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Nucléosides

Nucléosides

Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.

3569 produits trouvés pour "Nucléosides"

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  • 2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite

    CAS :
    2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is an anticancer agent that is used to treat leukemia and other cancers. It also has antiviral activity, inhibiting the viral enzyme RNA polymerase. It is a novel synthetic nucleoside that has been shown to be active against HIV in vitro. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is a nucleotide analogue of guanosine and is phosphorylated by cellular enzymes to form 2'-deoxyguanosine 5' phosphate. This compound binds to DNA and inhibits replication by preventing the unwinding of DNA helixes during transcription. 2'-Deoxyguanosine 5' phosphate also blocks translation by inhibiting ribosomal protein synthesis at the initiation
    Formule :C44H54N7O7PS
    Degré de pureté :Min. 95%
    Masse moléculaire :855.98 g/mol

    Ref: 3D-PD158794

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  • 6- Hydroxycytidine

    CAS :

    6-Hydroxycytidine is a modified nucleoside that is used as a building block in the synthesis of DNA. It has antiviral activity and has been shown to be effective in treating cancer cells. 6-Hydroxycytidine is also used in the production of phosphoramidites, which are used to synthesize nucleotides for DNA and RNA. 6-Hydroxyl cytidine is a novel chemical that does not have an IUPAC name. CAS No: 15477-67-5

    Formule :C9H13N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :259.22 g/mol

    Ref: 3D-NH172586

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  • S-Adenosylmethione-1,4-butanedisulfonate

    CAS :
    S-adenosylmethionine is a compound that is naturally produced in the body and has been shown to be involved in many biochemical reactions. It can be found as a supplement at health food stores, but also is available as a prescription for the treatment of certain liver diseases such as hepatitis. S-adenosylmethionine may have some drug transporter function and can affect the metabolism of other drugs.
    Formule :C42H74N12O28S8
    Degré de pureté :Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :1,451.63 g/mol

    Ref: 3D-NA58198

    10g
    275,00€
    25g
    459,00€
    50g
    616,00€
    100g
    896,00€
    250g
    1.516,00€
  • N6-Benzoyl-2'-deoxy-5'-O-trityladenosine 3'-CE phosphoramidite

    CAS :
    N6-Benzoyl-2'-deoxy-5'-O-trityladenosine 3'-CE phosphoramidite is a novel nucleoside analog that inhibits the proliferation of cancer cells. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo, as well as to induce apoptosis. The monophosphate form of this compound has been shown to be an effective antiviral agent against influenza virus. This compound also has high quality and purity.
    Formule :C45H48N7O5P
    Degré de pureté :Min. 95%
    Masse moléculaire :797.9 g/mol

    Ref: 3D-PB09096

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  • 3’-Deoxy-3’-fluoro-2-thiouridine

    CAS :

    3’-Deoxy-3’-fluoro-2-thiouridine is a nucleoside analog that has been modified to have antiviral and anticancer activity. It is an activator of the ribonucleotide reductase enzyme, which is involved in DNA synthesis. 3’-Deoxy-3’-fluoro-2-thiouridine has been used successfully as an antiviral agent against HIV and other viruses, and as an anticancer agent against leukemia. The monophosphate form of this drug has been shown to inhibit DNA replication in vitro.

    Degré de pureté :Min. 95%

    Ref: 3D-ND162874

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  • N4-Acetylcytidine

    CAS :
    N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.
    Formule :C11H15N3O6
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :285.25 g/mol

    Ref: 3D-NA05753

    1kg
    4.665,00€
    50g
    485,00€
    100g
    738,00€
    250g
    1.622,00€
    500g
    2.686,00€
  • 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine

    Produit contrôlé
    CAS :
    3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is a synthetic nucleoside analogue that inhibits the synthesis of DNA. It is a monophosphate and diphosphate analog of thymidine, which are incorporated into DNA during replication. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine is an activator of RNA polymerase II and inhibits viral replication by inhibiting the function of reverse transcriptase. This drug has been shown to be effective against HIV in vitro and in vivo, as well as herpes simplex virus type 1. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxy-D3-thymidine also has antitumor activity as it inhibits the growth of
    Formule :C16H26N3O5SiD3
    Degré de pureté :Min. 95%
    Masse moléculaire :374.52 g/mol

    Ref: 3D-NA09010

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  • 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite

    CAS :
    2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-CE phosphoramidite is a nucleoside analogue that has been modified to contain an isobutyryl group. It is an activator of the polymerase enzyme, which helps to synthesize DNA. This product can be used in the synthesis of oligonucleotides for use as therapeutic or diagnostic agents. It has anticancer and antiviral activities, due to its ability to inhibit viral replication. This product also has high purity and quality.
    Formule :C44H54N7O8P
    Degré de pureté :Min. 98 Area-%
    Couleur et forme :Powder
    Masse moléculaire :839.92 g/mol

    Ref: 3D-PD08538

    10g
    270,00€
    25g
    454,00€
    50g
    658,00€
    100g
    1.094,00€
    200g
    1.748,00€
  • N2-DMF-guanosine


    N2-DMF-guanosine is a novel antiviral agent that has been synthesized by modifying the nucleoside guanosine. It is an analog of guanosine in which the 2'-hydroxyl group has been replaced with a 2'-deoxy-2'-fluoro group, and it inhibits viral replication by inhibiting viral DNA polymerase. N2-DMF-guanosine is also used as a high quality deoxyribonucleoside monophosphate for the synthesis of ribonucleosides and nucleosides. This compound has a CAS number of 6074-37-4.

    Formule :C13H18N6O5
    Degré de pureté :Min. 95%
    Masse moléculaire :338.32 g/mol

    Ref: 3D-ND57528

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  • 2'-O-Methyl-5-methylcytidine

    CAS :
    2'-O-Methyl-5-methylcytidine is a nucleoside that is categorized as a modified nucleic acid. It is structurally similar to cytidine, but has an additional methyl group. 2'-O-Methyl-5-methylcytidine stabilizes the conformational structure of nucleic acids and can be used to regulate the activity of enzymes. This modified nucleoside has been shown to have thermophilic characteristics when it interacts with human cells. The stability of 2'-O-Methyl-5-methylcytidine increases with increasing temperature, making it possible for this molecule to regulate gene expression in organisms that live at high temperatures.
    Formule :C11H17N3O5
    Degré de pureté :Min. 95%
    Couleur et forme :White Off-White Powder
    Masse moléculaire :271.27 g/mol

    Ref: 3D-NM06424

    1g
    457,00€
    2g
    717,00€
    5g
    1.120,00€
    10g
    2.078,00€
    500mg
    308,00€
  • 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine

    CAS :

    5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine is a novel nucleoside with the ability to activate ribonucleosides and phosphoramidites. It is a modified nucleoside that has been shown to have anticancer and antiviral properties. 5’-Azido-5’-deoxy-2’-O-methyl-5-methyluridine also inhibits the synthesis of viral RNA and DNA, which may result in its antiinflammatory properties. 5’-Azido-5’deoxy -2′O methyl -5′ methyl uridine has a CAS number of 187733–73–9.

    Degré de pureté :Min. 95%

    Ref: 3D-NA163037

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  • 5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite


    5'-O-DMT-N2-phenoxyacetyl-2'-O-methylguanosine 3'-CE phosphoramidite is a nucleoside analog that inhibits DNA synthesis by forming a covalent bond with the beta-subunit of DNA polymerase. It is a modified nucleoside that has been synthesized from 2'-O-methylguanosine and N2,N2-dimethoxyacetyl. 5'-O-DMT-N2-phenoxyacetyl-2'-O methylguanosine 3'-CE phosphoramidite possesses the CAS No. 16053526.
    Degré de pureté :Min. 95%

    Ref: 3D-PD75147

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  • 3’-Deoxy-3’-α-C-methyl-N6,N6-dimethyladenosine


    3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine is a nucleoside with anticancer activity. It is a novel nucleoside that has been shown to have antiviral and antitumor activities. Research has shown that 3’-Deoxy-3’-alpha-C-methyl-N6,N6-dimethyladenosine inhibits tumor growth in animals without toxicity to the normal cells of the body. This nucleoside also has an effect on DNA and RNA synthesis, which may be due to its ability to inhibit viral replication enzymes.
    Degré de pureté :Min. 95%

    Ref: 3D-ND144756

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  • 3’,2-anhydro-2'-deoxyuridine

    CAS :
    3’,2-anhydro-2'-deoxyuridine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the ribonucleotide reductase enzyme, which catalyses the conversion of ribonucleotide diphosphates to deoxynucleotides. 3’,2-anhydro-2'-deoxyuridine also inhibits DNA synthesis by cytostatic mechanisms. This product is used as a building block in phosphoramidite synthesis and can be used for the preparation of novel nucleosides and phosphoramidites. This product was originally synthesized for use as an antiviral agent against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). It is also used as an anticancer agent in preclinical research.
    Degré de pureté :Min. 95%

    Ref: 3D-MA162984

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  • 5-Fluorocytosine

    CAS :
    Flucytosine is an antifungal agent that inhibits the synthesis of DNA by preventing the conversion of deoxyuridine monophosphate to uracil monophosphate. It is used as an antiretroviral therapy in combination with other drugs, such as zidovudine and dideoxyinosine, to treat HIV infections. Flucytosine has been shown to have a strong antitumor response in a model system involving mice with sarcoma 180. This drug can cause serious side effects, including drug interactions and resistance mutations in microorganisms. These side effects are often observed in patients undergoing cancer chemotherapy or immunosuppressive therapy.
    Formule :C4H4FN3O
    Degré de pureté :Min. 95%
    Couleur et forme :White Powder
    Masse moléculaire :129.09 g/mol

    Ref: 3D-FF02813

    1kg
    741,00€
    2kg
    1.042,00€
    100g
    222,00€
    250g
    386,00€
    500g
    508,00€
  • Uridine-5'-triphosphate trisodium salt

    CAS :

    P2Y receptor agonist; precursor in RNA biosynthesisÂ

    Formule :C9H12N2Na3O15P3
    Degré de pureté :(31P Nmr) Min. 95 Area-%
    Couleur et forme :White Powder
    Masse moléculaire :550.09 g/mol

    Ref: 3D-NU03863

    2g
    343,00€
    5g
    528,00€
    10g
    738,00€
    25g
    1.285,00€
    50g
    1.901,00€
  • 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine

    CAS :
    5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine is a synthetic nucleoside that belongs to the class of deoxyribonucleosides. It is a modified nucleoside with an anisoyl group at the 5' position and a benzoyl group at the 2' position. This product can be used in the synthesis of DNA, RNA, and phosphoramidites. 5'-O-p-Anisoyl-N4-benzoyl-2',3'-dideoxycytidine has antiviral properties and has been shown to inhibit viral replication in vitro and in vivo. It also has anticancer activities as it inhibits cell proliferation and induces apoptosis, which may be due to its ability to inhibit DNA synthesis.
    Formule :C24H23N3O6
    Degré de pureté :Min. 95%
    Masse moléculaire :449.46 g/mol

    Ref: 3D-NA08684

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  • 3'-Deoxy-3'-fluorothymidine-5'-monophosphate disodium salt

    CAS :
    3'-Deoxy-3'-fluorothymidine-5'-monophosphate disodium salt is a novel antiviral drug. 3'-Deoxy-3'-fluorothymidine-5'-monophosphate disodium salt is a nucleoside analog and is synthesized by modification of the 5' phosphate group of thymidine with fluorine and chlorine. 3'-Deoxy-3'-fluorothymidine-5'-monophosphate disodium salt inhibits viral replication by competing with natural substrates for incorporation into viral DNA. It has shown to be effective in vitro against influenza A, herpes simplex virus type 1, and cytomegalovirus. 3'-Deoxy-3'-fluorothymidine-5'-monophosphate disodium salt also has anticancer properties due to its ability to inhibit DNA synthesis in human tumor cells.
    Formule :C10H12FN2Na2O7P
    Degré de pureté :Min. 95%
    Masse moléculaire :368.16 g/mol

    Ref: 3D-ND63287

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  • 3-Deazaadenosine

    CAS :
    A potential role in apoptosis and cellular senescence.
    Formule :C11H14N4O4
    Degré de pureté :Min. 99 Area-%
    Couleur et forme :Powder
    Masse moléculaire :266.26 g/mol

    Ref: 3D-ND04697

    1mg
    214,00€
    2mg
    359,00€
    5mg
    611,00€
    10mg
    1.051,00€
    25mg
    2.330,00€
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite


    2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.
    Degré de pureté :Min. 95%

    Ref: 3D-PB170565

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    À demander