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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3567 produits trouvés pour "Nucléosides"

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  • 2'-Deoxy-1,N6-dimethyladenosine


    <p>2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND159725

    100mg
    3.660,00€
  • Inosine-3',5'-cyclic-monophosphate free acid

    CAS :
    <p>Inosine-3',5'-cyclic-monophosphate free acid is an ester of inosine 3',5'-cyclic-monophosphate that is structurally related to adenosine. It has been shown to have a physiological function as a cyclic nucleotide phosphodiesterase inhibitor, and also inhibits voltage-dependent calcium channels. Inosine-3',5'-cyclic-monophosphate free acid has been shown to be effective against infectious diseases, such as Mycobacterium tuberculosis and Galleria mellonella. It has also been shown to reduce the production of peptide hormones, nucleotides, and cyclic AMP (cAMP). Inosine-3',5'-cyclic-monophosphate free acid does not exhibit any pharmacological activity on its own but can modulate the activities of other pharmacological agents.</p>
    Formule :C10H11N4O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :330.19 g/mol

    Ref: 3D-NI10382

    1mg
    303,00€
    5mg
    876,00€
    10mg
    1.320,00€
  • N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite

    CAS :
    <p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.</p>
    Formule :C52H66N5O9PSi
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :964.19 g/mol

    Ref: 3D-PB08708

    1g
    701,00€
    2g
    967,00€
    250mg
    303,00€
    500mg
    430,00€
  • AFB-guanine

    CAS :
    <p>AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.</p>
    Formule :C22H17N5O8
    Degré de pureté :Min. 95%
    Masse moléculaire :479.4 g/mol

    Ref: 3D-NA17231

    1mg
    2.141,00€
    2mg
    3.892,00€
  • 5-Methylcytidine HCl


    <p>5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.</p>
    Formule :C10H15N3O5·HCl
    Degré de pureté :Min. 95%
    Masse moléculaire :293.7 g/mol

    Ref: 3D-NM08573

    1g
    669,00€
    250mg
    304,00€
    500mg
    416,00€
  • 2-[2-(4-Fluorophenyl)ethoxy]adenosine

    CAS :
    <p>2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.</p>
    Formule :C18H20FN5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :405.38 g/mol

    Ref: 3D-NF16548

    1g
    1.920,00€
    50mg
    303,00€
    100mg
    403,00€
    250mg
    651,00€
    500mg
    1.051,00€
  • 2-Methylthio-N6-methyladenosine

    CAS :
    <p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>
    Formule :C12H17N5O4S
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :327.36 g/mol

    Ref: 3D-NM159489

    5mg
    731,00€
    10mg
    866,00€
    25mg
    1.334,00€
  • 2,5'-Anhydro-thymidine

    CAS :
    <p>2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.</p>
    Formule :C10H12N2O4
    Degré de pureté :Min. 95%
    Masse moléculaire :224.21 g/mol

    Ref: 3D-NA02980

    1g
    2.440,00€
  • 2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite


    <p>2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization.<br>This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.</p>
    Formule :C49H59N6O9P
    Degré de pureté :Min. 95%
    Masse moléculaire :907.03 g/mol

    Ref: 3D-PD09146

    1g
    478,00€
    2g
    883,00€
    250mg
    304,00€
    500mg
    308,00€
  • 8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine

    CAS :
    <p>8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.</p>
    Formule :C34H35BrN6O6
    Degré de pureté :Min. 95%
    Masse moléculaire :703.6 g/mol

    Ref: 3D-EIA58253

    500mg
    1.008,00€
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

    CAS :
    <p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB15553

    2g
    718,00€
    5g
    1.284,00€
    10g
    2.013,00€
    25g
    4.269,00€
  • 2-Fluoroinosine

    CAS :
    <p>2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis.<br>2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug has</p>
    Formule :C10H11FN4O5
    Degré de pureté :Min. 95%
    Masse moléculaire :286.22 g/mol

    Ref: 3D-NF17964

    2mg
    303,00€
    5mg
    358,00€
    10mg
    579,00€
    25mg
    999,00€
    50mg
    1.710,00€
  • 5'-Amino-2',5'-dideoxyuridine

    CAS :
    <p>5'-Amino-2',5'-dideoxyuridine (5-ADU) is a pyrimidine nucleoside that is structurally similar to thymidylate, which it inhibits. 5-ADU is used in the treatment of viral infections and cancers, as well as in the prevention of radiation injury. It has been shown to be an effective antiviral agent against herpes virus and some DNA viruses, such as adenovirus, vaccinia virus, and poliovirus. 5-ADU also enhances the effects of azauridine and other pyrimidine nucleosides in bacterial enzymes such as E. coli. 5-ADU has not been shown to be active against uninfected cells or tissues.</p>
    Formule :C9H13N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :227.22 g/mol

    Ref: 3D-NA163153

    10mg
    303,00€
    25mg
    394,00€
    50mg
    491,00€
    100mg
    701,00€
    250mg
    999,00€
  • 2-Methanesulfonyl-pyrimidine

    CAS :
    <p>2-Methanesulfonyl-pyrimidine is a thiourea that is used as a catalyst in organic synthesis. It can be prepared by reacting phosphorus oxychloride with malonate and hydrochloric acid at temperatures of about 0°C to 150°C. The chloride anion is replaced by the sulfonyl chloride, which has high affinity for the 2-position of thiourea. This reaction leads to an intermediate that can be hydrolyzed with hydrochloric acid to produce 2-methanesulfonyl-pyrimidine. 2-Methanesulfonyl-pyrimidine is soluble in water and can be used as a catalyst in wastewater treatment processes, such as cyclic oxidation or oxychlorination reactions.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NM44273

    1g
    363,00€
    2g
    526,00€
    5g
    793,00€
    500mg
    300,00€
  • 2'-Deoxy-N6,N6-dimethyladenosine


    <p>2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND159727

    100mg
    5.124,00€
  • 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-β-D-ribofuranosyl)purine

    CAS :
    <p>2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is an antiviral agent that inhibits the replication of the viral DNA by binding to the viral DNA and preventing its transcription into RNA. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a modified nucleoside that can be used in various areas of research, including antiviral and anticancer activities.</p>
    Formule :C10H15N7O2
    Degré de pureté :Min. 95%
    Masse moléculaire :265.28 g/mol

    Ref: 3D-ND05219

    1g
    486,00€
    2g
    863,00€
    5g
    1.085,00€
    10g
    1.898,00€
  • 2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine


    <p>2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA158766

    5g
    303,00€
    10g
    319,00€
  • 2-Methylthio-6-chloropurine

    CAS :
    <p>2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.</p>
    Formule :C6H5CIN4S
    Degré de pureté :Min. 95%
    Masse moléculaire :304.11 g/mol

    Ref: 3D-NM29024

    1g
    1.303,00€
    2g
    2.318,00€
    5g
    4.757,00€
  • 2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine

    CAS :
    <p>2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.</p>
    Formule :C19H20N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :388.37 g/mol

    Ref: 3D-NA31581

    1g
    3.055,00€
    100mg
    797,00€
    250mg
    1.254,00€
    500mg
    1.883,00€
  • 5'-O-DMT-N2-phenylacetylguanosine

    CAS :
    <p>5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.</p>
    Formule :C39H37N5O8
    Degré de pureté :Min. 95%
    Masse moléculaire :703.76 g/mol

    Ref: 3D-ND08925

    1g
    430,00€
    2g
    707,00€
    5g
    1.480,00€
  • Adenosine-5'-carboxylic acid

    CAS :
    <p>Adenosine-5'-carboxylic acid is a pharmaceutical compound that is used as an anti-inflammatory agent. It is a synthetic, non-nucleoside adenine nucleotide analog that has been shown to have potent anti-inflammatory activity in vitro. Adenosine-5'-carboxylic acid inhibits the synthesis of prostaglandins and leukotrienes which are mediators of inflammation. It also inhibits the synthesis of protein kinase C, which plays a role in cell proliferation, differentiation and apoptosis. Adenosine-5'-carboxylic acid has also been found to inhibit the growth of glioma cells in tissue culture and human muscle cells in vivo. The mechanism for this effect may be due to its ability to inhibit DNA synthesis and induce apoptosis.</p>
    Formule :C10H11N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :281.23 g/mol

    Ref: 3D-NA158444

    1g
    1.558,00€
    2g
    1.878,00€
    5g
    2.442,00€
    10g
    3.741,00€
    500mg
    1.062,00€
  • 2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine


    <p>2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a novel ribonucleoside that has been synthesized as a phosphoramidite. It is an anticancer agent with antiviral and antiretroviral properties. The 2,5'-Anhydro-5,6-didehydro-2'-deoxy-2',2'-difluorouridine is a modified nucleoside that has the potential to be used in the treatment of certain cancers. It can also be used to inhibit viral replication by inhibiting RNA synthesis. This compound inhibits the enzyme diphosphate kinase, which converts ATP into ADP and phosphate. This leads to an accumulation of ADP in cells and inhibition of DNA synthesis.</p>
    Formule :C9H10F2N2O5
    Degré de pureté :Min. 95%
    Masse moléculaire :264.18 g/mol

    Ref: 3D-NA71416

    10mg
    3.660,00€
  • 5'-O-DMT-2'-fluoro-2'-deoxyinosine

    CAS :
    <p>5'-O-DMT-2'-fluoro-2'-deoxyinosine is a novel nucleoside that has been modified with 2'-fluoro and 2'-deoxy substitutions. It is phosphoramidite, which can be activated by any of the standard methods to make DNA or RNA. 5'-O-DMT-2'-fluoro-2'-deoxyinosine is synthesized from DMT and fluoroacetyl chloride in the presence of triethylamine. This nucleoside has antiviral activity against HIV and influenza A virus, as well as anticancer effects.</p>
    Formule :C31H29FN4O6
    Degré de pureté :Min. 95%
    Masse moléculaire :572.58 g/mol

    Ref: 3D-ND46158

    100mg
    303,00€
    250mg
    396,00€
    500mg
    562,00€
  • Adenosine 5'-monophosphate [U-13C10,U-15N5]

    CAS :
    <p>Adenosine 5'-monophosphate (AMP) is a nucleoside that is used in the synthesis of DNA, RNA and other nucleic acids. AMP is also an antiviral and anticancer agent that can be used to activate other drugs. AMP is synthesized from adenosine triphosphate (ATP) by removing one phosphate group, resulting in the formation of adenosine diphosphate (ADP). ADP can then be converted to AMP by adding a phosphate group back on. This synthetic process can be modified to produce novel derivatives of AMP with enhanced properties.</p>
    Formule :C10H14N5O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :362.11 g/mol

    Ref: 3D-NA31536

    5mg
    1.503,00€
    10mg
    2.196,00€
    25mg
    4.574,00€
  • 2',3'-O-Isopropylidene-6-thioinosine

    CAS :
    <p>2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.<br>2',3'-O-Isopropylidene-6-thioinos</p>
    Formule :C13H16N4O4S
    Degré de pureté :Min. 95%
    Masse moléculaire :324.36 g/mol

    Ref: 3D-NI08025

    10g
    1.952,00€
    25g
    2.746,00€
    50g
    3.802,00€
  • 3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt


    <p>3'-O-Azidomethyl 2'-deoxyguanosine 5'-O-triphosphate sodium salt is an antiviral and anticancer agent used in the treatment of HIV, hepatitis B, hepatitis C, herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein-Barr virus, and Kaposi's sarcoma. It is a nucleotide analog that inhibits viral replication by inhibiting DNA synthesis. The phosphate group on this compound is modified with an azide group to inhibit deamination by phosphodiesterases. This product has been shown to be effective against leukemia cells.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA46070

    1mg
    1.952,00€
    2mg
    3.660,00€
  • Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt

    CAS :
    <p>Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.</p>
    Formule :C20H26N7O10P·NH3
    Degré de pureté :Min. 95%
    Masse moléculaire :572.47 g/mol

    Ref: 3D-NT08058

    1mg
    303,00€
    2mg
    394,00€
    5mg
    673,00€
    10mg
    837,00€
  • Diethyl N-(tert-Butoxycarbonyl)phosphoramidate

    CAS :
    <p>Diethyl N-(tert-Butoxycarbonyl)phosphoramidate is a chemical compound that is used in coupling reactions. It has a magnetic resonance and can be used to detect the presence of certain elements. Diethyl N-(tert-Butoxycarbonyl)phosphoramidate shifts at 12.2 ppm, which is higher than the normal chemical shift for an ester of this type. The magnetic resonance data for Covid-19 pandemic, Covid-19, and 3D-19 are all constant with Covid-19 pandemic being the most intense. Covid-19 pandemic has a structural formula of C8H16O4N2S, which is different from Covid-19 and 3D-19, which have structural formulas of C8H14O4N2S. The three compounds have similar chemical shifts with covid-19 having a slightly higher frequency than covid-19 pandemic</p>
    Formule :C9H20NO5P
    Degré de pureté :Min. 95%
    Masse moléculaire :253.23 g/mol

    Ref: 3D-FD59869

    1g
    300,00€
    2g
    376,00€
    5g
    598,00€
    10g
    1.019,00€
  • 2'-Deoxy-2',2'-difluoroguanosine

    CAS :
    <p>2'-Deoxy-2',2'-difluoroguanosine (DFG) is an analog of guanosine that has been used to study the effect of guanylate kinase on cellular proliferation. This compound has also been shown to have a cytotoxic effect on leukemia cells. DFG has been shown to inhibit the growth of cancer cells and induce apoptosis in HL-60 leukemia cells. It has also been shown to inhibit the synthesis of DNA, RNA, and proteins. These effects are due to inhibition of guanylate kinase activity and may be related to its ability to cause the release of intracellular calcium ions.</p>
    Formule :C10H11F2N5O4
    Degré de pureté :Min. 95%
    Masse moléculaire :303.22 g/mol

    Ref: 3D-ND158376

    1g
    5.123,00€
  • N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite


    <p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is a monophosphate nucleoside that is synthetically modified. It has anticancer activity and can be used to treat viral infections. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is also a novel nucleoside that exhibits antiviral and antitumor properties. This compound can be used as an intermediate in the synthesis of DNA, ribonucleosides, and deoxyribonucleosides.</p>
    Formule :C39H49N4O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :716.8 g/mol

    Ref: 3D-PA63538

    25mg
    303,00€
    50mg
    394,00€
    100mg
    561,00€
  • 5-Bromo-2-(2-methoxyethylamino)pyrimidine

    CAS :
    <p>5-Bromo-2-(2-methoxyethylamino)pyrimidine is a novel, ribonucleoside that exhibits anticancer activity. It inhibits DNA synthesis and viral replication by binding to the ribonucleotide reductase enzyme. 5-Bromo-2-(2-methoxyethylamino)pyrimidine is synthesized from phosphoramidites and has been shown to have antiviral and antifungal activities. The drug inhibits the enzyme's activity by mimicking natural nucleosides and monophosphates. It is also modified with an amino group to increase its stability against chemical degradation.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB44319

    1g
    314,00€
    5g
    994,00€
    500mg
    303,00€
  • 2',3'-Dideoxyuridine-5'-O-monothiophosphate

    CAS :
    <p>2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.</p>
    Formule :C9H13N2O6PS
    Degré de pureté :Min. 95%
    Masse moléculaire :308.25 g/mol

    Ref: 3D-ND10394

    1µg
    303,00€
    5µg
    497,00€
    10µg
    736,00€
  • 3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester

    Produit contrôlé

    <p>3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.</p>
    Formule :C23H26D3N5O13
    Degré de pureté :Min. 95%
    Masse moléculaire :586.52 g/mol

    Ref: 3D-NA04579

    1mg
    455,00€
    2mg
    712,00€
    5mg
    1.480,00€
    10mg
    2.498,00€
  • 3-Deazaguanosine

    CAS :
    <p>3-Deazaguanosine is a nucleotide that is found in uridine, which is present in the nucleic acids of all cells. It has been shown to be cytotoxic to colorectal adenocarcinoma and carcinoma cell lines, and this cytotoxicity may be due to its ability to inhibit energy metabolism. 3-Deazaguanosine has also been shown to significantly inhibit viral replication, including HIV and herpes simplex virus type 1. It binds with high affinity to monoclonal antibodies that are specific for nucleotide levels. 3-Deazaguanosine inhibits tissue culture enzyme activity and can cause significant changes in adenine nucleotide levels in cell culture.</p>
    Formule :C11H14N4O5
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :282.25 g/mol

    Ref: 3D-ND30048

    1g
    2.013,00€
    2g
    3.172,00€
    250mg
    930,00€
    500mg
    1.378,00€
  • dATP - 100 mmol solution

    CAS :
    <p>aATP is useful in molecular biology applications including PCR/qPCR, reverse transcription, DNA labelling and DNA sequencing.</p>
    Formule :C10H16N5O12P3
    Degré de pureté :Min. 95%
    Masse moléculaire :491.18 g/mol

    Ref: 3D-ND46290

    50mg
    291,00€
  • 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1)

    CAS :
    <p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>
    Formule :C31H33N2O9P
    Degré de pureté :Min. 95%
    Masse moléculaire :608.58 g/mol

    Ref: 3D-NT158343

    1g
    2.135,00€
  • 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one

    CAS :
    <p>1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one is a nucleoside that has been modified to have anticancer properties. The drug is an activator of the enzyme ribonucleotide reductase, which is responsible for making deoxyribonucleotides from ribonuclesides. 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one inhibits viral replication by inhibiting the activity of DNA polymerase and preventing RNA synthesis. This drug also inhibits human immunodeficiency virus type 1 (HIV) reverse transcriptase and is used as an antiviral agent.</p>
    Formule :C10H12N2O7
    Degré de pureté :Min. 95%
    Masse moléculaire :272.21 g/mol

    Ref: 3D-NR04848

    1g
    1.974,00€
    50mg
    353,00€
    100mg
    516,00€
    250mg
    906,00€
    500mg
    1.446,00€
  • 3'-Epi gemcitabine

    CAS :
    <p>3'-Epi-GEMCITABINE is a nucleoside phosphoramidite that is used in the synthesis of DNA and RNA. It is an antiviral agent and also has anticancer activity. 3'-Epi-GEMCITABINE inhibits the growth of cells by inhibiting DNA synthesis, which leads to cell death. The chemical name for 3'-epigemcitabine is 2',3'-dideoxyinosine monophosphate. 3'-Epi-GEMCITABINE can be synthesized from 2',3'-dideoxyinosine monophosphate and 5-bromo-2'-deoxyuridine diphosphate.</p>
    Formule :C9H11F2N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :263.2 g/mol

    Ref: 3D-NE22706

    1mg
    1.331,00€
    2mg
    1.994,00€
    5mg
    3.834,00€
  • Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution


    <p>Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.</p>
    Formule :C22H34N5O17P3S·xLi
    Degré de pureté :Min. 95%
    Masse moléculaire :765.52 g/mol

    Ref: 3D-NB32054

    1g
    2.440,00€
  • 5'-O-DMT-2'-O-(2-methoxyethyl)uridine

    CAS :
    <p>5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.</p>
    Formule :C33H36N2O9
    Degré de pureté :Min. 95%
    Masse moléculaire :604.65 g/mol

    Ref: 3D-ND76851

    50g
    3.335,00€
  • 5-Azauridine

    CAS :
    <p>5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.</p>
    Formule :C8H11N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :245.19 g/mol

    Ref: 3D-NA145615

    100mg
    1.629,00€
  • N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite


    <p>N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have anticancer effects in vitro and in vivo by inducing apoptosis and cell cycle arrest. This compound has also been shown to be more potent than other nucleosides, such as cytidine 5'-diphosphate (CDP) or cytidine 5'-monophosphate (CMP). This chemical is not yet commercially available but can be custom synthesized for research purposes.</p>
    Formule :C52H64N5O10P
    Degré de pureté :Min. 95%
    Masse moléculaire :950.07 g/mol

    Ref: 3D-PB63476

    1g
    329,00€
    2g
    478,00€
    5g
    962,00€
    10g
    1.494,00€
    500mg
    300,00€
  • 2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite

    Produit contrôlé
    CAS :
    <p>2'-Deoxy-5'-O-FDMT-N2-isobutyryl-guanosine 3'-CE phosphoramidite is a modified nucleoside that is used as an antiviral agent. It is synthesized by modifying the 2'-deoxyribose sugar with a 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N2-isobutyrylguanosine 3' phosphate. This compound has shown anticancer activity in vitro and has been studied in animal models. The synthesis of this compound can be accomplished through the use of diphosphate, which gives it an advantage over natural nucleosides because it does not require ribonucleotides.</p>
    Formule :C54H57F17N7O8P
    Degré de pureté :Min. 95%
    Masse moléculaire :1,286.02 g/mol

    Ref: 3D-PD11330

    250mg
    304,00€
    500mg
    457,00€
  • N4-Acetyl-3'-O-acetyl-2'-deoxycytidine

    CAS :
    <p>N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is a novel, modified nucleoside that contains a phosphoramidate linkage. It has been shown to have anticancer and antiviral properties. N4-Acetyl-3'-O-acetyl-2'-deoxycytidine is also an activator of the immune system and has been shown to be effective against HIV.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA03451

    1g
    1.002,00€
    2g
    1.353,00€
    5g
    1.691,00€
    10g
    1.954,00€
  • 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid

    CAS :
    <p>4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid is a novel monophosphate and nucleotide analogue, which can activate the HIV reverse transcriptase. It has been shown to be cytotoxic to cancer cells in vitro. 4-(difluoromethyl)-2-hydroxy-pyrimidine-5-carboxylic acid has been used for the synthesis of phosphoramidites and DNA and RNA analogues.</p>
    Formule :C6H4F2N2O3
    Degré de pureté :Min. 95%
    Masse moléculaire :190.1 g/mol

    Ref: 3D-ND59458

    50mg
    303,00€
    100mg
    349,00€
    250mg
    621,00€
  • 2-Chloropyrimidine-4-carboxamide

    CAS :
    <p>2-Chloropyrimidine-4-carboxamide is an activator that is a novel chemical entity of deoxyribonucleosides, phosphoramidites, ribonuclesides, and antiviral nucleosides. It has been shown to have high purity and quality. 2-Chloropyrimidine-4-carboxamide has been used in the synthesis of oligodeoxynucleotides for antiviral activity.</p>
    Formule :C5H4ClN3O
    Degré de pureté :Min. 95%
    Masse moléculaire :157.56 g/mol

    Ref: 3D-NC57418

    1g
    478,00€
    2g
    725,00€
    500mg
    300,00€
  • O6-Benzyl-N2,3-etheno guanosine

    CAS :
    <p>O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.</p>
    Formule :C19H19N5O5
    Degré de pureté :Min. 95%
    Masse moléculaire :397.38 g/mol

    Ref: 3D-NB16629

    5mg
    303,00€
    10mg
    401,00€
    25mg
    650,00€
    50mg
    1.055,00€
    100mg
    1.916,00€
  • Guanosine 5'-[β,γ-imido]triphosphate tetralithium hydrate

    CAS :
    <p>Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate (GTP) is a nucleotide that is synthesized from guanosine 5'-diphosphate. GTP is an effector molecule that regulates the cytosolic protein synthesis and transport pathways. It binds to a number of proteins, including the guanine nucleotide-binding protein, which regulates the metabolic processes in cells. GTP has been shown to be beneficial in treating cancer by inducing apoptosis and inhibiting tumor growth. In addition, Guanosine 5'-[beta,gamma-imido]triphosphate tetralithium hydrate has been shown to inhibit congestive heart failure by reducing free radical production and increasing intracellular adenosine levels.</p>
    Formule :C10H13Li4N6O13P3
    Degré de pureté :Min. 95%
    Masse moléculaire :546 g/mol

    Ref: 3D-PCA56403

    25mg
    857,00€
    50mg
    1.293,00€
    100mg
    2.014,00€
  • Thymidine-3',5'-tetrabenzyldiphosphate


    <p>Thymidine-3',5'-tetrabenzyldiphosphate is a monophosphate analog of thymidine. It has been used as a building block for the synthesis of DNA, RNA, and phosphoramidites. Thymidine-3',5'-tetrabenzyldiphosphate is a novel nucleoside compound that has been shown to have anticancer and antiviral activities. This product is intended for research purposes only.</p>
    Formule :C38H40N2O11P2
    Degré de pureté :Min. 95%
    Masse moléculaire :762.68 g/mol

    Ref: 3D-NT07361

    5mg
    303,00€
    10mg
    309,00€
    25mg
    589,00€
    50mg
    1.013,00€
    100mg
    1.710,00€
  • 7-Deaza-2-mercaptohypoxanthine

    CAS :
    <p>7-Deaza-2-mercaptohypoxanthine is a nucleoside that has been found to have anticancer activity in vivo. It has also been shown to inhibit the replication of HIV and herpes simplex virus. 7-Deaza-2-mercaptohypoxanthine is an analog of hypoxanthine, which is a nucleoside that can be found in DNA and RNA. In addition, this compound can be used as a phosphoramidite or nucleotide analogue for the synthesis of DNA and RNA. This compound can also be used as an antiviral agent against herpes simplex virus type 1 (HSV1).</p>
    Formule :C6H5N3OS
    Degré de pureté :Min. 95%
    Masse moléculaire :167.19 g/mol

    Ref: 3D-ND10405

    1g
    598,00€
    250mg
    304,00€
    500mg
    416,00€