Système complémentaire
Le système du complément est une partie cruciale de la réponse immunitaire, composée d'une série de petites protéines qui améliorent la capacité des anticorps et des cellules phagocytaires à éliminer les agents pathogènes d'un organisme. Ces protéines travaillent ensemble pour opsoniser les agents pathogènes, induire des réponses inflammatoires et lyser directement les membranes des pathogènes, jouant un rôle vital dans l'immunité innée et la fonction immunitaire globale. Chez CymitQuimica, nous proposons des protéines du système du complément de haute qualité pour soutenir vos études immunologiques et recherches cliniques.
178 produits trouvés pour "Système complémentaire".
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Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Formule :C68H100F3N23O19S2Couleur et forme :SolidMasse moléculaire :1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Couleur et forme :Odour SolidComplement C1s-IN-1
CAS :Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexesFormule :C22H20F2N6ODegré de pureté :97.77%Couleur et forme :Yellow SolidMasse moléculaire :422.43Vemircopan
CAS :Vemircopan is a complement factor D inhibitor.Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493AMY-101
CAS :AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Formule :C83H117N23O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1789.11Zilucoplan (PEG2)
Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).Formule :C128H190N24O33Couleur et forme :SolidMasse moléculaire :2593.02C5a Anaphylatoxin (human)
CAS :C5a Anaphylatoxin (human) is a pro-inflammatory peptide that functions as a leukocyte chemoattractant, utilized in researching inflammation and immune responsesFormule :C350H578N108O107S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :8267.51tLyP-1 peptide
CAS :tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.Formule :C31H59N15O10SCouleur et forme :SolidMasse moléculaire :833.96CK3 peptide
CAS :CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.Formule :C40H72N12O12S2Couleur et forme :SolidMasse moléculaire :977.203BCX 1470 hydrochloride
BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.Formule :C14H11ClN2O2S2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :338.83Vensobafusp alfa
CAS :Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Couleur et forme :LiquidOlendalizumab
CAS :Olendalizumab is an anti-C5a mAb that inhibits neutrophil activation and cytokine storms by blocking the C5a/C5aR axis for sepsis and viral infection research.Couleur et forme :LiquidPOT-4 TFA
POT-4 TFA, a Compstatin derivative, inhibits C3 activation, for macular degeneration research.Formule :C74H103F3N22O20S2Couleur et forme :SolidMasse moléculaire :1741.87BM213
CAS :BM213 is a useful organic compound for research related to life sciences and the catalog number is T35399.Formule :C43H70N12O10Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :915.09Campneoside II
CAS :Campneoside II, a compound extracted from the wood of Paulownia tomentosa var. tomentosa, demonstrates remarkable anti-complement activity [1].Formule :C29H36O16Couleur et forme :SolidMasse moléculaire :640.59PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :Solid3-Phenoxybenzaldehyde
CAS :3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.Formule :C13H10O2Degré de pureté :99.01%Couleur et forme :Transparent LiquidMasse moléculaire :198.22ASP-1948
ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.Couleur et forme :Odour LiquidComplement C2 Protein, Cynomolgus, Recombinant (His)
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).Couleur et forme :Lyophilized PowderMasse moléculaire :82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.Couleur et forme :Lyophilized PowderMasse moléculaire :95-120 KDa (reducing condition)Ref: TM-TMPJ-00980
5µg104,00€10µg170,00€20µg263,00€50µg490,00€100µg712,00€200µg1.035,00€500µg1.710,00€1mg2.457,00€
