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Système complémentaire

Système complémentaire

Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.

169 produits trouvés pour "Système complémentaire"

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  • PIC1 PA TFA


    PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.
    Formule :C71H123N19O21S2·xC2HF3O2
    Couleur et forme :Solid
  • Compstatin TFA


    <p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>
    Formule :C68H100F3N23O19S2
    Couleur et forme :Solid
    Masse moléculaire :1664.79
  • PMX 205

    CAS :
    PMX 205 is an effective complement antagonist of the C5a receptor.
    Formule :C45H62N10O6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :839.04
  • Claseprubart

    CAS :
    <p>Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.</p>
    Couleur et forme :Liquid
  • C1q Protein (Cyno)


    C1qProtein (Cyno) is a subunit of the complement system. It recognizes various ligands and is involved in maintaining immune system balance, promoting tissue repair, and defending against pathogens.
    Couleur et forme :Odour Solid
  • C2 Protein (human)


    C2 Protein (human) is a naturally glycosylated peptide with a 20-amino acid signal sequence. It plays a critical regulatory role in the early activation stages of the classical pathway and is involved in the formation of the classical pathway C3 convertase, C4b2a.
    Couleur et forme :Odour Solid
  • JPE-1375

    CAS :
    JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.
    Formule :C49H63FN10O9
    Couleur et forme :Solid
    Masse moléculaire :955.08
  • Olendalizumab

    CAS :
    Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.
    Couleur et forme :Liquid
  • PMX-53

    CAS :
    PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.
    Formule :C47H65N11O7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :896.09
  • POT-4 TFA


    POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.
    Formule :C74H103F3N22O20S2
    Couleur et forme :Solid
    Masse moléculaire :1741.87
  • Human Immunoglobulin M


    <p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>
    Couleur et forme :Odour Solid
  • PMX 205 Trifluoroacetate


    PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
    Formule :C47H63F3N10O8
    Couleur et forme :Solid
    Masse moléculaire :953.06
  • Certepetide

    CAS :
    Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.
    Formule :C37H60N14O14S2
    Couleur et forme :Solid
    Masse moléculaire :989.09
  • Vemircopan

    CAS :
    Vemircopan is a complement factor D inhibitor.
    Formule :C29H28BrN7O3
    Couleur et forme :Solid
    Masse moléculaire :602.493
  • L-156,602

    CAS :
    L-156,602 has a wide range of applications in life science related research.
    Formule :C38H64N8O13
    Couleur et forme :Solid
    Masse moléculaire :840.973
  • Factor B-IN-1

    CAS :
    <p>Factor B-IN-1 is a Factor B inhibitor.</p>
    Formule :C19H16N4O2
    Couleur et forme :Solid
    Masse moléculaire :332.3559
  • Pegcetacoplan acetate


    <p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>
    Couleur et forme :Odour Solid
  • TLQP-21

    CAS :
    TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.
    Formule :C107H170N40O26
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :2432.75
  • AMY-101

    CAS :
    AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.
    Formule :C83H117N23O18S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1789.11
  • tLyP-1 peptide

    CAS :
    <p>tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.</p>
    Formule :C31H59N15O10S
    Couleur et forme :Solid
    Masse moléculaire :833.96