Nucléosides
Les nucléosides sont des building blocks fondamentaux des acides nucléiques, composés d'une base azotée attachée à une molécule de sucre. Dans cette section, vous trouverez une large gamme de nucléosides essentiels pour la recherche en biologie moléculaire, biochimie et pharmacologie. Ces composés jouent des rôles cruciaux dans la synthèse de l'ADN et de l'ARN, et sont également vitaux dans divers processus métaboliques. Les nucléosides sont utilisés pour étudier le matériel génétique, développer des thérapies antivirales et anticancéreuses, et comprendre les mécanismes cellulaires. Chez CymitQuimica, nous proposons des nucléosides de haute qualité pour soutenir vos besoins en recherche et développement, garantissant pureté et fiabilité pour vos applications expérimentales.
3569 produits trouvés pour "Nucléosides"
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3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine
CAS :3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine is a synthetic nucleoside with antiviral properties. It is a monophosphate that can be used to activate other nucleosides. This product has been shown to inhibit human immunodeficiency virus (HIV) reverse transcriptase in vitro and in vivo, as well as the replication of other viruses such as herpes simplex virus (HSV).Formule :C22H41N5O4Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :495.76 g/mol2'-Deoxy-5'-O-MMT-inosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-MMT-inosine 3'-CE phosphoramidite is a modified nucleoside that is used in the synthesis of DNA. It has been shown to inhibit the replication of HIV, herpes simplex virus type 1 and type 2, influenza A virus and vesicular stomatitis virus. The antiviral activity has been attributed to its ability to inhibit viral DNA polymerase, which prevents viral replication. This compound also inhibits human cytomegalovirus (CMV) DNA polymerase in vitro.Formule :C39H45N6O6PDegré de pureté :Min. 95%Masse moléculaire :724.8 g/mol3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine
Produit contrôlé3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine is a novel modified nucleoside that has antiviral and anticancer properties. It is an activator of the DNA polymerase, ribonucleotide reductase, and thymidine kinase enzymes. 3'-Amino-5'-O-p-anisoyl-3'-deoxy-D3-thymidine has been shown to inhibit the growth of human cancer cells in vitro and in vivo.Formule :C18H18N3O7D3Degré de pureté :Min. 95%Masse moléculaire :394.39 g/mol6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.Degré de pureté :Min. 95%5-(Azidomethyl)-2’-deoxyuridine
CAS :5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.
Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/molIsocytidine
CAS :Isocytidine, also known as 2-amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone, have broad antitumor activity targeting indolent lymphoid malignancies.Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :243.22 g/mol8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS :Activator of cGMP-dependent protein kinasesFormule :C10H10BrN5NaO7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :446.08 g/mol2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine
2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is a novel nucleoside analog that has been shown to have anticancer, antiviral and antiretroviral activities. It binds to the ribonucleotide reductase enzyme and inhibits deoxyribonucleoside synthesis in cells. 2,3'-Anhydro-5'-O-benzoyl-N4-benzoyl-2'-deoxycytidine is also an activator of ribonucleotide reductase. This drug has been shown to be effective in treating leukemia, lymphoma, and breast cancer cells.Formule :C23H21N3O5Degré de pureté :Min. 95%Masse moléculaire :419.44 g/mol6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside which has been shown to be active against HIV and other viruses. It is a phosphoramidate of 2'-deoxyadenosine 5'-monophosphate with an amino group at the 2' position. This compound inhibits the replication of DNA by binding to the enzyme reverse transcriptase and prevents the synthesis of viral DNA. 6-Amino-4-hydrazino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine also has anticancer properties, as it inhibits cell proliferation in vitro and in vivo.Degré de pureté :Min. 95%5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine
5'-O-p-Anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is a deoxyribonucleoside that has antiviral, anticancer, and novel properties. It has a CAS No. of 49811-91-7 and a molecular weight of 290.5 g/mol. The chemical formula for 5'-0-p-anisoyl-N4-benzoyl-3'-fluoro-2',3'-dideoxycytidine is C12H14FN2O9. It is synthesized by reacting 2,6-(1H,1'H)-benzoxazinones with 3' -deoxycytidines in the presence of phosphoric acid and anhydrous zinc chloride in methanol at room temperature to form the 5'-0 p anisoyl derivative, which is then reacted withFormule :C24H22FN3O6Degré de pureté :Min. 95%Masse moléculaire :467.45 g/mol6-O-Methylinosine
CAS :6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Formule :C11H14N4O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :282.25 g/mol5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine
5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine is a novel nucleoside that is synthesized from ribonucleosides. It is an inhibitor of the RNA polymerase enzyme, which prevents the transcription and replication of DNA. 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine also inhibits viral DNA synthesis by preventing viral RNA from being translated into DNA. This product has been shown to be active against a wide range of viruses, including influenza A virus, herpes simplex virus type 1, and vaccinia virus.Formule :C16H15FN2O5Degré de pureté :Min. 95%Masse moléculaire :334.35 g/mol2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine
CAS :2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection. The molecule has high purity and high quality.Degré de pureté :Min. 95%EdU
CAS :2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.Formule :C11H12N2O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :252.23 g/mol1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D- ribo-hex-5-enofu ranosyl]uracil
5-Deoxy-2'-O-methylcytidine is a phosphoramidite nucleoside that has antiviral, anticancer, and antifungal properties. It is used as an activator in the synthesis of oligonucleotides and as a reagent for the synthesis of other nucleotide analogues. 5-Deoxy-2'-O-methylcytidine has been shown to have a novel mechanism of action, which targets DNA polymerase alpha and inhibits replication. This drug also has antiangiogenic activity, which may be due to its ability to inhibit the production of VEGF.Degré de pureté :Min. 95%2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite
2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite is a novel, modified nucleoside. It is a monophosphate and can be used as antiviral, activator or diphosphate. It has been shown to inhibit the growth of cancer cells in vitro. 2'-Deoxy-2'-fluoro-5'-O-trityluridine 3'-CE phosphoramidite also has activity against bacterial and viral pathogens and can be used for the synthesis of DNA, RNA, and other oligonucleotide compounds. This product is of high quality and purity with CAS No., Antiviral, Activator, diphosphate, Synthetic, Ribonuclesides, Deoxyribonucleosides.Formule :C37H42FN4O6PDegré de pureté :Min. 95%Masse moléculaire :688.74 g/mol2'-O-tert-Butyldimethylsilyladenosine
CAS :2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.Degré de pureté :Min. 95%Guanylyl-3'-5'-cytidine ammonium salt
CAS :Guanylyl-3'-5'-cytidine ammonium salt is a nucleoside that is classified as a diphosphate. It has high quality and novel, anticancer and cytotoxic effects. Guanylyl-3'-5'-cytidine ammonium salt is synthesized from guanosine monophosphate (GMP) and cytidine monophosphate (CMP).Formule :C19H25N8O12P·NH3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :605.46 g/mol2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine
CAS :2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.Formule :C39H37N5O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :687.76 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine is a nucleoside that is chemically modified by the addition of a benzoyl group. It has antiviral, anticancer and antiretroviral activities. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-N4-methylcytidine inhibits viral DNA synthesis by inhibiting both viral DNA polymerase and reverse transcriptase, which are enzymes required for the production of viral DNA. It also inhibits cancer cell growth by forming covalent bonds with deoxyribonucleic acid (DNA) in the cancer cells and initiating apoptosis. This nucleoside has been shown to be active against HIV, Herpes Simplex Virus Type 1 (HSV1), and Human CytomegalovDegré de pureté :Min. 95%
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