Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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N-Chloro Ethyl ThioTEPA
CAS :Produit contrôlé<p>Stability Hygroscopic, Moisture Sensitive<br>Applications N-Chloro Ethyl ThioTEPA is an impurity of ThioTEPA which is an alkylating agent used to treat cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maanen, M., et al.: Cancer Treatment Rev., 26, 257 (2000); Sykes, M., et al.: Cancer, 6, 142 (1953)<br></p>Formule :C6H13ClN3PSCouleur et forme :White To Off-WhiteMasse moléculaire :225.682-Chloro-5-(5-Chloro-2-thienyl)pyridine
CAS :Formule :C9H5Cl2NSDegré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :230.11Nimodipine
CAS :<p>Applications A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Neuroprotective & Neuroresearch products.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formule :C21H26N2O7Couleur et forme :NeatMasse moléculaire :418.44Chlorpromazine N-Oxide Maleic Acid Salt
CAS :Produit contrôlé<p>Applications Chlorpromazine N-Oxide Maleic Acid Salt is an impurity of Chlorpromazine (C424750) which has antiemetic; antipsychotic properties.<br>References Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)<br></p>Formule :C21H23ClN2O5SCouleur et forme :NeatMasse moléculaire :450.94Vismodegib
CAS :Produit contrôlé<p>Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. Potent Hedgehog inhibitor.<br>References Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)<br></p>Formule :C19H14Cl2N2O3SCouleur et forme :Off-WhiteMasse moléculaire :421.30Alogliptin-d3
CAS :Produit contrôlé<p>Applications Labelled Alogliptin (A575425). It is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.<br>References Lynn, F., et al.: Diabetes, 50, 1004 (2001), Trumper, A., et al.: J. Endocrinol., 174, 233 (2002), Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009),<br></p>Formule :C182H3H18N5O2Couleur et forme :NeatMasse moléculaire :342.41Trametinib
CAS :Produit contrôlé<p>Applications Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.<br>References Ercan, D. et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M. et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);<br></p>Formule :C26H23FIN5O4Couleur et forme :Off-WhiteMasse moléculaire :615.39Irbesartan-d4
CAS :Produit contrôlé<p>Applications Irbesartan-d4 is the labeled analogue of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998); Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008); Ren, X., et al.: Pharmacol., 83, 80 (2009)Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals<br></p>Formule :C25H24D4N6OCouleur et forme :NeatMasse moléculaire :432.55Ramelteon
CAS :Produit contrôlé<p>Applications Melatonin MT1/MT2 receptor agonist. Sedative, hypnotic.<br>References Yukuhiro, N., et al.: Brain Res., 59, 1027 (2004), Cajochen, C., et al.: Curr. Opin. Invest. Drugs, 6, 114 (2005), Kato, K., et al.: Neuropharmacology, 48, 301 (2005),<br></p>Formule :C16H21NO2Couleur et forme :NeatMasse moléculaire :259.34Desisopropyl Atrazine
CAS :Produit contrôlé<p>Applications A metabolite of Atrazine (ATR) (A794600).<br>References Compton, D., et al.: Eur. J. Pharmacol., 110, 157 (1985), Das, P., et al.: Toxicol. Sci., 59, 127 (2001), Das, P., et al.: Life Sci., 73, 3123 (2003), Coban, A., et al.: J. Neurochem., 100, 1177 (2007),<br></p>Formule :C5H8ClN5Couleur et forme :Off-WhiteMasse moléculaire :173.60(Z)-1,2-Diphenyl-1-(4-hydroxyphenyl)-1-butene (contain up to 10% E-isomer)
CAS :Produit contrôléFormule :C22H20OCouleur et forme :NeatMasse moléculaire :300.394Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
CAS :Produit contrôlé<p>Applications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.<br>References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),<br></p>Formule :C292H8H23N7O·CH4O3SCouleur et forme :NeatMasse moléculaire :597.76Felbamate-d4
CAS :Produit contrôlé<p>Applications Antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formule :C11H10D4N2O4Couleur et forme :NeatMasse moléculaire :242.2673,4-Dihydro Naratriptan Oxalate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Formule :C17H23N3O2S·C2H2O4Couleur et forme :White To Light YellowMasse moléculaire :333.45 + 90.03Tetramethylurea
CAS :<p>Applications Tetramethylurea is an excellent solvent for organic substances, in particular aromatic compounds.<br>References Lüttringhaus, A., et al.: Angew. Chem. Int. Ed. Engl., 3, 260 (1964)<br></p>Formule :C5H12N2OCouleur et forme :NeatMasse moléculaire :116.16Vildagliptin Amide
CAS :Produit contrôlé<p>Impurity Vildagliptin Amide Impurity<br>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-prolinamide is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4).<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formule :C17H27N3O3Couleur et forme :Off-WhiteMasse moléculaire :321.41Vildagliptin Carboxylic Acid Lithium Salt Hydrate
CAS :Produit contrôlé<p>Applications The major metabolite of Vildagliptin (V305000).<br>References Reimer, M.K., et al.: Eur. J. Endocrinol., 146, 717 (2002), Villhauer, E.B., et al.: J. Med. Chem., 46, 2774 (2003), Ahren, B., et al.: J. Clin. Endocrinol. Metab., 85, 2078 (2004), He, H., et al.: Drug Metab. Dispos., 37, 545 (2009),<br></p>Formule :C17H25LiN2O4Couleur et forme :NeatMasse moléculaire :328.33Nifursol (~90%)
CAS :Produit contrôlé<p>Applications A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Formule :C12H7N5O9Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :365.217-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 7-(4-Chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone is used in the synthesis of aripiprazole, an antipsychotic oral drug used in the treatment of Schizophrenia.<br>References Bonacorsi, S. et al.: J. Label. Comp. Radiopharm., 49, 1 (2006); Morita, Seiji; K. et al.: Tetrahedron, 54, 4811 (1998);<br></p>Formule :C13H16ClNO2Couleur et forme :Off-WhiteMasse moléculaire :253.723-(2-Cyanopropan-2-yl)-N-(3-((7-methoxyquinazolin-4-yl)amino)-4-methylphenyl)benzamide
CAS :Degré de pureté :97.0%Masse moléculaire :451.5299987792969Ref: 10-F544635
5mgÀ demander10mgÀ demander25mgÀ demander50mgÀ demander100mgÀ demander250mgÀ demander5-Chloro-Vortioxetine Hydrobromide
CAS :Produit contrôlé<p>Applications 5-Chloro-Vortioxetine is an impurity of Vortioxetine (V766000), a multimodal serotonergic agent. Vortioxetine inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.<br>References Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011); Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012); Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formule :C18H22BrClN2SCouleur et forme :NeatMasse moléculaire :413.82-amino-N-phenylquinoline-3-carboxamide
CAS :Degré de pureté :97%Masse moléculaire :263.299987792968756-chloro-2-(3-hydroxyphenyl)quinoline-4-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :299.70999145507814-(Phenylamino)-1-benzyl-4-piperidinecarbonitrile
CAS :Produit contrôlé<p>Applications Used as modulators of muscarinic receptors for treatment of CNS disorders.<br>References Coghlan, M., et al.: J. Med. Chem., 44, 1627 (2001), Ashcroft, F., et al.: J. Clin. Invest., 115, 2047 (2005), Bryan, J., et al.: Curr. Pharm. Des., 11, 2699 (2005),<br></p>Formule :C19H21N3Couleur et forme :NeatMasse moléculaire :291.39Methyl 4’-[[2-n-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]methyl]biphenyl-2-ca
CAS :Formule :C34H32N4O2Couleur et forme :YellowMasse moléculaire :528.64Regorafenib (Pyridine)-N-oxide
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications Regorafenib (Pyridine)-N-oxide is a synthetic metabolite of Regorafenib (R143000) and is used for treatment and prevention of cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wilhelm, S.: PCT Int. Appl. WO 2011130728 A1 20111020. Oct 20, 2011<br></p>Formule :C21H15ClF4N4O4Couleur et forme :NeatMasse moléculaire :498.81Maraviroc
CAS :Produit contrôléFormule :C29H41F2N5OCouleur et forme :White To Off-WhiteMasse moléculaire :513.67(S) FTY720 Phosphate
CAS :<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005<br></p>Formule :C19H34NO5PCouleur et forme :WhiteMasse moléculaire :387.45Desbutyl Dronedarone Hydrochloride
CAS :<p>Impurity Dronedarone USP Related Compound A<br>Applications A metabolite of Dronedarone (D679445). Dronedarone impurity D. Dronedarone USP Related Compound A.<br>References Bolderman, R.W. et al.: J Chrom. B:Anal. Tech. Biomed. Life Sci., 887, 1727 (2009); Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008); Hoy, S., et al.: Drugs, 69, 1647 (2009);<br></p>Formule :C27H36N2O5S·ClHCouleur et forme :NeatMasse moléculaire :537.11Dextrosimendan
CAS :Produit contrôlé<p>Applications Dextrosimendan is an isomer and impurity of Levosimendan (L378000), a bioactive enantiomer of Simendan (S466000). Levosimendan is a positive inotropic agent with vasodilating activity.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formule :C14H12N6OCouleur et forme :Yellow To Dark YellowMasse moléculaire :280.284-Anilino-4-oxobutanoic Acid
CAS :Produit contrôlé<p>Applications The metabolite (MII) of Suberoylanilide Hydroxamic Acid (S688700).<br>References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)<br></p>Formule :C10H11NO3Couleur et forme :NeatMasse moléculaire :193.201-(4-(Trifluoromethoxy)phenyl)-2-thiourea
CAS :Produit contrôléFormule :C8H7F3N2OSCouleur et forme :NeatMasse moléculaire :236.21N-Nitroso Nitrofurantoin impurity R
Produit contrôléFormule :C7H6N4O6Couleur et forme :NeatMasse moléculaire :242.14574Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS :Produit contrôlé<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Formule :C11H13N2O3ClCouleur et forme :NeatMasse moléculaire :256.68ent-Paroxetine Hydrochloride
CAS :Produit contrôlé<p>Impurity Paroxetine EP Impurity D; Paroxetine USP Related Compound C<br>Applications ent-Paroxetine Hydrochloride (Paroxetine EP Impurity D; Paroxetine USP Related Compound C) is an enantiomeric impurity of Paroxetine (P205750).<br>References Engelstoft, M. et al.: Acta Chem. Scand. , 50, 164 (1996);<br></p>Formule :C19H20FNO3·ClHCouleur et forme :Off-WhiteMasse moléculaire :365.83Valsartan Benzyl Ester
CAS :<p>Impurity Valsartan USP Related Compound C<br>Applications Valsartan (V095750) intermediate. Valsartan USP Related Compound C.<br>References Cramer., et al.: J. Med. Chem., 42, 3919 (1999),<br></p>Formule :C31H35N5O3Couleur et forme :NeatMasse moléculaire :525.642,2'-Dithiobis[N-methyl-benzamide]
CAS :<p>Applications Benzamide, 2,2'-dithiobis[N-methyl- (cas# 2527-58-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C16H16N2O2S2Couleur et forme :Light Yellow To Light BeigeMasse moléculaire :332.44N-Methyl Omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
CAS :Produit contrôlé<p>Applications Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formule :C18H21N3O3SCouleur et forme :Off White SolidMasse moléculaire :359.44Latrepirdine dihydrochloride
CAS :Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formule :C21H25N3·2HClDegré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :392.371-CYCLOPROPYL-6,7,8-TRIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
CAS :Degré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :283.205993652343755-Aminoimidazole-4-carboxamide
CAS :<p>Applications A metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Formule :C4H6N4OCouleur et forme :White To Off-WhiteMasse moléculaire :126.123-(4-Fluoro-phenyl)-1-methyl-1H-pyrazole-4-carbaldehyde
CAS :Formule :C11H9FN2ODegré de pureté :95.0%Couleur et forme :Solid, Light yellow powderMasse moléculaire :204.2042-(Tetrahydro-2H-pyran-4-yloxy)isonicotinic acid
CAS :Degré de pureté :97.0%Masse moléculaire :223.22799682617188(S)-Ibrutinib
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications (S)-Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References Pan, Z., et. al.: ChemMedChem, 2, 58 (2007)<br></p>Formule :C25H24N6O2Couleur et forme :NeatMasse moléculaire :440.54-Methyl-2-(1-methyl-piperidin-4-yl)-2H-pyrazol-3-ylamine
CAS :Formule :C10H18N4Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :194.2826-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
CAS :Produit contrôlé<p>Applications An Intermediate in the synthesis of risperidone and iloperidone.<br></p>Formule :C12H13FN2OCouleur et forme :NeatMasse moléculaire :220.24(S)-Naproxen
CAS :<p>Applications (S)-Naproxen is a a nonsteroidal anti-inflammatory compound with analgesic and antipyretic properties (1,2). (S)-Naproxen is also a potent COX1 inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)(2) Scott, W. W., et al.: World Neurosurg. 82, e633 (2014)<br></p>Formule :C14H14O3Couleur et forme :Off-WhiteMasse moléculaire :230.26Ethyl 5-{[1,1'-biphenyl]-4-yl}-1H-pyrazole-3-carboxylate
CAS :Degré de pureté :95.0%Masse moléculaire :292.3380126953125Quinoxyfen
CAS :Produit contrôlé<p>Applications Agricultural fungicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Corrales, M., et al.: Food Chem. Toxicol., 48, 3471 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5897 (2010),<br></p>Formule :C15H8Cl2FNOCouleur et forme :Off-WhiteMasse moléculaire :308.13Dolutegravir O-b-D-Glucuronide Sodium salt
Formule :C26H26F2N3NaO11Couleur et forme :White To Off-WhiteMasse moléculaire :617.492-Chloro-5-(2H-tetrazol-5-yl)-4-((thiophen-2-ylmethyl)amino)benzenesulfonamide
CAS :Degré de pureté :97.0%Couleur et forme :LiquidMasse moléculaire :370.8299865722656Ranitidine
CAS :<p>Applications Ranitidine (cas# 66357-35-5) was used as a standard for testing the therapeutic effect of brown propolis extract against aspirin and ethanol- induced gastric ulcers.<br>References Patil, M., et al.: Eur. J. Biomed. Pharma. Sci., 7, 620 (2020)<br></p>Formule :C13H22N4O3SCouleur et forme :NeatMasse moléculaire :314.401,2,3,4-Tetrahydro-4,6-dihydroxy-2-methyl-isoquinoline
CAS :<p>Impurity Phenylephrine 4,6-DMTQ Impurity (Peak-1)<br>Applications Product formed during the decomposition of Phenylephrine<br>References Millard, B., et al.: J. Pharm. Pharmacol., 25, 24 (1973),<br></p>Formule :C10H13NO2Couleur et forme :White To Light YellowMasse moléculaire :179.22Defluoro-6-chloro Norfloxacin Hydrochloride
CAS :Formule :C16H18ClN3O3·HClCouleur et forme :Off-WhiteMasse moléculaire :372.25METHYL 2-(2-BROMOTHIOPHEN-3-YL)ACETATE
CAS :Degré de pureté :90.0%Masse moléculaire :235.10000610351562Celecoxib
CAS :Produit contrôlé<p>Applications Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formule :C17H14F3N3O2SCouleur et forme :NeatMasse moléculaire :381.37Gabapentin-d4
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formule :C9D4H13NO2Couleur et forme :Off-WhiteMasse moléculaire :175.264-(4-Nitrophenyl)-3-morpholinone
CAS :Produit contrôléFormule :C10H10N2O4Couleur et forme :NeatMasse moléculaire :222.20Pyrimethamine
CAS :Produit contrôlé<p>Applications Dihydrofolate reductase inhibitor; generally used in combination with other antimicrobial agents. Antiprotozoal (Toxoplasma); antimalarial.<br>References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 463 (1983), Leport, C., et al.: Am. J. Med., 84, 94 (1988), McIntosh, H.M., et al.: Ann. Trop. Med., Parasitol., 93, 265 (1998), Plowe, C.V., et al.: Br. Med. J., 328, 545 (2004),<br></p>Formule :C12H13ClN4Couleur et forme :White To Off-WhiteMasse moléculaire :248.71Apatinib
CAS :Produit contrôlé<p>Applications Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mi, Y. et al.: Cancer Res., 70, 7981 (2010); Tong, X.Z. et al.: Biochem. Pharmacol., 83, 586 (2012); Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012);<br></p>Formule :C24H23N5O·CH4O3SCouleur et forme :NeatMasse moléculaire :493.5811-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
CAS :Produit contrôléFormule :C15H14N4O2Couleur et forme :NeatMasse moléculaire :282.3Iso Loratadine
CAS :Produit contrôlé<p>Impurity Loratadine EP Impurity E<br>Applications Iso Loratadine (Loratadine EP Impurity E) is a Loratadine (L469575) impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.<br>References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),<br></p>Formule :C22H23ClN2O2Couleur et forme :NeatMasse moléculaire :382.88N-Desmethyl Diphenhydramine Hydrochloride
CAS :<p>Applications N-Desmethyl Diphenhydramine is an impurity of Diphenhydramine (D486900) with antihistaminic activity.<br>References Nauta, W. T. et al.: Med. Chem., Spec. Contrib. Int. Symp., 3rd, 125 (1973);<br></p>Formule :C16H19NO·ClHCouleur et forme :White To Light BeigeMasse moléculaire :277.79N-[2-(3,4-Dihydro-1-oxo-2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide
CAS :Produit contrôlé<p>Impurity Praziquantel USP Related Compound C<br>Applications N-[2-(3,4-Dihydro-1-oxo-v2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide is a compound related to Praziquantel (P702095),effective against flatworms. Praziquantel USP Related Compound C.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formule :C19H22N2O4Couleur et forme :NeatMasse moléculaire :342.394-Chloro-1H -pyrazol-3-ylamine hydrochloride
CAS :Formule :C3H5Cl2N3Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :153.994’-O-Benzyloxy Ezetimibe
CAS :Produit contrôlé<p>Impurity Ezetimibe Benzyl Ether Impurity<br>Applications Protected Ezetimibe, used for the synthesis of related derivatives.<br>References Raman, B., et al.: J. Pharm. Biomed. Anal., 52, 73 (2010),<br></p>Formule :C31H27F2NO3Couleur et forme :NeatMasse moléculaire :499.55rac Mirabegron-d5
CAS :Produit contrôléFormule :C21H19D5N4O2SCouleur et forme :NeatMasse moléculaire :401.54Terbufoxon Sulfone
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications Terbufoxon Sulfone is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Formule :C9H21O5PS2Couleur et forme :NeatMasse moléculaire :304.36(2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications (2S)-1-(2-Chloroacetyl)-2-9-pyrrolidinecarbonitrile is a key intermediate for dipeptidyl peptidase IV inhibitor Vildagliptin (V305000).<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008);<br></p>Formule :C7H9ClN2OCouleur et forme :NeatMasse moléculaire :172.612-(4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)-5-(octyloxy)phenol
CAS :Degré de pureté :98%Masse moléculaire :509.69400024414061-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS :<p>Applications Used in the preparation of Mirtazapine (M365000) impurities.<br></p>Formule :C17H18N4Couleur et forme :Light Yellow To BrownMasse moléculaire :278.35Loxapine N-Oxide
CAS :<p>Stability Hygroscopic, Light Sensitive<br>Applications Loxapine N-Oxide is a metabolite of Loxapine (L472750), a D2/D4-Dopamine receptor antagonist. It is a serotonergic receptor antagonist that acts as a dibenzoxazepine antipsychotic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shen, Y., et al.: J. Biol. Chem., 268, 18200 (1993), Fiorella, D., et al.: Psychopharmacology, 121, 347 (1995), Glusa, E., et al.: Br. J. Pharmacol., 130, 692 (2000)<br></p>Formule :C18H18ClN3O2Couleur et forme :NeatMasse moléculaire :343.812-(3-Bromophenyl)-6-fluoroquinoline-4-carboxylic acid
CAS :Degré de pureté :98%Masse moléculaire :346.1549987792969Oxyphenbutazone
CAS :<p>Applications Anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 (2000), Chen, M., ET AL.: Pharm. Res., 18, 1645 (2001), Davis, A., et al.: Curr. Opin. Chem. Biol., 8, 378 (2004), Wang, J., ET AL.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Formule :C19H20N2O3Couleur et forme :NeatMasse moléculaire :324.37Levomepromazine EP Impurity D
Produit contrôléFormule :C32H33N3O2S2Couleur et forme :NeatMasse moléculaire :555.8N-Nitroso-Vildagliptin
CAS :Produit contrôléFormule :C17H24N4O3Couleur et forme :NeatMasse moléculaire :332.42-Amino-4-thiazoleacetic Acid
CAS :Produit contrôléFormule :C5H6N2O2SCouleur et forme :NeatMasse moléculaire :158.18α-(4-Chlorophenyl)-α-propionylacetonitrile
CAS :Produit contrôlé<p>Applications Pyrimethamine intermediate.<br>References Takayama, K., et al.: Antimicrob. Agents Chemother., 33, 1493 (1989), Robson, C., et al.: J. Med. Chem., 40, 3040 (1997), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Janin, Y., et al.: Bioorg. Med. Chem., 15, 2479 (2007),<br></p>Formule :C11H10ClNOCouleur et forme :White To BrownMasse moléculaire :207.66N-Formyl Apixaban
CAS :Produit contrôlé<p>Applications N-Formyl Apixaban is derived from Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formule :C26H25N5O5Couleur et forme :NeatMasse moléculaire :487.51N-Benzyl Hydroxymedetomidine
CAS :Produit contrôlé<p>Applications N-Benzyl Hydroxymedetomidine is an impurity of Medetomidine (M203250, HCl); an α2-adrenergic agonist, sedative, and analgesic.<br>References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996)<br></p>Formule :C20H22N2OCouleur et forme :NeatMasse moléculaire :306.44-AMINO-3-CHLOROPICOLINIC ACID METHYL ESTER
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :186.60000610351562N,N'-Methylene Ambroxol Hydrochloride
CAS :Produit contrôlé<p>Impurity Ambroxol EP Impurity B Hydrochloride<br>Stability Hygroscopic<br>Applications Ambroxol Cyclic Impurity is a metabolite as well as an impurity of the bronchosecretolytic drug, Ambroxol (A575900).<br>References Hammer, R. et al.: Arzneim.-Forsch., 28, 899 (1978); Nieder, M. et al.: HRC & CC, 9, 561 (1986); Huq, F. et al.: J. Pharmacol. Toxicol., 3, 147 (2008);<br></p>Formule :C14H18Br2N2O·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :426.57Elvitegravir
CAS :Produit contrôlé<p>Applications A novel inhibitor of human immunodeficiency virus type 1 integrase.<br>References Chou, T., et al.: Eur. J. Biochem., 115, 207 (1981), Baba, M., et al.: Antimicrob. Agents Chemother., 31, 1613 (1987), Craigie, R., et al.: J. Biol. Chem., 276, 23213 (2001), Chen, X., et al.: J. Mol. Biol., 380, 504 (2008),<br></p>Formule :C23H23ClFNO5Couleur et forme :NeatMasse moléculaire :447.88N-Nitroso Desmethyl Olopatadine
Produit contrôléFormule :C20H20N2O4Couleur et forme :NeatMasse moléculaire :352.3841-(2-naphthyl)-1H-pyrazole-4-carbaldehyde
CAS :Degré de pureté :95.0%Masse moléculaire :222.2469940185547Carboxymefloquine-d3
CAS :Produit contrôlé<p>Applications Labelled Carboxymefloquine (C178700). Carboxymefloquine is a metabolite of Mefloquine (M207050).<br>References Crevoisier, C., et al.: Eur. J. Clin. Pharmacol., 53, 135 (1997), Ridtitid, W., et al.: J. Pharm. Pharmacol., 52, 1265 (2000),<br></p>Formule :C12H2D3F6NO2Couleur et forme :NeatMasse moléculaire :312.182-(5-amino-3-methyl-1H-pyrazol-1-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :245.28599548339844N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine Formamide Hydrochloride
CAS :Produit contrôlé<p>Impurity Alfuzosin Hydrochloride EP Impurity E<br>Applications Alfuzosin (A532000) impurity. Alfuzosin (A532000) is an α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy. (Alfuzosin Hydrochloride EP Impurity E )<br>References Ramage, A.G., et al.: Eur. J. Pharmacol., 129, 307 (1986), Deering, A.H.,: Brit. J. Clin. Pharmacol., 25, 417 (1988), Priolo, L.D., et al.: Eur. J. Clin. Pharmacol., 35, 25 (1988),<br></p>Formule :C15H21N5O3·HClCouleur et forme :White To Off-WhiteMasse moléculaire :319.37 + (36.46)N-Methyl Pantoprazole(Mixture of 1 and 3 isomers)
CAS :<p>Impurity Pantoprazole EP Impurity D;<br>Applications N-Methyl Pantoprazole (Pantoprazole EP Impurity D) is an impurity of Omeprazole and Pantoprazole. Mixture of 1 and 3 isomers (mixture of impurity D and F).<br>References McClean, S., et al.: Anal. Chim. Acta, 292, 81 (1994), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997), Avgerinos, A., et al.: Eur. J. Drug Metab. Pharmacokinet., 23, 329 (1998), Wahbi, A., et al.: J. Pharm. Biomed. Anal., 30, 1133 (2002),<br></p>Formule :C17H17F2N3O4SCouleur et forme :Light RedMasse moléculaire :397.40Topiramate-13C6
CAS :Produit contrôlé<p>Applications Topiramate-13C6 is the labeled compound of Topiramate (T540250). Topiramate is used as an anticonvulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Formule :C6C6H21NO8SCouleur et forme :NeatMasse moléculaire :345.318Aripiprazole Dimer
CAS :Produit contrôlé<p>Impurity Aripiprazole EP Impurity G<br>Applications Aripiprazole Dimer is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Aripiprazole EP Impurity G<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998); Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998);<br></p>Formule :C48H56Cl4N6O4Couleur et forme :WhiteMasse moléculaire :922.81Nizatidine Sulfoxide
CAS :Produit contrôléFormule :C12H21N5O3S2Couleur et forme :NeatMasse moléculaire :347.462-Amino-5-ethylpyrazine
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :123.15899658203125
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