Nucléosides et Nucléotides
Les nucléosides sont des composés formés par une base azotée liée à un sucre (ribose ou désoxyribose). Lorsqu’un groupe phosphate est ajouté au nucléoside, un nucléotide est formé. Ces composés sont essentiels en biologie cellulaire, car les nucléotides sont les blocs fondamentaux de l’ADN et de l’ARN, responsables du stockage et de la transmission de l’information génétique. Les nucléosides ont des applications dans le traitement des maladies virales, en tant qu’inhibiteurs de la réplication virale. Les nucléotides, en plus de leur rôle structurel dans les acides nucléiques, interviennent dans les processus énergétiques, comme la synthèse de l’ATP.
Chez CymitQuimica, nous proposons une large gamme de nucléosides et de nucléotides essentiels à la recherche en biologie moléculaire, virologie et pharmacologie.
3420 produits trouvés pour "Nucléosides et Nucléotides"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
1-Methyl-4-nitro-5-thioimidazole
CAS :Produit contrôléFormule :C4H5N3O2SCouleur et forme :Yellow SolidMasse moléculaire :159.17Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl-ß-D-ribofuranoside
CAS :Produit contrôléFormule :C16H22O7SCouleur et forme :NeatMasse moléculaire :358.41Emtricitabine 6’-Disulfide
CAS :Produit contrôlé<p>Applications An impurity of Emtricitabine synthesis.<br></p>Formule :C16H18F2N6O4S4Couleur et forme :NeatMasse moléculaire :524.609(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate
CAS :Produit contrôléFormule :C14H24O4SCouleur et forme :NeatMasse moléculaire :288.404-Dehydroxy-4-chloro Penciclovir
CAS :Produit contrôléFormule :C10H14ClN5O2Couleur et forme :NeatMasse moléculaire :271.7N-Biotinyl Dopamine
CAS :Produit contrôlé<p>Applications Dopamine labeled biotin (LB) was used as a bifunctional compound to mediate the oxidation of β-nicotinamide adenine dinucleotide (NADH).<br>References Anderson, L., et al.: Clin. Microbiol., 19, 934 (1984), Bayer, E., et al.: Anal. Biochem., 161, 262 (1987), Harmon, F., et al.: J. Biol. Chem., 255, 9458 (1980),<br></p>Formule :C18H25N3O4SCouleur et forme :NeatMasse moléculaire :379.475’-O-Benzoyl Ribavirin
CAS :Produit contrôlé<p>Applications 5’-O-Benzoyl Ribavirin is an impurity of Ribavirin (R414475). Ribavirin impurity E.<br>References Zakharieva., et al.: Bioorganic. Medicinal. Chem., 1994, 4, 2831 (1994), Reichard., et al.: The Lancet, 351, 83 (1998),<br></p>Formule :C15H16N4O6Couleur et forme :NeatMasse moléculaire :348.315-Methylcytidine
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.<br>References Kammerer, B., et al.: Anal. Biol. Chem., 382, 1017 (2005); Strong, L. and Matsunaga, H.: J. Surg. Oncol., 4, 528 (1972)<br></p>Formule :C10H15N3O5Couleur et forme :NeatMasse moléculaire :257.243-Deaza Adenosine
CAS :Produit contrôlé<p>Applications Possesses antiviral activity. It is an inhibitor of leukocyte adhesion to TNF-treated endothelial cells.<br>References Jurgensen, C.H., et al.: J. Immunol., 144, 653 (1990), Flexner, C.W., et al.: Lancet, 339, 438 (1992), Reddy, M., et al.: Prot. Sci., 17 2134 (2008),<br></p>Formule :C11H14N4O4Couleur et forme :NeatMasse moléculaire :266.256-Chloro Didesacetyl Famciclovir
CAS :Produit contrôléFormule :C10H14ClN5O2Couleur et forme :NeatMasse moléculaire :271.709-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine
CAS :Produit contrôlé<p>Impurity Ganciclovir EP Impurity A<br>Applications 9-[[2-chloroprop-2-en-1-yl)oxy]methyl]guanine (Ganciclovir EP Impurity A) is an impurity of Ganciclovir (G235000).<br></p>Formule :C9H10ClN5O2Couleur et forme :NeatMasse moléculaire :255.66Ent-a-C Dapagliflozin (Dapagliflozin Impurity)
CAS :<p>Impurity Dapagliflozin Impurity<br>Applications Ent-α-C Dapagliflozin is an enantiomer of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formule :C21H25ClO6Couleur et forme :NeatMasse moléculaire :408.87N-Acetyl-di-O-acetyl Ganciclovir
CAS :Produit contrôlé<p>Applications Ganciclovir derivative.<br></p>Formule :C15H19N5O7Couleur et forme :NeatMasse moléculaire :381.344-Hydroxy-2-oxo-1-pyrrolidineacetic Acid Methyl Ester
CAS :Produit contrôléFormule :C7H11NO4Couleur et forme :NeatMasse moléculaire :173.17O,O',N-Tripropanal Ganciclovir
CAS :Produit contrôléFormule :C18H25N5O7Couleur et forme :NeatMasse moléculaire :423.425-Methyluridine-d4
CAS :Produit contrôlé<p>Applications Labelled 5-Methyl Uridine. A primary degradation product of tRNA, an urinary nucleoside as biological marker for patients with colorectal cancer.<br>References Borek, E., et al.: Cancer Res., 37, 3362 (1977), Sander, G., et al.: Clin. Sci.,71, 367 (1986), Sander, G., et al.: Ann. Nutr. Metab., 30, 137 (1986), Rasmuson, T., et al.: Acta Oncol., 34, 61 (1995),<br></p>Formule :C102H4H10N2O6Couleur et forme :NeatMasse moléculaire :262.252-Deoxy-3,5-di-O-p-toluoyl-a-L-ribofuranosyl Chloride
CAS :<p>Stability Moisture Sensitive, Unstable in Solution<br>Applications 2-Deoxy-3,5-di-O-p-toluoyl-α-L-ribofuranosyl Chloride (cas# 141846-57-3) is a compound useful in organic synthesis.<br></p>Formule :C21H21ClO5Couleur et forme :NeatMasse moléculaire :388.842-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 1-Methanesulfonate
CAS :Produit contrôlé<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Formule :C20H18F2O8SCouleur et forme :Off-White To Light YellowMasse moléculaire :456.41Bis(4-nitrophenyl)phosphoric Acid
CAS :Produit contrôlé<p>Applications Inhibitor of enzyme. It is used for Phosphodiesterase Substrate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Preuss, C.V., Biochem. Pharmacol., 51, 1661 (1996),<br></p>Formule :C12H9N2O8PCouleur et forme :NeatMasse moléculaire :340.182’-Epi-Lamivudine
CAS :Produit contrôlé<p>Impurity Lamivudine EP Impurity B<br>Applications 2’-Epi-Lamivudine (Lamivudine EP Impurity B) is an epimer of Lamivudine (L172500); an antiviral that inhibits HIV-reverse transcriptase.<br>References Lin, T. et al.: J. Med. Chem., 39, 1757 (1996); Schinazi, R.F. et al.: Antimicrob. Agents Chemother.,36, 672 (1992);<br></p>Formule :C8H11N3O3SCouleur et forme :Light Yellow SolidMasse moléculaire :229.266-Chloro Desacetyl Famciclovir
Produit contrôlé<p>Impurity Penciclovir Impurity F<br>Applications 6-Chloro Desacetyl Famciclovir is a prodrug of Penciclovir (P221500); an antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992); McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992)<br></p>Formule :C12H16ClN5O3Couleur et forme :NeatMasse moléculaire :313.74Folic Acid Dihydrate
CAS :<p>Applications Folic acid dihydrate<br></p>Formule :C19H19N7O6·2(H2O)Couleur et forme :Dark YellowMasse moléculaire :441.40 + 2(18.02)2,5,6-Triamino-4(3H)-pyrimidinone Sulfate
CAS :<p>Applications 2,5,6-Triamino-4(3H)-pyrimidinone Sulfate is used in the preparation of guanines and other purine derivatives with antiviral activities.<br>References Hemmati, S. et al.: Int. J. Chem. Sci., 2, 9 (2004); Chetsanga, C.J. et al.: Chem.-Biol. inter., 58, 117 (1986);<br></p>Formule :C4H7N5O·H2O·H2O4SCouleur et forme :Light Yellow SolidMasse moléculaire :257.222-Amino-5-nitroso-4,6-pyrimidinediol
CAS :Produit contrôléFormule :C4H4N4O3Couleur et forme :NeatMasse moléculaire :156.1β-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS :Produit contrôléFormule :C22H18Cl2N4O6Couleur et forme :NeatMasse moléculaire :505.3083’-Epi Gemcitabine
CAS :<p>Applications An impurity from the synthesis of Gemcitabine.<br>References Haufman, et al.: Science, 145, 585 (1964), Prusoff, et al.: Biochim. Biophys. Acta, 32, 295 (1959)<br></p>Formule :C9H11F2N3O4Couleur et forme :NeatMasse moléculaire :263.203-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS :Produit contrôlé<p>Applications 3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is an impurity of Zidovudine (A825000). Zidovudine is an antiviral agent used in the clinical treatment of HIV infections.<br>References Radatus, B.K., Org. Process. Res. Dev., 15, 1281 (2011)<br></p>Formule :C10H13N5O4Couleur et forme :NeatMasse moléculaire :267.24Zanamivir Azide Methyl Ester
CAS :Produit contrôlé<p>Applications An intermediate used in the preparation of Zanamivir derivatives.<br>References Andrews, D., et al.: Eur. J. Med. Chem., 34, 563 (1999), Altamore, T., et al.: Bioorg. Med. Chem., 14, 1126 (2006),<br></p>Formule :C12H18N4O7Couleur et forme :NeatMasse moléculaire :330.29Triphenylmethanol
CAS :<p>Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.</p>Formule :C19H16ODegré de pureté :Min. 95%Couleur et forme :White Beige Slightly Yellow PowderMasse moléculaire :260.33 g/mol5'-Epi lamivudine
CAS :<p>Lamivudine epimer</p>Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/molValacyclovir Related Compound D
CAS :<p>Valacyclovir Related Compound D is a synthetic metabolite of Valacyclovir. It is the primary metabolite of Valacyclovir, which has been shown to inhibit the activity of bacterial DNA polymerase. Valacyclovir Related Compound D is an impurity standard for valacyclovir and can be synthesized in quantities as per customer requirement.</p>Formule :C15H24N6O4Degré de pureté :Min. 95%Masse moléculaire :352.39 g/molPyrrolo[1,2-f][1,2,4]triazin-4-amine
CAS :<p>Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.</p>Formule :C6H6N4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :134.14 g/molRemdesivir impurity 9
CAS :<p>CAS No.: 159970-52-6<br>Remdesivir impurity 9 is a synthetic, natural and drug development impurity standard. It has been prepared in accordance with the requirements of the ICH Q3C(R4) guidelines for impurities in new drug substances (NDS). Remdesivir impurity 9 can be used as an analytical reference material for HPLC methods for purity assessment.<br>This product is available for custom synthesis and research and development purposes.</p>Formule :C27H35N6O8PDegré de pureté :Min. 95%Masse moléculaire :602.58 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose
CAS :<p>1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose is a natural product. It is an API impurity that has been synthesized by the custom synthesis process. 1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose has been shown to have pharmacological activity in research and development studies and as a potential drug product.</p>Formule :C21H25ClO7Degré de pureté :Min. 95%Masse moléculaire :424.87 g/molRemdesivir related compound 7
CAS :<p>Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.</p>Formule :C15H17N5O4Degré de pureté :Min. 95%Masse moléculaire :331.33 g/mol2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine
<p>2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is an analytical standard that is used in research and development of drugs. This compound has been designated as an impurity in a drug product. It has also been used as a reference standard for HPLC analysis. 2'-Deoxy-5,6-didehydro-2',2'-difluoro-6-hydroxyuridine is a metabolite of the drug product. This compound is not found in nature and has been synthesized artificially.</p>Formule :C9H12F2N2O6Degré de pureté :Min. 95%Masse moléculaire :282.2 g/molRemdesivir related compound 5
CAS :<p>Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molent-Lamivudine
CAS :<p>Enantiomer of Lamivudine</p>Formule :C8H11N3O3SDegré de pureté :Min. 95%Masse moléculaire :229.26 g/molEmpagliflozin tetraacetate
CAS :<p>Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.</p>Formule :C27H29ClO10Degré de pureté :Min. 95%Masse moléculaire :548.97 g/molRemdesivir impurity 14
<p>Remdesivir impurity 14 is a research and development product that belongs to the class of drugs. It is a synthetic metabolite with high purity. Remdesivir impurity 14 meets the pharmacopoeia standard for drug products and drug development. It has been synthesized to be used as an analytical standard for HPLC analysis of remdesivir. This product also has niche applications in metabolism studies, because it is a natural metabolite with its own metabolic pathway.</p>Formule :C18H18N5O7PDegré de pureté :Min. 95%Masse moléculaire :447.34 g/molRemdesivir impurity 3 HCl
CAS :<p>Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0</p>Formule :C9H19NO2·HClDegré de pureté :Min. 95%Masse moléculaire :209.71 g/molRemdesivir impurity 5
CAS :<p>Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.</p>Formule :C21H27N2O7PDegré de pureté :Min. 95%Masse moléculaire :450.42 g/molSofosbuvir impurity 6
CAS :<p>Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.</p>Formule :C31H27N3O7Degré de pureté :Min. 95%Masse moléculaire :553.56 g/molLamivudine acid
CAS :<p>Lamivudine acid is a synthetic orotate prodrug that is converted to the active form, lamivudine. It inhibits the synthesis of viral DNA by inhibiting the reverse transcriptase enzyme and has been used as a treatment for HIV infection. Lamivudine acid is soluble in organic solvents such as acetone and cyclohexane. The crystal structure of this compound has been determined using X-ray crystallography and exhibits a zwitterion structure with a hydrogen bond between the carboxylate group and the amide nitrogen atom of the molecule.</p>Formule :C8H9N3O4SDegré de pureté :Min. 95%Masse moléculaire :243.24 g/mol2',3'-Isopropylidene ribavirin
CAS :<p>Intermediate in the synthesis of ribavirin</p>Formule :C11H16N4O5Degré de pureté :Min. 95%Masse moléculaire :284.27 g/mol1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine
CAS :<p>1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine is a DNA methylation inhibitor that is used to treat cancer. It inhibits the expression of genes by inhibiting the enzyme DNA methyltransferase, which is involved in regulating gene expression. 1-(2-Deoxy-a-D-ribofuranosyl)-5-azacytosine has been shown to be effective against squamous cell carcinoma cells and has significant cytotoxicity against these cancer cells. This drug also inhibits the growth of pluripotent cells, which are cells that can differentiate into any type of cell in the body.</p>Formule :C8H12N4O4Degré de pureté :Min. 95%Masse moléculaire :228.21 g/molRemdesivir impurity 1
CAS :<p>Remdesivir impurity 1 is a drug product, analytical and Metabolism studies. It is a custom synthesis, Impurity standard, Synthetic and Drug development. Remdesivir impurity 1 is an API impurity that is a natural and has CAS No. 1355049-95-4. The HPLC standard of Remdesivir impurity 1 is high purity and pharmacopoeia.</p>Formule :C12H13N5O4Degré de pureté :Min. 95%Masse moléculaire :291.26 g/mol4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
CAS :<p>4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one (4AAT) is an analytical chemical that is used for research and development purposes. 4AAT is a metabolite of the antibiotic ampicillin and has been identified as an impurity in the drug product. It can be synthesized from 2-(4'-chlorophenyl)benzaldehyde, 3,5'-di-O-(4'-chlorobenzoyl)-2',3'-dideoxyribose and sodium azide in a two step process with 98% purity. 4AATs are also found to be present in natural products such as honey or sugar cane juice.</p>Formule :C22H18Cl2N4O6Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :505.31 g/mol1-(2-Deoxy-β-D-xylofuranosyl)-5-methyluracil
CAS :<p>1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.</p>Formule :C10H14N2O5Degré de pureté :Min. 95%Masse moléculaire :242.23 g/mol
![(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM219050.webp&w=3840&q=75)
![9-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC379785.webp&w=3840&q=75)
![Pyrrolo[1,2-f][1,2,4]triazin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FFP55646.webp&w=3840&q=75)
![1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIC181108.webp&w=3840&q=75)
![4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIA74824.webp&w=3840&q=75)
