Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
169 produits trouvés pour "Système complémentaire"
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Compstatin TFA
<p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>Formule :C68H100F3N23O19S2Couleur et forme :SolidMasse moléculaire :1664.79Pegcetacoplan acetate
<p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>Couleur et forme :Odour SolidHuman Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Couleur et forme :Odour SolidPMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Pozelimab
CAS :<p>Pozelimab (REGN 3918) is a humanized antibody targeting component 5 (C5), used for research on Pozelimab disease.</p>Degré de pureté :98.94% (SEC-HPLC) - 98.94% (SEC-HPLC)Couleur et forme :LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Formule :C74H103F3N22O20S2Couleur et forme :SolidMasse moléculaire :1741.87Vemircopan
CAS :Vemircopan is a complement factor D inhibitor.Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493L-156,602
CAS :L-156,602 has a wide range of applications in life science related research.Formule :C38H64N8O13Couleur et forme :SolidMasse moléculaire :840.973C2 Protein (human)
C2 Protein (human) is a naturally glycosylated peptide with a 20-amino acid signal sequence. It plays a critical regulatory role in the early activation stages of the classical pathway and is involved in the formation of the classical pathway C3 convertase, C4b2a.Couleur et forme :Odour SolidGreziprubart
Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Couleur et forme :Odour Liquid3-Phenoxybenzaldehyde
CAS :<p>3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.</p>Formule :C13H10O2Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :198.22CP-289
CAS :<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Formule :C30H35ClN2O2Degré de pureté :99.97%Couleur et forme :SoildMasse moléculaire :491.06C1q Protein (rat)
C1qProtein (Rat) is a subunit of the complement system. It can recognize various ligands and plays a role in maintaining immune system balance, promoting tissue repair, and defending against pathogens.Couleur et forme :Odour SolidtLyP-1 peptide
CAS :<p>tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.</p>Formule :C31H59N15O10SCouleur et forme :SolidMasse moléculaire :833.96CK3 peptide
CAS :<p>CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.</p>Formule :C40H72N12O12S2Couleur et forme :SolidMasse moléculaire :977.203BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formule :C14H11ClN2O2S2Degré de pureté :99.71%Couleur et forme :SoildMasse moléculaire :338.83Vensobafusp alfa
CAS :Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Couleur et forme :LiquidComplement C5 Protein, Cynomolgus, Recombinant (His)
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
Expression system: HEK293 Cells<br>Length: 25-1663, Full Length of Mature Protein<br>Activity: Not TestedCouleur et forme :Lyophilized PowderMasse moléculaire :187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)Complement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Couleur et forme :Lyophilized PowderMasse moléculaire :82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.
