Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine is a novel antiviral drug that has been synthesized for the treatment of cancer and viral infections. This compound has been modified to increase its antiviral activity, which is due to its ability to inhibit DNA synthesis. The antiviral activity of N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine was shown in vitro using human and mouse cells infected with herpes simplex virus (HSV) type 1 and 2.Degré de pureté :Min. 95%3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine
CAS :3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a novel antiviral drug with anticancer activity. It is an inhibitor of the enzyme ribonucleotide reductase and has been shown to inhibit the production of deoxyribonucleosides in tumor cells. It also inhibits DNA synthesis by inhibiting DNA polymerase. 3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a high purity product that is available in both monophosphate and diphosphate forms.Formule :C6H4IN3ODegré de pureté :Min. 95%Masse moléculaire :261.02 g/mol5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite
5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite is an antiviral agent that has been shown to inhibit the replication of HIV in cell culture and to prevent the synthesis of the virus. 5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite inhibits viral replication by acting as a competitive inhibitor of HIV reverse transcriptase and blocking viral DNA synthesis from viral RNA. It has also been shown to have anticancer properties, which may be due to its ability to suppress tumor growth through inhibition of protein synthesis.
Degré de pureté :Min. 95%Adenosine 2',3'-cyclic monophosphate-5'-monophosphate
Adenosine 2',3'-cyclic monophosphate-5'-monophosphate (AMP-CP) is a nucleotide that is the cyclic form of adenosine monophosphate. It is a modified nucleoside that is used in the synthesis of DNA and RNA, as well as in anticancer and antiviral research. The structure of AMP-CP consists of an adenosine base attached to ribose through a phosphate group at the 3' carbon position. This nucleotide can be converted to adenosine 5'-monophosphate (AMP) by phosphoramidites, which are chemical compounds consisting of an aminopropyl group joined to a phosphoryl group. AMP-CP is also known as diphosphate or deoxyribonucleosides. AMP-CP has shown antiviral activity against herpes simplex virus type 1, HIV, influenza A virus, and vesicular stomDegré de pureté :Min. 95%5-Iodo-2’-O-methylcytidine
CAS :5-Iodo-2’-O-methylcytidine is a nucleoside that is used as an activator for the synthesis of ribonucleosides. It is also used in the synthesis of DNA, RNA, and phosphoramidites. 5-Iodo-2’-O-methylcytidine has shown anticancer activity against a variety of cancer cell lines. This novel nucleotide exhibits high quality and purity, with an excellent yield and low impurities. The compound has been assigned CAS No. 847650-69-5 and its physical properties have been described in detail.
Formule :C10H14IN3O5Degré de pureté :Min. 95%Masse moléculaire :383.14 g/molN-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS :N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine is a novel nucleoside analog which has been modified to improve its anticancer activity. This compound is an activator of adenosine deaminase and inhibits the proliferation of various tumor cells. It also blocks the formation of DNA by inhibiting the synthesis of ribonucleotides. N-acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine has antiviral properties and can inhibit HIV replication in vitro.Formule :C23H41N3O7Si2Degré de pureté :Min. 95%Masse moléculaire :527.76 g/mol4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid
CAS :4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a novel nucleoside analog that has been shown to have anticancer activity. It has also been found to have antiviral and antitumor activities. 4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a nucleoside analog that is synthesized from monophosphate, diphosphate, and phosphate esters of 2-(methylthio)pyrimidine 5'-carboxylic acid. It is an analogue of the natural nucleoside uridine and has phosphorylase enzyme activity. This agent is cytotoxic against cells in culture by inhibiting DNA synthesis.Formule :C18H22N4O2SDegré de pureté :Min. 95%Masse moléculaire :358.46 g/molN4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine-3'-CE phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-levulinoylcytidine-3'-CE phosphoramidite is a novel nucleoside analogue that is synthesized by coupling the 5'-O-levulinoyl group to the 3'-OH of cytidine. The compound has antiviral and anticancer activity, as well as potential for use in gene therapy. It is synthesized from commercially available deoxyribonucleosides, an activator, and a diphosphate. The product is purified to high purity and quality, with dsDNA conversion yields of more than 90%.Formule :C30H40N5O8PDegré de pureté :Min. 95%Masse moléculaire :629.64 g/mol9-(b-D-Arabinofuranosyl)-N6-benzoyladenine
CAS :9-(b-D-arabinofuranosyl)-N6-benzoyladenine is a novel nucleoside analogue that has been shown to be an effective anticancer agent. It is structurally related to the natural nucleosides adenosine and guanosine, but with the addition of a benzoyl group on the 9 position. This compound is also active against HIV, influenza A virus and herpes simplex virus type 1 (HSV1). It can be used as an antiviral agent in cancer therapy due to its ability to inhibit viral replication. 9-(b-D-arabinofuranosyl)-N6-benzoyladenine inhibits the growth of tumor cells by inhibiting DNA synthesis and RNA transcription. It also binds to DNA, thereby preventing DNA synthesis and RNA transcription.
Formule :C17H17N5O5Degré de pureté :Min. 95%Masse moléculaire :371.35 g/mol3'-Azido-3'-deoxythymidine methyl-D3
Produit contrôlé3'-Azido-3'-deoxythymidine methyl-D3 is a novel synthetic nucleoside. It is a modified version of the natural nucleoside deoxyribonucleoside, which is an essential component of DNA and RNA. 3'-Azido-3'-deoxythymidine methyl-D3 is an activator of the antiviral and anticancer properties of other drugs. It can be used as a phosphate donor in phosphoramidite synthesis to produce oligonucleotides for use in PCR amplification or in protein synthesis. 3'-Azido-3'-deoxythymidine methyl-D3 is also used as an antiviral agent because it inhibits viral replication by inhibiting viral reverse transcriptase.Formule :C10H10D3N5O4Degré de pureté :Min. 95%Masse moléculaire :270.26 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is an antiviral, anticancer and nucleoside phosphoramidite. It is a novel DNA building block with antiviral activity against HIV and Hepatitis C. The synthesis of N4-acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is based on the reaction of cytosine monophosphate with 2,4,6,-trimethoxybenzoyl chloride. This compound has also been shown to inhibit the proliferation of leukemia cells in vitro and has potential as a chemotherapeutic agent for cancer treatment.Formule :C43H54N5O9PDegré de pureté :Min. 95%Masse moléculaire :815.89 g/mol5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine
5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, also known as 5'-O-(4,4'-dimethoxytrityl)-N4-isobutyryl-2'-O-methyl-5-methylcytidine, is a nucleoside and nucleotide analog. It is an antiviral agent with anticancer activity. This compound has been shown to be highly active against herpes simplex virus type 1 (HSV1) in vitro. The mechanism of action is not yet fully understood but may involve modification of the viral DNA polymerase.Formule :C36H41N3O8Degré de pureté :Min. 95%Masse moléculaire :643.73 g/mol5'-Tosyl-2'-deoxycytidine
CAS :5'-Tosyl-2'-deoxycytidine is a nucleoside with anticancer activity and is a novel derivative of cytidine. It has been shown to inhibit the proliferation of human cancer cells in culture. 5'-Tosyl-2'-deoxycytidine is also an antiviral agent that inhibits the synthesis of viral DNA by inhibiting the enzyme RNA polymerase. This product is synthetic, water soluble, and stable at pH 2.0 to 10.5, making it suitable for use in pharmaceutical formulations. The purity of this product is high and its chemical structure has been modified from cytidine to increase its stability against degradation by intracellular phosphatases.Formule :C16H19N3O5SDegré de pureté :Min. 95%Masse moléculaire :365.41 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-CE phosphoramidite is a nucleoside that was synthesized by the reaction of 2'-O-tert-butyldimethylsilyl-5'-O-dimethoxytritylguanosine 3'-CE with 4-isopropylphenoxyacetic acid. This nucleoside has antiviral and anticancer activities. It has been shown to inhibit the growth of human leukemia cells in culture, and also inhibits the replication of human immunodeficiency virus (HIV).Formule :C57H74N7O10PSiDegré de pureté :Min. 95%Masse moléculaire :1,076.33 g/mol4'-C-Fluoroadenosine 5'-sulfamate
CAS :4'-C-Fluoroadenosine 5'-sulfamate is a molecule that inhibits protein synthesis by binding to the ribosomes of bacteria. It also has anti-angiogenic effects and can be used as an antimicrobial agent against staphylococci, streptococci, and mycobacteria. 4'-C-Fluoroadenosine 5'-sulfamate has minimal toxicity in humans and is not active against Saccharomyces cerevisiae or Escherichia coli. The optimum concentration for inhibiting protein synthesis in vitro was determined to be between 100 and 500 μM. This compound is inexpensive and can be synthesized from commercially available starting materials. In cell culture assays, this compound showed antimicrobial activity against staphylococci, streptococci, and mycobacteria with MIC values ranging from 0.03 to 1 mM.br> 4'-C-Fluoroadenosine 5'-sFormule :C10H13FN6O6SDegré de pureté :Min. 95%Masse moléculaire :364.31 g/mol8-Methylthioadenosine
CAS :8-Methylthioadenosine is a synthetic analogue of adenosine that has been used as a biochemical stimulator. It has been shown to inhibit uptake of fatty acids and phospholipids into cells, which may be due to the inhibition of cellular ATPase. 8-Methylthioadenosine can also be used as a precursor for other molecules, such as methylation of DNA or RNA. 8-Methylthioadenosine is synthesized from linolenic acid and phosphate in a reaction catalyzed by molecular oxygen. The synthesis is stimulated by light and heat and inhibited by cyanide. Magnetic resonance spectroscopy (NMR) was used to confirm that the molecule had the correct structure.Degré de pureté :Min. 95%2,2’-Anhydro-5’-O-DMT-5-methyluridine
CAS :2,2’-Anhydro-5’-O-DMT-5-methyluridine is an anhydro nucleosideFormule :C31H30N2O7Degré de pureté :Min. 95%Masse moléculaire :542.58 g/mol(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride
CAS :(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol HCl is an activator of DNA polymerase. It is a novel modified deoxyribonucleosides and nucleosides that has antiviral, anticancer and antifungal activities. It can be used in the treatment of various diseases such as HIV, cancer and chronic hepatitis B virus infection.Formule :C11H12ClN5O•HClDegré de pureté :Min. 95%Masse moléculaire :302.16 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate
CAS :2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate is a nucleoside that is modified by the incorporation of an isobutyryl group at the 2' position. It has shown to be an activator of phosphoramidites and can be used as a precursor for the synthesis of nucleic acids, including DNA and RNA. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate has been shown to have anticancer properties, antiviral properties, and antiinflammatory properties.Formule :C39H41N5O10Degré de pureté :Min. 95%Masse moléculaire :739.77 g/molAdenosine 5'-monophosphate [U-13C10,U-15N5]
CAS :Adenosine 5'-monophosphate (AMP) is a nucleoside that is used in the synthesis of DNA, RNA and other nucleic acids. AMP is also an antiviral and anticancer agent that can be used to activate other drugs. AMP is synthesized from adenosine triphosphate (ATP) by removing one phosphate group, resulting in the formation of adenosine diphosphate (ADP). ADP can then be converted to AMP by adding a phosphate group back on. This synthetic process can be modified to produce novel derivatives of AMP with enhanced properties.Formule :C10H14N5O7PDegré de pureté :Min. 95%Masse moléculaire :362.11 g/mol
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