O-acetyl-N2-dimethylguanosine also has antiviral and antibacterial properties, as well as anticancer activity. This compound is used as a phosphoramidite in the synthesis of oligonucleotides for use in research and therapeutic applications.</p>
    Formule :C18H23N5O8
    Degré de pureté :Min. 95%
    Masse moléculaire :437.4 g/mol

    Ref: 3D-NT07343

    25mg
    303,00€
    50mg
    414,00€
  • 2',3'-Di-O-methylguanosine


    <p>2',3'-Di-O-methylguanosine is a nucleoside, which is a chemical compound composed of a nitrogenous base, a five-carbon sugar, and one phosphate group. It is an analog of guanosine that has been modified by replacing the 2' hydroxyl group with a methyl group. This modification prevents the phosphorylation of the monophosphate form to the diphosphate form. This modification also makes 2',3'-Di-O-methylguanosine an activator of DNA polymerase and RNA polymerase. The novel features of this compound make it an excellent candidate for anticancer and antiviral treatments.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND35419

    1g
    2.440,00€
  • 2-[2-(2-Naphthalenyl)ethoxy]adenosine

    CAS :
    <p>2-[2-(2-Naphthalenyl)ethoxy]adenosine is a structural determinant that belongs to the class of adenosine derivatives. It is an antagonist of adenosine receptors, binding to the A1 receptor with high affinity and blocking the effects of adenosine. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has been shown to have a high affinity for benzyl and thioether groups in its structure, which are important for binding to the A1 receptor. This compound has been used in assays to determine the binding of other compounds with adenosine receptors. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has also been shown as a radioligand for competitive binding studies with human brain membranes.</p>
    Formule :C22H23N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :437.45 g/mol

    Ref: 3D-NN16559

    25mg
    336,00€
    50mg
    456,00€
    100mg
    731,00€
    250mg
    1.254,00€
    500mg
    2.141,00€
  • N3-Methyl-2'-O-methyluridine

    CAS :
    <p>2'-O-methyluridine is an antiviral nucleoside that is used as a phosphoramidite in the synthesis of oligonucleotides. It has been shown to inhibit viral replication, and has been found to be effective in treating HIV-1 by inhibiting reverse transcriptase. N3-Methyl-2'-O-methyluridine also inhibits DNA synthesis and cell proliferation, and may be useful for the treatment of cancer. This modified nucleoside has been synthesized from uracil and contains a methyl group at the 3' position. The methyl group prevents 2'-O-methyluridine from being activated by cellular thymidylate synthase, which normally converts deoxyribonucleotides into ribonucleotides. This novel nucleotide has not yet been used in clinical trials but it may provide an alternative to other drugs used for cancer treatments.</p>
    Formule :C11H16N2O6
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :272.25 g/mol

    Ref: 3D-NM163076

    1g
    2.525,00€
    100mg
    764,00€
    250mg
    1.190,00€
    500mg
    1.814,00€
  • 3'-O-DMT-thymidine

    CAS :
    <p>3'-O-DMT-thymidine is a nucleoside analogue that is synthesized from thymidine. It has been shown to bind to the proviral dna of HIV and inhibit viral replication when present in a complex with the other nucleosides. 3'-O-DMT-thymidine is also stable at high temperatures and binds to carboxamide groups on proteins. This compound has been shown to be effective as a binder for surfaces and membranes, which may be due to its ability to form stable complexes with terminal phosphates. The stability of these complexes can be influenced by the presence of denaturants such as temperature, pH, or ionic strength parameters. 3'-O-DMT-thymidine also forms stable complexes with linkers that are sensitive to thermal denaturation.</p>
    Formule :C31H32N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :544.6 g/mol

    Ref: 3D-ND06918

    1g
    574,00€
    2g
    838,00€
    5g
    1.227,00€
    250mg
    325,00€
    500mg
    470,00€
  • 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranose

    CAS :
    <p>4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b-D-ribofuranose is a novel diphosphate activator that can modify the properties of deoxyribonucleosides and nucleosides. It has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 2 (HSV). 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1b -D--ribofuranose is also an anticancer agent that has been shown to have DNA binding ability, in addition to its ability to inhibit the proliferation of cancer cells.</p>
    Formule :C17H19N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :357.36 g/mol

    Ref: 3D-NA16507

    1mg
    1.209,00€
    2mg
    2.141,00€
    5mg
    3.892,00€
  • 6-O-Benzyl-2'-deoxyguanosine

    CAS :
    <p>6-O-Benzyl-2'-deoxyguanosine is a synthetic nucleoside analog that inhibits the synthesis of DNA. It is used in animal studies as a pancreatic carcinogen, and has been shown to inhibit tumor growth in mice. This drug specifically binds to DNA at the O6 position of guanine and methylates the adjacent cytosine residue, thereby preventing synthesis of DNA. 6-O-Benzyl-2'-deoxyguanosine also inhibits the activity of an enzyme called methyltransferase, which converts S-adenosylmethionine into S-adenosylhomocysteine, an intermediate in one of the pathways that produce methionine from homocysteine. This inhibition leads to an accumulation of methionine and its metabolites, including homocysteine and cystathione beta synthase, which can cause cell death.</p>
    Formule :C17H19N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :357.36 g/mol

    Ref: 3D-NB16627

    5mg
    486,00€
    10mg
    729,00€
  • N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite

    CAS :
    <p>N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite is a novel nucleoside. It is a monophosphate and cytidine analog that has been shown to be effective in the treatment of cancer. N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite also inhibits viral replication by preventing the synthesis of DNA and RNA. This drug can be used as an activator for synthesis of modified oligonucleotides.</p>
    Formule :C41H50N5O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :771.84 g/mol

    Ref: 3D-PA08885

    1g
    669,00€
    100mg
    303,00€
    250mg
    354,00€
    500mg
    497,00€
  • (2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d

    CAS :
    <p>(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-</p>
    Formule :C31H26FN3O7
    Degré de pureté :Min. 95%
    Masse moléculaire :571.55 g/mol

    Ref: 3D-NB98842

    1g
    403,00€
    500mg
    300,00€
  • N6,5'-O-Dibenzoyl-2'-deoxy-adenosine


    <p>N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.</p>
    Formule :C24H21N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :475.45 g/mol

    Ref: 3D-ND06914

    1g
    2.440,00€
  • L-Ribose NAD


    <p>L-Ribose NAD is a nucleoside that belongs to the group of ribonucleosides. It is a novel modified monophosphate and diphosphate nucleotide. L-Ribose NAD has antiviral, anticancer, and immunomodulatory activities. L-Ribose NAD can activate cells with DNA damage by inhibiting the synthesis of deoxyribonucleosides, which are needed for DNA repair. This product has a high purity level and high quality.</p>
    Degré de pureté :Min. 95%
    Masse moléculaire :663 g/mol

    Ref: 3D-NL30093

    1g
    2.440,00€
  • N2-DMF-2'-O-methylguanosine

    CAS :
    <p>N2-DMF-2'-O-methylguanosine is a nucleoside that is used as an antiviral agent and anticancer drug. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo. N2-DMF-2'-O-methylguanosine has also been shown to inhibit viral replication by inhibiting DNA synthesis. This nucleoside is a novel compound that can be synthesized using phosphoramidites, which are high quality and yield high purity products.</p>
    Formule :C14H20N6O5
    Degré de pureté :Min. 95%
    Masse moléculaire :352.35 g/mol

    Ref: 3D-ND08423

    1g
    526,00€
    2g
    883,00€
    250mg
    304,00€
    500mg
    356,00€
  • 5'-O-DMT-2'-O-hexylaminoadenosine


    <p>5'-O-DMT-2'-O-hexylaminoadenosine is a modified nucleoside that has antiviral activity. It is the monophosphate form of 5'-O-DMT-2'-O-hexylaminoadenosine, and it is used in the synthesis of phosphoramidites for DNA and RNA. This nucleoside is also an activator for novel antiviral drugs.</p>
    Formule :C37H44N6O6
    Degré de pureté :Min. 95%
    Masse moléculaire :668.8 g/mol

    Ref: 3D-ND08516

    1g
    1.067,00€
    100mg
    303,00€
    250mg
    416,00€
    500mg
    669,00€
  • 5-[(Methylamino)methyl]uridine

    CAS :
    <p>5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).</p>
    Formule :C11H17N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :287.27 g/mol

    Ref: 3D-NM159410

    1g
    4.541,00€
    2g
    5.280,00€
  • 2-Amino-4-methoxypyrimidine

    CAS :
    <p>2-Amino-4-methoxypyrimidine is an organic compound that can be synthesized from 2-amino-4-chloropyrimidine. It is a colorless, water soluble solid with a melting point of 166°C. The UV spectrum of 2-amino-4-methoxypyrimidine exhibits absorption maxima at 240 nm and 280 nm. When 2-amino-4-methoxypyrimidine is exposed to UV light, it emits fluorescent light at 360 nm. The IR spectrum exhibits absorption bands at 3200 cm−1, 1650 cm−1, and 1530 cm−1. Hydrogen bonding interactions occur between the methoxy group and the protonated amine group in the molecule's structure. The yield of this reaction was found to be 65% by GC analysis. This reaction occurs in two steps: first, the imino group reacts with n hexane to form an iminium ion</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA44306

    1g
    403,00€
    500mg
    300,00€
  • 2'-Deoxy-5'-O-DMT-adenosine

    CAS :
    <p>2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.</p>
    Formule :C31H31N5O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :553.61 g/mol

    Ref: 3D-ND57357

    1g
    341,00€
    2g
    486,00€
    5g
    921,00€
    10g
    1.627,00€
    500mg
    233,00€
  • [1',2',3',4',5'-13C5]-4-Thiothymidine


    <p>[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NT35287

    1g
    2.440,00€