Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65580 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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4-(2-(4-CHLORO-5H-PYRROLO[2,3-D]PYRIMIDIN-7(6H)-YL)ETHYL)MORPHOLINE
CAS :Degré de pureté :95.0%Masse moléculaire :268.755-Amino-1-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-3-methyl-1H-pyrazole-4-carbonitrile
Degré de pureté :95.0%Masse moléculaire :256.26501464843753,5-Dinitrosalicylhydrazide-15N2
CAS :Produit contrôlé<p>Applications Labelled Nifursol (N458700) metabolite.<br>References Shen, Y. et al.: Faming Zhuanli Shenqing 13 (2009)<br></p>Formule :C7H6N215N2O6Couleur et forme :Light YellowMasse moléculaire :244.137-chloro-8-methyl-2-phenylquinoline-4-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :297.739990234375Pefloxacin Mesylate Dihydrate
CAS :Produit contrôlé<p>Applications Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.<br></p>Formule :C17H20FN3O3·CH4O3S·2H2OCouleur et forme :Light YellowMasse moléculaire :465.495-Difluoromethoxy-2-[(3,4-dimethoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
CAS :Degré de pureté :95.0%Masse moléculaire :367.3699951171875N-Acetyldesloratadine
CAS :Produit contrôlé<p>Applications N-Acetyldesloratadine is an impurity in the synthesis of Desloratadine (D290250), Nonsedating-type histamine H1-receptor antagonist.<br>References Kreutner, W., et al.: Arzneimittel-Forsch., 50, 345 (2000); Salmun, L.M., et al.: Clin. Ther., 22, 613 (2000); Agrawal, D.K., et al.: Expert Opin. Invest. Drugs, 10, 547 (2001);<br></p>Formule :C21H21ClN2OCouleur et forme :NeatMasse moléculaire :352.867-Amino-5-chloro-2(3H)-benzoxazolone
CAS :Produit contrôléFormule :C7H5ClN2O2Couleur et forme :NeatMasse moléculaire :184.58Dehydronitrendipine
CAS :Produit contrôlé<p>Applications Dehydronitrendipine is a derivative of Nitrendipine (N490150), a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.<br>References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983); Kann, J. et al.: Brit. J. Clin. Pharmacol., 33, 51 (1992);<br></p>Formule :C18H18N2O6Couleur et forme :NeatMasse moléculaire :358.353-(3-Aminopropyl)-5-(1h-indol-3-yl)pyrazin-2-amine
CAS :Degré de pureté :98%Masse moléculaire :267.33599853515625Minoxidil Sulfate-d10
CAS :Produit contrôlé<p>Stability Light Sensitive - Protect from Light, Store in Freezer<br>Applications Labelled Minoxidil sulfate (M345100). Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14µM) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.<br>References Nakaya, Y., et al.: J. Dermatol. Sci., 7 (Suppl.), S104-S108 (1994), Ohtsuyama, M., et al.: J. Pharmacol. Exp. Ther., 269(2), 823 (1994), Andersson, K.E., et al.: Pharmacol. Toxicol., 70, 244 (1992), Bray, K.M., et al.: J. Biol. Chem., 267, 11689 (1992), Saitoh, M. et al.: Biochem. Biophys. Res. Commun., 140, 280 (1986)<br></p>Formule :C9H5D10N5O4SCouleur et forme :NeatMasse moléculaire :299.377-Hydroxy-4-(3-pyridyl)coumarin
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :239.22999572753906N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-QUINOXALINAMINE
CAS :Degré de pureté :95%Masse moléculaire :213.2440032958985-Methyl-2-phenyl-1,2-dihydropyrazol-3-one
CAS :Formule :C10H10N2ODegré de pureté :95%Couleur et forme :SolidMasse moléculaire :174.203Nateglinide Ethyl Ester
CAS :Produit contrôlé<p>Applications The ethyl ester of the oral hypoglycemic agent Nateglinide (N379375). It showed no effects on gross behavior in mice.<br>References Maeda, K. et al.: Yak. Chir., 25, S157 (1997);<br></p>Formule :C21H31NO3Couleur et forme :NeatMasse moléculaire :345.48N-(2-Succinyl) Phenylephrine(Mixture of Diastereomers) ( >85%)
CAS :<p>Impurity N-(2-Succinyl) Phenylephrine Impurity<br>Applications The major degradation product identified in Acetaminophen, Phenylephrine hydrochloride, and Chlorpheniramine maleate.<br>References Wong, J., et al.: Anal. Chem., 78, 7891 (2006),<br></p>Formule :C13H17NO6Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :283.286-(methylsulfonyl)-N-(pyridin-3-ylmethyl)benzo[d]thiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :319.3999938964844N-[4-Fluoro-3-(prop-2-enamido)phenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide
CAS :Degré de pureté :98.0%Masse moléculaire :368.3439941406253-Bromomethyl-thiophene-2-carboxylic acid methyl ester
CAS :Degré de pureté :97.0%Couleur et forme :Solid, Light yellow solidMasse moléculaire :235.10000610351562Nadolol-d9
CAS :Produit contrôlé<p>Applications Labelled Nadolol (N201052). β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977), Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978), Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980),<br></p>Formule :C17H18D9NO4Couleur et forme :NeatMasse moléculaire :318.462-(Aminomethyl)-1-ethylpyrrolidine
CAS :Produit contrôléFormule :C7H16N2Couleur et forme :Colourless To Light YellowMasse moléculaire :128.222-Nitrobenzaldehyde
CAS :<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Formule :C7H5NO3Couleur et forme :NeatMasse moléculaire :151.129-Piperazino Levofloxacin Impurity
CAS :Produit contrôlé<p>Applications A degradation product of Levofloxacin (L360000). Levofloxacin impurity.<br>References ierens, C., et al.: J. Pharm. Biomed. Anal., 22, 763 (2000), Kitade, T., et al.: Chem. Pharm. Bull., 51, 53 (2003), Liang, Y., et al.: Anal. Chim. Acta, 510, 21 (2004),<br></p>Formule :C18H20FN3O4Couleur et forme :NeatMasse moléculaire :361.3685-Hydroxy Omeprazole-d3 Sodium Salt
CAS :Produit contrôléFormule :C17H15D3N3NaO4SCouleur et forme :White To Light YellowMasse moléculaire :386.42Metomidate Hydrochloride
CAS :Produit contrôlé<p>Applications Metomidate Hydrochloride is used as an anesthetic for veterinary use.<br>References Harvey, B., et al.: Vet. Rec. 122(8), 174-7 (1988); Green, C. J., et al.: Lab. Anim., 15(2), 171-5 (1981); Cadle, D. R., et al.: Vet. Rec., 98(5), 91-2 1976); Massee, K. C., et al.: Aquaculture, 134(3-4), 351-359 (1995)<br></p>Formule :C13H14N2O2·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :266.722-o-Tolyl-pyridin-3-ylamine
CAS :Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :184.242004394531254-Anilino-4-oxobutanoic Acid
CAS :Produit contrôlé<p>Applications The metabolite (MII) of Suberoylanilide Hydroxamic Acid (S688700).<br>References Sun, W.S., et al.: J. Med. Chem., 46, 5619 (2003)<br></p>Formule :C10H11NO3Couleur et forme :NeatMasse moléculaire :193.20(S)-Bicalutamide
CAS :Produit contrôlé<p>Applications (S)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Formule :C18H14F4N2O4SCouleur et forme :WhiteMasse moléculaire :430.37Nizatidine
CAS :Produit contrôlé<p>Applications Histamine H2-receptor antagonist related to Ranitidine (R120000). Antiulcerative.<br>References Callaghan, J.T., et al.: Clin. Pharmacol. Ther., 37, 162 (1985), Secor, J.W., et al.: Br. J. Clin. Pharmacol., 20, 710 (1985), Knadler, M.P., et al.: Drug Metab. Dispos., 14, 175 (1986), Wozniak, T.J., et al.: Anal. Profiles Drug Subs., 19, 397(1990)<br></p>Formule :C12H21N5O2S2Couleur et forme :Off-White To Light YellowMasse moléculaire :331.462-[3,5-Dichloro-4-[(4-chlorophenyl)methyl]phenyl]-1,2,4-triazine-3,5(2H,4H)-dione
CAS :Produit contrôlé<p>Applications An anticoccidal triazine used for the treatment of coccidiosis in chickens. An impurity of Diclazuril (D436200).<br>References McFarland, J. et al.: J. Med. Chem., 35, 2543 (1992);<br></p>Formule :C16H10Cl3N3O2Couleur et forme :NeatMasse moléculaire :382.63Enzalutamide Carboxylic Acid
CAS :<p>Applications Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer.<br>References Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);<br></p>Formule :C20H13F4N3O3SCouleur et forme :NeatMasse moléculaire :451.39Maraviroc
CAS :Produit contrôléFormule :C29H41F2N5OCouleur et forme :White To Off-WhiteMasse moléculaire :513.673-(Methoxycarbonyl)thiophene-2-boronic acid
CAS :Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :185.990005493164064-(2-Methoxyethyl)phenol
CAS :Produit contrôlé<p>Impurity Metoprolol EP Impurity B<br>Applications 4-(2-Methoxyethyl)phenol (Metoprolol EP Impurity B) is an impurity of Metoprolol.<br>References McGourty, J., et al.: Br. J. Clin. Pharmacol., 20, 555 (1985), Zhou, H., et al.: Clin. Pharmacol. Ther., 47, 686 (1990), Koyama, E., et al.: J. Pharmacol. Exp. Ther., 271, 860 (1994)<br></p>Formule :C9H12O2Couleur et forme :NeatMasse moléculaire :152.19Nifursol-15N2,d2
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Nifursol (N458702). A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Formule :C12H5D2N315N2O9Couleur et forme :NeatMasse moléculaire :369.21Methyl 4’-[[2-n-Propyl-4-methyl-6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl]methyl]biphenyl-2-ca
CAS :Formule :C34H32N4O2Couleur et forme :YellowMasse moléculaire :528.64Thiophene-2-carboximidic acid ethyl ester; hydrochloride
CAS :Degré de pureté :95.0%Masse moléculaire :191.6699981689453Dihydroxy Moxonidine
CAS :Produit contrôlé<p>Impurity Moxonidine Impurity 1<br>Applications Dihydroxy Moxonidine (Moxonidine Impurity 1) is an impurity of Moxonidine (M745800).<br>References Diasio, R., et al.: Antimicrob. Agents Chemother., 14, 903 (1978), Yang, L., et al.: J. Pharm. Biomed. Anal., 22, 487 (2000),<br></p>Formule :C8H11N5O2Couleur et forme :NeatMasse moléculaire :209.212-amino-N-phenylquinoline-3-carboxamide
CAS :Degré de pureté :97%Masse moléculaire :263.29998779296875Nifursol (~90%)
CAS :Produit contrôlé<p>Applications A medicinal, prophylactic additive in animal feeds, protecting poultry from histomoniasis.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Kowalski, P., et al.: J. Pharm. Biomed. Anal., 32, 937 (2003), Khlebnikov, A., et al.: Bioorg. Med. Chem., 16, 9302 (2008), Schepetkin, I., et al.: Mol. Pharmacol., 74, 392 (2008),<br></p>Formule :C12H7N5O9Degré de pureté :~90%Couleur et forme :NeatMasse moléculaire :365.212-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications 2-Hydroxypropyl Nortadalafil is a derivative of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005), Toomey, V. et al.: J. Pharm. Biomed. Anal., 59, 50 (2012);<br></p>Formule :C24H23N3O5Couleur et forme :NeatMasse moléculaire :433.46Vildagliptin Amide
CAS :Produit contrôlé<p>Impurity Vildagliptin Amide Impurity<br>Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-prolinamide is an impurity of Vildagliptin (V305000) which is an oral anti-hyperglycemic agent that inhibit dipeptidyl peptidase 4 (DPP-4).<br>References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),<br></p>Formule :C17H27N3O3Couleur et forme :Off-WhiteMasse moléculaire :321.414’-Hydroxy Dutasteride
Produit contrôlé<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formule :C27H30F6N2O3Couleur et forme :NeatMasse moléculaire :544.53rac Normetanephrine-d3 Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A labelled metabolite of Epinephrine (E588585). A naturally occurring derivative of Epinephrine, found together with Metanephrine in urine and in certain tissues.<br>References Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82, 3864 (1997), Akiyama, T., et al.: Cardiovasc. Res., 49, 78 (2001), Burke, W., et al.: Brain Res., 891, 218 (2001),<br></p>Formule :C92H3H10NO3·ClHCouleur et forme :BeigeMasse moléculaire :222.68Nevirapine-d3
CAS :Produit contrôlé<p>Applications Labelled Nevirapine (N391275), a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.<br>References Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991), Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993), Guay, L.A., et al.: Lancet, 354, 795 (1999),<br></p>Formule :C15H11D3N4OCouleur et forme :White To Light BeigeMasse moléculaire :269.328-methyl-2-(2-methylphenyl)quinoline-4-carboxylic acid
CAS :Degré de pureté :95.0%Masse moléculaire :277.322998046875Maltol
CAS :<p>Applications A fragrance molecule used in flavor enhancers and fragrances.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Huang, Y., et al.: J. Food Sci., 75, C121 (2010), Tsuji, H., et al.: J. Food Sci., 75, C79 (2010),<br></p>Formule :C6H6O3Couleur et forme :NeatMasse moléculaire :126.11Pyrazinecarboxylic Acid-d3
CAS :Produit contrôlé<p>Applications Labelled analogue of Pyrazinecarboxylic Acid, a very potent urate retaining drug. Pyrazinecarboxylic Acid is a metabolite of the antibacterial agent Pyrazinamide (P840600).<br>References Fanelli, G.M. et al.: J. Clin. Invest., 52, 1946 (1973): Fanelli, G.M. et al.: J. Pharmacol. Exp. Therap., 200, 413 (1977); Lacroix, C. et al.: Arzneim.-Forsch., 40, 76 (1990); Kraemer, H.-J. et al.: J. Chrom. B Niomed. Sci. Appl., 706, 319 (1998);<br></p>Formule :C5HD3N2O2Couleur et forme :White To Light YellowMasse moléculaire :127.12Felbamate-d4
CAS :Produit contrôlé<p>Applications Antiepileptic, structurally similar to meprobamate.<br>References Swinyard, E.A., et al.: Epilepsia, 27, 27 (1986), Remmel, R.P., et al.: Ther. Drug Monit., 12, 90 (1990), Sofia, R.D., et al.: Epilepsy Res. Suppl., 3, 103 (1991),<br></p>Formule :C11H10D4N2O4Couleur et forme :NeatMasse moléculaire :242.267O-Desmethyl Mebeverine Acid
CAS :Produit contrôléFormule :C15H23NO3Couleur et forme :NeatMasse moléculaire :265.352-(4-n-Butoxybenzoyl)-5-(1,3-dioxolan-2-yl)thiophene
CAS :Degré de pureté :97.0%Masse moléculaire :332.4100036621094Irbesartan-d4
CAS :Produit contrôlé<p>Applications Irbesartan-d4 is the labeled analogue of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997); Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998); Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008); Ren, X., et al.: Pharmacol., 83, 80 (2009)Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals<br></p>Formule :C25H24D4N6OCouleur et forme :NeatMasse moléculaire :432.55Vortioxetine Hydrobromide-D8
CAS :Produit contrôlé<p>Applications Vortioxetine Hydrobromide-D8 is deuterium labeled Vortioxetine Hydrobromide (V766000), a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT (1,2,3).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Bang-Andersen, B., et al.: J. Med. Chem., 54, 3206 (2011)(2) Mørk, A., et al.: J. Pharmacol. Exp. Ther., 340, 666 (2012) (3) Mørk, A., et al.: Pharmacol. Biochem. Behav. 105C, 41 (2013)<br></p>Formule :C18D8H14N2S·BrHCouleur et forme :Off White PowderMasse moléculaire :387.40691-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide
CAS :Produit contrôlé<p>Impurity Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite<br>Applications 1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide (Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite) is a metabolite of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Alexandre, V., et. al.: J. Mol. Catal. B-Enzym., 29, 173 (2004); Rao, D.D., et. al.: J. Liq. Chromatogr. R. T., 35, 1973 (2012)<br></p>Formule :C25H30N6O2Couleur et forme :NeatMasse moléculaire :446.54Dehydro Nifedipine
CAS :Produit contrôlé<p>Impurity Nifedipine EP Impurity A<br>Applications The main Nifedipine metabolite in human plasma.This compound is a contaminant of emerging concern (CECs).<br>References Guengerich, F., et al.: J. Biol. Chem., 261, 5051 (1986), Bork, R., et al.: J. Biol. Chem., 264, 910 (1989), Kerla, V., et al.: Biochem. Pharmacol., 44, 1745 (1992),<br></p>Formule :C17H16N2O6Couleur et forme :Light YellowMasse moléculaire :344.32Trametinib
CAS :Produit contrôlé<p>Applications Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor and potent MEK inhibitor.<br>References Ercan, D. et al.: Canc. Disc., 2, 934 (2012); Mackiewicz-Wysocka, M. et al.: Exp. Opin. Investig. Drugs., 22, 181 (2013);<br></p>Formule :C26H23FIN5O4Couleur et forme :Off-WhiteMasse moléculaire :615.39Alogliptin-d3
CAS :Produit contrôlé<p>Applications Labelled Alogliptin (A575425). It is an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.<br>References Lynn, F., et al.: Diabetes, 50, 1004 (2001), Trumper, A., et al.: J. Endocrinol., 174, 233 (2002), Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009),<br></p>Formule :C182H3H18N5O2Couleur et forme :NeatMasse moléculaire :342.41Vismodegib
CAS :Produit contrôlé<p>Applications Vismodegib targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. Potent Hedgehog inhibitor.<br>References Gupta, S. et al.: Ther. Advances in Med. Oncology 2,237(2010)<br></p>Formule :C19H14Cl2N2O3SCouleur et forme :Off-WhiteMasse moléculaire :421.304-Bromo-1-chloro-6-methoxyisoquinoline
CAS :Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :272.5299988Clidinium Bromide
CAS :Produit contrôlé<p>Applications An anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formule :C22H26NO3·BrCouleur et forme :White SolidMasse moléculaire :432.352-Hydroxy Imipramine
CAS :Produit contrôlé<p>Applications A metabolite of Imipramine.<br>References De Jongh, G.D., et al.: Drug Metab. Dispos., 2, 48 (1981), Suckow, R.F., et al.: J. Pharm. Sci., 73, 1745 (1984), Fraser, A.D., et al.: J. Anal. Toxicol., 11,168 (1987),<br></p>Formule :C19H24N2OCouleur et forme :Yellowish SolidMasse moléculaire :296.41Nimodipine
CAS :<p>Applications A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Neuroprotective & Neuroresearch products.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Formule :C21H26N2O7Couleur et forme :NeatMasse moléculaire :418.447-CHLORO-2-(1-METHYL-1H-PYRAZOL-4-YL)-3H-IMIDAZO[4,5-B]PYRIDINE
CAS :Degré de pureté :95.0%Masse moléculaire :233.66000366210938N-Chloro Ethyl ThioTEPA
CAS :Produit contrôlé<p>Stability Hygroscopic, Moisture Sensitive<br>Applications N-Chloro Ethyl ThioTEPA is an impurity of ThioTEPA which is an alkylating agent used to treat cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maanen, M., et al.: Cancer Treatment Rev., 26, 257 (2000); Sykes, M., et al.: Cancer, 6, 142 (1953)<br></p>Formule :C6H13ClN3PSCouleur et forme :White To Off-WhiteMasse moléculaire :225.68S-Methyldihydroziprasidone
CAS :Produit contrôlé<p>Applications S-Methyldihydroziprasidone is a metabolite of Ziprasidone (Z485000) and is used for the treatment of psychiatric and ocular disorders.<br>References Obach, R.S., et al.: Xenobiotica, 42, 1049 (2012); Prakash, C., et al.: Drug Metab. Dispos., 25, 863 (1997); Prakash, C., et al. S-Methyl-dihydro-ziprasidone for treatment of psychiatric and ocular disorders. PCT Int. Appl. WO 2001091756 A2 20011206. Dec 6, 2001<br></p>Formule :C22H25ClN4OSCouleur et forme :NeatMasse moléculaire :428.98DL-erythro Ritalinic Acid-d10 (Major)
CAS :Produit contrôléFormule :C13H7D10NO2Couleur et forme :NeatMasse moléculaire :229.344'-(4-(1H-Tetrazol-5-yl)phenyl)-2,2':6',2''-terpyridine
CAS :Degré de pureté :98%Masse moléculaire :377.4110107421875trans-Haloperidol N-Oxide
CAS :Produit contrôlé<p>Applications trans-Haloperidol N-Oxide is the trans-isomer of Haloperidol N-Oxide (H103735), a metabolite of Haloperidol (H103700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorrod, J., et al.: Xenobiotica., 23, 495 (1993); Monser, L., et al.: J. Liquid. Chromatograph. Technol., 26, 261 (2003);<br></p>Formule :C21H23ClFNO3Couleur et forme :NeatMasse moléculaire :391.864-(2-Oxo-1,2,3,4-tetrahydroquinolin-6-yl)oxy Cilostazol (>85%)
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications An impurity of Cilostazol (C441500) which is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Formule :C29H34N6O4Degré de pureté :>85%Couleur et forme :NeatMasse moléculaire :530.62Anastrozole Monoamide
CAS :<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Formule :C17H21N5OCouleur et forme :WhiteMasse moléculaire :311.38N-Octyl Nortadalafil
CAS :Produit contrôlé<p>Applications Tadalafil (T004500) analog which is a phosphodiesterase 5 inhibitor.<br>References Jiru, M., et al.: J. Pharm. Biomed. Anal., 164, 713-724 (2019)<br></p>Formule :C29H33N3O4Couleur et forme :White To Off-WhiteMasse moléculaire :487.59ent Atomoxetine-d3, Hydrochloride
CAS :Produit contrôléFormule :C17H19D3ClNOCouleur et forme :NeatMasse moléculaire :294.832-Pyrrolidin-1-ylquinolin-8-ol
CAS :Degré de pureté :95.0%Couleur et forme :SolidMasse moléculaire :214.268005371093753-Chloro-4-morpholino-1,2,5-thiadiazole
CAS :Produit contrôlé<p>Impurity Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F<br>Applications 3-Chloro-4-morpholino-1,2,5-thiadiazole (Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F) is an intermediate for the synthesis of Timolol.<br>References Wasson, B., et al.: J. Med. Chem., 15, 651 (1972), Tokunaga, M., et al.: Sci., 277, 936 (1997),<br></p>Formule :C6H8ClN3OSCouleur et forme :White To Off-WhiteMasse moléculaire :205.672-(5-Methyl-furan-2-yl)-4-(3-nitro-phenyl)-6-phenyl-pyridine
CAS :Masse moléculaire :356.3810119628906Etomidate-D5
CAS :Produit contrôlé<p>Applications A labelled isotope of Etomidate (E933300) which is used in neuroprotective products.<br>References Goetz, E., et al.: Anaesthesist, 23, 331 (1974), Chang, Z. L., et al.: Anal. Profiles Drug Subs., 12, 191 (1983),<br></p>Formule :C14D5H11N2O2Couleur et forme :NeatMasse moléculaire :249.328-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS :Produit contrôlé<p>Impurity Loratadine EP Impurity B; Loratadine USP Related Compound C<br>Applications 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one (Loratadine EP Impurity B; Loratadine USP Related Compound C) is a Loratadine intermediate. Loratidine impurity C.<br>References Cox, A., et al.: Drugs, 61, 723 (2001), Caponigro, F., et al.: Anti-Cancer Drugs, 13, 891 (2002), , Haluska, P., et al.: Eur. J. Cancer, 38, 1685 (2002),<br></p>Formule :C14H10ClNOCouleur et forme :Light YellowMasse moléculaire :243.696-Bromo-7-methoxy-2-methylquinazolin-4(3H)-one
CAS :Degré de pureté :97.0%Masse moléculaire :269.0979919433594Hydroxy Brimonidine Trifluoroacetic Acid Salt
CAS :<p>Impurity Brimonidine EP Impurity G<br>Applications A possible metabolite of Brimonidine (B677520).<br></p>Formule :C11H12BrN5O·C2HF3O2Couleur et forme :NeatMasse moléculaire :424.1732Argatroban
CAS :<p>Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.</p>Formule :C23H36N6O5SDegré de pureté :99.77% - >99.99%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :508.63Ofloxacin-d8
CAS :Produit contrôlé<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987), Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Formule :C182H8H12FN3O4Couleur et forme :NeatMasse moléculaire :369.424-ethoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS :Degré de pureté :95.0%Masse moléculaire :285.36999511718752,4-Bis(benzyloxy)-6-chloro-1,3,5-triazine
CAS :Degré de pureté :95% HPLC,TMasse moléculaire :327.7699890136719Bis(aminoethoxy) Amlodipine
CAS :<p>Impurity Amlodipine EP Impurity C<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity C<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Formule :C22H30ClN3O6Couleur et forme :NeatMasse moléculaire :467.941,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride
CAS :Produit contrôlé<p>Impurity Bifonazole EP Impurity D<br>Applications 1,3-Bis([1,1’-Biphenyl]-4-ylphenylmethyl)-1H-imidazolium Chloride (Bifonazole EP Impurity D) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Formule :C41H33N2·ClCouleur et forme :NeatMasse moléculaire :589.17Sodium (S)-6-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide
CAS :Degré de pureté :97%Masse moléculaire :405.3500061035156Nifedipine Monoamide
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Nifedipine Monoamide is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.<br>References Zhu, P., et al.: Sepu, 30, 1026 (2012); Karancsi, T., et al.: Acta Pharm. Hung., 66, 21 (1996); Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989); Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991); Brown, M.J., et al.: Lancet, 356, 366 (2000)<br></p>Formule :C16H17N3O5Couleur et forme :Orange SolidMasse moléculaire :331.32
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