Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
191 produits trouvés pour "Système complémentaire".
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Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formule :C128H190N24O33Couleur et forme :SolidMasse moléculaire :2593.02C3a (70-77) (TFA)
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.Formule :C37H62F3N13O12Degré de pureté :99.92%Couleur et forme :White SolidMasse moléculaire :937.96C5a Anaphylatoxin (human)
CAS :C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormule :C350H578N108O107S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :8267.51Factor B-IN-5
CAS :Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.Formule :C27H32N2O4Degré de pureté :99.71%Couleur et forme :White SolidMasse moléculaire :448.55PMX 205
CAS :PMX 205 is an effective complement antagonist of the C5a receptor.Formule :C45H62N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.04ATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Formule :C42H62F3N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :954PIC1 PA
CAS :PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q.Formule :C71H123N19O21S2Couleur et forme :SolidMasse moléculaire :1642.98Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated C3 inhibitory peptide used in complement regulation and C3-mediated immune pathway research.Formule :(C2H4O)nC170H248N50O47S4·xC2H4O2Degré de pureté :97.10%Couleur et forme :Odour SolidMasse moléculaire :1501.7tLyP-1 peptide
CAS :tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formule :C31H59N15O10SCouleur et forme :SolidMasse moléculaire :833.96Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formule :C68H100F3N23O19S2Couleur et forme :SolidMasse moléculaire :1664.79C5a Receptor agonist, mouse, human
CAS :C5a Receptor Agonist (mouse, human) is a bioactive peptide derived from the C-terminus of the complement fragment 5 anaphylatoxin (C5a), functioning as anFormule :C44H72N10O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :853.11ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Couleur et forme :SolidMasse moléculaire :120702.76Omoprubart
CAS :Omoprubart is an anti-C5 humanized monoclonal antibody blocking C5 cleavage and MAC formation (EC50 = 3.473 ng/mL) for PNH and complement research.Masse moléculaire :~148 kDaJPE-1375
CAS :JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Formule :C49H63FN10O9Couleur et forme :SolidMasse moléculaire :955.0845PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :SolidFactor B-IN-1
CAS :Factor B-IN-1 is a Factor B inhibitor.Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.3559Certepetide
CAS :Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.Formule :C37H60N14O14S2Couleur et forme :SolidMasse moléculaire :989.088PMX-53
CAS :PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Formule :C47H65N11O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :896.09TLQP-21
CAS :TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Formule :C107H170N40O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2432.75BM213
CAS :BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formule :C43H70N12O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :915.0903
