APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.205 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.975 produits)
- Dérivés de Quinazoline et de Quinoléine(66.222 produits)
- Quinones et Dérivés(24.379 produits)
- Sels et Dérivés d’API(92.942 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66875 produits trouvés pour "APIs pour la recherche et les impuretés"
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Sildenafil N-Oxide
CAS :Sildenafil N-Oxide is a solvate, hydrate, and prodrug of sildenafil citrate. It is used for the treatment of erectile dysfunction or pulmonary hypertension. Sildenafil N-Oxide is an oral drug that is converted to its active form, sildenafil, in the liver by CYP3A4. Sildenafil N-Oxide's effects on human erection are thought to be due to its ability to block phosphodiesterase type 5 (PDE5), which increases the levels of cGMP in smooth muscle cells and causes relaxation of the corpus cavernosum. This leads to increased blood flow into the penis and an erection.Formule :C22H30N6O5SDegré de pureté :Min. 95%Masse moléculaire :490.58 g/molRoxithromycin impurity K
Roxithromycin impurity K is a custom synthesis that is used as a research and development tool. It is not intended for use in drug products. Roxithromycin impurity K has been shown to have effects similar to those of roxithromycin, but with different metabolic pathways and properties. Roxithromycin impurity K has been shown to be metabolized through the cytochrome P450 system, which may result in the production of metabolites that are more potent than roxithromycin itself.Formule :C41H76N2O16Degré de pureté :Min. 95%Masse moléculaire :853.05 g/molLisdexamfetamine dimesylate impurity B
Lisdexamfetamine dimesylate impurity B is a high purity, synthetic, custom synthesis drug product. Lisdexamfetamine dimesylate impurity B is a metabolite of lisdexamfetamine and the impurity standard for lisdexamfetamine dimesylate. It is used in pharmacopoeia to develop drugs. Lisdexamfetamine dimesylate impurity B is also used in analytical studies such as HPLC standards.Degré de pureté :Min. 95%Daunomycinone
CAS :Daunomycinone is a chemical compound that belongs to the group of antitumor agents. It is used in cancer therapy and has been shown to inhibit protein synthesis, leading to cell death. Daunomycinone can be synthesized by reacting adriamycin with trifluoroacetic acid in the presence of an organic base. This reaction produces a daunomycinone molecule that has a hydroxyl group at one end and a carbonyl group at the other. The binding constants between daunomycinone and human serum proteins have been determined experimentally using molecular modeling techniques. Hydrogen bonding interactions are also present in this complex, which may account for its high affinity for proteins found in human serum.Formule :C21H18O8Degré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :398.36 g/molN-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2-nitro-2,2-ethendiamine, S-oxide
CAS :N-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2,2-ethendiamine, S-oxide is a chemical compound that has been shown to be an effective inhibitor of the metabolism of many drugs in rat liver microsomes. This drug is used as an analytical method in urine samples to study the clinical relevance of n-oxide metabolites and their effects on drug interactions. N-[2-[[[5(Dimethylamino)methyl]-2-furanyl]thio]ethyl]-N'-methyl-2,2-ethendiamine, S-oxide has been shown to have optimum concentration at 0.1 mM in wastewater treatment systems. The kinetic data for this compound were obtained using a model system with low bioavailability.Formule :C13H22N4O4SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :330.4 g/mol2-(4-Butylphenyl)propionic acid, racemic
CAS :2-(4-Butylphenyl)propionic acid (p-butylhydratropic acid) is a known impurity of ibuprofen (Ibuprofen impurity B) which derives from an impurity present in the isobutylbenzene starting material and 2-(4-butylphenyl)propionic acid. p-Butylhydratropic acid is therefore used as a reference analytical standard.Formule :C13H18O2Degré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :206.28 g/molDaunorubicinol
CAS :Daunorubicin metabolite
Formule :C27H31NO10Degré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :529.54 g/mol(R,S)-N-Methyl 3-benzylamino-1-phenyl-1-propanol
CAS :(R,S)-N-Methyl 3-benzylamino-1-phenyl-1-propanol is an impurity standard for the drug product (R,S)-N-methyl 3-(benzylamino)-1-phenylpropanol. It is a synthetic, analytical and HPLC standard. This compound has shown to possess pharmacopoeia standards and can be custom synthesized for your needs.Formule :C17H21NODegré de pureté :Min. 95%Couleur et forme :Slightly Yellow Clear LiquidMasse moléculaire :255.35 g/molOlmesartan dimer ester impurity
CAS :The product is an impurity that is used as a standard in HPLC analysis. It is a natural metabolite of olmesartan, which is a drug marketed for the treatment of hypertension. The purity levels are high and the material has been shown to be stable with respect to decomposition in the presence of light, heat, or alkali. This compound has also been used in metabolism studies and as an analytical reference material.
Formule :C48H50N12O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :874.99 g/molTrityl olmesartan acid
CAS :4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazol-5-caboxylic acid (4MPPC) is a water soluble, clear liquid that is used as a solvent. It can be prepared by the reaction of sodium carbonate with an organic or inorganic salt solution in acetonitrile. The solvents are then removed using filtration and the final product is obtained by evaporation of the solvent. 4MPPC has been used in the preparation of medoxomil, which is an antibiotic that inhibits bacterial growth by binding to DNA gyrase and topoisomerase IV.Formule :C43H40N6O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :688.82 g/molRemdesivir impurity 12
CAS :Remdesivir impurity 12 is a drug product that is used in research and development. It is a synthetic impurity standard for HPLC analytical methods. Remdesivir impurity 12 is an impurity of the drug, remdesivir, which has antiviral activity against HIV-1. Metabolism studies have been conducted to investigate how this impurity affects the pharmacokinetics of remdesivir. The use of synthetic material ensures high purity and quality for this product.Formule :C21H31N6O8PDegré de pureté :Min. 95%Masse moléculaire :526.48 g/mol5-(2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
CAS :5-(2-Cyclopropyl-1-(3-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate is a substance that is used as a reference in high performance liquid chromatography (HPLC) methods. It is used to validate the method in accordance with the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). The substance is also known as prasugrel hydrochloride and it is used as an antiplatelet agent.Formule :C20H20FNO3SDegré de pureté :Min. 95 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :373.44 g/molAmiodarone N-oxide HCl
CAS :Amiodarone N-oxide HCl is a class III antiarrhythmic drug that acts by slowing the heart rate and prolonging the time between heartbeats. It has been shown to be effective in treating atrial fibrillation, ventricular fibrillation, and atrial flutter. Amiodarone N-oxide HCl has significant cytotoxicity, which can lead to cardiomyopathy and myocardial infarcts. Due to its long half life, amiodarone can accumulate in the body and cause side effects such as pulmonary toxicity, gastrointestinal bleeding, thyroid dysfunction, or liver damage. It is not recommended for use in patients with structural heart disease or those taking nonsteroidal anti-inflammatory drugs (NSAIDs) because of an increased risk of adverse events.Formule :C25H29I2NO4HClDegré de pureté :Min. 95%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :697.77 g/molFeudomycinone B
CAS :Feudomycinone B is a synthetic analogue of the natural product, Feudomycin. It is a potent cytotoxic agent with a broad spectrum of activity against microorganisms, including Gram-positive and Gram-negative bacteria, mycobacteria, and fungi.Degré de pureté :Min. 95%D-Asp(9)-Tirzepatide
Tirzepatide impurity.Formule :C225H348N48O68Couleur et forme :PowderMasse moléculaire :4,813.5 g/mol3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one
CAS :3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one is a triazine derivative that is used as an analytical reagent and intermediate. It has been used as a wastewater analysis method to measure the concentration of carbamazepine. 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one has also been shown to be useful in developing analytical methods for clinical trials. 3DCTKP has also been used to test the matrix effect of carbamazepine by analyzing it in different matrices such as water and human plasma.
Formule :C9H6Cl2N4ODegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :257.08 g/mol2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol
CAS :2- (4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol is a pharmaceutical intermediate that is a potent inhibitor of the enzyme acetylcholinesterase. It has been used as a photolytic probe in chromatographic experiments. 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol has been synthesized by the reaction of 4-(benzo[b]thieno[2,3d]thiazol)piperazine with ethanol. The impurities present are quantified and their concentrations are reported as percent weight/volume (% w/v). Impurities that may be found in this product include acetonitrile, orthophosphate, and linearity.Formule :C19H21N3OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :339.46 g/molD-Ala(24)-Semaglutide
D-Ala(24)-Semaglutide is a semaglutide impurity. The amino acid at position 24 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molSemaglutide Impurity 54 (D-Ala 18)
D-Ala(18)-Semaglutide is a semaglutide impurity. The amino acid at position 18 has been replaced by the D-form of the amino acid D-alanine (D-Ala). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/mol
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