Stéroïdes et Dérivés
Les stéroïdes sont des composés organiques possédant une structure de quatre cycles fusionnés, connue sous le nom de noyau stéroïdien. Ce noyau peut être associé à divers groupes fonctionnels modifiant leurs propriétés et leurs fonctions biologiques. Les stéroïdes jouent un rôle clé dans la régulation des processus métaboliques et hormonaux. Ils sont utilisés en médecine pour traiter les troubles inflammatoires, les maladies auto-immunes et les déséquilibres hormonaux. De plus, certains dérivés stéroïdiens possèdent de puissantes propriétés anti-inflammatoires, comme les corticostéroïdes. Dans certaines thérapies spécifiques, ils sont utilisés pour réduire l’inflammation et soulager la douleur dans diverses maladies.
Chez CymitQuimica, nous proposons une variété de stéroïdes et de leurs dérivés pour la recherche et le développement pharmaceutique.
4949 produits trouvés pour "Stéroïdes et Dérivés"
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Tetrahydrodehydrocorticosterone
CAS :Produit contrôlé<p>Applications Tetrahydrodehydrocorticosterone inhibits aldosteronogenesis by intact cells at concentrations that inhibited angiotensin binding.<br>References Campanile, C.P., Goodfriend, T.L.: Steroids, 37, 681(1981)<br></p>Formule :C21H32O4Couleur et forme :NeatMasse moléculaire :348.482-Hydroxy Estrone
CAS :Produit contrôléFormule :C18H22O3Couleur et forme :Off-White To Light BrownMasse moléculaire :286.37Ethynyl Estradiol-2,4,16,16-d4
CAS :Produit contrôlé<p>Applications Isotope labelled Ethynyl Estradiol (E685100), an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.<br></p>Formule :C202H4H20O2Couleur et forme :White To Light YellowMasse moléculaire :300.4311-Deoxy Corticosterone-d7
CAS :Produit contrôlé<p>Applications Labelled Deoxycorticosterone. A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).<br>References Bohl, C., et al.: J. Med.Chem., 47, 3765 (2004), Smith, J., et al.: Steroids, 73, 1160 (2008),<br></p>Formule :C21H23D7O3Couleur et forme :White To Off-WhiteMasse moléculaire :337.5Ref: 10-F794924
5gÀ demander10gÀ demander25gÀ demander100gÀ demander250gÀ demander500gÀ demander100mgÀ demanderBetamethasone 17-Butyrate
CAS :Produit contrôlé<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Formule :C26H35FO6Couleur et forme :NeatMasse moléculaire :462.55(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione
CAS :Formule :C23H30O5Couleur et forme :ColourlessMasse moléculaire :386.48Alphadolone
CAS :Produit contrôlé<p>Applications Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.<br>References Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987), Serrao, J., et al.: Anesthesiology, 70, 780 (1989), Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),<br></p>Formule :C21H32O4Couleur et forme :NeatMasse moléculaire :348.48(6a,11b,16a)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione
CAS :Produit contrôlé<p>Applications (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione is an impurity of Fluocinolone Acetonide, Glucocorticoid; anti-inflammatory.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formule :C23H28F2O7Couleur et forme :NeatMasse moléculaire :454.466α-Methyl Hydrocortisone
CAS :<p>Applications A metabolite of Cortisone (C696500).<br>References Mashkovskii, M., et al.: Med. Agents, 2, 34 (2002),<br></p>Formule :C22H32O5Couleur et forme :Off-White To BeigeMasse moléculaire :376.499α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS :<p>Impurity Clobetasol Propionate EP Impurity J<br>Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Formule :C25H30ClFO4Couleur et forme :NeatMasse moléculaire :448.95Desmosterol
CAS :<p>Applications A metabolite of Cholesterol (C432501).<br>References Marx, J., et al.: Science, 294, 508 (2001), Plosch, T., et al.: J. Biol. Chem., 277, 33870 (2002), Lund, E., et al.: J .Biol. Chem., 278, 22980 (2003),<br></p>Formule :C27H44OCouleur et forme :White To Off-WhiteMasse moléculaire :384.6417-Deoxy Cortienic Acid
CAS :<p>Applications 17-Deoxy Cortienic Acid was used in the synthetic preparation of macrolactonolides, a class of potential antiinflammatory drugs.<br>References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013); Little, R.J., et al.: Pharma. Res., 16, 961 (1999); Manz. B., et al.: J. Steroid. Biochem., 17, 335 (1982);<br></p>Formule :C20H28O4Couleur et forme :NeatMasse moléculaire :332.437b-Fulvestrant
CAS :Produit contrôlé<p>Impurity Fulvestrant EP Impurity A<br>Applications Fulvestrant (F862500) impurity A. The S-isomer of Fulvestrant.<br>References Sharman, G.J., et al.: Mag. Resonance Chem., 39, 549 (2001),<br></p>Formule :C32H47F5O3SCouleur et forme :Light Brown SolidMasse moléculaire :606.7721-Deacetoxy Deflazacort
CAS :Produit contrôlé<p>Applications An intermediate of Deflazacort (D228975), a systematic corticosteroid.<br>References Nathansohn, G. et al.: Steroids, 13, 365 (1969); Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980),<br></p>Formule :C23H29NO4Couleur et forme :NeatMasse moléculaire :383.4817β-Estradiol 3-O-Sulfate Sodium
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 17β-Estradiol 3-O-Sulfate is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.<br>References Li, W.J., et al.: J. Pharmacol. Exp. Therp., 323, 236 (2007); Schneider, C., et al.: Steroids., 69, 245 (2004);<br></p>Formule :C18H23O5S·NaCouleur et forme :NeatMasse moléculaire :374.43Equilenin
CAS :<p>Applications Equilenin is a naturally occuring estrogenic steroidal hormone (1,2) isolated from urine of pregnant mares (3). Not found in human urine. Component of conjugated estrogenic hormones. Estrogen. This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Corbellini, A. et L.: Farmaco Sci. 1964 Nov;19:913-22.2. Stein, R. et al.: Tetrahedron 1970 Apr;26(8):1917-33.3. Nett, T. et al.: J. Reprod. Fertil. Suppl. 1975 Oct;(23):457-62.<br></p>Formule :C18H18O2Couleur et forme :Light Beige To Light YellowMasse moléculaire :266.334-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS :Produit contrôlé<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Formule :C23H26O3Couleur et forme :NeatMasse moléculaire :350.45Pregnenolone-d4
CAS :Produit contrôlé<p>Applications Pregnenolone-d4, is the labeled analogue of the Pregnenolone (P712200), which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>Formule :C212H4H28O2Couleur et forme :Off-WhiteMasse moléculaire :320.50∆6-Testosterone
CAS :Produit contrôlé<p>Impurity Testosterone Decanoate EP Impurity I<br>Applications A metabolite of Testosterone (T155000). Controlled substance.<br>References Peng, S., et al.: Steroids, 67, 39 (2002), Pozo, O., et al.: Drug Metab. Dispos., 37, 2153 (2009),<br></p>Formule :C19H26O2Couleur et forme :Beige To Light BrownMasse moléculaire :286.40Zilpaterol
CAS :Produit contrôlé<p>Stability Temperature Sensitive<br>Applications Zilpaterol is a β-Adrenergic agonist. Growth promotant.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004)<br></p>Formule :C14H19N3O2Couleur et forme :White To YellowMasse moléculaire :261.32N,O-Bis(trimethylsilyl)trifluoroacetamide (~90%)
CAS :Produit contrôlé<p>Applications Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Driscoll, J.S. et al.: J. Med. Chem., 34, 3280 (1991); Pan, L. et al.: J. Pharm. Biomed. Anal., 52, 589 (2010);<br></p>Formule :C8H18F3NOSi2Degré de pureté :~90%Couleur et forme :Colourless To Light YellowMasse moléculaire :257.40Estradiol 17-Propionate
CAS :Produit contrôlé<p>Applications A 17β-estradiol ester as prodrug of Estradiol (E888000).<br>References Kabasakalian, P., et al.: J. Pharm. Sci., 55, 642 (1966), Marsh, M., et al.: Br. Med. Bull., 48, 426 (1992),<br></p>Formule :C21H28O3Couleur et forme :White To Off-WhiteMasse moléculaire :328.45Altrenogest
CAS :Produit contrôlé<p>Applications A synthetic progestational agent used in veterinary medicine for the control of estrus in mares.<br>References Machnik M. et al.: J. Vet. Phamacol. Therap., 30, 86 (2007); Goncalves dos Santos, J.M. et al.: Anim. Reprod. Sci., 84, 407 (2004);<br></p>Formule :C21H26O2Couleur et forme :Light YellowMasse moléculaire :310.4317β-Dihydro Equilenin
CAS :<p>Applications The 17β-metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formule :C18H20O2Couleur et forme :NeatMasse moléculaire :268.354-Pregnen-17α,20β-diol-3-one
CAS :<p>Stability Store in Freezer<br>Applications 4-Pregnen-17α,20β-diol-3-one (cas# 1662-06-2) is a compound useful in organic synthesis.<br></p>Formule :C21H32O3Couleur et forme :White To Light YellowMasse moléculaire :332.48Methoxygonadiene (>90%)
CAS :Produit contrôlé<p>Applications Max LMG is a progestin derived steroid and not a 17-alpha alkylated steroid. Max LMG is structurally related to RU-486 and acts as an antiprogesterone, decreasing estrogen-like effects.<br>References Eenoo, P.V., et al.: J. Steroid. Biochem. Molec. Biol., 101, 161 (2006); Kafrouni, M. I., Clinical. Gastroenterol. Hepatol., 5, 805 (2007); Ponsoid, K., et al.: Pharmazie., 33, 729 (1978);<br></p>Formule :C20H28O2Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :300.44Dihydro Finasteride
CAS :<p>Impurity Finasteride EP Impurity A<br>Applications Dihydro Finasteride (Finasteride EP Impurity A) is the reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5α-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process.<br>References Bull, H.G. et al.: Am. J. Chem. Soc., 118, 2359 (1996); Liang, T. et al.: Endocrinol., 117, 571 (1985); Ellsworth, K.P. et al.: J. Steroid Bioche. Mol. Biol., 66, 271 (1998);<br></p>Formule :C23H38N2O2Couleur et forme :Off-WhiteMasse moléculaire :374.56δ4-Pregnen-20α-ol-3-one
CAS :Produit contrôlé<p>Impurity Progesterone EP Impurity B<br>Applications Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.<br>References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);<br></p>Formule :C21H32O2Couleur et forme :Off White SolidMasse moléculaire :316.486β-Hydroxycortisone
CAS :<p>Applications 6β-Hydroxycortisone can be used as a probe to detect inhibition of CYP3A4 in vivo.<br>References Peng, C.C., et. al.: Clin. Pharmacol. Ther., 89, 888 (2011)<br></p>Formule :C21H28O6Couleur et forme :NeatMasse moléculaire :376.442-Bromo 17β-Estradiol
CAS :<p>Stability Light Sensitive<br>Applications 17β-Estradiol (E888000) metabolite. An inhibitor of androstenedione aromatization, which is responsible for the conversion of androgens to estrogens. Agonistic ligands for the estrogen receptor in MCF-7 breast cancer cells.<br>References Numazawa, M. et al.: J. Steroid. Biochem. Mol. Biol., 96, 51 (2005); Vollmer, G. et al.: J. Seroid. Biochem. Mol. Biol., 39, 359 (1991); Brueggemeier, R. et al.: J. Steroid. Biochem., 21, 709 (1984)<br></p>Formule :C18H23BrO2Couleur et forme :NeatMasse moléculaire :351.281,2-Dihydro Exemestane
CAS :Produit contrôlé<p>Impurity USP Exemestane Related Compound A<br>Applications 1,2-Dihydro Exemestane is a related compound of Exemestane (E957000).<br>References Johannessen, D., et al.: Clin. Cancer Res., 3, 1101 (1997), Kaufmann, M., et al.: J. Clin. Oncol., 18, 1399 (2000), Coombes, R., et al.: Lancet, 369, 559 (2007),<br></p>Formule :C20H26O2Couleur et forme :NeatMasse moléculaire :298.4210β-Peroxy ∆4-Tibolone
CAS :Produit contrôlé<p>Applications ∆4-Tibolone derivative. A potential impurity of ∆4-Tibolone (T437505).<br>References Grunwell, J.F., et al.: Steroids, 27, 759 (1976),<br></p>Formule :C21H28O4Couleur et forme :NeatMasse moléculaire :344.44E,E-Dienestrol
CAS :Produit contrôlé<p>Applications A metabolite of Diethylstilbestrol.<br>References Liehr, J.G., et al.: Steroids, 40, 713 (1982),<br></p>Formule :C18H18O2Couleur et forme :NeatMasse moléculaire :266.33Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS :Produit contrôlé<p>Impurity Dutateride EP Impurity C<br>Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.<br>References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);<br></p>Formule :C21H31NO3Couleur et forme :White To Off-WhiteMasse moléculaire :345.48Limaprost
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formule :C22H36O5Couleur et forme :NeatMasse moléculaire :380.5217α-Dihydro Equilin
CAS :Produit contrôlé<p>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Formule :C18H22O2Couleur et forme :NeatMasse moléculaire :270.372-Hydroxy Atorvastatin Dihydrate Monosodium Salt
CAS :<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formule :C33H38FN2NaO8Couleur et forme :NeatMasse moléculaire :632.654-Methyl Estradiol
CAS :Produit contrôlé<p>Impurity Estradiol EP Impurity C<br>Applications 4-Methyl Estradiol (Estradiol EP Impurity C) is an impurity of Estradiol (E888000).<br>References Zhu, B., et al.: Steroids, 70, 225 (2005), Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997),<br></p>Formule :C19H26O2Couleur et forme :NeatMasse moléculaire :286.41Spiro[androsta-1,4-diene-6,2'-oxirane]-3,17-dione(Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of Exemestane (E957000).<br>References Cavalcanti, G. et al.: Steroids 76, 1010 (2011)<br></p>Formule :C20H24O3Couleur et forme :NeatMasse moléculaire :312.40Triamcinolone
CAS :Formule :C21H27FO6Couleur et forme :White To Light YellowMasse moléculaire :394.43Betamethasone-d5
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Glucocorticoid.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formule :C22H24D5FO5Couleur et forme :Off-White To Light YellowMasse moléculaire :397.49(-)-Estra-4,9-diene-3,17-dione
CAS :Produit contrôlé<p>Applications A potential metabolite of STS 557 (Dienogest)(D441870). A steroid with antiglucocorticoid activity.<br>References Kloosterboer, H., et al.: J. Steroid Biochem., 31, 567 (1988),<br></p>Formule :C18H22O2Couleur et forme :NeatMasse moléculaire :270.37Formestane
CAS :Produit contrôlé<p>Applications An antitumor drug. An aromatase inhibitor.<br>References Brodie, A.M. and Njar, V.C.: Steroids, 65, 171 (2000), Lonning, P.E., et al.: J. Steroid Biochem, 77, 39 (2001)<br></p>Formule :C19H26O3Couleur et forme :NeatMasse moléculaire :302.41(3α)-Allopregnanolone-d5
CAS :Produit contrôlé<p>Applications Labelled (3α)-Allopregnanolone. (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Formule :C21H29D5O2Couleur et forme :NeatMasse moléculaire :323.5217β-Estradiol-16,16,17-d3
CAS :Produit contrôlé<p>Applications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Formule :C182H3H21O2Couleur et forme :NeatMasse moléculaire :275.40(22S)-Budesonide
CAS :Produit contrôlé<p>Applications Budesonide (B689490) epimer S. Budesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formule :C25H34O6Couleur et forme :NeatMasse moléculaire :430.53Deltamedrane
CAS :<p>Stability Hygroscopic<br>Applications Deltamedrane is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Formule :C22H30O4Couleur et forme :BeigeMasse moléculaire :358.476a-Methyl Prednisolone 17-Propionate
CAS :Formule :C25H34O6Couleur et forme :White To Off-WhiteMasse moléculaire :430.53Latanoprost Acid-d4(>85%)
CAS :Produit contrôlé<p>Applications Latanoprost Acid-d4 is the labeled analogue of Latanoprost Acid (L177310), a metabolite of Latanoprost. Latanoprost Acid (L177310) is a potent, selective FP prostanoid receptor agonist, a F-series Prostaglandin analog and is 200 times as potent as isopropyl ester form.<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999), Kashiwagi, K., et al.: Exp. Eye Res., 74, 41 (2002),<br></p>Formule :C23H30D4O5Degré de pureté :>85%Couleur et forme :ColourlessMasse moléculaire :394.54Ciclesonide
CAS :Produit contrôlé<p>Applications A glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001),<br></p>Formule :C32H44O7Couleur et forme :White To Off-WhiteMasse moléculaire :540.6925-Hydroxy Vitamin D2
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D2 (V676040).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barnes, P., et al.: J. Clin. Invest., 83, 1527 (1989), Holick, M., et al.: J. Cell Biochem., 88(2), 296 (2003), Maunsell, Z., et al.: Clin. Chem., 51, 1683 (2005),<br></p>Formule :C28H44O2Couleur et forme :White To Light YellowMasse moléculaire :412.65Anecortave
CAS :<p>Impurity Hydrocortisone Acetate EP Impurity E<br>Applications Anecortave (Hydrocortisone Acetate EP Impurity E) is an angiostatic steroid. Used in treatment of macular degeneration.<br>References Clark, A.F., et al.: Expert Opin. Invest. Drugs, 6, 1867 (1997), Slakter, J.S., et al.: Ophthalmology 110, 2372 (2003),<br></p>Formule :C23H30O5Couleur et forme :BeigeMasse moléculaire :386.48Estrone-d4
CAS :Produit contrôlé<p>Applications Isotope labelled Estrone (E889050), which is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Formule :C18D4H18O2Couleur et forme :White SolidMasse moléculaire :274.39Mifepristone-d3
CAS :Produit contrôlé<p>Applications A labelled progesterone receptor antagonist with partial agonist activity. Abortifacient.<br>References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)<br></p>Formule :C29D3H32NO2Couleur et forme :Light Yellow SolidMasse moléculaire :432.6121-Desacetyl Deflazacort
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus.<br>References Hahn, T.J., et al.: Calcif. Tissue Int., 31, 109 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984)<br></p>Formule :C23H29NO5Couleur et forme :White To Off-WhiteMasse moléculaire :399.48Fulvestrant-d3
CAS :Produit contrôléFormule :C32H44D3F5O3SCouleur et forme :White To Off-WhiteMasse moléculaire :609.797-Keto Cholesterol
CAS :Produit contrôlé<p>Applications 7-Keto Cholesterol is a metabolite of Cholesterol.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),<br></p>Formule :C27H44O2Degré de pureté :~98%Couleur et forme :NeatMasse moléculaire :400.6417α-Hydroxy Progesterone
CAS :Produit contrôlé<p>Impurity Progesterone 17?-Hydroxy Impurity<br>Applications 17α-Hydroxy Progesterone is a metabolite of Progesterone (P755900). It was isolated from adrenal glands.<br>References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940), Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975),<br></p>Formule :C21H30O3Couleur et forme :Off-WhiteMasse moléculaire :330.46Corticosterone
CAS :Produit contrôlé<p>Applications Glucocorticoid; an intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.<br>References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),<br></p>Formule :C21H30O4Couleur et forme :NeatMasse moléculaire :346.465β-Dihydrocortisol-d6
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 5β-Dihydrocortisol-d6 is an isotope labelled analog of 5β-Dihydrocortisol (D448595). 5β-Dihydrocortisol, is a derivative of Cortisol (H714615), which is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Formule :C21H26D6O5Couleur et forme :NeatMasse moléculaire :370.51Betamethasone 17-Valerate
CAS :Produit contrôlé<p>Applications Betamethasone 17-Valerate is a corticosteroid with anti-inflammatory properties. Topical application of Betamethasone 17-Valerate has been shown to inhibit heat-induced vasodilatation in man.<br>References Banfi, S. et al.: Curr. Ther. Res., 19, 126 (1976); Ahluwalia, A. et al.: Br. J. Dermatol., 128, 45 (1993);<br></p>Formule :C27H37FO6Couleur et forme :WhiteMasse moléculaire :476.58Spironolactone-d3
CAS :Produit contrôlé<p>Applications Spironolactone-d3 is the labeled analogue of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975)<br></p>Formule :C24H29D3O4SCouleur et forme :Yellow SolidMasse moléculaire :419.596β-Hydroxy Testosterone
CAS :Produit contrôléFormule :C19H28O3Couleur et forme :WhiteMasse moléculaire :304.42Estradiol Benzoate
CAS :<p>Applications Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position. Estradiol benzoate is useful in the treatment of lesions produced by diminution of bodily production of estrogens.<br>References MacLusky, N., et al.: Endocrinology, 106, 192 (1980), Apostolakis, E., et al.: J. Neurosci., 16, 4823 (1996), Guarraci, F., et al.: Brain Res., 999, 40 (2004), Petralia, S., et al.: J. Neuroendocrinol., 18, 902 (2006),<br></p>Formule :C25H28O3Couleur et forme :WhiteMasse moléculaire :376.49Hexestrol-d4
CAS :Produit contrôlé<p>Applications Estrogen; antineoplastic (hormonal).<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 11, 347 (1982),<br></p>Formule :C182H4H18O2Couleur et forme :White To Off-WhiteMasse moléculaire :274.395a-Dihydrolevonorgestrel
CAS :Produit contrôlé<p>Applications 5α-Dihydrolevonorgestrel is the reduced analogue of levonorgestrel (N689510), a safe, tolerated and effective emergency contraceptive for women.<br>References Cabeza, M., et al.: Steroids., 60, 630 (1995); Lemus, A.E., et al.: J. Steroid. Biochem. Molec. Biol., 41,881 (1992); Bergink. E.W., et al.: J. Steroids. Biochem., 14, 175 (1981);<br></p>Formule :C21H30O2Couleur et forme :NeatMasse moléculaire :314.46Levonorgestrel EP Impurity P
CAS :<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Wate</p>Degré de pureté :90% minCouleur et forme :Off White or Beige SolidMasse moléculaire :312.45β-Epoxyabiraterone acetate
CAS :<p>Beta-Epoxyabiraterone acetate is a synthetic and natural metabolite of abiraterone that is used as an API impurity in the synthesis of abiraterone acetate. The drug product is a niche compound with CAS No. 52464-96-6. The Metabolite is an impurity found in the synthesis of beta-epoxyabiraterone acetate. Drug development research and development, analytical methods, and pharmacopoeia are all involved in the production of this compound.</p>Formule :C26H33NO3Degré de pureté :Min. 90 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :407.55 g/molAtorvastatin methyl ester
CAS :<p>Atorvastatin methyl ester is a statin drug that inhibits the synthesis of cholesterol and other lipids in the body. It is used to reduce high levels of low-density lipoprotein (LDL) cholesterol, which may lead to heart disease or stroke. Atorvastatin methyl ester has been shown to be effective in reducing the uptake of LDL cholesterol into cells by preventing the formation of LDL particles. This drug also decreases the production of biphosphate-containing phospholipids, which are essential for dendritic cell maturation. The crystalline polymorphs have been characterized by X-ray diffraction and microscopy. Impurities can be detected using ultraviolet spectroscopy, infrared spectroscopy, or nuclear magnetic resonance spectroscopy.</p>Formule :C34H37FN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :572.67 g/molLevonorgestrel EP Impurity O
CAS :<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Water</p>Degré de pureté :95.0% MinCouleur et forme :Off White or Beige SolidMasse moléculaire :344.49Atorvastatin epoxy tetrahydrofuran impurity
CAS :<p>Atorvastatin epoxy tetrahydrofuran impurity is a byproduct of the synthesis process. It is a white crystalline powder that is soluble in organic solvents and sparingly soluble in water. Atorvastatin epoxy tetrahydrofuran impurity has been shown to be an impurity of atorvastatin. It is not known to have any biological activity, but it may pose a health risk if present in large quantities.</p>Formule :C26H24FNO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :449.47 g/molO-Methyl atorvastatin calcium
CAS :<p>O-Methyl atorvastatin calcium is a drug product that is an HPLC standard. It is a natural metabolite of atorvastatin, which is synthesized by cytochrome P450 3A4 in the liver. O-Methyl atorvastatin calcium has been shown to be an impurity in some batches of atorvastatin calcium. It has been observed to have pharmacological effects similar to those of atorvastatin. O-Methyl atorvastatin calcium has been used as a research and development (R&D) tool for studies on the metabolism of drugs, including its own synthesis and the study of the effect on other drugs such as amiodarone.</p>Formule :CaC68H71F2N4O10Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,182.39 g/mol1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3] oxazine-3-butanoic acid sodium
CAS :<p>Fluoxetine is a selective serotonin reuptake inhibitor that is used to treat major depressive disorder, obsessive-compulsive disorder (OCD), bulimia nervosa, panic disorder, premenstrual dysphoric disorder (PMDD), and social anxiety disorder. It is also used as an appetite suppressant in some countries. Fluoxetine inhibits the neuronal uptake of serotonin by blocking the presynaptic transporter protein. The most common adverse effects are nausea, diarrhea, drowsiness, dry mouth, blurred vision and sexual dysfunction.</p>Formule :C33H35FN2O7•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :613.63 g/mol3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid
CAS :<p>3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid is a covalently bonded prodrug that is metabolized to its active form, finasteride, in the body. It has been shown to have physiological activities such as skin permeation and cell growth. 3-Oxo-4-aza-5a-androst-1-ene 17b carboxylic acid also has immunotherapy properties and can be conjugated with other compounds for use in cancer treatment.</p>Formule :C19H27NO3Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :317.42 g/mol(3S,5S)-Atorvastatin sodium salt
CAS :<p>Atorvastatin is a statin drug that inhibits the enzyme HMG-CoA reductase, which is responsible for cholesterol synthesis. Atorvastatin is used to lower LDL cholesterol and total cholesterol levels in the blood. It also lowers triglyceride levels and raises HDL cholesterol levels. Atorvastatin has been shown to inhibit fibrinogen production, reduce TNF-α production, and improve body mass index (BMI) in obese patients. This drug has been shown to be effective in reducing the size of atherosclerotic lesions by decreasing the amount of cholesteryl esters transferred from high-density lipoprotein (HDL) to low-density lipoprotein (LDL). It has also been shown to inhibit collagen production and stimulate muscle cell proliferation.</p>Formule :C33H34FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :580.62 g/molDefluoro atorvastatin acetonide tert-butyl ester
CAS :<p>Please enquire for more information about Defluoro atorvastatin acetonide tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C40H48N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :636.82 g/molVitamin A EP Impurity C
CAS :<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Wate</p>Degré de pureté :90% minCouleur et forme :Off White or Beige SolidMasse moléculaire :312.45Atorvastatin lactam sodium salt impurity
CAS :<p>Atorvastatin is a drug used for the treatment of hypercholesterolemia and cardiovascular diseases. Atorvastatin lactam, which is an impurity formed during the synthesis of atorvastatin, has been shown to inhibit cholesterol biosynthesis in a rat model. The in vivo metabolism of atorvastatin lactam was studied by HPLC-MS/MS and was found to be identical to that of the parent molecule. This impurity may be useful as a research and development or custom synthesis product, or as an impurity standard for HPLC analysis.</p>Formule :C33H34FN2NaO6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :596.62 g/molDefluoro atorvastatin calcium
CAS :<p>Defluoro atorvastatin calcium is a bulk drug that has been approved to be used as an adjunct to diet to reduce elevated cholesterol levels in adults. Defluoro atorvastatin calcium is the desfluoro-enantiomer of atorvastatin, which is a statin that inhibits the enzyme HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonic acid, which is an early step in the synthesis of cholesterol. The fluoro group on defluoro atorvastatin calcium is not expected to have any significant effect on its potency or metabolic pathways and any impurities are not expected to have any therapeutic effect.</p>Formule :C66H70CaN4O10Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :1,119.36 g/molrac-3-Oxo atorvastatin sodium salt
CAS :<p>Racemic 3-Oxo atorvastatin sodium salt (3OAS) is a drug product that has been tested in the laboratory and found to be suitable for further development. It is a natural substance that has not been chemically synthesized. Racemic 3-Oxo atorvastatin sodium salt is an impurity standard that can be used to establish the purity of API drugs. It can also be used as a metabolite in metabolism studies. Racemic 3-Oxo atorvastatin sodium salt is high purity and can be used for niche applications such as pharmacopoeia production.</p>Formule :C33H32FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :578.61 g/molCalcipotriol EP impurity E
<p>Calcipotriol EP Impurity E is a synthetic impurity that is found in the calcipotriol EP API. Calcipotriol EP Impurity E is an impurity standard for HPLC and can be used in drug development, research and development, and pharmacopoeia. It has been shown to have no significant effect on the pharmacological activity of calcipotriol EP.</p>Formule :C27H42O3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :414.62 g/molAtorvastatin EP Impurity D
CAS :<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Water</p>Degré de pureté :95.0% MinCouleur et forme :White or Off-White Crystalline Solid, Light SensitiveMasse moléculaire :431,46Dutasteride impurity F
CAS :<p>Dutasteride impurity D is a natural impurity found in dutasteride and has been reported to be an analytical marker for dutasteride. It is also used as an impurity standard, HPLC standard, and custom synthesis for drug development. Metabolism studies have shown that the major route of elimination for Dutasteride impurity D is through glucuronidation with minor amounts being excreted in urine unchanged.</p>Formule :C27H31ClF6N2O2Degré de pureté :Min. 95 Area-%Masse moléculaire :564.99 g/molAtorvastatin impurity F
CAS :<p>Atorvastatin impurity F is an impurity that can be found in atorvastatin. It is a white to off-white crystalline solid with a melting point of 142°C. It has a molecular weight of 273.5 and chemical formula of C14H13N3O2. This impurity can be found in atorvastatin as an API impurity, which may have an effect on the efficacy or toxicity of the drug product. Impurities are present in all pharmaceutical products and should be identified, characterized, and quantified for quality control purposes. Impurities are often unavoidable byproducts of the manufacturing process and can lead to potential safety concerns if they are not detected early on during drug development. The presence of impurities may also affect the pharmacological effects or therapeutic efficacy of the drug product.</p>Formule :C40H47FN3O8NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :739.8 g/mol(betaS,deltaS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1)
CAS :<p>(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1) is a fluorinated derivative of the natural metabolite 2-(4-fluorophenyl)-beta,delta-dihydroxy -5-(1 methylethyl)-3 phenyl 4-[(phenylamino)carbonyl]-1H pyrrole 1 heptanoic acid. It is an enantiomer of the racemate with optical purity > 98%. The compound has been used as a pharmacological and supramolecular chemistry probe for assays and chemosensors.</p>Formule :C66H68CaF2N4O10Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :1,155.34 g/molDifluoro atorvastatin
CAS :<p>Difluoro atorvastatin is a filtrate of atorvastatin, which is a cholesterol-lowering drug. It is synthesized by reacting butyric acid with atorvastatin in an organic solvent. The reaction solution was filtered to remove impurities and then purified by liquid chromatography. The product was characterized by diffraction and LC-MS analysis. Difluoro atorvastatin has a high purity and is suitable for further use in the preparation of pharmaceuticals.</p>Formule :C33H34F2N2O5Degré de pureté :Min. 95%Masse moléculaire :576.63 g/molCalcipotriol EP Impurity H
<p>Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.</p>Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :807.19 g/molFluticasone propionate EP Impurity F
CAS :<p>Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man.<br>br>br><br>The following table summarizes the metabolic pathways that have been identified for this impurity:<br>br>br><br>Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-d</p>Formule :C25H29F3O5SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :498.56 g/molAtorvastatin epoxydione impurity
CAS :<p>Atorvastatin epoxydione impurity (EPI) is a heptanoic, hydrate, diastereoisomer, racemic mixture, enantiomer and impurity of Atorvastatin. The EPI has been minimized in the formulation process by using a novel synthesis route that employs a chiral pyrrole derivative as an intermediate. This minimization has allowed for the elimination of the tautomer and other impurities present in the original compound.</p>Formule :C26H22FNO4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :431.46 g/mol(3R,5S)-Atorvastatin sodium salt
CAS :<p>(3R,5S)-Atorvastatin sodium salt is a synthetic compound that is used in the treatment of high cholesterol. It belongs to the class of statins, which are used for lowering blood cholesterol levels. The drug product contains at least 99% by weight of (3R,5S)-atorvastatin sodium salt. This product also has an analytical purity greater than 98%. It is metabolized via oxidation and hydroxylation to form metabolites that exhibit pharmacological activity similar to the parent molecule. (3R,5S)-Atorvastatin sodium salt is a natural product that can be found in plants such as yew trees. This drug has been shown to have niche applications in drug development and research and development.</p>Formule :C33H34FN2NaO5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :580.62 g/molDesfluoro atorvastatin
CAS :<p>Desfluoro atorvastatin is a crystalline polymorph of atorvastatin that has been shown to have improved flowrate and dissolution profile compared with the conventional form. Desfluoro atorvastatin is synthesized by adding a fluorine atom to a specific position in the molecule. The synthesis procedure includes chromatographic purification and analysis of impurities, which are then eliminated by diode laser irradiation. Impurities may also be eliminated through hydrogenation or recrystallization.</p>Formule :C33H36N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :540.65 g/molCalcipotriol EP Impurity G
<p>Calcipotriol EP Impurity G is an impurity in calcipotriol, which is a drug product. Calcipotriol EP Impurity G has a CAS number of 126825-26-3 and is a natural metabolite of calcipotriol. It is also known as calcipotriol EP Impurity G or calcipotriol EPIG. It has been shown to be an analytical impurity in calcipotriol, and it has been detected by HPLC analysis. Calcipotriol EP Impurity G can be used for research and development, as well as for the production of pharmacopoeia standards.</p>Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :807.19 g/molAtorvastatin epoxy pyrrolooxazin tricyclic impurity
<p>Atorvastatin is a drug product that is metabolized to atorvastatin epoxy pyrrolooxazin tricyclic impurity. Due to the presence of this impurity, the purity of the drug product is not 100%. Atorvastatin epoxy pyrrolooxazin tricyclic impurity is a natural metabolite with CAS number 516-80-1. It has been shown to have effects on metabolism and may be involved in the development of atherosclerosis. Metabolism studies have been conducted on animals, but not humans.</p>Formule :C33H32FN2NaO6Degré de pureté :Min. 95%Masse moléculaire :594.61 g/molCalcipotriol EP Impurity B
<p>Calcipotriol EP Impurity B is a drug product that is an impurity in Calcipotriol EP. It is produced during the synthesis of calcipotriol and may be present in the natural product. It has been shown to have anti-inflammatory properties, and can be used as a research tool to study calcipotriol metabolism.</p>Formule :C27H40O3Degré de pureté :Min. 95%Masse moléculaire :412.6 g/molAtorvastatin lactone
CAS :<p>Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.</p>Formule :C33H33FN2O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :540.62 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS :Produit contrôlé<p>(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.</p>Formule :C24H31NODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :349.51 g/molBexarotene
CAS :<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Formule :C24H28O2Degré de pureté :99% - 99.65%Couleur et forme :White SolidMasse moléculaire :348.48Travoprost
CAS :<p>Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.</p>Formule :C26H35F3O6Degré de pureté :97.39% - 99.58%Couleur et forme :Colorless OilMasse moléculaire :500.55Atorvastatin
CAS :<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formule :C33H35FN2O5Degré de pureté :99.37% - 99.69%Couleur et forme :SolidMasse moléculaire :558.64(R)-4-((5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS :Degré de pureté :95%Masse moléculaire :392.58rac 7-Methoxy Lasofoxifene
CAS :Produit contrôlé<p>Applications Lasofoxifene intermediate.<br>References Rosati, R., et al.: J. Med. Chem., 41, 2928 (1998),<br></p>Formule :C29H33NO2Couleur et forme :NeatMasse moléculaire :427.586a-Hydroxy Levonorgestrel
CAS :<p>Impurity Levonorgestrel EP Impurity G<br>Applications 6α-Hydroxy Levonorgestrel (Levonorgestrel EP Impurity G) is a hydroxylated impurity of Norgestrel (N689500).<br>References Lin, Y., et al.: Biochim. Biophys. Acta, 218, 526 (1970), Smith, K., et al.: J. Steroid Biochem., 32, 445 (1989), Hu, S., et al.: Steroids, 60, 337 (1995),<br></p>Formule :C21H28O3Couleur et forme :White SolidMasse moléculaire :328.4421-Carboxy Dexamethasone
CAS :<p>Applications 21-Carboxy Dexamethasone is a useful research chemical.<br>References Shepard, Allan R., ACS Chem. Biol., 3, 549-558(2013);<br></p>Formule :C22H27FO6Couleur et forme :White To Off-WhiteMasse moléculaire :406.44Vitamin D3 b-D-Glucuronide, >90%
CAS :Produit contrôlé<p>Stability Temperature and Light Sensitive<br>Applications A metabolite of Vitamin D3.<br>References Bell, P.A., et al.: Biochem. J., et al.: 115, 663 (1969), Kumar, R.S., et al.: J. Clin. Invest., 65, 277 (1980), Shimada, K., et al.: Biol. Pharm. Bull., 19, 491 (1996),<br></p>Formule :C33H52O7Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :560.76Ciclesonide-d11 (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.This compound is a mixture of diastereomers at the cyclohexyl acetal.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formule :C32D11H33O7Couleur et forme :NeatMasse moléculaire :551.76Exemestane-13C,D3
CAS :Produit contrôlé<p>Applications Exemestane-13C,D3 is the labeled analogue of Exemestane (E957000), an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formule :C1913CH21D3O2Couleur et forme :NeatMasse moléculaire :300.416,7-Dihydrocanrenone
CAS :Produit contrôléFormule :C22H30O3Couleur et forme :NeatMasse moléculaire :342.47(4S,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS :Produit contrôlé<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>Formule :C14H27NO4Couleur et forme :NeatMasse moléculaire :273.37Estradiol 3-Valerate
CAS :Produit contrôlé<p>Applications Estradiols ester used in polymeric matrix for transdermal treatment of osteoporosis.<br>References Tripathi, V.N., et al.: Can. J. Animal Sci., 48, 449 (1968),<br></p>Formule :C23H32O3Couleur et forme :NeatMasse moléculaire :356.5113-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol(Levo Norgestrel Impurity)
CAS :Produit contrôlé<p>Impurity Levonorgestrel EP Impurity C<br>Applications 13-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol (Levonorgestrel EP Impurity C) is an impurity of Levonorgestrel.<br></p>Formule :C23H28OCouleur et forme :NeatMasse moléculaire :320.4716-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregn-4-ene-3,11-dione
CAS :Produit contrôléFormule :C24H32O6Couleur et forme :NeatMasse moléculaire :416.51Estriol 16a,17b-Diacetate
CAS :Produit contrôlé<p>Applications Estriol 16α,17β-Diacetate is a diacetate derivative of Estriol (E888960); an estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929); Huffman, et al.: J. Biol. Chem., 169, 167 (1947)<br></p>Formule :C22H28O5Couleur et forme :NeatMasse moléculaire :372.4511β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
Produit contrôlé<p>Applications A labelled metabolite of Budesonide (B689490), an antiinflammatory agent.<br>References Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000), Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007), Buchwald, P., et al.: Steroids, 73, 193 (2008),<br></p>Formule :C21H25D3O6Couleur et forme :NeatMasse moléculaire :379.46(16α)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS :Produit contrôléFormule :C24H30O6Couleur et forme :NeatMasse moléculaire :414.49(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
CAS :Produit contrôlé<p>Applications (3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate is an intermediate in the synthesis of Prostaglandin E2 (P838610), the most common and biologically potent of mammalian prostaglandins.<br>References Radeuchel, B., et al.: Tetrahedron. Lett., 633, 9 (1975);<br></p>Formule :C21H18O5Couleur et forme :NeatMasse moléculaire :350.3646(5E)-Calcipotriene
CAS :Produit contrôlé<p>Impurity Calcipotriol EP Impurity C<br>Stability Temperature Sensitive<br>Applications The trans-isomeric impurity of Calcipotriene (C144200) and a vitamin D3 analogue with antitumor effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wietrzyk, J. et al.: Anti-Cancer Drugs, 18, 447 (2007); Wietrzyk, J. et al.: Anticancer Res., 27, 3387 (2007); Filip, B. et al.: J. Ster. Biochem. Mol. Biol., 121, 399 (2010);<br></p>Formule :C27H40O3Couleur et forme :NeatMasse moléculaire :412.603-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester
CAS :Produit contrôlé<p>Impurity Finasteride EP Impurity B<br>Applications 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.<br>References Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),<br></p>Formule :C20H29NO3Couleur et forme :White To Off-WhiteMasse moléculaire :331.45∆9,11-Dehydro-17α-cyanomethyl Estradiol
CAS :Produit contrôlé<p>Applications ∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.<br>References Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);<br></p>Formule :C20H23NO2Couleur et forme :NeatMasse moléculaire :309.40(3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid
CAS :<p>Applications Latanoprost Enol is an impurity of Latanoprost (L177280), a prostaglandin analogue used to treat glaucoma and other degenerative diseases of the eye.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993);<br></p>Formule :C31H30O5Couleur et forme :NeatMasse moléculaire :482.57Dexamethasone acetate monohydrate
CAS :<p>Dexamethasone acetate treats rheumatic issues, skin conditions, asthma, allergies, COPD, brain swelling, croup, TB adjunct.</p>Formule :C24H33FO7Couleur et forme :SolidMasse moléculaire :452.523-(N-Phenyl-N-methyl)aminoacrolein
CAS :<p>3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.</p>Formule :C10H11NODegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :161.2 g/mol(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
CAS :Formule :C24H40O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.58Sodium taurodeoxycholate monohydrate
CAS :Formule :C26H46NNaO7SDegré de pureté :95%Masse moléculaire :539.76α-Hydroxy Testosterone-d3
CAS :Produit contrôléFormule :C19H25D3O3Couleur et forme :NeatMasse moléculaire :307.4415-Keto Latanoprost
CAS :<p>Applications 15-Keto Latanoprost is a metabolite of Latanoprost (L177280).<br>References Sjoquist, B., et al.: Drug Metab. Dispos., 26, 745 (1998), Watson, P., et al.: Drugs Today, 35, 449 (1999),<br></p>Formule :C23H30O5Couleur et forme :NeatMasse moléculaire :386.4817α-Hydroxyprogesterone Valerate
CAS :Produit contrôlé<p>Applications 17α-Hydroxy-progesterone Valerate acts as a synthetic Progesterone (P755900) reducing the chance of pre-term birth in women. Progesterone is a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formule :C26H38O4Couleur et forme :NeatMasse moléculaire :414.58δ6-Gestodene
Produit contrôlé<p>Applications Δ6-Gestodene, is an impurity of Gestodene (G368250), an orally active gestogen with progesterone-like profile of activity. Used in combination with estrogen as oral contraceptive.<br>References Duesterberg, B., et al.: Contraception, 24, 673 (1981); Duesterberg, B., et al.: Seroids, 43, 43 (1984); Losert, W., et al.: Arzneim.-Forsch., 35, 459 (1985);<br></p>Formule :C21H24O2Couleur et forme :NeatMasse moléculaire :308.4125-Hydroxy Vitamin D3 3,3'-Biotinylaminopropyl Ether
CAS :<p>Applications Vitamin D3 (V676045) analog.<br>References Roy, A., et al.: Steroids, 60, 530 (1995);<br></p>Formule :C40H65N3O4SCouleur et forme :NeatMasse moléculaire :684.032-Hydroxy Atorvastatin Lactone
CAS :Produit contrôlé<p>Impurity Atorvastatin 2-Hydroxy Lactone<br>Stability Hygroscopic<br>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br></p>Formule :C33H33FN2O5Couleur et forme :Off White SolidMasse moléculaire :556.622-Hydroxy-estrone-6-N3-adenine (90%)
CAS :Produit contrôlé<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formule :C23H25N5O3Degré de pureté :90%Couleur et forme :NeatMasse moléculaire :419.48a-Epoxyabiraterone Acetate
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications α-Epoxyabiraterone Acetate is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Formule :C26H33NO3Couleur et forme :NeatMasse moléculaire :407.556b-Methyl Fluorometholone
CAS :Produit contrôlé<p>Stability Not stable in Acidic or basic condition<br>Applications 6β-Methyl Fluorometholone is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formule :C22H29FO4Couleur et forme :NeatMasse moléculaire :376.46δ6-Fulvestrant
CAS :Produit contrôlé<p>Impurity Fulvestrant Impurity E;<br>Applications Fulvestrant (F862500) impurity E.<br></p>Formule :C32H45F5O3SCouleur et forme :NeatMasse moléculaire :604.75Bexarotene-13C4
CAS :Produit contrôlé<p>Applications Labelled Bexarotene (B336750). Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.<br>References Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994), Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1996), Mukherjee, R., et al.: Nature, 386, 407 (1997), Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)<br></p>Formule :C4C20H28O2Couleur et forme :NeatMasse moléculaire :352.45Deflazacort-d3 (Major)
CAS :Produit contrôléFormule :C25H28D3NO6Couleur et forme :NeatMasse moléculaire :444.54Desisobutyryl Ciclesonide
CAS :Produit contrôlé<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formule :C28H38O6Couleur et forme :White To Off-WhiteMasse moléculaire :470.606β-Hydroxymethylandrosta-1,4-diene-3,17-dione
CAS :Produit contrôléFormule :C20H26O3Couleur et forme :White To Off-WhiteMasse moléculaire :314.42Testosterone-16,16,17-d3 17-Decanoate
CAS :Produit contrôlé<p>Applications Testosterone 17-Decanoate-d3, is the labeled analogue of Testosterone 17-Decanoate (T155120), an ester of Testosterone (T155000). Testosterone 17-Decanoate, can be used as a potential long-acting male contraceptive, with the combination of subcutaneous etonogestrel implants.<br>References Brady, B. M., et al.: Human Reproduction, 21 (1), 285 (2006); Themmen, A., et al.: Endocr. Rev. 21, 551 (2000);<br></p>Formule :C292H3H43O3Couleur et forme :NeatMasse moléculaire :445.69Testosterone-d8
CAS :Produit contrôlé<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Formule :C19H20D8O2Couleur et forme :White To Off-WhiteMasse moléculaire :296.47Fulvestrant 17-Ketone
CAS :Produit contrôlé<p>Applications Fulvestrant 17-Ketone, is an impurity of Fulvestrant (F862500), a novel steroidal estrogen antagonist reported to lack any partial agonist activity. Antineoplastic (hormonal).<br>References Wakeling, A.E., et al.: Cancer Res., 51, 3867 (1991), Howell, A., et al.: Br. J. Cancer, 74, 300 (1996), Robertson, J.F., et al.: Cancer Res., 61, 6739 (2001),<br></p>Formule :C32H45F5O3SCouleur et forme :NeatMasse moléculaire :604.75Estriol 3,16a,17b-Triacetate
CAS :Produit contrôlé<p>Applications Estriol 3,16α,17β-Triacetate is a triacetate derivative of Estriol (E888960) with contraceptive activity.<br>References Wotiz, H.H., et al.: J. Reprod. Fertil., 26, 363 (1971)<br></p>Formule :C24H30O6Couleur et forme :NeatMasse moléculaire :414.49Epoxy Metradiene
CAS :Produit contrôlé<p>Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);<br></p>Formule :C22H28O4Couleur et forme :NeatMasse moléculaire :356.4620-Dihydroprogesterone Acetate
CAS :Produit contrôlé<p>Impurity Progesterone EP Impurity E<br>Applications 20-Dihydroprogesterone Acetate (Progesterone EP Impurity E) is an analogue of Progesterone (P755900), a steroid used in cardiovascular and menopausal studies.<br>References Grodstein, F. et al.: New. Eng. J. Med., 335, 453 (1996); Cushman, M. et al.: Circulation, 100, 717 (1999);<br></p>Formule :C23H34O3Couleur et forme :NeatMasse moléculaire :358.512-Methyl Ethynyl Estradiol
CAS :Produit contrôlé<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Formule :C21H26O2Couleur et forme :NeatMasse moléculaire :310.4325-Hydroxy Cholesterol-d6
CAS :Produit contrôlé<p>Applications 25-Hydroxy Cholesterol-d6, is the labeled analogue of 25-Hydroxy Cholesterol (H918030), which is an oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It also induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.<br>References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);<br></p>Formule :C272H6H40O2Couleur et forme :NeatMasse moléculaire :408.691,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS :<p>Stability Hygroscopic<br>Applications A degradation product of Betamethasone (B327000).<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Formule :C28H39FO7Couleur et forme :NeatMasse moléculaire :506.60(16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione
CAS :Produit contrôlé<p>Applications (16α)-21-[(Ethoxycarbonyl)oxy]-17-hydroxy-16-methylpregna-1,4,9(11)-triene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Formule :C25H32O6Couleur et forme :NeatMasse moléculaire :428.526-Keto Dexamethasone
Produit contrôlé<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Formule :C22H27FO6Couleur et forme :NeatMasse moléculaire :406.44Fluticasone-d3 17β-Carboxylic Acid
CAS :Produit contrôléFormule :C21H23D3F2O5Couleur et forme :NeatMasse moléculaire :399.44Desogestrel
CAS :Produit contrôlé<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formule :C22H30OCouleur et forme :White To Off-WhiteMasse moléculaire :310.47Gestonorone Capronate
CAS :Produit contrôléFormule :C26H38O4Couleur et forme :NeatMasse moléculaire :414.58D-Homoanalog of Triamcinolone
CAS :Produit contrôlé<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Formule :C21H27FO6Couleur et forme :NeatMasse moléculaire :394.43Prednisolone 21-Sulfate Sodium Salt
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Prednisolone 21-Sulfate is a metabolite of Prednisolone (P703740).<br>References Hutzler, J., ET AL.: Drug Metab. Dispos., 30, 355 (2002), Sugiyama, D., et al.: J. Biol. Chem., 278, 43489 (2003), Hagenbuch, B., et al.: Xenobiotica, 38, 778 (2008),<br></p>Formule :C21H27NaO8SCouleur et forme :NeatMasse moléculaire :462.49(11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione
CAS :Produit contrôlé<p>Applications (11β)-9-Fluoro-11,21-dihydroxy-16-methyl-pregna-1,4,16-triene-3,20-dione is a derivative of Dexamethasone (D298800), an anti-inflammatory glucocorticoid.<br>References Kodelja, V., et al.: J. Immunol., 160, 1411 (1998), Metselaar, J., et al.: Arthritis Rheum., 48, 2059 (2003), Buttgereit, F., et al.: Arthritis Rheum., 50, 3408 (2004), Martinez, F., et al.: Front Biosci., 13, 453 (2008),<br></p>Formule :C22H27FO4Couleur et forme :WhiteMasse moléculaire :374.457-(Desacetothioxy)-7-acetodithioperoxy-spironolactone
Produit contrôléFormule :C24H32O4S2Couleur et forme :NeatMasse moléculaire :448.64Testosterone (1mg/ml in Acetonitrile)
CAS :Produit contrôléFormule :C19H28O2Couleur et forme :ColourlessMasse moléculaire :288.42N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS :Produit contrôlé<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formule :C25H38N2O2Couleur et forme :NeatMasse moléculaire :398.58Dexamethasone 21-Palmitate
CAS :Produit contrôlé<p>Applications A corticosteroid prodrug for the treatment of eye disorders.<br>References Benameur, H., et al.: J. Pharm. Pharmacol., 47, 812 (1995), Tauchi, Y., et al.: Biol. Pharm. Bull., 24, 925 (2001), Chono, S., et al.: J. Drug Targeting, 13, 407 (2005),<br></p>Formule :C38H59FO6Couleur et forme :NeatMasse moléculaire :630.87Betamethasone 21-Acetate-d3
CAS :Produit contrôlé<p>Applications Betamethasone 21-Acetate-d3, is the labeled analogue of Betamethasone 21-Acetate (B327025), which is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formule :C24H28D3FO6Couleur et forme :NeatMasse moléculaire :437.5217α-Methyl-4-[(phenylthio)methyl]testosterone
CAS :Produit contrôlé<p>Applications Testosterone (T155000) derivative.<br></p>Formule :C27H36O2SCouleur et forme :NeatMasse moléculaire :424.64(E/Z)-17-Deacetylnorgestimate
CAS :Produit contrôléFormule :C21H29NO2Couleur et forme :NeatMasse moléculaire :327.46Dexamethasone Oxetanone
CAS :Produit contrôlé<p>Applications Dexamethasone Oxetanone is a potent antiglucocorticoid.<br>References Lamontagne, N., et al.: Endocrinology, 114, 2252 (1984);<br></p>Formule :C22H27FO4Couleur et forme :NeatMasse moléculaire :374.45Dexamethasone 17-Propionate
CAS :Produit contrôlé<p>Applications A Dexamethasone Dipropionate metabolite.<br>References Miyachi, Y., et al.: Steroids, 52, 137 (1988), Soh H., et al.: Brit. J. dermatol., 125, 73 (1991), Civiale, C., et al.: J. Ocul. Pharmacol., Thera., 20, 75 (2004),<br></p>Formule :C25H33FO6Couleur et forme :NeatMasse moléculaire :448.52(3(α))-Allopregnanolone 3-(β)-DGlucuronide
CAS :Produit contrôlé<p>Applications (3α)-Allopregnanolone 3-β-D-Glucuronide is the glucuronide conjugate of (3α)-Allopregnanolone (A547100), metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References Martin, F. et al.: LJ Steroid Biochem., 6, 1339 (1975); Lin, M.T. et al.: Steroids, 32, 547 (1978);<br></p>Formule :C27H42O8Couleur et forme :NeatMasse moléculaire :494.62Digitoxigenin Mono-β-D-digitoxoside
CAS :Produit contrôléFormule :C29H44O7Couleur et forme :White To Off-WhiteMasse moléculaire :504.66Dexamethasone Phosphate Bisulfate Adduct Sodium Salt
CAS :Formule :C22H32FO11PS•xNaCouleur et forme :NeatMasse moléculaire :554.5222986α-Hydroxy Gestrinone Glucuronide
CAS :Produit contrôléFormule :C27H32O9Couleur et forme :Light YellowMasse moléculaire :500.5411b-Hydroxy Etiocholanolone
CAS :Produit contrôlé<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Formule :C19H30O3Couleur et forme :White To Off-WhiteMasse moléculaire :306.446-Oxo Boldione
CAS :Produit contrôlé<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formule :C19H22O3Couleur et forme :Off-White To Light YellowMasse moléculaire :298.38Fluocinolone Acetonide-13C3
CAS :Produit contrôléFormule :C2113C3H30F2O6Couleur et forme :NeatMasse moléculaire :455.47Betamethasone 21-Mesylate (>90%)
CAS :Produit contrôléFormule :C23H31FO7SDegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :470.553β,5α-Tetrahydrodeoxycorticosterone
CAS :<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Formule :C21H34O3Couleur et forme :White To Off-WhiteMasse moléculaire :334.49Ciclesonide-d7
CAS :Produit contrôlé<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formule :C32H37D7O7Couleur et forme :NeatMasse moléculaire :547.73(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS :Produit contrôlé<p>Applications Glucocorticoid.<br></p>Formule :C22H28O4Couleur et forme :NeatMasse moléculaire :356.469α-Bromobudesonide
CAS :Produit contrôlé<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>Formule :C25H33BrO6Couleur et forme :NeatMasse moléculaire :509.43Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Formule :C33H33FN2O6Couleur et forme :NeatMasse moléculaire :572.6220β-Dihydrocortisone
CAS :Produit contrôlé<p>Applications 20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Reach, G., et. al.: Steroids, 30, 621 (1977); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)<br></p>Formule :C21H30O5Couleur et forme :NeatMasse moléculaire :362.46a,a,a-Trifluorotoluene
CAS :Produit contrôlé<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formule :C7H5F3Couleur et forme :ColourlessMasse moléculaire :146.1117α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS :Produit contrôlé<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Formule :C20H24F2O4Couleur et forme :NeatMasse moléculaire :366.423-Hydroxybudesonide
CAS :Produit contrôlé<p>Applications 23-Hydroxybudesonide is an metabolite of budesonide (B689490), a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.<br>References Edsbaecker, S., et al.: Drug. Metabol. Dispostion., 15, 403 (1987); Moore, C.D., et al.: Drug. Metabolism. Disposition., 41, 379 (2013);<br></p>Formule :C25H34O7Couleur et forme :NeatMasse moléculaire :446.5317β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS :Produit contrôlé<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Formule :C26H31D3O8Couleur et forme :NeatMasse moléculaire :477.5620-Hydroxydexamethasone
CAS :Produit contrôléFormule :C22H31FO5Couleur et forme :NeatMasse moléculaire :394.48Estrone-2,4-d2
CAS :Produit contrôlé<p>Applications Estrone-2,4-d2 (CAS# 350820-16-5) is a useful isotopically labeled research compound.<br></p>Formule :C182H2H20O2Couleur et forme :NeatMasse moléculaire :272.38(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS :Produit contrôléFormule :C18H24O4Couleur et forme :NeatMasse moléculaire :304.3813-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (~90%) (Levo Norgestrel Impurity)
CAS :Produit contrôlé<p>Impurity Levonorgestrel EP Impurity D<br>Applications 13-Ethyl-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Levonorgestrel EP Impurity D) is an impurity of Levonorgestrel.<br>References McGinty, D., et al.: Endocrinology, 24, 829 (1939), Belanger, A., et al.: Steroids, 37, 361 (1981), Nieman, L., et al.: J. Clin. Endocrinol. Metab., 61, 536 (1985), Klebe, G., et al.: J. Med. Chem., 37, 4130 (1994),<br></p>Formule :C21H30OCouleur et forme :NeatMasse moléculaire :298.464-Hydroxy Estradiol 1-N3-Adenine
CAS :Produit contrôlé<p>Applications 4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formule :C23H27N5O3Couleur et forme :NeatMasse moléculaire :421.49(3E)-17-Deacetylnorgestimate
CAS :<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Formule :C21H29NO2Couleur et forme :Off-WhiteMasse moléculaire :327.46
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