APIs pour la recherche et les impuretés
Les principes actifs pharmaceutiques (API) sont les substances présentes dans les médicaments qui sont responsables de leurs effets thérapeutiques. Dans cette section, vous trouverez une grande variété d'API destinés à un usage de recherche. Ces composés sont essentiels pour le développement, les tests et la validation de nouvelles formulations pharmaceutiques. Chez CymitQuimica, nous proposons des API de haute qualité pour soutenir la recherche dans la découverte et le développement de médicaments.
Sous-catégories appartenant à la catégorie "APIs pour la recherche et les impuretés"
- Acides Aminés et Dérivés(12.440 produits)
- Anthraquinones et Dérivés(407 produits)
- Dérivés du Benzimidazole et de l’Imidazole(10.464 produits)
- Dérivés des Benzodiazépines(335 produits)
- Glucides et Glycoconjugués(5.388 produits)
- Esters et Dérivés(42.306 produits)
- Acides Gras et Dérivés Lipidiques(32.486 produits)
- Flavonoïdes et Polyphénols(17.100 produits)
- Radicaux Libres et Agents Oxydants/Réducteurs(214 produits)
- Cétones et Dérivés(2.692 produits)
- Antibiotiques Naturels et Semi-Synthétiques(6.409 produits)
- Nitriles et Dérivés Cyano(3.070 produits)
- Nitrosamines et Dérivés(55 produits)
- Nucléosides et Nucléotides(3.492 produits)
- Phosphates et Phosphonates Organiques(1.203 produits)
- Sulfonates et Sulfates Organiques(10.451 produits)
- Composés Organométalliques(4.425 produits)
- Autres(6.340 produits)
- Peptides et Protéines(3.164 produits)
- Polymères et Dérivés(100 produits)
- Dérivés des Purines et Pyrimidines(8.974 produits)
- Dérivés de Quinazoline et de Quinoléine(66.218 produits)
- Quinones et Dérivés(24.378 produits)
- Sels et Dérivés d’API(92.894 produits)
- Stéroïdes et Dérivés(4.987 produits)
- Sulfamides et Dérivés(2.607 produits)
- Terpénoïdes et Dérivés(3.860 produits)
- Thiazolidinediones et Thiopyranes(2.755 produits)
- Composés β-Adrénergiques(231 produits)
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66870 produits trouvés pour "APIs pour la recherche et les impuretés"
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Calcipotriol EP Impurity H
Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.Formule :C54H78O5Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :807.19 g/mol4-(2-Methoxyethyl)phenol
CAS :4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.
Formule :C9H12O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :152.19 g/molD-Ser(11)-Semaglutide
D-Ser(11)-Semaglutide is a semaglutide impurity. The amino acid at position 11 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/mol4-Keto 13-cis-retinoic acid
CAS :4-Keto 13-cis-retinoic acid is a synthetic retinoid that was first synthesized in the 1970s. It is used for the treatment of ichthyosiform erythroderma and other skin diseases. 4-Keto 13-cis-retinoic acid binds to the retinoic acid receptor, which may be responsible for its effects on epidermal growth factor and cytosolic calcium. Treatment with 4-keto 13-cis-retinoic acid has been shown to inhibit the proliferation of hl-60 cells and squamous carcinoma cells in vitro, as well as reduce tumor size and metastasis in vivo. >>ENDFormule :C20H26O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :314.42 g/molParacetamol Impurity L
Paracetamol Impurity L is a drug product that is used as an analytical standard for the impurity paracetamol. It is found in pharmaceuticals, such as acetaminophen, which is used to relieve pain and reduce fever. Paracetamol Impurity L is a natural compound and has been shown to be metabolically stable in humans. The CAS number for this compound is 619-25-4.Formule :C16H16N2O4Degré de pureté :Min. 95%Masse moléculaire :300.31 g/molSimvastatin hydroxy acid ethyl ester
CAS :Simvastatin hydroxy acid ethyl ester is a solvated form of simvastatin, an investigational drug for the treatment of dyslipidemia. The ammonium salt was prepared by alcoholysis with ethanol. The elution process was carried out using an acetonitrile-water mixture and chromatography on silica gel. Preparation methods were investigated to determine the best preparative procedure that would yield pure material. This compound has been investigated as a possible therapeutic agent for the treatment of midbody diseases such as familial amyloidotic polyneuropathy and Alzheimer's disease.Formule :C27H44O6Degré de pureté :Min. 95%Couleur et forme :Colourless To Pale Yellow LiquidMasse moléculaire :464.63 g/molMethyl 2-disazobenzoate hydrochloride
CAS :Methyl 2-disazobenzoate hydrochloride is a drug product that is used as an HPLC standard and as a metabolite in the development of drugs. It has been found to be naturally occurring and is a research and development metabolite. Methyl 2-disazobenzoate hydrochloride is also an impurity of API, which can be quantified in analytical studies. It is a synthetic compound with CAS No. 35358-78-2 and it can be used to manufacture high purity pharmaceuticals. Methyl 2-disazobenzoate hydrochloride has been shown to have niche pharmacological effects, such as anti-inflammatory activities.Formule :C8H7N2O2ClDegré de pureté :Min. 95%Masse moléculaire :198.61 g/mol2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS :2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a synthetic building block which can undergo reaction with nucleophilic carbon species to afford C-ribosides (via the corresponding hemiacetal). Treatment of 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone with stronger reducing agents, such as sodium borohydride, affords ring opened products with a stereo-defined poly-oxygenated carbon chain backbone.Formule :C26H26O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :418.48 g/mol3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide
CAS :3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide is an impurity in the synthesis of a drug. It is not active and has no known therapeutic value. 3-Oxo-1,2-benzisothiazole-2(3H)-acetic acid ethyl ester 1,1-dioxide is used as a reference standard for HPLC and has been shown to be metabolized by cytochrome P450 enzymes.Formule :C11H11NO5SDegré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :269.27 g/molN-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine
CAS :N-Carbamoyl-N'-methyl-N''-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine is a sulfoxide that can be used as an analytical reagent for the determination of other substances. It is a colorless to white solid that can be prepared by reacting 1,4,5,6,7,8-hexahydroquinoline with methyl mercaptan and sodium hydroxide in ethanol. The detection limit for this compound is 0.01 mg/L. NCAIG has been used in the development of analytical methods for determining endogenous substances such as cyclic adenosine monophosphate (cAMP). This compound has also been used to determine steady state concentrations of drugs and endogenous substances in plasma or urine.Formule :C10H18N6OS·2HClDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :343.28 g/molrac-Diacetolol
CAS :Rac-Diacetolol is a racemic mixture of two isomers, (+) and (-), of acebutolol. Rac-Diacetolol is used to treat bowel disease, chronic oral inflammation and cardiac arrhythmias. It is also used as an experimental solubility probe in the study of the interactions between drugs and biological membranes. Rac-Diacetolol has been shown to have a low affinity for cytochrome P450 enzymes, which are responsible for metabolizing many drugs in the body. Rac-Diacetolol has been found to reduce plasma concentrations of PCSK9 antibody in patients with inflammatory bowel disease. The drug also has anti-inflammatory properties that may be due to its inhibition of prostaglandin synthesis.
Formule :C16H24N2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.37 g/molSemaglutide Impurity 29 (beta-Asp-9)
Beta-Asp-(9)-Semaglutide is a semaglutide impurity. The amino acid at position 9 has been replaced by the beta-aspartic acid (also known as isoaspartic, isoAsp, β-Asp or beta-Asp). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.Formule :C187H291N45O59Masse moléculaire :4,113.64 g/molDecitabine impurity 11
CAS :Decitabine is a drug product that is used as an anti-cancer drug. It is a synthetic, natural, and research and development (R&D) metabolite with the CAS No. 909402-26-2. Decitabine has shown anticancer activity in vitro and in vivo against leukemia cells. This compound is an impurity of the API decitabine that is manufactured by a chemical synthesis process. The analytical impurities are 11 compounds that have been identified from the HPLC standard of this API. The metabolites of these compounds are also included in this standard. High purity decitabine should be obtained for pharmacopoeia studies and niche applications such as HPLC standards, pharmaceuticals, or research purposes.Formule :C9H13N3O5Degré de pureté :Min. 95%Masse moléculaire :243.22 g/molChlorthalidone impurity H
CAS :Chlorthalidone impurity H is an impurity standard for chlorthalidone. It is a synthetic chemical and its CAS number is 2200280-98-2. It has the molecular formula C14H14ClN4O4S, molecular weight of 336.36 g/mol, and melting point of 174°C. Chlorthalidone impurity H is soluble in water and ethanol, but insoluble in ether or chloroform. It can be used as an analytical standard for HPLC and as an API impurity in the pharmacopoeia. This drug can also be used in drug development, natural product synthesis, metabolism studies, and drug product manufacturing.Formule :C17H17ClN2O4SDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :380.85 g/molOlsalazine sodium impurity G
Olsalazine sodium impurity G is an API impurity. It is an important impurity in the production of Olsalazine Sodium, which is a drug for the treatment of inflammatory bowel disease and ulcerative colitis. This compound has been shown to have a high purity level and a pharmacopoeia grade. The CAS number for this compound is 1209-03-9. This compound can be synthesized using organic chemistry methods, or it can be extracted from natural resources such as plants or animal tissues.Formule :C21H14N2O9Degré de pureté :Min. 95 Area-%Masse moléculaire :438.34 g/molAcyclovir acetate
CAS :Acyclovir is an antiviral agent that prevents the growth of herpes simplex virus. Acyclovir is a prodrug, which is converted to acycloguanosine 5'-triphosphate (ACV-TP) in vivo. ACV-TP inhibits viral DNA polymerase and thereby prevents viral genome replication, replication. The molecular structure of Acyclovir was determined by X-ray crystallography at 3.2 Å resolution. It has been shown that ACV-TP can be activated by chloride ions and it has been suggested that this activation may be the result of an interaction with a ligand.
ACV-TP binds to guanine residues in the DNA chain and prevents the formation of hydrogen bonds between guanine and adenine or cytosine residues in the same chain, preventing DNA replication.Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/molEsomeprazole sodium - EP
CAS :Esomeprazole sodium is a proton pump inhibitor that decreases the production of stomach acid. It is used in the treatment of symptoms such as heartburn, regurgitation, and ulcers caused by gastroesophageal reflux disease (GERD). Esomeprazole sodium has been shown to reduce the amount of acid produced in the stomach and to increase the pH level in the stomach. This drug also has significant interactions with other drugs, which can lead to an increased risk of adverse events. Esomeprazole sodium is excreted from the body through urine and feces. The active form of esomeprazole is also found in wastewater treatment plants and can contribute to antimicrobial resistance.Formule :C17H18N3NaO3SDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :367.4 g/molLevonorgestrel EP Impurity P
CAS :Soluble in Chloroform & in Methanol Confirmed
Insoluble in WateDegré de pureté :90% minCouleur et forme :Off White or Beige SolidMasse moléculaire :312.45
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