Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65576 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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N-Phenoxycarbonylparoxetine
CAS :Produit contrôlé<p>Applications N-Phenoxycarbonylparoxetine is an impurity of Paroxetine (P205750), a selective serotonin reuptake inhibitor. Used as an antidepressant.<br>References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),<br></p>Formule :C26H24FNO5Couleur et forme :NeatMasse moléculaire :449.47N-(2-(Phenylthio)phenyl)dibenzo[b,f][1,4]thiazepin-11-amine
CAS :Produit contrôléFormule :C25H18N2S2Couleur et forme :NeatMasse moléculaire :410.553',4'-Dihydroxyacetophenone
CAS :Produit contrôlé<p>Applications 3',4'-Dihydroxyacetophenone is an active constituent of Chinese medicine and also has antimelanogenic actiivity.<br>References Kim. Y., et al.: Biosci., Biotech., Biochem., 70, 532 (2006); Yang, D., et al.: Prostaglandins, 38, 497 (1989)<br></p>Formule :C8H8O3Couleur et forme :NeatMasse moléculaire :152.15Sertindole-d4
CAS :Produit contrôlé<p>Applications Antipsychotic used in the treatment of schizophrenia.<br>References Nourian, Z., et al.: Eur. J. Pharmacol., 596, 32 (2008), Karczewski, J., et al.: Biochem. Pharmacol., 77, 1602 (2009), Isoherranen, N., et al.: Chem. Res. Toxicol., 22, 294 (2009), Goetghebeur, P., et al.: Psychopharmacol., 202, 287 (2009),<br></p>Formule :C24H22D4ClFN4ODegré de pureté :~90%Couleur et forme :NeatMasse moléculaire :444.972-Amino-3-nitropyridine
CAS :Formule :C5H5N3O2Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :139.1144-Amino-2,6-dichloro-α-(4-chlorophenyl)benzeneacetonitrile
CAS :Produit contrôlé<p>Applications This compound is used in the synthesis of Diclazuril (D436200) and diclazuril derivatives.<br></p>Formule :C14H9Cl3N2Couleur et forme :NeatMasse moléculaire :311.591-Methoxy-Empagliflozin Tetraacetoxy
CAS :Formule :C32H37ClO12Couleur et forme :NeatMasse moléculaire :649.082Valsartan-d9 (Major)
CAS :Produit contrôlé<p>Applications An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formule :C24H20D9N5O3Couleur et forme :Off WhiteMasse moléculaire :444.57Celecoxib-d4
CAS :Produit contrôlé<p>Applications A labelled selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in the treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formule :C17H10D4F3N3O2SCouleur et forme :White To Light YellowMasse moléculaire :385.4Methyl 6-bromo-2-(4-methoxyphenyl)quinoline-4-carboxylate
CAS :Degré de pureté :95.0%Masse moléculaire :372.2179870605469DL-Norepinephrine Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Antagonist of dibutyryl cyclic-AMP in the regulation of narcosis.Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Piguet, P., et al.: J. Exp. Med., 173, 673 (1991), Hosoi, J., et al.: Nature, 363, 159 (1993), Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000), Kaplan, D., et al.: Immunity, 23, 611 (2005),<br></p>Formule :C8H11NO3·ClHCouleur et forme :NeatMasse moléculaire :205.642-(THIOPHEN-2-YL)-3H-QUINAZOLIN-4-ONE
CAS :Degré de pureté :95.0%Masse moléculaire :228.270004272460942-(BIPHENYL-4-YL)-4-CHLORO-6-PHENYL-1,3,5-TRIAZINE
CAS :Degré de pureté :98.0%Masse moléculaire :343.80999755859375Risperidone E-Oxime
CAS :Produit contrôléFormule :C23H28F2N4O2Couleur et forme :NeatMasse moléculaire :430.49Minoxidil Sulfate-d10
CAS :Produit contrôlé<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Formule :C9H5D10N5O4SCouleur et forme :NeatMasse moléculaire :299.37rac-5-Bromo Naproxen
CAS :Produit contrôléFormule :C14H13BrO3Couleur et forme :NeatMasse moléculaire :309.16Ethosuximide-d3
CAS :Produit contrôléFormule :C7H8D3NO2Couleur et forme :White To Light YellowMasse moléculaire :144.19XL184
CAS :Produit contrôléFormule :C28H24FN3O5Couleur et forme :White To Off-WhiteMasse moléculaire :501.51Bis(2-aminoethylthio)methane Dihydrochloride
CAS :Produit contrôlé<p>Applications Bis(2-aminoethylthio)methane is a potential inhibitor of γ-glutamylcysteine synthetase, the first enzyme in the glutathione biosynthesis pathway.<br>References Sweetman, B.J., et al.: J. Med. Chem., 12, 888 (1969); Seelig, G.F., et al.: J. Biol. Chem., 259, 3534 (1984);<br></p>Formule :C5H14N2S2·2(HCl)Couleur et forme :NeatMasse moléculaire :239.222-[[[4-(3-Methoxypropoxy)-3-methylpyridine-2-yl ]methyl]thio]-1H-benzimidazole
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :343.450012207031254-{[5-(Trifluoromethyl)pyridin-2-yl]oxy}benzaldehyde
CAS :Degré de pureté :97.0%Couleur et forme :SolidMasse moléculaire :267.2070007324219[1,1'-Biphenyl]-4-yl(phenyl)methanol
CAS :Produit contrôlé<p>Impurity Bifonazole EP Impurity A<br>Applications [1,1'-Biphenyl]-4-yl(phenyl)methanol (Bifonazole EP Impurity A) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formule :C19H16OCouleur et forme :NeatMasse moléculaire :260.33Agomelatine Dimer Urea
CAS :<p>Impurity Agomelatine Impurity 4<br>Applications Agomelatine Dimer Urea is an impurity of Agomelatine (A430020). Agomelatine Impurity 4<br>References Depreux, P., et al.: J. Med. Chem., 37, 3231 (1994); Wregget, K., et al.: J. Biol. Chem., 270, 22488 (1995); Ying, S., et al.: Eur. J. Pharmacol., 296, 33 (1996);<br></p>Formule :C27H28N2O3Couleur et forme :NeatMasse moléculaire :428.52Ribociclib nitroso impurity 1
Produit contrôléFormule :C23H29N9O2Couleur et forme :NeatMasse moléculaire :419.4952-(Aminomethyl)-1-ethylpyrrolidine
CAS :Produit contrôléFormule :C7H16N2Couleur et forme :Colourless To Light YellowMasse moléculaire :128.222-Nitrobenzaldehyde
CAS :<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Formule :C7H5NO3Couleur et forme :NeatMasse moléculaire :151.129-Piperazino Levofloxacin Impurity
CAS :Produit contrôlé<p>Applications A degradation product of Levofloxacin (L360000). Levofloxacin impurity.<br>References ierens, C., et al.: J. Pharm. Biomed. Anal., 22, 763 (2000), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003), Liang, Y., et al.: Anal. Chim. Acta, 510, 21 (2004),<br></p>Formule :C18H20FN3O4Couleur et forme :NeatMasse moléculaire :361.3685-Hydroxy Omeprazole-d3 Sodium Salt
CAS :Produit contrôléFormule :C17H15D3N3NaO4SCouleur et forme :White To Light YellowMasse moléculaire :386.42Thioridazine Hydrochloride
CAS :Produit contrôlé<p>Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Formule :C21H26N2S2·ClHCouleur et forme :Light YellowMasse moléculaire :407.04Gabapentin-d4
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formule :C9D4H13NO2Couleur et forme :Off-WhiteMasse moléculaire :175.26Celecoxib
CAS :Produit contrôlé<p>Applications Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Formule :C17H14F3N3O2SCouleur et forme :NeatMasse moléculaire :381.37Dolutegravir O-b-D-Glucuronide Sodium salt
Formule :C26H26F2N3NaO11Couleur et forme :White To Off-WhiteMasse moléculaire :617.49(S)-Naproxen
CAS :<p>Applications (S)-Naproxen is a a nonsteroidal anti-inflammatory compound with analgesic and antipyretic properties (1,2). (S)-Naproxen is also a potent COX1 inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)(2) Scott, W. W., et al.: World Neurosurg. 82, e633 (2014)<br></p>Formule :C14H14O3Couleur et forme :Off-WhiteMasse moléculaire :230.266-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
CAS :Produit contrôlé<p>Applications An Intermediate in the synthesis of risperidone and iloperidone.<br></p>Formule :C12H13FN2OCouleur et forme :NeatMasse moléculaire :220.245-Aminoimidazole-4-carboxamide
CAS :<p>Applications A metabolite of Temozolomide.<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999),<br></p>Formule :C4H6N4OCouleur et forme :White To Off-WhiteMasse moléculaire :126.124-(6-m-Tolyl-pyridin-3-yl)-pyrimidin-2-ylamine
Degré de pureté :95.0%Masse moléculaire :262.31600952148442,2'-Dithiobis[N-methyl-benzamide]
CAS :<p>Applications Benzamide, 2,2'-dithiobis[N-methyl- (cas# 2527-58-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C16H16N2O2S2Couleur et forme :Light Yellow To Light BeigeMasse moléculaire :332.444-Defluoro-2-fluoro Haloperidol
CAS :<p>Applications 4-Defluoro-2-fluoro Haloperidol is a positional isomer and impurity of the antipsychotic agent Haloperidol (H103700).<br></p>Formule :C21H23ClFNO2Couleur et forme :NeatMasse moléculaire :375.86N,O-Dibenzoyl-DL-tyrosyl-N’,N’-dipropylamide
CAS :Produit contrôlé<p>Applications N,O-Dibenzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B.<br>References Janssen, et al.: J. Pharm. Pharmacol., 9, 381 (1956), Bertaccini, et al.: Br. J. Pharmac., 34, 310 (1968),<br></p>Formule :C29H32N2O4Couleur et forme :White To Light RedMasse moléculaire :472.58Lenalidomide
CAS :Produit contrôlé<p>Applications Lenalidomide is an immunomodulatory drug; analog of Thalidomide.<br>References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),<br></p>Formule :C13H13N3O3Couleur et forme :WhiteMasse moléculaire :259.262-(2,5-dimethyl-1H-indol-3-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :320.8800048828125Gabapentin-d10
CAS :Produit contrôlé<p>Applications Gabapentin-d10 is the labelled analogue of Gabapentin (G117250), an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formule :C92H10H7NO2Couleur et forme :White To Off-WhiteMasse moléculaire :181.302-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate
CAS :<p>Applications 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.<br>References Francesco, C., et al.: Eur. J. Org. Chem., 27, 6011 (2015)<br></p>Formule :C11H13F3O5SCouleur et forme :NeatMasse moléculaire :314.278Levetiracetam-d3
CAS :Produit contrôléFormule :C8H11D3N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :173.232-Ethyl-2-methylsuccinic Acid
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 2-Ethyl-2-methylsuccinic Acid is an inhibitor of plasmid-borne IMP-1 metallo-β-lactamase.<br>References Toney, J., et. al.: J. Biol. Chem., 276, 31913 (2001)<br></p>Formule :C7H12O4Couleur et forme :NeatMasse moléculaire :160.168Dehydro Nimodipine
CAS :Produit contrôlé<p>Impurity Nimodipine EP Impurity A; Nimodipine USP Related Compound A<br>Stability Light Sensitive<br>Applications Dehydro Nimodipine (Nimodipine EP Impurity A; Nimodipine USP Related Compound A) is the dehydrogenated analogue and the major metabolite of the calcium channel blocker Nimodipine (N478200).<br>References Scherling, D. et al.: Arzneim.-Forsch., 41, 392 (1991); Liu, X. et al.: Yaox. Xueb., 35, 257 (2000); Eicher, H. et al.: Arch. Gerontol. Geriat., 14, 309 (1992);<br></p>Formule :C21H24N2O7Couleur et forme :Light YellowMasse moléculaire :416.42Rilpivirine-d6
CAS :Produit contrôlé<p>Applications A labelled novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.<br>References Sun, et al.: J. Med. Chem., 41, 4648 (1998); Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001);<br></p>Formule :C222H6H12N6Couleur et forme :White To YellowMasse moléculaire :372.46Stiripentol-d9
CAS :Produit contrôlé<p>Applications An labelled epilepsy drug. It has been used as co-therapy for treatment of epilepsy. It inhibits the enzymes responsible for metabolism of other anti-convulsant agents.<br>References Laurie, D., et al.: J. Neurosci., 12, 4151 (1992), Smith, A., et al.: J. Pharmacol. Exp. Therap., 311, 601 (2004), Trojnar, M., et al.: Pharm. Rep., 57, 154 (2005), Drafts, B., et al.: J. Pharm. Exp. Ther., 318, 1094 (2006), Picton, A., et al.: Brain Res., 1165, 40 (2007),<br></p>Formule :C14H9D9O3Couleur et forme :White SolidMasse moléculaire :243.35Sulindac-d6
CAS :Produit contrôlé<p>Applications Labelled analogue of Sulindac is a non-steroidal anti-inflammatory drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bjorkman. et al.: Am. J. Med., 105, 17S (1998); Thakur, et al.: Am. J. Hypertens., 12, 925 (1999);<br></p>Formule :C20H11D6FO3SCouleur et forme :NeatMasse moléculaire :362.45Macitentan
CAS :Produit contrôlé<p>Applications Macitentan, is an orally active endothelin receptor antagonist used for pulmonary arterial hypertension.<br>References Emoto, N. Ensho to Men'eki, 20, 487 (2012);<br></p>Formule :C19H20Br2N6O4SCouleur et forme :White To Off-WhiteMasse moléculaire :588.278-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide
CAS :Produit contrôlé<p>Impurity Aripiprazole Impurity 12<br>Applications 8-(2,3-Dichlorophenyl)-8-aza-5-azoniaspiro[4.5]decane Bromide is an intermediate used in the preparation of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Antipsychotic. Aripiprazole Impurity 12<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Formule :C14H19Cl2N2·BrCouleur et forme :NeatMasse moléculaire :366.122-((3-chlorophenyl)amino)quinazolin-4(3H)-one
CAS :Degré de pureté :95.0%Masse moléculaire :271.700012207031252-Amino-2-[2-(4-hexylphenyl)ethyl]-1,3-propanediol
CAS :Produit contrôléFormule :C17H29NO2Couleur et forme :NeatMasse moléculaire :279.422-Chloro-5-(2-phenyl-5-(pyridin-4-yl)-1H-imidazol-4-yl)phenol
CAS :Degré de pureté :95.0%Masse moléculaire :347.799987792968751,1-Cyclohexanediacetic Acid Monoamide
CAS :Produit contrôlé<p>Applications 1,1-Cyclohexanediacetic acid monoamide is an impurity of Gabapentin (G117250), an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Gabapentin is used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formule :C10H17NO3Couleur et forme :White To Off-WhiteMasse moléculaire :199.247Ethyl 5-(4-chlorophenoxy)-1-cyano-4-hydroxyisoquinoline-3-carboxylate
CAS :Degré de pureté :techMasse moléculaire :368.7699890136719Atazanavir-d6
CAS :Produit contrôlé<p>Applications Atazanavir-d6 is the isotope labelled analog of Atazanavir (A790051); an azapeptide HIV protease inhibitor. Atazanavir has also been investigated as potential treatment of human immunodeficiency virus (HIV) and for anticancer purposes.<br>References Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004); Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004)<br></p>Formule :C38H46D6N6O7Couleur et forme :NeatMasse moléculaire :710.89(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde
CAS :Degré de pureté :95%Masse moléculaire :317.3630065917969N-Ethoxycarbonyl Norfloxacin
CAS :Formule :C19H22FN3O5Couleur et forme :White To Off-WhiteMasse moléculaire :391.39Flutamide-d7
CAS :Produit contrôléFormule :C11D7H4F3N2O3Couleur et forme :NeatMasse moléculaire :283.255(Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS :Formule :C17H13NO4Couleur et forme :NeatMasse moléculaire :295.292-Hydroxymethyl Olanzapine-d3 (Major)
CAS :Produit contrôlé<p>Applications A minor labelled metabolite of Olanzapine.<br>References Moore, N., et al.: J. Pharmacol. Exper. Ther., 262, 545 (1992), Chiu, J., et al.: J. Pharmaceut. Biomed. Anal., 14, 609 (1996), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),<br></p>Formule :C17H17D3N4OSCouleur et forme :NeatMasse moléculaire :331.454,6-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :269.3699951171875N-(2,6-Dichlorophenyl)-carbonimidic Dichloride
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications N-(2,6-dichlorophenyl)-carbonimidic Dichloride is an impurity of clonidine (C587130). Chlonidine is α2-Adrenergic agonist. Antihypertensive; analgesic for neuropathic pain.<br>References Roach, A.G., et al.: J. Pharmacol. Exp. Ther., 227, 421 (1983), Glassman, A.H., et al.: Science, 226, 864 (1984), Abounassif, A.M., et al.: Anal. Profiles Drug Subs. Excip., 21, 109 (1992),<br></p>Formule :C7H3Cl4NCouleur et forme :NeatMasse moléculaire :242.925,6-Dihydro Tofacitinib
CAS :Produit contrôlé<p>Applications 5,6-Dihydro CP-690550 is an impurity of CP-690550 (C781350), a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.<br>References Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979); Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1993); Changelian, P., et al.: Science, 302, 875 (2003); Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (2003); Hutmacher, M., et al.: J. Clin. Pharmacol., 47, 238 (2007)<br></p>Formule :C16H22N6OCouleur et forme :NeatMasse moléculaire :314.39Desmethyl 2N-Nitroso Mirtazapine-d6 (major)
Produit contrôléFormule :C16D6H10N4OCouleur et forme :Neat4-(4-Hydroxyphenyl)-2-(4-phenyl-2-pyridyl)thiazole
CAS :Couleur et forme :Liquid, No data available.Masse moléculaire :330.4100036621094S-(2-Guanidino-4-thiazolyl)methylisothiourea Dihydrochloride
CAS :Formule :C6H10N6S2·2ClHCouleur et forme :NeatMasse moléculaire :303.2361-Pyridin-2-ylmethyl-piperidine-4-carboxylic acid
CAS :Formule :C12H16N2O2Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :220.2721-(2,4-Dimethylphenyl)-3,5-diphenyl-1H-pyrazole
CAS :Degré de pureté :95+%Masse moléculaire :324.427001953125Piribedil
CAS :Produit contrôlé<p>Applications Piribedil is an antiparkisonian agent that acts as a dopamine agonist. Piribedil also displays α2-adrenergic antagonist properties. Piribedil has also been shown to counteract age-related memory impairment by improving memory and attention as well as increasing the velocity of psychomotor reactions and lability of nervous processes.<br>References Millan, M.J. et al.: J. Pharmacol. Exp. Therap., 297, 876 (2001); Gobert, A. et al.: J. Pharmacol. Exp. Therap., 305, 338 (2003); Bochkarev, V.K. et al.: Zh. Nevrol. Psikhiatr. Im. S.S. Korsakova, 105, 46 (2005);<br></p>Formule :C16H18N4O2Couleur et forme :WhiteMasse moléculaire :298.34Ranitidine-d6 Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A histamine H2-receptor antagonist which inhibits gastric acid secretion. Antiulcerative.<br>References Bradshaw, J., et al.: Brit. J. Pharmacol., 66, 464 (1979), Berstad, A., et al.: Scand. J. Gastroenterol, 15, 637 (1980), Hohnjec, M., et al.: Anal. Profiles Drug Subs., 15, 533 (1986),<br></p>Formule :C132H6H16N4O3S·ClHDegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :356.90Chlorobenzene
CAS :Produit contrôlé<p>Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),<br></p>Formule :C6H5ClCouleur et forme :Clear ColourlessMasse moléculaire :112.56N-Nitroso Nebivolol-D₄
CAS :Produit contrôléFormule :C22D4H20F2N2O5Couleur et forme :Off-WhiteMasse moléculaire :438.4582-Morpholinoethane-1,1-diol hydrochloride
CAS :Degré de pureté :95+%Masse moléculaire :183.6300048828125Resiquimod-d5
CAS :Produit contrôlé<p>Applications Isotope labelled Resiquimod (R144680) is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formule :C17H17D5N4O2Couleur et forme :NeatMasse moléculaire :319.41Dehydro Felodipine
CAS :Produit contrôlé<p>Impurity Felodipine EP Impurity A<br>Applications Dehydro Felodipine (Felodipine EP Impurity A) is the primary metabolite of Felodipine.<br>References Bailey, D.G., et al.: Clin. Pharmacol. Ther., 60, 25 (1996), Lundahl, J., et al.: Eur. J. Clin. Pharmacol., 52, 139 (1997),<br></p>Formule :C18H17Cl2NO4Couleur et forme :NeatMasse moléculaire :382.244’-Hydroxymethyl 5’-Desmethyl Meloxicam
CAS :Produit contrôlé<p>Applications Meloxicam (M216100) derivative.<br></p>Formule :C14H13N3O5S2Couleur et forme :NeatMasse moléculaire :367.4Vortioxetine Hydrobromide-D8
CAS :Produit contrôlé<p>Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formule :C18D8H14N2S·BrHCouleur et forme :Off White PowderMasse moléculaire :387.4069N-Nitroso-metoprolol-D6
Produit contrôléFormule :C15H18D6N2O4Couleur et forme :NeatMasse moléculaire :302.39903Anastrozole Monoamide
CAS :<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formule :C17H21N5OCouleur et forme :WhiteMasse moléculaire :311.38N-Octyl Nortadalafil
CAS :Produit contrôlé<p>Applications Tadalafil (T004500) analog which is a phosphodiesterase 5 inhibitor.<br>References Jiru, M., et al.: J. Pharm. Biomed. Anal., 164, 713-724 (2019)<br></p>Formule :C29H33N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :487.59Etomidate-D5
CAS :Produit contrôlé<p>Applications A labelled isotope of Etomidate (E933300) which is used in neuroprotective products.<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Formule :C14D5H11N2O2Couleur et forme :NeatMasse moléculaire :249.328-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS :Produit contrôlé<p>Impurity Loratadine EP Impurity B; Loratadine USP Related Compound C<br>Applications 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (Loratadine EP Impurity B; Loratadine USP Related Compound C) is a Loratadine intermediate. Loratidine impurity C.<br>References Cox, A., et al.: Drugs, 61, 723 (2001), Caponigro, F., et al.: Anti-Cancer Drugs, 13, 891 (2002), , Haluska, P., et al.: Eur. J. Cancer, 38, 1685 (2002),<br></p>Formule :C14H10ClNOCouleur et forme :Light YellowMasse moléculaire :243.69Ofloxacin-d8
CAS :Produit contrôlé<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formule :C182H8H12FN3O4Couleur et forme :NeatMasse moléculaire :369.424'-[(1,7'-Dimethyl-2'-propyl[2,5'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic Acid
CAS :Produit contrôlé<p>Impurity Telmisartan EP Impurity B; Timolol USP Related Compound B<br>Applications 4’-Desmethyl-7’-methyl Telmisartan (Telmisartan EP Impurity B; Timolol USP Related Compound B) is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br></p>Formule :C33H30N4O2Couleur et forme :Off-WhiteMasse moléculaire :514.62Etomidate Acid
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Etomidate Acid is a metabolite and carboxylic acid analogue of the short-acting hypnotic drug, Etomidate (E933310).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heykants, J.J. et al.: Arch. Int. Pharnacodyn. Ther., 216, 113 (1975); Hammitzsch, M. et al.: Electrophoresis, 27, 4334 (2006);<br></p>Formule :C12H12N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :216.24Zileuton
CAS :Produit contrôlé<p>Applications An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic.<br>References Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991), Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1992), McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)<br></p>Formule :C11H12N2O2SCouleur et forme :NeatMasse moléculaire :236.29Atrazine-d5
CAS :Produit contrôlé<p>Applications Labelled selective herbicide. Potential symptoms of overexposure are irritation of eyes and skin<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dalgaard-Mikkelsen, S., et al.: Pharmacol. Rev., 14, 225 (1962), Muller, K., et al.: J. Environ. Qual., 31, 309<br></p>Formule :C82H5H9ClN5Couleur et forme :Off-WhiteMasse moléculaire :220.711-(9H-Carbazol-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
CAS :Produit contrôléFormule :C18H22N2O2Couleur et forme :Colourless Crystalline PowderMasse moléculaire :298.38Reduced Haloperidol-d4
CAS :Produit contrôlé<p>Applications Labelled Haloperidol Metabolite II<br>References Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006), Sheridan, R., et al.: J. Med. Chem., 50, 3173 (2007), Lee, I., et al.: Eur. J. Pharmacol., 578(2, 123 (2008), Entrena, J., et al.: Psychopharmacol., 205, 21 (2009),<br></p>Formule :C21H21D4ClFNO2Couleur et forme :White To Light YellowMasse moléculaire :381.9rac trans-Loxoprofen-d3 Alcohol
CAS :Produit contrôlé<p>Applications The cis-alcohol metabolite of Loxoprofen (L472900).<br>References Terada, A., et al.: J. Med. Chem., 27, 212 (1984), Sugimoto, M., et al.: Biochem. Pharmacol., 42, 2363 (1991), Riendeau, D., et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004)<br></p>Formule :C15H17D3O3Couleur et forme :NeatMasse moléculaire :251.34
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