Dérivés de Quinazoline et de Quinoléine
Les quinazolines et les quinoléines sont des composés hétérocycliques azotés à structure aromatique qui jouent un rôle clé dans la synthèse de médicaments à activité anticancéreuse, antimicrobienne et anti-inflammatoire. Leurs dérivés présentent des modifications structurelles qui optimisent leur biodisponibilité et leur sélectivité, permettant ainsi le développement de nouveaux principes actifs pour diverses applications thérapeutiques. Ces composés sont utilisés dans la fabrication d’API destinés au traitement du cancer, des infections, des maladies neurodégénératives et cardiovasculaires. De plus, les dérivés de quinazoline et de quinoléine sont essentiels dans la recherche d’inhibiteurs enzymatiques et dans la conception de molécules bioactives innovantes.
Chez CymitQuimica, nous proposons des dérivés de quinazoline et de quinoléine de haute pureté pour des applications en synthèse chimique, développement pharmaceutique et biotechnologie.
65578 produits trouvés pour "Dérivés de Quinazoline et de Quinoléine"
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2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
CAS :Formule :C13H9FN2O4Couleur et forme :Off White PowderMasse moléculaire :276.22rac N-Methyl Epinephrine-d6 Hydrochloride (>90%)
CAS :Produit contrôlé<p>Applications Labelled N-Methylepinephrine, the N-methylated analogue of the sympathomimetic hormone Epinephrine (E588585). Recent studies suggest that N-Methylepinephrine may be synthesized from Epinephrine by phenylethanolamine N-methyltransferase present in the brain.<br>References Kajita, M. et al.: Nip. Iyo Masu Sup. Gak. Kon., 19, 107 (1994); Plummer, C.J. et al.: Eur. J. Med. Chem., 148, 481 (1988);<br></p>Formule :C10H9D6NO3•HClDegré de pureté :>90%Couleur et forme :Off-White To Light GreenMasse moléculaire :203.273646p-Nitrophenyl 2-(Furfurylsulfinyl)acetate
CAS :Produit contrôlé<p>Stability Moisture Sensitive<br>Applications p-Nitrophenyl 2-(Furfurylsulfinyl)acetate is a furfurylsulfinyl derivative with gastroprotective activity. p-Nitrophenyl 2-(Furfurylsulfinyl)acetate is used in the preparation of histamine H2-receptor antagonist.<br>References Hirakawa, N. et al.: Chem. Pharmac. Bull., 46, 616 (1998); Zhu, R. et al.: Hef. Gong. Dax. Xue. Zir. Kex., 28, 1346 (2005);<br></p>Formule :C13H11NO6SCouleur et forme :BeigeMasse moléculaire :309.294-(2-Pyridinyl)benzaldehyde
CAS :Produit contrôlé<p>Impurity Atazanavir Impurity (Pyridinyl Benzaldehyde)<br>Applications Reactive metabolite of atazanavir. Atazanavir Impurity; Pyridinyl Benzaldehyde impurity<br>References F. Li et al., Drug Metabolism and Disposition 39, 294 (2011)<br></p>Formule :C12H9NOCouleur et forme :NeatMasse moléculaire :183.212-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
CAS :<p>Applications 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug.<br>References Wade, K., et al.: J. Pharmacol. Biomed. Anal., 8, 401 (1990), Hazuda, D., et al.: Science, 287, 646 (2000), Williams, J., et al.: Drug Metab. Dispos., 32, 1201 (2004), Duckett, C., et al.: Xenobiotica, 36, 59 (2006), Miners, J., et al.: Biochem. Pharmacol., 71, 1531 (2006), Summa, V., et al.: J. Med. Chem., 49, 6646 (2006),<br></p>Formule :C20H23FN6O6Couleur et forme :Off-WhiteMasse moléculaire :462.43Benzo[b]thien-2-yl Ketone (Zileuton Impurity)
CAS :Produit contrôlé<p>Applications Benzo[b]thien-2-yl ketone is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs).<br>References Israel, E., et al.: JAMA, 275, 931 (1996); Mahboobi, S., et al.: J. Med. Chem., 45, 1002 (2002); Mitschke, U. & Bäuerle, P.: J. Chem. Soc. Perk. Trans., 1, 740 (2001); Nenajdenko, V., et al.: Russ. Chem. Bull., 61, 1456 (2012)<br></p>Formule :C17H10OS2Couleur et forme :NeatMasse moléculaire :294.39Paliperidone N-Oxide
CAS :Produit contrôlé<p>Impurity Paliperidone USP Related Compound D<br>Applications One of the major degradation product of Risperidone in bulk drug and pharmaceutical dosage forms. Paliperidone USP Related Compound D.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leysen, J., et al.: J. Pharmacol. Exp. Ther., 247, 661 (1988), Huang, M., et al.: Pharm. Drug Dispos., 54, 257 (1993), Smyth, W., et al.: Anal. Bioanal. Chem., 378, 1305 (2004),<br></p>Formule :C23H27FN4O4Couleur et forme :NeatMasse moléculaire :442.48N-Nitroso Tetrahydrofuroylpiprazine
CAS :Produit contrôléFormule :C9H15N3O3Couleur et forme :NeatMasse moléculaire :213.234(R)-Propranolol-d7 Hydrochloride
CAS :Produit contrôlé<p>Applications The labelled R-enantiomer of Propranolol (P831800). β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).<br>References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),<br></p>Formule :C16H15D7ClNO2Couleur et forme :NeatMasse moléculaire :302.85a,a,a-Trifluorotoluene
CAS :Produit contrôlé<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formule :C7H5F3Couleur et forme :ColourlessMasse moléculaire :146.11Ticagrelor Sulfone
CAS :Produit contrôlé<p>Applications Ticagrelor Sulfone is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formule :C23H28F2N6O6SCouleur et forme :NeatMasse moléculaire :554.574'-Desmethoxy-4'-chloro Moxonidine
CAS :Produit contrôlé<p>Impurity Moxonidine<br>Applications 4'-Desmethoxy-4'-chloro Moxonidine is an impurity of moxonidine.<br>References Milovanovic, S., et al.: J. Pharm. Biomed. Anal., 59, 151 (2012); Filipic, S., et al.: J. Liquid Chromatogr. Related Technol., 38, 1121 (2015)<br></p>Formule :C8H9Cl2N5Couleur et forme :NeatMasse moléculaire :246.10Ethyl (2R,4S)-4-Methylpipecolate, 90%
CAS :Produit contrôlé<p>Applications Ethyl (2R,4S)-4-Methylpipecolate is an intermediate in the preparation of Argatroban (A769000).<br>References Hilpert, K. et al.: J. Med. Chem., 37, 3889 (1994), Kim, K. et al.: Med. Chem. Res., 6, 377 (1996),<br></p>Formule :C9H17NO2Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :171.24Furagin-13C3
Produit contrôlé<p>Applications Furagin-13C3 is the isotope labelled analogue of the antibacterial Furagin (F863000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Agace, W., et al.: J. Clin. Invest., 92, 780 (1993); Lawrenson, R., et al.: J. Antimicrob. Chemother., 48, 895 (2001); Dalhoff, A., et al.: Lancet Infect. Dis., 3, 359 (2003); Thumbikat, P., et al.: J. Immunol., 176, 3080 (2006);<br></p>Formule :C713C3H8N4O5Couleur et forme :NeatMasse moléculaire :267.17Dronedarone-d6 Hydrochloride
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>Formule :C31H39D6ClN2O5SCouleur et forme :NeatMasse moléculaire :599.25Indomethacin Acyl-β-D-glucuronide (>90%)
CAS :Produit contrôlé<p>Applications Indomethacin Acyl-β-D-glucuronide is a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995), Gamage, N., et al.: Toxicol. Sci., 90, 5 (2006), Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (2007), Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (2008),<br></p>Formule :C25H24ClNO10Couleur et forme :NeatMasse moléculaire :533.91NAP 226-90-d6
CAS :Produit contrôléFormule :C102H6H9NOCouleur et forme :NeatMasse moléculaire :171.27N-Desethyl N-Methyl Rivastigmine
CAS :Produit contrôlé<p>Impurity Rivastigmine EP Impurity B<br>Applications N-Desethyl N-Methyl Rivastigmine (Rivastigmine EP Impurity B) is an impurity of Rivastigmine (R541000), a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formule :C13H20N2O2Couleur et forme :NeatMasse moléculaire :236.32ZK 159222
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications ZK 159222 is a vitamin D receptor antagonist. It is a derivative of Vitamin D3 (V676045).<br>References Mizwicki, M., et al.: J. Bio. Chem., 284, 36292 (2009); Ochiai, E., et al.: Mol. Endocrinol., 19, 1147 (2005)<br></p>Formule :C32H48O5Couleur et forme :NeatMasse moléculaire :512.72rac-trans-7-Hydroxy Pramipexole
CAS :Produit contrôlé<p>Impurity Pramipexole Related Compound F<br>Applications Pramipexole derivative used for the preparation of (S)-Pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives.<br>References Validation of a column liquid chromatographic method for the analysis of pramipexole and its 5 impurities. Journal of AOAC International (2010), 93(4), 1102-1112. Gegoe, Csaba Lehel; Fejes, Imre; Garaczi, Sandor; Kovacs, Imre; Lukacs, Ferenc; Majercsik, Orsolya; Schneider, Geza. Process for preparation of (S)-pramipexole via resolution of 2,6-diamino-7-hydroxy-4,5,6,7-tetrahydrobenzothiazole derivatives. Eur. Pat. Appl. (2008), 26pp. CODEN: EPXXDW EP 1878731<br></p>Formule :C10H17N3OSCouleur et forme :NeatMasse moléculaire :227.33Olanzapine Lactam Impurity
CAS :<p>Impurity Olanzapine ketolactam impurity<br>Applications A degradation product of Olanzapine (LY170053) (O253750) in solid oral formulations.<br>References Chakrabarti, J., et al.: J.Med. Chem., 25, 1133 (1982), Chafetz, L., et al.: J. Pharm. Sci., 73, 1186 (1984), Hartauer, K., et al.: Pharm. Dev. Technol., 5, 303 (2000),<br></p>Formule :C17H20N4O2Couleur et forme :NeatMasse moléculaire :312.37N-Ethyl-3-buteno-o-toluidide
CAS :Produit contrôléFormule :C13H17NOCouleur et forme :NeatMasse moléculaire :203.28Zuclopenthixol (1 mg/mL In Methanol)
CAS :Formule :C22H25ClN2OSCouleur et forme :Single SolutionMasse moléculaire :400.96Dimethylamine (40% aq.)
CAS :Produit contrôlé<p>Applications Dimethylamine (40% aq.) is a compound often used in industry as a precursor to Nitrosodimethylamine (N525625), a potent carcinogen that is produced during disinfection of wastewater effluent, and is also present in trace amounts in food and polluted air. Dimethylamine is also present in human urine and can be indicative of certain disorders.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gereke, A. & Sedlak, D.: Env. Sci. Tech., 37, 1331 (2003); Mitch, W., et al.: Env. Eng. Sci., 20, 389 (2003); Tsikas, D., et al.: J. Chromatogr. B, 851, 229 (2007)<br></p>Formule :C2H7NCouleur et forme :NeatMasse moléculaire :45.084-Chlorophenothiazine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Prochlorperazine (P755800) and related compound.<br></p>Formule :C12H8ClNSCouleur et forme :NeatMasse moléculaire :233.72rac N-Desmethyl Mephenytoin-D5 (Major)
CAS :Produit contrôlé<p>Applications An anticonvulsant, hypnotic. A labelled metabolite of Mephentoin.A representative lot was 85% d5; 15% d4 1% d3 with no detectable d0.<br>References Karlaganis, G., et al.: Drug Metab. Dispos., 8, 173 (1980), Knabe, J., et al.: Arch. Phar., 313, 538 (1980),<br></p>Formule :C112H5H7N2O2Couleur et forme :NeatMasse moléculaire :209.26Erismodegib
CAS :Produit contrôlé<p>Applications A potent, selective and orally bioavailable Smoothened (SMO) antagonist; it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO). Antineoplastic. Potent Hedgehog inhibitor.<br>References Berman, D., et al.: Science, 297, 1559 (2002), Varjosalo, M., et al.: Cell, 133, 537 (2008), Theunissen, J., et al.: Cancer Res., 69, 6007 (2009),<br></p>Formule :C26H26F3N3O3Couleur et forme :NeatMasse moléculaire :485.501-(2,5-Dimethylphenyl)ethanol
CAS :Produit contrôlé<p>Applications 1-(2,5-Dimethylphenyl)ethanol can be used as a reagent in reactions or as a aroma compound<br>References Zhou, J., et al.: Yuanyi Xuebao., 37, 1621-1628 (2010)<br></p>Formule :C10H14OCouleur et forme :NeatMasse moléculaire :150.22N-Desethyl N-Methyl rac-Rivastigmine
CAS :<p>Impurity Rivastigmin USP Related Compound B<br>Applications N-Desethyl N-Methyl rac-Rivastigmine (Rivastigmin USP Related Compound B) is an impurity in the synthesis of Rivastigmine (R541000) a brain selective acetylcholinesterase inhibitor. Nootropic.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993),<br></p>Formule :C13H20N2O2Couleur et forme :Clear ColourlessMasse moléculaire :236.313-[2-[4-(6-Fluoro-2-benzoxazolyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone Impurity)
CAS :Produit contrôléFormule :C23H27FN4O2Couleur et forme :NeatMasse moléculaire :410.485’-Hydroxyphenyl Carvedilol
CAS :<p>Applications A metabolite of Carvedilol (C184625). It is used in the treatment of hypertension.<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Formule :C24H26N2O5Couleur et forme :NeatMasse moléculaire :422.474-Hydroxy Propranolol β-D-Glucuronide (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications A metabolite of 4-Hydroxy propranolol. Antihypertensive; antianginal; antiarrhythmic (class II).<br>References Walle, T., et al.: Clin. Pharmacol. Ther., 46, 257 (1989), Christ, D.D., et al.: Drug Metab. Dispos., 18, 1 (1990),<br></p>Formule :C22H29NO9Couleur et forme :NeatMasse moléculaire :451.47Verapamil Ethyl Methanethiosulfonate, Bromide
CAS :Produit contrôlé<p>Applications An analog of Verapamil. P Glycoprotein drug binding domain verapamil methanethiosulfonate. Useful for mapping the pore region of L-type calcium channels and Kv1.3 potassium channels.<br>References Loo, T., et al.: J. Biol. Chem., 270, 843 (1995), Sharom, F., et al.: J. Membr. Biol., 160, 161 (1997), Kim, R., et al.: J. Clin. Invest., 101, 289 (1998), Lee, C., et al.: Biochemistry., 37, 3594 (1998),<br></p>Formule :C30H45N2O6S2·BrCouleur et forme :NeatMasse moléculaire :673.72N-(4-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS :Produit contrôlé<p>Applications Intermediate in the preparation of Imatinib impurities. It is a COVID19-related research product.<br></p>Formule :C16H15N5Couleur et forme :NeatMasse moléculaire :277.32N-Desmethyl 4-Benzyloxy Toremifene Hydrochloride
CAS :Produit contrôlé<p>Applications Toremifene (T547500) derivative. A triphenylalkene derivative with anti-estrogenic, and anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C32H33Cl2NO2Couleur et forme :NeatMasse moléculaire :534.52N-tert-Butyl-3-isopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide
CAS :Produit contrôlé<p>Applications N-tert-Butyl-3-isopropyl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxamide is a metabolite of Amicarbazone (A605040); a triazolinone herbicide with a broad spectrum of weed control.<br>References Dayan, F., et al.: Weed Science, 57, 579 (2009); Elmore, M., et al.: Weed Technol., 27, 596 (2013); Dong, M., et al.: J. Sep. Sci., 38, 2245 (2015)<br></p>Formule :C10H18N4O2Couleur et forme :White To Off-WhiteMasse moléculaire :226.28Everolimus Isomer C (>60%, contains everolimus)
CAS :Produit contrôlé<p>Stability Unstable in solution, revert back to Everolimus<br>Applications Everolimus Isomer C is an isomer of Everolimus (E945400), a derivative of Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001); Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001); Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002)<br></p>Formule :C53H83NO14Couleur et forme :NeatMasse moléculaire :958.222-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid
CAS :Produit contrôlé<p>Applications 2-((3-Fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoic acid (cas# 1289942-66-0) is a useful research chemical.<br></p>Formule :C12H15FN2O3Couleur et forme :NeatMasse moléculaire :254.2631-Oxo Everolimus (~80%)
Produit contrôléFormule :C53H81NO14Degré de pureté :~80%Couleur et forme :NeatMasse moléculaire :956.215-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS :Produit contrôlé<p>Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).<br>References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);<br></p>Formule :C14H11F3O5Couleur et forme :NeatMasse moléculaire :316.232-Cyano-3-(3-chlorophenylethyl)pyridine
CAS :Produit contrôléFormule :C14H11ClN2Couleur et forme :NeatMasse moléculaire :242.706,8-Dioxo Apalutamide
CAS :Produit contrôlé<p>Applications 6,8-Dioxo Apalutamide is an impurity of Apalutamide (A726120). Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Formule :C21H15F4N5O3Couleur et forme :NeatMasse moléculaire :461.38rac O-Acetyl Pseudoephedrine Hydrochloride
CAS :Produit contrôlé<p>Applications rac O-Acetyl Pseudoephedrine is a racemic O-acetylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350).<br>References Snopek, J. et al.: J. Chrom., 438, 211 (1988);<br></p>Formule :C12H17NO2·ClHCouleur et forme :WhiteMasse moléculaire :243.73Nitroso Valsartan Methyl Ester
CAS :Produit contrôlé<p>Applications Nitroso Valsartan Methyl Ester is an impurity of Valsartan (V095750) a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Formule :C20H22N6O3Couleur et forme :NeatMasse moléculaire :394.4272,4-Difluorobenzoic Acid
CAS :Produit contrôlé<p>Applications 2,4-Difluorobenzoic Acid (cas# 1583-58-0) is a compound useful in organic synthesis.<br></p>Formule :C7H4F2O2Couleur et forme :NeatMasse moléculaire :158.10(7-(4-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one)
CAS :Produit contrôlé<p>Impurity Aripiprazole USP Related Compound H<br>Applications (7-(4-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}butoxy)-3,4-dihydroquinolin-2(1H)-one) is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Aripiprazole USP Related Compound H.<br>References Zeidan, T.A., et al.: Crystal. Growth. Design., 13, 2036 (2013); Nagasaka, Y., et al.: Biopharma. Drug. Dispo., 33, 304 (2012); Chen, X., et al.: J. Med. Chem., 55, 7141 (2012);<br></p>Formule :C27H35Cl2N3O3Couleur et forme :WhiteMasse moléculaire :520.49De(methypiperazinyl) Sildenafil Dimer Impurity
CAS :Produit contrôlé<p>Applications A related dimeric impurity of Sildenafil (S435000).<br></p>Formule :C34H38N8O6SCouleur et forme :NeatMasse moléculaire :686.78rac 4-(3-Aminobutyl)phenol
CAS :Produit contrôlé<p>Applications A metabolite of the antihypertensive agent, Labetalol (L096500).<br>References Gal, J., et al.: Res. Comm. Chem. Pathol. Pharmacol., 62, 3 (1988),<br></p>Formule :C10H15NOCouleur et forme :NeatMasse moléculaire :165.23rac O-Desmethyl Naproxen-d3
CAS :Produit contrôléFormule :C13D3H9O3Couleur et forme :Dark RedMasse moléculaire :219.25Argatroban
CAS :Produit contrôlé<p>Applications Synthetic thrombin inhibitor. Antithrombotic.<br>References Abiko, Y., et al.: Thromb. Res., 24, 285 (1981), Kikumoto, R., et al.: Biochemistry, 23, 85 (1984),<br></p>Formule :C23H36N6O5SCouleur et forme :White PowderMasse moléculaire :508.63Isopropyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam Impurity I)
CAS :Produit contrôlé<p>Impurity Piroxicam EP Impurity I<br>Applications Piroxicam impurity I.<br>References Lombardino, J., et al.: J. Med. Chem., 14, 1171 (1971), Turck, D., et al.: Clin. Drug Invest., 9, 270 (1995),<br></p>Formule :C12H13NO5SCouleur et forme :NeatMasse moléculaire :283.31,3-Bis(bromomethyl)-5-methylbenzene
CAS :Produit contrôlé<p>Impurity Anastrozole 1,3-Dibromomethyl Impurity<br>Applications 1,3-Bis(bromomethyl)-5-methylbenzene is a reagent used in the synthesis of sphingosine kinase 2 inhibitors. Anastrozole 1,3-Dibromomethyl Impurity<br>References Congdon, M. et al.: Bioorg. Med. Chem. Lett., 25, 4956 (2015);<br></p>Formule :C9H10Br2Couleur et forme :NeatMasse moléculaire :277.982-(1-aminocyclohexyl)acetic acid
CAS :Produit contrôléFormule :C8H15NO2Couleur et forme :NeatMasse moléculaire :157.21Tipiracil Hydrochloride
CAS :Produit contrôlé<p>Applications Tipiracil Hydrochloride serves as a treatment for metastatic colorectal cancer (mCRC). A thymidine phosphorylase inhibitor.<br>References Sugita, K., et al.: Oncol., 91, 224-230 (2016); van der Velden, D. L., et al.: Clin. Cancer Res., 22, 2835-2839 (2016)<br></p>Formule :C9H11ClN4O2·(HCl)Couleur et forme :White To Off-WhiteMasse moléculaire :242.66 + (36.46)2,2’-Methylene Bis[Ranitidine]
CAS :Produit contrôlé<p>Impurity Ranitidine EP Impurity I<br>Stability Light Sensitive, Temperature Sensitive<br>Applications 2,2’-Methylene Bis[Ranitidine] (Ranitidine EP Impurity I) is an impurity of histamine H2-receptor antagonist Ranitidine (R120000).<br>References Jones, M.D. et al.: J. Sep. Sci., 29, 2409 (2006); Kelly, M.A. et al.: J. Chrom. A, 798, 297 (1998);<br></p>Formule :C27H44N8O6S2Couleur et forme :NeatMasse moléculaire :640.82Varenicline-d2,15N2 Dihydrochloride
CAS :Produit contrôlé<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Formule :C13H13D2Cl2N15N2Couleur et forme :Light Beige SolidMasse moléculaire :288.18Methyl 5,6,7,8-Tetradehydro Risperidone
CAS :Produit contrôlé<p>Applications An internal standard for Risperidone (R525000).<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Formule :C24H25FN4O2Couleur et forme :White To Off WhiteMasse moléculaire :420.481,3-Dichloroacetone
CAS :Produit contrôlé<p>Applications 1,3-Dichloroacetone (cas# 534-07-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C3H4Cl2OCouleur et forme :NeatMasse moléculaire :126.97N’-Benzylidene-2-ethoxybenzimidohydrazide Hydroiodide
Produit contrôléFormule :C16H17N3O·HICouleur et forme :Off-WhiteMasse moléculaire :395.238Deschloro-4’-chloro Clomiphene Hydrochloride
CAS :Produit contrôlé<p>Applications An impurity of Clomiphene (C587025).<br></p>Formule :C26H29Cl2NOCouleur et forme :NeatMasse moléculaire :442.424-Oxo-1,4-dihydroquinoline Carboxylic Acid
CAS :Produit contrôlé<p>Applications 4-Oxo-1,4-dihydroquinoline Carboxylic Acid is a novel HIV-1 integrase strand transfer inhibitor.<br>References Shinkai, H. et al.: Antivir. Drugs. 197 (2011); Liao, C. et al.: ChemMedChem., 5, 1053 (2010);<br></p>Formule :C10H7NO3Couleur et forme :NeatMasse moléculaire :189.17Hydrolyzed Pomalidomide M10
CAS :Produit contrôlé<p>Applications Hydrolyzed Pomalidomide M10 is an impurity of pomalidomide (P688200), which is a thalidomide derivative, a potent inhibitor of TNF-α production. It is an antiinflammatory and antitumor agent used in the treatment of multiple myeloma.<br>References Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Formule :C13H13N3O5Couleur et forme :NeatMasse moléculaire :291.26Iproniazid
CAS :Produit contrôlé<p>Applications Iproniazid is a hydrazine based drug used as an antidepressant. Iproniazid acts as an irreversible and nonselective monoamine oxidase inhibitor.<br>References Fagervall, I. et al.: Biochem. Pharmacol., 35, 1381 (1986); Horita, A.: Princ. Psychopharmacol., 279 (1970); O'Donnell, J.M. et al.: Psychopharmacology, 78, 214 (1982);<br></p>Formule :C9H13N3OCouleur et forme :White SolidMasse moléculaire :179.225-(2-Fluorophenyl)-5-oxovaleric Acid
CAS :Produit contrôlé<p>Applications 5-(2-Fluorophenyl)-5-oxovaleric Acid is used as a reagent in the preparation of indole derivatives which act as cell protective agents. It is also used as a reagent in the catalytic N-nitroso aldol reaction of γ,δ-unsaturated δ-lactones.<br>References Yamamoto, I., et al.: Preparation of indole derivatives as cell protective agents, WO Patent 9745410, Dec 4, 1997; Yanagisawa, A., et al.: Org. Lett., 14, 2434 (2012);<br></p>Formule :C11H11FO3Couleur et forme :NeatMasse moléculaire :210.2α,α'-Diethyl-4,4'-stilbenediol-d4
CAS :Produit contrôlé<p>Applications α,α'-Diethyl-4,4'-stilbenediol-d4 is an intermediate in the synthesis of d in the synthesis of isotope labelled metabolites of Diethylstibestrol (D445026).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schuller, P.L., et al.: J. Chromatograph., 31, 237 (1967);<br></p>Formule :C18H16D4O2Couleur et forme :NeatMasse moléculaire :272.37Nicoboxil
CAS :Produit contrôlé<p>Applications Nicoboxil is a medication used in the treatment of acute non-specific low back pains.<br>References Gaubitz, M., et al.: Eur. J. Pain , 20, 263 (2016),<br></p>Formule :C12H17NO3Couleur et forme :ColourlessMasse moléculaire :223.275-Acetyl-2-propyl-1H-Imidazole-4-carboxylic Acid Ethyl Ester
CAS :Produit contrôlé<p>Applications 5-Acetyl-2-propyl-1H-Imidazole-4-carboxylic Acid Ethyl Ester is used in the synthetic preparation of imidazole-5-carboxylic acids bearing alkyl, alkenyl, and hydroxyalkyl substituents at the 4-position and their related compounds.<br>References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996);<br></p>Formule :C11H16N2O3Couleur et forme :NeatMasse moléculaire :224.26N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide
CAS :Produit contrôlé<p>Applications N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide was used in the study to discover a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. N-[4-[[(Z)-(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)phenylmethyl]amino]phenyl]-N,4-dimethyl-1-piperazineacetamide is an impurity of Intedanib (I666650), which is an antitumor agent.<br>References Edupuganti, R., et al.: Bioorg. Med. Chem., 25, 2609 (2017); Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formule :C29H31N5O2Couleur et forme :NeatMasse moléculaire :481.59Ezetimibe-13C6
CAS :Produit contrôlé<p>Applications Labelled Ezetimibe (E975000), an antihyperlipoproteinemic. A Cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Formule :C1813C6H21F2NO3Couleur et forme :NeatMasse moléculaire :415.38Benzoin
CAS :Produit contrôlé<p>Applications Benzoin has been used as a catalyst in photoinitiation.<br>References Voll, D., et. al.: Macromolecules, 44, 2542 (2011)<br></p>Formule :C14H12O2Couleur et forme :Off-WhiteMasse moléculaire :212.244-Desfluoro-3-Fluoro Bicalutamide
CAS :Produit contrôlé<p>Impurity Bicalutamide USP Related Compound B/ Bicalutamide EP Impurity B<br>Applications 3-Fluorophenyl Bicalutamide (Bicalutamide USP Related Compound B) is a steroisomer of Bicalutamide (B382000), non-steroidal peripherally active anti-androgen. Used as an antiandrogen, antineoplastic (hormonal).<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Formule :C18H14F4N2O4SCouleur et forme :NeatMasse moléculaire :430.37Eltenac-13C,d3
CAS :Produit contrôlé<p>Applications Labelled Eltenac (E507000). A nonsteroidal anti-inflammatory drug.<br>References Allen, A., et al.: Gut, 21, 249 (1980), Tobin, T., et al.: J. Vet. Pharmacol. Therap., 9, 1 (1986),<br></p>Formule :CC11H7Cl2D2NO2SCouleur et forme :NeatMasse moléculaire :302.184-(Diphenylmethyl)-1-nitrosopiperidine
CAS :Produit contrôléFormule :C18H20N2OCouleur et forme :NeatMasse moléculaire :280.374-Nitrothalidomide
CAS :<p>Applications 4-Nitrothalidomide is a compound involved in the preparation of Pomalidomide (P688200), a thalidomide derivative and potent inhibitor of TNF-α production.<br>References Huang, D., et al.: Syn. Comm., 46, 1343-1348 (2016); Ruchelman, A. et al.: Bioorg. Med. Chem. Lett., 23, 360 (2013); Latif, T. et al.: Exp. Hematol. Oncol., 1, 27 (2012); Man, H. et al.: Bioorg. Med. Chem. Lett., 13, 3415 (2003); Muller, G. et al.: Bioorg. Med. Chem. Lett., 9, 1625 (1999)<br></p>Formule :C13H9N3O6Couleur et forme :NeatMasse moléculaire :303.23Loratadine-d5 (ethyl-d5)
CAS :Produit contrôlé<p>Applications Loratadine-d5 (ethyl-d5) (CAS# 1398065-63-8) is a useful isotopically labeled research compound.<br></p>Formule :C22D5H18ClN2O2Couleur et forme :NeatMasse moléculaire :387.92Telmisartan Amide
CAS :<p>Impurity Telmisartan EP Impurity F / Telmisartan Amide<br>Applications An amide impurity of Temisartan (D294250).<br>References Xu, G. et al.: Zhong. Yiyao Gong. Zaz., 40, 714 (2009);<br></p>Formule :C33H31N5OCouleur et forme :NeatMasse moléculaire :513.63Azilsartan Imidazole Carbonyl Dioxolene Ester
CAS :<p>Applications Azilsartan Imidazole Carbonyl Dioxolene Ester is an impurity of Azilsartan (A926900), an analgesic and antiinflammatory drugs containing angiotensin II antagonists.<br>References Kohara, Y., et al.: J. Med. Chem., 39, 5228 (1996), Plomgaard, P., et al.: Diabetes, 54, 2939 (2005), Fenton, C., et al.: Drugs, 2005, 65, 537,<br></p>Formule :C33H28N6O8Couleur et forme :NeatMasse moléculaire :636.61Losartan Trityl Ether
CAS :<p>Impurity Losartan EP Impurity I<br>Applications Losartan Trityl Ether (Losartan EP Impurity I) is an impurity of Losartan.<br>References Duncia, J.V., et al.: J. Med. Chem., 33, 1312 (1990),<br></p>Formule :C41H37ClN6OCouleur et forme :NeatMasse moléculaire :665.23Haloperidol Decanoate N-Oxide
Produit contrôléFormule :C31H41ClFNO4Couleur et forme :NeatMasse moléculaire :546.11N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide
CAS :Produit contrôlé<p>Impurity Ranolazine USP Related Compound D<br>Applications N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide is an intermediate of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. Ranolazine is also known to exert antianginal activities.<br>References Sampath, A., et al.: Org. Proc. Rsch. Dev., 16, 748 (2012); Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004); McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998); Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002)<br></p>Formule :C24H32N4O2Couleur et forme :NeatMasse moléculaire :408.541-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxaldehyde oxime
CAS :<p>1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarboxaldehyde oxime is an impurity in the drug product of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran. It is a metabolite that is formed during the metabolism of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofuran by cytochrome P450 enzymes. The CAS number for this compound is 227954–88–3. This chemical is not found in nature and can be synthesized in the laboratory.</p>Formule :C20H23FN2O2Degré de pureté :Min. 95%Masse moléculaire :342.41 g/molRisperidone E-oxime impurity
CAS :<p>Risperidone E-oxime impurity is a drug product that has been studied for its metabolism in humans, animals and plants. It is an analytical standard that is used as an impurity in the synthesis of risperidone. Risperidone E-oxime impurity is also a synthetic compound with CAS No. 691007-09-7. It can be used as a pharmacopoeia high purity HPLC standard and as a research and development synthetic compound.</p>Formule :C23H28F2N4O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :430.49 g/molSalmeterol Dimer Impurity (Mixture of Diastereomers)
CAS :<p>Salmeterol dimer impurity is a drug product. It is a custom synthesis with high purity. The metabolite of this compound is salmeterol, which is an active ingredient in the asthma medication Serevent (salmeterol xinafoate). Salmeterol dimer impurity has been shown to be a natural metabolite of salmeterol. Salmeterol dimer impurity has also been shown to have anti-inflammatory properties. This compound can be found as an analytical standard for HPLC and used for research and development purposes.</p>Formule :C50H72N2O7Degré de pureté :Min. 95%Masse moléculaire :812.533952-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran
CAS :<p>2-Butyl-3-(3,5-diiodo-4-hydroxybenzoyl)benzofuran is a benzofuran. It is a yellow solid that can be dissolved in water and alcohol.</p>Formule :C19H16I2O3Degré de pureté :Min. 95%Masse moléculaire :546.14 g/mol[4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone
CAS :<p>4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone (CAS No. 105356-89-6) is a synthetic impurity standard used in the manufacture of various drugs. Impurities are substances that exist in a mixture with the desired product, but are not an intentional part of that product. Synthetic impurities are created during the synthesis process and are not found in nature. This substance has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase, and is excreted through urine and bile. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formule :C18H23N5O4Degré de pureté :Min. 95%Masse moléculaire :373.41 g/mol3-(Dimethylamino)-1-(2-thienyl)propan-1-ol
CAS :<p>3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is an organic compound that is used as a chiral building block in the synthesis of drugs. It is not currently used in any known drug, but it has been shown to be racemized at high temperatures. 3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is also a byproduct of pollution and can be found in the environment where it may be degraded by bacteria.</p>Formule :C9H15NOSDegré de pureté :Min. 95%Masse moléculaire :185.29 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid
CAS :<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxylic acid (4BMBCA) is a chemical compound that is used as an analytical method in drug discovery and development. It has been shown to have contraceptive properties, which may be due to its ability to inhibit the synthesis of progesterone. 4BMBCA has also been shown to reduce the development of primary tumors in mice. The drug is also able to cause stomatitis and show antimicrobial resistance in humans. Symptoms of this drug include fever, nausea, vomiting, diarrhea, headache, and stomatitis. 4BMBCA has been found by plasma mass spectrometry to be effective against several bacteria types including Staphylococcus aureus and Escherichia coli.</p>Formule :C14H11BrO2Degré de pureté :Min. 95%Masse moléculaire :291.14 g/mol10-Oxo mirtazapine
CAS :<p>10-Oxo mirtazapine is a metabolite of the antidepressant drug mirtazapine. It is an impurity in the HPLC standard for mirtazapine and has been shown to be pharmacologically active in animal models. 10-Oxo mirtazapine has also been found to be an impurity in other drugs, such as fluoxetine hydrochloride, but it is not known if it has any activity.</p>Formule :C17H17N3ODegré de pureté :Min. 95%Masse moléculaire :279.34 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid benzyl ester hydrobromide
CAS :<p>2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a drug product that is used as an analytical reference standard for the identification of impurities in aminoglycosides. 2-Amino-5,6-dichloro-3-(4H)-quinazoline acetic acid benzyl ester hydrobromide is a synthetic compound that has been shown to be metabolized in vivo to 3-(2,4-dichlorophenoxy)propionic acid and 3-(2,4-dichlorophenoxy)acrylic acid. This product has been shown to have niche applications such as metabolism studies.</p>Formule :C17H15Cl2N3O2Degré de pureté :Min. 95%Masse moléculaire :364.23 g/molBrexpiprazole impurity 3
CAS :<p>Brexpiprazole impurity 3 is a drug product that has been custom synthesized for research purposes. The purity of this product is high and it has been analyzed using analytical methods. This product can be used to study the metabolism of brexpiprazole, which is an atypical antipsychotic medication. Brexpiprazole impurity 3 also has pharmacopoeia standards, which can be used to develop new drugs or as a quality control standard in research and development.</p>Formule :C25H27N3O3SDegré de pureté :Min. 95%Masse moléculaire :449.57 g/mol3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide
CAS :<p>3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide is a drug product that is custom synthesized. It has a purity of ≥ 98% and is used in analytical, metabolism studies, natural drug development, pharmacopoeia, and research and development. 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide has an impurity standard of 5% and can be found under CAS No. 90237-03-9.</p>Formule :C8H15N7O3S3Degré de pureté :Min. 95%Masse moléculaire :353.45 g/mol(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS :<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>Formule :C15H15NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :209.29 g/molN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride
CAS :<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.</p>Formule :C14H17N5O2·HClDegré de pureté :Min. 95%Masse moléculaire :323.78 g/molCaptopril EP Impurity N
CAS :<p>Captopril EP Impurity N is a synthetic impurity found in Captopril EP, which is used as a drug product for the treatment of hypertension. The impurity standard for Captopril EP Impurity N is available on request.</p>Formule :C8H14O4S2Degré de pureté :Min. 95%Masse moléculaire :238.33 g/molDi-destriazole anastrozole dimer impurity
CAS :<p>Di-destriazole anastrozole dimer impurity is a synthetic impurity that is created during the synthesis of anastrozole. It has been studied as a possible metabolite of the drug, but its role in metabolism is not well understood. Di-destriazole anastrozole dimer impurity is soluble in water and methanol and has a melting point of between 1°C to 2°C. The purity of this compound is typically at least 99% with a specific gravity of 1.043 g/mL.</p>Formule :C26H29N3Degré de pureté :Min. 95%Masse moléculaire :383.53 g/molAnastrozole dimer impurity - 65%
CAS :<p>Anastrozole is an aromatase inhibitor used in the treatment of breast cancer. It is a synthetic drug and impurity standard for HPLC analysis, pharmacopoeia monograph, and synthetic drug development. This product is a mixture of two stereoisomers - the active form, 4-hydroxyanastrozole (4HA), and the inactive form, 4-oxo-anastrozole (4OA). The purity of this product is >99% with a melting point of 130°C.</p>Formule :C30H31N9Degré de pureté :Min. 95%Masse moléculaire :517.63 g/mol1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone
CAS :<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-hydroxy-1-pentanone (DMPP) is an analog of the antiarrhythmic drugs flecainide and propafenone. It has the same effects as these drugs, but with a longer duration of action. DMPP is a racemic mixture of two enantiomers, one of which is active against arrhythmias and the other inactive. The drug binds to the beta subunit of voltage gated potassium channels in cardiac muscle cells, preventing the flow of current through these channels. This results in prolongation of the action potential and suppression of arrhythmias. DMPP also inhibits cellulase activity and may be used as an agent for treatment of bacterial infections caused by methicillin resistant Staphylococcus aureus (MRSA).</p>Formule :C19H27N5O4Degré de pureté :Min. 95%Masse moléculaire :389.45 g/molSolifenacin EP impurity F succinate
CAS :<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>Formule :C27H32N2O6Degré de pureté :Min. 95%Masse moléculaire :480.55 g/mol4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
CAS :<p>4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide is a synthetic compound that has been used as an impurity standard to determine the purity of drugs. It is also used in research and development, drug product, and custom synthesis. 4-Methyl-3-[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide has a CAS number of 851137-91-2 and is on the list of pharmacopoeias. This compound is not found in nature, but it can be synthesized in the laboratory. Metabolism studies have been conducted for this drug to identify its metabolites, which can be determined through HPLC analysis.</p>Formule :C17H15N5ODegré de pureté :Min. 95%Masse moléculaire :305.33 g/molRegorafenib metabolite M5
CAS :<p>Regorafenib metabolite M5 is a drug product that is custom synthesized by our company and has high purity. It can be used in metabolism studies, drug development, and pharmacopoeia due to its natural origin. It is also a synthetic compound that can be used as an impurity standard or research and development standard in HPLC.</p>Formule :C20H13ClF4N4O4Degré de pureté :Min. 95%Masse moléculaire :484.79 g/molRisperidone N-oxide
CAS :<p>Risperidone N-oxide is a prodrug of risperidone. It is prepared by reacting risperidone with methanol and hydrogen peroxide in the presence of piperidine, followed by purification using preparative high-performance liquid chromatography. Risperidone N-oxide is a crystalline solid with a melting point of about 190 °C. Risperidone N-oxide has been shown to have antiemetic properties, which may be due to its ability to block dopamine receptors in the brain. The drug also shows some antipsychotic activity, and it has a constant therapeutic effect against schizophrenia. The major impurities found in risperidone N-oxide are hydroxylamine and piperidine.</p>Formule :C23H27FN4O3Degré de pureté :Min. 95%Masse moléculaire :426.48 g/molN-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide
CAS :<p>N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide is a metabolite that is formed when the drug product, ticagrelor, undergoes metabolism in the liver. Ticagrelor is a prodrug that requires conversion to its active form, which is N-(3-hydroxytricyclo[3.3.1.1]dec-1-yl)glycyl-L-prolinamide, before it can be used as a platelet inhibitor and antiplatelet agent for the prevention of thrombotic events such as heart attack and stroke. It has been shown to have an excellent stability profile and high purity when produced by HPLC or synthesized using the latest methodology under GMP conditions.</p>Degré de pureté :Min. 95%Brexpiprazole impurity 2
CAS :<p>Brexpiprazole impurity 2 is a product of research and development. It is an impurity standard that can be custom-synthesized in high purity. This product is a synthetic, pharmacopoeia-grade drug product that can be used as a metabolite in metabolism studies or as a QC in analytical assays. Brexpiprazole impurity 2 has CAS No. 2094559-58-5, and is available in natural form. It is also available for HPLC analysis with a purity of 99%.</p>Formule :C38H40N4O4SDegré de pureté :Min. 95%Masse moléculaire :648.81 g/mol[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone
CAS :<p>6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone is a synthetic impurity standard that is used as a reference material in the analytical, natural and drug development, and metabolite studies. 6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone has a molecular weight of 390.27 and chemical formula C26H28N2O3S. It is also referred to by its CAS number 1391054-73-1.6</p>Formule :C28H27NO4SDegré de pureté :Min. 95%Masse moléculaire :473.58 g/mol(R)-Pramipexole 2HCl
CAS :Produit contrôlé<p>Dopamine (D2 and D3) receptor agonist; has anti-parkinsonian effects</p>Formule :C10H19Cl2N3SDegré de pureté :Min. 95%Masse moléculaire :283.06767Alfuzosin hydrochloride EP Impurity F hydrochloride
CAS :<p>Alfuzosin EP Impurity F hydrochloride is a drug product that is used as an analytical standard for Alfuzosin hydrochloride. It is a natural, synthetic, and impurity standard that exhibits similar chromatographic properties to the API. The CAS number of this impurity is 19216-68-3. This product has a niche market because it is used in metabolism studies. It also exhibits high purity and pharmacopoeia grade quality.</p>Formule :C12H16N4O2•HClDegré de pureté :Min. 95%Masse moléculaire :284.74 g/molAmido methyl meloxicam
CAS :<p>Amido methyl meloxicam is a synthetic nonsteroidal anti-inflammatory drug. It is used to relieve inflammation and pain. Amido methyl meloxicam is chemically similar to the naturally occurring substance, meclofenamic acid, but it does not have the same side effects.<br>Amido methyl meloxicam is metabolized in the liver by CYP3A4/5 and then excreted by the kidneys.</p>Formule :C15H15N3O4S2Degré de pureté :Min. 95%Masse moléculaire :365.43 g/mol4-Desmethyl-3-methyl celecoxib
CAS :<p>This compound is a drug product that is used as an analytical standard for the identification of impurities. This compound is also a Metabolism studies, Natural, API impurity, Custom synthesis, Impurity standard, Synthetic and Drug development research chemical. The CAS number for this compound is 170570-01-1 and it has HPLC standards with high purity. This compound is also a Synthetic and Pharmacopoeia Research Chemical with a niche market.</p>Formule :C17H14F3N3O2SDegré de pureté :Min. 95%Masse moléculaire :381.37 g/molDe(diethylaminoethyl-5-iodo) Amiodarone
CAS :<p>Amiodarone is a drug that belongs to the group of annular compounds. It has been used in the treatment of cardiac arrhythmias, such as atrial fibrillation (AF) and ventricular tachycardia (VT). Amiodarone has been shown to have a high affinity for specific genes, including those involved in the regulation of the heart. This drug is also used in animals, such as dogs and rats. Amiodarone has been shown to have toxic effects on cardiac tissue and other organs, which may be due to its ability to inhibit the metabolism of thyroid hormones by deiodination. Amiodarone also inhibits synthesis of protein by binding to DNA, inhibiting transcription and translation.</p>Formule :C19H17IO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :420.24 g/molSolifenacin impurity C
CAS :<p>Solifenacin impurity C is an impurity that is found in the drug product Solifenacin. It has been shown to be a natural metabolite and has been detected in human urine. Solifenacin impurity C is used as an analytical standard for HPLC analyses of solifenacin, and can also be used as a reference material for pharmacopoeia. The purity of this compound is 99%.</p>Formule :C31H28N2ODegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :444.57 g/mol3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride
CAS :Produit contrôlé<p>3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is a drug product that is used as an analytical standard. This drug development chemical is not found in nature and has been synthesized in the laboratory. The chemical's structure closely resembles that of amphetamine and methamphetamine. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride is used to develop analytical methods for determining impurities in APIs such as 3,4-dimethoxyamphetamine (DMA). It is also used to help identify metabolites of amphetamines. 3,4-Dimethoxy-N,N-dimethyl-benzeneethanamine hydrochloride has been shown to have a half life of approximately 12 hours and is excreted through the urine.</p>Formule :C12H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :245.75 g/mol[5-[(Dimethylamino)methyl]furan-2-yl]methanol
CAS :<p>Dimethylaminoethyl methacrylate is a chemical compound that belongs to the group of dimeric monomers. It is an activated form of methacrylates, which are compounds containing the -C(O)OC-CH2-CH2-O-CO-R functional group. The activated form is prepared by the reaction of a primary amine with acetic acid and acrylic acid. Dimethylaminoethyl methacrylate has been used as a carbohydrate adduct to create glycoconjugates and it has been shown to have anti-mutagenic properties. This product can be found in high concentrations in China.</p>Formule :C8H13NO2Degré de pureté :Min. 95%Masse moléculaire :155.19 g/mol1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS :<p>1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-methoxyethyl)phenoxy]-2-propanol] is a synthetic drug product that has been custom synthesized for testing purposes. It is one of the metabolites of the drug product 1,1'-[(1-Methylethyl)imino]bis[3-[4-(2-hydroxypropyl)phenoxy]-2-propanol]. The metabolite has not been found in nature and its structure is unknown. Metabolism studies have been performed on this metabolite to determine its metabolic pathway. This metabolite is an impurity standard for HPLC analysis.</p>Formule :C27H41NO6Degré de pureté :Min. 95%Masse moléculaire :475.62 g/molDutasteride EP impurity E
CAS :<p>Please enquire for more information about Dutasteride EP impurity E including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C27H30F6N2O2Degré de pureté :Min. 95%Masse moléculaire :528.54 g/molChlorhexidine dihydrochloride impurity B
CAS :<p>Chlorhexidine dihydrochloride impurity B is an impurity found in chlorhexidine dihydrochloride, a drug that is used as an antiseptic and disinfectant. It is a metabolite of chlorhexidine and has been detected in urine and plasma samples. This impurity has no known pharmacological activity. The purity of this compound is not less than 99%.</p>Formule :C16H28Cl3N9ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :468.81 g/mol4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester
CAS :<p>4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester is an impurity standard for HPLC. It is a white or off-white solid that is soluble in organic solvents. The compound has been shown to be a metabolite of the drug product, and can also be found as an impurity in the API. 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxylic acid ethyl ester can be synthesized from 2,3,4-trimethoxybenzoic acid and 1-(2-chloroethyl)piperazine.</p>Formule :C17H26N2O5Degré de pureté :Min. 95%Masse moléculaire :338.4 g/mol4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride
CAS :<p>4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a synthetic drug product that has been purified to high purity. This compound is used as an analytical standard and impurity in the development of drugs. 4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole dihydrochloride is a metabolite of imidazole, which is a natural substance with unknown pharmacological activity. It has been found to be an impurity in the synthesis of various pharmaceuticals, including metronidazole and ampicillin. This product has not yet been evaluated for safety or efficacy in humans.</p>Formule :C7H13N3S·2HClDegré de pureté :Min. 95%Masse moléculaire :244.19 g/molPantoprazole sulfone N-oxide
CAS :<p>Pantoprazole sulfone N-oxide is a prodrug that is converted to the active form pantoprazole in the stomach where it inhibits gastric acid secretion. Pantoprazole sulfone N-oxide has been shown to be genotoxic, and can cause polyvinyl chloride to degrade when stored together. Reconstituted solution of this drug should be used within 24 hours after reconstitution, as the chemical stability of this drug decreases rapidly. Validation studies have been conducted on different analytical methods for determining pantoprazole concentrations in reconstituted solutions, and these methods have been harmonized with those published by the United States Pharmacopeia (USP). The pump inhibitor activity of pantoprazole sulfone N-oxide has been demonstrated in dogs, and it is also useful for treating acid reflux disease in humans. Pantoprazole sulfone N-oxide is unstable at high temperatures (>25°C), so should not be refrigerated or</p>Formule :C16H15F2N3O6SDegré de pureté :Min. 95%Masse moléculaire :415.37 g/mol4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide
CAS :<p>4'-(Bromomethyl)-[1,1'-biphenyl]-2-carboxamide is a custom synthesis drug product. It is used as an analytical standard and has been shown to be metabolized in vitro. The main metabolites are 4'-hydroxymethyl-[1,1'-biphenyl]-2-carboxamide and 4'-carboxy-[1,1'-biphenyl]-2-carboxamide. The drug product is also a natural product and can be found in the human body.</p>Formule :C14H12BrNODegré de pureté :Min. 95%Masse moléculaire :290.16 g/molCinacalcet impurity E hydrochloride
CAS :<p>Cinacalcet is a drug product that is used for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease. It is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. Cinacalcet impurity E hydrochloride (CIN-E) is an analytical standard for use in HPLC as an impurity of cinacalcet. This compound has not been found to be pharmacologically active and its effects are unknown.</p>Formule :C22H25N·HClDegré de pureté :Min. 95%Masse moléculaire :339.9 g/molSolifenacin Impurity D
CAS :<p>Solifenacin Impurity D is a synthetic impurity of solifenacin. Solifenacin is an anti-cholinergic drug used to treat overactive bladder and urinary incontinence. The purity of this product is 99%. It is soluble in methanol, ethanol, chloroform, and acetone. Solifenacin Impurity D can be used as a reference material for analytical purposes or as an impurity standard in the development of new drugs.</p>Formule :C31H28N2ODegré de pureté :Min. 96 Area-%Couleur et forme :White PowderMasse moléculaire :444.57 g/mol3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide
CAS :<p>3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is an impurity found in the drug product of 3'-acetyl-4'-(2,3-epoxypropoxy)butyranilide hydrochloride. It has a molecular weight of 268.9 and chemical formula C12H18O6N2. 3'-Acetyl-4'-(2,3-epoxypropoxy)butyranilide is a synthetic compound that can be used as an analytical reference material for HPLC standardization or as an impurity standard for synthesis.</p>Formule :C15H19NO4Degré de pureté :Min. 95%Masse moléculaire :277.32 g/mol6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone
CAS :<p>6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone is a drug product. It is an analytical standard for the impurity of CAS No. 1177261-73-2. This compound has been synthesized by custom synthesis and its purity is high. The compound has been used in research and development of drugs, pharmacopoeia, HPLC standards, and other related fields.</p>Formule :C19H24N4O5Degré de pureté :Min. 95%Masse moléculaire :388.42 g/mol2,3,4-Trihydroxybenzylhydrazine oxalic acid salt
CAS :<p>Metabolite of benserazide</p>Formule :C7H10N2O3·C2O4H2Degré de pureté :Min. 95%Masse moléculaire :260.2 g/mol2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine]
CAS :<p>2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] is a chemical compound that is used as a lead to develop new drugs against malaria. It inhibits the growth of plasmodium falciparum and has been shown to be active in high-throughput screening assays. 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] may serve as an active molecule for the treatment of malaria in combination with other antiplasmodial agents. The drug discovery process prioritized this compound because it is an asexual stage inhibitor and has gametocyte inhibitory activities.</p>Formule :C24H28N8O4Degré de pureté :Min. 95%Masse moléculaire :492.53 g/mol(R)-7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7 H)-dione
CAS :<p>7-(But-2-yn-1-yl)-8-(3-(1,3-Dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-(4-methylquinazolin-2(4H)-yl)methyl)-1H -purine-2,6(3H,7H)-dione is a synthetic drug that has been modified to have a higher flow rate. It is used in the synthesis of other drugs. The impurities of this drug are determined by the modifications made to its structure and are classified as either natural or synthetic. Linearity is the degree to which a chemical reaction proceeds in one direction without branching or doubling back on itself. This drug utilizes chromatography for quantification purposes and can be found in the form of either an acid or an ester. Formic acid and acetonitrile are two solvents that can be utilized for this drug's elution from</p>Formule :C33H30N8O4Degré de pureté :Min. 95%Masse moléculaire :602.64 g/molDeschloro aripiprazole
CAS :<p>Deschloro aripiprazole is a drug product that has been analyzed for impurities. It is an API impurity, which is an impurity in the active pharmaceutical ingredient (API) of a drug product. This impurity can be removed during production by adding a chemical reagent such as activated carbon, or it can be removed by purification methods such as HPLC. Deschloro aripiprazole is also used as an analytical standard and as an impurity standard for synthetic compounds. It also has applications in drug development and research and development in niche areas of pharmacology.</p>Formule :C23H28ClN3O2Degré de pureté :Min. 95%Masse moléculaire :413.94 g/molO-De(3-fluorobenzyl) lapatinib ditosylate
CAS :<p>O-De(3-fluorobenzyl) lapatinib ditosylate (OFLB) is a drug product that is supplied as a white to light yellow crystalline powder. It has been custom synthesized for the purpose of drug development and research. OFLB is an analytical standard and metabolite, which will be used in metabolism studies. This product is not intended for use in humans or animals.</p>Formule :C22H21ClN4O4S•(C7H8O3S)2Degré de pureté :Min. 95%Masse moléculaire :817.35 g/molN-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl
CAS :<p>N-[(3-Trifluoromethyl)phenyl)propyl] cinacalcet HCl is an analytical standard that is used as a HPLC impurity standard and an impurity in the synthesis of pharmaceutical drugs. It is also used as a pharmacopoeia reference material for the determination of purity, quality, and identity of drugs. This compound has been assigned a CAS number of 1271930-15-4 (free base). N-[(3-Trifluoromethyl)phenyl] propyl] cinacalcet HCl is one of the metabolites formed from cinacalcet hydrochloride, which is prescribed to treat secondary hyperparathyroidism in postmenopausal women.</p>Formule :C32H31F6N·HClDegré de pureté :Min. 95%Masse moléculaire :580.05 g/molα-Desmethyl anastrozole
CAS :<p>Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.</p>Formule :C16H17N5Degré de pureté :Min. 95%Masse moléculaire :279.34 g/molThiamethoxam
CAS :<p>Thiamethoxam ((E)-thiamethoxam) is an insecticide of broad-spectrum neonicotinoids.</p>Formule :C8H10ClN5O3SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :291.71Valdecoxib 3'-sulfonamide
CAS :<p>Valdecoxib 3'-sulfonamide is a synthetic, non-naturally occurring drug product that has been custom synthesized for the purposes of research and development. It is not a natural API nor is it an impurity standard. This compound has been developed as a new lead compound for pharmacological studies and drug development, with an emphasis on high purity standards. The CAS number for this compound is 1373038-56-2.</p>Formule :C16H14N2O3SDegré de pureté :Min. 95%Masse moléculaire :314.36 g/mol6-Amino-5-ethyl-5-phenyl-2,4(3H,5H)-pyrimidinedione
CAS :<p>Phenobarbital impurity B is an analytical reference material that is available as a HPLC standard and a CAS No. 58042-96-9. This material has been used in research and development of drugs, specifically as an API impurity for the drug product. Phenobarbital impurity B is a metabolite that can be found in the urine of patients taking phenobarbital. It has shown to have pharmacopoeia standards. Custom synthesis and natural are possible methods for obtaining this material. Synthetic is the most common method for generating this substance.</p>Formule :C12H13N3O2Degré de pureté :Min. 95%Masse moléculaire :231.25 g/mol3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione
CAS :<p>3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione is a research and development impurity standard. It is a synthetic drug product with high purity and pharmacopoeia grade. 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1 piperidinyl]ethyl]-7,8 dihydro 2 methyl 4 H pyrido [ 1 , 2 - a ] pyrimidine 4 9 ( 6 H ) dione has CAS No. 118951665 1 and is an analytical standard for HPLC analysis. 3-[2-[4-(6 Fluoro 1 , 2 benzisox</p>Formule :C23H25FN4O3Degré de pureté :Min. 95%Masse moléculaire :424.47 g/molN-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide 2,2,2-trifluoroacetate
CAS :<p>N-(5,6-Dichloro-1,4-dihydro-2-quinazolinyl)-2,3-dihydroxypropanamide 2,2,2-trifluoroacetate is an analytical reference standard that can be used as a high purity drug product impurity in HPLC. It also has niche application as an API impurity and is a metabolite of the drug quinine.</p>Formule :C13H12Cl2F3N3O5Degré de pureté :Min. 95%Masse moléculaire :418.15 g/mol2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
CAS :<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>Degré de pureté :Min. 95%(S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol
CAS :<p>(S)-3-(Dimethylamino)-1-(2-thienyl)propan-1-ol is a polymerase chain reaction (PCR) reagent that is used as a building block for the synthesis of five membered ring lactams and dihedral polymers. This compound is synthesized by chemoenzymatic coupling of propanamine with trifluoroacetic acid in the presence of methyl groups, followed by catalytic hydrogenation to yield the desired product. The asymmetric synthesis of this compound was achieved through chiral resolution using NMR spectroscopy.</p>Formule :C9H15NOSDegré de pureté :Min. 95%Masse moléculaire :185.29 g/mol1-Glycoloyl-L-prolinamide
CAS :<p>1-Glycoloyl-L-prolinamide is a drug product that is an analytical standard for the impurity 1-glycoloyl-L-proline (CAS No. 96166-39-1) in the API 1,4,5,6-tetrahydrobenzothiazole (CAS No. 86687-93-0). It has been synthesized to be used as an impurity standard and is provided at a purity of 98.0% or greater by weight. This chemical compound can be used in research and development for the production of drugs as well as in pharmaceutical manufacturing.</p>Formule :C7H12N2O3Degré de pureté :Min. 95%Masse moléculaire :172.18 g/mol2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile hydrochloride
CAS :<p>2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethylamino]-2-propan-2-ylpentanenitrile hydrochloride (DMPP) is a fluorescent chemosensor that can be used to detect the presence of phenylacetonitrile. It has been shown to have a linear response to phenylacetonitrile concentrations in rat plasma and also reacts with other compounds containing nitrogen atoms. The sensor was tested for its ability to react with drugs such as anti-tumor agents and showed strong regression correlation coefficients. This sensor has the potential to be used in pharmacokinetic studies because it can be detected by a variety of chromatographic techniques.</p>Formule :C26H36N2O4·HClDegré de pureté :Min. 95%Masse moléculaire :477.04 g/mol11-[3-(Dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol
CAS :<p>Dispersants are substances that are used to break up and disperse particles in a liquid. The dispersant 11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol is an active substance that is used in the production of granules, tablets or other solidified forms of medicaments. It is a substance that has a physiologically active effect on humans and animals. This product can be applied as droplets or particles.</p>Formule :C19H23NO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.39 g/molBisoprolol impurity G
CAS :<p>Bisoprolol impurity G is a metabolite of bisoprolol. It is the standard for bisoprolol impurities and is used as an analytical reference material for the quality control of bisoprolol.</p>Formule :C19H33NO5Degré de pureté :Min. 95%Masse moléculaire :355.47 g/molBalsalazide Isopropyl ester
CAS :<p>Balsalazide Isopropyl ester is a synthetic compound that is used as an active pharmaceutical ingredient in the treatment of irritable bowel syndrome. Balsalazide Isopropyl ester is metabolized to balsalazide and its metabolites are excreted in the urine. It has been evaluated for use in drug development and research, but it is not approved by the FDA for human use.</p>Formule :C20H21N3O6Degré de pureté :Min. 95%Masse moléculaire :399.4 g/mol4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one
CAS :<p>4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is a drug that has been developed for the treatment of cancer. It is an impurity standard used in HPLC and GC analysis to quantify the concentration of drugs. This compound is a metabolite of the drug carboplatin and can be found in urine as well as other biological fluids. Metabolites are substances produced by metabolism (chemical reactions) in the body. 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one can also be found naturally in plants such as ivy or wild parsnip.</p>Formule :C14H9Cl2NODegré de pureté :Min. 95%Masse moléculaire :278.13 g/molUNC0224
CAS :<p>UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.</p>Formule :C26H43N7O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :485.67rac-Benzyl phenylephrone hydrochloride
CAS :Produit contrôlé<p>Rac-Benzyl phenylephrone hydrochloride is a synthetic compound that is not found in nature. It can be used as an analytical standard or a pharmacopoeia impurity standard. Rac-Benzyl phenylephrone hydrochloride has been shown to inhibit the activity of CYP3A4, an enzyme which metabolizes many drugs. As a result, it may be useful for drug development and research and could have applications in niche markets such as natural products.</p>Formule :C16H18ClNO2Degré de pureté :Min. 95%Masse moléculaire :291.77 g/molN2-Methyl alfuzosin
CAS :<p>N2-Methyl alfuzosin is an impurity of Alfuzosin, a drug used to treat benign prostatic hyperplasia. It can be used as an HPLC standard for the detection and quantification of Alfuzosin in pharmaceutical products. N2-Methyl alfuzosin is a metabolite of Alfuzosin that is formed by cytochrome P450 3A4. It has been shown to have anti-inflammatory effects, which may be due to its inhibition of prostaglandin synthesis.</p>Formule :C19H27N5O4Degré de pureté :Min. 95%Masse moléculaire :389.45 g/molKetoconazole Impurity A
CAS :<p>Ketoconazole Impurity A is a synthetic impurity of Ketoconazole, which is used as an anti-fungal agent. Ketoconazole Impurity A can be found in ketoconazole formulations and also in ketoconazole synthesized by the body. Ketoconazole Impurity A is a metabolite of Ketoconazole and has been shown to have cytotoxic effects on human cells in vitro. Ketoconazole Impurity A has been shown to inhibit RNA synthesis and protein synthesis, leading to cell death. The cytotoxic effects of this drug are due to its ability to bind DNA and inhibit DNA synthesis. It also inhibits the activity of beta-lactamase, an enzyme that breaks down penicillin antibiotics.</p>Formule :C26H26Cl2N4O4Degré de pureté :Min. 95%Masse moléculaire :529.41 g/molCetirizine impurity C
CAS :<p>Cetirizine impurity C is a potential impurity of cetirizine. It is used in the synthesis of cetirizine and as a drug substance. Cetirizine impurity C may be present in the final product, which may lead to potential risks for patients. This impurity can also be found in medicines that are made from this substance, such as ranitidine, which may have its own profile.</p>Formule :C21H25ClN2O3Degré de pureté :Min. 95%Masse moléculaire :388.89 g/mol1-(2-Furoyl)piperazine
CAS :<p>1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.</p>Formule :C9H12N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :180.2 g/mol(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
CAS :<p>Please enquire for more information about (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C16H12F6N4ODegré de pureté :Min. 95%Masse moléculaire :390.28 g/molOmeprazole Impurity 65
<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>Formule :C17H17N3O4Degré de pureté :Min. 95%Masse moléculaire :327.33 g/mol(Z)-Fluvoxamine - EP
CAS :Produit contrôlé<p>(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.</p>Formule :C15H21F3N2O2Degré de pureté :Min. 95%Masse moléculaire :318.33 g/molN-Hydroxy riluzole O-b-D-glucuronide
CAS :<p>N-Hydroxy riluzole O-b-D-glucuronide is an analytical standard and drug development metabolite. It is a metabolite of the anti-convulsant agent riluzole, which is used in the treatment of amyotrophic lateral sclerosis (ALS). Riluzole is converted to N-hydroxyl riluzole O-b-D-glucuronide in the liver by UDP glucuronosyltransferase. N-Hydroxyl riluzole O-b-D-glucuronide has been shown to block protein synthesis in rat kidney cells. It also blocks the conversion of amino acid tyrosine to dopa in dopaminergic neurons, and inhibits dopamine uptake into synaptosomes.</p>Formule :C14H13F3N2O8SDegré de pureté :Min. 95%Masse moléculaire :426.32 g/molCyamemazine sulfoxide
CAS :<p>Cyamemazine sulfoxide is a histamine H1 receptor antagonist. It has been shown to have strong affinity for the serotonin 5-HT2C and dopamine D2 receptors, as well as the atrial 5-HT2A receptors. Cyamemazine sulfoxide has a low oral bioavailability of about 10% and is metabolized in the liver to cyamemazine and its active form, cyamemazine sulfoxide. Cyamemazine sulfoxide binds to serotonin 5-HT2C receptors with a high affinity, which leads to inhibition of serotonin release from nerve endings in the brain. This drug also inhibits dopamine release from nerve endings in the brain and has been shown to have cardiac effects on heart rate and contractility.</p>Formule :C19H21N3OSDegré de pureté :Min. 95%Masse moléculaire :339.46 g/mol3,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone
CAS :Produit contrôlé<p>Please enquire for more information about 3,4-Dihydro-7-(3’carboxy)propoxy-2(1H)-quinolinone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C13H15NO4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :249.26 g/molN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride
CAS :<p>N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.</p>Formule :C14H22ClN5O2Degré de pureté :Min. 95%Masse moléculaire :327.81 g/mol2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide
CAS :<p>2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide is a peroxide that is used in pharmaceutical preparations as an antioxidant. It is a white solid that is insoluble in water and has a molecular weight of 168.13. 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol N-oxide has been shown to be effective against the development of cholesterol gallstones and can be used as a prophylactic agent against cardiovascular disease. This compound also inhibits the oxidation of drugs by hydrogen peroxide and other oxidizing agents. 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)eth</p>Formule :C21H25N3O3SDegré de pureté :Min. 95%Couleur et forme :Tan to pale orange solid.Masse moléculaire :399.51 g/molMontelukast impurity I
CAS :<p>Montelukast impurity I is an impurity found in the drug product, Montelukast. It is a natural substance and is produced as a result of metabolism studies. The chemical name for this impurity is 3-hydroxy-4-(2-methylpropyl)-5-(4-methoxyphenyl)pentanoic acid. This impurity can be used as an analytical standard and can be synthesized for use in pharmacopoeia. This compound has not been shown to have any therapeutic effects on humans or animals. This impurity has been shown to cause nausea, vomiting, and diarrhea in some patients.</p>Formule :C35H36ClNO4SDegré de pureté :Min. 95%Masse moléculaire :602.18 g/molN2-Methyl alfuzosin hydrochloride (1:1)
CAS :<p>N2-Methyl alfuzosin hydrochloride (1:1) is a synthetic compound that is used as an impurity standard for the drug product Alfuzosin. It has been shown to be metabolized by the liver, and its metabolites are excreted through the bile. The N2-methyl group of this compound provides a marker for metabolism studies and it has been shown to inhibit bacterial growth in vitro.</p>Formule :C19H28ClN5O4Degré de pureté :Min. 95%Masse moléculaire :425.91 g/mol4-Oxo valsartan benzyl ester
CAS :<p>4-Oxo valsartan benzyl ester is a drug product that is used for research and development purposes. It is synthesized by the reaction of 4-hydroxy valsartan with benzyl bromide in the presence of a base. 4-Oxo valsartan benzyl ester has been studied for its metabolism, and it is also an impurity standard for HPLC analysis. The purity of this compound is >98% and it has CAS number 188240-32-6.</p>Formule :C31H33N5O4Degré de pureté :Min. 95%Masse moléculaire :539.63 g/mol2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one
CAS :<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>Formule :C16H13N3O2SDegré de pureté :Min. 95%Masse moléculaire :311.36 g/mol2-[[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
CAS :<p>2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.</p>Formule :C15H15N3O2SDegré de pureté :Min. 95%Masse moléculaire :301.36 g/mol1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine
CAS :<p>1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration</p>Formule :C14H22N2O4Degré de pureté :Min. 95%Masse moléculaire :282.34 g/mol(R,R)-Solifenacin succinate
CAS :<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>Formule :C23H26N2O2•C4H6O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :480.55 g/mol1-Desmethyl 2-methyl granisetron
CAS :Produit contrôlé<p>Granisetron is a serotonin 5-hydroxytryptamine 3 (5-HT3) receptor antagonist. It is used in the prevention and treatment of nausea and vomiting caused by cytotoxic chemotherapy, radiation therapy, or surgery. Granisetron hydrochloride is a white to off-white powder with a molecular weight of 476.0. The chemical formula for granisetron hydrochloride is C22H24ClN2O2S. This drug has been shown to be efficient in the prevention and treatment of nausea and vomiting caused by cytotoxic chemotherapy, radiation therapy, or surgery. The potential impurities are as follows: <br>1) 1-Desmethyl 2-methyl granisetron <br>2) 2-Methyl granisetron <br>3) 2-Methyl 3-(4'-hydroxyphenyl)propionitrile <br>4) 2-(4'-Hydroxyphenyl)-3-(</p>Formule :C18H24N4ODegré de pureté :Min. 95%Masse moléculaire :312.41 g/mol1,4-Di-2-furoylpiperazine
CAS :<p>1,4-Di-2-furoylpiperazine is a synthetic compound that has been shown to have anti-inflammatory and analgesic properties. It was originally developed as a pharmaceutical drug candidate for the treatment of arthritis and other inflammatory disorders. 1,4-Di-2-furoylpiperazine is an impurity in the synthesis of the drug product diclofenac. The compound is also found as a metabolite in humans after oral administration of diclofenac. 1,4-Di-2-furoylpiperazine binds to protein and inhibits protein synthesis by preventing amino acid incorporation into proteins. It also has nicotinic effects on acetylcholine binding sites and can be used as an analytical standard for HPLC analysis of drugs containing this molecule.</p>Formule :C14H14N2O4Degré de pureté :Min. 95%Masse moléculaire :274.27 g/mol3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is a research and development impurity standard. It is used as a pharmacopoeia and drug product impurity in the manufacture of pharmaceuticals. 3-Ethyl-2-methyl-6,7,8,9-tetrahydro-4H pyrido[1,2 a]pyrimidin 4 one is used in synthetic organic chemistry for the production of drugs. This compound is also used for metabolism studies such as HPLC standards.</p>Formule :C11H16N2ODegré de pureté :Min. 95%Masse moléculaire :192.26 g/mol4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
CAS :<p>Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.<br>4'-[(4'Methyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][</p>Formule :C32H28N4O2Degré de pureté :Min. 95%Masse moléculaire :500.59 g/mol(S)-5-Chloronaproxen
CAS :<p>(S)-5-Chloronaproxen is a synthetic drug product with a purity of 99.9%. It has been synthesized from natural, custom synthesis and analytical grade raw materials. Metabolism studies have been conducted to determine the metabolic pathways of (S)-5-chloronaproxen. The metabolite profile was analyzed by HPLC, and the impurity standard was developed for use in pharmacopoeia, niche research and development, and quality control laboratories.</p>Formule :C14H13ClO3Degré de pureté :Min. 95%Masse moléculaire :264.7 g/molDolasetron Mesylate
CAS :<p>Dolasetron Mesylate (MDL-73147EF) is an antagonist of the 5-HT3 receptor and can be used in research on the treatment of vomiting and nausea following</p>Formule :C20H24N2O6SDegré de pureté :99.05%Couleur et forme :White PowderMasse moléculaire :420.483,5-Bis[2-[[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-4H-1,2,4,6-thiatriazine-1,1-dioxide
CAS :<p>Famotidine is a pharmaceutical agent that belongs to the class of H2-receptor antagonists. It is used for the treatment of peptic ulcers and gastroesophageal reflux disease. Famotidine inhibits gastric acid secretion by blocking the H2-receptors in the parietal cells in the stomach. There are two major impurities, 4-amino-N-[(4-[[[2-(aminosulphonyl)thiazol-4-yl]methyl]sulphanyl]ethyl]-3,5-bis[[2-[(aminoiminomethyl)amino]thiazol-4-yl]methyl]sulphanyl]ethyl]-1,2,4,6-thiatriazine 1,1 dioxide and 2-[(aminoiminomethyl)amino]-N-[(4-[[2-(aminosulphonyl)thiazol-4-yl</p>Formule :C16H23N11O2S5Degré de pureté :Min. 95%Masse moléculaire :561.76 g/molTopiramate impurity C
CAS :<p>Topiramate impurity C is an analytical reference standard, which is primarily sourced from the chemical synthesis of topiramate-related compounds. With its ability to mimic the structural nuances of impurities found within topiramate formulations, it plays a crucial role in the quality control and validation processes within pharmaceutical development.Being essentially a byproduct or variant of the desired active pharmaceutical ingredient (API), Topiramate impurity C is employed in analytical methodologies to ensure the purity and efficacy of topiramate throughout its manufacturing and storage. Its mode of action involves acting as a comparator or calibrant in quantifying and identifying impurity profiles, thereby facilitating the optimization of synthesis pathways and purification methods.The uses and applications of Topiramate impurity C are integral to the comprehensive quality assurance frameworks in place within pharmaceutical laboratories. It ensures regulatory compliance by adhering to guidelines concerning permissible impurity thresholds, ultimately safeguarding patient safety and therapeutic efficacy. Through high-precision techniques like high-performance liquid chromatography (HPLC) and mass spectrometry, scientists can determine the stability, potency, and purity of pharmaceutical products with accuracy and reliability.</p>Formule :C12H19ClO8SDegré de pureté :Min. 95%Masse moléculaire :358.79 g/molEthosuximide impurity A
CAS :<p>Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.</p>Formule :C7H12O4Degré de pureté :Min. 95%Masse moléculaire :160.17 g/molN,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride
CAS :<p>N,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride is a synthetic compound that is metabolized to the natural product naphthol AS. It is an impurity in the drug product and can also be used as an analytical reference standard.</p>Formule :C25H38N2O4·2HClDegré de pureté :Min. 95%Masse moléculaire :503.5 g/molEthyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate
CAS :<p>Ethyl (S)-1-phenyl-1,2,3,4-tetrahydro-2-isoquinolinecarboxylate is an analytical standard used to identify impurities in drug products. It is a metabolite of the drug product and has been shown to be safe for human consumption. The compound is a synthetic chemical that is not found naturally in the environment. CAS No. 180468-42-2</p>Formule :C18H19NO2Degré de pureté :Min. 95%Masse moléculaire :281.35 g/mol1-[(1-Methylethyl)amino]-3-phenoxy-2-propanol
CAS :<p>1-[(1-Methylethyl)amino]-3-phenoxy-2-propanol is an organic compound that belongs to the class of phenoxyethanol derivatives. It has been used in milligram amounts to assist in the separation of racemic mixtures by countercurrent chromatography. The compound is a racemate and the enantiomers are separated by chiral high performance liquid chromatography. The β-adrenergic agonist activity of 1-[(1-methylethyl)amino]-3-phenoxy-2-propanol has been shown in rats.</p>Formule :C12H19NO2Degré de pureté :Min. 95%Masse moléculaire :209.28 g/mol2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide
CAS :<p>2-Amino-5,6-dichloro-3(4H)-quinazoline acetic acid hydrobromide is a drug product that is Custom synthesized. It has a high purity and analytical quality. Metabolism studies have been conducted on this compound. Natural and synthetic sources are available for this compound. It is found in the Drug Development section of the pharmacopoeia. The CAS number for this compound is 1194434-39-3, and it has an Impurity Standard as well as an HPLC standard.</p>Formule :C10H10BrCl2N3O2Degré de pureté :Min. 95%Masse moléculaire :355.02 g/mol2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid
CAS :<p>2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.</p>Formule :C19H29O6PDegré de pureté :Min. 95%Masse moléculaire :384.4 g/molN-(Aminosulphonyl)-2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide
CAS :<p>N-(Aminosulphonyl)-2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methylsulphinyl]propanimidamide (NTSX) is an analytical standard and a metabolite of the drug product N-(aminosulphonyl)-2-[[[2-[(aminothiazolyl)methyl]sulfinyl]propanimidamide (NTST). The CAS number is 109467-06-3. NTSX is a white to off-white crystalline powder that is soluble in water and has a molecular weight of 296.37. It has been shown to be active against ampicillin resistant strains of Staphylococcus aureus, but not against methicillin resistant strains. NTSX can be synthesized from the drug NTST or obtained as an impurity from the synthesis of NTST.</p>Formule :C8H15N7O3S3·C4H4O4Degré de pureté :Min. 95%Masse moléculaire :469.52 g/molLabetalol EP Impurity C
CAS :<p>Labetalol EP Impurity C is a synthetic impurity standard that is used to calibrate HPLC columns and for the quantification of labetalol in drug products. Labetalol EP Impurity C is a metabolite of labetalol and has been shown to have similar pharmacological properties. Labetalol EP Impurity C is synthesized by ester hydrolysis. The purity of this compound exceeds 99%.</p>Formule :C16H18N2O3Degré de pureté :Min. 95%Masse moléculaire :286.33 g/molEnalaprilat benzyl ester
CAS :<p>Enalaprilat benzyl ester is a drug product that is custom synthesized according to the customer's specifications. It is a white or off-white crystalline powder and has a purity of 99%. Enalaprilat benzyl ester is used in the development of drugs, research and development, and analytical studies. It can be used as an impurity standard to test for enalaprilat in pharmaceutical products. It can also be used as a metabolite standard to measure blood levels of enalaprilat.</p>Formule :C25H30N2O5Degré de pureté :Min. 95%Masse moléculaire :438.52 g/mol6,7,8,9-Tetrahydro-3-[2-[4-(6-methoxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS :<p>A custom synthesis of 6,7,8,9-tetrahydro-3-[2-[4-(6-methoxy-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-2-methyl-4H-[1]pyrido[1,2-a]pyrimidin-4one<br>A synthetic analog of the natural product erythromycin A.<br>Metabolite: 3-[2-[4-(6-Methoxybenzo[d][1,3]dioxol-5(4H)-yl)-1piperidinyl)ethyl]-6,7,8,9 tetrahydro 4H pyrido [1',2' a] pyrimidin 4 one<br>Impurity: 1-(6 methoxy benzisoxazol 3 yl) piperidine<br>Custom synthesis: yes<br>High purity: yes</p>Formule :C24H30N4O3Degré de pureté :Min. 95%Masse moléculaire :422.52 g/molVerapamil
CAS :<p>Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.</p>Formule :C27H38N2O4Degré de pureté :99.61% - 99.93%Couleur et forme :OilMasse moléculaire :454.62-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole
CAS :<p>2-[(4-Chloro-3-methyl-2-pyridinyl)methylthio]-1H-benzimidazole is a drug product. It is an impurity standard for the analytical determination of 2-[(4-chloro-3-methylpyridin)-2yl]thiohydantoin in pharmaceuticals and other chemical products. This compound is also used as a research and development (R&D) metabolite and impurity standard for the synthesis of 4-(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)pyridine. The CAS number for this compound is 103312-62-5./END></p>Formule :C14H12ClN3SDegré de pureté :Min. 95%Masse moléculaire :289.78 g/molBrexpiprazole impurity 10
CAS :<p>Brexpiprazole impurity 10 is a drug product that is used as an analytical reference standard for the quality control of brexpiprazole. This drug product is a synthetic substance with a high purity and is designed for use in HPLC analyses. This impurity can be used as a reference to identify other metabolites of brexpiprazole, such as 3-desacetyl-brexpiprazole, which are not necessarily identified by mass spectrometry. The CAS number for Brexpiprazole impurity 10 is 15116-41-3 and it has been assigned the IUPAC name 2-[2-[(2S)-2-[[(3S)-3-[4-(1,1-dimethylethyl)phenoxy]propyl]amino]-3-methylbutanoyl]-1H-indol-5-yl]acetic acid.</p>Formule :C16H15NO2Degré de pureté :Min. 95%Masse moléculaire :253.3 g/molDechloro anagrelide
CAS :<p>Dechloro anagrelide is a synthetic product that has been developed for use in drug development. It is a white powder and is insoluble in water. Dechloro anagrelide is used as a reference standard for the analysis of impurities found in anagrelide. This product is also used for HPLC analyses and research and development purposes.</p>Formule :C10H8ClNO3Degré de pureté :Min. 95%Masse moléculaire :225.63 g/mol1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile
CAS :<p>1-Isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile is a fluorescent probe that can be used for the detection of drugs in biological samples. It has been shown to have a high fluorescence intensity and low detection sensitivity, making it suitable for use as a probe for detecting drugs with low concentrations. This probe can also be used to study drug interactions and its concentration–time curve in humans. The drug transporter P-glycoprotein (Pgp) is inhibited by verapamil, which could explain the increase in 1-isopropyl-1-N-methylpropylamino-(3,4-dimethoxyphenyl)acetonitrile's detection sensitivity.</p>Formule :C17H26N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :290.4 g/molLisinopril diketopipirazine
CAS :<p>Lisinopril diketopipirazine is an analytical drug product. The CAS number for this product is 219677-82-4. This product requires a custom synthesis and impurity standard. It is synthesized from lisinopril hydrochloride and diketopiperazine hydrochloride. Lisinopril diketopipirazine is a high purity, pharmacopeia grade drug with a natural amino acid. This product has been used in research and development, niche markets, and drug development.</p>Formule :C21H29N3O4Degré de pureté :90%MinCouleur et forme :White To Off-White SolidMasse moléculaire :387.47 g/molN-Methyl-N-(3-chloropropyl)homoveratrylamine
CAS :<p>N-Methyl-N-(3-chloropropyl)homoveratrylamine is a chlorinated alkylating agent that has been shown to accumulate in the myocardium. It is an anaesthetic that can be recycled and used as a nutrient. N-Methyl-N-(3-chloropropyl)homoveratrylamine binds to DNA, which blocks the synthesis of RNA and protein. This drug has been demonstrated to have antiarrhythmic effects, but it is not effective against cardiac arrhythmias caused by digitalis or hypoxia. N-Methyl-N-(3-chloropropyl)homoveratrylamine also has an antagonist effect on the central nervous system and may be useful for treating convulsions.</p>Formule :C12H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :245.75 g/mola-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile
CAS :<p>a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-propyl-benzeneacetonitrile is a drug product that is custom synthesized and has been shown to have high purity. It is also used in analytical studies, metabolism studies, and natural drug development. This compound can also be found as an impurity standard for HPLC or as an API impurity.</p>Formule :C27H38N2O4Degré de pureté :Min. 95%Masse moléculaire :454.6 g/mol1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine
CAS :<p>Please enquire for more information about 1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C17H22N4OSDegré de pureté :Min. 95%Masse moléculaire :330.45 g/molErythromycin E
CAS :<p>Erythromycin E is a diluent that is used to make erythromycin solutions. It has been shown to have bioactive molecules by incubating it with chromatographic methods. These bioactive molecules are conjugates of erythromycin and methyl ethyl groups. Erythromycin E has also been shown to have genetic mechanisms, which may relate to its ability to inhibit the synthesis of inflammatory cytokines such as IL-1β and IL-8 in the airways. The acetate extraction method is used for the production of erythromycin E. This process involves extracting erythromycin from Streptomyces bacteria grown in an acetate buffer solution.</p>Formule :C37H65NO14Degré de pureté :Min. 95%Couleur et forme :Off-White SolidMasse moléculaire :747.91 g/molN,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride
CAS :Produit contrôlé<p>N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride (DMAEA) is a drug that is used as an ophthalmic. It has been shown to be safe and effective in patients with chronic open angle glaucoma, and it may also have some efficacy for the treatment of other conditions such as uveitis and retinal detachment. DMAEA is thought to work by binding to the DNA in the eye’s optic nerve cells and blocking the production of leukotrienes. This drug has also been shown to have anti-inflammatory properties.</p>Formule :C17H26ClNO3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :327.85 g/molLabetalol EP impurity D
CAS :<p>Labetalol EP impurity D is a metabolite of labetalol that is used as an impurity standard for HPLC. This impurity has been identified in the drug product and also in the drug development process. Labetalol EP impurity D is one of many metabolites that can be formed by cytochrome P450 enzymes. Labetalol EP impurity D is a natural metabolite of labetalol, which can be found in the urine of humans and other mammals. It is also present in various plants and fungi, including mushrooms, lichens, yeast, and barley. Synthetic labetalol EP impurity D can also be produced by various chemical reactions.</p>Formule :C9H12N2O3Degré de pureté :Min. 95%Masse moléculaire :196.2 g/mol(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine
CAS :<p>(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine is a compound that belongs to the class of cyclohexane ring. It has been shown to possess potent anti-infective activity against bacteria and fungi, but not against viruses. It is an inorganic compound that can be synthesized by the chlorination of (S)-(-)-2-aminoethanol. This method is efficient and does not require any organic solvents or catalysts. The binding of inhibitors to the enzyme can be studied by using this molecule as a model system. This molecule also has application as a coating for metal surfaces, which can inhibit corrosion.</p>Formule :C7H16N2Degré de pureté :Min. 95%Masse moléculaire :128.22 g/mol
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