Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65630 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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Stepronin
CAS :<p>Stepronin (TTPG) shows expectorant activities and inhibits airway secretion.</p>Formule :C10H11NO4S2Degré de pureté :99.59%Couleur et forme :White Or Off White CrystallineMasse moléculaire :273.33UNC0321
CAS :<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formule :C27H45N7O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :515.69Desfluoro ezetimibe
CAS :<p>Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.</p>Formule :C24H22FNO3Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :391.43 g/molAGPS-IN-2i
CAS :AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Formule :C18H17F2N3O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :345.34(R)-Zanubrutinib
CAS :<p>(R)-Zanubrutinib ((R)-BGB-3111) is a selective inhibitor of Bruton tyrosine kinase (BTK).</p>Formule :C27H29N5O3Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :471.55MMP2-IN-3
CAS :<p>MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).</p>Formule :C23H21N3ODegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :355.433-Trifluoroacetylamino linagliptin
CAS :<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C27H27F3N8O3Degré de pureté :Min. 95%Masse moléculaire :568.55 g/molPramipexole EP Impurity C
CAS :<p>Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>Formule :C20H32N6S2Degré de pureté :Min. 95%Ephedrine Hydrochloride
CAS :Produit contrôléEphedrine and its saltsFormule :C10H15NO·HClCouleur et forme :White Off-White PowderMasse moléculaire :201.09204PG-116800
CAS :<p>PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.</p>Formule :C24H27N3O7SDegré de pureté :98.03% - 99.66%Couleur et forme :SolidMasse moléculaire :501.55Vildagliptin Related Compound 2
CAS :<p>Vildagliptin Related Compound 2 is a synthetic compound that has been shown to be an inhibitor of DPP-4. It is a white solid that can be synthesized by condensation of vildagliptin with chloroacetyl chloride in the presence of an alkali. The compound was found to have impurities, including 1-(2-chlorophenyl)ethanol and 3-chlorobenzaldehyde.</p>Formule :C17H25N3O2Degré de pureté :Min. 95%Masse moléculaire :303.4 g/mol(S)-Rabeprazole sodium
CAS :<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formule :C18H21N3O3S•NaDegré de pureté :Min. 95%Masse moléculaire :382.43 g/mol2,3,4,5-Tetradehydro alfuzosin hydrochloride
CAS :<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>Formule :C19H24ClN5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :421.88 g/molPitavastatin N-oxide
CAS :<p>Pitavastatin N-oxide is a drug product that is an analytical standard and natural API impurity. It is used in the synthesis of other drugs, such as pitavastatin, which is a statin drug used to lower cholesterol levels. Pitavastatin N-oxide has been shown to be a potent inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonate. This inhibits cholesterol production and lowers levels of low density lipoprotein (LDL) cholesterol in the blood.</p>Formule :C25H24FNO5Degré de pureté :Min. 95%Masse moléculaire :437.46 g/molSovaprevir
CAS :<p>Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.</p>Formule :C43H53N5O8SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :799.97Cyamemazine
CAS :Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Formule :C19H21N3SDegré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :323.46Amiodarone impurity E
CAS :<p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>Formule :C19H18O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :294.34 g/molVildagliptin carboxylic acid methyl ester
CAS :<p>Please enquire for more information about Vildagliptin carboxylic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C18H28N2O4Degré de pureté :Min. 95%Masse moléculaire :336.43 g/mol(Z)-Thiothixene
CAS :<p>(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.</p>Formule :C23H29N3O2S2Degré de pureté :99.21%Couleur et forme :Yellow To Yellow With A Tan Cast PowderMasse moléculaire :443.631-Fluoronaphthalene
CAS :<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>Formule :C10H7FDegré de pureté :Min. 95%Masse moléculaire :146.16 g/molViloxazine
CAS :<p>Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity</p>Formule :C13H19NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :237.29Amlodipine EP Impurity E maleate
CAS :<p>Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br>br></p>Formule :C21H27ClN2O5•C4H4O4Degré de pureté :Min. 95%Masse moléculaire :538.98 g/molImipramine
CAS :<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formule :C19H24N2Degré de pureté :99.4%Couleur et forme :White To Off-White /Hydrochloride/ SolidMasse moléculaire :280.41(R,R)-Montelukast bis-sulfide
CAS :<p>(R,R)-Montelukast bis-sulfide is a drug product that is used in the analytical and research and development of drugs. It is also used as an impurity standard for HPLC. (R,R)-Montelukast bis-sulfide has been shown to have niche applications in drug development and research, as well as being a high purity API.</p>Formule :C41H46ClNO5S2Degré de pureté :90%MinMasse moléculaire :732.39 g/molGallopamil
CAS :Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.Formule :C28H40N2O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :484.63Gemigliptin
CAS :<p>Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)</p>Formule :C18H19F8N5O2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :489.36ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
CAS :<p>Please enquire for more information about ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C22H22N4O4Degré de pureté :Min. 95%Masse moléculaire :406.43 g/molMoveltipril
CAS :<p>Moveltipril (Moveltipril calcium) is a potent angiotensin-converting enzyme (ACE) inhibitor.Moveltipril is converted to captopril in the body for action.</p>Formule :C19H30N2O5SDegré de pureté :97.55% - 98.28%Couleur et forme :SolidMasse moléculaire :398.52N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS :<p>N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.</p>Formule :C12H9F3N2O2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :270.21 g/molPitolisant
CAS :Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.Formule :C17H26ClNODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :295.85Vildagliptin related compound F
CAS :<p>Vildagliptin related compound F (VRCF) is a drug product that has been custom synthesized. VRCF is a high purity, analytical standard. It is metabolized in the body and can be used as a research and development standard to study the metabolism of vildagliptin. VRCF is a natural metabolite that has been identified as an impurity in the drug product Vildagliptin. VRCF has not been recognized by the USP or EP for use as an impurity standard. CAS no: 1789703-36-1</p>Formule :C17H24N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :304.4 g/molEdoxaban
CAS :<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formule :C24H30ClN7O4SDegré de pureté :97.67% - 99.71%Couleur et forme :SolidMasse moléculaire :548.06Laduviglusib trihydrochloride
CAS :<p>Laduviglusib trihydrochloride, a GSK-3α/β inhibitor (IC50: 10/6.7 nM), activates Wnt/β-catenin signaling and induces autophagy.</p>Formule :C22H20Cl5N8Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :573.71Pantoprazole sulphide
CAS :<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formule :C16H15F2N3O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :367.37 g/molEzetimibe ketone
CAS :<p>Ezetimibe ketone is a lipid-lowering agent that inhibits cholesterol absorption through the inhibition of Niemann-Pick C1-like 1 (NPC1L1). Ezetimibe ketone is used to reduce the levels of low-density lipoprotein cholesterol (LDL-C) in patients with primary hypercholesterolemia, sitosterolemia, and familial combined hyperlipidemia. Ezetimibe ketone has been shown to be bioequivalent to ezetimibe, which is an oral drug that inhibits cholesterol absorption by blocking NPC1L1. The drug binds to the NPC1L1 receptor in the brush border membrane of enterocytes and prevents cholesterol uptake. Ezetimibe ketone has a high solubility in organic solvents such as dichloromethane or chloroform. It also has a high melting point, which makes it suitable for use on chromatographic columns.</p>Formule :C24H19F2NO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :407.41 g/molBrivaracetam CV
CAS :Produit contrôléLactams, nesoiFormule :C11H20N2O2Couleur et forme :White Off-White SolidMasse moléculaire :212.15248MMP-9 Inhibitor I
CAS :<p>MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).</p>Formule :C27H33N3O5SCouleur et forme :SolidMasse moléculaire :511.63RU 58668
CAS :<p>Pure antiestrogen that downregulates estrogen receptor expression</p>Formule :C34H43F5O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :658.76IK-862
CAS :<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Formule :C25H27N3O4Degré de pureté :97.75% - 98.29%Couleur et forme :SolidMasse moléculaire :433.5MMP3 inhibitor 1
CAS :MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).Formule :C23H31N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.57FGIN-1-27
CAS :<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.6Thioquinapiperifil
CAS :<p>Thioquinapiperifil is a type of phosphodiesterase-5 (PDE-5) inhibitor found in dietary supplements.</p>Formule :C24H28N6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :448.58Celiprolol hydrochloride
CAS :Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity.Formule :C20H33N3O4·HClCouleur et forme :White Crystalline SolidMasse moléculaire :415.96Etidocaine Hydrochloride
CAS :<p>Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel.</p>Formule :C17H29ClN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.88Quizalofop
CAS :Quizalofop (Xylafop) is a reagent of biochemical.Formule :C17H13ClN2O4Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :344.75MMP-3 Inhibitor VIII
CAS :<p>Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.</p>Formule :C20H26N2O5SCouleur et forme :SolidMasse moléculaire :406.5LY52
CAS :LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.Formule :C22H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.45Brasofensine
CAS :<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formule :C16H20Cl2N2OCouleur et forme :SolidMasse moléculaire :327.25Caroverine
CAS :Caroverine is a potential chemotherapeutical agent in HNSCC cell lines.Formule :C22H27N3O2Couleur et forme :SolidMasse moléculaire :365.47Ro 31-9790
CAS :<p>Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).</p>Formule :C15H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.41Apratastat
CAS :Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs)Formule :C17H22N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.5Carmoxirole hydrochloride
CAS :<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Formule :C24H27ClN2O2Degré de pureté :99.37% - 99.62%Couleur et forme :SolidMasse moléculaire :410.94Ritodrine
CAS :<p>Ritodrine (DU21220) is a β-adrenergic agonist as well as an effective uterine relaxant that can be used in arrest premature labor research[1] [2].</p>Formule :C17H21NO3Couleur et forme :SolidMasse moléculaire :287.35ICI 204448
CAS :<p>ICI 204448 is a potent and peripherally selective κ-opioid agonist.</p>Formule :C23H26Cl2N2O4Couleur et forme :SolidMasse moléculaire :465.37MMP-7-IN-3
CAS :<p>MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.</p>Formule :C34H43ClF3N7O9SDegré de pureté :99.915%Couleur et forme :SolidMasse moléculaire :818.26TP0556351
CAS :<p>TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.</p>Formule :C50H70N10O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1067.15PIM447
CAS :<p>PIM447 (LGH447) is a pan-PIM kinase inhibitor with anti-tumor and bone protective effects. PIM447 reduces the viability, and motility of HuH6 cell.</p>Formule :C24H23F3N4ODegré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :440.46MMP-145
CAS :<p>MMP-145 is used as a protease inhibitor.</p>Formule :C20H20N2O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.45Fluvalinate
CAS :<p>Fluvalinate is a synthetic chemical compound and can be commonly used to control varroa mites in honey bee colonies.</p>Formule :C26H22ClF3N2O3Couleur et forme :SolidMasse moléculaire :502.91Naxagolide free base
CAS :Naxagolide is a sustained release formulation. It is a dopamine agonist.Formule :C15H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.33XL-784
CAS :XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.Formule :C42H42Cl2F4MgN6O16S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1122.15Bufuralol
CAS :<p>Bufuralol (Ro 3-4787) is a 尾-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.</p>Formule :C16H23NO2Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :261.36ROCK2-IN-7
CAS :<p>ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis.</p>Formule :C26H28FN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.53(Rac)-Lonafarnib
CAS :<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Formule :C27H31Br2ClN4O2Couleur et forme :SolidMasse moléculaire :638.82XL-784 free base
CAS :<p>XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).</p>Formule :C21H22ClF2N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.93Frovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.3Tianagliflozin
CAS :<p>Tianagliflozin, a sodium/glucose cotransporter 2 (SGLT-2) inhibitor, is used potentially for the treatment of type 2 diabetes.</p>Formule :C21H25ClO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.87Z-PDLDA-NHOH
CAS :<p>Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].</p>Formule :C22H32N4O6Couleur et forme :SolidMasse moléculaire :448.51Ubrogepant
CAS :Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formule :C29H26F3N5O3Degré de pureté :99.452% - 99.78%Couleur et forme :SolidMasse moléculaire :549.54Bufuralol (hydrochloride)
CAS :<p>Bufuralol hydrochloride is a potent, non-selective, orally active β-blocker with partial agonist effects and a CYP2D6 probe.</p>Formule :C16H24ClNO2Couleur et forme :SolidMasse moléculaire :297.82MMP-7-IN-2
CAS :<p>MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.</p>Formule :C28H40ClF3N6O9SDegré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :729.17Collagen proline hydroxylase inhibitor
CAS :<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formule :C18H18N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.36Levocabastine
CAS :<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formule :C26H29FN2O2Couleur et forme :SolidMasse moléculaire :420.52Brilaroxazine
CAS :<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formule :C22H25Cl2N3O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :450.36Yonkenafil
CAS :<p>Yonkenafil, a PDE5 inhibitor, may reduce stroke damage and aid in Alzheimer's treatment.</p>Formule :C24H33N5O4SCouleur et forme :SolidMasse moléculaire :487.61Saredutant
CAS :<p>Saredutant (SR 48968) is a selective neurokinin-2 (NK2) receptor antagonist that inhibits neurokinin A by blocking NK2 receptor, antidepressant and anxiolytic.</p>Formule :C31H35Cl2N3O2Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :552.54Gepirone
CAS :<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formule :C19H29N5O2Degré de pureté :99.35% - 99.89%Couleur et forme :SolidMasse moléculaire :359.47ONO 4817
CAS :ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.Formule :C22H28N2O6Couleur et forme :SolidMasse moléculaire :416.47Dibenamine hydrochloride
CAS :<p>Dibenamine hydrochloride is a competitive and irreversible blocking agent of the β-adrenergic receptor.</p>Formule :C16H19Cl2NDegré de pureté :96.43%Couleur et forme :Oily Liquid SolidMasse moléculaire :296.23AZD-1656
CAS :AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2Formule :C24H26N6O5Degré de pureté :97.07% - 99.37%Couleur et forme :SolidMasse moléculaire :478.5Ro 32-7315
CAS :<p>Ro 32-7315 is a selective inhibitor of ADAM17.</p>Formule :C22H35N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.6Cobimetinib racemate
CAS :<p>Cobimetinib racemate (Cobimetinib (racemate)) (GDC-0973 racemate) is a selective inhibitor of MEK.Cobimetinib racemate is also known as a mitogen-activated</p>Formule :C21H21F3IN3O2Degré de pureté :98.00% - 99.71%Couleur et forme :SolidMasse moléculaire :531.31Gisadenafil
CAS :<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Formule :C23H33N7O5SDegré de pureté :98.82% - 99.50%Couleur et forme :SolidMasse moléculaire :519.62Inz-1
CAS :Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Formule :C16H14N2O2Degré de pureté :99.55% - 99.88%Couleur et forme :SolidMasse moléculaire :266.29Cipemastat
CAS :<p>Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).</p>Formule :C22H36N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.55Zandelisib
CAS :<p>Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.</p>Formule :C31H38F2N8ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :576.68MMP13-IN-3
CAS :MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.Formule :C24H22N4O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :446.46Pirtobrutinib
CAS :<p>Pirtobrutinib: a selective, non-covalent BTK inhibitor effective against BTK C481 mutations, causing tumor regression in lymphoma models.</p>Formule :C22H21F4N5O3Degré de pureté :99.76% - 99.94%Couleur et forme :SolidMasse moléculaire :479.43ND-378
CAS :<p>ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.</p>Formule :C18H19NO4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48Mefenidil
CAS :Mefenidil (McN-2378), a selective cerebral vasodilator, was shown to increase CBF in healthy brains without stimulating O2 uptake in a dog anesthesia model.Formule :C12H11N3Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :197.24KB-R7785
CAS :<p>KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.</p>Formule :C18H27N3O4Couleur et forme :SolidMasse moléculaire :349.42Dothiepin
CAS :<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formule :C19H21NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.44LX7101
CAS :LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).Formule :C23H29N7O3Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :451.52Maralixibat Chloride
CAS :<p>Maralixibat Chloride (LUM001 chloride), an apical, sodium-dependent, bile acid transport inhibitor, prevents enterohepatic bile acid recirculation.</p>Formule :C40H56ClN3O4SDegré de pureté :99.19% - 99.65%Couleur et forme :SolidMasse moléculaire :710.414-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride
CAS :<p>4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride is a drug product. It is used as an analytical standard and in the development of drugs. The metabolite of 4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-benzaldehyde hydrochloride, 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N-(4-nitrophenyl)benzamide, has been shown to inhibit the production of cytokines IL6 and TNFα by human monocytes, macrophages, and dendritic cells. Metabolism studies have shown that 4-[(2RS)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-N</p>Formule :C13H20ClNO3Degré de pureté :Min. 95%Masse moléculaire :273.76 g/mol1-(6-Chloro-9H-carbazol-2-yl)ethanone
CAS :<p>1-(6-Chloro-9H-carbazol-2-yl)ethanone is a chemical substance that belongs to the class of synthetic drugs. It is used as a pharmaceutical intermediate in the production of other chemical substances, including antibiotics and antihypertensives. 1-(6-Chloro-9H-carbazol-2-yl)ethanone has been shown to be metabolized by cytochrome P450 enzymes and by glucuronidases or esterases. This product can also be used as an impurity standard for HPLC analyses of fluoroquinolones.</p>Formule :C14H10ClNODegré de pureté :Min. 95%Masse moléculaire :243.69 g/mol7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole
CAS :<p>7'-Methyl-2'-propyl-2,5'-bi-1H-benzimidazole (7'-MPB) is a benzimidazole derivative that is used as a medicine. It is made from recycled chemicals and has shown to have industrial applications as a catalyst for cyclization reactions. 7'-MPB is also used in the production of benzenesulfonic acid, which is an organic solvent. This chemical has been shown to be effective against high blood pressure, but has not been tested on humans yet. Telmisartan, which belongs to the angiotensin II receptor blocker class of drugs, can inhibit the synthesis of prostaglandins.</p>Formule :C18H18N4Degré de pureté :Min. 95%Masse moléculaire :290.36 g/molAderamastat
CAS :<p>Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.</p>Formule :C21H18N2O4SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :394.44Collagen proline hydroxylase inhibitor-1
CAS :<p>Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。</p>Formule :C24H21N5O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :443.45Sitagliptin impurity E
CAS :<p>Sitagliptin impurity E is an inhibitor of dipeptidyl peptidase-4 (DPP-IV) that is used as a hypoglycemic agent. Sitagliptin impurity E has been shown to increase the glucose-lowering effect in diabetic patients with type 2 diabetes mellitus. It is also effective in reducing postprandial glucose and insulin levels. Sitagliptin impurity E has been shown to increase the concentration of insulin in plasma for up to 24 hours after administration, which suggests that it may be useful for the treatment of metabolic disorders such as obesity and type 2 diabetes mellitus.</p>Formule :C16H15F6N5ODegré de pureté :Min. 95%Masse moléculaire :407.31 g/mol
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