Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS :3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.Formule :C15H15N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :333 g/mol5'-Ethylcarboxamidoadenosine
CAS :5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.Formule :C12H16N6O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :308.29 g/mol7-Deaza-2'-deoxyguanosine
CAS :7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.Formule :C11H14N4O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :266.26 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have notFormule :C49H56N7O9PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :918.01 g/mol5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite
Produit contrôlé5'-O-Benzoyl-D3-thymidine 3'-CE phosphoramidite is an activator for DNA synthesis and is used in the synthesis of deoxyribonucleosides as antiviral and anticancer agents. It is a modified nucleotide, which has been synthesized from thymidine. This product has shown to be effective in the treatment of cancer cells in vitro.Formule :C26H32N4O7PD3Degré de pureté :Min. 95%Masse moléculaire :549.58 g/mol3'-Amino-3'-deoxyadenosine
CAS :3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.Formule :C10H14N6O3Couleur et forme :White Off-White PowderMasse moléculaire :266.26 g/molb-Nicotinamide adenine dinucleotide phosphate sodium salt
CAS :Coenzyme and regenerating electron donor in catabolic processesFormule :C21H27N7NaO17P3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :765.39 g/mol5-Azacytidine 5'-monophosphate
CAS :5-Azacytidine 5'-monophosphate (5-Aza-CMP) is a modified nucleoside that inhibits DNA synthesis by competitively inhibiting the incorporation of deoxycytidine 5'-triphosphate into DNA. It is used as an antiviral and anticancer agent. 5-Aza-CMP has been shown to inhibit the proliferation of human cancer cells in vitro, including T cell leukemia, lymphoma, breast cancer, and melanoma.Formule :C8H13N4O8PDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :324.18 g/molN4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine
CAS :N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is a nucleoside monophosphate that is used in the treatment of HIV infection. The antiviral activity of N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is due to its ability to inhibit viral DNA synthesis by competing with natural substrates for incorporation into the growing chain. This compound also inhibits cancer cell proliferation and may be useful in the treatment of other forms of cancer. N4-Benzoyl-5'-O-benzoyl-2'-deoxycytidine is synthesized from 2,4,6,-trichlorophenylpiperazine (TCPP) and cyanogen bromide in a two step process using phosphoramidites.Formule :C23H21N3O6Degré de pureté :Min. 95%Masse moléculaire :435.44 g/mol2’-O-Acetyl-8-bromo-7-cyano-7-deaza-3’-deoxy-3’-fluoro-5’-O-toluoyladenosine
2'-O-Acetyl-8-bromo-7-cyano-7-deaza-3'-deoxy-3'-fluoro-5'-O-[toluoyl]adenosine (ABT) is a modified nucleoside that has anticancer and antiviral properties. ABT is a monophosphate nucleotide with an acetyl group at the 2' position of the ribose and a toluoyl group on the 7 position of the adenine moiety. In vitro, ABT inhibits tumor proliferation in breast cancer cells and suppresses viral replication in herpes simplex virus type 1 (HSV1) infected cells. ABT also has potential as a novel therapeutic agent for treating cancers and other diseases caused by HSV1 infection.Degré de pureté :Min. 95%4’,5’-Didehydro-2’,5’-dideoxyuridine
CAS :4’,5’-Didehydro-2’,5’-dideoxyuridine (ddU) is a monophosphate of deoxyribonucleosides. It is an antiviral drug that was originally synthesized in the 1960s to combat viral infections. It has been used as a potential anticancer agent and as an activator for complex DNA synthesis. ddU has also been used in synthesis of phosphoramidites for DNA and RNA analogues.Degré de pureté :Min. 95%2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine
2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a novel, modified nucleoside. It has antiviral activity and can be used as a building block for the synthesis of oligonucleotide analogues. 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a monophosphate that is phosphorylated to form an active ribonucleoside. It can be used in high purity as a building block for the synthesis of oligonucleotide analogues. This compound has been shown to have anticancer effects and DNA binding activities.Degré de pureté :Min. 95%5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.Formule :C31H47N4O8PSiDegré de pureté :Min. 95%Masse moléculaire :662.8 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS :2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.Formule :C13H19N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :341.32 g/mol2',3',5'-Tri-O-acetyl-2-fluoroadenosine
CAS :2',3',5'-Tri-O-acetyl-2-fluoroadenosine is nucleoside analog of adenosine for use in research. The addition of a fluorine to an adenosine can change adenosine's properties such as its hydrogen bonding ability and how it interacts with water and other biological molecules. It can also increase the stability of adenosine and increase its half-life in biological systems.
Formule :C16H18FN5O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :411.34 g/mol3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine
CAS :3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine is a synthetic nucleoside with antiviral properties. It is a monophosphate that can be used to activate other nucleosides. This product has been shown to inhibit human immunodeficiency virus (HIV) reverse transcriptase in vitro and in vivo, as well as the replication of other viruses such as herpes simplex virus (HSV).Formule :C22H41N5O4Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :495.76 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine
CAS :2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine is a synthetic nucleoside. It is an activator for DNA synthesis and has anticancer, antiviral and antifungal properties. This product can be used as a reagent in the synthesis of DNA or RNA. This compound also has high purity and high quality.Formule :C35H36FN5O7Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :657.7 g/mol5-Iodo-2’-C-methylcytidine
CAS :5-Iodo-2’-C-methylcytidine is a synthetic nucleoside that is an activator of DNA polymerases. It has been shown to be an anticancer agent and antiviral agent, with potential applications in the treatment of HIV and HBV infections. 5-Iodo-2’-C-methylcytidine is a novel monophosphate nucleoside that has been modified to improve its stability. This product is sold as a high purity, high quality, NMR grade material that can be used in research or in the manufacture of pharmaceuticals.Formule :C10H14IN3O5Degré de pureté :Min. 95%Masse moléculaire :383.14 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-O succinate TEA
N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-O succinate TEA salt (BEDOT) is a novel nucleoside analogue that is a phosphoramidite for DNA synthesis. BEDOT has shown anticancer and antiviral activity in vitro.Degré de pureté :Min. 95%5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite
5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite is an activator of DNA synthesis. It has antiviral and anticancer properties, which have been shown in animal models. This compound is a novel nucleoside phosphoramidite that can be used to synthesize oligonucleotides. The CAS number for this product is 98469-45-7.Formule :C26H35N6O5PDegré de pureté :Min. 95%Masse moléculaire :542.58 g/mol
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