APIs pour la recherche et les impuretés

N,N-Dimethyl-3-(4-methylbenzoyl)propionamide is a metabolite of the antihistamine drug diphenhydramine. It is a natural impurity and an impurity standard for this drug. N,N-Dimethyl-3-(4-methylbenzoyl)propionamide can be used in pharmacopoeia to test for purity and quality of drugs, as well as for analytical purposes. It has also been used in drug development and metabolism studies.

N-[5-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-3-yl]-2,3-dichlorobenzamide is a pharmaceutical dosage form that is titrated to achieve the desired therapeutic effect. It is used to treat epilepsy and bipolar disorder. Lamotrigine binds to sodium channels in nerve cells and blocks their opening. This prevents the influx of sodium ions that are necessary for neuronal transmission. Lamotrigine has been shown to have an anticonvulsant effect by reducing the frequency of seizures in patients with epilepsy.

Cetirizine metabolite

(betaS,deltaS)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole- 1-heptanoic acid calcium salt (2:1) is a fluorinated derivative of the natural metabolite 2-(4-fluorophenyl)-beta,delta-dihydroxy -5-(1 methylethyl)-3 phenyl 4-[(phenylamino)carbonyl]-1H pyrrole 1 heptanoic acid. It is an enantiomer of the racemate with optical purity > 98%. The compound has been used as a pharmacological and supramolecular chemistry probe for assays and chemosensors.

2-Hydroxy-2-{4-[2-(hydroxyethoxy)ethyl]piperazin-1-yl}dithiazepin (LPSE) is a monoclonal antibody that is used in the diagnosis of atrial fibrillation. It binds to the antigenic determinant on the surface of atrial cells and also has high affinity for cardiac troponin I. LPSE has biochemical properties that distinguish it from other antibodies and is not known to have any adverse reactions or interactions with other drugs. The clinical relevance of LPSE has been demonstrated by its ability to detect atrial cells in tissue samples from patients with atrial fibrillation, and to discriminate between samples taken from patients who had undergone catheter ablation or those who had not undergone this procedure. LPSE binds to tetroxide, gamma-aminobutyric acid (GABA), amides, and proteins, as well as hl-60 cells,

Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.

N-(((5S)-3-(4-(4-Morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide is an impurity of the antibiotic linezolid. It is a contaminant that can be found in urine and blood samples. N-(((5S)-3-(4-(4-Morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide has been shown to be amyloidogenic, meaning it can form plaques in the brain and lead to Alzheimer's disease.

The compound is a natural product and its structure is similar to that of the neurotransmitter dopamine. The compound has been used in pharmacological studies as a tool for understanding the neurotoxicity of dopamine and other drugs. This drug has also been used to investigate the level of dopamine receptor occupancy by various dopaminergic drugs.

Analogue of sildenafil

Tirzepatide impurity

Nisoxetine is a norepinephrine (NE) reuptake inhibitor that is used as an antidepressant. It has been shown to be a potent and selective NE reuptake inhibitor with a high affinity towards the NE transporter in rat brain synaptosomes, with potency several times higher than that of tricyclic antidepressants. Nisoxetine's major advantage over other antidepressants is its high efficiency, which makes it suitable for large-scale production. The synthesis of nisoxetine involves two steps: 1) reaction of 3-[methyl(phenylmethyl)amino]-1-phenyl-1-propanone hydrochloride with toluene to form the corresponding methyl ester and 2) hydrogenation of the methyl ester to form nisoxetine. This synthesis is efficient, stable, and chiral due to the use of bimetallic catalysts.

4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid, ethyl ester 1,1-dioxide (4HMBC) is an organic compound that is used as a precursor in the synthesis of other chemicals. 4HMBC is used to produce xylene, sulfoxide and diethyl ether by reacting with magnesium and ethylene. It is also used in the production of dimethylformamide, a solvent that is useful for the manufacture of many products including pharmaceuticals. 4HMBC reacts with methyl iodide to form 4-(dimethylamino)pyridine which can be used for the synthesis of piroxicam. The chemical has been shown to be effective as an insecticide against ants and cockroaches. It can also be used to synthesize dyes or pigments. The chemical can be obtained by methylating 4HBC with methanol in the presence

Please enquire for more information about Defluoro atorvastatin acetonide tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-N-Butyl 3-(4-methoxy benzoyl)-benzofuran is a x-ray crystal structure of an antibacterial agent that belongs to the class of β-unsaturated ketones. It has been shown to have cardiovascular activity, and is used in the treatment of depression. The compound binds to the active methylene group on the bacterial cell wall, which prevents cross linking of peptidoglycan chains. This leads to a reduction in cell wall synthesis and increased permeability of cells, which may result in death. The 2-N-butyl 3-(4-methoxy benzoyl)-benzofuran molecule also contains two phenyl groups that are able to form hydrogen bonds with each other, as well as dihedral angles that can form hydrogen bonds with water molecules. These properties contribute to its antidepressant activity.

1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine is an analytical standard and a drug product. It is a synthetic compound that has been shown to have pharmacological effects similar to those of the analgesic or opioid drugs. 1-Benzyl-4-(5,6-dimethoxy-1-oxoindan-2-ylidene)methylpiperidine can be used as an impurity standard for HPLC analyses as well as metabolic studies. This compound is also known to have potential interactions with other drugs.

N-tert-butyl-N-(((S)-3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide (CAS 1215006-11, API impurity) is a synthetic compound from the drug development process. This impurity has been identified in the natural product and is not an active ingredient. It is found as a Metabolite in the pharmacopoeia and analytical methods. This substance is used for research and development of drugs, such as for standardizing HPLC.

1-Phenyl-1-(2-pyridinyl)methanol is an organic compound that has a reactive, functional group. It is used as a solvent in the laboratory and industry. This chemical reacts with chloride to produce 1-chloro-1-phenylmethanol. It can also be reacted with basic groups such as sodium hydroxide to produce 1-phenyl-1-(2-hydroxy pyridinium) methanol. The reaction of 1-phenyl-1-(2-pyridinyl) methanol with carbon tetrachloride produces trichlorobenzene and carbon dioxide. Impurities in this compound include inorganic acids such as hydrochloric acid and sulfuric acid, which are found at levels below 0.5%. Alcohols found in this compound include ethanolamine, which is an impurity at levels exceeding 2%.

4-(Aminomethyl)-1-cyclohexene-1-carboxylic acid is an antifibrinolytic agent that can be used to control bleeding. It is a carboxymethyl cellulose with a menthol flavour and it stabilizes the hemostatic effect of tranexamic acid. 4-(Aminomethyl)-1-cyclohexene-1-carboxylic acid has been shown to be effective in controlling bleeding in patients with disorders such as hemophilia and von Willebrand disease. The drug is stable in acidic compositions, making it useful for dental applications as well.

D-Val(10)-Semaglutide is a semaglutide impurity. The amino acid at position 10 has been replaced by the D-form of the amino acid D-valine (D-Val). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.