Dérivés des Purines et Pyrimidines
Les purines possèdent une structure bicyclique, composée d’un cycle à six membres fusionné avec un cycle à cinq membres, tous deux contenant des atomes d’azote à des positions clés. Les dérivés des purines, tels que l’adénine et la guanine, sont essentiels à la formation de l’ADN et de l’ARN. Ces composés ont des applications thérapeutiques dans le traitement du cancer et des maladies virales en inhibant la réplication cellulaire. Les pyrimidines, quant à elles, possèdent une structure monocyclique à six membres avec deux atomes d’azote. Leurs dérivés, tels que la cytosine, la thymine et l’uracile, sont également des composants essentiels de l’ADN et de l’ARN et sont utilisés en chimiothérapie et dans les traitements antiviraux.
Chez CymitQuimica, nous proposons des dérivés des purines et pyrimidines pour la recherche en biologie moléculaire, génomique et le développement de thérapies innovantes.
8892 produits trouvés pour "Dérivés des Purines et Pyrimidines"
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PTP inhibitor 1
CAS :<p>PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the SHP-1(ΔSH2).</p>Formule :C9H9BrO2Degré de pureté :99.51%Couleur et forme :Light Brown PowderMasse moléculaire :229.07Memantine
CAS :<p>Memantine treats moderate to severe Alzheimer's; it's an amantadine derivative blocking NMDA receptors.</p>Formule :C12H21NDegré de pureté :≥98%Couleur et forme :White PowderMasse moléculaire :179.3TAK-659 hydrochloride
CAS :<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Formule :C17H22ClFN6ODegré de pureté :99.28% - 99.82%Couleur et forme :SolidMasse moléculaire :380.85PTEROIC ACID
CAS :<p>Pteroic acid is part of the structure of folic acid</p>Formule :C14H12N6O3Degré de pureté :96.4% - >99.99%Couleur et forme :SolidMasse moléculaire :312.28Rizatriptan benzoate
CAS :<p>Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine</p>Formule :C22H25N5O2Degré de pureté :99% - 99.79%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :391.47MGCD-265 analog
CAS :<p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>Formule :C26H20FN5O2S2Degré de pureté :98.06% - 98.68%Couleur et forme :SolidMasse moléculaire :517.6AMG-47a
CAS :<p>AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.</p>Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56Ondansetron hydrochloride
CAS :<p>Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation</p>Formule :C18H19N3O·HClDegré de pureté :99.78%Couleur et forme :White PowderMasse moléculaire :329.82Deoxycytidine triphosphate trisodium salt
CAS :<p>Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.</p>Formule :C9H13N3Na3O13P3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :533.1Sitravatinib
CAS :<p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>Formule :C33H29F2N5O4SDegré de pureté :98.9% - 99.85%Couleur et forme :SolidMasse moléculaire :629.68N1-Nitroso Theophylline (N1-Nitroso Dimenhydrinate EP Impurity A, N1-Nitroso Diprophylline EP Impurity B)
Formule :C7H7N5O3Masse moléculaire :209.173, 3'-Diiodo-L-Thyronine-(Phenoxy-13C6)
CAS :Formule :C913C6H13I2NO4·HClMasse moléculaire :531.04 36.46Succinimidyl 2-(3-((Benzyloxy)Carbonyl)-1-Methyl-5-Oxoimidazolidin-4-yl-Acetate
Formule :C18H19N3O7Masse moléculaire :389.36Nicotinamide N-oxide
CAS :<p>Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.</p>Formule :C6H6N2O2Degré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :138.12Cardiogenol C hydrochloride
CAS :<p>Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).</p>Formule :C13H17ClN4O2Degré de pureté :99.89% - 99.94%Couleur et forme :SolidMasse moléculaire :296.75Methotrexate EP Impurity C (Methotrexate USP Related Compound C)
CAS :Formule :C20H21N7O6Masse moléculaire :455.43Bohemine
CAS :<p>Bohemine is a cyclin-dependent kinase inhibitor.</p>Formule :C18H24N6ODegré de pureté :99.09% - 99.53%Couleur et forme :SolidMasse moléculaire :340.42rac-Tenofovir Disoproxil Related Compound G Fumarate
Formule :C17H28N5O7PC4H4O4Masse moléculaire :445.42 116.07Sulbutiamine
CAS :<p>Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.</p>Formule :C32H46N8O6S2Degré de pureté :99.18% - 99.47%Couleur et forme :White - Almost White Crystal - PowderMasse moléculaire :702.89Orotic acid zinc
CAS :<p>Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis.</p>Formule :C10H6N4O8ZnDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :188.79Furafylline
CAS :<p>Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 μM),</p>Formule :C12H12N4O3Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :260.25Lorlatinib
CAS :<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Formule :C21H19FN6O2Degré de pureté :99.77% - 99.95%Couleur et forme :SolidMasse moléculaire :406.41SU4984
CAS :<p>SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).</p>Formule :C20H19N3O2Degré de pureté :97.20%Couleur et forme :SolidMasse moléculaire :333.38Xanthosine 5'-monophosphate sodium salt
CAS :<p>Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism.</p>Formule :C10H11N4Na2O9PDegré de pureté :99% - 99.77%Couleur et forme :SolidMasse moléculaire :408.17Regadenoson hydrate
CAS :<p>Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.</p>Formule :C15H20N8O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.37Ro 61-8048
CAS :<p>Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM.</p>Formule :C17H15N3O6S2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :421.45Ecamsule
CAS :<p>Ecamsule, a stable benzylidene camphor derivative, is an organic UVA filter in sunscreens.</p>Formule :C28H34O8S2Degré de pureté :99.2%Couleur et forme :Solid PowderMasse moléculaire :562.69O6-Benzylguanine
CAS :<p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>Formule :C12H11N5ODegré de pureté :98.9%Couleur et forme :Solid CrystallineMasse moléculaire :241.25Idelalisib
CAS :<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42SB-332235 (6-Chloro-3-[3-(2,3-dichlorophenyl)ureido]-2-hydroxybenzenesulfonamide)
CAS :Formule :C13H10Cl3N3O4SMasse moléculaire :410.67LM10
CAS :<p>TDO inhibitor; IC50: human 0.62 μM, mouse 2 μM; selective over IDO, MAOs; hinders TDO+ tumor growth in mice; orally active.</p>Formule :C11H8FN5Degré de pureté :98.78% - 99.94%Couleur et forme :SolidMasse moléculaire :229.21Dovitinib lactate hydrate
CAS :<p>Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).</p>Formule :C24H27FN6O4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :482.51Purine
CAS :<p>Purine: an aromatic compound with fused pyrimidine & imidazole rings, turned into uric acid by enzymes; excessive uric acid can lead to gout.</p>Formule :C5H4N4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :120.11Methotrexate EP Impurity E-13C-d3 (Methotrexate USP Related Compound E-13C-d3)
Formule :C1413CH12D3N7O2Masse moléculaire :329.34Pyrimidine
CAS :<p>Pyrimidines are essential RNA/DNA bases (uracil, cytosine, thymine) involved in genetic encoding and various metabolic processes.</p>Formule :C4H4N2Degré de pureté :99.85%Couleur et forme :LiquidMasse moléculaire :80.09Oseltamivir-Glucose Adduct 2 (Amadori Rearrangement Product)
Formule :C22H38N2O9Masse moléculaire :474.55Bendamustine
CAS :<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Formule :C16H21Cl2N3O2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :358.26AG957
CAS :<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Formule :C15H15NO4Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :273.28Adenine hemisulfate
CAS :<p>Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry</p>Formule :(C5H5N5)·H2SO4Degré de pureté :99.48%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :368.33AZD-3463
CAS :<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95Pyridoxylamine dihydrochloride
CAS :<p>Pyridoxylamine dihydrochloride (Pyridorin) is a hydrochloride salt of one form of vitamin B6.</p>Formule :C8H14Cl2N2O2Degré de pureté :99.44%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :241.12L-Phenylalanine
CAS :<p>L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.</p>Formule :C9H11NO2Degré de pureté :99.37% - 99.87%Couleur et forme :Solid CrystallineMasse moléculaire :165.19Guanine
CAS :<p>Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids.</p>Formule :C5H5N5ODegré de pureté :99.89%Couleur et forme :Several Desmotropic Forms; Usually Amorphous SolidMasse moléculaire :151.13Ioxitalamic Acid
CAS :<p>Ioxitalamic Acid (Acidum Joxitalamicum) is a medical contrast medium and enhances the contrast of structures or fluids in the body in medical imaging.</p>Formule :C12H11I3N2O5Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :643.94lavendustin C
CAS :<p>lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.</p>Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Tolebrutinib
CAS :<p>Tolebrutinib is an oral, selective BTK inhibitor, effective for MS research, with brain penetration and IC50s of 0.4/0.7 nM in cells.</p>Formule :C26H25N5O3Degré de pureté :98.4% - 98.82%Couleur et forme :SolidMasse moléculaire :455.51Rifamycin S
CAS :<p>Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria</p>Formule :C37H45NO12Degré de pureté :98.74%Couleur et forme :Yellow Orange Crystalline PowderMasse moléculaire :695.75Thymine
CAS :<p>Thymine: Derived from DNA hydrolysis or methylcyanoacetylurea, found in DNA (not RNA), binds adenine, used in biochemical research.</p>Formule :C5H6N2O2Degré de pureté :99.77% - 99.97%Couleur et forme :SolidMasse moléculaire :126.11PD-161570
CAS :<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Formule :C26H35Cl2N7ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :532.51PI3Kδ-IN-15
CAS :<p>CAL-101 (Idelalisib) is a selective inhibitor of p110δ; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ.</p>Formule :C21H16FN7ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :401.4Almotriptan
CAS :<p>Almotriptan (LAS 31416), a triptan and 5-HT1B/1D agonist, treats migraines by constricting cranial vessels and altering blood flow.</p>Formule :C17H25N3O2SDegré de pureté :99.85%Couleur et forme :Light Yellow Or White PowerMasse moléculaire :335.46trans-Zeatin
CAS :<p>trans-Zeatin ((E)-Zeatin) is the member of the plant growth hormone family known as cytokinins, which regulate cell division, development, and nutrient</p>Formule :C10H13N5ODegré de pureté :97.13% - 98.96%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :219.24Pentostatin
CAS :<p>Pentostatin (CI-825) is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM).</p>Formule :C11H16N4O4Degré de pureté :99.57% - 99.89%Couleur et forme :White CrystalsMasse moléculaire :268.276-Mercaptopurine hydrate
CAS :<p>6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.</p>Formule :C5H6N4OSDegré de pureté :97.54% - 99.14%Couleur et forme :Light Yellow Crystalline PowderMasse moléculaire :170.19
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