APIs pour la recherche et les impuretés

N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.

Tenofovir disoproxil is the disoproxil fumarate salt of tenofovir. It is a nucleoside reverse transcriptase inhibitor that has been shown to be effective in the treatment of chronic hepatitis B virus (HBV) in combination with emtricitabine and as a single agent in the treatment of HIV-1 infection. Tenofovir disoproxil is available as tablets, capsules, or oral solution. The drug has been shown to cause an increase in serum creatinine levels, which may be due to inhibition of renal tubular secretion of creatinine by tenofovir. This drug should not be used with alafenamide and tenofovir because it can lead to kidney failure and death.

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Daunorubicin metabolite

L-745,870 is a subchronic atypical antipsychotic agent that is a potent D4 receptor agonist. Its efficacy in treating various mental disorders has been demonstrated in clinical studies with animals. L-745,870 has shown antidyskinetic activity in animal models of Parkinson's disease and dyskinesia. The molecular target for this drug is the dopamine D4 receptor. Clinical development of L-745,870 has begun in human studies.

9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

Acyclovir Impurity O is an impurity found in the drug Acyclovir. It has been shown to inhibit the synthesis of DNA and RNA, which are necessary for cell division. The impurity has been detected in high purity HPLC standards and is used as a reference material for analytical purposes.
Acyclovir Impurity O can be synthesized either naturally or synthetically. It is an impurity that is regulated by the USP, BP, and EP pharmacopeias.

Bupropion is a racemic mixture of two enantiomers. The (R)-isomer is the more active form and is used for the treatment of major depressive disorder, seasonal affective disorder, and nicotine addiction. Bupropion has been shown to inhibit monoamine oxidase type A in humans and other mammals. This inhibition may be responsible for its antidepressant effects. The drug also has an effect on the liver, which can lead to serious side effects such as seizures or death if not monitored carefully. Bupropion has a high affinity for α1-acid glycoprotein, which plays a role in drug interactions with other drugs that are metabolized by this protein.

Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.

Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.

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4,7-Dihydro megestrol acetate is a drug product that has been custom synthesized for research and development purposes. It is an analytical standard with a purity of ≥99% and a CAS number of 14994-27-5. Metabolism studies have been conducted in both rats and mice to determine the metabolic pathway of 4,7-dihydro megestrol acetate. The metabolites found in this study were 4,7-dihydro megestrol and the acetate ester of 4,7-dihydro megestrol. Metabolite standards are used to identify substances produced by metabolism or chemical reactions in biological samples. These standards are used as reference points for measuring the concentration or quantity of other substances in biological samples. Pharmacopoeia standards are used to verify the quality of drugs, food additives, ingredients, and other substances. They also serve as reference points for identifying impurities in substances that may be harmful

Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

Meloxicam is a nonsteroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. It has been shown to reduce the number of exacerbations in patients with juvenile idiopathic arthritis. Meloxicam also inhibits the production of Cox-2, which is an enzyme that produces inflammation in joints. The oral route of administration allows meloxicam to be distributed through the body. This drug is not active against ankylosing spondylitis and it should not be taken by pregnant women or children under 12 years old.

1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.

1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration

4-Desfluoro-4-[4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-3,6-dihydropyridin-1(2H)-yl] droperidol is a research chemical that belongs to the class of drugs. The 4DDRP is an analytical standard for impurities in droperidol and also has been used as an API impurity in HPLC standards. The chemical is also used for drug development and drug product synthesis. 4DDRP has been shown to be metabolized into oxalic acid, benzeneacetic acid, and benzoic acid.

Pirtenidine is a potent and selective kinase inhibitor that has been shown to inhibit the activity of cyclin-dependent kinases. It has demonstrated promising results in preclinical studies as an anticancer agent, inducing apoptosis in cancer cells. Pirtenidine is an analog of protein kinase inhibitors, which have been used to treat various types of tumors. It has been found to be effective against human cancer cell lines and has shown significant tumor growth inhibition in animal models. Pirtenidine has also been reported to be a potent urine inhibitor of Chinese hamster ovary cells, making it a promising candidate for the treatment of urinary tract cancers.

Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.

Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is >99% (HPLC).

Dihydrexidine hydrochloride is a phosphate ion transport inhibitor that binds to the acetylcholine transporter, and inhibits the uptake of acetylcholine in the brain. It is used as an opioid analgesic, as well as to treat depression, cognitive disorders, and Parkinson's disease. Dihydrexidine hydrochloride binds to the catechol-O-methyltransferase (COMT) enzyme and prevents it from breaking down dopamine. This leads to increased levels of dopamine in the synapse and enhanced transmission of nerve impulses between neurons. Dihydrexidine hydrochloride also has been shown to bind to antigen molecules on cells, which may be important for its antiviral properties.

3'-[3-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-3,6-dihydro-5-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-3'-deoxythymidine is an analytical standard used in the R&D and drug development of 3'-azido derivatives of thymidine. It is a synthetic intermediate that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV) replication and to inhibit intracellular HIV type 2 (HIV2) production in cultured cells. 3'-[3-(3-Azido-2,3,-dideoxy--b erythro--pentofuranosyl)-3,6--dihydro--5--methyl--2,6--dioxo--1(2H)--pyrimidinyl]-

Elsinochrome A is a drug product that has not been approved for human use. It belongs to the class of drugs called natural products and has not been synthesized. Elsinochrome A is a metabolite of erythromycin, which is produced by the fungus Elsinoë sp. The chemical structure of this natural product was determined using spectral analysis, and it was found to be similar to the antibiotic erythromycin. Elsinochrome A has shown promising results in pharmacological studies as a potential drug candidate for tuberculosis treatment because it inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication.

Remdesivir related compound 7 is a drug product that is being synthesized for use in research and development. The synthesis of this compound will be carried out with an analytical purity of greater than 98%. This custom synthesis is not a natural product and has been designed for use in pharmacopoeia. Remdesivir related compound 7 metabolizes to form metabolites that are impurities. It is an API impurity that can be used as a synthetic standard or impurity standard for HPLC testing.

Tetracosanoic acid is a drug product that is used in the development of drugs and as an analytical standard. Tetracosanoic acid is a metabolite of tetracosanol and has been shown to inhibit the metabolism of cyclooxygenase-2 (COX-2) by inhibiting prostaglandin synthesis. Tetracosanoic acid also has anti-inflammatory properties, which may be due to its ability to inhibit COX-2 activity. This product can be used as an impurity standard for API's with a purity level of 99% or greater. Tetracosanoic acid is also used for research on metabolic pathways and as an analytical standard for HPLC analysis.

Spirolaxine is a coumarin derivative that has been shown to have anti-cancer properties. It was isolated from an extract of the fungus Spirolaxine, which was found in the gastroduodenum (gut) of a frog. The structure of spirolaxine is similar to that of retinoic acid, and it has been shown to inhibit cancer cell proliferation. Spirolaxine also inhibits the production of proinflammatory cytokines in mice with colitis. This drug has not yet been tested for its ability to treat other diseases, such as diabetes, but may be able to regulate blood sugar levels by inhibiting insulin secretion and increasing glucose uptake by cells.

Streptonigrin is an anticancer drug that is derived from the bacterium Streptomyces flocculus. It has been shown to induce apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases and protein kinases. Streptonigrin has been found to be effective against a variety of tumors, including those of Chinese hamster ovary cells and human urine-derived cancer cells. This inhibitor analog also has a potent inhibitory effect on tumor growth in vivo.

(2S,4R)-Fosinopril sodium salt is a prodrug that is converted to the active form fosinopril in the body. It is used to treat high blood pressure and heart failure. Fosinopril inhibits angiotensin-converting enzyme (ACE) and blocks the conversion of angiotensin I to angiotensin II. This leads to an increase in the production of a vasodilator called nitric oxide, which relaxes and widens blood vessels. Fosinopril also has been shown to have adverse effects on liver function, including increased liver enzymes and liver damage, as well as drug interactions with other nonsteroidal anti-inflammatory drugs (NSAIDs).

Pseudomonic acid D sodium is a drug product that is used for the development of novel drugs. It is a natural metabolite of pseudomonic acid A, which is found in the fungus Pseudomonas sp. Pseudomonic acid D sodium is used as an analytical standard to aid in the identification of pseudomonic acid A and its metabolites. Pseudomonic acid D sodium can be synthesized by reacting 2-chloro-4-nitrobenzene with sodium bisulfate. The synthesis proceeds through a sequence of three reactions, namely nucleophilic substitution, electrophilic substitution, and hydrolysis. The structure of pseudomonic acid D sodium has been confirmed using nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS).

Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.

1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is >98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.

Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.

Trazodone Impurity A is a drug product that is an impurity standard for Trazodone. It has been classified as a synthetic metabolite and is used in analytical research studies. Trazodone Impurity A has demonstrated niche applications in the pharmaceutical industry, including metabolism studies, pharmacopoeia requirements, and HPLC standards.

1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic acid (1bRT) is an amide that inhibits the growth of viruses by inhibiting the viral enzyme thiosemicarbazide. It has been shown to be active against specific viruses such as HIV and retroviruses. 1bRT is used to treat lung diseases caused by viruses, including bronchiolitis, pneumonia, and pulmonary fibrosis. It also has antibacterial properties. Studies have shown that 1bRT reduces the number of bacteria in body fluids and helps to prevent respiratory infections and other bacterial infections in people with weakened immune systems due to AIDS or cancer treatment.

O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.

Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

Desfluoro impurity is a drug product that is an analytical standard for the identification of impurities in API. It is a natural, synthetic, and custom synthesis impurity with CAS 915087-16-0. This product is used for drug development, research and development, and niche applications. Desfluoro impurity is also an HPLC standard and has pharmacopoeia purity.

N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.

Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.

2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is a synthetic, nonsteroidal anti-inflammatory drug. It is soluble in methanol and ethanol, not soluble in water. The impurity standard of 2-[[[3-Methyl-4-(methylthio)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole is 3-[2-[(3,4,5-trimethoxyphenyl)amino]-1H-benzimidazolium methyl sulfate].

Preterramide C is a drug that belongs to the class of drugs known as aminopyridines. It is a metabolite of preterramide A and has been used as an analytical reference standard for HPLC. This product is available in the form of a pure white crystalline powder with a purity greater than 98%. It has been shown to be an impurity in drug products and can be used as an impurity standard, as well as being synthesized by natural or synthetic means.

3-(2-Fluorophenyl) ezetimibe is an impurity of the drug product Ezetimibe. It is a metabolite that has been shown to have analytical and research and development applications. 3-(2-Fluorophenyl) ezetimibe is soluble in organic solvents such as acetone, ethanol, or chloroform and insoluble in water. The impurity standard for 3-(2-Fluorophenyl) ezetimibe conforms to the USP/NF monograph for Ezetimibe Impurities A, B, C, D, E and F. The CAS number for this impurity is 1798008-25-9.

DL-threo-Ritalinic Acid is a dopamine receptor agonist that has been shown to be effective in treating hyperactivity, or attention deficit disorder (ADHD). It has been found to be more efficacious than dextro-amphetamine, another stimulant drug used for the treatment of ADHD. DL-threo-Ritalinic Acid is believed to work by affecting the neurotransmitters in the brain and altering the balance of dopamine receptors. In a two-way crossover study, preschool children were given either 0.5mg/kg of DL-threo-Ritalinic Acid or placebo for three days. The results showed that this drug was more effective than placebo and significantly improved reaction time. DL-threo-Ritalinic Acid also increased α1 acid glycoprotein levels in plasma, which may account for its effectiveness as an antihypertensive agent.

RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.

9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.

Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

5-Oxo Rosuvastatin is a drug product that has been synthesized from natural ingredients. It is an analytical standard for the impurity, 5-oxo-rosuvastatin, which is a potential impurity in the API, rosuvastatin. This drug product has been custom synthesized in order to provide an Impurity Standard for HPLC. This drug product is also used as a Synthetic Reference Standard for Drug Development and Research and Development.

6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

L-Valine 2-hydroxyethyl ester tosylate (L-V2HT) is a drug product that is synthesized by custom synthesis. It has high purity, analytical, and natural properties. L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The active form of L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. L-V2HT also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell

Roxithromycin impurity I is a natural metabolite of roxithromycin. The substance has been synthesized in order to serve as an analytical impurity standard for HPLC. Roxithromycin impurity 1 is also a metabolite of roxithromycin, which has been shown to produce pharmacological effects similar to those seen with the parent compound. Roxithromycin impurity I is not an API, but has been developed as a HPLC analytical impurity standard and will be used for metabolism studies.

N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)-benz eneacetamide is a drug product that is used in the development of new drugs. It is an analytical standard for HPLC and was created as a natural metabolite from the antibiotic Cefazolin. N-[1-[3-(4-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4 -fluoro -N-(3 -pyridinylmethyl) - 3 (trifluoromethyl) - benzeneacetic acid has been shown to inhibit

Tiotropium EP Impurity I is an impurity found in the API, Tiotropium EP. It is a natural product that is synthesized by chemical synthesis. The synthetic purity of Tiotropium EP Impurity I is high and complies with pharmacopoeia guidelines. This impurity can be used as a standard to test the quality of other products or to research the metabolism of Tiotropium EP.

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Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.

Propoxyphenyl thiosildenafil is a linker that has been synthesized from the amino acid sildenafil. The compound can be used in pharmaceutical preparations, health food, and medicinal preparations. It is also used as an additive to prepare the desired drug. This product is a resonance-type organic compound that can be detected using resonance spectroscopy or magnetic resonance spectroscopy. The compound has a molecular weight of 348.08 g/mol and a boiling point of 440°C at 760 mmHg pressure.

Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.

17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.

Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.

Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.

Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.

Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.

Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

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Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.

Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.

N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.

Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.

(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.

Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.