Dérivés des Purines et Pyrimidines
Les purines possèdent une structure bicyclique, composée d’un cycle à six membres fusionné avec un cycle à cinq membres, tous deux contenant des atomes d’azote à des positions clés. Les dérivés des purines, tels que l’adénine et la guanine, sont essentiels à la formation de l’ADN et de l’ARN. Ces composés ont des applications thérapeutiques dans le traitement du cancer et des maladies virales en inhibant la réplication cellulaire. Les pyrimidines, quant à elles, possèdent une structure monocyclique à six membres avec deux atomes d’azote. Leurs dérivés, tels que la cytosine, la thymine et l’uracile, sont également des composants essentiels de l’ADN et de l’ARN et sont utilisés en chimiothérapie et dans les traitements antiviraux.
Chez CymitQuimica, nous proposons des dérivés des purines et pyrimidines pour la recherche en biologie moléculaire, génomique et le développement de thérapies innovantes.
8888 produits trouvés pour "Dérivés des Purines et Pyrimidines"
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(4-Amino-2-methylpyrimidin-5-yl)methanol hydrochloride
CAS :Formule :C6H10ClN3ODegré de pureté :98%Masse moléculaire :175.624-(Piperazin-1-yl)-6-(trifluoromethyl)pyrimidine dihydrochloride
CAS :Formule :C9H13Cl2F3N4Masse moléculaire :305.132-(3-Chlorophenyl)pyrimidine-4-carboxylic acid
CAS :Degré de pureté :97%Masse moléculaire :234.63999941-(Pyrimidin-4-yl)piperidine-4-carboxylic acid
CAS :Formule :C10H13N3O2Couleur et forme :SolidMasse moléculaire :207.2332-mercapto-6-(methoxymethyl)pyrimidin-4-ol
CAS :Formule :C6H8N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :172.24-[6-(2-Trifluoromethyl-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Formule :C16H11F3N4Degré de pureté :95.0%Masse moléculaire :316.2873-(2,4-DIMETHOXYPYRIMIDIN-5-YL)CYCLOHEXANONE
Formule :C12H16N2O3Degré de pureté :95.0%Masse moléculaire :236.2715-Ethynylpyrimidine-2,4(1H,3H)-dione
CAS :Formule :C6H4N2O2Degré de pureté :98%Couleur et forme :Liquid, No data available.Masse moléculaire :136.11ETHYL 2-(TERT-BUTYL)-4-CHLOROPYRIMIDINE-5-CARBOXYLATE
CAS :Formule :C11H15ClN2O2Degré de pureté :≥95%Masse moléculaire :242.7N-(4-(4-Fluorophenyl)-5-formyl-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide
CAS :Formule :C16H18FN3O3SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :351.46-Phenyl-pyrimidine-2,4-diol
CAS :Formule :C10H8N2O2Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :188.1862-(METHYLTHIO)-4-(4-(TRIFLUOROMETHYL)PHENYLAMINO)PYRIMIDINE-5-CARBOXYLIC ACID
CAS :Formule :C13H10F3N3O2SDegré de pureté :95.0%Masse moléculaire :329.3Ethyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate
CAS :Formule :C8H9BrN2O2SDegré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :277.144-(4-Amino-phenyl)-pyrimidine-2-thiol
CAS :Formule :C10H9N3SDegré de pureté :95.0%Masse moléculaire :203.262-Cyanopyrimidine-5-carboxylic acid
CAS :Formule :C6H3N3O2Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :149.1095-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid
CAS :Degré de pureté :96%Masse moléculaire :156.09700015-Bromo-2-(2-chlorophenoxy)pyrimidine
CAS :Formule :C10H6BrClN2ODegré de pureté :97.0%Masse moléculaire :285.53(S)-1-(Pyrimidin-4-yl)piperidin-3-aminedihydrochloride
CAS :Formule :C9H16Cl2N4Masse moléculaire :251.162-(Trifluoromethyl)pyrimidine-4-carboxylic acid
CAS :Formule :C6H3F3N2O2Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :192.097Ref: 10-F216995
1g497,00€5g1.631,00€10g3.132,00€2.5g985,00€50mg91,00€100mg127,00€250mg201,00€500mg358,00€2-Amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-1H-purin-6(9H)-one
CAS :Formule :C9H13N5O4Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :255.2344-chloro-5-ethyl-2,6-dimethylpyrimidine
CAS :Formule :C8H11ClN2Degré de pureté :95.0%Masse moléculaire :170.64Methyl 2,6-dichloro-5-iodopyrimidine-4-carboxylate
CAS :Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :332.91000372-Amino-5-methoxypyrimidine
CAS :Formule :C5H7N3ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :125.1314-Amino-6-(4-methyl-1-piperazinyl)pyrimidine
CAS :Formule :C9H15N5Degré de pureté :95%Couleur et forme :Solid, White powderMasse moléculaire :193.2546-Chloropyrimidin-2(1H)-one
CAS :Formule :C4H3ClN2ODegré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :130.53Ethyl 1-(pyrimidin-4-yl)-1H-imidazole-4-carboxylate
CAS :Formule :C10H10N4O2Masse moléculaire :218.2161-(2-AMINOETHYL)-3-PHENYLUREA HYDROCHLORIDE
CAS :Formule :C9H14ClN3ODegré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :215.682-Chloro-5-(cyclopropylmethoxy)pyrimidine
CAS :Formule :C8H9ClN2ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :184.62N,N-Dimethylguanosine
CAS :Formule :C12H17N5O5Degré de pureté :95.0%Couleur et forme :Solid, Crystalline or PowderMasse moléculaire :311.298(R)-3-(6-Methoxy-2-methylsulfanyl-pyrimidin-4-yloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester
CAS :Formule :C15H23N3O4SDegré de pureté :97%Masse moléculaire :341.43N-[(piperidin-4-yl)methyl]pyrimidin-2-amine dihydrochloride
CAS :Formule :C10H18Cl2N4Masse moléculaire :265.18(2-ISOPROPYLPYRIMIDIN-5-YL)BORONIC ACID PINACOL ESTER
CAS :Formule :C13H21BN2O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :248.134-Amino-6-methyl-2-(methylthio)pyrimidine-5-carbaldehyde
CAS :Formule :C7H9N3OSDegré de pureté :95.0%Masse moléculaire :183.235-Bromo-2-(p-tolyloxy)pyrimidine
CAS :Formule :C11H9BrN2ODegré de pureté :97.0%Masse moléculaire :265.111-[5-(hydroxymethyl)pyrimidin-2-yl]piperidin-4-ol
CAS :Degré de pureté :97%Masse moléculaire :209.24899294-Chloro-5-methyl-2-(methylthio)pyrimidine
CAS :Formule :C6H7ClN2SDegré de pureté :95%Couleur et forme :LiquidMasse moléculaire :174.65N,N,N’,N’-tetramethyl-N”-[3-(trimethoxysilyl)propyl]guanidine
CAS :Degré de pureté :97%Masse moléculaire :277.44000244-((2,4-DIAMINOPYRIMIDIN-5-YL)METHYL)-2,6-DIMETHOXYPHENOL
CAS :Degré de pureté :95%Masse moléculaire :276.295992-Amino-9-(4-hydroxy-3-(hydroxymethyl)butyl)-1H-purin-6(9H)-one
CAS :Degré de pureté :98%Masse moléculaire :253.2619934nPOC-POC Tenofovir Fumarate(Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formule :C19H30N5O10P·C4H4O4Couleur et forme :White To Off-WhiteMasse moléculaire :635.511-Methyl-1,4-dihydronicotinamide
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 1-Methyl-1,4-dihydronicotinamide (cas# 17750-23-1) is a compound useful in organic synthesis.<br></p>Formule :C7H10N2OCouleur et forme :NeatMasse moléculaire :138.17Diethyl p-Toluenesulfonyloxymethylphosphonate
CAS :Produit contrôlé<p>Applications Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formule :C12H19O6PSCouleur et forme :NeatMasse moléculaire :322.31Hydroxy Urea-15N
CAS :Produit contrôlé<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Formule :CH415NNO2Couleur et forme :NeatMasse moléculaire :77.055-Aminoimidazole-4-carboxamide-15N2 Hydrochloride (>90%)
CAS :Produit contrôléFormule :C4H7ClN215N2ODegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :164.56nPOC-POC Tenofovir(Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications An impurity of Tenofovir (T018500(P)). Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formule :C19H30N5O10PCouleur et forme :NeatMasse moléculaire :519.44Oseltamivir Acid Methyl Ester Phosphate Salt
CAS :<p>Applications An impurity of the antiviral drug Oseltamivir (O700100). It is a COVID19-related research product.<br></p>Formule :C15H29N2O8PCouleur et forme :NeatMasse moléculaire :396.37Methotrexate Tetraglutamate Trifluoroacetate
CAS :Produit contrôlé<p>Applications Methotrexate Tetraglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formule :C35H43N11O14xC2HF3O2Couleur et forme :NeatMasse moléculaire :841.78Almotriptan Dimer Impurity
CAS :Formule :C30H41N5O2SCouleur et forme :Off White SolidMasse moléculaire :535.741,11b-Dedihydrotetrabenazine
CAS :Produit contrôlé<p>Applications 1,11b-Dedihydrotetrabenazine is a product of photolytic degradation of Tetrabenazine (T284000) which is a dopamine depleting agent.<br>References Bourezg, Z., et al.: J. Pharmaceut. Biomed., 91, 138 (2014); Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966); Janovic, J., et al.: Ann. Neurol., 11, 41 (1982); Janovic, J., et al.: Neurology, 38, 391 (1988);<br></p>Formule :C19H25NO3Couleur et forme :NeatMasse moléculaire :315.41Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formule :C20H33N6O9PCouleur et forme :NeatMasse moléculaire :532.48Caffeidine Acid
CAS :Produit contrôlé<p>Applications Caffeidine Acid is a degradation compound of Caffeine (C080100), which is a central nervous system stimulant.<br>References Kigasawa, K., et al.: Chem. Pharm. Bull., 22, 2448 (1974); Peinhardt, G.: Pharmazie, 46, 812 (1991); Kumar, R., et al.: Carcinogenesis, 13, 2179 (1992);<br></p>Formule :C8H12N4O3Couleur et forme :NeatMasse moléculaire :212.215-Hydroxymethyl-N,N-dimethyltryptamine
CAS :Produit contrôlé<p>Applications Degradation product of Sumatriptan Succinate (S810000).<br>References Xu, X. et al.: J. Pharmaceut. Biomed. 367, 26 (2001)<br></p>Formule :C13H18N2OCouleur et forme :WhiteMasse moléculaire :218.29Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate
Produit contrôlé<p>Applications Ethyl 2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylate, is an impurity in the synthesis of Febuxostat n-Butyl Isomer (F229035).<br></p>Formule :C18H20N2O3SCouleur et forme :NeatMasse moléculaire :344.43(N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer
CAS :Produit contrôlé<p>Impurity Zolmitriptan USP Related Compound F<br>Stability Hygroscopic<br>Applications (N,N-Dimethyl-1-butanamine) Zolmitriptan Dimer (Zolmitriptan USP Related Compound F) is an impurity from the synthesis of Zolmitriptan (Z639000). Zolmitriptan is a Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>Formule :C38H53N7O4Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :671.878-13C-Uric Acid (contains ~1.5% unlabelled)
CAS :Produit contrôlé<p>Applications 8-13C-Uric Acid is the labeled analogue of Uric Acid (U829200), a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006)<br></p>Formule :C413CH4N4O3Couleur et forme :NeatMasse moléculaire :169.1Pemetrexed L-Glutamic Acid Trisodium Salt (~90%)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Pemetrexed L-Glutamic acid is an impurity of Pemetrexed (P219500). Pemetrexed impurity D.<br></p>Formule :C25H25N6O9·3NaDegré de pureté :~90%Couleur et forme :NeatMasse moléculaire :622.471-Nitroso-3,5-dimethyladamantane
CAS :Produit contrôléFormule :C12H19NOCouleur et forme :NeatMasse moléculaire :193.285rac-Clopidogrel Hydrogen Sulfate
CAS :Produit contrôlé<p>Applications rac-Clopidogrel Hydrogen Sulfate is used in the synthesis of Clopidogrel derivatives as platelet aggregation inhibitors.<br>References Chen, J., et. al.: Hecheng Huaxue, 18, 586 (2010); Defreyn, G. et al.: Thromb. Haemo., 65, 186 (1991);<br></p>Formule :C16H16ClNO2S·H2O4SCouleur et forme :Off-WhiteMasse moléculaire :419.90Sumatriptan N-Oxide
CAS :Produit contrôlé<p>Impurity Sumatriptan EP Impurity D<br>Stability Hygroscopic, Unstable in DMSO<br>Applications Sumatriptan N-Oxide (Sumatriptan EP Impurity D) is the degradation product of the antimigraine drug Sumatriptan (S810000).<br>References Xu, X. et al.: J. Pharmac. Biomed. Anal., 26, 367 (2001); Cheng, K.N. et al.: J. Pharmac. Biomed. Anal., 17, 399 (1998);<br></p>Formule :C14H21N3O3SCouleur et forme :Light Beige To Light BrownMasse moléculaire :311.40[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester
CAS :Produit contrôlé<p>Applications [[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]monophenylester is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor, used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005); Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007);<br></p>Formule :C15H18N5O4PCouleur et forme :NeatMasse moléculaire :363.31(S)-9-[2-(Hydroxypropyl] Adenine
CAS :<p>Applications (S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506).<br>References Roux, L. et al.: Eur. J. Med. Chem., 63, 869 (2013); Schaeffer, H. et al.: J. Med. Chem., 15, 456 (1972); Schaeffer, H. & Vince, R.: J. Med. Chem., 10, 689 (1967)<br></p>Formule :C8H11N5OCouleur et forme :Off White SolidMasse moléculaire :193.2062-Oxo Clopidogrel-13C,d3 Hydrochloride(Mixture of Diastereomers)
CAS :Produit contrôléFormule :C1513CH14D3Cl2NO3SCouleur et forme :NeatMasse moléculaire :378.29Urea-d4
CAS :Produit contrôlé<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986), Aebischer, P., et al.: Nat. Med., 2, 696 (1996), Prakash, S., et al.: Biotechnol. Bioeng., 46, 621 (1995),<br></p>Formule :CD4N2OCouleur et forme :NeatMasse moléculaire :64.08(+)-9-deMe-DTBZ
CAS :<p>Applications (+)-9-deMe-DTBZ is a desmethyl derivative of Tetrabenzine (T284000), a dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Formule :C18H27NO3Couleur et forme :NeatMasse moléculaire :305.41rac-Clopidogrel Carboxylic Acid Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications rac-Clopidogrel Carboxylic Acid Hydrochloride is a salt metabolite of rac-Clopidogrel.<br></p>Formule :C15H15Cl2NO2SCouleur et forme :NeatMasse moléculaire :344.263-Descyano Febuxostat Ethyl Ester
CAS :Produit contrôlé<p>Applications 3-Descyano Febuxostat Ethyl Ester is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formule :C17H21NO3SCouleur et forme :NeatMasse moléculaire :319.42Tenofovir Bis(L-alanine Isopropyl Ester) Amide
CAS :Produit contrôléFormule :C21H36N7O6PCouleur et forme :NeatMasse moléculaire :513.53Methotrexate Hexaglutamate Trifluoroacetate
CAS :<p>Stability Hygroscopic<br>Applications Methotrexate Hexaglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formule :C45H57N13O20·x(C2HF3O2)Couleur et forme :Yellow SolidMasse moléculaire :1214.03N10-Monodesmethyl Rizatriptan
CAS :Produit contrôlé<p>Impurity Rizatriptan EP Impurity I<br>Applications N10-Monodesmethyl Rizatriptan (Rizatriptan EP Impurity I) is a metabolite of Rizatriptan.<br>References Dechant, K., et al.: Drugs, 43, 776 (1992), Castro, J., et al.: Bioorg. Med. Chem. Lett., 3, 993 (1993), Lee, Y., et al.: Biopharm. Drug Dispos., 19, 577 (1998), Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004),<br></p>Formule :C14H17N5Couleur et forme :NeatMasse moléculaire :255.32Pemetrexed Disodium Heptahydrate
CAS :Produit contrôlé<p>Applications Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formule :C20H19N5O6·2Na·7H2OCouleur et forme :NeatMasse moléculaire :597.48N-Sulfamoylethyl Naratriptan Pyridinium Chloride
CAS :Produit contrôlé<p>Impurity Naratriptan Impurity F<br>Stability Hygroscopic<br>Applications 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium Chloride is an impurity of Naratriptan (N378730).<br></p>Formule :C20H27ClN4O4S2Couleur et forme :NeatMasse moléculaire :487.04Tenofovir Dimer Triethylammonium Salt
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications Tenofovir Dimer is a dimer of Tenofovir (T018500). Tenofovir is a reverse transcriptase inhibitor. Used as an anti-HIV agent.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formule :C30H56N12O7P2Couleur et forme :NeatMasse moléculaire :758.795-Aminoimidazole-4-carboxamide-13C2,15N Hydrochloride Salt
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Formule :C2C2H615NN3O·HClCouleur et forme :BrownMasse moléculaire :165.556Descarboxyl Febuxostat
CAS :Produit contrôléFormule :C15H16N2OSCouleur et forme :NeatMasse moléculaire :272.371-Bromoethyl Acetate (~90%)
CAS :Produit contrôlé<p>Applications 1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of antibiotics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zakrzewski, J. et al.: Pol. J. Chem. Technol., 8, 83 (2006); Kamachi, H. et al.: J. Antibiot., 41, 1602 (1988);<br></p>Formule :C4H7BrO2Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :167.0Alphenal
CAS :Produit contrôlé<p>Applications Barbituric Acid (B118650) derivative with anti-convulsive properties. Controlled Substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carissime, M. et al.: Farmac. Edi. Sci., 17, 390 (1962); Harvey, D.J. et al.: Drug. Metab. Disp., 5, 527 (1977);<br></p>Formule :C13H12N2O3Couleur et forme :NeatMasse moléculaire :244.251-(6-Amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide
CAS :Produit contrôléFormule :C10H10N8OCouleur et forme :NeatMasse moléculaire :258.24Lestaurtinib
CAS :Produit contrôlé<p>Stability Photosensitive<br>Applications It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML).<br></p>Formule :C26H21N3O4Couleur et forme :NeatMasse moléculaire :439.46Methotrexate-d3 (Technical Grade) (100ug/mL in Methanol with 1% 0.1N NaOH)
CAS :Produit contrôléFormule :C20H19D3N8O5Couleur et forme :Single SolutionMasse moléculaire :457.46Tetrabenazine
CAS :Produit contrôlé<p>Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.<br>References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),<br></p>Formule :C19H27NO3Couleur et forme :NeatMasse moléculaire :317.424-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide
CAS :Produit contrôlé<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 4-[2-(4-Chlorobutylidene)hydrazinyl]-N-methylbenzenemethanesulfonamide is an intermediate in the synthesis of 3-(2-Aminoethyl)-N-methyl-1H-indole-5-methanesulfonamide (Didesmethyl Sumatriptan) (Sumatriptan EP Impurity E) (A609165), which is an antimigraine agent. A Sumatriptan intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C12H18ClN3O2SCouleur et forme :NeatMasse moléculaire :303.81Tenofovir (1 mg/mL in Water)
CAS :Formule :C9H14N5O4PCouleur et forme :Single SolutionMasse moléculaire :287.21(1R,5R,6R)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic Acid Ethyl Ester
CAS :Produit contrôlé<p>Applications This compound is an isomer of compound (E925685) used in the synthesis of neuraminidase inhibitors.<br>References Jarinrat K. et al.: Bioorg. Med. Chem. Lett., 20, 2152 (2012);<br></p>Formule :C14H22O4Couleur et forme :NeatMasse moléculaire :254.32Thiamine Thiocarbamate
CAS :Produit contrôlé<p>Applications Thiamine (T344185) impurity.<br></p>Formule :C14H20N4O3S2Couleur et forme :NeatMasse moléculaire :356.461-(3-(2-(Dimethylamino)ethyl)-1-((5-((N-methylsulfamoyl)methyl)-1H-indol-3-yl)methyl)-1H-indol-5-yl)-N-methylmethanesulfonamide Formate Salt
CAS :Produit contrôléFormule :C25H33N5O4S2·CH2O2Couleur et forme :NeatMasse moléculaire :531.694603Valbenazine (~90% Purity)
CAS :Produit contrôlé<p>Applications Valbenzine is a highly selective vesicular monoamine transporter 2 inhibitor. It is used in the treatment of tardive dykinesia.<br>References O'Brien, C. et al.: Movement Dis., 30, 1681 (2015);<br></p>Formule :C24H38N2O4Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :418.57N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid
CAS :Produit contrôlé<p>Applications N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid, referred to as Pemetrexed, is used in the treatment of malignant pleural mesothelioma (MPM).<br>References Pasello, G. et al.: Anticanc. Res., 32, 5393 (2012);<br></p>Formule :C20H21N5O6Couleur et forme :NeatMasse moléculaire :427.41cis (2,3)-Dihydro Tetrabenazine
CAS :Produit contrôlé<p>Applications A metabolite of Tetrabenazine in vivo, which is likely the active pharmacological agent. The cis isomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.<br>References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),<br></p>Formule :C19H29NO3Couleur et forme :NeatMasse moléculaire :319.442-Pyrimidinemethanamine
CAS :Produit contrôlé<p>Applications 2-Pyrimidinemethanamine (cas# 75985-45-4) is a useful research chemical.<br></p>Formule :C5H7N3Couleur et forme :NeatMasse moléculaire :109.13Febuxostat 67M-2
CAS :Produit contrôlé<p>Applications Febuxostat 67M-2 is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation.<br>References Du, J., et al.: Handbook of Metabolic Pathways of Xenobiotics, 4, 1395 (2014)<br></p>Formule :C16H16N2O4SCouleur et forme :NeatMasse moléculaire :332.37p-Chlorophenylcyanoguanidine
CAS :Produit contrôlé<p>Impurity Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine)<br>Applications Halo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).<br>References Warner, V. et al.: J. Pharmac. Sci., 66, 418 (1977); Das, A. et al.: Ind. Drugs, 20, 19 (1980);<br></p>Formule :C8H7ClN4Couleur et forme :NeatMasse moléculaire :194.62Caffeine-D10
CAS :Produit contrôlé<p>Applications Caffeine-D10 is the labeled compound of Caffeine(C080100). Caffeine (Pentoxifylline EP Impurity F) is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor (1,2,3). Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses. Caffeine is a non-competitive inhibitor of acetylcholinesterase (3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Formule :C8D10N4O2Couleur et forme :NeatMasse moléculaire :204.252-Hydroxy-N-(pyridin-4-yl)butanamide
CAS :Produit contrôlé<p>Applications 2-Hydroxy-N-(pyridin-4-yl)butanamide is a useful synthetic intermediate.<br></p>Formule :C9H12N2O2Couleur et forme :NeatMasse moléculaire :180.2Picolinamide
CAS :Produit contrôlé<p>Applications A nicotinic acid derivative for prevention and treatment of cancer by activating RUNX3 gene.<br>References Ludwig, et al.: Cancer Res., 50, 2470 (1990), Gupta., et al.: Biomed. Environ. Sci., 13,122 (2000), Cai., et al.: J. Med. Chem., 46, 2474 (2003),<br></p>Formule :C6H6N2OCouleur et forme :NeatMasse moléculaire :122.12Methotrexate-d3 Pentaglutamate Trifluoroacetate (>90%)
CAS :Produit contrôlé<p>Applications Methotrexate-d3 Pentaglutamate is the isotope labelled analog of Methotrexate Pentaglutamate (M260735); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formule :C40H47D3N12O17(C2HF3O2)xCouleur et forme :NeatMasse moléculaire :973.91Mono-POC Tenofovir 6-Isopropyl Carbamate (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Very Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formule :C18H28N5O9PCouleur et forme :White SolidMasse moléculaire :489.42(R)- 3-[(1-Methyl-2-pyrrolidinyl)methyl]-1H-Indole
CAS :Produit contrôléFormule :C14H18N2Couleur et forme :NeatMasse moléculaire :214.31D-Alanine Isopropyl Ester Hydrochloride
CAS :Produit contrôlé<p>Applications D-Alanine Isopropyl Ester Hydrochloride is a chiral reagent used in the synthesis of nucleotide prodrugs such as (PSI-7977) for the treatment of hepatitis C. Also used in the preparation of synthetic sweeteners.<br>References Sofia, M. et al.: J. Med. Chem., 53, 7202 (2010); Mazur, R. et al.: J. Med. Chem., 16, 1284 (1973);<br></p>Formule :C6H14ClNO2Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :167.635-Carboxy-2'-deoxyuridine
CAS :Produit contrôlé<p>Applications 5-Carboxy-2'-deoxyuridine, is a derivative of Trifluridine, an anti-herpesvirus antiviral drug, used primarily on the eye.<br>References Kuster, P., et al.: CLAO J. 24(2), 122 (1998); O’Brien, W., Invest. Opthalmol. Vis. Sci., 32 (9), 2455 (1991);<br></p>Formule :C10H12N2O7Couleur et forme :NeatMasse moléculaire :272.215-[1-(2-Chlorophenyl)-2-methoxy-2-oxoethyl]-6,7-dihydrothieno[3,2-c]pyridiniumBromide (~90%)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications One of the unknown impurities generated during the accelerated stability storage of Clopidogrel bisulfate tablets. Clopidogrel impurity.<br>References Gomez, Y., et al.: J. Pharm. Biomed. Anal., 34, 341 (2004), Ksycinska, H., et al.: J. Pharm. Biomed. Anal., 41, 533 (2006),<br></p>Formule :C16H15ClNO2S·BrDegré de pureté :~90%Couleur et forme :NeatMasse moléculaire :400.726-Oxo-(S,S)-Palonosetron (~90%)
CAS :Produit contrôlé<p>Applications 6-Oxo-(S,S)-Palonosetron is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.<br>References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),<br></p>Formule :C19H22N2O2Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :310.39Benzofuran-6-carboxylic Acid
CAS :Produit contrôlé<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Formule :C9H6O3Couleur et forme :NeatMasse moléculaire :162.144-Hydroxy-1,3-benzenedicarbonitrile
CAS :Produit contrôlé<p>Applications 4-Hydroxy-1,3-benzenedicarbonitrile is used in the preparation of febuxostat (F229000), a non-purine xanthine oxidase inhibitor used as a treatment for hyperuricaemia and chronic gout.<br>References Smith, C.J., et al.: Bioorg. Med. Chem. Lett., 20, 346 (2010); Cramp. S., et al.: BIoorg. Med. Chem. Lett., 20, 2516 (2010); Sato, T., et al.: Bioorg. Med. Chem. Lett., 19, 184 (2009);<br></p>Formule :C8H4N2OCouleur et forme :NeatMasse moléculaire :144.135-Amino-4-pyrazolecarboxamide
CAS :Produit contrôléFormule :C4H6N4OCouleur et forme :Off White To Light BrownMasse moléculaire :126.117(R)-Methotrexate-d3 (Technincal Grade)
CAS :Produit contrôléFormule :C20H19D3N8O5Couleur et forme :NeatMasse moléculaire :457.46Glycylglycyl-L-tyrosine
CAS :<p>Applications Fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>Formule :C13H17N3O5Couleur et forme :NeatMasse moléculaire :295.29122-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS :Produit contrôlé<p>Applications 2-Chloro-6-amino-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (cas# 79999-39-6) is a compound useful in organic synthesis.<br></p>Formule :C16H18ClN5O7Couleur et forme :NeatMasse moléculaire :427.80Febuxostat Acyl-β-D-glucuronide
CAS :<p>Applications A metabolite of Febuxostat (F229000), a novel nonpurine selective inhibitor of Xanthin Oxidase.<br>References Grabowski, B., et al.: J. Clin. Pharmacol., 51, 189 (2011); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formule :C22H24N2O9SCouleur et forme :Off White PowderMasse moléculaire :492.50Regadenoson-d3
CAS :Produit contrôlé<p>Applications A selective A2A adenosine receptor agonist in myocardial imaging.<br>References Palle, V.P., et al.: J. A. Drug Dev. Res., 50, 64 (2000), Gordi, T., et al.: J. Clin. Pharmacol., 47, 825 (2007), Zhao, G., et al.: J. Cardiovas. Pharmacol., 52, 467 (2008), Botvinick, E., et al.: J. Nuc. Med. Technol., 37, 14 (2009),<br></p>Formule :C15H15D3N8O5Couleur et forme :NeatMasse moléculaire :393.37Chloroformic Acid Chloromethyl Ester
CAS :Produit contrôlé<p>Stability Very Very Moisture sensitive<br>Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);<br></p>Formule :C2H2Cl2O2Couleur et forme :Colourless OilyMasse moléculaire :128.94m-Hydroxyhippuric Acid-13C2, 15N
CAS :<p>Applications m-Hydroxyhippuric Acid-13C2, 15N is labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human.<br>References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)<br></p>Formule :C713C2H915NO4Couleur et forme :White To Off-WhiteMasse moléculaire :198.15Almotriptan-d6 Hydrochloride
CAS :Produit contrôlé<p>Applications: Labelled Almotriptan (A575200). Almotriptan is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.<br>References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)<br></p>Formule :C172H6H19N3O2S·ClHCouleur et forme :NeatMasse moléculaire :377.962,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Methotrexate intermediate.<br>References Feng, Y., et al.: J. Med. Chem., 49, 770 (2006),<br></p>Formule :C7H8N6O·ClHCouleur et forme :YellowMasse moléculaire :228.64Sumatriptan Hydroxy-Oxindole Impurity (Sumatriptan Impurity 1)
CAS :Produit contrôlé<p>Applications Sumatriptan Impurity 1, is an impurity of Sumatriptan (S810000), which is a serotonin 5HT1-receptor agonist, used for the treatment of migraine headaches.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988), Doenicke, A., et al.: Lancet 1, 1309 (1988),<br></p>Formule :C14H21N3O4SCouleur et forme :NeatMasse moléculaire :327.4N-(5-Aminopentyl) Methotrexate Amide
CAS :Produit contrôlé<p>Applications The 5-aminopentyl amide derivative of the folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Fan, J. et al.: J. Biol. Chem., 266, 14862 (1991);<br></p>Formule :C25H34N10O4Couleur et forme :NeatMasse moléculaire :538.6Caffeine Citrate
CAS :<p>Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);<br></p>Formule :C8H10N4O2·C6H8O7Couleur et forme :WhiteMasse moléculaire :386.31Allopurinol impurity E
CAS :<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Formule :C7H9N3O3Degré de pureté :Min. 95%Masse moléculaire :183.16 g/molMethotrexate-5-monomethyl ester
CAS :<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Formule :C21H24N8O5Degré de pureté :Min. 95%Masse moléculaire :468.47 g/molPemetrexed impurity C
CAS :<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Formule :C40H40N10O13Degré de pureté :Min. 95%Masse moléculaire :868.81 g/mol1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS :<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Formule :C8H9NO2Degré de pureté :Min. 95%Masse moléculaire :151.16 g/mol2,4-Diamino-7-pteridinemethanol
CAS :<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Formule :C7H8N6ODegré de pureté :Min. 95%Masse moléculaire :192.18 g/molZolmitriptan related compound D
CAS :<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Formule :C19H25N3O4Degré de pureté :Min. 95%Masse moléculaire :359.42 g/molAllopurinol Sodium
CAS :<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formule :C5H4N4NaODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :159.13,4-Dihydro naratriptan
CAS :<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Formule :C17H23N3O2SDegré de pureté :Min. 95%Masse moléculaire :333.45 g/molMercaptopurine impurity standard
CAS :<p>Mercaptopurine impurity standard is a drug product that is used as an analytical reference standard in the development of drugs. Mercaptopurine impurity standard is a natural metabolite of 6-mercaptopurine, which is used to treat leukemia and other forms of cancer. It has been shown to have an anti-inflammatory effect, but this has not been confirmed. Mercaptopurine impurity standard is a synthetic compound that is made synthetically for use as an impurity standard. It has also been shown to be metabolized by cytochrome P450 enzymes, glutathione reductase, or conjugation with glucuronic acid. Mercaptopurine impurity standard has been shown to be stable under acidic conditions and heat treatment at temperatures up to 200°C.</p>Degré de pureté :Min. 95%Lysine-methotrexate
CAS :<p>Lysine-methotrexate is a monoclonal antibody that binds to the DNA template of Leishmania. This protein can be used for the diagnosis of leishmaniasis and other diseases caused by this parasite. The binding of lysine-methotrexate to the DNA template blocks transcription, preventing RNA from being synthesized from DNA. Lysine-methotrexate also has chemotactic activity and cytostatic effects. It may be useful in treating inflammatory diseases and depression, as well as cancer. Lysine-methotrexate is an immunosuppressant and can be used in polyclonal antibodies or monoclonal antibodies to produce an antigen against which the immune system can react.</p>Formule :C21H27N9O3Degré de pureté :Min. 95%Masse moléculaire :453.5 g/mol(S)-Tenofovir
CAS :<p>(S)-Tenofovir ((S)-PMPA) is the less active S-enantiomer of Tenofovir which is a nucleotide reverse transcriptase inhibitor.</p>Formule :C9H14N5O4PDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :287.214-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS :<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C20H27N4O4S2•ClDegré de pureté :Min. 95%Masse moléculaire :487.04 g/molClopidogrel Impurity A
CAS :<p>Clopidogrel Impurity A is a medicine that is used for the prevention of heart attacks, strokes, and blood clots in people with an increased risk of these events. It is not intended to be used for immediate relief from sudden symptoms. Clopidogrel Impurity A is a substance that may be found in some preparations of clopidogrel. The presence of this substance can be detected by liquid chromatography-mass spectrometry (LC-MS/MS) methods. The structural analysis of this substance was determined using enantiomeric resolution and chromatographic methods. This impurity has been shown to have no effect on the bioavailability of the parent drug, clopidogrel, when given orally to Sprague-Dawley rats.</p>Formule :C15H15Cl2NO2SDegré de pureté :Min. 95%Masse moléculaire :344.26 g/mol5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide
CAS :<p>5-[(Hydroxyacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a drug product that was synthesized for research purposes. It is an analytical standard for HPLC and has not been approved for clinical use. 5-[(Hydroxylacetyl)amino]-N,N'-bis [2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide is a compound with natural origin and has been classified as an API impurity. This synthetic drug product is custom synthesized to meet the requirements of pharmacopoeia standards.</p>Formule :C16H20I3N3O8Degré de pureté :Min. 95%Masse moléculaire :763.06 g/mol3-(Formylamino)-1H-pyrazole-4-carboxamide
CAS :<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>Formule :C5H6N4O2Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :154.13 g/molMeropenem EP Impurity A
<p>Meropenem EP Impurity A is a synthetic, high purity, drug product that is used as an impurity standard for Meropenem. It has been synthesized from a custom synthesis and is available in both natural and synthetic form. This impurity can be used to investigate the metabolism of Meropenem and to determine its stability in different environments. The HPLC analysis of this impurity is available as a pharmacopoeia standard.</p>Formule :C17H27N3O6SDegré de pureté :Min. 95%Masse moléculaire :401.48 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS :<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Formule :C14H18I3N3O6Degré de pureté :Min. 95%Masse moléculaire :705.02 g/molAllopurinol impurity A
CAS :<p>Allopurinol is an anticancer drug that is used to treat leukemia and other cancers. Allopurinol impurity A is a byproduct of the production of allopurinol, which has been shown to have anticancer properties. It has been shown to suppress the expression of suppressor genes and up-regulated genes in pancreatic cancer cells. This compound also induces apoptosis in orthotopic liver cells in a process involving activation of caspase 3 and suppression of Akt signaling.</p>Degré de pureté :Min. 95%Tenofovir diphosphate
CAS :<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Formule :C9H16N5O10P3Couleur et forme :SolidMasse moléculaire :447.17Ormetoprim
CAS :<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Formule :C14H18N4O2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :274.32Tenofovir exalidex
CAS :<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Formule :C28H52N5O5PDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :569.72Neopterin
CAS :<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Formule :C9H11N5O4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :253.21OXSI-2
CAS :<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formule :C18H15N3O3SDegré de pureté :98%Couleur et forme :Dark Orange SolidMasse moléculaire :353.39Migalastat
CAS :<p>Migalastat (GR181413A free base) is an orally administered, competitive inhibitor of α-galactosidase A (α-Gal A), demonstrating an IC50 value of 0.04 μM against</p>Formule :C6H13NO4Couleur et forme :SolidMasse moléculaire :163.17Palonosetron
CAS :<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Formule :C19H24N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.41Clopidogrel EP Impurity B hydrochloride
CAS :<p>Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C16H16ClNO2S•HClDegré de pureté :Min. 95%Masse moléculaire :358.28 g/molButalbital CIII
CAS :Produit contrôlé<p>Allobarbital (inn), amobarbital (inn), barbital (inn), butalbital (inn), butobarbital, cyclobarbital(inn), methylphenobarbital (inn), etc.</p>Formule :C11H16N2O3Couleur et forme :White PowderMasse moléculaire :224.11609Codeine Phosphate CII
CAS :Produit contrôlé<p>Concentrates of poppy straw; buprenorphine (inn) codein</p>Formule :C18H21NO3·H3O4PH2OCouleur et forme :White Crystalline PowderMasse moléculaire :406.37 g/molErgotamine Tartrate
CAS :Produit contrôlé<p>Ergotamine and its salts</p>Formule :(C33H35N5O5)2·C4H6O6Couleur et forme :White Yellow PowderMasse moléculaire :1162.52764N-Hydroxymethyl Sumatriptan
CAS :<p>N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).</p>Formule :C15H23N3O3SDegré de pureté :Min. 95%Masse moléculaire :325.43 g/mol1-Bromo-3,5-dimethyladamantane
CAS :<p>Intermediate in the synthesis of memantine</p>Formule :C12H19BrDegré de pureté :Min. 95%Masse moléculaire :243.18 g/molN-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-L-glutamic acid
CAS :<p>N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-gamma-glutamyl-L-glutamic acid is used as a research and development purity standard. It is a white crystalline powder that is soluble in water and ethanol. N-[4-[2-(2Amino 4,7dihydro 4oxo 3Hpyrrolo 2,3d]pyrimidin 5yl)ethyl]benzoyl]-L gamma glutamyl L glutamic acid has CAS number 144051 68 3. The drug product is a synthetic compound with high purity. It has been shown to be an analytical reference substance for HPLC standards and to have niche applications in metabolism studies of other drugs.</p>Formule :C25H28N6O9Degré de pureté :Min. 95%Masse moléculaire :556.52 g/molMethotrexate-1-monomethyl ester
CAS :<p>Methotrexate-1-monomethyl ester is an impurity found in methotrexate, a drug used to treat cancer and autoimmune disorders. Methotrexate-1-monomethyl ester is a white to off-white crystalline solid that has been synthesized as a custom synthesis. It is used as an analytical standard for the determination of methotrexate in biological fluids and tissues. The chemical purity of this compound can be determined by HPLC, which allows for the identification of any impurities that may be present. Methotrexate-1-monomethyl ester is also used as a pharmacopoeia standard for methotrexate and its metabolites.</p>Formule :C21H24N8O5Degré de pureté :Min. 95%Masse moléculaire :468.47 g/molSumatriptan EP Impurity A
CAS :<p>Sumatriptan EP Impurity A is a metabolite of sumatriptan, a drug product that is used for the treatment of migraine headaches. Sumatriptan EP Impurity A is a natural metabolite of sumatriptan and has been found to be an analytical impurity in the drug product. It has been shown to have anti-inflammatory properties and may be useful for treating arthritis. This impurity can also be synthesized by chemical synthesis or recombinant DNA technology.</p>Formule :C27H37N5O2SDegré de pureté :Min. 95%Masse moléculaire :495.68 g/molFrovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.3PF 184
CAS :<p>IKKβ inhibitor</p>Formule :C32H32ClFN6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :619.09Miglustat hydrochloride
CAS :<p>Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher</p>Formule :C10H22ClNO4Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :255.74Sumatriptan 3-hydroxy-2-oxo impurity
CAS :<p>Please enquire for more information about Sumatriptan 3-hydroxy-2-oxo impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C14H21N3O4SDegré de pureté :Min. 95%Masse moléculaire :327.4 g/molSorivudine
CAS :<p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>Formule :C11H13BrN2O6Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :349.13Porphobilinogen
CAS :<p>Porphobilinogen act as a phytotoxin, a metabotoxin, and a neurotoxin.</p>Formule :C10H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.23MRS2500
CAS :<p>MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.</p>Formule :C13H18IN5O8P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.161-Benzyl-5-phenylbarbituric acid, 98+%
CAS :<p>1-Benzyl-5-phenylbarbituric acid is useful as a pharmaceutical intermediate in organic synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar p</p>Formule :C17H14N2O3Degré de pureté :98+%Couleur et forme :Powder, White to creamMasse moléculaire :294.31Open Ring N-Methyl Clopidogrel Hydrochloride (methyl (S)-2-(2-chlorophenyl)-2-(methyl(2-(thiophen-2-yl)ethyl)amino)acetate, hydrochloride) (DISCONTINUED)
CAS :<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Formule :C16H18ClNO2S·HClCouleur et forme :White Off-White SolidMasse moléculaire :359.05136Ergotaminine
CAS :<p>Alkaloids of rye ergot and their derivatives; salts thereof, nesoi</p>Formule :C33H35N5O5Couleur et forme :White Off-White Light Grey Crystalline PowderMasse moléculaire :581.26382Diamino-L-Tyrosine
CAS :Formule :C9H13N3O3Couleur et forme :White To Off-White SolidMasse moléculaire :211.22
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