Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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N-Benzoyl- 5'- O- DMT- 2'- O-[( triisopropylsilyl oxy)methyl]-adenosine 3'- CE phosphoramidite
CAS :N-Benzoyl- 5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-adenosine 3'-Ce phosphoramidite (Bz-5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-Ado-3'-Ce Phosphoramidite) is a novel nucleoside phosphoramidite. It is an analogue of the natural nucleoside adenosine. This compound has been shown to be an antiviral and anticancer agent in vitro. Bz-5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-Ado-3'-Ce Phosphoramidite can also act as a DNA or RNA activator, which leads to increased levels of transcription, translation, and replication by increasing the number of ribonucleotide tri
Degré de pureté :Min. 95%1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS :Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Formule :C29H53N3O4Si3Degré de pureté :Min. 95%Masse moléculaire :592.01 g/mol2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate
CAS :2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate is a novel synthetic nucleoside analogue. It has been shown to inhibit the proliferation of cancer cells and have antiviral activity. It is phosphorylated by kinase enzymes to form 2'-bromo-2'-deoxyuridine monophosphate (BrDUMP). This compound also inhibits DNA replication, RNA transcription, and protein synthesis.Degré de pureté :Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine is a novel antiviral drug that has been synthesized for the treatment of cancer and viral infections. This compound has been modified to increase its antiviral activity, which is due to its ability to inhibit DNA synthesis. The antiviral activity of N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Sp-oxazaphospholidine was shown in vitro using human and mouse cells infected with herpes simplex virus (HSV) type 1 and 2.Degré de pureté :Min. 95%5-Fluoro-6-iodouridine
CAS :5-Fluoro-6-iodouridine is a nucleoside that is used as the starting material for synthesizing fluorinated pyrimidine derivatives, which are used in cancer treatment. 5-Fluoro-6-iodouridine is an activator of ribonucleotide reductase and can be used to inhibit the growth of tumor cells. 5-Fluoro-6-iodouridine has been shown to inhibit the proliferation of human leukemia cells in culture, with cytotoxicity that was comparable to that of 5-fluorouracil.Formule :C9H10FIN2O6Degré de pureté :Min. 95%Masse moléculaire :388.09 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is an antiviral, anticancer and nucleoside phosphoramidite. It is a novel DNA building block with antiviral activity against HIV and Hepatitis C. The synthesis of N4-acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite is based on the reaction of cytosine monophosphate with 2,4,6,-trimethoxybenzoyl chloride. This compound has also been shown to inhibit the proliferation of leukemia cells in vitro and has potential as a chemotherapeutic agent for cancer treatment.Formule :C43H54N5O9PDegré de pureté :Min. 95%Masse moléculaire :815.89 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine is a novel nucleoside that is activated with anhydrous ammonia and then converted to the corresponding 5'-O-DMT derivative. The 2'-O-tert-butyldimethylsilyl group protects the 5'-position of the sugar moiety from attack by phosphodiesterases, allowing for its use as a substrate in DNA synthesis. The ribose moiety is also modified at the 2' position, which prevents the formation of 3',5'-cyclic monophosphate (cMP) during dephosphorylation and thereby inhibits viral replication. This nucleotide analog has been shown to be active against HIV, hepatitis B virus, and influenza A virus.Degré de pureté :Min. 95%2'-Deoxy-N6,N6-dimethyladenosine
2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å
2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å is an anticancer agent that is used in the synthesis of DNA and RNA. It can be used as a monophosphate or diphosphate, and has been shown to inhibit cancer cells. 2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å is modified to have a long half life in the body. This chemical has been synthesized with high purity and quality, making it suitable for research purposes.Degré de pureté :Min. 95%N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine
CAS :N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine is a synthetic nucleoside that is used as an antiviral. It has been shown to be effective against HIV and HSV. N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine prevents the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. It also inhibits the production of deoxyribonucleotides and DNA by binding to the active site of the enzyme DNA polymerase.Formule :C30H47N3O7SSi2Degré de pureté :Min. 95%Masse moléculaire :649.95 g/mol2'-Deoxy-N2-DMF-5'-DMT-2'-fluoroguanosine
CAS :2'-Deoxy-N2-DMF-5'-DMT-2'-fluoroguanosine is an anticancer agent that has been modified to contain a 2'-deoxyribonucleoside and a 5'-dimethoxytrityl (DMT) group at the 2' position. The compound inhibits DNA synthesis by binding to the enzyme DNA polymerase, thereby preventing replication. This compound is novel because it contains a deoxyribonucleoside, which is not found in any other anticancer nucleotide analogs. It also has antiviral properties against HIV, herpes simplex virus type 1, and poliovirus.Formule :C34H35FN6O6Degré de pureté :Min. 95%Masse moléculaire :642.68 g/mol1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione
CAS :1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione is an activator that is a synthetic analogue of 5-(3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzylidene)-pyrimidine-2. This compound has antiviral and anticancer properties. It is being investigated for its ability to modify DNA in order to inhibit the synthesis of deoxyribonucleosides and ribonucleosides.Degré de pureté :Min. 95%Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS :Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an antiviral nucleoside that has been shown to inhibit HIV and HCV replication in vitro. It also inhibits the proliferation of cancer cells in vitro and induces apoptosis in vivo. Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a novel nucleoside that was designed for use as an anticancer agent. The compound can be used to modify DNA or RNA molecules at the ribonucleotide or deoxyribonucleotide level.Formule :C28H46N7O16P3SDegré de pureté :Min. 95%Masse moléculaire :861.69 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE succinate TEA salt
5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE succinate TEA salt is a novel, modified nucleoside with antiviral activity. It is synthesized from 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine and the corresponding 2',3',4,4',5,5'-hexachloroacetone adduct. This compound has been shown to be an activator of diphosphate synthesis and ribonucleotide reductase. It is also a potent inhibitor of deoxyribonucleic acid synthesis and tumor cell growth in vitro. The product has been shown to have anticancer properties in vitro and in vivo. The product is not activated by the enzyme phosphodiesterase, which means it does not cause any negative side effects such as hypertension or gastrointestinal disturbance.Degré de pureté :Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å
2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å is a nucleoside monophosphate that is chemically modified. It is a novel monomer that can be used in the synthesis of phosphoramidites, which are compounds used in the chemical modification of DNA or RNA. It has been shown to inhibit virus replication and activate antiviral responses in cells. 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å is also a high quality compound with a purity level of 99%.Degré de pureté :Min. 95%Couleur et forme :Powder1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole
CAS :1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole is an anticancer drug that has been shown to inhibit tumor growth in vivo. This drug binds to the integrin receptor, which is expressed on the surface of cells and is involved in the process of cell adhesion. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-2-nitroimidazole inhibits tumor growth by inhibiting hypoxic tumor formation. Hypoxia is a condition where there is not enough oxygen for normal cell function. This drug has also been shown to reduce inflammation, which may be due to its ability to inhibit proinflammatory cytokines, such as IL-1β and TNFα, from binding to their receptors on cells. 1-(5'-Deoxy-5'-fluoro-a-D-arabinofuranosyl)-Formule :C8H10FN3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :247.18 g/mol2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a modified nucleoside. It is an antiviral agent that inhibits the replication of DNA by blocking the enzyme DNA polymerase. 2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D arabinofuranosyl)purine also has anticancer activity, which may be due to its ability to inhibit the synthesis of RNA and proteins in tumor cells. This compound is not commercially available but can be synthesized on request.Degré de pureté :Min. 95%1-(b-D-Arabinofuranosyl)cytosine 5'-triphosphate triethyammonium salt
1-(B-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt is a novel anticancer and antiviral agent that belongs to the group of nucleosides. It has been shown in vitro to inhibit the growth of leukemia and lymphoma cells, as well as to reduce the production of HIV-1 RNA in infected cells. 1-(B-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt has also been shown to inhibit influenza virus replication at concentrations of 2x10 Molar. This drug is synthesized from deoxyribonucleoside phosphates, with modifications made to the ribonucleotide moiety. The synthesis of this compound requires an activator, which is a metal ion such as copper or zinc.Degré de pureté :Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel nucleotide analogue that inhibits the growth of cancer cells by inhibiting DNA synthesis. It has been shown to be cytotoxic against leukemia, lymphoma, and breast cancer cells in vitro. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is also an antiviral agent and can inhibit HIV replication. This product is supplied as a white solid powder and is soluble in water.
Degré de pureté :Min. 95%2'-TFA-NH-dG
CAS :2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.
Formule :C12H13F3N6O5Degré de pureté :Min. 95%Masse moléculaire :378.26 g/mol
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