Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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8-Hydrazinoadenosine
CAS :<p>8-Hydrazinoadenosine is an inhibitor of phosphodiesterase, which is a key enzyme in the regulation of cellular processes. 8-Hydrazinoadenosine binds to the active site of the enzyme and inhibits its function. This binding prevents hydrolysis of the phosphate bond between two nucleotides and so prevents the formation of a new nucleotide from a nucleoside and a phosphate molecule. 8-Hydrazinoadenosine has been shown to inhibit phosphodiesterases in vitro and in animals, including rat brain and mouse lung. Strategies for 8-hydrazinoadenosine commercialization have been investigated, including attaching it to other molecules that are more easily absorbed by cells or using irradiation to produce 8-aminoadenosine, which can be converted into 8-hydrazinoadenosine.</p>Degré de pureté :Min. 95%7-Deazaadenosine- 2', 3'- dideoxy- 7[3- (trifluoroacetyl) amino] - 1- propyn- yl
CAS :<p>7-Deazaadenosine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 7-Deazaadenosine also has antiviral activity, inhibiting viral DNA synthesis by interfering with the enzyme DNA polymerase. 7-Deazaadenosine has been shown to be more potent than other deoxyribonucleosides against various HIV strains, including HIV-1 group M and HIV-1 group O. This drug was originally developed for use as a chemotherapeutic agent but has since been used as a research reagent for studying the mechanism of action of various drugs on DNA.</p>Formule :C16H16F3N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :383.33 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It is an analog of adenosine and inhibits the action of ribonucleotide reductase, which is an enzyme that converts ribonucleotides to deoxyribonucleotides. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine 3'-CE phosphoramidite also inhibits the synthesis of DNA, which may be due to its inhibition of DNA polymerase. This compound has been shown to inhibit the growth of leukemia cells in culture and induce apoptosis in human tumor cells.</p>Formule :C47H51FN7O7PDegré de pureté :Min. 95%Masse moléculaire :875.92 g/mol4-Hydroxy-6-methylpyrimidine
CAS :<p>4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.</p>Formule :C5H6N2ODegré de pureté :Min. 95%Masse moléculaire :110.11 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine
CAS :<p>2'-Deoxy-5'-O-DMT-5-iodouridine is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.</p>Formule :C30H29IN2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :656.48 g/mol2'-Deoxyadenosine 3'-O-L-valinyl ester
2'-Deoxyadenosine 3'-O-L-valinyl ester is a novel nucleoside phosphoramidite that is synthesized by activating the 2'-deoxyribose phosphate with an L-valyl chloride. This synthetic nucleoside analog can be used as a substitute for dATP in DNA synthesis and has antiviral as well as anticancer activities.Degré de pureté :Min. 95%Kinetin riboside-5'-diphosphate sodium salt
<p>Kinetin riboside-5'-diphosphate sodium salt is a synthetically modified nucleoside that is used as an activator for DNA synthesis and in the treatment of cancer. Kinetin riboside-5'-diphosphate sodium salt has been shown to have antiviral and anticancer effects, as well as being able to modify the activity of natural substances such as kinetin. This compound has been shown to inhibit tumor growth and reduce the size of some types of tumors in mice. It also inhibits viral replication by blocking viral RNA polymerase activity and inhibiting viral protein synthesis.</p>Degré de pureté :Min. 95%b-Nicotinamide adenine dinucleotide phosphate
CAS :<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formule :C21H28N7O17P3Degré de pureté :Min. 80 Area-%Couleur et forme :Off-White PowderMasse moléculaire :743.41 g/molN6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine
CAS :<p>N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral compound that inhibits the synthesis of DNA and RNA. It is a synthetic, modified nucleoside with antiviral properties. The compound has been shown to be active against both animal and human tumor cells, as well as being effective in the treatment of viral infections.N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is water soluble and biologically stable.</p>Degré de pureté :Min. 95%3'-O-Benzoyl-2'-deoxyuridine
CAS :<p>3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.</p>Formule :C16H16N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :332.31 g/molN4-Benzoyl-3'-deoxycytidine
CAS :<p>N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.</p>Formule :C16H17N3O5Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :331.32 g/mol2'-Deoxy-7-deazaisoguanosine triphosphate
CAS :<p>2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes.<br>2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.</p>Formule :C11H17N4O13P3Degré de pureté :Min. 95%Masse moléculaire :506.19 g/molN2,N2,7-Trimethylguanosine
CAS :Trimethylguanosine is a hydrogen-bonded base that is found in the DNA of all living organisms. It has a diagnostic role in cancer and metabolic disorders, as well as in the study of cell culture. Trimethylguanosine can be used to identify cancer cells by measuring its fluorescence properties, which are different from those of healthy cells. This compound also has a role in the diagnosis of metabolic disorders, such as diabetes mellitus and renal disease. Trimethylguanosine is also involved in biological function, and is necessary for the synthesis of proteins and nucleic acids.Formule :C13H20N5O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :326.33 g/mol7-Deaza 2-C-methyl-N6-methyladenosine
CAS :<p>7-Deaza 2-C-methyl-N6-methyladenosine is a nucleoside that is modified with a methyl group at the 7 position of the deoxyribose ring. It has antiviral and anticancer properties. 7-Deaza 2-C-methyl-N6-methyladenosine is an activator of phosphoramidites, which are compounds that can be used to synthesize DNA or RNA.</p>Formule :C13H18N4O4Degré de pureté :Min. 95 Area-%Masse moléculaire :294.31 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS :<p>Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.</p>Formule :C9H14N4O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :258.23 g/molN4,N4,2’-O-Trimethylcytidine
CAS :<p>N4,N4,2’-O-Trimethylcytidine is a novel nucleoside that has been shown to be an anticancer drug. It inhibits the growth of cells by selectively inhibiting their DNA synthesis. N4,N4,2’-O-Trimethylcytidine is also active against viruses and is able to inhibit viral replication by blocking the synthesis of deoxyribonucleosides and phosphoramidites. This compound has been synthesized in high purity and quality with CAS No. 34218-81-0.</p>Formule :C12H19N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :285.3 g/molAdenosine 3',5'-bisphosphate triethylammonium salt - 10mM aqueous solution
CAS :<p>Adenosine 3',5'-bisphosphate triethylammonium salt is a metabolite of adenosine and an ester of triethylamine. The conjugate acid has been isolated from mouse urine. It is a metabolite of adenosine in the liver and is hydrolyzed to adenosine monophosphate and bisphosphate. Adenosine 3',5'-bisphosphate triethylammonium salt is used to study the metabolism of adenosine in mice. It has also been shown that this metabolite can inhibit the growth of E. coli (a bacterium) and mouse erythrocyte mitochondria by blocking ATP synthesis at the level of substrate-level phosphorylation.</p>Formule :C10H15N5O10P2•(C6H15N)xDegré de pureté :Min. 95%Masse moléculaire :427.2 g/mol2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS :<p>2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is a nucleoside that is used in the synthesis of DNA. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt is an antiviral, antineoplastic, and anticancer agent. It has been shown to be active against some strains of HIV and herpes viruses. 2'-Deoxy-2'-fluorocytidine-5'-triphosphate lithium salt also inhibits DNA polymerase and RNA polymerase, preventing viral replication and transcription.<br>The phosphate group on the 5' end of this molecule can be modified to produce phosphoramidites, diphosphates, or triphosphates.</p>Formule :C9H11FN3O13P3·Li4Degré de pureté :Min. 95%Masse moléculaire :508.88 g/mol5'-Azido-2',5'-dideoxy-2'-fluorouridine
CAS :<p>5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.</p>Formule :C9H10FN5O4Degré de pureté :Min. 95%Masse moléculaire :271.21 g/molβ-Nicotinamide adenine dinucleotide sodium dihydrate
CAS :<p>Coenzyme and regenerating electron donor in catabolic processes</p>Formule :C21H26N7NaO14P2•(H2O)2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :721.44 g/mol
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