Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.Formule :C24H20N8O4Degré de pureté :Min. 95%Masse moléculaire :484.47 g/mol1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine
CAS :Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.Formule :C35H31N3O9SDegré de pureté :Min. 95%Masse moléculaire :669.7 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate
2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.
Formule :C10H17ClN5O12P3Degré de pureté :Min. 95%Masse moléculaire :527.64 g/molN4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate
N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.Degré de pureté :Min. 95%3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine
CAS :3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.Formule :C21H23N5O6Degré de pureté :Min. 95%Masse moléculaire :441.44 g/molAdenosine 5'-triphosphate trisodium salt
CAS :ATP is an important molecule in the body that is involved in a number of cellular processes, including energy production and transmission. It has been shown to be tumorigenic and is found at high levels in plasma membranes and muscle cells. ATP binds to the adenylate cyclase enzyme in the cell membrane and stimulates its activity, which increases intracellular levels of cyclic AMP (cAMP). Cyclic AMP activates protein kinase A, which phosphorylates proteins, leading to a cascade of reactions that result in cellular changes. ATP also has pharmacological effects on the plasma membrane by increasing its permeability to certain ions such as potassium ions. This leads to an increase in the rate of depolarization of the cell membrane, which causes an influx of calcium ions into the cell.Formule :C10H15N5O13P3Na3Degré de pureté :Min. 95%Masse moléculaire :575.14 g/molN6-Benzyladenosine 5'-triphosphate triethylammonium salt
CAS :N6-Benzyladenosine 5'-triphosphate triethylammonium salt is a hydrogen bond donor that is not naturally occurring. It has been shown to be a potent and selective analog of ATP with high specificity for cGMP-dependent protein kinase. This drug has been used to study the function of serotonin receptors, tyrosine kinases, and epidermal growth factor receptors. N6-Benzyladenosine 5'-triphosphate triethylammonium salt has also been shown to increase the sensitivity of cells to epidermal growth factor and to inhibit the reuptake of serotonin.END>Formule :C19H26N5O11P3·C18H48N3Degré de pureté :Min. 95%Masse moléculaire :899.95 g/mol3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may beFormule :C10H16N5O13P3·xLiDegré de pureté :Min. 95%Couleur et forme :Colorless Clear LiquidMasse moléculaire :507.18 g/mol3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine
3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.Formule :C28H33FN2O6SiDegré de pureté :Min. 95%Masse moléculaire :540.66 g/mol2-Methylthioadenosine-5'-triphosphate
CAS :2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.Formule :C11H18N5O13P3SDegré de pureté :Min. 95%Masse moléculaire :553.27 g/molFluorescein-5(6)-carboxamidocaproyl-(5-[3-aminoallyl]uridine 5'-triphosphate) - 1 mM aqueous solution
CAS :Fluorescein-5(6)-carboxamidocaproyl-(5-[3-aminoallyl]uridine 5'-triphosphate) is a novel antiviral compound that is an activator of ribonucleoside and deoxyribonucleoside phosphorylation. It has been shown to selectively inhibit the proliferation of cancer cells, and to be cytotoxic to human leukemia cells in vitro. The compound is also able to inhibit HIV replication in vitro. Fluorescein-5(6)-carboxamidocaproyl-(5-[3-aminoallyl]uridine 5'-triphosphate) - 1 mM aqueous solution is a high purity product with CAS No. 134367-01-4 that can be used as a synthetically modified DNA or RNA building block for the production of phosphoramidites. This product has been shown to be cytotoxic against human leukemia cells in
Formule :C39H41N4O22P3Degré de pureté :Min. 95%Masse moléculaire :1,010.68 g/mol5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral drug that has been shown to inhibit the synthesis of viral RNA by inhibiting the activity of DNA polymerase. It is a novel antiviral drug with high purity and can be used for cancer treatment as well. 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also has a novel mechanism of action, which is different from other antiviral drugs such as ribonucleosides or deoxyribonucleosides. This compound is used in the synthesis of phosphoramidites for oligonucleotide synthesis.Formule :C17H27IN4O3SiDegré de pureté :Min. 95%Masse moléculaire :490.41 g/mol2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt
CAS :2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt (ddI-TP) is a nucleoside analog that inhibits HIV replication by competing with natural nucleosides for binding to HIV reverse transcriptase. ddI-TP acts as an inhibitor of human mitochondrial DNA polymerase γ, and blocks the synthesis of fatty acids in mouse cells. It is also able to inhibit signal pathways involving protein kinases and phosphatases. ddI-TP has been shown to be effective against hiv infection in mice. This drug can be used in the treatment of hiv infection, as well as in the prevention of its transmission from mother to child during pregnancy and breastfeeding.Formule :C10H15N4O12P3Degré de pureté :Min. 95%Masse moléculaire :476.17 g/mol5'-o-(Dimethoxytrityl)-N2-(dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine
CAS :Please enquire for more information about 5'-o-(Dimethoxytrityl)-N2-(dimethylaminomethylidene)-7-deaza-2'-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormule :C35H37N5O6Degré de pureté :Min. 95%Masse moléculaire :623.7 g/molCerebrosides (brain)
CAS :Cerebrosides are a group of natural and synthetic phospholipids that are found in the brain. They are made from glycerophosphoric acid and sphingosine. Cerebrosides have been shown to be anticancer agents, and may also inhibit the growth of bacteria. They can also promote DNA synthesis and prevent the destruction of DNA by inhibiting some enzymes, such as phosphodiesterase. Cerebrosides are also used to synthesize nucleosides and deoxyribonucleosides, which is important for cell division.Formule :C48H93NO8Degré de pureté :Min. 95%Masse moléculaire :812.25 g/mol5'-O-DMT-thymidine-3'-O-succinic acid
CAS :5'-O-DMT-thymidine-3'-O-succinic acid (5'-DMT-TSA) is a novel modified nucleoside that is synthesized by the activation of 5'-DMT-thymidine with succinic anhydride. 5'-DMT-TSA has been shown to be a potent inhibitor of viral replication and has anti-tumor properties. This compound has high purity, high quality, and good solubility in water. It also has a CAS number of 74405-40-6.
Formule :C35H36N2O10Degré de pureté :Min. 95%Masse moléculaire :644.67 g/mol2'-Deoxy-2'-fluoroguanosine-5'-monophosphate
CAS :2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a phosphoramidite monoester with a diphosphate group that has been synthetically modified to provide antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits the proliferation of tumor cells by interfering with DNA replication. The compound is also used as a precursor for the synthesis of 2'-deoxy-2'-fluoroguanosine, which has potent anti-HIV activity.Formule :C10H13FN5O7PDegré de pureté :Min. 95%Masse moléculaire :365.21 g/mol2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine
CAS :2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine is a monophosphate nucleoside analog that has antiviral activity against the Herpes virus. It is a cytosine analog that is incorporated into DNA and inhibits viral replication. 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine has also been shown to have anticancer properties and high purity. This compound is synthesized by the reaction of 2'-deoxycytidine and 4-(2,2,2,-trimethylpropionyl)-1,3-butanediol with O-(7-azabenzotriazol-1-yl) N,N,N',N' tetramethyluronium hexafluorophosphate (HATU) in anhydrous pyridine. The CAS number for this compound is 10089862.Formule :C34H37N3O7Degré de pureté :Min. 95%Masse moléculaire :599.69 g/molXTT, sodium salt
CAS :XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.Formule :C22H16N7NaO13S2Masse moléculaire :673.53 g/molRef: 3D-X-5000
1gÀ demander100mgÀ demander250mgÀ demander500mgÀ demander2500mgÀ demander-Unit-ggÀ demander2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
CAS :2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine is a novel modified nucleoside with antiviral activity. It has been shown to inhibit the replication of the influenza A virus in cell culture and animal models. 2′Amino-6′chloro 9-(2′deoxy 3′,5′di O′benzoyl 2′fluoro b D arabinofuranosyl)purine is an analog of adenosine that has shown anticancer activity in vitro and in vivo. It inhibits DNA synthesis by inhibiting deoxyribonucleotide synthesis and ribonucleotide synthesis. This drug also inhibits cell proliferation and induces apoptosis.Formule :C24H19ClFN5O5Degré de pureté :Min. 95%Masse moléculaire :511.89 g/mol
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