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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt


    <p>1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is a novel antiviral agent that is synthesized from ribonucleosides. It is an activator of the monophosphate form of RNA polymerase and inhibits the synthesis of DNA in cells. This drug has also been shown to be effective against cancer cells and may be useful for treatment of leukemia.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NA137363

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    À demander
  • 7-Deaza-2'-deoxy-7-iodoguanosine

    CAS :
    <p>7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:</p>
    Formule :C11H13IN4O4
    Degré de pureté :Min. 97 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :392.16 g/mol

    Ref: 3D-ND02147

    1g
    669,00€
    2g
    974,00€
    5g
    1.494,00€
    250mg
    304,00€
    500mg
    477,00€
  • 2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt


    <p>2'-Deoxy-2'-fluoroadenosine 5'-a-thiotriphosphate sodium salt (2'F-ATP) is a nucleoside analog that inhibits viral DNA polymerase and induces apoptosis in cancer cells. It is a novel, modified nucleotide that can be phosphorylated to 2'F-dATP, 2'F-AMP, or 2'F-GMP. The phosphate group in 2'F-ATP is replaced by a thiophosphate group, which increases the stability of the molecule and prevents it from being hydrolyzed by phosphatases. This makes it an effective activator for DNA synthesis reactions.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND164929

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    À demander
  • 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine

    CAS :
    <p>5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.</p>
    Formule :C24H23N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :449.46 g/mol

    Ref: 3D-NA08684

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    À demander
  • 9-(2’-Deoxy-2’-fluoro-arabinofuranosyl)adenine 5’-triphosphate triethyl ammonium salt


    <p>Ai Product Descriptions 50 Creative</p>
    Degré de pureté :Min. 95%

    Ref: 3D-ND162976

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    À demander
  • 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite


    <p>2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It is synthesized from 5'-O-trityluridine and 2'-deoxyribonucleosides. This nucleoside has antiviral and anticancer properties, which are due to the fact that it inhibits viral replication by inhibiting DNA polymerase and prevents cell proliferation. 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a high purity, high quality product that can be used in DNA synthesis and cancer treatment.</p>
    Formule :C43H57N4O7PSi
    Degré de pureté :Min. 95%
    Masse moléculaire :801.02 g/mol

    Ref: 3D-PB08948

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  • 9-(b-D-Arabinofuranosyl)adenine

    CAS :
    <p>9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.</p>
    Formule :C10H13N5O4
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :267.24 g/mol

    Ref: 3D-NA06007

    50g
    276,00€
    100g
    410,00€
    250g
    729,00€
  • 3-Deazaadenosine

    CAS :
    <p>A potential role in apoptosis and cellular senescence.</p>
    Formule :C11H14N4O4
    Degré de pureté :Min. 99 Area-%
    Couleur et forme :Powder
    Masse moléculaire :266.26 g/mol

    Ref: 3D-ND04697

    1mg
    193,00€
    2mg
    345,00€
    5mg
    552,00€
    10mg
    949,00€
    25mg
    2.104,00€
  • N2-DMF-guanosine


    <p>N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.</p>
    Formule :C13H18N6O5
    Degré de pureté :Min. 95%
    Masse moléculaire :338.32 g/mol

    Ref: 3D-ND57528

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  • 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine

    Produit contrôlé
    CAS :
    <p>3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is a synthetic nucleoside analogue that inhibits the synthesis of DNA. It is a monophosphate and diphosphate analog of thymidine, which are incorporated into DNA during replication. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is an activator of RNA polymerase II and inhibits viral replication by inhibiting the function of reverse transcriptase. This drug has been shown to be effective against HIV in vitro and in vivo, as well as herpes simplex virus type 1. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine also has antitumor activity as it inhibits the growth of</p>
    Formule :C16H26N3O5SiD3
    Degré de pureté :Min. 95%
    Masse moléculaire :374.52 g/mol

    Ref: 3D-NA09010

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    À demander
  • 5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite


    <p>5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-PD75147

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    À demander
  • 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine


    <p>3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monoph</p>
    Formule :C38H34N8O5
    Degré de pureté :Min. 95%
    Masse moléculaire :682.73 g/mol

    Ref: 3D-NA08676

    10mg
    135,00€
    25mg
    203,00€
  • N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine


    <p>N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.</p>
    Formule :C14H19N5O6
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :353.33 g/mol

    Ref: 3D-NI08521

    10mg
    135,00€
    25mg
    188,00€
    50mg
    320,00€
    100mg
    501,00€
  • 3’,2-anhydro-2'-deoxyuridine

    CAS :
    <p>3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-MA162984

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    À demander
  • N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine

    CAS :
    <p>N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.</p>
    Formule :C23H31N5O5Si
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :485.61 g/mol

    Ref: 3D-NT57542

    1g
    338,00€
    2g
    540,00€
    5g
    914,00€
    10g
    1.240,00€
    25g
    2.181,00€
  • 3-N-Boc-5'-O-DMT-3'-fluorothymidine

    CAS :
    <p>3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.</p>
    Degré de pureté :Min. 95%

    Ref: 3D-NB14259

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    À demander
  • Kinetin riboside

    CAS :
    Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.
    Formule :C15H17N5O5
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :347.33 g/mol

    Ref: 3D-NK06717

    1g
    325,00€
    2g
    509,00€
    5g
    965,00€
    10g
    1.743,00€
    25g
    3.506,00€
  • 10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite

    CAS :
    <p>10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.</p>
    Formule :C46H82N3O7P
    Degré de pureté :(31P-Nmr) Min. 95 Area-%
    Couleur et forme :Colorless Powder
    Masse moléculaire :820.13 g/mol

    Ref: 3D-PP138032

    50mg
    233,00€
    100mg
    383,00€
    250mg
    719,00€
  • 3’-b-Amino-2’,3-dideoxy uridine

    CAS :
    <p>3’-b-Amino-2’,3-dideoxy uridine is an activator nucleoside that is a novel therapeutic agent for viral infections and cancer. It has antiviral activity against herpes simplex virus type 1 (HSV-1) and cytomegalovirus (CMV), as well as anticancer activity against human breast adenocarcinoma cells. 3’-b-Amino-2’,3-dideoxy uridine is a modified nucleoside with antiviral and anticancer properties. This drug has been shown to inhibit HSV-1 replication by interfering with the synthesis of viral DNA. 3’-b-Amino-2’,3-dideoxy uridine also inhibits the proliferation of human breast adenocarcinoma cells by inhibiting ribonucleotide reductase.</p>
    Formule :C9H13N3O4
    Degré de pureté :Min. 95%
    Masse moléculaire :227.22 g/mol

    Ref: 3D-NA144655

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    À demander
  • 5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution

    CAS :
    <p>5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.</p>
    Formule :C10H18N3O14P3·xNa
    Degré de pureté :Min. 95%
    Couleur et forme :Powder
    Masse moléculaire :497.18 g/mol

    Ref: 3D-NM11441

    1mg
    670,00€
    2mg
    949,00€
    5mg
    2.030,00€
    10mg
    3.793,00€