Alpha-bloquants
Les alpha-bloquants sont des composés pharmaceutiques qui agissent en inhibant l'activité des récepteurs alpha-adrénergiques, responsables de la contraction des muscles lisses. Ces médicaments sont couramment utilisés pour traiter des affections telles que l'hypertension artérielle et l'hyperplasie bénigne de la prostate, en provoquant la relaxation et la dilatation des vaisseaux sanguins. Chez CymitQuimica, nous proposons une gamme d'alpha-bloquants adaptés à la recherche en pharmacologie et en santé cardiovasculaire.
658 produits trouvés pour "Alpha-bloquants"
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N-Nitroso Mirtazapine EP Impurity D-d4 (N-Nitroso Mirtazapine USP Related Compound A-d4, N-Nitroso-N-Desmethyl Mirtazapine-d4)
Formule :C16H12D4N4OMasse moléculaire :284.361-Methyl-3-phenylpiperazine
CAS :Produit contrôlé<p>Applications Piperazine derivative used as reference materials for forensic laboratories. They affect the central and the autonomic nervous systems, the blood pressure, and smooth muscle.<br>References Brady, J., et al.: Drug Dev. Res., 20, 231 (1990), Winter, J., et al.: J. Pharmacol. Exp. Ther., 262, 682 (1992), Ator, N., et al.: Eur. J. Pharmacol., 241, 237 (1993), Forster, E., et al.: Eur. J. Pharmacol., 281, 81 (1995),<br></p>Formule :C11H16N2Couleur et forme :Off WhiteMasse moléculaire :176.262-Phenylphenol
CAS :<p>Applications 2-Phenylphenol is an agricultural fungicide and is no longer used as a food additive (1). It has been associated with the incidence of bladder cancer in male rats which may be related to its primary metabolite, phenylhydroquinone (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gouin T. et al.: Environ Pollut. 2012 Jun;165:208-14. 2. Balakrishnan, S. et al.: Environ Mol Mutagen. 2016 Apr;57(3):210-9<br></p>Formule :C12H10OCouleur et forme :Light PinkMasse moléculaire :170.212-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol
CAS :Produit contrôlé<p>Applications 2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol is an impurity found in Mirtazapine (M365000). Mirtazapine Impurity B.<br></p>Formule :C17H21N3OCouleur et forme :White To Off-WhiteMasse moléculaire :283.37(R)-(+)-5’-Hydroxyphenyl Carvedilol
CAS :<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.47(R)-Tamsulosin Hydrochloride
CAS :<p>Applications (R)-Tamsulosin is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>Formule :C20H28N2O5S·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :444.97N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS :Produit contrôlé<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Formule :C15H21N5O3·HClCouleur et forme :White To Off-WhiteMasse moléculaire :319.37 + (36.46)rac Tamsulosin Hydrochloride
CAS :Produit contrôlé<p>Applications Tamsulosin is a specific α1-adrenoceptor antagonist. Used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>Formule :C20H28N2O5S·ClHCouleur et forme :NeatMasse moléculaire :444.9733-(9H-Carbazol-4-yloxy)-1,2-propanediol
CAS :Produit contrôlé<p>Applications 3-(9H-Carbazol-4-yloxy)-1,2-propanediol is used in the synthesis of carvedilol, a β-adrenergic blocking agent.<br>References Naidu, K. et al.: Org. Chem. An Indian J., 6, 171 (2010);<br></p>Formule :C15H15NO3Couleur et forme :NeatMasse moléculaire :257.28Mirtazapine N-Glucuronide (Mixture of Diastereomers) Contains Unknown Inorganics >80%
CAS :Produit contrôlé<p>Applications Mirtazapine N-Glucuronide is a metabolite of Mirtazapine (M365000), an α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References Smith, D.A., RSC Drug Discovery Series, 1, 193 (2010); De Boer, T., et al.: Neuropharmacology, 27, 399 (1988); Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formule :C23H28N3O6Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :442.48S-Mirtazapine
CAS :Produit contrôlé<p>Applications S-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects.<br>References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)<br></p>Formule :C17H19N3Couleur et forme :NeatMasse moléculaire :265.356,7,8,9-Tetrahydro Carvedilol
CAS :Produit contrôlé<p>Applications Carvedilol (C184625) derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C24H30N2O4Couleur et forme :NeatMasse moléculaire :410.51Carvedilol
CAS :Produit contrôlé<p>Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);<br></p>Formule :C24H26N2O4Couleur et forme :WhiteMasse moléculaire :406.47(R)-(+)-Carvedilol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Formule :C24H26N2O4Couleur et forme :Off White SolidMasse moléculaire :406.47Tamsulosin
CAS :<p>Tamsulosin: an alpha1A blocker for easing urination in BPH by relaxing prostate and bladder muscles.</p>Formule :C20H28N2O5SDegré de pureté :99.93%Couleur et forme :White CrystalsMasse moléculaire :408.514-(2,3-Epoxypropoxy)carbazole
CAS :Produit contrôlé<p>Impurity Carvedilol EP Impurity D; Carvedilol USP-D<br>Applications 4-(2,3-Epoxypropoxy)carbazole (Carvedilol EP Impurity D; Carvedilol USP-D) is an intermediate in the synthesis of Carvedilol (C184625).<br></p>Formule :C15H13NO2Couleur et forme :Beige SolidMasse moléculaire :239.272-(2-Ethoxyphenoxy)ethanamine
CAS :Produit contrôlé<p>Impurity Tamsulosin EP Impurity F<br>Applications 2-(2-Ethoxyphenoxy)ethanamine (Tamsulosin EP Impurity F) is an impurity of Tamsulosin (T006350), a specific α1-adrenoceptor antagonist (1,2). It is used in the treatment of benign prostatic hypertrophy.<br>References 1. Kawabe, K. et al.: J. Urol. 1990 Oct;144(4):908-11;2. Abrams, P. et al.: Br. J. Urol. 1995 Sep;76(3):325-36.<br></p>Formule :C10H15NO2Couleur et forme :NeatMasse moléculaire :181.23Carvedilol-d3
CAS :Produit contrôléFormule :C242H3H23N2O4Couleur et forme :Off WhiteMasse moléculaire :409.498-Hydroxy Mirtazapine β-D-Glucuronide 90%
CAS :<p>Applications A metabolite of Mirtazapine (M365000). This compounds contains some of the alpha anomer.<br>References Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Dahl, M., et al.: Clin. Drug Invest., 13, 37 (1997),<br></p>Formule :C23H27N3O7Degré de pureté :90%Couleur et forme :NeatMasse moléculaire :457.485-Formyl-2-methoxy-benzenesulfonamide
CAS :Produit contrôlé<p>Impurity Tamsulosin EP Impurity E<br>Applications 5-Formyl-2-methoxy-benzenesulfonamide (Tamsulosin EP Impurity E) is an impurity of Tamsulosin (T006350), a specific α1-adrenoceptor antagonist used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>Formule :C8H9NO4SCouleur et forme :NeatMasse moléculaire :215.231-(3-Carboxy-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS :Produit contrôlé<p>Applications Mirtazapine (M365000) impurity.<br>References Reddy, T. et al.; J. Liq. Chromatogr. R. T. 31, 1204 (2008)<br></p>Formule :C17H19N3O2Couleur et forme :NeatMasse moléculaire :297.353-Hydroxy Carvedilol
CAS :Produit contrôlé<p>Applications A vascularly inactive metabolite of Carvedilol (C184625). A novel antihypertensive agent, is a potent antioxidant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Rapola, J., et al.: Lancet, 349, 1715 (1997), Gao, F., et al.: Eur. J. Pharmacol., 406, 109 (2000),<br></p>Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.472-(2-Methoxyphenoxy)ethylamine Hydrochloride
CAS :<p>Impurity Carvedilol EP Impurity E; Carvedilol Impurity E; Carvedilol USP E<br>Applications 2-(2-Methoxyphenoxy)ethylamine Hydrochloride (Carvedilol EP Impurity E; Carvedilol Impurity E; Carvedilol USP E) is an impurity of Carvedilol synthesis.<br>References Smith, L., et al.: J. Med. Chem., 20, 1653 (1977),<br></p>Formule :C9H13NO2·ClHCouleur et forme :NeatMasse moléculaire :203.67Carvedilol-d5
CAS :Produit contrôlé<p>Applications Carvedilol-d5 is the labelled analog of Carvedilol, a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>Formule :C24H21D5N2O4Couleur et forme :NeatMasse moléculaire :411.51Silodosin
CAS :<p>Applications Silodosin is an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertrophy.<br>References (1) Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995) (2) Murata, S., et al.: J. Urol., 164, 578 (2000)<br></p>Formule :C25H32F3N3O4Couleur et forme :NeatMasse moléculaire :495.53Carvedilol Bis-carbazole
CAS :Produit contrôlé<p>Impurity Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B<br>Applications Carvedilol Bis-carbazole (Carvedilol EP Impurity B; Carvedilol Impurity B; Carvedilol USP B) is an impurity from the process of Carvedilol (C184625).<br></p>Formule :C39H39N3O6Couleur et forme :Off-White To Light BeigeMasse moléculaire :645.74O-Desmethyl Carvedilol
CAS :Produit contrôlé<p>Applications A metabolite of Carvedilol (C184625), a nonselective β-adrenergic blocker with α1-blocking activity.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Formule :C23H24N2O4Couleur et forme :NeatMasse moléculaire :392.45Carvedilol N’-2-Hydroxy-3-[[2-(methoxyphenoxy)ethyl]amine
CAS :Produit contrôlé<p>Impurity Carvedilol Impurity A; Carvedilol USP A<br>Applications An impurity from the process of Carvedilol (C184625). Carvedilol impurity A. Carvedilol USP A.<br></p>Formule :C36H43N3O7Couleur et forme :NeatMasse moléculaire :629.74Mirtazapine-d3
CAS :Produit contrôlé<p>Applications An α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formule :C172H3H16N3Couleur et forme :White To BeigeMasse moléculaire :268.37Semicarbazide Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Semicarbazide Hydrochloride is a metabolite of Nitrofuran (N493840), a minor antimicrobial used in veterinary medicine affecting semicarbazide-sensitive amine oxidase (SSAO) activity (1). Semicarbazide may be found in from nitrofuran residues in honey extracts (2) as well as milk from dairy cows (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.Environmental contaminants; Food contaminants; Heat processing contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Elliott J. et al.: J Pharm Pharmacol. 1989 Jan;41(1):37-41. 2. Tribalat L. et al.: Anal Bioanal Chem. 2006 Dec;386(7-8):2161-8. 3. Chu, P. et al.: J. Agric. Food Chem. 2007 Feb:55(6);2129-2135<br></p>Formule :CH5N3O·ClHCouleur et forme :NeatMasse moléculaire :111.53N,N-Diethylcyanoacetamide
CAS :Produit contrôlé<p>Applications N,N-Diethylcyanoacetamide (cas# 26391-06-0) is a compound useful in organic synthesis.<br></p>Formule :C7H12N2OCouleur et forme :NeatMasse moléculaire :140.18N-Nitrosocarvedilol
CAS :Produit contrôléFormule :C24H25N3O5Couleur et forme :NeatMasse moléculaire :435.472Desmethyl Mirtazapine Dihydrochloride
CAS :<p>Applications A metabolite of Mirtazapine, α2-adrenergic blocker.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formule :C16H19Cl2N3Couleur et forme :White To Off-WhiteMasse moléculaire :324.251-Bromo-3-chloropropane
CAS :Produit contrôlé<p>Applications 1-Bromo-3-chloropropane can be used safer and equally efficient alternative to chloroform as a phase-separation agent in the 1-step method of RNA isolation from biological samples such as animal and plant tissue.<br>References Chomczynski, P. et al.: Anal. Biochem., 225, 163 (1995); Chey, S. et al.: Anal. Biochem., 411, 164 (2011);<br></p>Formule :C3H6BrClCouleur et forme :Colourless LiquidMasse moléculaire :157.44(R)-Tamsulosin-d4 Hydrochloride
CAS :Produit contrôlé<p>Applications (R)-Tamsulosin-d4 Hydrochloride is the labeled analogue of (R)-Tamsulosin Hydrochloride (T006350), a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990); Abrams, P., et al.: Br. J. Urol., 76, 325 (1995); Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004)<br></p>Formule :C20H25D4ClN2O5SCouleur et forme :NeatMasse moléculaire :449.0Dechloro Trazodone
CAS :Produit contrôlé<p>Impurity Trazodone Deschloro Impurity<br>Stability Hygroscopic<br>Applications A Trazodone (T718500) impurity. An antipsychotic with potential use as a schizophrenia agent. Trazodone impurity B.<br>References Pai, N. et al.: J. Chem Pharmaceut. Res., 2, 458 (2010); Silvestrini, B., et al.: Eur. J. Pharmacol., 12, 231 (1970); Brogden, R.N., et al.: Drugs, 21, 401 (1981);<br></p>Formule :C19H23N5OCouleur et forme :NeatMasse moléculaire :337.4210-Oxo Mirtazapine (Mirtazapine Impurity F)
CAS :Produit contrôlé<p>Impurity Mirtazapine EP Impurity F<br>Applications 10-Oxo Mirtazapine (Mirtazapine Impurity F) is an impurity of Mirtazapine. Mirtazapine EP Impurity F.<br>References De Boer, T., et al.: Neuropharmacol., 27, 399 (1988), Vindevogel, J., et al.: Anal. Chem., 63, 1530 (1991), Wynia, G., et al.: J. Chromatogr., 773, 339 (1997),<br></p>Formule :C17H17N3OCouleur et forme :NeatMasse moléculaire :279.342,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]
CAS :Produit contrôlé<p>Applications An impurity in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.<br>References Barve, I. et al.: Tetra., 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995), Murata, S., et al.: J. Urol., 164, 578 (2000),<br></p>Formule :C25H30F3N3O3Couleur et forme :Light YellowMasse moléculaire :477.521-Oxo Mirtazapine (Mirtazapine Impurity C)
CAS :<p>Impurity Mirtazapine EP Impurity C; Mirtazapine USP Related Compound C<br>Applications 1-Oxo Mirtazapine (Mirtazapine Impurity C; Mirtazapine USP Related Compound C) is an impurity of Mirtazapine. Mirtazapine EP Impurity C.<br>References De Boer, T., et al.: Neuropharmacol., 27, 399 (1988), Vindevogel, J., et al.: Anal. Chem., 63, 1530 (1991), Wynia, G., et al.: J. Chromatogr., 773, 339 (1997),<br></p>Formule :C17H17N3OCouleur et forme :NeatMasse moléculaire :279.34(R)-(+)-4’-Hydroxyphenyl Carvedilol
CAS :Produit contrôlé<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.47Desmethyl Mirtazapine-d6 Dihydrochloride
CAS :Produit contrôlé<p>Impurity Mirtazapine<br>Applications A labelled metabolite of Mirtazapine, α2-adrenergic blocker.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990)<br></p>Formule :C16H11D6N3·2HClCouleur et forme :NeatMasse moléculaire :330.292-(2-Aminoethoxy)anisole
CAS :Produit contrôlé<p>Applications 2-(2-Aminoethoxy)anisole is used as an additive to vinylphosphonic acid esters and acrylonitrile forming compounds displaying hypotensive activity. An impurity from the process of Carvedilol (C184625)<br>References Reznik, V. et al.: Russ. Chem. Bull., 48, 979, (1999); Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>Formule :C9H13NO2Couleur et forme :NeatMasse moléculaire :167.204’-Hydroxyphenyl Carvedilol
CAS :Produit contrôlé<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C24H26N2O5Couleur et forme :Off White SolidMasse moléculaire :422.472-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate
CAS :<p>Applications 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.<br>References Francesco, C., et al.: Eur. J. Org. Chem., 27, 6011 (2015)<br></p>Formule :C11H13F3O5SCouleur et forme :NeatMasse moléculaire :314.278N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin
CAS :Produit contrôlé<p>Impurity Tamsulosin EP Impurity A<br>Applications N-[2-(2-Ethoxyphenoxy)ethyl]-(R)-Tamsulosin (Tamsulosin EP Impurity A) is derived from 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide (A628695), which is a precursor in the synthesis of Tamsulosin (T006350) and other alpha-andregenic antagonists. (R)-Tamsulosin is a specific α1-adrenoceptor antagonist. It is used in the treatment of benign prostatic hypertrophy.<br>References Kawabe, K., et al.: J. Urol., 144, 908 (1990), Abrams, P., et al.: Br. J. Urol., 76, 325 (1995), Michel, M.C., Expert Opin. Pharmacother., 5, 151 (2004),<br></p>Formule :C30H40N2O7SCouleur et forme :NeatMasse moléculaire :572.71Mirtazapine-d4
CAS :Produit contrôlé<p>Applications Mirtazapine-d4 is the labeled analogue of Mirtazapine (M365000), which is an α2-Adrenergic blocker, analogue of Mianserin, and antidepressant.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Smith, W.T., et al.: Psychopharmacol. Bull., 26, 191 (1990);<br></p>Formule :C17H15D4N3Couleur et forme :White To Light YellowMasse moléculaire :269.386,7-Dimethoxy-N2,N2-dimethylquinazoline-2,4-diamine
CAS :Produit contrôléFormule :C12H16N4O2Couleur et forme :NeatMasse moléculaire :248.281N-Nitroso Silodosin
Produit contrôléFormule :C25H31F3N4O5Couleur et forme :NeatMasse moléculaire :524.5334-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine
CAS :<p>Applications 4-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine is an impurity of Mirtazapine (M365000). Mirtazapine impurity E.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Wynia, G., et al.: J. Chromatography, A 773, 339 (1997),<br></p>Formule :C17H21N3Couleur et forme :NeatMasse moléculaire :267.37(R)-(+)-O-Desmethyl Carvedilol
CAS :Produit contrôlé<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α-1-blocking activity. [α]D= +18.7 (c= 0.1 methanol)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., et al.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Clohs, L., et al.: J. Pharm. Biomed. Anal., 31, 407 (2003),<br></p>Formule :C23H24N2O4Couleur et forme :NeatMasse moléculaire :392.454’-Hydroxyphenyl Carvedilol-d3
CAS :Produit contrôlé<p>Applications A labelled metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C242H3H23N2O5Couleur et forme :NeatMasse moléculaire :425.49(S)-(-)-Carvedilol
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Formule :C24H26N2O4Couleur et forme :Off White SolidMasse moléculaire :406.471-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS :<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Formule :C17H18N4Couleur et forme :Light Yellow To BrownMasse moléculaire :278.35(S)-(-)-4’-Hydroxyphenyl Carvedilol
CAS :Produit contrôlé<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.47Tamsulosin Sulfonamide Chloroacetyl
Produit contrôléFormule :C14H18Cl2N2O5SCouleur et forme :NeatMasse moléculaire :397.2741-[3-(Dimethylamino)propyl]-3-ethylurea
CAS :Produit contrôlé<p>Applications 1-[3-(Dimethylamino)propyl]-3-ethylurea is a reagent used in the preparation of water soluble, multifunctional antibody-porphyrin gold nanoparticles.<br>References Penon, O. et al.: J. Colloid. Inter. Sci., 496, 100 (2017);<br></p>Formule :C8H19N3OCouleur et forme :NeatMasse moléculaire :173.26Desmethyl 2N-Nitroso Mirtazapine-d6 (major)
Produit contrôléFormule :C16D6H10N4OCouleur et forme :Neat1,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS :Produit contrôlé<p>Applications A carvedilol Impurity.<br></p>Formule :C27H22N2O3Couleur et forme :NeatMasse moléculaire :422.48Alfuzosin
CAS :<p>Alfuzosin (SL 77499) is an alpha-1 adrenergic antagonist used to treat benign prostatic hypertrophy and urethral dysfunction.</p>Formule :C19H27N5O4Degré de pureté :99.64%Couleur et forme :White Crystaline PowderMasse moléculaire :389.45Carvedilol b-D-Glucuronide (mixture of diasteromers)
CAS :Produit contrôlé<p>Applications A metabolite of Carvedilol (C184625).<br>References McGurk, K., et al.: Biochem. Pharmacol., 55, 1005 (1998), Tukey, R., et al.: Annu. Rev. Pharmacol. Toxicol., 40, 581 (2000), Bowalgaha, K., et al.: Br. J. Clin. Pharmacol., 52, 605 (2001), Richardson, T., et al.: Drug Metab. Dispos., 34, 351 (2006),<br></p>Formule :C30H34N2O10Couleur et forme :NeatMasse moléculaire :582.60(R)-De(aminosulfonyl) Tamsulosin
CAS :Produit contrôléFormule :C20H27NO3Couleur et forme :NeatMasse moléculaire :329.43N-Benzyl Carvedilol
CAS :Produit contrôlé<p>Impurity Carvedilol EP Impurity C; Carvedilol Impurity C; Carvedilol USP C<br>Applications N-Benzyl Carvedilol (Carvedilol EP Impurity C) is an impurity of Carvedilol (C184625) and a degradation product in Carvedilol tablets.<br>References Karle, C., et al.: Cardiovasc. Res., 49, 361 (2001), Chen, J., et al.: Acta Cardiol. Sin., 19, 93 (2003), Xiang, T., et al.: Pharm. Res., 22, 1205 (2005),<br></p>Formule :C31H32N2O4Couleur et forme :NeatMasse moléculaire :496.604-Amino-2-chloro-6,7-dimethoxyquinazoline
CAS :<p>4-Amino-2-chloro-6,7-dimethoxyquinazoline (4ACDMQ) is a synthetic compound that has been used as a chemical intermediate. The chemical structure of 4ACDMQ is similar to that of the natural amino acid tryptophan. It is synthesized by reacting phosphorus pentachloride with 2,6,7-trimethoxyquinazoline in the presence of hydroxide solution and hexamethylphosphoramide. 4ACDMQ has been shown to be an inhibitor of ubiquitin proteasome system and has been used in functional studies on this system. The reaction yield for 4ACDMQ can be increased by using sodium hydroxide solution or n-dimethyl formamide as a solvent. Functional assays have shown binding properties for 4ACDMQ to proteins such as ubiquitin and proteasome subunits.</p>Formule :C10H10ClN3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :239.66 g/mol4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde
CAS :<p>4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinecarboxaldehyde is a synthetic chemical compound that has not been approved by the FDA. It is a metabolite of the drug product 4-(4-amino-6,7-dimethoxyquinazolin-2yl)-1-piperazinecarboxylic acid hydrochloride. The CAS number for this chemical is 102714-74-9. This product has been synthesized in our laboratory and is available for purchase at Custom Synthesis. This product can be used as an impurity standard for HPLC analysis or as a research and development chemical for drug development and pharmacopoeia purposes.</p>Formule :C15H19N5O3Degré de pureté :Min. 95%Masse moléculaire :317.34 g/molTrazodone hydrochloride impurity C
<p>Trazodone is a psychotropic agent that belongs to the group of antidepressants. Trazodone hydrochloride impurity C is a metabolite of trazodone and can be used as an impurity standard for the drug product in pharmacopoeia. Trazodone hydrochloride impurity C has been found in urine, blood, and saliva after administration of trazodone. It is also found in the plasma of pregnant women who are taking trazodone to treat depression or anxiety during pregnancy. <br>Trazodone hydrochloride impurity C is synthesized using a custom synthesis with high purity. It has been shown to have a niche market as an analytical reference material for HPLC standards.</p>Formule :C19H23Cl2N5ODegré de pureté :Min. 95%Masse moléculaire :408.32 g/mol[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanyl-methanone
CAS :<p>Leflunomide is a drug that belongs to the class of pyridones. It is used in the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis. Leflunomide inhibits ATP-binding cassette transporter A1 (ABCA1) and P-glycoprotein (Pgp) which are membrane proteins involved in the transport of lipophilic molecules across cellular membranes. Leflunomide also has been shown to inhibit 5-hydroxytryptamine2 receptors (5HT2 receptors). This inhibition may be responsible for leflunomide's effect on water retention. Leflunomide is metabolized into leflunic acid by cytochrome P450 enzymes, mainly CYP3A4. The activity of leflunic acid is similar to that of leflunomide.</p>Formule :C19H21N5O4Degré de pureté :Min. 95%Masse moléculaire :383.4 g/molTrazodone Hydrochloride Impurity G
<p>Trazodone Hydrochloride Impurity G is a synthetic compound that is an impurity found in Trazodone Hydrochloride, CAS No. 77893-17-6. This compound has the following physical properties: MW = 284.27, mp = 227-229°C, [α] D = -33.5° (c 1.0 in water), and UV max (λ max ) = 228 nm. It has been shown that this compound is not metabolized by human enzymes and is found to be natural. It can be used as a standard for HPLC analysis of Trazodone Hydrochloride Impurities A-F with the following retention times: 8.7 min for Impurity A, 9.2 min for Impurity B, 9.9 min for Impurity C, 10.4 min for Impurity D, 11.1 min for Impurity E, and 12.3 min for Impurity F.BR>BR</p>Formule :C17H27ClN2O·HClDegré de pureté :Min. 95%Masse moléculaire :347.32 g/mol
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