APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.203 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.974 produits)
- Dérivés de Quinazoline et de Quinoléine(66.218 produits)
- Quinones et Dérivés(24.378 produits)
- Sels et Dérivés d’API(92.894 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66870 produits trouvés pour "APIs pour la recherche et les impuretés"
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Phytofluene
CAS :Phytofluene is a natural compound that has been found to have potential as an anticancer agent. It acts as an inhibitor of cancer cell growth and induces apoptosis, or programmed cell death, in tumor cells. Phytofluene has been shown to inhibit the activity of several important proteins involved in cancer development, including chitinase and heparin-binding protein. It is derived from Chinese medicinal plants and has been used for centuries for its anti-inflammatory and antioxidant properties. In addition to its anticancer effects, phytofluene has also been found to inhibit the activity of kinases in human urine, suggesting a potential role in the treatment of other diseases such as diabetes and cardiovascular disease.Formule :C40H62Degré de pureté :Min. 95%Masse moléculaire :542.9 g/mol5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid
CAS :5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid is a synthetic drug that is used as an impurity standard. It has been shown to be metabolized by CYP450 enzymes and glucuronidases, and can inhibit the enzyme glutathione reductase. 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid also has been shown to have antiplatelet activity, which may be due to its ability to inhibit the enzyme ADP cyclase.Formule :C11H8FNO2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :205.18 g/molDes-His(1)-Semaglutide
Des-His(1)-semaglutide is a semaglutide-related impurity. This des-amino acid form has the histidine (His) amino acid from position 1 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.Formule :C181H284N42O58Masse moléculaire :3,976.5 g/molD-Ser(8)-Semaglutide
D-Ser(8)-Semaglutide is a semaglutide impurity. The amino acid at position 8 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/mol5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole
CAS :5-Methoxy-2-[(4-chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H benzimidazole is a synthetic drug product. It has been used as a positive control in metabolism studies and as an impurity standard. 5-Methoxy 2-[(4-chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfinyl]-5 methoxy 1H benzimidazole is also a metabolite of the active pharmaceutical ingredient (API) which is used to develop drugs. This chemical is synthesized by custom synthesis and can be obtained at high purity levels. The metabolite of this compound is 5 methoxy 2-[(4 chloro 3,5 dimethyl 2 pyridinyl)methyl]sulfonyl]-5 methoxy 1H benzimidazole.
Formule :C16H16ClN3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :349.84 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester
CAS :1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester is a creatine kinase inhibitor that blocks the synthesis of creatine phosphate, which is an important energy source for muscle contraction. Creatine kinase inhibitors are used in the treatment of congestive heart failure and myocardial infarct. They also have vasodilatory effects on blood vessels and can be used to treat hypertension. The elimination rate of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester depends on its formulation: solid dispersions have a half life of about 3 hours whereas orally administered doses have a half life of about 8 hours.Formule :C17H18N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :346.33 g/mol(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS :Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6Formule :C18H20N2O6Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :360.36 g/mol5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole
CAS :5-Methoxy-2-[[(3,5-dimethyl-2-pyridinyl)methyl]sulphinyl]-1H-benzimidazole is a natural product. It is an impurity in the drug development process and may be present as an analytical marker for impurities. 5-Methoxy-2-[(3,5-dimethylpyridinium)methyl]sulfinyl]-1Hbenzimidazole is used as a pharmacopoeia standard and can be synthesized on request.Formule :C16H17N3O2SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :315.39 g/molAll-trans-retinol-d5
CAS :Produit contrôléAll-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.
Formule :C20H25D5ODegré de pureté :(%) Min. 80%Couleur et forme :Clear Viscous LiquidMasse moléculaire :291.48 g/molRemdesivir impurity 6
CAS :Remdesivir impurity 6 is an impurity standard for a research and development drug product. It is a synthetic compound that has been custom synthesized for use in pharmacopoeia drug products. The purity of this compound is high and it has been shown to have no toxic effects on metabolism studies. Remdesivir impurity 6 is a metabolite of remdesivir, which is used as an antiviral agent for the treatment of HIV infection.Formule :C15H24NO5PDegré de pureté :Min. 95%Masse moléculaire :329.33 g/molCalcipotriol EP Impurity H
Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :807.19 g/molDapagliflozin Impurity 30
CAS :Dapagliflozin Impurity 30 is a natural impurity found in the drug Dapagliflozin. It is an analytical standard used for HPLC quantification of dapagliflozin, and it can be used as a pharmacopoeia reference material or research and development material. Dapagliflozin Impurity 30 is synthesized by using a custom synthesis protocol. The CAS number for this compound is 1373321-04-0.Formule :C21H25ClO6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :408.9 g/molDibenzosuberone
CAS :Dibenzosuberone is a reactive, surfactant, and β-catenin inhibitor that has been shown to have anti-cancer activity against solid tumours. It is synthesized by the asymmetric synthesis of dibenzoyl-L-tartaric acid with sodium dodecylsulfate in the presence of light. The substrate film is used to increase the rate of reactivity. Dibenzosuberone inhibits the growth of cancer cells by inhibiting cyclic peptide synthesis and blocking light emission from these cells. Dibenzosuberone also has an effect on cell migration and proliferation through its interactions with β-catenin. Dibenzosuberone hydrolyzes in aqueous solution to form benzene, which can be removed by adding hydrochloric acid or hydrogen bonding with anhydrous sodium.Formule :C15H12ODegré de pureté :Min. 95%Couleur et forme :Solidified MassMasse moléculaire :208.26 g/molUrolithin M5
CAS :Urolithin M5 is a drug product that has undergone custom synthesis, and is high in purity. It has CAS No. 91485-02-8, analytical data, metabolism studies, and drug development. Urolithin M5 is natural, with a metabolite pharmacopoeia and niche. There are impurities in this substance that are of synthetic origin and have an analytical HPLC standard. This substance has been researched and developed for use as an Impurity Standard.
Formule :C13H8O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :276.2 g/mol3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride
CAS :3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride is a Custom synthesis, drug product, Metabolite, Synthetic, Drug development, Impurity standard, Metabolism studies, API impurity, Natural and pharmacopoeia. 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride has CAS No. 76833-47-1 and is a High purity.Formule :C8H14N6S2·HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :294.83 g/molMethyl 2-[[3-trifluoromethyl)phenyl]amino]benzoate
CAS :Methyl 2-[[3-trifluoromethyl)phenyl]amino]benzoate is a bifunctional modulator of androgen receptors. It is a competitive inhibitor of the androgen receptor with an IC50 of 16 nM. Methyl 2-[[3-trifluoromethyl)phenyl]amino]benzoate has been shown to have weak binding affinity for the human androgen receptor, but it is not soluble in water and will require further research before it can be used clinically.Formule :C15H12F3NO2Degré de pureté :Min. 95%Couleur et forme :Pale yellow to yellow solid.Masse moléculaire :295.26 g/molIsoribavirin
CAS :Isoribavirin is a ribonucleoside monophosphate analog that inhibits viral RNA polymerase. Isoribavirin has been shown to be active against influenza virus, herpes simplex virus, and vesicular stomatitis virus in cell culture. Isoribavirin is stable in an acetonitrile solution in the presence of phosphoric acid at pH 3-4 or in the presence of sulfate ions at pH 9-10. It can be purified by chromatography on a silica gel column using an acetonitrile/water mobile phase gradient. The impurities of isoribavirin are not detectable by liquid chromatography and have no significant effect on its sensitivity. Isoribavirin elutes from the silica gel column with the impurities.
Formule :C8H12N4O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :244.21 g/mol2-(3-Hydroxy-2,2-Dimethylpropoxy)-1-(6-Hydroxy-2-Naphthyl)Propan-1-One
The following is a description of an impurity standard for the metabolite 2-(3-Hydroxy-2,2-Dimethylpropoxy)-1-(6-Hydroxy-2-Naphthyl)Propan-1-One:
Degré de pureté :Min. 95%
![5-Methoxy-2-[[(4-Chloro-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM57916.webp&w=3840&q=75)
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![Methyl 2-[[3-trifluoromethyl)phenyl]amino]benzoate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FIM58092.webp&w=3840&q=75)
