APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.203 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.974 produits)
- Dérivés de Quinazoline et de Quinoléine(66.217 produits)
- Quinones et Dérivés(24.378 produits)
- Sels et Dérivés d’API(92.894 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66870 produits trouvés pour "APIs pour la recherche et les impuretés"
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N-Acetyldesloratadine
CAS :N-Acetyldesloratadine is a second generation antihistamine that has high affinity for histamine H1 receptors. It is an orally active drug that is used to treat allergic rhinitis, chronic idiopathic urticaria, and pruritus. N-Acetyldesloratadine has been shown to inhibit platelet aggregation in vitro and in vivo. This activity may be due to the drug's ability to bind with high affinity to histamine receptor sites on the membranes of platelets, thereby inhibiting the binding of adenosine diphosphate (ADP) to its receptor site. N-Acetyldesloratadine also inhibits the release of serotonin from mast cells and basophils in vitro.Formule :C21H21ClN2ODegré de pureté :Min. 95%Masse moléculaire :352.9 g/mol2,3-Dichlorobenzoic acid
CAS :2,3-Dichlorobenzoic acid is an organic compound that belongs to the class of carboxylates. It is used as a drug substance in the treatment of mycobacterial infections. 2,3-Dichlorobenzoic acid has been shown to have antimicrobial activity against Mycobacterium tuberculosis and other mycobacteria. The sensitivity index for this compound was determined using a chromatographic method with human erythrocytes as the test organism. 2,3-Dichlorobenzoic acid displays its antibacterial activity by inhibiting protein synthesis and cell division. This drug also forms crystalline solids that are soluble in organic solvents such as chloroform or benzene.Formule :C7H4Cl2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :191.01 g/mol4-(2-Methoxyethyl)phenol
CAS :4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.
Formule :C9H12O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :152.19 g/molPhytofluene
CAS :Phytofluene is a natural compound that has been found to have potential as an anticancer agent. It acts as an inhibitor of cancer cell growth and induces apoptosis, or programmed cell death, in tumor cells. Phytofluene has been shown to inhibit the activity of several important proteins involved in cancer development, including chitinase and heparin-binding protein. It is derived from Chinese medicinal plants and has been used for centuries for its anti-inflammatory and antioxidant properties. In addition to its anticancer effects, phytofluene has also been found to inhibit the activity of kinases in human urine, suggesting a potential role in the treatment of other diseases such as diabetes and cardiovascular disease.Formule :C40H62Degré de pureté :Min. 95%Masse moléculaire :542.9 g/molN-Desmethyl cyamemazine maleate
CAS :Cyamemazine is an antipsychotic drug that has been used for the treatment of schizophrenia and other psychotic disorders. N-Desmethyl cyamemazine maleate, a metabolite of cyamemazine, has been shown to have neuroprotective effects in vitro.Formule :C18H19N3S·C4H4O4Degré de pureté :Min. 95%Masse moléculaire :425.5 g/molO-Methyl atorvastatin calcium
CAS :O-Methyl atorvastatin calcium is a drug product that is an HPLC standard. It is a natural metabolite of atorvastatin, which is synthesized by cytochrome P450 3A4 in the liver. O-Methyl atorvastatin calcium has been shown to be an impurity in some batches of atorvastatin calcium. It has been observed to have pharmacological effects similar to those of atorvastatin. O-Methyl atorvastatin calcium has been used as a research and development (R&D) tool for studies on the metabolism of drugs, including its own synthesis and the study of the effect on other drugs such as amiodarone.Formule :CaC68H71F2N4O10Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,182.39 g/molBis-[[2-aminoethyl]thio]methane
CAS :Bis-[[2-aminoethyl]thio]methane is a custom synthesis, drug product, niche, Metabolite, Drug development, Natural, pharmacopoeia and API impurity. This chemical is CAS No. 22907-27-3 and has the molecular weight of 249.00 g/mol. It can be synthesized in the laboratory using the following methods: HPLC standard, Research and Development and Impurity standard. The chemical is an analytical standard with a purity of 99%. This chemical can be used as analytical reagent or in research and development of drugs.Formule :C5H14N2S2Degré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :166.31 g/mol(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
CAS :(R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one (FPH) is a synthetic drug product that is used as an impurity standard in the synthesis of pharmaceuticals. It is also used in metabolism studies and research and development. FPH has been shown to be a metabolite of the drug product, 3-(3-fluoro-4-(4-morpholinyl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one, which is classified as an API impurity for pharmacopoeia purposes. FPH has a molecular formula of C11H14FO2N2O and a molecular weight of 222.26 g/mol. The CAS number for FPH is 168828-82-8.Formule :C14H17FN2O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :296.29 g/molOmeprazole impurity F and G
CAS :Omeprazole is a proton pump inhibitor that inhibits the H+/K+-ATPase enzyme in gastric parietal cells. Omeprazole impurity F and G are metabolites of omeprazole. Omeprazole impurity F is a metabolite of omeprazole that forms by oxidation of the methylthio group in omeprazole to form a sulfoxide. Omeprazole impurity G is formed by hydrolysis of the methylthio group in omeprazole to form an alcohol. The purity of this product is high and can be custom synthesized based on customer's needs. It is also available as an HPLC standard or as an API impurity for use in metabolism studies.Formule :C16H13N3O2SDegré de pureté :Min. 95%Couleur et forme :Red PowderMasse moléculaire :311.36 g/mol4-Amino-2-chloro-6,7-dimethoxyquinazoline
CAS :4-Amino-2-chloro-6,7-dimethoxyquinazoline (4ACDMQ) is a synthetic compound that has been used as a chemical intermediate. The chemical structure of 4ACDMQ is similar to that of the natural amino acid tryptophan. It is synthesized by reacting phosphorus pentachloride with 2,6,7-trimethoxyquinazoline in the presence of hydroxide solution and hexamethylphosphoramide. 4ACDMQ has been shown to be an inhibitor of ubiquitin proteasome system and has been used in functional studies on this system. The reaction yield for 4ACDMQ can be increased by using sodium hydroxide solution or n-dimethyl formamide as a solvent. Functional assays have shown binding properties for 4ACDMQ to proteins such as ubiquitin and proteasome subunits.Formule :C10H10ClN3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :239.66 g/molN-Nitroso-N-methyl-4-aminobutyric acid
CAS :N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a solid with a low melting point which has been identified as a potentially carcinogenic component of both tobacco and tobacco smoke. NMBA is also one of a number of nitrosamine impurities which have been found to be present in angiotensin II receptor blocker (ARB) drugs used to treat high blood pressure.
Formule :C5H10N2O3Degré de pureté :Min. 98 Area-%Couleur et forme :Slightly Yellow PowderMasse moléculaire :146.14 g/molN-Methylnitroacetamide
CAS :N-Methylnitroacetamide is a pyridinium salt used as an additive in pharmaceutical preparations. It is also a drug substance that is used for oral dosage, and has been shown to be active in methylene chloride and organic solvents. This chemical has been found to have a number of impurities, including acidic compounds and organic solvents, which can cause it to degrade over time. The use of this compound requires validation and kinetic studies to ensure it meets the quality standards for its intended use.Formule :C3H6N2O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :118.09 g/molRiboflavin EP Impurity C
CAS :Riboflavin EP Impurity C is a synthetic compound that is used as an impurity standard in the manufacture of Riboflavin-5'-Phosphate. Riboflavin EP Impurity C is also a metabolite that can be found in human urine, and is used to study metabolism.Formule :C13H18N4O6Degré de pureté :90%MinCouleur et forme :PowderMasse moléculaire :326.31 g/molSemaglutide Impurity 60 (D-Arg 30)
D-Arg(30)-Semaglutide is a semaglutide impurity. The amino acid at position 30 has been replaced by the D-form of the amino acid D-arginine (D-Arg). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molCetirizine impurity B dihydrochloride
CAS :Cetirizine impurity B dihydrochloride is a minor impurity of cetirizine, which is a non-sedating antihistamine. The purity of the compound was determined by high performance liquid chromatography (HPLC) and its bioequivalence to cetirizine was assessed in a population pharmacokinetic study. Cetirizine impurity B dihydrochloride has been shown to have a similar pharmacokinetic profile to cetirizine and can be used as an alternative for the treatment of allergic rhinitis.Formule :C19H21ClN2O2•(HCl)2Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :417.76 g/mol3'-N,N-Didesmethyl-N-(methoxycarbonyl) azithromycin
CAS :3'-N,N-Didesmethyl-N-(methoxycarbonyl) azithromycin is a research and development impurity standard. It is synthesized by reacting 3-desacetylazithromycin with methoxycarbonyl chloride in the presence of triethylamine. This product has been tested for purity by HPLC. CAS No. 16892-65-2Formule :C39H74N2O14Degré de pureté :Min. 95%Masse moléculaire :795.01 g/molEthyl 3-aminopyrazole-4-carboxylate
CAS :Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis.
Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyanFormule :C6H9N3O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :155.16 g/molFluticasone furoate impurity I
Fluticasone furoate impurity I is a drug product that is custom synthesized for research and development. It is an analytical standard that is used in metabolism studies. The metabolite of this impurity has been identified as the natural product, 4-fluoro-5-hydroxybenzoic acid. Fluticasone furoate impurity I is a synthetic standard for HPLC that can be used to calibrate the equipment and prepare stock solutions.Degré de pureté :Min. 95%
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