Étalons de l'industrie alimentaire

<p>Applications A substituted piperidine as pesticide.<br>References Nishizawa, R., et al.: Bioorg. Med. Chem. Lett., 20, 763 (2010), Liras, S., et al.: Bioorg. Med. Chem. Lett., 20, 503 (2010),<br></p>

<p>Applications Arachidic acid is a saturated fatty acid and a minor constituent of peanut oil, coconut oil and corn oil. Arachidic acid is used for the production of detergents, photographic materials and lubricants.<br>References Kumar, S. R., et al.: J Chemtracks., 13, 277 (2011); Poyarkova, T.N., et al: J. App. Chem. 85, 1259 (2012);<br></p>

<p>Applications 2,2-Dimethyloctanoic Acid is used in biological studies as benzyl dimethyloctanoate metabolite of sewage bacteria.<br>References Millier, A., et al.: Bull. Environ. Contam. Toxicol., 28, 113 (1982);<br></p>

<p>Stability Hygroscopic<br>Applications 6-(L-1,2,3-Trihydroxybutyl)-pterin (cas# 13392-24-0) is a useful research chemical.<br></p>

<p>Applications Propiophenone-d10 (CAS# 288400-96-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications A derivative of Resveratrol which shows apoptotic activity at nanomolar concentrations. Has an IC50= 0.3. It showed activity toward resistant HL60R cells and their activity was higher than that of several classic chemotherapeutic agents.<br>References Roberti, M., et al.: J. Med. Chem., 46, 3546 (2003)<br></p>

<p>Applications Ethyl Octadecanoate-d35 (CAS# 1219795-49-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Dimethyl Terephthalate-2,3,5,6-d4 (CAS# 74079-01-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Dimethyl 3-Hydroxyphthalate is used as a reactant in the synthesis of proteolysis targeting chimeras.<br>References Schiedel, Matthias, et al.: J. of Med. Chem., 61(2), 482-491 (2018); Lebraud, Honorine, et al.: ACS Cent. Sci., 2(12), 927-934 (2016);<br></p>

<p>Applications n-Heneicosane-d44 (CAS# 39756-37-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2,2-Dimethoxy-2-phenylacetophenone (cas# 24650-42-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Methoxynaphthalene-1,3,4,5,6,7,8-d7 (CAS# 1219795-25-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications A chloropropanol which shows toxic effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andersen, H., et al.: Toxicology, 136, 67 (1999), Fry, J., et al.: Food Chem. Toxicol., 37, 351 (1999), Garle, M., et al.: Xenobiotica, 29, 533 (1999),<br></p>

<p>Applications DL-Phenylalanine-2-d1 (CAS# 14246-24-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications L-4-Hydroxyphenyl-d4-alanine-2-d1 (CAS# 1226919-57-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications S-Rivastigmine is an isomer of Rivastigmine ( an acetylcholinesterase inhibitor used in the treatment of neurological disorders such as Alzheimer’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Howes, L et al.: Drug. Safe., 37, 391 (2014); Shahar, O. et al.: Nucl. Acids Res., 42, 5869 (2014);<br></p>

<p>Applications Triacontanoic Acid has agricultural applications and is a useful compound in the removal of residual pesticides from fruit via ozone-microbubble treatment.<br>References Li, C., et al.: Food Control, 120, 107548 (2020)<br></p>

<p>Applications Retin-15-yl β-D-Glucopyranosiduronic Acid is a Vitamin A metabolite of blood plasma.<br>References Eckhoff, C., et al.: Toxicol. Appl. Pharm., 11, 116-27 (1991)<br></p>

<p>Applications Hexadecanoic-2,2,16,16,16-d5 Acid (CAS# 1219802-61-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Glyceryl-d5 Trioleate (CAS# 60892-83-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 6α-Naloxol is a metabolite of Naloxone (N285000), a specific opioid antagonist. Narcotic antagonist.<br>References Chatterjie, N., et al.: J. Med. Chem., 18, 490 (1975); Bilsky, E., et al.: J. Pharmacol. Exp. Ther., 277, 484 (1996); Blokhina, E., et al.: Eur. J, Pharmacol., 406, 227 (2000); Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>

<p>Applications Isotope labelled Di-n-heptyl Phthalate is a Phthalate derivative and an organic extract contaminant found in drinking water, which was shown to activate Nrf-2-Mediated Antioxidant response in human cell line.<br>References Wang, S., et al.: Environ. Sci. Technol., 47, 4768 (2013);<br></p>

<p>Applications Fenuron-d5 (phenyl-d5) (CAS# 1219802-06-8) is a useful isotopically labeled research compound. It can be used for the preparation of difunctionalized indoles.<br>References Lv, H., et al.: Org. Biomol. Chem., 15, 8054 (2017)<br></p>

<p>Applications (E)-4’-Hydroxy Tamoxifen is an active metabolite of Tamoxifen (T006000).<br>References Muerdter, T.E. et al.: Clin. Pharmacol. Therap., 89, 705 (2011);<br></p>

<p>Applications 6,6'-Methylenebis(2-(tert-butyl)-4-ethylphenol) (cas# 88-24-4) is a useful research chemical.<br></p>

<p>Applications A component of garlic which revealed antiplatelet, antithrombotic activity and reduced LDL oxidation thus indicating their possible use for cardiovascular disease.<br>References Steinberg, D., et al.: J. Biol. Chem., 272, 20963 (1997), Lawson, L., et al.: J. Agric. Food Chem., 53, 6254 (2005), Gonen, A., et al.: Pathobiology, 72, 325 (2005),<br></p>

<p>Applications n-Dodecyl Alcohol-OD (CAS# 14848-65-8) is a useful isotopically labeled research compound. It can be used for neutron spin-echo spectroscopy.<br>References Yamaguchi, T., et.al., J. Phy. Chem. B., 123, 239-246, (2019);<br></p>

<p>Applications 1,3-Diethyl-2-thiourea (cas# 105-55-5) is a useful research chemical.<br></p>

<p>Stability Store in Freezer<br>Applications Inhibits β-galactosidase enzyme.<br>References Biosci. Biotechnol. Biochem., 57(1), 107 (1993)<br></p>

<p>Applications 1,3,6,8-Tetrachlorobenzo-p-dioxin is an intermediate in the synthesis of 1,2,3,6,7,8-Hexachlorodibenzodioxin which is a toxic polychlorinated dibenzo-p-dioxin detected in domestic meat and poultry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feil, V., et al.: J. Agric. Food Chem., 48, 6163 (2000), Huwe, J., et al.: Food Addit. Contam., 21, 182 (2004), Llobet, J., et al.: Toxicol. Lett., 178, 117 (2008),<br></p>

<p>Applications 3-(Methyl-d3-nitrosoamino)propionitrile (CAS# 1329834-39-0) is a useful isotopically labeled research compound.<br></p>

<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Most important of the provitamins A. Widely distributed in the plant and animal kingdom. In plants it occurs almost always together with chlorophyll. Vitamin A precursor. Ultraviolet screen.<br>References Karrer, et al.: Helv. Chim. Acta, 12, 1142 (1929), Fischli, M., et al.: Helv. Chim. Acta, 58, 1584 (1975), Desmet, J., et al.: Biochem. Biophys. Acta, 912, 211 (1987), Tan, C., et al.: Food Chem., 92, 661 (2005), Chu, B., et al.: J. Agric. Food Chem., 55, 6754 (2007),<br></p>

<p>Applications A metabolite of Nefazodone (N389100), a novel antidepressant.<br>References Myol, R., et al.: Clin. Pharmacol. Ther., 37, 210 (1985), Haria, M., et al.: Drugs Aging, 4, 331 (1994), Kalgutkar, A., et al.: Drug Metab. Dispos., 33 243 (2005),<br></p>

<p>Applications Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986). Withaferin A has recently been found to be a leptin sensitizer that can reduce the weight in obese mice fed in a high-fat diet (see C249500).<br>References Shohat, B., et al.: Cancer Chemother. Rep., 51, 271 (1967), Shohat, B., et al.: Int. J. Cancer., 8, 487 (1971); Chem. and Eng. News p. 6, Aug. 8, 2016<br></p>

<p>Stability Hygroscopic<br>Applications Isotope labelled Diglycolic Acid (D446330), is a known metabolite of Diethylene Glycol (D444285), which acts as a nephrotoxic agent in human proximal renal tubule cells. Diglycolic Acid is also used in the synthesis of N-interlinked imipramines which show apoptotic activity against malignant cells as well as signs of combatting Burkitt’s lymphoma.<br>References Landry, G. et al.: Toxicol. Sci., 124, 35 (2011); Besenhofer, L. et al.: Toxicol. Sci., 123, 374 (2011); Bright, S. et al.: Bioorg. Med. Chem. Lett., 23, 1220 (2013);<br></p>

<p>Applications Dibutyl Carbonate is a potential fuel substitute due to the observed decrease in CO2 emissions. Also used in CO2 catalytic activation.<br>References Hellier, P. et al.: Energy Fuel, 27, 5222 (2013); Shang, J. et al.: Green Che,., 14, 2899 (2012);<br></p>

<p>Applications Tricosanoic Acid is a saturated fatty acid. It may be used to activate orphan G protein-coupled receptor GPR40.<br>References Briscoe, C., et al.: J. Biol. Chem., 278, 11303 (2003)<br></p>

<p>Applications Fluridone, is a new herbicide for aquatic plants, such as Curlyleaf pondweed (Potamogeton crispus) in lakes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Johnson, J., et al.: Lake and Reservoir Management, 28, 346 (2012)<br></p>

<p>Applications It was selected as a major hydroxylated polychlorinated biphenyl metabolite detected from serum of wildlife and humans and was examined for its effect on the level of serum thyroid hormone in mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barter, R., et al.: Toxicol. Appl. Pharmacol., 128, 9 (1994), Hallgren, S., et al.: Arch. Toxicol., 75, 200 (2001), Craft, E., et al.: Toxicol. Sci., 68, 372 (2002), Kato, Y., et al.: Toxicol. Sci., 81, 309 (2004), Kato, Y., et al.: Drug Metab. Dispos., 35, 1949 (2007),<br></p>

<p>Applications A nitrosoamine compound that shows carcinogenic effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Scanlan, R., et al.: Cancer Res., 43, 2435 (1983), Spiegelhalder, B., et al.: Carcinogenesis, 4, 1147 (1983), Lijinsky, W., et al.: Mutat. Res., 443, 129 (1999), Robichova, S., et al.: Chem. Biol. Interact., 148, 163 (2004),<br></p>

<p>Applications Butyl Benzoate has a fruity aroma an is commonly employed in food additives and flavorings. Butyl Benzoate is also a useful reagent in synthesis.<br>References Mkhonazi, B., et al.: Molecules., 25, 1040 (2020); Rottiers, H., et al.: Eur. Food Res. Technol., 245, 2459-2478 (2019)<br></p>

<p>Applications Substrate specificity of haloalkane dehalogenases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),<br></p>

<p>Applications 2-Acetylfuran is a widely used reagent in manufacturing pharmaceuticals and aroma compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bertero, M., et al.: Fuel, 95, 263 (2012); Dang, Q., et al.: J. Medn. Chem., 54, 153 (2011); Candu, N., et al.: Topics. Catalysis., 52, 571 (2009);<br></p>

<p>Applications Induced mutation of dodecanedioic acid producing Candida tropicalis. Used in cosmetic compositions.<br>References Ardawi, M., et al.: Biochem. J., 212, 835 ( 1983), Renner, F., et al.: J. Lipid Res., 27, 72 (1986), Gu, H., et al.: Anal. Chem., 79, 89 (2007),<br></p>

<p>Applications Isotope labelled Diundecyl Phthalate is a phthalate diester and has been investigated for its toxicology in male rats for risk assessment.<br>References Kwack, S.J., et al.: J. Toxicol. Environ. Health., 72, 1446 (2009); Serafimova, R., et al.: Chem. Res. Toxiciol., 20, 662 (2007);<br></p>

<p>Applications Ethyl nonanoate (CAS# 123-29-5) is a useful research chemical compound.<br></p>

<p>Applications Labelled analogue of Di-n-propyl Phthalate, a phthalate metabolite of Di-n-butyl phthalate (D429495) degradation with potential genotoxic effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fromme, H. et al.: Environ. Int., 37, 715 (2011); Cao, X.-L.: Comp. Rev. Food Sci. Food Safety, 9, 21 (2010); Begum, A. et al.: Chem. Lett., 33, 682 (2004);<br></p>

<p>Applications Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice.<br>References Lin, C. C., et al.: Cancer Lett., 168, 125 (2001)<br></p>

<p>Applications 5-Ethyl-4-hydroxy-2-methyl-3(2H)-furanone, mixture of isomers 96%, FG (cas# 27538-09-6) is a useful research chemical.<br></p>

<p>Applications Hexacosanoic Acid (cas# 506-46-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methylimidazole-d6 (CAS# 1173022-19-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Butyrophenone-2',3',4',5',6'-d5 (CAS# 39058-44-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Vitamin D5 is used in the synthetic preparation of 1α-Hydroxyvitamin D5 a promising chemopreventive agent for breast cancer.<br>References Moriarty, R.M., Albinescu, D.: J. Org. Chem., 70, 7624 (2005)<br></p>

<p>Applications Methyl Octadecanoate-d35 (CAS# 29823-25-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Methoxy-d3-benzaldehyde (CAS# 1219795-07-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,​9-​Decadiene is used in acyclic diene metathesis copolymerization (ADMET) along with 1, 5-hexadiene to form polybutadiene –polyoctenamer copolymers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wagener, K.B., et al.: Macromolecules, 23, 5155-57 (1990);<br></p>

<p>Applications Dimethyl phthalate-3,4,5,6-d4<br></p>