Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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Thymidine-3',5'-diphosphate disodium salt
CAS :Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Formule :C10H14N2Na2O11P2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.15 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS :<p>Inhibitor of adenylyl and guanylyl cyclase</p>Formule :C10H15N4O15P3·xC6H15NDegré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :524.17 g/molPolyadenylic acid potassium
CAS :<p>Please enquire for more information about Polyadenylic acid potassium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :(C10H14N5O7P)x•KxDegré de pureté :85% Min5-Methyl-L-uridine
CAS :<p>5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.</p>Formule :C10H14N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :258.23 g/mol5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å
<p>5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.</p>Couleur et forme :Powder2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
CAS :<p>2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.</p>Formule :C9H10FN3O3Degré de pureté :Min. 95%Masse moléculaire :227.19 g/mol8-Amino-2’-deoxyadenosine
CAS :<p>8-Amino-2’-deoxyadenosine (8AAD) is a nucleoside that is used in the laboratory for the analysis of dna duplexes. It stabilizes dna duplexes in an acidic environment, and it can be used to analyze the stability of dna duplexes at neutral pH. 8AAD can also stabilize triplex structures formed by 8AAD, amines, and purines. The orientation of these bases in the triplex structure is important because they can determine which strands are cleaved during hydrolysis.</p>Formule :C10H14N6O3Degré de pureté :Min. 95%Masse moléculaire :266.26 g/molN6-Benzyladenosine 5'-diphosphate sodium salt - 10 mM aqueous solution
CAS :<p>N6-Benzyladenosine 5'-diphosphate sodium salt is a modified nucleoside that has a high purity, which is suitable for synthesis of DNA or RNA. It can be used in the modification of deoxyribonucleosides, ribonucleosides, and phosphoramidites. N6-Benzyladenosine 5'-diphosphate sodium salt has been shown to have anticancer effects and antiviral effects. This drug also has novel properties such as an ability to inhibit the proliferation of cancer cells.</p>Formule :C17H21N5O10P2Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :517.32 g/mol2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS :<p>2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.</p>Formule :C21H38N2O6Si2Degré de pureté :Min. 95%Masse moléculaire :470.72 g/molPolyoxin B
CAS :<p>Polyoxin B is a natural product that is produced by the fungus Polyporus umbellatus. It is a synthetase inhibitor that specifically inhibits the enzyme malic acid synthetase in bacteria and fungi. Polyoxin B has been shown to have antifungal activity in vitro and to inhibit the growth of Cryptococcus neoformans, which may be due to its ability to inhibit terminal residues, such as acetate extract, bacterial strain, and synthase enzyme.</p>Formule :C17H25N5O13Degré de pureté :Min. 70%Couleur et forme :Yellow PowderMasse moléculaire :507.41 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite
CAS :<p>A 5'-3’ “reverse” (or “inverse”) amidites</p>Formule :C47H52N7O7PDegré de pureté :Min. 95%Masse moléculaire :857.93 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
<p>Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.</p>Formule :C32H74N7O12P3SDegré de pureté :Min. 95%Masse moléculaire :873.96 g/molN6-Aminoadenosine
CAS :<p>N6-Aminoadenosine is a purine nucleoside that is involved in the synthesis of adenosine. It can be found in a number of tissues and has been shown to have an agonist potency similar to 2-phenylaminoadenosine, but with a longer duration of action. N6-Aminoadenosine is also present as one of two stereoisomers, the other being N2-aminoadenosine. These two aminosides are hydrolyzed by triazol and sinoatrial enzymes. The affinity of N6-aminoadenosine for cellular receptors has been shown using high affinity assays on rat heart cells.</p>Degré de pureté :Min. 95%2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite
<p>2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite is a 5'-3’ “reverse” (or “inverse”) amidite.</p>Formule :C44H54N7O8PDegré de pureté :Min. 95%Masse moléculaire :839.94 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
CAS :<p>Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides containing 2’-O-(2-methoxyethyl) adenosine nucleoside units. Using a chemical approach rather than an enzymatic one allows custom-made oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with an appropriate alcohol in the presence of an azole catalyst such as imidazole or 1H-tetrazole. N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite has been used in the synthesis of 2’-modified oligonucleotides as protein binding modulators.</p>Formule :C50H58N7O9PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :932.01 g/mol4'-α-C-Methylcytidine
CAS :<p>4'-a-C-Methylcytidine is a nucleoside that is synthesized from 4'-a-C-methyluridine. It has antiviral and anticancer properties, and has been shown to be a potent activator of the immune system. The modified nucleosides in this compound are thought to be less toxic than other cytotoxic agents. 4'-a-C-Methylcytidine is also used as a building block for the synthesis of DNA, RNA and phosphoramidites.</p>Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :257.24 g/mol7-deaza-dG-CE Phosphoramidite
CAS :<p>7-deaza-dG-CE Phosphoramidite is a monophosphate nucleotide, which is synthesized by modification of the 7-deaza-dG ribonucleoside. It has an antiviral and anticancer activity, and is used as a building block for novel drugs. 7-Deaza-dG-CE phosphoramidite has been shown to inhibit tumor growth and induce apoptosis in Hep2 cells. It also inhibits HIV replication in vitro. The compound is chemically stable and does not react with other biomolecules.</p>Formule :C44H54N7O7PDegré de pureté :Min. 95%Masse moléculaire :823.9 g/molUridine diphosphate choline (UDPC) sodium
CAS :<p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>Formule :C14H25N3O12P2•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :512.3 g/molMorpholino A monomer
CAS :Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomersFormule :C38H37ClN7O4PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :722.17 g/mol[(2S,6R)-6-{N6-Benzoyladenin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS :<p>Nucleotide analogue for use in oligonucleotide synthesis</p>Formule :C38H37ClN7O4PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :722.17 g/mol
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